LOCUS       DAVDZK010000001       142668 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVDZK010000001 DAVDZK010000000
VERSION     DAVDZK010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 142668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 142668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..142668
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.001"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            178..498
                     /locus_tag="VUX16_000001"
     CDS             178..498
                     /locus_tag="VUX16_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET8123069.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            544..852
                     /locus_tag="VUX16_000002"
     CDS             544..852
                     /locus_tag="VUX16_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET8123070.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            869..2161
                     /locus_tag="VUX16_000003"
     CDS             869..2161
                     /locus_tag="VUX16_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET8123071.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFETMIPAFVIFLSSMIVYILASSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAAIVYGSIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKIQDRLAYQNEIK"
     gene            2318..4756
                     /locus_tag="VUX16_000004"
     CDS             2318..4756
                     /locus_tag="VUX16_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET8123072.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELELFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDSASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            4775..5443
                     /locus_tag="VUX16_000005"
     CDS             4775..5443
                     /locus_tag="VUX16_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET8123073.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            5461..6549
                     /locus_tag="VUX16_000006"
     CDS             5461..6549
                     /locus_tag="VUX16_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET8123074.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            7004..9505
                     /locus_tag="VUX16_000007"
     CDS             7004..9505
                     /locus_tag="VUX16_000007"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET8123075.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLTAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLIEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            9699..10394
                     /locus_tag="VUX16_000008"
     CDS             9699..10394
                     /locus_tag="VUX16_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8123076.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            10406..10822
                     /locus_tag="VUX16_000009"
     CDS             10406..10822
                     /locus_tag="VUX16_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8123077.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(11650..11742)
                     /locus_tag="VUX16_000010"
     CDS             complement(11650..11742)
                     /locus_tag="VUX16_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET8123078.1"
                     /translation="MMELILKTIIGPIVVGVVLRLVDKWLNKDR"
     gene            complement(12083..12175)
                     /locus_tag="VUX16_000011"
     CDS             complement(12083..12175)
                     /locus_tag="VUX16_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET8123079.1"
                     /translation="MMDTILKTIIGPIVVGVVLRLVDKWLNKDK"
     gene            complement(12490..12582)
                     /locus_tag="VUX16_000012"
     CDS             complement(12490..12582)
                     /locus_tag="VUX16_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET8123080.1"
                     /translation="MMELVLKTIIGPFVVGVVLRLVDKWLNKDK"
     gene            12742..13713
                     /gene="ruvB"
                     /locus_tag="VUX16_000013"
     CDS             12742..13713
                     /gene="ruvB"
                     /locus_tag="VUX16_000013"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET8123081.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNDLEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDVITDKALTMLDVDHEGLDYVDQKILRTMIEMYGGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRMATAKAYEHLGYEYNEK"
     gene            13694..14266
                     /locus_tag="VUX16_000014"
     CDS             13694..14266
                     /locus_tag="VUX16_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET8123082.1"
                     /translation="MSTMKNKQEILESFRKNPDMMAILTIIQNLELTDSWLAAGSVRN
                     FIWNLLSDKSPFDFETDVDVIFFDPDISYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTAPYTSSRDAMSKYPERCTAVGLRLNEEPALELFTPYGLEDILNFQVRPTPHFL
                     ENQERMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            14497..15255
                     /locus_tag="VUX16_000015"
     CDS             14497..15255
                     /locus_tag="VUX16_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET8123083.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEVALQEAILAYNRRHRRFGGV"
     gene            15264..16067
                     /locus_tag="VUX16_000016"
     CDS             15264..16067
                     /locus_tag="VUX16_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET8123084.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            16089..17348
                     /gene="rseP"
                     /locus_tag="VUX16_000017"
     CDS             16089..17348
                     /gene="rseP"
                     /locus_tag="VUX16_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET8123085.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            17361..19214
                     /locus_tag="VUX16_000018"
     CDS             17361..19214
                     /locus_tag="VUX16_000018"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET8123086.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            19313..20692
                     /gene="bglA"
                     /locus_tag="VUX16_000019"
     CDS             19313..20692
                     /gene="bglA"
                     /locus_tag="VUX16_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET8123087.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVLAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            20885..22693
                     /gene="glmS"
                     /locus_tag="VUX16_000020"
     CDS             20885..22693
                     /gene="glmS"
                     /locus_tag="VUX16_000020"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET8123088.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDSNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEVGQ
                     VVVDQAIIQAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANHTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEVKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLTLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKETDAIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            23138..24907
                     /locus_tag="VUX16_000021"
     CDS             23138..24907
                     /locus_tag="VUX16_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HET8123089.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGSLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPIANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMLIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDISTSASVDSQEIDFNHIDAVVVAYGKAQ
                     GSATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQTAPNS
                     QFLIVDSLVTTPEYDKMAVRMYK"
     gene            24931..26886
                     /locus_tag="VUX16_000022"
     CDS             24931..26886
                     /locus_tag="VUX16_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET8123090.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECMKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            26888..27325
                     /locus_tag="VUX16_000023"
     CDS             26888..27325
                     /locus_tag="VUX16_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET8123091.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            27387..28523
                     /locus_tag="VUX16_000024"
     CDS             27387..28523
                     /locus_tag="VUX16_000024"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HET8123092.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKSGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLITKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDPELIEQIVEYI"
     gene            28775..29824
                     /locus_tag="VUX16_000025"
                     /pseudo
     CDS             28775..29824
                     /locus_tag="VUX16_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
     gene            complement(29924..33694)
                     /gene="spuA"
                     /locus_tag="VUX16_000026"
     CDS             complement(29924..33694)
                     /gene="spuA"
                     /locus_tag="VUX16_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET8123093.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDATSIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEVHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGPVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVRNESV
                     ENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN"
     gene            33981..35327
                     /locus_tag="VUX16_000027"
     CDS             33981..35327
                     /locus_tag="VUX16_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HET8123094.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVANMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPGRKASLMMH"
     gene            35819..36232
                     /gene="rpsL"
                     /locus_tag="VUX16_000028"
     CDS             35819..36232
                     /gene="rpsL"
                     /locus_tag="VUX16_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET8123095.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            36252..36722
                     /gene="rpsG"
                     /locus_tag="VUX16_000029"
     CDS             36252..36722
                     /gene="rpsG"
                     /locus_tag="VUX16_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET8123096.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            37147..39228
                     /gene="fusA"
                     /locus_tag="VUX16_000030"
     CDS             37147..39228
                     /gene="fusA"
                     /locus_tag="VUX16_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET8123097.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            39332..43723
                     /locus_tag="VUX16_000031"
     CDS             39332..43723
                     /locus_tag="VUX16_000031"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET8123098.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     GAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            43825..44088
                     /locus_tag="VUX16_000032"
     CDS             43825..44088
                     /locus_tag="VUX16_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET8123099.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            44081..44359
                     /locus_tag="VUX16_000033"
     CDS             44081..44359
                     /locus_tag="VUX16_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET8123100.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            44380..44532
                     /locus_tag="VUX16_000034"
     CDS             44380..44532
                     /locus_tag="VUX16_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123101.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            44554..45795
                     /locus_tag="VUX16_000035"
     CDS             44554..45795
                     /locus_tag="VUX16_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET8123102.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            45805..46035
                     /locus_tag="VUX16_000036"
     CDS             45805..46035
                     /locus_tag="VUX16_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET8123103.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            46303..47025
                     /locus_tag="VUX16_000037"
     CDS             46303..47025
                     /locus_tag="VUX16_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET8123104.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            47242..48576
                     /gene="pepC"
                     /locus_tag="VUX16_000038"
     CDS             47242..48576
                     /gene="pepC"
                     /locus_tag="VUX16_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET8123105.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(48632..49543)
                     /locus_tag="VUX16_000039"
     CDS             complement(48632..49543)
                     /locus_tag="VUX16_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET8123106.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(49567..50370)
                     /locus_tag="VUX16_000040"
     CDS             complement(49567..50370)
                     /locus_tag="VUX16_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET8123107.1"
                     /translation="MSIISMVLVIVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(50398..51387)
                     /gene="manX"
                     /locus_tag="VUX16_000041"
     CDS             complement(50398..51387)
                     /gene="manX"
                     /locus_tag="VUX16_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET8123108.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(51620..52639)
                     /gene="adhP"
                     /locus_tag="VUX16_000042"
     CDS             complement(51620..52639)
                     /gene="adhP"
                     /locus_tag="VUX16_000042"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET8123109.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIATADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(52978..53790)
                     /locus_tag="VUX16_000043"
     CDS             complement(52978..53790)
                     /locus_tag="VUX16_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET8123110.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            53980..55398
                     /locus_tag="VUX16_000044"
     CDS             53980..55398
                     /locus_tag="VUX16_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET8123111.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            55451..56158
                     /locus_tag="VUX16_000045"
     CDS             55451..56158
                     /locus_tag="VUX16_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET8123112.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTVVFALLHQPSNLPSLLIYGGMSIVLSWTAYKTQRLEMSILLHMIVNGVAF
                     CLLALVVILSRTLGISV"
     gene            56252..57229
                     /gene="folP"
                     /locus_tag="VUX16_000046"
     CDS             56252..57229
                     /gene="folP"
                     /locus_tag="VUX16_000046"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET8123113.1"
                     /translation="MVKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGRSSYVEIEEEIQRVVPVIKAIRKESNVLISID
                     TWKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVIARPQHPSSL
                     IFPHFGFGQAFTEKELADFETLPIEDLMETFFDRALARAEEAGIAQENILLDPGIGFG
                     LTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTA
                     SAHVTSIAVRQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            57231..58553
                     /locus_tag="VUX16_000047"
     CDS             57231..58553
                     /locus_tag="VUX16_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET8123114.1"
                     /translation="MKEFENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVIHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMADY
                     RSLLEGESATNLQGTTEFEIITAIAYDYFALEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGTPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALGDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            58534..59088
                     /gene="folE"
                     /locus_tag="VUX16_000048"
     CDS             58534..59088
                     /gene="folE"
                     /locus_tag="VUX16_000048"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET8123115.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            59131..59943
                     /gene="folB"
                     /locus_tag="VUX16_000049"
     CDS             59131..59943
                     /gene="folB"
                     /locus_tag="VUX16_000049"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HET8123116.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFETYPLVQEIKLELKKPWA
                     PVHLPLDTCSVTIHRRKQRAFIALGSNMGDKQANLEQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVIEVETWLPAPVLLETLLAIESEMGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIASHFIHPTLKQPIRNLYNALKK"
     gene            complement(59988..60305)
                     /locus_tag="VUX16_000050"
     CDS             complement(59988..60305)
                     /locus_tag="VUX16_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET8123117.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPLYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            60662..61108
                     /gene="rplM"
                     /locus_tag="VUX16_000051"
     CDS             60662..61108
                     /gene="rplM"
                     /locus_tag="VUX16_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET8123118.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            61128..61520
                     /gene="rpsI"
                     /locus_tag="VUX16_000052"
     CDS             61128..61520
                     /gene="rpsI"
                     /locus_tag="VUX16_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET8123119.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(61782..62204)
                     /locus_tag="VUX16_000053"
     CDS             complement(61782..62204)
                     /locus_tag="VUX16_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET8123120.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            62351..62527
                     /locus_tag="VUX16_000054"
     CDS             62351..62527
                     /locus_tag="VUX16_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123121.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            62929..65142
                     /locus_tag="VUX16_000055"
     CDS             62929..65142
                     /locus_tag="VUX16_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HET8123122.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHCYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(65364..65840)
                     /locus_tag="VUX16_000056"
     CDS             complement(65364..65840)
                     /locus_tag="VUX16_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET8123123.1"
                     /translation="MTSLYDFSFLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLQDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            66063..69092
                     /locus_tag="VUX16_000057"
                     /pseudo
     CDS             66063..69092
                     /locus_tag="VUX16_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884539.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            69150..69266
                     /locus_tag="VUX16_000058"
                     /pseudo
     CDS             69150..69266
                     /locus_tag="VUX16_000058"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            69647..70023
                     /gene="tnpA"
                     /locus_tag="VUX16_000059"
                     /pseudo
     CDS             69647..70023
                     /gene="tnpA"
                     /locus_tag="VUX16_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(70410..71039)
                     /locus_tag="VUX16_000060"
     CDS             complement(70410..71039)
                     /locus_tag="VUX16_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET8123124.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNPYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(71049..72050)
                     /locus_tag="VUX16_000061"
     CDS             complement(71049..72050)
                     /locus_tag="VUX16_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET8123125.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGYRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRTILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFVRFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(72081..72722)
                     /locus_tag="VUX16_000062"
     CDS             complement(72081..72722)
                     /locus_tag="VUX16_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET8123126.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     NPLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVVPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(72741..73556)
                     /locus_tag="VUX16_000063"
     CDS             complement(72741..73556)
                     /locus_tag="VUX16_000063"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET8123127.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEVGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASDFVNGHILYVDGGILAYIGKQPE"
     gene            73827..74261
                     /locus_tag="VUX16_000064"
     CDS             73827..74261
                     /locus_tag="VUX16_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET8123128.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            74273..75463
                     /locus_tag="VUX16_000065"
     CDS             74273..75463
                     /locus_tag="VUX16_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET8123129.1"
                     /translation="MIKKVTIEEIKSPERFLEVPLLTKEEVDQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDEFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYVSANNVIRDDASSFHT
                     FYFDPETGQPLKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            75474..75965
                     /locus_tag="VUX16_000066"
     CDS             75474..75965
                     /locus_tag="VUX16_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET8123130.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGGEDKAALKELNQTYQVTFNTKTTPTGNDGAVEVNIM
                     DYI"
     gene            75980..76759
                     /locus_tag="VUX16_000067"
     CDS             75980..76759
                     /locus_tag="VUX16_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET8123131.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            76746..77564
                     /locus_tag="VUX16_000068"
     CDS             76746..77564
                     /locus_tag="VUX16_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET8123132.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADTKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKILA"
     gene            77564..77857
                     /gene="yajC"
                     /locus_tag="VUX16_000069"
     CDS             77564..77857
                     /gene="yajC"
                     /locus_tag="VUX16_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET8123133.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRKEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            77879..79780
                     /locus_tag="VUX16_000070"
     CDS             77879..79780
                     /locus_tag="VUX16_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET8123134.1"
                     /translation="MKEERRQFFEKIDGDQYRDYILSHCSQDYEKVKRSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWNQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKGYI
                     QKCKFFLFDWIEQVREFRPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEEELENIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPILATYHFFSDKMDLEEAYHFASKELKQQ
                     IETQILEDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSFQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAMVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKFRSFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDT
                     GRYSYREVDERYLLKSAWSHSTCIVDGKAPERIVGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYLSAEPDLPYLHRRKILMLAEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLKLWSEVDFDLEATIISPKYNELEKSSKLIKHQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDGHQVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            79840..80841
                     /locus_tag="VUX16_000071"
     CDS             79840..80841
                     /locus_tag="VUX16_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET8123135.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIKKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSTQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSRLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHARLT
                     IEDKHTNLEQIKEFLQKEINPDEKTLVFVPNCWALPPVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPAFEEGQQATKILIDQIEGLNQEERQQVLDCSVSWKESTF"
     gene            complement(81112..81690)
                     /locus_tag="VUX16_000072"
     CDS             complement(81112..81690)
                     /locus_tag="VUX16_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET8123136.1"
                     /translation="MKKEDLTTRLLRNLFHIQGPFDECRQEIIYKACARSMVQIVYSS
                     FFLFLFYLLFGRFIEAVRYAMPYVYSGLIFFITLKTQRVVKELHMEKDDKSEIILKTY
                     SKAQIKFRSWIVFIGLQIGLFTLLIFHKVFVQQMSLSDFVKLLMQFDKSVPFLMYGLI
                     IGSIFGTLTYGFLSLQEEKIPKNTKQKEKSKQ"
     gene            complement(81717..82040)
                     /locus_tag="VUX16_000073"
     CDS             complement(81717..82040)
                     /locus_tag="VUX16_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123137.1"
                     /translation="MKSLLTLLTYHLLFSSLLIFIIVSGNLIREIFLVLVFVPALNKV
                     LTYLKIDSPKTRTLNLALYFMILSFPQLMLVSGNWNYYLLLTIASLSSIIYLYYLYQF
                     VKENQ"
     gene            complement(82051..82293)
                     /locus_tag="VUX16_000074"
     CDS             complement(82051..82293)
                     /locus_tag="VUX16_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123138.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVILFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(82304..82846)
                     /locus_tag="VUX16_000075"
     CDS             complement(82304..82846)
                     /locus_tag="VUX16_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET8123139.1"
                     /translation="MKKETFTEKLIKRTYGISDPLDEYKRREADRIGNQVFIFLFYLM
                     IFGNLIPLLLAYKYPQLVALVYPPLILVIALIVAGYLTYQMQKTGITTIEPDMLNEKE
                     SKQLHYPGLKAGIVYGLMSFFTTPLLHILLGESQDYLQSLLAFKNIFSSILQSVFFGV
                     VIQILISRRIAKARKNQDND"
     gene            complement(82857..83399)
                     /locus_tag="VUX16_000076"
     CDS             complement(82857..83399)
                     /locus_tag="VUX16_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET8123140.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADRIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITAIDPDMLSEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKDQDED"
     gene            complement(83415..83609)
                     /locus_tag="VUX16_000077"
     CDS             complement(83415..83609)
                     /locus_tag="VUX16_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8123141.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            83776..84726
                     /gene="rsmH"
                     /locus_tag="VUX16_000078"
     CDS             83776..84726
                     /gene="rsmH"
                     /locus_tag="VUX16_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET8123142.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMEMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            84738..85055
                     /gene="ftsL"
                     /locus_tag="VUX16_000079"
     CDS             84738..85055
                     /gene="ftsL"
                     /locus_tag="VUX16_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET8123143.1"
                     /translation="MAERMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            85059..87311
                     /locus_tag="VUX16_000080"
     CDS             85059..87311
                     /locus_tag="VUX16_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HET8123144.1"
                     /translation="MKWTKKVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQ
                     MDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEGITEDFVWRDILYQSNYE
                     PGSAMKVMTLASSIDNNTFPSGEYFNSSEFKIADATTRDWDVNDGLTTGGMMTFLQGF
                     AHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIAQSSF
                     GQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPVSKEAA
                     STTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGST
                     NYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSPA
                     KNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAP
                     NQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGSVVQKQDVRTNTAIKN
                     IKKIKLTLGD"
     gene            87313..88293
                     /locus_tag="VUX16_000081"
     CDS             87313..88293
                     /locus_tag="VUX16_000081"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET8123145.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLIAAVVVSFLLALFSKQLTNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVVFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKMTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            88950..91055
                     /locus_tag="VUX16_000082"
     CDS             88950..91055
                     /locus_tag="VUX16_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET8123146.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLAGNAEVDGKMPQQPSGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QEASEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEVGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     EAEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGATDIERLKDMGHRLQTKVIGQDKAVEAVAKAIRRNRAGFDEGNRPIGSFLF
                     VGPTGVGKTELAKQLALDMFGTKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKEIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(91226..91708)
                     /locus_tag="VUX16_000083"
     CDS             complement(91226..91708)
                     /locus_tag="VUX16_000083"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET8123147.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAEIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(91803..93287)
                     /locus_tag="VUX16_000084"
     CDS             complement(91803..93287)
                     /locus_tag="VUX16_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET8123148.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGESPYA
                     SPTDMGVNMVGFAITDNEAAIEASKQEIIRRYYQTVLDFKAEKVSESAVKKIELLMND
                     LGITPSDRKVAVVARQKAEETGGPALALELPSGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPELVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            93440..95050
                     /locus_tag="VUX16_000085"
     CDS             93440..95050
                     /locus_tag="VUX16_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET8123149.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKNLLTVGETWGATPAIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVSMEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEEINVQEALANPDSIFYTYKKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGTVKSV
                     LIENTTAQEVFEKQILAPWDAFCVELTD"
     gene            95320..97287
                     /locus_tag="VUX16_000086"
     CDS             95320..97287
                     /locus_tag="VUX16_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET8123150.1"
                     /translation="MQSKKWLIGAGVTLSTAILLTACGKSEKNADAPKTFSYVYAVDP
                     SSLDYSLTSKSSTSDVIGNVVDGLLENDKYGNLIPSLAEDWSVSKDGLTYTYKLRKGV
                     KWYTSEGEEYAEVKAQDFVTGLKHAADGKSDGLSLVEKSIKGLEAYVSGETNDFSTVG
                     VKALDDYTVEYTLNNPESFWNSKVTTATMLPVNEEFLNATGKDYGAPTPSSILYNGPY
                     FLKSLISKSVIEYEKNPNYWDKDNVKIDNVKLTFYDGSDQESLIRSFTQGAYTTARLF
                     PASSNFESTKKEYGDKIVYSPQEATSYYLTVNVNRQSYNKTAKTDESQKTSTKEALLN
                     KNFRQALNFAFNRHAYTAQLNGEEGADKIIRNSLVPDNYVQVAGKTFGQLAQDELLKY
                     GEQWKDVTLTDGKDTIYNPTKAKSAFEKAKSELQAKGVSFPIHLDVPVEQTDVVAVQQ
                     TNSLKQSIEETLGTENVIIDVLQMTDNEKESITSQAKVPTQKDYDLNGTGWGPDYQDP
                     ATYLNILDAKKGSALKHLGITKGKDPEVVAKVGLDEYKKLLDDAASETSNLDKRYEKY
                     AKAQAWVTDSSLLIPVASSGGSPMVSRTVPFTKAYSQVGIKGDPFIFKGMELQNDIVT
                     TKEYDAAFKKWQKEKLESNAQYQKDLEKHIK"
     gene            97514..99472
                     /locus_tag="VUX16_000087"
     CDS             97514..99472
                     /locus_tag="VUX16_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET8123151.1"
                     /translation="MTTKKRILSAGLTFAAALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNTAIITNLVDGLLENDNHGNLVPSLAEDWSVSSDGLTYTYKLRKDAKWF
                     TADGEEYAPVKAQDFVTGIKYAVDNKSQAIDLIQNSIKGLNDYITGADSDFSKVGVKA
                     IDDQTVEYTLTRPEPYWNSKTTNSILFPVNEEFLNSKGKDFGTLSPDSILYSGPYLLK
                     DFTSKSSIEYVKNPHYYDHDKVSIEHVKLAYFDGSDQELTIRNFESGAYSIAGVYPNS
                     SNFAKTKEKYKDNIVYSLQDKTSWYFNFNVNRKAYNHTSKTTDEQKKSTETAVLNKNF
                     RQAVNFALDRTAYSAQSNGEEAASKTLRNTLVPPTFVQVGDKTFGEVVASKLVNYGTE
                     WSGINLADAQDAYFNKEKAQAKFVEAKKELASQGVTFPIHLDVAVDQTSKNAVTGMNS
                     VKQTLESVLGADNVVIDVQQLSTDDFNNVAFLAPTAADRDYDLNFDGWVGDYQDPSTY
                     LNPFNAEDGFYLKIFGLDAKEDKEKITSLGLDTYTKMLKDADSENKDVAKRYEKYAEA
                     QAWMIDNSLIMSAMSSGGTASVTKVTPFTRGYSLVGIKGDGNNYKYMKLQKDTVTTKQ
                     FEEAKTKWEQESKKAIEKAQKEAEKHVK"
     gene            99805..100905
                     /gene="glf"
                     /locus_tag="VUX16_000088"
     CDS             99805..100905
                     /gene="glf"
                     /locus_tag="VUX16_000088"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HET8123152.1"
                     /translation="MYDYLIVGAGLSGAIFAYEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGVNVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWETKTPQEVKDKIAEQTAHMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     TDLPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGLDFFANRQ
                     ELEASAEKVVFTGMIDQYFDYKHGELEYRSLRFEHEVLNEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGTQAKTVITREYPADWKRGDEPYYPINDERNNAIFAKYQEEAATNDK
                     VIFCGRLADYKYYDMHVVIERALEVVAEELGQ"
     gene            101142..103121
                     /locus_tag="VUX16_000089"
     CDS             101142..103121
                     /locus_tag="VUX16_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET8123153.1"
                     /translation="MKTRKVLALAGVTLLAAGVLAACSGGSGAQGEKTFAFTYETHPD
                     NLNYLTTGKAATSEITSNVIDGLLENDKYGNLIPSMAEDWSVSKDGLTYTYKIRQDAK
                     WYTSEGEEYAPVKAQDFVTGLKYATDKKAEALYLVQDSIKGLDAYAKGEITDFAQVGI
                     KALDDQTVQYTLNKPETFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGPY
                     LLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARLY
                     PTSASFAELEKSMKDNIVYTQQDSTTYLVGTNIDRQSYKHTSKTSDEQKTSTKKALLN
                     KDFRQAIAFGFDRTAYASQLNGETGASKILRNLFVPPTFVQADGKNFGDIVKEKLVTY
                     GDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQR
                     VQSMKQSLEATLGTDNVVIDIQQLQKDELLNVTLFAENAAGEDWDLSDNVGWGPDFAD
                     PSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRYD
                     KYAAAQAWLTDSALIIPTTSKTGRPILSKMVPFTIPFALSGNKGTSDPVLYKYLELQD
                     KAVTADEYQKAQEKWMKEKAESNKKAQEELAKHVK"
     gene            complement(103286..105439)
                     /locus_tag="VUX16_000090"
     CDS             complement(103286..105439)
                     /locus_tag="VUX16_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HET8123154.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     SIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEQETGYNLLTTGMDVYTNVDQEAQKHLWDIYNSDQYVSYPDDDLQVASTVV
                     DVSNGKVIAQLGARHQASNVSFGTNQAVETNRDWGSAMKPITDYAPAIEYGVYDSTAT
                     MVNDIPYNYPGTSTPVYNWDRAYFGNITLQYALQQSRNVTAVETLNKVGLDRAKTFLN
                     GLGIDYPSMHYANAISSNTTESNKQYGASSEKMAAAYAAFANGGIYHKPMYINKVVFS
                     DGSEKEFSDVGTRAMKETTAYMMTEMMKTVLAYGTGRGAYLPWLAQAGKTGTSNYTDD
                     EIEKHIKNTGYVAPDEMFVGYTRKYSMAVWTGYSNRLTPIVGDGFLVAAKVYRSMITY
                     LSEDTHPEDWTMPDGLFRNGEFVFKNGARPIWTEPSTQQSSTAESSTTQASTTVGQQP
                     NNAPATDPNQGQAVQPTQPVQPTPQNPQVQQQPQQ"
     gene            complement(105436..106032)
                     /gene="recU"
                     /locus_tag="VUX16_000091"
     CDS             complement(105436..106032)
                     /gene="recU"
                     /locus_tag="VUX16_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET8123155.1"
                     /translation="MVNYPHKLSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVRVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEAKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLGYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            106099..106626
                     /locus_tag="VUX16_000092"
     CDS             106099..106626
                     /locus_tag="VUX16_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET8123156.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            106696..107037
                     /gene="gpsB"
                     /locus_tag="VUX16_000093"
     CDS             106696..107037
                     /gene="gpsB"
                     /locus_tag="VUX16_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET8123157.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYSKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPQVSSAPSPSHPDPIDVAASSSMTNFDILKRLNRLEKEV
                     FGKQILDNTDL"
     gene            107058..107438
                     /gene="rnpB"
                     /locus_tag="VUX16_000094"
     ncRNA           107058..107438
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VUX16_000094"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            107523..108680
                     /locus_tag="VUX16_000095"
     CDS             107523..108680
                     /locus_tag="VUX16_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET8123158.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWVSDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAVGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            108693..110099
                     /gene="mapZ"
                     /locus_tag="VUX16_000096"
     CDS             108693..110099
                     /gene="mapZ"
                     /locus_tag="VUX16_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET8123159.1"
                     /translation="MSKKRRNRHKKENQESRFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHKDEIEADKFATRQYKKEELVETQSLDDLIQEMREAVEESEASSEEV
                     PSSEDILPPLPLDDEEQGLDSLLLEDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     VLTALALVSVIICVSAYYVYRQVNRSTKEIQTSQSATANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSETSSSSSS
                     QASSNTTSETSPSSSNAASNETRSSRSEVNMGVSSAGVAVQRSASRVAYNQSAIDDSN
                     NSAWDFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNC
                     KTGYFVGNGAGHADDLDY"
     gene            110175..111599
                     /gene="gndA"
                     /locus_tag="VUX16_000097"
     CDS             110175..111599
                     /gene="gndA"
                     /locus_tag="VUX16_000097"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET8123160.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILNRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPADFKFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            111611..112297
                     /locus_tag="VUX16_000098"
     CDS             111611..112297
                     /locus_tag="VUX16_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET8123161.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSVALQ
                     TDYDLILLNAHLGDMTAQDFADKLSRTKPASVIMVLDHREELQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYGSATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQ"
     gene            112398..113360
                     /gene="cbpC"
                     /locus_tag="VUX16_000099"
     CDS             112398..113360
                     /gene="cbpC"
                     /locus_tag="VUX16_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET8123162.1"
                     /translation="MKILKKMMQVLLAVFFFGLLATNTVFANTTGGRFIDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDGGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTINIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWYQDGSTWYYLDPSN
                     GDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            113379..114377
                     /gene="cbpJ"
                     /locus_tag="VUX16_000100"
     CDS             113379..114377
                     /gene="cbpJ"
                     /locus_tag="VUX16_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HET8123163.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(114495..115727)
                     /locus_tag="VUX16_000101"
     CDS             complement(114495..115727)
                     /locus_tag="VUX16_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter permease"
                     /protein_id="HET8123164.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLRILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLASIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(115770..116051)
                     /locus_tag="VUX16_000102"
     CDS             complement(115770..116051)
                     /locus_tag="VUX16_000102"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123165.1"
                     /translation="MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQ
                     NKLLMKKIQQVILACSERDDHGLLMFQGDSGKADLFDFGIGSMGYIGVY"
     gene            complement(116097..116357)
                     /locus_tag="VUX16_000103"
     CDS             complement(116097..116357)
                     /locus_tag="VUX16_000103"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123166.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHEYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNL"
     gene            117257..117586
                     /locus_tag="VUX16_000104"
     CDS             117257..117586
                     /locus_tag="VUX16_000104"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET8123167.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVR"
     gene            117708..118586
                     /gene="mvk"
                     /locus_tag="VUX16_000105"
     CDS             117708..118586
                     /gene="mvk"
                     /locus_tag="VUX16_000105"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET8123168.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLSHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            118568..119521
                     /gene="mvaD"
                     /locus_tag="VUX16_000106"
     CDS             118568..119521
                     /gene="mvaD"
                     /locus_tag="VUX16_000106"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET8123169.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMAFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEYLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            119508..120515
                     /locus_tag="VUX16_000107"
     CDS             119508..120515
                     /locus_tag="VUX16_000107"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET8123170.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDEQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            120499..121509
                     /locus_tag="VUX16_000108"
     CDS             120499..121509
                     /locus_tag="VUX16_000108"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET8123171.1"
                     /translation="MTTNRKDEHIRYALEQKSSYNSFDEVELIHSSLPLYDLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSDKGKEINQKLAQVAETCGILFVTGSYSVALKDSADDS
                     FSVKSSHPNLLLGTNIGLDKSVELGLQTVEEMTPLLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDVKTIERAYELGVRTFDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQDWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELIESYTVEEVIDIVQGWKDDLRLLMCALNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            121586..122284
                     /locus_tag="VUX16_000109"
     CDS             121586..122284
                     /locus_tag="VUX16_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET8123172.1"
                     /translation="MRKFKIFLFIEVCLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVVASILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCKFDDINLFRLMGRDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTAMIGDVEVVRG"
     gene            122281..123276
                     /locus_tag="VUX16_000110"
     CDS             122281..123276
                     /locus_tag="VUX16_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET8123173.1"
                     /translation="MKKQAYVIIALTSFLFVLFFSHSLLDILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGVEELSLRKMQANLKRLLAGQEVVQLADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLSREEEIIEKERKRIARDLHDTVSQELFAAHMILSGVSQ
                     QSLKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLVEGIQVLLKELED
                     KSDLKVSFKQNVTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDLELQLKV
                     VDNGIGFQSGSFDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            123290..123922
                     /locus_tag="VUX16_000111"
     CDS             123290..123922
                     /locus_tag="VUX16_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET8123174.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLTILKEWPEAKILIVSSYLDNEKIMPVLNAGAKGYML
                     KTSSADELLHAVRKVAAGELAIEQEVSKKVEYHRNHMELHEDLTARERDVLQLIAKGY
                     ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGREDF"
     gene            124142..125476
                     /locus_tag="VUX16_000112"
     CDS             124142..125476
                     /locus_tag="VUX16_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HET8123175.1"
                     /translation="MKKTFYKKLGISIIASTLLASQLSTVSALTVISSTGEEYEVSET
                     LQKSPGTNNLSLPEISPTYGQYYTNQSEVIIGKNDLVKVKNTLQYPYSTSAYVKATFK
                     IKNADSVEIGTGRGSASFIKDNVLITAAHVVYDRESKTEATEVEIMPAATPDSNPFGE
                     IKVKEVRYLKEFRNTAPNELTTYDLAVLILEEPIGAQLGTLGLPNNLENTKNLDVTVT
                     GYSAVNKGIKQMYTDTKTILQDTNDFLFYQIDTKGGASGSAVYDSNNRIVGVHTNGSD
                     PEQMNYAVKLNEKALSFIYSVIKGHSIDGWKLISDTWYYYKNSNKQTGWQKINDTWYY
                     LDASGKMLTDWQKVNGKWYYFGSSGSMATSWKYVGGRWYYFDKTNGDMKTGWYKDGST
                     WYYLDPTNGDMKKGWIKVGGNWYYLNSSGAMVTGSQTIDGKVYNFASSGEWI"
     gene            125494..126513
                     /gene="cbpC"
                     /locus_tag="VUX16_000113"
     CDS             125494..126513
                     /gene="cbpC"
                     /locus_tag="VUX16_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET8123176.1"
                     /translation="MKILKKTMQVGLTVFFFGLLATSTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDKGEMVVGWQYIEIPGTGYRDNLLDNQPVNEIALQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYTPSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     QTGWQYLGNNWYYLRSSGAMATGWVKDGSTWYYLDAQNGDMKTGWAYVGNSWYYLRSS
                     GAMSTGWVKDGSTWYYLNASNGDMKTGWFQVNGKWYYAYSSGALAVNTTVGGYYVNYN
                     GEWIK"
     gene            126831..128114
                     /locus_tag="VUX16_000114"
     CDS             126831..128114
                     /locus_tag="VUX16_000114"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET8123177.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFNSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDDVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGDTVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLAELKEKYRKEL
                     AAAKEEAYKDAVEGAAIDKAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQSLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(128162..130528)
                     /locus_tag="VUX16_000115"
     CDS             complement(128162..130528)
                     /locus_tag="VUX16_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET8123178.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQINRYERAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGDNTIDEILQHPEKLEDIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLIHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSQDLETIQKHIATIEEELGIEYDS
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRSGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHFRKGDKVIHLVNDAEINVFNGDLGVI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLIEN
                     VEEKQQAVSETATSSTSEQSYTLTEENWDSIPAMIGITDADLKEIFGK"
     gene            complement(130808..131422)
                     /gene="lepB"
                     /locus_tag="VUX16_000116"
     CDS             complement(130808..131422)
                     /gene="lepB"
                     /locus_tag="VUX16_000116"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET8123179.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQSFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            complement(131426..132307)
                     /locus_tag="VUX16_000117"
     CDS             complement(131426..132307)
                     /locus_tag="VUX16_000117"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET8123180.1"
                     /translation="MASITLTPSEKEIQSFLEHYQTSLAPSKNPYIRYFLRLPQATVS
                     IYTSGKVLLQGEGAEKYARFFGYQIVEENSDQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEIIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSIIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            132394..132696
                     /gene="zapA"
                     /locus_tag="VUX16_000118"
     CDS             132394..132696
                     /gene="zapA"
                     /locus_tag="VUX16_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET8123181.1"
                     /translation="MANLNRFKFTFGKKTLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            132693..133241
                     /locus_tag="VUX16_000119"
     CDS             132693..133241
                     /locus_tag="VUX16_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET8123182.1"
                     /translation="MISLLLLLVLAWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANPQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLLPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAAIQNPLEKSIVAKH
                     IIQSIPVTTSWLKQIWVTNLIG"
     gene            133460..135796
                     /locus_tag="VUX16_000120"
     CDS             133460..135796
                     /locus_tag="VUX16_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET8123183.1"
                     /translation="MNKKILETLEFNKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRGVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGVFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLASEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDDRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKHVNVVKRTSGRGPQARLDLRGKRYEEAMNELDAFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     regulatory      135960..136048
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            136139..137461
                     /locus_tag="VUX16_000121"
     CDS             136139..137461
                     /locus_tag="VUX16_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET8123184.1"
                     /translation="MLELLKSIDAFVWGPPLLILLLGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDQGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPATIALVFTSAFSPLAVVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     gene            137679..138227
                     /locus_tag="VUX16_000122"
     CDS             137679..138227
                     /locus_tag="VUX16_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET8123185.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKANNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLT
                     ILCNYANNLANTPINPELQPYA"
     gene            138337..139236
                     /locus_tag="VUX16_000123"
     CDS             138337..139236
                     /locus_tag="VUX16_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET8123186.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIADFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLTE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(139261..140535)
                     /gene="serS"
                     /locus_tag="VUX16_000124"
     CDS             complement(139261..140535)
                     /gene="serS"
                     /locus_tag="VUX16_000124"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET8123187.1"
                     /translation="MLDIKRIRTDFETVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQTRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(140749..141120)
                     /locus_tag="VUX16_000125"
     CDS             complement(140749..141120)
                     /locus_tag="VUX16_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET8123188.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            complement(141123..142487)
                     /locus_tag="VUX16_000126"
     CDS             complement(141123..142487)
                     /locus_tag="VUX16_000126"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET8123189.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIMVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSRIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
BASE COUNT        42679 a        26139 c        31856 g        41994 t
ORIGIN      
        1 agtttatcgt ttttcttttt agttgattgc acatttgtgc ttatataaac aaaaatagtt
       61 tatctgttgt ttttggactg acaactttat tatgtagttg tattctatag ttacaaaaga
      121 aaattttaaa atttcaaatg aaaaaagctt tttacatagt gaaatgagga ggaatttatg
      181 gaaattattg ttccagatca aattatcatg ggtttaattt tatatgctgg tgatgcgaaa
      241 caacatattt ataaagcgtt agattacata aaaaatggta catgtgaacg gtgtgaagaa
      301 gaaatccagt tagctgatgc cgccttatta gaagcccata atctacaaac aaaattcttg
      361 gcacaagaag cgtctggtac aaagacagaa attacagctc tctttgttca ttcacaagat
      421 catctcatga ctagtatgac ggagattaat ttaatcaaag aaattattag tttgagaaaa
      481 gaacttcata aaaaataata ctagagtatt atcattgtta ttaacataga ggaggaaaac
      541 ataatggtga agattggttt gttttgtgca gcaggttttt ctactggtat gcttgtaaat
      601 aatatgaaaa ttgcagcgca atctagtgga gttgaggcag aaatagaggc gttttctcag
      661 tctaaattag cggattatgc gccaaatata gatgttgcac tattgggtcc acaagttgct
      721 tatacattag ataaatcaaa agaaatttgt gataagtgtg atgttccgat agctgttatt
      781 ccgatgatgg actatggtat gttagatggg aaaaaagtat tagatttggc cctatctttg
      841 attagtgggt aagaaaagga gatttattat ggcaaagatg gatgttcaga aaatcattgc
      901 accgatgatg aagtttgtga atatgcgtgg cattatagct ctaaaagatg ggatgttagc
      961 aattttgcca ttgacagtag ttggtagttt attcttgatt atgggacaat tgccgttcga
     1021 aggattaaat aagagcattg ctagtgtttt tggagctaat tggacagagc cgtttatgca
     1081 agtatattca ggaacttttg ctattatggg tctaatttct tgtttttcaa ttgcctattc
     1141 ttatgctaag aatagcggag tagaggcttt accagctgga gttctatctg tatctgcatt
     1201 ctttattttg ctaagatcat cttatatccc taaacaaggt gaggcgattg gggacgctat
     1261 tagtaaagtt tggtttggag gccagggaat tatcggtgct atcattatag gtttggtagt
     1321 aggaagtatt tataccttct ttataaagag aaaaattgtt attaagatgc cagaacaagt
     1381 tccacaagct attgccaaac agtttgaaac aatgattcca gcatttgtaa ttttcttatc
     1441 ttctatgatt gtatatattt tagcgagctc attgactaat ggcgggacat tcatagaaat
     1501 gatttattct gctattcaag ttccgttgca aggtttaact ggatctttgt atggtgctat
     1561 tggaattgca ttctttatat catttttgtg gtggtttggt gttcatgggc aatcggtagt
     1621 aaatggagta gtgacagctc ttcttttatc taatcttgat gctaataaag ctatgttagc
     1681 ctctgctaat ctatcattag aaaatggagc acatattgtt actcaacagt ttttagattc
     1741 atttttaatt ctatcaggtt cagggattac gtttggtctt gtagttgcca tgctttttgc
     1801 agcaaaatca aaacaatacc aagccttagg aaaagttgca gcttttccag caatatttaa
     1861 cgtaaatgag ccagttgtat ttggatttcc gattgtcatg aatccagtta tgtttgtacc
     1921 tttcattctt gttcctgtac ttgcagctgc gatagtatat ggatctattg caacaggttt
     1981 catgcagcca ttctcagggg taacattgcc ttggagtaca ccagctattc tatcaggatt
     2041 cttggtgggt ggatggcaag gagttattac tcagctggtg atattagcga tgtctacatt
     2101 ggtttacttt ccattcttta agatacagga tcgtttagct taccaaaatg aaatcaaata
     2161 atcttagagg tatttgtgtg ttactgttaa actcatacat ttgtgctaaa aattagagag
     2221 ttaaaatttt tctagttaaa agcttgaaaa tttttataaa aatcggtatt atattttcga
     2281 aagaaataaa aatattttcg aaagaaaggt gcttacgatg gtaaatacag aagtagcaag
     2341 aacaacaatc aagacagaat attttggcag ccttactgaa aggatgaaca aatatcgaga
     2401 agatgtctta aataaaaaac cttatattga tgctgagaga gcagttctag caacacgcgc
     2461 ctatgaacga tacaaggaac aacctaatgt cctaaaacgt gcatatatgc tgaaagaaat
     2521 tttggaaaat atgtctatct atattgaaga agaatctatg attgcgggaa atcaagcttc
     2581 ttccaataaa gatgctccta tttttccgga atatacgcta gaatttgttc tcaatgagtt
     2641 ggagcttttt gaaaagcgtg atggagatgt tttctatatt acagaagaaa caaaagaaca
     2701 acttagaagt attgctccgt tttgggaaaa taataattta cgtgctagag ctggtgcctt
     2761 attacctgaa gaagtgtctg tttatatgga aacaggattc ttcggtatgg aaggtaagat
     2821 gaattctgga gatgctcact tagcagttaa ctatcagaaa cttttgcaat ttggtttaag
     2881 aggttttgaa gagcgggctc gtaaagcaaa agtagctcta gatttaacag attcagcaag
     2941 tattgataaa tatcattttt acgactctat atttatcgta atcgatgcta ttaaagtata
     3001 tgcaaagcgc tttgttgctc ttgctaaaag tttagccgaa aatgcaaatc ctaaacgtaa
     3061 gaaagaatta cttgagattg cagatatttg ctctagagtc ccatatgaac cggcaactac
     3121 ttttgcagaa gctattcaat cagtttggtt tattcaatgt attttacaaa ttgaatctaa
     3181 tggccactct ctttcatatg gccgttttga tcaatatatg tatccatata tgaaggctga
     3241 tttagaaagt ggtaaagaaa cagaagatag cattgttgaa cgtctgacaa atctttggat
     3301 taagacaatt acaatcaata aggttcgcag tcaatcacat acattttctt cagcaggaag
     3361 tcctttatat caaaatgtta caattggtgg acagactcga gataagaagg atgctgttaa
     3421 cccattatct tatttggtat taaaatcagt tgcacaaacc catctaccgc aacctaatct
     3481 aactgtacgt taccatgcag gtttagatgc tcgtttcatg aatgagtgta ttgaagtgat
     3541 gaaacttggt tttggtatgc ctgcatttaa taatgatgag attattattc cttcttttat
     3601 tgcaaaagga gtattggaag atgatgctta tgattacagt gccattggat gtgttgaaac
     3661 ggcagttcca gggaaatggg gctatcgttg cacaggtatg agttatatga acttccctaa
     3721 ggttctactt atcacgatga atgatggaat tgatccggct tcgggtaaac ggtttgcacc
     3781 aagctttggt cattttaagg atatgaagaa cttttctgaa ttagaaaatg cttgggataa
     3841 aacactaaga tatttgacac gaatgagtgt tattgttgaa aattctattg atttatcatt
     3901 ggaacgagaa gttcctgata ttctatgttc agcattgact gatgattgta ttggtcgtgg
     3961 aaaacacctt aaagaaggtg gagcagtata tgattatata tcaggattgc aagttggaat
     4021 tgcaaatttg tcggattcat tagctgcaat taaaaaattg gtgtttgagg aagaacgtat
     4081 aagcccaagt cagctttggc atgcactgga aacagattat gccggagaag aaggtaaggt
     4141 cattcaagaa atgttgattc atgatgcacc taagtatggt aatgatgatg attatgctga
     4201 caaattggtt actgctgctt atgacattta tgttgatgaa attgctaaat atcctaatac
     4261 acgttatgga agagggccta ttggaggaat tcgttattca ggaacatctt ctatatcagc
     4321 caacgtaggg cagggacgtg gaacattagc aactccagat ggacgcaacg cgggtacacc
     4381 gttagcagag ggttgttcac catcacataa tatggatcaa cacggcccta catctgtttt
     4441 aaaatctgtt tcaaaattac caacagatga aatcgtaggt ggggttctct taaatcagaa
     4501 agtaaatcct caaacgttag ccaaagaaga agataaatta aaactaattg ctttgttacg
     4561 aacattcttt aatcgtttac atgggtacca tattcaatac aatgttgttt ccagagagac
     4621 gttgattgac gctcagaaac atcctgaaaa acacagagac ttaattgttc gtgttgcagg
     4681 atactctgca ttcttcaatg ttctttctaa ggcaacccaa gatgacatta taggacgtac
     4741 tgagcatact ttgtaaaata aagaggttct ttttatggaa tttatgcttg acacattaaa
     4801 tttagatgag attaaaaagt ggtctgaaat tttgccgcta gctggggtaa cttcaaatcc
     4861 cactattgca aaaagagagg gttctattaa tttttttgaa cgaatcaaag atgtaagaga
     4921 attgattggc tctacaccct ctattcatgt tcaggtgatt tctcaagatt ttgaaggcat
     4981 cttaaaggat gctcatgaaa ttcgaagaca agcaggagat gatatattta tcaaagtacc
     5041 tgttactcca gctggattac gtgcaataaa ggtgctaaaa aaagagggct accatatcac
     5101 tgcaacagct atttatacag ttattcaggg attattagct atcgaagtag gagcggatta
     5161 cctagctcca tattataata gaatggaaaa tctgaacatt gattcaaatt ctgtcattcg
     5221 tcaattagct cttgctattg atagacagaa ctctcctagt aagattttag ctgcatcctt
     5281 taaaaatgta gcacaagtaa ataatgcttt agctgcaggt gcgcatgctg ttacagcagg
     5341 agcagatgtt tttgaatcag ctttcgccat gccatctatc caaaaggcgg ttgatgactt
     5401 ttctgacgac tggtttgtta ttcaaaatag tcgttccatt tagatagaga ggaaatacat
     5461 atgagaattt ttgctagtcc ttctagatat attcaggggg aaaatgcctt gtttgaaaat
     5521 gccaaatcaa ttttggattt gggaaattgc cctattctat tatgcgatca gttggtttat
     5581 gatattgttg gaaaacgatt tgaagattac ctacataggt atggtttcca tattgttctg
     5641 gcgctattta atggtgaagc ttctgacaat gaaatcaatc gagttgttgc cttggctgag
     5701 aaagaaaatt gtgatagtat tatcggtctt ggtgggggaa agacgattga tagcgcaaaa
     5761 gctattgcag atttgattga aaagcctgtt attattgctc caacaattgc atcgaccgac
     5821 gcacctgtat ctgctttatc tgttatttat acagatgaag gtgcatttga tcattatcta
     5881 ttttattcta aaaatccaga tttagttttg gttgatacaa aagttatttc acaagcccct
     5941 aagcgtttat tagcgtctgg tattgcagat ggtttagcaa cttgggttga ggcgcgtgcg
     6001 gttatgcagg caaatggaaa aactatgttg ggacaacagc aaacattggc tggagttgca
     6061 attgcgaaga aatgtgaaga aacgctgttt gcagatggtt tacaggctat ggcagcttgt
     6121 gaagctaaag tggtgacacc agcattagaa aatattgttg aagctaatac tttattgagt
     6181 ggcctaggtt ttgaaagtgg aggattagct gcggcgcatg caattcataa tggttttact
     6241 gcattgacag gtgacattca tcatttaaca catggtgaaa aagtagctta tggaacttta
     6301 gtacaactat tattggaaaa tagacctaaa gaagaacttg ataagtatat tgagttttac
     6361 aaaaaaattg gtatgccaac aactctaaaa gaaatgcatt tggatcaagt tggatatgat
     6421 gatttaataa aagttggtaa acaagcaact atggagggtg agacaattca tcagatgccg
     6481 tttaagattt cgccttcaga tgttgctcaa gctattatcg ctgtagatgc ctatgtaaat
     6541 tcaaaataaa caataaggac tactgttttc caaatgatag tcttttattg atcctcgtat
     6601 tgaattctat agcagattga aataagatga gaacaaatcg attgggaaag taaaattaat
     6661 ttctaacaat gttttagcaa ttgtttcgta ctatttcaga ttcagtccac tatacgttct
     6721 tcataaatca aaaagcgaca taggttgtcg gctatttatt gtgaatacat taattagcat
     6781 tccagtttta tcttcggtct aaaataagta ttttgtgcta tacgagataa gcgtcttgac
     6841 ttactccttg atttactgca taacaatggg ataaaaagtg ggagatagag caattcatag
     6901 tcatcaaaat taatgagata cagtatacag tttttccttt aaacacattt caaattccct
     6961 caaaaatggt ataatagtaa catcacaaaa ttggagagag accatgagtt tttacaatca
     7021 taaagaaatt gagcctaagt ggcagggcta ctgggcagaa catcatacat ttaagacagg
     7081 aacagatgca tcaaaaccta agttttatgc gcttgatatg ttcccttatc cgtctggagc
     7141 tggtctgcac gtaggacacc cagaaggtta tactgcaacc gatatcctca gtcgttacaa
     7201 acgtgcgcaa ggctacaatg tccttcaccc aatgggttgg gatgcttttg gtttgcctgc
     7261 agagcaatac gctatggata ctggtaatga cccagcagaa tttacagcgg aaaacattgc
     7321 caacttcaaa cgtcaaatca atgcgcttgg attttcttat gactgggatc gtgaagttaa
     7381 cacaacagat ccaaactact acaagtggac gcaatggatt ttcaccaagc tttacgaaaa
     7441 aggcttggcc tatgaagctg aagtgccagt aaactgggtt gaggaattgg gaactgccat
     7501 tgccaatgaa gaagtgcttc ctgacggaac ttctgaacgt ggaggctatc cagttgtccg
     7561 caaaccaatg cgccaatgga tgctcaaaat cacggcttac gcagagcgct tgctcaatga
     7621 cttagatgaa ctagattggt cagagtctat caaggatatg caacgcaact ggattggtaa
     7681 atcaactggt gccaatgtaa ctttcaaagt aaaaggaaca gacaaggaat ttacagtctt
     7741 tactactcgt ccggacacac ttttcggtgc gactttcact gttttggctc ctgaacatga
     7801 attagtagat gccatcacaa gcacagagca agcagaagca gtagcagact acaaacacca
     7861 agccagcctt aagtcagact tggctcgtac cgaccttgcc aaagaaaaaa ctggtgtatg
     7921 gactggtgct tatgccatca atcctgtcaa tggtaaggaa attccaatct ggattgcgga
     7981 ttacgttctt gctagctatg gtacaggtgc ggtaatggct gtgcctgccc acgatcaacg
     8041 tgactgggaa tttgccaaac aatttgacct tccaatcgtc gaagtacttg aaggtggaaa
     8101 tgttgaagaa gctgcctaca cagaagatgg ccttcacgtt aattcagact tcctagatgg
     8161 actcaacaaa gaagacgcta ttgccaagat tgtggcttgg ttggaagaaa aaggctgtgg
     8221 acaagagaag gtaacctacc gtctccgcga ctggctcttt agccgtcaac gttactgggg
     8281 tgagccaatc ccaatcattc attgggaaga tggaacttca acagctgtcc ctgaaagtga
     8341 attgccactt gtcttgcctg taaccaagga tatccgtccc tcaggtactg gtgaaagtcc
     8401 actagctaac ttgacagact ggcttgaagt gactcgtgaa gatggtgtca aaggtcgtcg
     8461 tgaaacaaat actatgccac aatgggcagg ttcaagctgg tactacctcc gctatattga
     8521 cccacacaat actgagaaat tggctgacga ggatctgctc aaacaatggt tgccagtaga
     8581 tatctacgtg ggtggtgcgg aacatgctgt acttcacttg ctttacgctc gtttctggca
     8641 taaattcctc tatgacctcg gtgttgttcc aactaaggaa ccattccaaa aactctttaa
     8701 ccaaggaatg attttgggaa caagctatcg tgaccaccgt ggggctcttg tggcgactga
     8761 caaggttgaa aaacgtgatg gttctttctt ccatgtggaa acaggggaag agttggagca
     8821 agcgccagcc aagatgtcta aatcgctcaa gaacgttgtc aacccagacg atgtggtgga
     8881 acaatacggt gctgataccc ttcgtgtcta tgaaatgttc atgggaccac tcgatgcttc
     8941 gattgcttgg tcagaagaag gtctggaagg aagtcgtaag ttccttgacc gtgtttaccg
     9001 tttgattaga agtaaggaaa ttgttgcgga aaacaatggc gctcttgaca aggtttacaa
     9061 cgaaactgtt aaagctgtca cagagcaaat tgattccctc aaattcaaca cagccattgc
     9121 ccaacttatg gtctttgtca atgcggctaa caaggaagac aagctctatg ttgactatgc
     9181 caaaggattt atccaattga ctgccccatt tgcacctcac ttggcagaag aactctggca
     9241 aactgttgct gcaacaggtg agtcaatctc ttacgtgact tggccaacat gggacgaaag
     9301 taaactgatt gaagacgaaa tcgaaatcgt tgtccaaatc aaaggtaaag tccgtgccaa
     9361 actcatggtc gctaaagacc tatcacgtga agaattgcaa gaaattgctc tagcggatga
     9421 aaaagtcaaa gcagaaattg acggtaagga aatcgtgaaa gtgattagtg taccaaataa
     9481 attggttaat attgttgtaa aataaccaat ttatttgctg atttccaacc tcaaacagtt
     9541 tcctaaactg tttgagccaa ctaaactcgt taatatcgtt gtgaaataag gtaggaatcc
     9601 ttcagagtag aatctggagg attttttgaa tcttcttatg aaagtatggt atactatggg
     9661 caactataaa gtttgaaaag tgaaaaaagg agaaagctat gccagtaaat gaatatggtc
     9721 aaatgattgg ggagtcaatg gaaggttata caccaggtga actgccttct attgatttct
     9781 tagaagggcg ttatgctagg atagaggctc tttcagtgga aaagcatgcg gaggatttgc
     9841 tagctgttta tgggcctgat acgcctcagg agatgtggac ctaccttttt caggagccag
     9901 tagcagatat gggggagctg gttagccttt tacatcagat gttggctcgt aaggaccgtt
     9961 tttactatgc aatcatagac aaggcgactg gtaaggcttt gggatctttt tctctcatgc
    10021 gcattgacca gaataaccga gtaatagaag tcggagcagt cactttttct ccagagctaa
    10081 ggggtacacg gataggaact gaagctcagt atctcctagc tcgctatgtt tttgaggagc
    10141 taaactatcg tcgctacgag tggaaatgcg atgccttaaa tctgccatcc agacgagctg
    10201 cggagcgttt gagctttatt tatgaaggaa ccttccgtca ggcagtggtt tataagggac
    10261 gtacgagaga tacggattgg ttgtctatga ttgataagga ctggcctcaa gtcaaagatc
    10321 gtttggaaac atggttgcgt cctgaaaatt ttgataaaaa tggacagcag tacaagagct
    10381 tgagagaact ttaagaggtg ttgagatgat tactattaaa aagcaagaaa ttgtcaagct
    10441 agaggatgtt ttacatctct atcaggctgt cggttggaca aattataccc atcaaccaga
    10501 gatgctggag caggccttat ctcattcatt agtaatttat ctggcacttg atggtgatgc
    10561 tgtggtgggc ttgattcgtt tggttggaga tggattctca tcagtattgg ttcaggattt
    10621 aatcgtttta ccaatctatc agcgtcaagg aattggtagt gccttgatga aagaggcttt
    10681 agaggattac aaagatgcct atcaagtcca gctggtgaca gaagagacag aaagaacctt
    10741 gggcttctat cgttctatgg gctttgaaat cttatccacc tataattgta tagggatgac
    10801 ttggatgaat cgtaaaaaat aacaaaactt gttttttctt aagcaaaatt taaggatggt
    10861 ctagtattat atagtcatta aataaagacc tcctaacttt atttaataaa atccaaaagt
    10921 ttttttcatc ataatctcct aatgaagtca cccaatcagg tgactttttg tggggtgagg
    10981 tgatggtaat agaaattttt tgaaaaatgg tagaatttga gaaaagttaa gctagtttta
    11041 agctttgtct tgtatcatat agttattaaa taaagacctc ctaactttat ttaataaaat
    11101 cctaaacttt tctttttcat aataatctcc cttaactcca cccaatcagg tggagttttt
    11161 tggctttatt tcaggctttt ggggactatt ctaaaaatca tttttcgata ttttttggta
    11221 tttttcggat tttggtcggg gaattggcgg gaactttttt agaaaatatg actaagaaat
    11281 aggtttgttg ttacttcagc tacttcaaac tcaatttgat tgtaagtgac tgttaattga
    11341 aggactgaaa ctgctgtaat aatgattttg cttgtccagt agtggcgtat taaatgagga
    11401 gtgacatata agattgtctc ttcgtttact aaatcaaaat ttctatgaaa ttgatagaat
    11461 ccctaatttt ctcttaaact tgaaagtctt gttgtaaagc ggttaaagct tgagaagctg
    11521 aggatgtaaa gttttgacaa attttgtgaa ctgtgggata atggagagga attaaggatt
    11581 agttctatat catggactag aaaagacccc aagctaactt ccacattaag ctcggggtct
    11641 tttttgacac tatctatctt tgtttagcca tttatcgact aagcgaagaa caacaccgac
    11701 cacaattggt ccgatgatag ttttaaggat tagttccatc atgggctatc tcacctcctt
    11761 tcgtaggcgg tgtagcagtg ccgtagaata ttataccaca taagtattaa actcgggagg
    11821 cacccaatca ggtggagttt ttttgctcta tttcaggctt ttggggacta ttttaaacat
    11881 cattttccga taacttttgc ttaatcttat aaattttatt ggacagattc taaagttgga
    11941 gaagctgaat tgatgaagat ataaaccttt gacaaatttt gtgaactatg ggataataaa
    12001 agggaattaa gtattgtgtc tatatcatag gctagaaaag accccaagct cacgaccaaa
    12061 taagcttggg gtctttttga cactatttgt ccttgtttag ccatttatcg actaatcgaa
    12121 gaacgacacc gaccacaatt ggtccgatga tagttttaag tattgtatcc atcatgggct
    12181 aattcacctc ctttcgtagg cggtgtagaa gtgccgaaca atattatacc acataagtgt
    12241 taaagtcgga attcacccaa tcaggtggag ttttttggct ctattttagg cttttgggga
    12301 ctattctaaa aatcattttt cgatattttt cggattttgg tcggggaatt ggcggggatg
    12361 aaaatgtaaa actttgacaa aatttgtgaa ctatgggata ataaaaagga attgagtact
    12421 agttctatat catggactag aaaagacccc aagctcacga ccaaataagc ttggggtctt
    12481 tttttgacac tatttgtcct tgtttagcca tttatcgact aatcgaagaa cgacaccgac
    12541 cacaaatggt ccgatgatag ttttgagtac taattccatc atgggctatc tcacctcctt
    12601 tcgtaggcgg tgtagcagtg ccgtatgata ttataccaca taagtgctaa actcaggagt
    12661 tacccaatcg ggtggctttt tgtttgtggc ttggattttt gatataatag agccatgagt
    12721 agaattttag acaatgagat aataggggac gaggagttag tagaacgcac gctccgtcct
    12781 cagtacttac gtgaatatat tgggcaggac aaggtcaagg accagctaca aatctttatt
    12841 gaggctgcca aaatgcggga tgaagcgctg gatcatgtgc tcttatttgg gcctccaggc
    12901 ttgggaaaaa cgaccatggc ctttgttatt gccaacgaac taggtgtaaa tctaaagcag
    12961 acctctgggc ctgtcattga aaaagccggt gatctggtag caattttgaa tgatttagag
    13021 cctggggatg tcctttttat tgatgagatt catcgcttgc caatgtcagt ggaagaggtg
    13081 ctttatagtg ctatggagga cttctacata gatattatga ttggggctgg tgagggtagt
    13141 cgtagtgttc atttggagtt accacctttt accttgattg gtgcgacgac tcgggctggt
    13201 atgctctcaa atccactacg ggcacgtttt gggattacag gccatatgga gtattatgcc
    13261 catgctgact tgacagaaat tgtcgagcgg acggcagata tttttgagat ggaaatcact
    13321 catgaggcag catctgagtt ggccctacgt agtcgtggga cccctcgtat tgccaatcgt
    13381 ctcctcaagc gcgtgcgcga ttttgcccag ataatgggga atggggttat cgatgatgtt
    13441 attaccgata aggctttgac tatgctggat gttgaccacg aaggtttgga ctatgtggat
    13501 caaaaaatcc ttcgcaccat gattgagatg tacggtggtg gccctgtcgg attaggaact
    13561 ctttctgtca atattgccga ggagcgtgag actgtagaag acatgtatga gccttacttg
    13621 attcaaaaag gttttatcat gcggacacgg tctggacgga tggcgactgc taaggcatat
    13681 gagcatttgg ggtatgagta caatgaaaaa taagcaagaa attctagagt cttttagaaa
    13741 aaatccagat atgatggcta ttctgactat catccaaaac ctggagttga cagattcctg
    13801 gttggcagca ggttctgtca gaaatttcat ctggaatctc ttgtcagaca aatcaccttt
    13861 tgactttgaa acagatgtag atgtgatttt ctttgatccg gatatttctt atgaggaaac
    13921 cttattactg gagaaaaaac tgcgagagga ctttcctcag taccagtggg aattgaaaaa
    13981 tcaagtctat atgcaccagc acagccctca tactgctccc tataccagtt cccgtgatgc
    14041 tatgagtaag tatccagaac gatgtacggc tgttggactg cgcttgaatg aagaacctgc
    14101 tttggaactc tttactccat acggtctgga ggatattttg aattttcaag ttcgtccaac
    14161 tcctcatttt ttagagaatc aagaacgaat ggaactctat caaacacgtt tatccaagaa
    14221 aaattggcag gagaaatgga aaaatttgat ttttaaaaat acttaaggaa actttaagct
    14281 agggagtgta cactaagttc ataagttaag aagaccttaa cttaaactcc taaaactttt
    14341 tcataataat ctccctataa aaataaagtc gcccaatcag gcggcttatt tttttgaaaa
    14401 atgggcttgg tgcctgagaa taaatagctt agtgatagaa gaaaatgggg aaatatggta
    14461 taatgaaacg atagattttt gaataggaat aagatcatgt ttggattttt taagaaagat
    14521 aaggctgtgg aagtagaggt tccgacacag gttcctgctc atatcggcat catcatggat
    14581 ggcaatggcc gttgggctaa aaaacgtatg caaccgcgag tttttggaca taaggcgggc
    14641 atggaagcat tgcaaaccgt gaccaaggca gccaacaaac tgggcgtcaa ggttattacg
    14701 gtctatgctt tttctacgga aaactggacc cgtccagatc aggaagtcaa gtttatcatg
    14761 aacttgccag tagagtttta tgataattat gttccggaac tacatgcgaa taatgttaag
    14821 attcaaatga ttggggagac agaccgcctg cctaagcaaa cctttgaagc tttaaccaag
    14881 gctgaggaat tgactaagaa caacacagga ttgattctta attttgctct taactatggt
    14941 ggacgtgctg agattacaca ggcgcttaag ttgatttccc aggatgtttt agatgccaaa
    15001 atcaacccag gtgacatcac agaggaattg attggcaact atctctttac ccagcatttg
    15061 cctaaggact tacgagaccc agacttgatt atccgtacta gtggagaatt acgtttgagc
    15121 aatttccttc catggcaggg agcctatagt gagctttatt ttacggacac cttatggcct
    15181 gattttgacg aagtggcctt gcaggaagct attcttgcct ataatcgtcg tcatcgccga
    15241 tttggaggag tttaggagga aatatgaccc aggatttaca gaaaagaacc ttgtttgcag
    15301 ggattgccct ggctattttc ctaccaattt taatgattgg gggcctcttg cttcagatag
    15361 caatcggaat catagccatg ctagccatgc atgaactttt gaagatgaga ggtctagaga
    15421 ccatgacgat ggagggcctc ttgaccctct ttgcaacctt tgcattgacc attcccttgg
    15481 agaattacct gacttttttg ccagttgatg ggaatgtggt tgcctatagt gttttgattt
    15541 caatcatgtt aggaacgacc gtttttagca agtcttatac gattgaggat gcggttttcc
    15601 ctcttgctat gagcttctac gtgggctttg gatttaatgc tttactagat gctcgtgttg
    15661 caggtttgga caaggctctc ttagccttgt gtatcgtctg ggcgacagac agtggtgcct
    15721 atcttgttgg gatgaactat gggaaacgaa agttagcacc aagggtatcg cctaataaaa
    15781 cccttgaggg tgccttgggt ggtattttag gagcaatttt agtaaccatt atctttatga
    15841 tagttgacag tacagttgct cttccatatg gaatttacaa gatgtcagtc tttgctattt
    15901 tctttagcat tgctggacaa tttggtgatt tactagaaag ttcgatcaaa cgtcattttg
    15961 gtgttaagga ttctgggaaa tttatccctg gacatggtgg tgttttggat cgtttcgata
    16021 gtatgttgct tgtatttcca atcatgcact tatttggact cttttaatca aaagacggag
    16081 gaaacgctat gctcggaatt ttaaccttta ttctggtttt cgggattatt gtagtggtgc
    16141 acgagttcgg gcacttctac tttgccaaga aatcagggat tttagtacgt gaatttgcca
    16201 tcggtatggg acctaaaatt tttgctcaca ttggcaagga tggaacggcc tataccattc
    16261 gaatcttgcc tctgggtggc tatgtccgca tggccggttg gggtgatgat acaactgaaa
    16321 tcaagacagg aacgcctgtt agtttgacac ttgctgatga tggtaaggtt aaacgcatca
    16381 atctctcagg taaaaaattg gatcaaacag ccctccctat gcaggtgacc cagtttgatt
    16441 ttgaagacaa gctctttatc aaaggattgg ttctggaaga agaaaaaaca tttgcagtgg
    16501 atcacgatgc aacggttgtg gaagcagatg gtactgaggt tcggattgca cctttagatg
    16561 ttcaatatca aaatgcgact atctggggca aactgattac caattttgca ggtcctatga
    16621 acaattttat cttaggtgtc gttgtttttt gggttttaat ctttatgcag ggtggtgtca
    16681 gagatgttga taccaatcag ttccatatca tgccccaagg tgccttggcc aaggtaggag
    16741 taccagaaac ggcacaaatt accaagattg gctcacatga ggttagcaac tgggaaagct
    16801 tgatccaagc tgtggaaaca gaaaccaaag ataagacggc accgactttg gatgtgacta
    16861 tttctgaaaa ggggagtgac aaacaagtca ctgttacacc cgaagatagt caaggtcgtt
    16921 accttctagg tgttcaaccg ggggttaagt cagattttct atccatgttt gtaggtggtt
    16981 ttacaactgc tgctgactca gctctccgaa ttctctcagc tctgaaaaat ctgattttcc
    17041 aaccagattt gaacaagttg ggtggacctg ttgctatctt taaggcaagt agtgatgctg
    17101 ctaaaaatgg aattgaaaat atcttgtact tcttggcaat gatttccatc aatattggga
    17161 tttttaatct tattccgatt ccagccttgg atggtggtaa gattgtgctc aatatcctag
    17221 aagccatccg ccgcaaacca ttgaaacaag aaattgaaac ctatgtcacc ttggccggag
    17281 tggtcatcat ggttgtcttg atgattgctg tgacttggaa tgacattatg cgactctttt
    17341 ttagataatc gaggaatatt atgaaacaaa gtaaaatgcc tatcccaacg cttcgcgaaa
    17401 tgccaagcga tgctcaagtt atcagccatg ctcttatgtt gcgtgctggt tatgttcgcc
    17461 aagtttcagc aggtgtttat tcttatctac cacttgccaa tcgtgtgatt gaaaaagcta
    17521 aaaacatcat gcgccaagaa ttcgaaaaga ttggtgctgt tgagatgctg gctccagccc
    17581 ttcttagtgc agaattgtgg cgtgaatcag gtcgttacga aacctatggt gaagaccttt
    17641 acaaactaaa aaaccgtgaa aaatcagact ttatcttagg tccaactcac gaagaaacct
    17701 ttacagctat tgtccgtgat tctgttaaat cttacaagca attgccactc aacctttatc
    17761 aaattcagcc caagtatcgt gatgaaaaac gcccacgtaa tggacttctt cgtacacgtg
    17821 agtttatcat gaaggatgct tatagtttcc acgctaacta tgatagtttg gatagtgttt
    17881 atgatgagta caaagcagcc tatgagcgta ttttcactcg tagtggttta gacttcaagg
    17941 ctattattgg tgacggtgga gccatgggtg gtaaggatag ccaagaattt atggccatta
    18001 catctgctcg tacagacctt gaccgctggg ttgtcttgga caagtcagtt gcctcatttg
    18061 acgaaattcc tgcagaagtg caagaagaaa tcaaggcaga attgctcaaa tggatagtct
    18121 ctggtgaaga taccattgct tactcaagtg agtctagcta tgcagctaac ttagaaatgg
    18181 caacaaacga gtacaaacca agcaaccgtg ttgtcgctga agaagaagtt actcgcgttg
    18241 caacgccaga tgttaaatca attgatgaag ttgcagcttt cctcaatgtt ccagaagaac
    18301 aaacgattaa aaccctcttc tacattgcag atggtgagct tgttgcagcc cttctagttg
    18361 gaaatgacca actcaacgaa gtcaagttga aaaaccactt gggagcagat ttctttgacg
    18421 ttgctagcga agaagaagtg gcgaatgttg ttcaagcagg atttggttca cttggaccag
    18481 ttggtttgcc agagaatatt aaaattattg cagatcgtaa ggtgcaagat gttcgcaatg
    18541 cagttgtcgg tgctaacgaa gatggctacc acttgacggg tgtgaaccca ggccgtgatt
    18601 ttactgcaga atatgtggat atccgtgaag ttcgtgaggg tgaaatttcc ccagatggac
    18661 aaggtgtcct taactttgcg cgtggtattg agatcggtca tattttcaaa ctcggaactc
    18721 gctattcagc aagcatggga gcagatgtct tggatgaaaa tggtcgtgct gtgccaatca
    18781 tcatgggatg ttacggtatc ggtgtcagcc gtcttctttc agcagtgatg gagcaacacg
    18841 ctcgcctctt tgttaacaaa acgccaaaag gtgaataccg ttacgcttgg ggaatcaatt
    18901 tccctaaaga attggcacca tttgatgtgc atttgattac tgtcaatgtc aaggatgaag
    18961 aagcgcaagc cttgacagaa aaacttgaag caagcttgat gggagctggt tatgaagtct
    19021 tgacagatga ccgtaacgaa cgtgtcggag tgaagtttag tgatagcgat ttgattgggt
    19081 taccaatccg tatcactgtt gggaagaaag cagctgatgg catcgtagaa gttaagatta
    19141 aggcgactgg tgacaccatt gaggttcatg cagataacgt gcttgaaacg cttgaaatcc
    19201 taagcaagaa ataaaaacta taatcagaag aaaaacaagg aaaaaatgta actagttttt
    19261 accttgtttt ttctgtataa tgggagaaat gagtagataa agaggtaaat gtatgctaag
    19321 atttccaaag gattttgtct ggggctcctc tacttctgga ccgcagacag aaggacgtgt
    19381 agctggtgac ggtaagggag acaatctctg ggattactgg ttccaagtgg agccaaatcg
    19441 ttactataat gggattggtt cagataagac atcgactttt tatgaaaatt gggagcggga
    19501 tattgagctt ttgttagaga ctggtcacac agcctttcgg acttctattc agtggtcacg
    19561 gatttttcca caaggctgtg gaaaagtcaa ccctcaaggt gtggattttt atcgtaaggt
    19621 ctttgaggct attaaggcta aaggaattcg tctgttagtc aatctctatc attttgattt
    19681 accttttgcc cttcaagagg atggtgatgg ttgggaaaat aaggcaacag tcttagccta
    19741 tgaagactat gctcgttttt gttttgagac ttatggagat ttagtggatc aatggattac
    19801 ctttaacgag cccatcgttc ctgtagaatt tggttatttt tatgatgccc attatccaca
    19861 taaggtggat gcagaggcag ctgttaaggt agcctatcat acacaattgg ccagcagtcg
    19921 ggctgttaag gcttgccatg aacttttgcc tgattccaag attgggattg tcctcaactt
    19981 gacaccggct tatccacgta gccagcatcc tgctgatgtc aaggcagctc gtattgcggc
    20041 cctttttcag gcccaatctt tcttagatcc atctgtcttg gggacttatc cacaggagtt
    20101 ggtagaaatc ttgcatgaac acggtctttt acctgatgct acagaggaag agttggaact
    20161 cattcgtgat aatacggtgg acttccttgg tgtgaactac tatcaacctt tgcgtgttat
    20221 ggctcctcga tttgctaagc atccagagag tccactctta ccagaacatt tttacgagcc
    20281 ttatgtgatg cctggacgta aaatcaattc tcatcgtggt tgggagattt atgagcaagg
    20341 gatttatgac atcgcccaaa atatcaagga aaattatggc aatattgagt ggatgttgac
    20401 tgagaatggt atgggtgttg aaggggaaga aaaattccgt caagatggaa tgattcaaga
    20461 tgattaccgt attgactttg taaaaggtca tcttcgtgaa cttcaccgtg ccattgaaga
    20521 tggtgccaac tgtaagggct acttgatttg gacctttatt gactgctggt catggctcaa
    20581 cagctataaa aatcgctatg gtttggtcga attagacttg gaaacgcaag aacgtcgtct
    20641 gaagaaatca ggccactggt tcaaagaatt aagcgataat aatggatttt aaaaaggact
    20701 ctgactgatt atcccaatcg gtcagagttt ttatgcttac aggagcttaa tttgaactat
    20761 accaattttt actcttgaca agtgaaagaa acaagtatat actgtttttg ctgattctat
    20821 aaaagatgaa ttagactata ccaattttaa ggagaaagca cagcttgcct gtgtcgtata
    20881 tactatgtgt ggaattgttg gtgttgttgg aaacacaaat gcaactgata ttttgattca
    20941 agggcttgaa aagcttgaat accgtggcta tgattctgcg ggaatttttg tcctagatgg
    21001 tgctgataac catttggtga aggcggttgg tcgtattgca gaattgtctg ccaagacagc
    21061 tggtgttgag ggaacaactg gtatcggaca tactcgttgg gctactcacg gaaaaccaac
    21121 tgaggacaat gctcacccac accgctctga gacagaacgt tttgtcttgg tgcataatgg
    21181 ggtgattgag aactatcttg aaatcaagga agaatacctt gcaggtcacc acttcaaggg
    21241 gcagacagat actgaaatag ccgttcattt gattggaaaa tttgcggaag aagaagggct
    21301 ctcagttctt gaagccttta aaaaagctct tcatattatc cgtggttcat atgcctttgc
    21361 cttgattgac tctgaaaatc cagatgtcat ctatgtagcg aaaaacaaat ctccactttt
    21421 gattggtctt ggggaaggct acaatatggt ctgctcagat gctatggcta tgattcgtga
    21481 aaccaaccaa tacatggaaa ttcatgacca agagttggta atcgtcaagg ctgatagcgt
    21541 ggaagttcaa gactatgata gtaacagtcg tgaacgtgct agctatactg cggaacttga
    21601 cttgtcagat atcggtaagg gaacttaccc ttactacatg ctcaaggaaa ttgacgagca
    21661 accaacagtg atgcgtaagt tgatccaagc ctacacagat gaggttggtc aagtagtcgt
    21721 agaccaagct atcattcagg ctgttcaaga cgcagaccgc atctacatcc ttgcagctgg
    21781 gacatcttac cacgcaggat ttgcttctaa gaagatgctg gaagaattga cagatacacc
    21841 agttgaactt ggaatttcat ctgagtgggg ttacggtatg ccacttctca gcaagaaacc
    21901 actcttcatc tttatcagcc agtctggtga aacagcagat agccgtcagg ttttggtcaa
    21961 ggctaatgaa atgggaatcc caagcttgac agtgacaaac gtcccaggtt caactctttc
    22021 tcgtgaagcc aaccatacca tgctccttca tgcaggtcct gaaattgccg tggcatcaac
    22081 caaggcctat acagcgcaaa ttgcagccct tgccttcctt gcaaaagcag tcggagaagc
    22141 aaatggcaat gccaaagcgc aagcctttga tttagttcat gagttgtcaa tcgtagctca
    22201 gtctatcgaa tcaactcttt cagagaaaga aaccattgaa gtcaaggttc gtgagctact
    22261 tgaaacaact cgtaacgcct tttacatcgg acgtggtcaa gattactacg tagccatgga
    22321 agcaagtctc aaacttaaag agatttctta catccagtgt gaaggctttg cggcaggaga
    22381 acttaagcac ggaactattg ccttgattga agaaggaaca cctgttttga ctctcttgtc
    22441 agatccagtc cttgccaacc acactcgtgg aaatatccaa gaggtggcag cccgtggtgc
    22501 aaaagtcctc actatcgcag aagaaaatgt tgctaaagag acagacgcta tcgtccttac
    22561 gactgtacac ccttacctct caccaatttc aatggtcgta ccaacacaat tggtcgctta
    22621 ctttgcaacc ctccaccgtg gcctcgatgt ggacaaacca cgtaaccttg ccaagtcagt
    22681 aacggtagaa tagaatctat gaatatacgg gcgtaaagcc ataggtttat cctataaggt
    22741 tttacagcct attttttatg ttacaaatga tgataagggt ttacttttca ataattatag
    22801 cagattgaat ttagaacagt acacaggaat actaaaatat ttctagaaat taatttgaat
    22861 tttccaattg atttgttcgt atcttatttc aaactactat aaaaagagga agctgggcaa
    22921 aaactcaatt tgaagagaaa attcagtaaa tctttccatg ataaaacgca tcatattaag
    22981 gttttgtaca cctgatatga tgcgttttat catttttaag cctttttgcc cagcctcgtc
    23041 aaaagtaaag ttttggcaca aaatctgtga caaaacttta gttttaaagg tttttaactt
    23101 tgtatatact agttttaaga aaaggaggat gatcctaatg gaagaaaaag tatcattgaa
    23161 agtcagagtt caaaaactag ggacatcgct ttcaaatatg gttatgccca atattggagc
    23221 atttattgct tggggagtgt tgactgccct ctttatcgct gatggctatc tgccaaatga
    23281 acagttagct actgttgttg gtcctatgtt aacgtattta ttgccaatcc tgattggtta
    23341 cacaggtgga tatatgatcc atggtcaacg tggtgccgtt gtaggagcta ttgctactgt
    23401 tggtgcaatc acaggttcta gtgttcctat gtttatcgga gctatggtaa tgggctcact
    23461 gggaggatgg actatcaaga aatttgatga aaagttccag gaaaaaattc gtcccggatt
    23521 tgaaatgtta gttaataatt tctcagctgg tctcgttggt tttgcattat tgcttttggc
    23581 tttctacgca atcggtccag tcgtatcgac tcttactgga gctgttggga atggtgttga
    23641 ggctattgtt aatgctcgcc tccttcctat agctaatatt atcatcgaac cggctaaagt
    23701 ccttttcctc aataatgccc tcaatcatgg catttttact cctctgggag tagaacaggt
    23761 agctcaagct ggtaagtcaa ttctcttcct attggaagct aatcctggac caggcctggg
    23821 aattctatta gcttatgctg tattcggtaa aggttctgct aaatcttctt cttggggggc
    23881 aatgcttatt catttcttcg gagggattca tgaaatttac tttccttatg ttatgatgaa
    23941 gcctactcta tttttagctg ctatggcagg aggtatctct ggaactttta cttttcaact
    24001 cttagacgct ggtcttaaat ctccagcttc accaggttct attattgcga ttatggctac
    24061 ggcgccaaaa ggcgtttggc cccatctaaa tgttcttcta ggtgttttag tggcagcagt
    24121 tgtttctttc cttgtagcag cccttattct tcatgcagac aagtcaactg aggattcgct
    24181 cgaagctgct caggcggcta cccaagcagc taaggctcag tctaaaggtc agttagtatc
    24241 aacttctgtt gatgcagttg tttcgacaga ctcagtggaa aaaatcattt tcgcctgcga
    24301 tgctggtatg ggaagctctg ctatgggagc tagtattctt cgagataagg ttaaaaaagc
    24361 aggtctagag attccagtat ctaatcaggc aatctcaaat ttgcttgata caccaaaaac
    24421 attaattgtt actcaggaag aactgacacc aagagctaaa gacaagagtc caagtgctat
    24481 tcatgtttct gttgataatt tcttagcgtc ccctcgttat gatgaaattg tagcttcatt
    24541 aacaggagct tctccaatag cagaaattga aggagatata tcaacttcag catcagtaga
    24601 tagtcaggaa attgacttta accatattga tgctgtagta gttgcttatg gtaaagcaca
    24661 gggatctgca actatgggct gtgaaacgat tcgggctatc tttagaaaca agaatattcg
    24721 tattccagtt tctactgcca aaatttcaga attaggtgaa tttaattcta aaaacataat
    24781 gattgtaaca actatttctt tacaggcaga agtgcagcaa acagcaccga attctcaatt
    24841 tcttattgtg gatagtttag taacaacacc agaatatgac aaaatggctg ttagaatgta
    24901 caaatagaac tagaggtttc taaattacga atgctattaa ccaaacgaga agaacaatta
    24961 ttgaaggctt tcctacatgt agggaagctt tcaatgcaag acatgactga aatcttacag
    25021 gtttcatcta gaacaattta tcgaacttta tcagatttga cagatagcat ggagcaatat
    25081 ggaatcgaaa taacgaagca tgggaaatac tatattttga ctggagagtt ggatgatttg
    25141 ccgacagaac ttgaagtgtt agttgagtat agtccccaag aaagacaaga gttgattacc
    25201 tatcgccttc tgactgagag tggttttgtc accaatgaag cattgcaaga gtgcatgaaa
    25261 gtcagtaatg taactattat tcaggatatt tcagatattg ataagcgtct tttagacttt
    25321 gatctgaaaa ttgaacgaca aaaaggttat cgtatttctg gtgattcagt tggtaagaga
    25381 agatttttgg ctattttact gacaaactgt atctcagtag cagatttttc aaccggtaat
    25441 tttgggagct ttgatatttt agaagcagat agaactaggc tggccagtca gattgttaat
    25501 aagcaactgt caggttttcc agatatggat gctaggatga agatgttttt tgcgatcttg
    25561 ttatctctta taggtcagga gcaaaacatt gaaaattcac ctaatactag taagcaggct
    25621 ttggaaattt ctcaaaaaat ttttcaagct tactctaagc agactgcaca attttatagt
    25681 attcaggaaa ttatctattt tgcgagcatc ttagatgaat taatcattaa acgtcaggac
    25741 aatccgctct ttacggagaa atttgatggt gaatttttct acaatatttc aaatctgatt
    25801 gatacggttt ccatgtatac caagattgac ttttttaagg acaaggtttt attcaatttt
    25861 cttttccatc atattcggct cagtttaggc gtccctatcc tttttcaggg tgaaaatttg
    25921 ccagaatctg tccagatttt agttgaaagg aataaatttc tttatacagt catcagtctt
    25981 ttagtgaatg atatttttcc gaaatatctt catacagagt atgagtatgg catgattgcc
    26041 ctacatttta tctctagctt aggccgtagt ccagagattt atccagtccg tgttttgctt
    26101 ttaacggatg aacgtcgggt cactagagat ttattagtca gtaaaattaa gagtgttgct
    26161 ccttttgtag agttgataga tattcagtct ctagtagatt accacagtat tgatctcagt
    26221 cagtatgatt atattttatc taccaagccg ctgactaatc aggaaatcga tgtaatttct
    26281 agttttccaa ccgtcaaaga actgcttgaa ttacaggaac gacttcagta tgtacaggca
    26341 catcgtacaa ttgtcgcgcg tgatgctatc gctccagaga aaagttatga cttgcaagat
    26401 tatttaatat ctagtagtca gcttttgagt caattcgagt tggttcaatt ggagaataat
    26461 caatcatttg agcacacggt agaacaaatc atccaatatc agaagaatgt gagtgacaga
    26521 gattacctaa caagaaaatt gttatctcac ttccagaata gtcctatggc tattcctaat
    26581 actggtctgg tgcttttaca tagtcagtct agcaaagtaa caacaaatag ttttactatg
    26641 tttgaactca aactacctat ctccgcattg tcaatgaaac gagaggaaga agaggtcaaa
    26701 aggtgtctgc taatgctaat gtctaaagaa gctagcgagg aagcgagaga tttaatgaca
    26761 gctattagtc agtcgattat tgaaaatcat ctttatacag agatttacaa gacgggaaat
    26821 caatccatta tttatcagat gctaaatact atttttaacg aaaaaattaa gaaattggag
    26881 aactaatatg aaacttgaaa aacatttgat taagcttaat aaacaatttt ctaacaagga
    26941 ggaagctatt tgttattgtg ggcaagttct ttatgagggt ggatatgtta atgaagacta
    27001 tattgaagcc atgattgagc gagataaaga gctatctgtt tacatgggta actttatcgc
    27061 cataccgcat ggaacagatg cagcaaaaaa ggatgtcctc aagtctggta ttacagtcgt
    27121 tcaagtccct agaggggttg attttgggaa tgtatctaac cctcaagtgg caacggttct
    27181 ttttggtatt gctggtattg gtaatgaaca cttagaaatt attcagaaaa tttctatctt
    27241 ctgtgcagat gtagataatg ttcttaaact agcagatgct cagtcaaaag aggaagtatt
    27301 gcgcttattt gatgctgttg aataattgaa tttcgtcatt tgtcatctag tatatatgtc
    27361 cctcaaatag gaaaaggaga aattgaatga aacattctgt tcattttggt gccggtaata
    27421 tcggtcgtgg ttttataggt gaaattctat ttaaaagtgg tttccatatt gattttgtgg
    27481 atgtcaataa tcagataatt catgctctaa atgaaaaggg caagtatgaa attgaaattg
    27541 cacagaaagg acagtctcgt atagaagtaa ctaatgtggc tggcattaat agcaaagaac
    27601 atcctgagca agtcattgaa gcgattcaaa agacggatat tattactact gcaatcggac
    27661 ctaatatact cccttttatc gccgaacttc tagccaaagg aatcgaagct cgccgagttg
    27721 caggaaatac acaggcattg gatgttatgg cctgtgaaaa tatgattggc gggtctcaat
    27781 ttctttatca agaagtcaag aaatatttaa gtccggaagg tttgacattt gctgataact
    27841 acataggttt tccaaatgct gcagtagaca ggattgttcc agcacaaagt cacgaagatt
    27901 ccctttttgt tgtggtcgaa ccctttaatg aatgggtcgt ggaaaccaag cgtcttaaaa
    27961 atccagattt acgtctaaaa gatgtgcatt atgaagaaga tttagaaccc tttattgagc
    28021 gaaaactttt ttcagtcaat tctggacatg caacttcagc ttacattggt gcgcattatg
    28081 gtgccaagac aattttggaa gctcttcaaa atcctaatat caaatctcgg attgaatctg
    28141 tattagctga aattcggagt ctcttgatta ccaaatggaa ctttgataaa aaagaattgg
    28201 agaattatca caaagtcatt atagaacggt ttgaaaatcc tttcatagtg gacgaggtta
    28261 gtcgcgtagc tcgtactcca atccgaaaat taggctataa tgaacgattc atccggccga
    28321 tacgtgaatt gaaagaactc agtttgtcat ataaaaacct acttaaaaca gttggctatg
    28381 cctttgacta tcgcgatgta aatgatgaag aaagtattcg attaggtgaa ttgttggcta
    28441 aacaatcagt caaagatgtt gttatacaag ttacaggttt agacgaccca gaattgattg
    28501 agcaaattgt agagtatatt taatcttttt cgaaaatctc ttcaaatcag gttagcatcc
    28561 atctgcaacc tcaaaacagt attttgagct gacttcatca gttctatcta ccacctcaaa
    28621 gcagtgcttt gagctgactc cgtcagtctt atctgcaacc tcaaaacagt gctttgagcg
    28681 cctgcggcta gcttcctagt ttgctctttg attttcattg agtgttagaa taatttttca
    28741 aattgaagga cagagataga caaggagaat cacaatggta gaattgggaa tttcaacatt
    28801 tggggaaata acggagcttg aagggactgg acaaacttac agtcatgctg aacgcattcg
    28861 ccagttggtg gcagagattg agctggctga caaggttggt ttggacgtat atgggattgg
    28921 cgagcaccat cgggcggatt ttgcagtatc agtcccagag attgtcctgg ccgctggggc
    28981 agtcaatatc aagaaaatcc gtttgaccag tgcagtcagc attctgtcaa gcatggctct
    29041 gattcgtttg ttccaacagt atgccactat cgatgctttg tcaaatggac gatcggagat
    29101 tatggctgga aggggctctt tcacggaatc tttccctctg tttggttatg acttgaaaga
    29161 ctacgactct ctttttgatg agaaattaga cttgcttcag ttagtcaatg aaaagaccaa
    29221 gttagactgg caaggtcgat tgactcaaac gattgctggt aaagaagttt atcctcgtcc
    29281 agtttaggac aaattgccct tgtggatagc tacaggtggt catgtcgaat caacagtgaa
    29341 gattgctcag gctggtctac cgattgtata tgctattatt ggtggtaatc cacgttattt
    29401 taaaaagttg attcaggctt atcgtgagat tggaagcgaa gcgggccatg ctgacaaaga
    29461 cttgaaagtg ggagcccatt cttgggggtg gattgcggaa gatggtgagc aggcggtgaa
    29521 agattatttc catccgacta agcaagtggt ggatgctatt tccaaagacc gtccgcactg
    29581 gcaggaattg cgttatgagc aatatttgga gcaggtaggg ccaaatggcg ccatgtttgt
    29641 tggcaatcca gatcaggtgg ccaaaaaatt gattcgcatg atagaggatt taggattgga
    29701 ccgcttcatg cttcatctac cgcttggttc tatgcctcat gaccaggttc tgagagctat
    29761 tgaactcttc ggaacacaag ttgcacccaa agtacgagct tattttgcta tgaaagaggc
    29821 ttaataaaaa atcctaatca agtttattag gacaacaaat attgtacaaa aattaatccc
    29881 ccgagctata atgcttgggg gatttttcta taggagggct agtttagttc tcttttttat
    29941 tttttagtaa gaaaccgaga ccaaggagcg caaggaggct gattcctgca aataggagtt
    30001 tgttttcgtt tttgattcct gtatttggaa gttcagcttg tttatctggg gttgcaggta
    30061 tattttcctt gctagagttt tctaccgatt cgtttcgaac cgcttctttt acagatgatg
    30121 cttgtgcttc ttgtgctggt tgttcagctt gtgaatcagc tgtagcttgg ctaggtttat
    30181 tttccgcatc agctactttg gcatctggtt tagtagaatc aggtctagct tctggagctg
    30241 gatcttgatg ttcaggcttg gaaggggttg agtctggttt ctcttctgca gttgactcat
    30301 ggctagttcc gttttgagag actcgaagaa cagtagctgt aagggcattc aatttcaagc
    30361 ctttttcagt ccattcaagt cctttcgggt tggcaattcc gactggtcct gcttggtttt
    30421 catctgccaa aacttccgca tttcttagat gtgcaaaggc agttcccaaa ttaaattcgc
    30481 gagctttttc atccgcattg acaaagactg cgtagatatc gccgtttgga gcagtgattt
    30541 ggtagccaat cactacatcc tctttttcca caccattttg gcctgggaca gtgatgaggt
    30601 ggacacggtc tttgatatct tgaagactct taagtcggaa ggcatctgta gattgacgaa
    30661 gggcaatcaa acctttcata tagtcacggc tcttgacatt ttcaggataa gctttaccat
    30721 ctgtagcctt agtccagtca aacttgttga ctgcatcgct agaatcgtaa gaatcatgga
    30781 tgaagtaagg atagtcaaat gggttgccgt ccttatcacg caacaagtga gatttgtttg
    30841 gaaccttatc ctctgctact ggagtcttgt aggctgggtc acggaattgt ttagtacgtc
    30901 catattcctg accggagtgg ataaatggag ttccttgagc tgtcaagacc atgagatttc
    30961 caagtcgtaa acgacggtgg acttcagcat agttctcagc cttgcttggg tcttttttga
    31021 tagactgggc aatgatgtca aagagggtca agttatcatg ggctgcgatg tattggatga
    31081 catctccagg gctgtcagct tcaaagttag ttggttgagc aatgagattt ttaaagatgg
    31141 tgttgacatc acgcttgcca cctgtgataa aggcaggttg accttcgttt ggataaccag
    31201 atttgaggtt gttacggatg tcatctgaaa agacagcgac agtatcggta tgtttcatcc
    31261 aatcttggtc agcagcttta gtaggcatgt tttcatcacc ggcataggtt ctccaacctt
    31321 caccaagcat gatgaggttt ggattgaggg cgcgtgcagc cttgtaagct tcttcgatag
    31381 aagtggcgtc atggtctccc atcatatcga agcggaagcc atccactttg taggtatcca
    31441 ctaggtattt gatagagtca actaggagcc gtttggtcat atggtgggtt gtccccaagc
    31501 gtccaccacc aaagctagtt cgaggtgtgc catcggcatc cataaagtgg tagtagtttg
    31561 gctctaggtc ttcaaagata tcgactttgg ctgtgtggtt ataaacgaca tctaggatag
    31621 ctcccatacc acgtttgtgg atttcgttga tgaggttttt aaattctgcg attcgttttt
    31681 ctggattctt aggatcgctt gagtacatac cagtcaatga gaagtagttt tgagggtcat
    31741 atccccagtt gtagttgctg ttgcttgaag catagtcaga caagcgttca tggtttttca
    31801 attcattgac aaagtagtaa gacaagactg gaaggagctg gatgtgggtt acacccaagt
    31861 ctttgaggta gtctagtttt tcgataaagg cttcaaaagt cccaaatggt ttggtcaagt
    31921 cttttgcaat ggcaggatct gaagtgaaat cacgcacatg agcttcgtag ataacggcgt
    31981 cttcacgagt cttgaaattg tgaatcttac cataagtcaa gtcttgaggt ccgagtttag
    32041 ctggatctac aaaggcggct ttagccactt tatgggcatc gtcaatcttg gcatcgtcgc
    32101 tattccaagc agcaagagat ttagcgtaag gatcgagtgc aagaacagtt ttaccttgac
    32161 gctcgatttg gtattgataa tagtagccag tgaaatctgt gattccgagt ttgtttgtgc
    32221 tgtctagagt ttgtttccaa gttcctcttt cccctttttc gagagcgaca gttccaacta
    32281 ctttgtcagg gtcattcttg tcgtagacaa caacagaaac cttatcagca cttggtgacc
    32341 aaagggtcaa atcaacttgt tttccttctt cttttaggtc agctcccagt ttgccatcat
    32401 agctgtatgt ctcatctttc aggcgccagc ttgttttggt agtgaattgg tcggaattgt
    32461 agctaacagt ataaggatgt tttgtgtcag agaaatctcc gctgtaggtc actttcttac
    32521 cagcttcatc gattgcaaca tcggtaatag ttaccttgtt tcctaggtga ttagtgatgt
    32581 tggagtgttt gaggatatct tcttttttag caccgacaag tgttgaaaag ctactttcaa
    32641 tgctagaagt gcctacgtgt tgggctcctg tcatacggat atcatggaca tagtatggat
    32701 ttgtgtaaat cgattcatca tcgtctttta ggaaaatttg gctatgattt ttcaaatctg
    32761 tgaacttata attttcttta cggattttca cgtcgtctcc ttgtttgctc tcatctagta
    32821 ataaaaatcc aaattctctt gcggcttcat taagaggaat gtcgatatag cggccatatt
    32881 tgcctgtagc cgtaaagtct gttccgtcag gccattgagc gctacttgga tttttcacat
    32941 ctccccagta ccagagagat ttcttgtcat agttgccatc tgtgcggtag tagttgacgc
    33001 gaacagttcc tgcaggctgt ggctcgtaag agaaaacctt gtaatcttgg tctaaccaag
    33061 cctcgttcat ttttggaact agtttttcta cagatttatc gccggttaga ttttttccag
    33121 ctgtattgtt gatgaggaag ctaattttct tggcttgttc tccctttaat ttgacatcta
    33181 ggtaatagcc gtagtcatct ttcttggcat ccttgaagga caaagctccg tttggccagt
    33241 tttcagatgg tttttcaaca tcgtcccaag tccatagtcc ttgagcatcc ttgttttctt
    33301 caggaagttt tttgacatgg atacggaagt agttatcttc gatgggctct tctgccttag
    33361 tttcagttgt tactggacta gtagaagtag ttggctctgt tgcaggtttt tcttctgttt
    33421 tctctaggga agcgtttgca tttctaggtg aagaaatatc actttcgttc ttaccagagc
    33481 cagctgctgt atcagtaaga ggttgggcaa gggtggttgt atttctgttg ttgggttcgt
    33541 tagtggttgg tgtactttcg tcggatgaga tagttggtgt agccatggca agcaagacaa
    33601 ggcttgcgcc gataaggaca gaaccagttc catttttgag ggaacggatg ctgtagacca
    33661 tttttttctc agtgtgagat ggtgtttttc tcataatgat tctccaatca ataaatttct
    33721 atatcagtat agcatgtagt aaaacaatat gcaagcgttt tctttgattt gtgaaaaaaa
    33781 ttcttacttt tgagaagttt tctgtactat tttaacccca attattcacc ccaaatctaa
    33841 aaaccatcca gaatccttgc cttagcttag atcctggatg gtttcttttt tcacccaatg
    33901 ggtgtttttt actagacaaa aaagagtttc ccctttatgg tataagtgta gaaaaaaaca
    33961 caaaaagaaa ggaaactcac atgaacagtt taccaaatca tcacttccaa aacaagtctt
    34021 tttatcaact atctttcgat ggaggtcatt taacccagta tggtggtctt atcttttttc
    34081 aggaactttt ttcccagttg aaactaaaag agcggatttc taagtattta gtaacgaatg
    34141 accaacgccg ctactgtcgt tattcggatt cagatatcct tgtccagttc ctctttcaac
    34201 tgttaacagg ctatggaacg gactatgctt gtaaagaatt gtcagctgat gcctactttc
    34261 caaaattgtt ggaaggaggg cagcttgctt cacagccaac cttatcccgt tttctttcca
    34321 gaactgacga ggaaacagtc catagtttgc gatgcctcaa ccttgaattg gtcgaattct
    34381 ttttacagtt tcaccagcta aaccaactca ttgtagatat cgattctacc catttcacaa
    34441 cttatggcaa gcaagaaggt gttgcttata acgcccacta tcgtgctcat ggctatcatc
    34501 ctctttatgc tttcgagggg aagacaggtt attgtttcaa tgcccagctt cgtcctggta
    34561 atcgttattg ttctgaagag gcagacagct ttatcacacc tgttttagaa cggtttaatc
    34621 aacttctctt tcgaatggat agtggctttg cgaccccaaa attatacgat ttaattgaaa
    34681 aaacagggca atactacctc ataaaactca agaaaaatac tgttctgagc cgtcttggag
    34741 acctttccct cccttgccca caggatgagg acttaaccat cttgccccac tccgcctact
    34801 cagaaactct ctatcaagca ggatcttggt cgcacaagcg tcgtgtctgc cagttctctg
    34861 aacgaaaaga aggaaacttg ttctacgatg ttatttctct cgttgcaaat atgacgagtg
    34921 gaacaagcca agaccagttt cagctttatc gtggacgtgg tcaagccgag aatttcatca
    34981 aggagatgaa ggagggattt tttggcgata aaacggatag ttcaacctta atcaaaaacg
    35041 aagttcgtat gatgatgagc tgtatcgcct acaatctcta tctttttctc aaacatctag
    35101 ctggaggcga cttccaaact ttaacaatca aacgcttccg ccatcttttt cttcacgtgg
    35161 taggaaaatg tgttcgaaca ggacgcaagc agctcctcaa attgtctagt ctctatgcct
    35221 attccgaatt gttttcagca ctttattcta ggattagaaa agtcaacctg aatcttcctg
    35281 ttccttatga accacctgga agaaaagcgt cgttaatgat gcattaaaga acagtcgaga
    35341 tgaaaaaatc gtgtgacgca ccaagggagg agtctgccct tttgaggaaa tctagcgagg
    35401 aaaaacgata ctggaacagc agaaagtaaa actgacctca tgaggaggaa gaaagtggct
    35461 catgaggtca ggggttttgt aagttacatc tagttgagag aggtatgaat gatttgggtt
    35521 tatatatcag tataaatgac ggagataaaa atgtcacata agccaagccg tattattagg
    35581 aagatgatgt gttcccagct atttttattc agaaattgat ctctaacatt accaataaaa
    35641 aagaaaaata tcttgacaag caagggaaaa ttttgttaca ataatagacg gtacttttta
    35701 cttttggtct ctcaagagtg tacagggacg tgctgacaaa tgttgcaaaa gtacacacag
    35761 atgatatctg tcaccaagtg tatcatcacc aaaaataaaa aaacacagga gaatgtagat
    35821 gcctacaatt aaccaattgg ttcgcaaacc gcgtaaatca aaagtagaaa aatctaaatc
    35881 accagctttg aacgttggtt acaatagtca taaaaaagtt caaacaaacg tttcttcacc
    35941 acaaaaacgt ggtgttgcaa ctcgtgttgg aacaatgaca cctaaaaaac ctaactcagc
    36001 ccttcgtaaa ttcgctcgtg tacgtttgag caaccttatc gaagttactg cctacatccc
    36061 aggtatcgga cacaacttgc aagagcacag cgtggtgctt cttcgcggtg gacgtgtaaa
    36121 agaccttcca ggggtacgtt accatatcgt ccgtggtgca cttgatactg caggtgttaa
    36181 cgatcgtaaa caaggccgtt ctaaatacgg tactaaacgt ccaaaagcat aaggaaaggg
    36241 gataaagaga aatgagtcgt aaaaatagag ctccaaaacg tgacgtattg ccagatccgc
    36301 tatacaattc acaactagtt actcgtctta tcaaccgcgt tatgcttgat ggtaaacgtg
    36361 gtactgctgc ttcaatcgtt tacggtgctt ttgagcaaat caaagaagct actggcaacg
    36421 atgcacttga agtatttgaa acagctatgg aaaacatcat gcctgtactt gaagtacgtg
    36481 cacgtcgtgt tggtggttct aactaccaag tcccagttga agttcgtcca gaacgtcgta
    36541 caacacttgg acttcgttgg ttggtaacaa tcgctcgtct tcgtggtgaa cacacaatgc
    36601 aagaccgtct tgcaaaagaa atcttggatg ctgctaacaa cactggtgca gctgttaaga
    36661 aacgtgaaga tactcaccgt atggctgaag ctaaccgtgc attcgcacac ttccgttggt
    36721 aagataggat gcgaaagcgt taagaaagtc ccagagaaaa tagggaatcg aagcaggttg
    36781 cggttgcaac caatgagatt catctttttc tccagacttt tagcttgagc tcaactaaat
    36841 catgatgcta ggcacggtaa ggatgcaagg tgaaaatagg aaactgacgc agtattcaac
    36901 gaatacaagg agttttatct ttttcacgca gcatcccgtt ccagctcaca tcggctaact
    36961 aactttagcc cgggttcaaa ttagctaaat cgattagtat tagctataac tcagcttacc
    37021 atctagtaag ttgaaaccaa caatagcatg aaaacattga gaacgggtag gtcctgccta
    37081 tccgttttta ttaaaatcgt gttataatag aatagaaatc aaaaataaat aggagaaaca
    37141 aacctcatgg cacgcgaatt ttcacttgaa aaaactcgta atatcggtat catggctcac
    37201 gtcgatgccg gtaaaacaac aactactgag cgtattcttt actacactgg taaaatccac
    37261 aaaatcggtg aaactcacga aggtgcgtca caaatggact ggatggagca agagcaagaa
    37321 cgtggtatca cgatcacatc tgctgcgaca acagctcaat ggaacaacca ccgcgtaaac
    37381 atcatcgaca caccaggaca cgtggacttc acaatcgaag tacaacgttc tcttcgtgta
    37441 ttggatggtg cggttaccgt tcttgactca caatcaggtg ttgaacctca aactgaaaca
    37501 gtttggcgtc aagcaactga gtacggagtt ccacgtatcg tatttgccaa caaaatggac
    37561 aaaatcggtg ctgacttcct ttactctgta agcacacttc acgatcgtct tcaagcaaat
    37621 gcacacccaa tccaattgcc aatcggttct gaagatgact tccgtggtat cattgacttg
    37681 atcaagatga aagctgaaat ctatactaac gaccttggta cggatatcct tgaagaagac
    37741 atcccagctg aataccttga ccaagctcaa gaataccgtg aaaaattgat tgaagcagtt
    37801 gctgaaactg acgaagaatt gatgatgaaa tacctcgaag gtgaagaaat cactaacgaa
    37861 gaattgaaag ctggtatccg taaagcgact atcaacgttg aattctttcc agtattgtgt
    37921 ggttcagcct tcaaaaacaa aggtgttcaa ttgatgcttg atgcggttat cgactacctt
    37981 ccaagcccac ttgacatccc agcaatcaaa ggtattaacc cagatacaga cgctgaagaa
    38041 actcgtccag catctgacga agagccattt gcagctcttg ccttcaagat catgactgac
    38101 ccattcgtag gtcgtttgac attcttccgt gtttactcag gtgttcttca atcaggttca
    38161 tacgtattga atacttctaa aggtaaacgt gaacgtatcg gacgtatcct tcaaatgcac
    38221 gctaacagcc gtcaagaaat cgacactgtt tactcaggtg atatcgctgc tgccgttggt
    38281 ttgaaagata ctacaactgg tgactcattg acagatgaaa aatctaaaat catccttgag
    38341 tcaatcaacg ttccagaacc agttatccaa ttgatggttg agccaaaatc taaagctgac
    38401 caagacaaga tgggtatcgc ccttcaaaaa ttggctgaag aagatccaac attccgcgtt
    38461 gaaacaaacg ttgaaactgg tgaaacagtt atctcaggta tgggtgaact tcaccttgac
    38521 gtccttgttg atcgtatgcg tcgtgagttc aaagttgaag cgaacgtagg tgcgcctcaa
    38581 gtatcttacc gtgaaacatt ccgcgcttct actcaagcac gtggattctt caaacgtcag
    38641 tctggtggta aaggtcaatt cggtgatgtg tggattgaat ttactccaaa cgaagaaggt
    38701 aaaggattcg aattcgaaaa cgcaatcgtc ggtggtgtgg ttcctcgtga atttatccca
    38761 gcggttgaaa aaggtttggt agaatctatg gctaacggtg ttcttgcagg ttacccaatg
    38821 gttgacgtta aagctaagct ttatgatggt tcatatcacg atgtcgactc atctgaaact
    38881 gccttcaaga ttgcggcttc actttccctt aaagaagctg ctaaatcagc acaaccagct
    38941 atccttgaac caatgatgct tgtaacaatc actgttccag aagaaaacct tggtgatgtt
    39001 atgggtcacg taactgctcg tcgtggacgt gtagatggta tggaagcaca cggtaacagc
    39061 caaatcgttc gtgcttacgt tccacttgct gaaatgttcg gttacgcaac agttcttcgt
    39121 tctgcatctc aaggacgtgg tacattcatg atggtatttg accactacga agatgtacct
    39181 aagtcagtac aagaagaaat tattaagaaa aataaaggtg aagactaatc cgtcctcact
    39241 ctagaaggaa gtcacttagt ggcttccttt tgtctttaga aaatacctct aaatatggta
    39301 aaatagtaga agaataatgt gaggaaaatg aatgtcaaat agttttgaaa ttttgatgaa
    39361 tcaattgggg atgcctgctg aaatgagaca ggctcctgct ttagcacagg ccaatattga
    39421 gcgagttgtg gttcataaaa ttagtaaggt atgggagttt catttcgtat tttctaatat
    39481 tttaccgatt gaaatctttt tagaattaaa gaaaggtttg agcgaagaat tttctaagac
    39541 aggcaataaa gctgtttttg aaattaaggc tcggtctcaa gaattttcaa atcagctctt
    39601 gcagtcctac tatagggagg ctttctctga aggtccatgt gctagtcaag gttttaagtc
    39661 cctttatcaa aatttgcaag ttcgtgctga gggtaatcag ctatttattg aaggatctga
    39721 ggcgattgat aaggaacatt ttaagaagaa tcatcttcct aatttagcca aacaacttga
    39781 aaagtttggt tttccaactt ttaactgtca agtcgagaag aatgatgtcc tgacccaaga
    39841 gcaggaagag gcctttcatg ctgaaaatga gcagattgtt caagctgcca atgaggaagc
    39901 gctccgtgct atggaacaac tggagcagat ggcacctcct ccagcggaag agaaaccagt
    39961 ctttgatttt caagcgaaaa aagctgcagc taaacccaag ctggataagg cggagattac
    40021 tcctatgatc gaagtgacga cagaggaaaa tcgtctggta tttgaagggg ttgtttttga
    40081 tgtggagcaa aaagtgacta gaacaggtcg tgttttaatc aactttaaaa tgacggacta
    40141 tacttcaagt ttttctatgc aaaagtgggt taaaaacgag gaagaggccc agaagtttga
    40201 cctcatcaag aagaattctt ggctccgagt tcgagggaat gtggagatga ataacttcac
    40261 acgcgatttg actatgaacg tacaggatct gcaggaagtt gttcactatg agcggaagga
    40321 tttgatgcca gaaggtgagc gtcgggttga gtttcatgct catactaaca tgtcgactat
    40381 ggatgctttg ccagaggtcg aagagattgt tgcaacagct gctaagtggg gacacaaggc
    40441 ggttgctatc acggaccatg ggaatgtcca gtcctttcca catggctata aggcggctaa
    40501 gaaagcggga atccagctga tctatggaat ggaagccaat atcgtggagg accgtgtccc
    40561 tatcgtctat aacgaagtgg agatggactt gtcagaagca acctacgtgg tctttgacgt
    40621 ggaaacgacg ggactttcag ctatctataa tgacttgatt caggttgcgg cctctaagat
    40681 gtacaagggg aatgttattg ctgaatttga tgaatttatc aatcctgggc atcccttgtc
    40741 agcttttact acagagttaa ctggaattac agatgatcat gtcaaaaatg ccaaaccact
    40801 agaacaagtt ttgcaagaat tccaagaatt ttgcaaggat acggtcctag ttgcccacaa
    40861 tgctaccttt gacgttggct ttatgaatgc taattatgag cgtcatgatc ttccaaagat
    40921 tagtcagcca gttattgata cgctggagtt tgctagaaac ctctatcctg agtataaacg
    40981 ccatggtttg gggcctttga ccaagcgttt tggtgtggcc ttggaacatc accacatggc
    41041 caactacgat gcggaagcga ctggtcgtct gcttttcatc tttatcaaag aggtagcaga
    41101 aaaacatggt gtgaccgatt tagctagact caacattgat ctaatcagtc cagattctta
    41161 caaaaaagct cggatcaagc atgcgaccat ctatgtcaag aatcaggtag gtctaaaaaa
    41221 tatctttaag ctggtttcct tgtctaatac caagtatttt gaaggagtgc cacggattcc
    41281 gagaacggtt ctagatgccc atcgagaggg cttgatttta ggttcagcct gttcagaggg
    41341 tgaagttttt gacgtggtcg tttctcaagg tgtggatggg gcggttgagg tggccaagta
    41401 ttatgacttt atcgaggtca tgccaccggc tatctatgcg cccttgattg ccaaagagca
    41461 ggtcaaggat atggaggaac tccagaccat tatcaagagt ttgatagagg ttggagatcg
    41521 ccttggcaag cctgttctgg ctacgggaaa tgttcactat atcgaaccgg aagaagagat
    41581 ttatcgtgaa attattgtcc gtagtttggg acagggtgcg atgattaatc gaactatcgg
    41641 tcatggtgaa catgcccaac cagcaccact tccaaaggct cattttcgaa cgactaatga
    41701 gatgttggat gaatttgcct ttttgggaga ggaactggct cgtaaactgg ttattgaaaa
    41761 cactaatgcc ttggcagaaa tatttgaacc cgttgaagtc gttaagggtg acttgtatac
    41821 gcctttcatc gacaaggctg aagaaacagt tgctgagttg acctataaga aagcttttga
    41881 gatttatgga aatccgctgc cagatattgt tgatttgcgg attgaaaaag aattaacatc
    41941 catactgggg aatggatttg ctgtgattta tctggcatcg cagatgctgg tgcaacgttc
    42001 taatgaacgg ggttatttgg ttggttctcg tgggtctgtc ggatctagtt tcgttgcgac
    42061 catgattggg attacggagg tcaatcctct ctctcctcac tatgtctgtg gtcagtgtca
    42121 gtacagtgag tttatcacag atggttcgta cggttcagga tttgatatgc cccataagga
    42181 ctgtccaaac tgtggtcaca aactcagtaa aaacggacag gatattccgt ttgagacctt
    42241 ccttggcttt gatggggata aggttcctga tattgacttg aacttctcgg gagaagatca
    42301 gcctagcgcc cacttggatg tgcgtgatat ctttggtgaa gaatatgcct tccgtgcggg
    42361 aacggttggt acggtagctg ccaagactgc ctatggattt gtcaagggtt acgagcgaga
    42421 ttatggcaag ttttatcgtg atgcagaagt agaacgcctc gctcaaggag cggcgggtgt
    42481 caagcggaca acaggccaac acccgggggg aatcgttgtt attccgaact acatggatgt
    42541 ctacgatttt acgcctgtcc agtatccagc agatgatgtc acggctgaat ggcagaccac
    42601 tcactttaac ttccacgata tcgatgagaa cgtcctcaaa ctcgatgtac tgggacatga
    42661 tgatccgacc atgattcgaa aacttcagga tttgtctggt attgacccta atgaaattcc
    42721 tatggatgac gaaggcgtga tggcactctt ttctgggact gatgtgctag gggtaacacc
    42781 tgaacaaatt ggaacgccta cgggtatgtt ggggattcca gagtttggaa caaatttcgt
    42841 acgtggaatg gtagacgaaa cccatccgac aacctttgcg gaattgcttc agctgtctgg
    42901 tctgtcccac ggtactgacg tttggttggg gaatgctcag gatctgatta agcaaggaat
    42961 agcggaccta tcgactgtta tcggttgtcg ggacgacatc atggtttacc tcatgcatgc
    43021 gggtctggaa cctaagatgg cctttaccat tatggaacgg gtacgtaagg gtttgtggct
    43081 aaagatttca gaagaggaga gaaatgacta tatcgaagcc atgaaggcca ataaggtgcc
    43141 agagtggtat atcgaatcct gtgggaaaat taagtacatg ttccctaagg cccatgcggc
    43201 agcctacgtt atgatggcct tgcgtgtagc ttacttcaag gttcaccatc ctatttatta
    43261 ctactgtgct tacttctcca ttcgtgctaa ggcttttgat atcaagacca tgggtgcggg
    43321 cttggaggtc atcaagcgca gaatggaaga aatctctgaa aaacggaaga acaatgaagc
    43381 ctctaatgtg gaaatcgatc tctatacaac tcttgagatt gtcaatgaga tgtgggaacg
    43441 aggtttcaag tttggtaaat tagatctcta ccgtagtcag gcgacagagt tcctcatcga
    43501 cggggatacc cttatcccac catttgtagc aatggatggt ctgggagaga acgttgccaa
    43561 gcaactggtg cgggcgcgtg aagagggaga attcctctct aaaacagaac tacgcaagcg
    43621 tggtggactc tcatcaacct tggttgaaaa gatggatgag atgggtattc ttggaaatat
    43681 gccagaggat aaccagttga gtttgtttga tgagttgttt taaaaaattg cttaataatc
    43741 tattaaaaga ggctaacgta tatccaatag atttacatta gctttctttt ttgttaaaat
    43801 agtctatgga aagagggtga gagtatgtca aagatgagta taagcatccg tctggatagt
    43861 gaggttaagg agcaggccca acaggtgttt agtaatctgg gaatggatat gacaacagct
    43921 attaatattt tccttcgtca ggcaattcaa tatcagggat taccttttga tgttagacta
    43981 gacgaaaatc ggaagttgct ccaagcgtta acggatttag accaaaatcg taatatgagc
    44041 cagtcttttg aatcagtctc agatttgatg gaggacttac gtgcttaaga ttcgttatca
    44101 taaacagttt aaaaaagatt ttaagttggc tatgaagcgt ggtttgaagg cagaattatt
    44161 agaagaagtt ttgaattttc tggttcaaga aaaagaacat cctgccagat atcgtgatca
    44221 ttcattgacg gcatccaagc attttcaagg agttcgtgaa tgccataccc agccagattg
    44281 gcttttggtt tataaagtag acaagtcgga attgatttta aatttgctga ggacaggcag
    44341 tcacagtgat ttattttaat ctattttaag ggggttctca tgaaactaag aatatttgcg
    44401 gaagataagc cggctaagaa ggtatttgaa tatcaattag aacttgctga tcgtacaatt
    44461 cttctatcga cagcactctt gtcaggtgct attgctttag caggaatctt ttctgctttg
    44521 aaagaaaaat aaaaatagaa aagagaaaac agaatggttt taccaaattt taaagaaaat
    44581 ctagaaaaat atgcgaaatt gttggttgcg aacggaatta acgtgcaacc tggtcacact
    44641 ttggctctct ctattgatgt ggagcaacgt gaattggcac atctaatcgt gaaagaagct
    44701 tatgccttgg gtgcgcatga ggtcatcgtt cagtggacag atgatgtgat taaccgtgag
    44761 aaattcctcc atgccccgat ggagcgtttg gacaatgtgc cagaatacaa gattgctgag
    44821 atgaactatc ttttggagaa caaggctagc cgtcttgggg ttcgttcatc tgatccaggt
    44881 gccttgaacg gagtggacgc tgacaagctt tcagcttctg ctaaagctat gggacttgcc
    44941 atgaagccaa tgcgaatcgc aactcaatct aacaaggtta gctggactgt agcagccgct
    45001 gctggacttg agtgggctaa gaaagtcttc ccaaatgctg cgagcgacga agaagcagtt
    45061 gatttccttt gggatcaaat cttcaaaact tgtcgtgtct acgaagcaga tcctgttaag
    45121 gcttgggagg aacatgcagc cattctcaag agcaaggccg atatgcttaa taaggagcaa
    45181 ttttcagccc ttcactacac agcgccagga acagatttaa cacttggttt gccaaagaac
    45241 cacgtttggg aatcagctgg tgctgtcaat gcacagggcg aagaattctt gccaaatatg
    45301 ccgacagaag aggtcttcac agcgcctgac ttccgtcgtg cagatggtta tgtcacttct
    45361 acaaaaccgc ttagctacaa cggaaatatc attgaaggca ttaaggtgac ctttaaggat
    45421 ggacaaatcg tagatatcac tgctgagaag ggtgatcagg ttatgaaaga ccttgtcttt
    45481 gaaaatgcgg gtgcgcgtgc cttgggtgaa tgtgccttgg taccagatcc aagtccaatt
    45541 tctcagtcag gcattacctt ctttaacacc cttttcgatg aaaatgcgtc aaaccacttg
    45601 gctatcggtg cagcctatgc gactagcgtt gttgatggag cggagatgag cgaagaggag
    45661 cttgaagctg cagggcttaa ccgttcagat gttcacgtag actttatgat tggttctaac
    45721 caaatggata tcgatggtat tcgtgaggat ggaacgcggg tacctctttt ccgtaatggg
    45781 aattgggcaa attaaggaga taatatgtta ggaagtatgt tcgttggtct cctagtggga
    45841 tttttagcag gtgctatgac caatcgtgga gagcgaatgg gatgttttgg aaaaatgttt
    45901 ctcggttgga tcggagcctt tctaggtcac ttgctctttg gaacttgggg gccagtttta
    45961 tcaggaacag ctattatccc agcgatttta ggagccatga ttgttttagc tattttttgg
    46021 agacgaggaa gttaatttcc taaatctgat actcaatgaa aatcaaagag caaactagga
    46081 aactagccgc aggttgctca aagcactgct ttgaggttgc agatagaact gacgaagtca
    46141 gctaaaaaca ctgttttgag gttgcagata gaactgacga agtcagtaac atatatacgg
    46201 caaggcgacg ttgacgcggt ttgaagagat ttttgaagag tatgaaacga aaaggaggtt
    46261 ggtcattgta ccagcctcct tttgatatga tataatagtt ctatgagatt agataaattt
    46321 ttagttgcct gtgcggtggg aagtcggact gaggtcaaaa acttgctcaa ggctgggcgc
    46381 gtgactgtaa atggtaaaaa agaaaaatca gctaaattgc agattgatga aaaaatagat
    46441 gagattcgct ttgatgggca agtgttggag tatgaagagt ttgtctacta catgatgaac
    46501 aagcccaaag gagttatctc agcgactgag gatcccaagc acagaaccgt tctggacttg
    46561 ttggatgact tggcgcggag taaggaagtt ttcccagtag gacgcttgga tattgacacg
    46621 catggtcttt tgctcttgac caatgatggt cagctggctc atgttcttct ttcgcccaag
    46681 cgtcatgtgg ataagactta tctggcacaa gtcaagggaa tcatgaccca agaagatgtg
    46741 gagacatttg ctgagggtat tcctctcaaa gactttacct gtcaacccgc tatactggag
    46801 cttgtatcca tagatacaga aaagaatcag agccaaatcc gtgtgaccat tgcagaaggg
    46861 aagtttcatc agatcaagcg tatggtgggc tactgtggca aggaagtggt ggacttgcaa
    46921 cgattgacta tgggaacttt agtattagat gagaacctgg aacgagggga atggcgtcgc
    46981 ttgaccaagg aagaattaga aattctccgc gctaatatta tttaatttag tttaatactc
    47041 aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgtacttgag tacggcaagg
    47101 cgacgttgac gtggtttgaa gagattttcg aagagtataa attcgaaaaa ggtgagggag
    47161 aatgtcctta ccttttatgt tttttagttg cttcctttgt gaaaagagtt ataatagact
    47221 gtagaataaa aggaggaatc tatgaacgcg attcaagaat catttactga taaactattt
    47281 gccaactatg aagcaaatgt aaaataccaa gcgattgaaa atgctgccag ccacaacgga
    47341 atttttgcag ctctggaacg tcgccaaagc catgtagaca acacacctgt tttctcattg
    47401 gatttaacca aggacaaggt cactaaccag aaagcgtctg gtcgttgctg gatgtttgcg
    47461 gctctcaaca ccttccgcca caaactcatc tcgcaataca aattggagaa ctttgagttg
    47521 tcacaagccc acactttctt ctgggataag tatgagaaat caaactggtt cttggagcaa
    47581 gtcattgcga cttcagacca agaattgact agccgcaagg ttagcttctt actccaaaca
    47641 cctcaacaag atggtggtca atgggatatg gtcgtttccc tctttgaaaa atacggtgtc
    47701 gtgcctaagt cagtttatcc tgagtctgtt tcatctagca gcagtcgtga gctaaatgcg
    47761 atccttaata aattgcttcg tcaagatgct caaatcttgc gtgatttgct tgtttctggt
    47821 gcagatcaag tgactgttca agctaagaaa gaagacctct tgcaagaaat ctttaacttt
    47881 cttgctatgt cattaggact tccaccacgc aagtttgact ttgcttatcg cgataaagat
    47941 aacaactaca aaagtgaaaa aggaatcaca ccacaagagt tctacaagaa atatgtcaat
    48001 cttcctttag aagactacgt ttctgttatc aatgctccaa ctgctgataa accttacgga
    48061 aaatcttaca cagttgagat gttggggaat gtggttggta gccgtgcagt tcgttacatc
    48121 aacgttccaa tggagcgctt gaaagaattg gcgattgccc aaatgcaagc aggtgagact
    48181 gtttggtttg gttctgatgt cggccagctc agtaaccgta aggctggaat ccttgcgaca
    48241 gatgtttatg actttgaatc aagcatggac attaaactta ctcaagacaa ggctggacgt
    48301 ttggactata gcgaaagctt gatgacccac gccatggtct tgacaggtgt tgacttggac
    48361 gaaaatggta aatcaaccaa gtggaaggtt gaaaactcat ggggagacaa ggtcggtaca
    48421 gatggttact ttgttgcctc agacgcttgg atggacgaat acacatacca aatcgttgtt
    48481 cgtaaggaat tgctgacagc agaagaacaa gctgcctatg gagcagaacc aattgtactt
    48541 gcaccatggg atccaatggg agccttggct aaataaaagc atagaaaaaa ggaatcagat
    48601 tttagaacct ggttcctttt tagttgcttg attacatgat gtgaagaaca tgtgccacaa
    48661 tacccactgc gaagagggca aggataatag tgattggaga tacttttttc ttaagtaagt
    48721 acatgcaaag taaagtaagg agtagtcctg ataatccagg aatcaacata tccaagtttt
    48781 gttggaaagt agtaactttt tcaggagttt gagacaatcc ttgtcctact tgtgcgaatg
    48841 cttcttggat acctttagac ccttctggca atttatccca atggatataa gccttttcat
    48901 ctagttgaac tttagaaaca tcgaaagcaa atttaatatt tacccagcgt tgaacaagga
    48961 cagcaagaat gaacatccca aggatagaag ctcctttagt gatatcttga aggataccac
    49021 cagacatatc tttagtgatt tctgatccag ccttgtatcc aatctcttga acataccaca
    49081 agaatgacat acgaatcaag ttccatgcaa caaagaagag gagtggcccc aagatattgc
    49141 cagtaagggc aagtgaagca ccgagagatc caaggattgg gcgtactgta aaccagaata
    49201 ctgggtcacc gataccagca agaggtccca tcataccgat tttaacccct tggatagcag
    49261 cgtcatcgat ttccacaccg ttagcacgtt cttcttcaag cgcaagagta acccccatga
    49321 ctggagcagc tacgtatgga tgagtgttga agaactcaag gtgacgctca agagcagcga
    49381 tttgatcttc ttttttagta tagagttttt tgatagctgg aatgagtgta taagcccagc
    49441 ccaagttttg catccgttca aagttccaag acccttgtaa gaaggttgaa cgccaccaaa
    49501 cttttttacg atctgattta gttaattgaa gtttttcagt catgatgttt tcagtccttt
    49561 cttatcttag tagtcttcta ggatatcgcc gattgggtcg ttagaagttg cggctcctcc
    49621 gccaccattt ccaccagttt tagaaaggtg aaggtagata agagcgatag caacaccgat
    49681 agcaccgaat ccgattagag taatatctga cacagcagcg agaacgaaac caagagcgaa
    49741 gaatggccat acttcacgag ttgccatcat gttgataacc atggcgtaac caacggcaac
    49801 gaccatacca ccaccgatag ccataccatc tttgagccag tctggcatgg cactaaggat
    49861 actttgtaca gtttcagttg gtaccataag gagaagagct gcaggaagcg cgatacgaag
    49921 tccttggaaa agtagcgcaa tgaaatgcgc acgctccaca gcgccgaagt cacctttttt
    49981 agcggcagca tctgcggtat gaaccaaacc aactgaaatt gtacgaacaa tcattgtcaa
    50041 gaaaagtcca gctacggcaa gagggatagc aaccgcttgg gcaacaccga taccagtctt
    50101 ggtaaagtca ccaccaagaa ccatgataat ggcagcagcg acagaagcaa gtgcagcatc
    50161 aggagcgata gcagcaccga tatttgacca accaagggca atcatttgaa gcgatccacc
    50221 gaggataatc cctgcttcca agtgacctgt tacaagccca ataagggtac aggctacaag
    50281 tggttggtga aattggaact ggtcgaggat gccttcaaga cctgcaaaga aggctacaac
    50341 gattactaaa accatagaaa taatagacat gtttaaaatc ctttcataaa taatggctta
    50401 tttgacattg gctttgttaa tcaagtcaaa caaatctttt ttagaatcat ttggtacttt
    50461 acggacatca aattcaacac ccaagtcacg cattttttca aatgtagcaa catcttcttt
    50521 gtccatagac aaaacggtat tgaccaatgt tttacctgtt gagtgagcca tagaaccaac
    50581 gttaagagtc ttgattggca cgccgccttc gatggcacga agggcatctt gaggtgtttc
    50641 aaacaagata agggcatgtg tttctccaaa acgtgggtct tttgaaatct caatcagttt
    50701 ttgaattgga accacgttag ccttgacatt acctggagct gcttgtttaa tcaattcttt
    50761 acgaaggtcg tctttagcca cgttatctga agcaacgatg atacgatttg cttttgaatc
    50821 tggagtccaa gcagttgcaa cctgaccgtg aagtagacgt gtgtcaagac gggcaagatt
    50881 gattttcaat ttaccgtctc cgataacagt tccttctggg atagcagttt gggcaactgg
    50941 agcagctgca gcgcttgcaa cttcttcaac tggatttagc tcttctggaa gagctttgat
    51001 gccatctttg gcttctttaa tgatattagc agcgactttt tctacacctg cagcagcgtc
    51061 catgaggcgc tctgtgtagg cttgaatcaa catcggtaag ttaagtcctg tgatgatggc
    51121 aaacttacgc tcaggatttt ctcccatcac gcgactagct tggttaaatg gagaaccact
    51181 ccaaaggtca gccaaaacta gaacctcatc ttctgcgtca aatgcagcaa cagcgttatt
    51241 aaacttagcg tatagatcat caggaccttc atttggcata aaggtcacaa cttgaacctt
    51301 ttcttgttca ccaaagatca tagatcctga ctgatgaata ccagcagcaa attcgccgtg
    51361 gctcgcaata atgattccga tactcattat tgtcattcct ccttttttgt tttagttttc
    51421 atttaagaaa actttaagac tgtttaagta taaaccgttt tcataaaaaa agcaactatt
    51481 tatcataaaa aattaaaaaa tttttatttt tgtatgttga tatgttgagt ttttgaggag
    51541 taatcttgaa ttcttattta aaatttaata taaaaaagtt ggaagaagct tccaactttt
    51601 aaaataggtt tctattaaat tagtgggtga agtcgagtac catacgtcct tggatttggc
    51661 ctttttccat ttcgtcgaaa atggcaacag catcttctac tggacgtttt tgaacaactg
    51721 ggactaccag accttctgca ccaaattgga aggcttcttc taagtcttta cgagttccga
    51781 caagagaacc gatgacttgg attccatcga ggactgtttt aacgatgctg agttccatca
    51841 tttcagaagg aagaccaaca gcgacgacgc gaccaccagc acgaatggag tcaacagcct
    51901 ggttgaaggc aactttagac acagcagtta cgacagctga atgagctcct ccatcagttt
    51961 tttctttaat gagtccagct acatcttcaa cttcgaggcc gttaatcaca atgtcagcgc
    52021 ctacttcttt tgcaagggta agtttgtcat tgttgatatc gactgcgata acatgagcat
    52081 tgaatacttt tttagcgtat tgaacagcga ggttaccaag tccaccagca ccgtaaagaa
    52141 caacccattg gcctggttca acttttgctt ctttgatagc tttataggtt gttactccag
    52201 cacatgtgat agaagaagct tgggctggat caagtccgtc aggaactttg acagcatagt
    52261 cagcagttgc gatacattgt tcagccatac caccgtctac tgagtagcca gcatttttca
    52321 ctgtacggca aagggtttcg cgaccagttg tacagtattc gcaagtgcca catccttcaa
    52381 agaaccaagc aacgctgacg cggtcaccga ctttaaggct tttcacatct ggagcaatct
    52441 ctttaacgat accgatacct tcgtgcccaa gaacacgtcc tgggacttga ccaaagtcac
    52501 catgagcaac gtggaggtcg gtgtggcaaa cgccacagta ttcaacttct acaagtgctt
    52561 ccccagtttc aagtggacgg agtacttttt cttcaatagc aacaccagtg ctttctggat
    52621 ttacaacaac agctttcata gctatcctcc ttgatattga ccgagaacag ggacaacggg
    52681 actggattga ttttttgtca acagagtcga gtgtgacgag ctctcttgta tttatatgtg
    52741 aagtatatca caaaaggaag ccttttccaa ggttttggag acaaaaagta gaacaatcga
    52801 ttaactggtt gatgagactg tgaaaagagc acaaagacca gcttgcaagc tggtcatact
    52861 cttcgaaaat ctcttcaaac cacgtcagct tcatctacaa cctcaaagca gtgctttgag
    52921 caacctacgg ctagcttcct agtttgctct ttgattctca ttgagtatca gtataggtta
    52981 taagaataag tcttgtaggg ttttggcaac cccatcttgg tcgttggtaa gggaaatttg
    53041 ctcatctgca taagggagta gctctggatt ggcatttttc atggcataac ccttcccagc
    53101 aaaagcgagc atttcggtat cattgtgttc atctccaaag gcaatcaaat cttttttgtc
    53161 acgattcatt atcttgagca agtagtccaa agcaaaggcc ttgttgacac cttttggggt
    53221 acattcaagg atattgagcg gacctcccca ggtattgata gaaagttgat gctggtagaa
    53281 ggcgttcatg tcttttgcca aggcatattt gtcactggct ctggtctgca agaggataca
    53341 gttagggtcc ttggtcacca attcaggctg gaattgatct tcaggctgga aagcttctac
    53401 accaaatagt ttgggattgg caatttcttc attgggattt gtaatgtaga attttttacg
    53461 atattctcca gcgataaaat cggcttgaat gtcctctgaa cgttgaacca tatctagcag
    53521 atattttttg tctacagtca aacacttttc aaaatcccaa acttggtctg gtaaatgagt
    53581 aagggatccg ttgaagttaa tcataggagt gtctaagccc agttcacggt aaaaatcttt
    53641 tgacatacgg taagggcgac ctgtcgtaat aataacctga tggccttttt cagcaacttt
    53701 tttgatggtt tttttggtaa agtcagaaat ttgactgtct gagttgagca gggttccatc
    53761 caggtcaact gcaataattt ttttcgtcat atggaccttt ctagtgtgtt ttcagataag
    53821 atgtcttcta ttataacaga aagcaggcag aaaagcagat tccaaacaaa aaatgaaatt
    53881 ggattaattt cttaaacaaa tcaaacaaag acattgaaaa agtgaatgat aaatgatata
    53941 attctattat tgttcgtaaa aattaaaagg agattgatga tggacaaatt atttaaacta
    54001 aaagagaacg gtacagacgt tcgtacagag gttctcgctg gtttaacaac tttctttgca
    54061 atgagctata ttctctttgt aaacccacaa atactttcac aaacaggaat gcctgctcag
    54121 ggcgtcttcc tagcgacgat tattggtgca gtagcgggta ccttgatgat ggctttttat
    54181 gctaacttac cttatgccca agcgccaggt atgggactca atgccttctt tacctttaca
    54241 gttgtattcg ggcttggtta ttcttggcaa gaagccctag ctatggtctt catctgtggg
    54301 attatttcat tgattattac cttgacaaat gttcgtaaaa tgatcattga atcgattccc
    54361 aatgctcttc gctcagctat ttcagctggt atcggtgtct tccttgccta tgtagggatt
    54421 aagaatgctg gacttttgaa attcacgatt gatccaggca actatactgt tgtaggagaa
    54481 ggggctgaca aagctcaagc aacgattgca gcaaactctt cagcagttcc aggattggtc
    54541 agctttaata atccagctgt tttagtggct cttgcaggac ttgccattac tatcttcttt
    54601 gtcatcaaag ggattaaagg gggaattatt ctctctatct tgacaacaac tgttcttgct
    54661 attgcagttg gtttggttga tttgtctagt atcgattttg ctaataacca tgttggtgca
    54721 gcttttgaag atttgaagac aatctttggt gcagctcttg gttcagaagg tttgggagct
    54781 ttggtttcag atacagctcg cttgcctgaa actctgatgg ccattcttgc cttctcattg
    54841 acagatattt ttgacacaat tggtaccttg atcggtacag gtgaaaaagt tggtatcgta
    54901 gcgacaaatg gtgaaaatca ccaatcagcc aaattggata aggctcttta ctctgatttg
    54961 attggaacga cagtcggtgc cattgcaggt acttcaaacg taacgactta tgttgagtct
    55021 gctgctggta tcggtgcagg tggacgtact ggtttgacag ccttggttgt agctatctgt
    55081 tttgcgattt caagcttctt tagcccactt ctagcgatcg taccaacagc ggctacagct
    55141 ccaatcttga ttatcgttgg gattatgatg cttggtagct tgaaaaatat ccattgggat
    55201 gatatgtctg aagcagttcc tgccttcttc acatctatct ttatgggatt cagctactct
    55261 atcactcaag ggattgcagt tggtttcttg acttacactt tgactaagct tgtcaaaggt
    55321 caagttaaag atgttcatgc catgatttgg attttggatg ccttgtttat ccttaactac
    55381 atcagcatgg ccttataata gaatgaccca gggggatttc cccctttttt taatacaaag
    55441 gagataggtg atgaaagaga aaaatatgtg gaaagaattg ttgaatcgtg caggctggat
    55501 tttggtcttt ttacttgccg tccttttata tcaggttccc ctagtggtta cctctatttt
    55561 gactttaaaa gaagtagccc tgctacagtc agggctgata gttactggcc tttcaattgt
    55621 ggttctggct ctatttatta tgggagctcg taaaaccaag ttagctagtt ttaatttttc
    55681 tttttttaga gctaaagatt tggcacgttt gggcttgagt tatttagtta ttgtcgggtc
    55741 aaatatactt ggttctatct tgttgcaact gtcaaatgag acgacaacag ctaaccagtc
    55801 tcagattaac gatatggttc agaatagttc cttaatttcc agtttcttct tgttggcctt
    55861 gcttgctcca atttgtgagg aaatcttgtg ccgtgggatt gttcctaaaa agattttccg
    55921 aggaaaagag aacttgggat ttgtagtcgg tacggttgtg tttgctttat tgcatcaacc
    55981 aagtaattta ccttctttat tgatttatgg aggtatgtcg atcgttctat cttggacggc
    56041 ttacaagacc caacgtttgg aaatgtctat cttacttcac atgattgtga atggggttgc
    56101 tttctgtttg ttggctctcg tggtgatttt gagtcggaca ttagggatct ctgtttaaga
    56161 tttttgacaa ttgcttactt gtttctactg ggaaaaagat gaatgcaatt gtgtccatct
    56221 ttttcttttt atggtaaaat agagaaataa tatggtgaaa agccttgagg gagtgaccga
    56281 tatgtcaagt aaagccaatc atgcaaagac agctatttgc ggaattatca atgtaacccc
    56341 agactccttt tcggacggtg gtcaattttt tgctcttgag caagcactcc agcaggctcg
    56401 taaattgata gcagaagggg ctagtatgct agatatcggc ggagaatcga ctcggccggg
    56461 aagaagcagc tatgttgaga tagaagagga aatccagcgt gttgttccag taatcaaagc
    56521 tattcgcaag gaaagtaatg tcctcatctc tattgatact tggaagagtc aggtagcaga
    56581 ggctgctttg gctgctggtg ccaatctagt caatgatatc actggtctca tgggtgatga
    56641 aaaaatggcc catgtggttg ctaaggctgg agcgaaagta gtcattatgt ttaatccagt
    56701 catagcacga cctcagcacc ctagctcgct catctttcct cattttggtt ttggtcaagc
    56761 ttttacagaa aaagagttag ctgactttga aacattgcca atagaagact tgatggagac
    56821 tttctttgac agagccttag cgagagcaga ggaagctggt attgcacaag aaaatatctt
    56881 gttggatcca ggaattggct ttggtttgac caagaaagaa aatctgcttc ttttacggga
    56941 tctggataaa ctacatcaga aaggctatcc aatctttctc ggagtgtcgc gcaagcggtt
    57001 tgtcatcaat attcttgaag aaaatggttt tgaagtcaat cctgagacag aacttggttt
    57061 ccgcaatcga gatacggctt cggctcatgt aaccagtatc gctgtgagac agggtgtgga
    57121 agtggtgcgc gtgcatgatg tagctagtca caggatggca gttgaaattg cctccgctat
    57181 tcgtctggct gatgaagcgg aaaatttaga tttaaaacaa tataaataag atgaaagaat
    57241 ttgaaaacaa tcagtggatt gctaactacc ggacggatca accgcatttt ggcttggaac
    57301 gaatggtgga actgttagct ttgcgtggca atccccatct caaactcaag gtcatccata
    57361 tcggagggac taacggcaag ggttcgacca ttgctttttt gaaaaagatg ctagaaaagc
    57421 tagggctgag agttggcgtg tttagctctc cctatctcat tcattacaca gaccagatta
    57481 gcatcaacgg ggaatccatt ccagaggcta ggctagaagc cctcatggca gactaccggt
    57541 ctttgcttga gggggaatcg gctaccaatt tgcaggggac aactgagttt gaaataatta
    57601 cagccatagc ctatgactac tttgccttag agcaagtaga tgtggccatc atggaagttg
    57661 gcatgggtgg acttttggat agtaccaatg tttgccagcc cattttgaca ggcatcacca
    57721 ctattggact ggatcatgtg gccctacttg gtgacacctt ggaggccata gcagagcaga
    57781 aggcaggcat tatcaaacaa ggaactccct tggtgacagg tcgtatcgct ccagaagcct
    57841 tggctgtgat tgaccgcatt gcggaaggga aagatgcgcc gagacttgcc tacgggacag
    57901 attatcaggt tcgtcatcaa gaaagtgtgg tgacagggga agtctttgac tatacaagtg
    57961 ctgtcagaca aggtcgcttc cagactagcc tgcttggttt gtaccaaata gagaatgctg
    58021 ggatggccat agctttactt gatacttttt gtcaagaaga tggtcgagag ctagcaagca
    58081 atgactttct tggtcaagcc ttggaagaaa caagttggcc agggcgtttg gaaatcgtgt
    58141 caagagatcc cttgatgatt ttggatggag cccataatcc ccatgctatc aaggccttgt
    58201 tggtaacctt gcaagaacgt tttgcggatt atcataagga aatcctcttc acttgtatca
    58261 aaaccaaagc cttgggggat atgttggact tgctgggagc tatgccagat accgagctta
    58321 ctctaacaca ttttgcggat agtcgggcga cggatgaaag cgtgctgaaa gaggcagcta
    58381 agtctagaaa tctcagctac caagattggc atgattttct agagcagaat ttgacagata
    58441 aaaaagaaga gaaacaaaca gttaggattg tcacaggttc cttgtatttc ttgagccaag
    58501 tgagggccta tctgatggag aggaagaacg agaatggata cacaaaagat tgaagcagct
    58561 gtaaaaatga ttatcgaggc tgtaggagag aacgctaatc gcgagggctt gcaggaaaca
    58621 cctgctcgtg tagcccgtat gtatcaagag attttttcag gtcttggtca aacagcagag
    58681 gaacatttgt caaaatcctt tgaaattatt gacgataata tggtggtaga aaaggatatc
    58741 tttttccata ccatgtgtga acaccacttc ttgccatttt atggtagagc gcacattgcc
    58801 tacattccag atggtcgtgt ggcaggcttg tctaagctag cccgtacggt tgaagtttat
    58861 tcgaaaaaac cacaaattca agaacgtttg aatatcgaag tggccgatgc cttgatggac
    58921 tatctaggtg ctaaaggagc ctttgttgtc attgaggcgg aacatatgtg tatgagtatg
    58981 cgtggtgtta gaaaaccagg cactgcaacc ttgacgacag tagctcgtgg tctatttgaa
    59041 acagataagg acctccgcga ccaagcttat cgtttaatgg ggctataaaa agaatccgtt
    59101 tcaagcggat ttttctagaa aggaatcatt atggatcaac tgcagattaa ggatttggaa
    59161 atgtttgcct atcatggtct ttttcctagt gagaaagaat tggggcagaa atttgtcgtt
    59221 tcagccatcc tatcctatga tatgaccaag gcagctacag acttggattt aacagcctct
    59281 gtccattacg gagaattgtg tcagcagtgg acgacttggt ttcaggaaac gagtgaagat
    59341 ttgattgaaa cggtagccta taaactggtg gaacgtactt ttgagaccta tcctcttgtc
    59401 caagaaataa agctggaact aaaaaaacct tgggcaccag tgcatttgcc actagatact
    59461 tgctcggtaa ccattcatcg ccgcaagcaa cgagccttta tcgccctagg aagcaatatg
    59521 ggagataaac aagcaaactt ggagcaagcc attgacaaac tgcgagctcg tggcatccat
    59581 attctcaaag agtccagtgt cttagcgacg gagccttggg gtggagtgga gcaggatagc
    59641 tttgctaatc aggtgattga agtagaaacc tggctaccag caccagtctt gttagaaacc
    59701 ttgttagcca ttgagtcaga gatgggacgg gtgagagaag tgcattgggg acctcgtttg
    59761 attgatttgg acttgctctt tgtggaggac cagatccttt atacagatga ccttatcttg
    59821 cctcatcctt acatagcgga acgccttttt gtccttgagt ccttacagga aattgcgtct
    59881 cattttatcc atccgacatt aaagcaaccg atccgcaact tgtataatgc tttgaaaaaa
    59941 taaaaaaact ctagttttca gtcatttgta actgaagact agagttttta aaataggtca
    60001 ttttcttctg ggaggaggat agtttctcta ccatccatgt ctaaaaccag tactcttggc
    60061 ggatatagag ggtcaaaagg atggttaaag tcaaaatcaa tagctgtagg gaggtgttga
    60121 cttgaaaaat ggaaggtaat ttttccttgg ttattgagca attgaaactc aagttcttct
    60181 tccaattcaa agacattttt taagaaatgg tcgataatat accaaaaaga gtcaatgatg
    60241 tcatcaggca agctggtaac aatgccaaaa ctagcagacc gcatgtgggt attggtaaaa
    60301 gccatatctc tgtctccttt cttttccctt atcatacagc aaataggatt aaaaatcaag
    60361 aaaaggtgat tttttgaaaa ggattttaac tacagggaaa aagaaggaaa aaaattccca
    60421 aaaatctacc gaagttaata ggtaaattcc caaattaact tgattatata actttcagtt
    60481 actttgagaa gttaccgaaa aatatttttc atatctattg acttttaggg gtgaaatttg
    60541 gtatgatagt aggcggtatt gtttacccca tttgaaaggc cccggaacct tccaaatact
    60601 tttcgatggg aaggaacacc catcaccgta aacaaaaatc gaactatata taggagaaat
    60661 catgaacaaa acaacattta tggctaaacc aggccaagtt gaacgtaaat ggtacgtagt
    60721 tgacgcaact gatgtaccac ttggacgtct ttctgcagta gttgctagcg tacttcgcgg
    60781 aaaaaacaaa ccaacattta caccacacac tgatacaggt gacttcgtga ttgttatcaa
    60841 tgctgaaaaa gttaaattga ctggtaaaaa agcaactgat aaaatctact acactcactc
    60901 aaaccaccca ggtggattga aacaaatctc tgcaggtgaa cttcgttcta aaaatgcagt
    60961 acgtttgatt gagaaatcag ttaaaggtat gcttccacac aatacacttg gacgcgctca
    61021 aggtatgaag ttgaaagtat ttgttggagc tgagcacact catgctgcac aacaaccaga
    61081 agttcttgac atttcaggac ttatctaagg aaaggaacaa ataaagtatg tcacaagcac
    61141 aatatgcagg tactggacgt cgtaaaaacg ctgttgcacg cgttcgcctt gttccaggaa
    61201 ctggtaaaat cactgttaac aaaaaagatg ttgaagagta catcccacac gctgaccttc
    61261 gtcttgtcat caaccaacca ttcgcagtta cttcaactgt aggttcatac gacgttttcg
    61321 ttaacgttgt aggtggtgga tacgctggtc aatcaggagc tatccgtcac ggtatcgctc
    61381 gtgcccttct tcaagtagac ccagacttcc gcgattcatt gaaacgcgca ggacttctta
    61441 cacgtgactc acgtaaagtt gaacgtaaga aaccaggtct taagaaagct cgtaaagcat
    61501 cacaatttag taaacgttaa ttcgaaagaa ttactatact tatacagagc acctttcggg
    61561 gtgttctttt tttatacttt cttactaaat tggtgcaatt gacacagttg ttgcgacttt
    61621 agtcgcttac aaatgtggct gcaacctgac aaggtcagtt gcctcaaaac gttaatcaat
    61681 acaattatat caacgtttca aagcactcaa gagtttacct catgggtgct ttttttatgt
    61741 tttttgaaaa agttcacctc aaagtttacc ttattttcac cttattgttt tagagactgt
    61801 aaggcaaatt caccgacggc catagggact acattagaag tattgacata aatctgtgtt
    61861 gtacctgtgt cgctatgtat tagagcttca gaaatggctt ctaagctcat tcctgcttgt
    61921 ttagcgagcg ttgctccggt atgacgtagt ttgtgtggcg tagcgtgtgt aagctctggg
    61981 tgtcgttttc tgatagtttt catcttatta ttgagatagt cagaatgtaa aggtttattg
    62041 atattgcctt tggtatctat gtaagtaaag atgaattgtt ctggattact gatgatacca
    62101 aactttgcca gttcatattt ttgttgtttt ttccatgaag tcagaagttg aagtaagtca
    62161 ttagaaatag agaaaatggg aaatgtttcc acaataaaac gcatattatc agatggttaa
    62221 tgcgttttat atttgggttt gaggcttata aaataggata agcgtactga aaacttagat
    62281 atgacaaaca aaataaaatt tttaaaagct acagagaaac atggtataat gtatctaaag
    62341 gaggtagcat atgtccttag atatagataa agaaaagatg acaatcatgg gaatagcttt
    62401 tgaaaaccga tccgttttta agagtgtttg gtatgcttta agtacaaata tgattgaagg
    62461 atggcgacct acggttagtg atgttgaaaa attacgagat gaagctcttg ctctggggat
    62521 gacttaatga agcgcaactg ttatgagtct tatgactatg ttgatccgga taatttatat
    62581 accgatccgg gttcttcagt tctaagaaat aagcaggaag gaaaaaagca cgcgagcttg
    62641 aatatcgtat gattgctagt aagagtttga aattatttat caatcctatc ttagttaata
    62701 gtttaaaagt agtttgtttc acaactgcat aagcttagaa aagttgaaaa gtgataactc
    62761 tttaataaac tcttggtttg ttaaaagata ttttgtccac tacatttttt tcaattgact
    62821 attatttgtc atagatataa cagatagaac attgcattca gaataatgaa aaacgcatca
    62881 aaaatggtgc gttctgtttt tatgctacca taaaaggagg aaaacaaatt gaaaattttt
    62941 aagggagagt tttatcgaat ctctgtatta acagacaagc tagtaaggtt agaatactct
    63001 caaactggaa attttgagga tagaacgaca caacttatct ataatagaga ttttggccaa
    63061 gtttcgttag attatatcga gacatcaaat gtactagata ttatgacgga ctattttcat
    63121 ctgcacttta ataaaggaga atttaacgcc gaaaatttat ttatagaatt aaaaggaaat
    63181 tttgccgtat atggtagtcg ctggtatttt ggtgaatcta ttgaaacgtt aaaaggaaca
    63241 gctcggactc tggataaggc agatggagca atctcgttag aagatggaat tattagccga
    63301 aatggtatag ccttattgga tgattctcaa ggatttattt gggatgaaca atctggttat
    63361 attgagagag aaaatcaaat tgacctgtat ttctttgctt atgggcatga ttatagagga
    63421 gcaatcagag acttttacca tttgactggt tcaacaccct tgttgccaag atatgcttta
    63481 ggcaattggt ggagtagata ttggccttat acgtcggatg aatacttgga tttaatagac
    63541 agatttgaaa cagagaaaat tccattatct atcggtgtgt tagatatgga ttggcatata
    63601 actgacattc cagctcgttt tggaagtggc tggacaggat atagttggaa tagaaactta
    63661 ataccaaatc cagaacagtt attgcaacaa cttcatgata gaaagttaaa actctcctta
    63721 aatgtccatc ctgctgatgg gatacgggct tatgaagaag cttatcctca aatcgcaaaa
    63781 cgattggggt taaatgtaga actagaagaa cctgctattt ttgatttttt taatccctct
    63841 tttagggaag cctactttaa agatgttcat tatgagctag aaaagcaggg agtagatttt
    63901 tggtggattg actggcaaca agggacacaa ggtatgctag atccactttg gcttttaaac
    63961 cattatcact atcaggatag ttgtaaaaat gcagaaggtg gtttgatttt atcaagatat
    64021 gcaggtcctg gtagtcactg ctaccctgtt ggtttttcag gggatactat tattagttgg
    64081 aattccttaa gatttcaacc ctattttaca gcgacagcat ctaatatcgg ttatagttgg
    64141 tggagtcatg atatcggtgg acatatgttg ggggattatg acgaagagct acaaactaga
    64201 tggctacagt ttggtgtttt tagtccgatt actcgattac atagttctag aagtcctttt
    64261 aatagtaaag aaccttggtt tttttcagaa acaacatcta agattatgaa gaaatacctt
    64321 cgtttgagac atcagatgat tccttatcta tataccatga atgtaaagac acatgaggaa
    64381 ggtgccccat taatcagtcc aatctattat ttctatccag agaatgatga gagctataat
    64441 gttccaaacc aatacttttt tggaacagaa ctgatggtgg ctcccattgt agaaaagatg
    64501 gatttgacat tccaatctgc aaaagtagat gtatggttcc ctgaaggtga atggtatgac
    64561 ttcttttcag agaaaaaata cacaggtggt gtgaagttaa gtgtttatag ggacatctcg
    64621 actacgcctg tgtttgcaaa aagtggtgca atcattccct tggttggttc tgagataggt
    64681 atgggtgttg atttacctga ggttgtagat tggtatgtat tcccagggaa acaacattct
    64741 tttgaaatgc ttgaagatca aaatggtcaa agatataaaa caagattatc aatcgattgg
    64801 gaaatgggaa tggtagagtt agcattacaa ggagattcta gtatcgttcc aagcaataga
    64861 aaacatagaa ttcattttaa aggaacgaat gtgtctataa ttgaattgcc aaataagaat
    64921 gatacagcta aatttgaatg gaaagataat aaaaggacat ctttaaatga cgaagttttt
    64981 agactactaa agacagcttc tcttccatat gaattaaaag atagattgtt aaatcaattc
    65041 atcaatgcga aaaactctca tgacttaatg aatatcttgc atcatcagga taaggaattg
    65101 agagggcgtt tgttggaaat gatatttact agccaaaact aattgaaata attagaaagt
    65161 catttgttta gtgtatatga agattctgta tggtattcgt tatcactggt cacattgaaa
    65221 atgtgaaata agcacctaca acatagactt tacaacactt catgtttcat atcatggggt
    65281 gtttttctat ttaagtcaaa gccaatcaaa aaatctcact attcatcagg ttaaaggaaa
    65341 cctaatcata gtgagattgt gaattatagt agagtttgta tcgcctcttc aatttgtttt
    65401 gggtctgttt ttgaagaaaa gcgttcaaag acttgcccat ctcgaccgat gagaaactta
    65461 gcgaaattcc attcgattcg ttttcctagt gggccagatt tctggtcttg taaccagaca
    65521 tagagagggt ctgcttcctt accgttgacc ttaatcttgg caaaacgtgg gaaggtggtt
    65581 tgaaaatgta ggctacagaa ggcgttgatt tcctctgcgc tgccgggtgc ttgtcccata
    65641 aactgattgc aagggaaatc caatatttca aagccctgat cttgatagcg ttcatagagt
    65701 tcttgaagtc cctggtactg gggcgttaaa ccacatccag tagcagtgtt gacaatcaag
    65761 agaactttgc cacgatagct atccaaggga gttgcttggt tgttttggtt caaaaaggaa
    65821 aaatcataaa gtgaagtcat gagggcctct tttctttttc tacattgtaa cagtttttac
    65881 ttttttcgtc gagtcggatg gaagatattg ttgaagaata agccctcaat atgatagaaa
    65941 ccgtttacaa ataactttaa aaatggtatg atttaattaa accgatttac ttagttgcta
    66001 taaatctcta atttgagatt tagttcctat tgattttaca atatgtttat tggagtgtat
    66061 acatgcaaac aaaaacaaag aagctcattg tgagtttgtc ttcacttgtt ttatcaggat
    66121 ttttattaaa ccattatatg acagttggag cggaagaaac gactacgaat actattcagc
    66181 aaagccagaa ggaagttcag tatcagtaaa gggatacaaa aaatttagtt gaaaatggtg
    66241 attttggtca gacggaggac ggaagcagtc cgtggacagg aagcaaagct caggggtggt
    66301 cagcttgggt agaccagaag aatagttctg cagatgcctc aactcgagtc attgaggcta
    66361 aggatggggc tatcactatc tcaagccctg agaaattaag ggcagcggtt caccgtatgg
    66421 ttcctattga agctaagaaa aagtataaac tgcgtttcaa gattaaaaca gataataaag
    66481 tcgggattgc caaagttcgt atcattgagg aaagtggtaa ggacaagcga ttgtggaatt
    66541 ctgcaacgac gtcaggaaca aaggactggc agaccattga agcagactat agcccgactt
    66601 tagatgttga taaaatcaag ctggagttat tctatgaaac aggaactggg actgtttcct
    66661 ttaaggatat tgagctggta gaggtagcag accagctttc tgaggattct caaacagata
    66721 aacagcttga ggaaaagatt gatttaccaa ttggaaaaaa acatgttttt tctcttgcgg
    66781 actatactta taaggtagaa aatcctgacg ttgcttcagt caaaaatgga attttagaac
    66841 ctcttaagga agggacaacc aatgtcattg tcagtaaaga tggcaaggaa gtgaaaaaga
    66901 ttcctttgaa gattctagcc tctgttaagg atgcatacac agcccgtttg gatgactgga
    66961 ctggcatcat cgctgggaat caatactatg attctaaaaa tgaacagatg gccaaattaa
    67021 accaggaatt ggaaggaaag gtagctgata gcctatctag tatttcaagt caggcggacc
    67081 gcacctattt gtgggaaaaa ttttcaaatt ataaaatgtc tgcaaatctg actgccactt
    67141 atcggaaatt ggaggagatg gccaagcaag tgaccaatcc ttcttctcgt tattatcaag
    67201 atgaaactgt cgttcgaaca gtcagggatt ccatggaatg gatgcataaa catgtctaca
    67261 atagtgaaaa gagcattgtt gggaactggt gggattatga aatcggtaca cctcgtgcca
    67321 tcaacaatac cttgtctctg atgaaagaat acttctctga tgaggaaatt aaaaaatata
    67381 cagatgtgat tgaaaaattt gtaccagatc ccgaacattt ccgaaagacg actgataacc
    67441 catttaaggc tctaggtgga aacttagttg atatgggaag ggtaaaagta atagctggtt
    67501 tactgcgtaa ggatgatcaa gaaatttctt ctaccattcg ctcgattgag caagtgttca
    67561 agttggtaga ccaaggtgaa ggtttttatc aagatggatc ctatatcgac cacaccaatg
    67621 ttgcctatac gggtgcttat gggaatgttt tgattgatgg cctgtctcaa ctgttgccag
    67681 tcattcaaaa gaccaagaat ccaatcgata aagataaaat gcaaaccatg taccactgga
    67741 ttgataaatc gtttgctcct ttgctggtga atggagagct gatggatatg agtcgtggac
    67801 gctcgatcag tcgtgcaaat agcgaggggc acgtggccgc agtagaagta ctaagaggga
    67861 ttcaccgaat agcggatatg tctgaaggag aaaccaaaca acgtttgcag agtcttgtga
    67921 agaccattgt tcaatcggat agttattatg atgtctttaa gaatttgaag acttataagg
    67981 atatcagttt gatgcaatcc ttgttaagtg atgcaggagt cgcaagtgtt ccaagaacaa
    68041 gttacctatc tgcctttaac aagatggata aaacagccat gtacaatgca gagaaagggt
    68101 ttggatttgg cttgtcactc ttttccagtc gtaccttgaa ttacgaacac atgaacaagg
    68161 aaaataaacg tggttggtat acgagtgatg tgatgttcta tctttacaat ggcgatttga
    68221 gtcactatag cgatggctac tggccaacag tcaatccata taagatgcct ggtacaacag
    68281 agacggatgc tgagagagcg gatagcgata caggtaaagt tctaccgtct gctttcgttg
    68341 gaacgagcaa actagatgat gccaatgcga cagcaaccat ggatttcacc aactggaatc
    68401 aaacattgac tgctcataag agctggttta tgctgaagga taagatcgcc tttttaggaa
    68461 gcaatatcca aaacacttca acagatactg ctgcaactac aattgaccag agaaaactgg
    68521 aatcaagtaa tccatataaa gtctatgtca atgataaaga agcctccctt acagaacaag
    68581 aaaaggatta tcctgaaacc caaagtgtct ttttagaatc gtccgattcg aaaaagaata
    68641 ttggttactt tttctttaag aagagttcaa tcagtatgag taaggctttg caaaagggag
    68701 cctggaagga tatcaatgaa ggacagtcag acaaggaagt tgaaaatgaa tttcttacga
    68761 ttagtcagga tcataagcaa aatggagatt cttatggcta tatgctcatc cctaacgtgg
    68821 atcgtgccac cttcaatcaa atgataaaag agttagaaag tagcctcatc gaaaataacg
    68881 aaacccttca gtctgtttat gatgccaaac aaggagtttg gggcattgtg aaatatgatg
    68941 attctgtctc tactatttcc aaccaattcc aagttttgaa acgtggagtc tataccattc
    69001 gaaaagaagg ggatgaatat aagattgcct actataatcc tgaaacccag gaatcagctc
    69061 cagatcagga agtctttaaa aagctagagt aagcagctca gccacaagta cagaattcaa
    69121 aagaaaagga aaaatctgaa gaggaaaaga accattcgga tcaaaagaat ctccctcaga
    69181 caggagaagg tcagtcaatc ttggcaagtc tagggttctt gctacttggg gcgttttatc
    69241 tattccgtag aggaaagaac aactaatttg ttcatcatct agatgaatta catgaaactg
    69301 tggaaaatag aaaaaatccg aagaaggcca aatatcttcg gatttttctt ttaaaaaggg
    69361 ataagttgat acttatcctt ttttacttca ttatgtgact atagcgtttt gaaactagaa
    69421 tagtacgtca taactgctaa aagatttcta taaattcatt tgattttcct aatcaatttg
    69481 ttcgtatcct atttcactcc actatattag tccgtctcgc tccgtgaggt gcgagacaaa
    69541 acaaccaccc gctatgcggg tgcgcgtcga aggttatacc aaaaaaactc caaacgcgat
    69601 acaataaagg tgttcaatcc aattgtaaag cgaaaggaga aaaaatatgg cacaaaaggc
    69661 tcatagttta tctcacacaa agtggaggtg ttctatcaca ttgtgttcac ccctaagtat
    69721 agacgaaaag tcatctataa tcaatataga agtagtttag gcgaaatatt tcatcgcttg
    69781 tgtagttata aaggtgttga aatgatcgag ggtcacttaa tgccagacca tgtacacatg
    69841 ttagtcagta ttccactaag gctaagtgtt tcgagtttca tgggttattt aaaaggcaaa
    69901 agtgcactca tgatgtttga caaacacgcc aatctcaagt acaagtttgg gaatcggcat
    69961 ttctgggtgg aaggttatta tgtaagtaca gtagggctta ataaagccac aattaagaaa
    70021 tatagtcaag attaaagaaa ttatccagtg gatgatttct tcacgagtat gaaaatttga
    70081 gaacgagtaa agcatgatat atagtaaaat gaaataagaa cagaacaaat cgatcaggac
    70141 agtcaaatcg atttttaaca atgttttaga agtagaggtg tactatttta gtttcaatct
    70201 actatagcac tagataaatt gagtgtaaaa gaatatgagg atccctttag ggatagtggt
    70261 aagtaatacc aaagtctctt aaagaggcaa gtgacgagtc aagagcaata aggcttgaac
    70321 aacgtgaaag ccagcgtctt taggcgctgg ctggtaattt gggcttatag ctctgggata
    70381 aaccacctgt ttgacgggtg gttatgattt tatctgagtg taacatactg ttgggcaatc
    70441 tcgctgatgc ggtcaaagtt gccttgggaa gcgagtttat tgagttcgcc accaattcca
    70501 acggcgtctg caccagcagc gaaccattga gggatgttgt ttagaccgac tcctccggtt
    70561 accattacgg aaacttgtgg gatcggtgcc ttgactgcag agatatatgc tggactgaga
    70621 gcactacctg ggaagagttt gatgatttca ctaccggctt caagtgcagt cgtgatctct
    70681 gtgagggtaa tacagcctgg aatgtacggt gtgctgtaga gattgcacat tttcgcagtt
    70741 tcagcatgga aagatggaga aacaacgtaa tttgctccgg ctagaatggc atctctagca
    70801 gttacggcat caagcacagt acctgcaccg atacaaacac tctgatcgtc ctgatacaag
    70861 tctacaagtt ccttgatgat ttgtcctgca tacggattgg tataggcgat ttcaatagct
    70921 ttgataccgc ccttgataca agcaatcgag gcttgcagtc cttcttcctt tgtattccct
    70981 cgaatgacag cgacaatttt ctgttttttt agttcaataa tcgtatctga tttggtcatg
    71041 taattctcct aacgaatgat atcttgtgca tttgccagta aattttcaat actagttgcg
    71101 gaagtggaga gatggtctcc tggaagagtg catttgagag ttgcgctcgc aactgcaaag
    71161 tcaatggtag tttttaggga ggaatgatgg agtagttggt aaagggcacc agatataaag
    71221 gcatccccgc taccaattcg ttgatagact gcagttttta gttggacaga ctcttcaaat
    71281 cgttcttcca gagcataggc ttgatagaca tttttgtctt gctcatcact agagcggagg
    71341 gtatggaaaa tggccttgaa accataggct tcttttaaaa gtcgcatgcg attttccacc
    71401 tcttctaggc tagcactgtc tcttggaaac atctctagat tttggtcatc aatcatgaga
    71461 ggatcaatac cgaagcaata gtcagtaaaa cgtacaaact tagaaaattc atacttggct
    71521 tctagaactg aaatcatctt tgttctcaga ttgagatcca ttgaaacgac aattcctcgg
    71581 cgcttggctt cttccaagag taggagaagg atcgtacgga cctcttgacc gatagctacg
    71641 gtgattccac taaaatgaaa atggctaatc ccctgaaaga gagaatccat atctagcatg
    71701 tttggccgaa tctggctgat actcgtatgc ttacgatcgt agaaaacttc actttgacga
    71761 caaccaaagc cgttctccaa atagtagagg ccgattcgat agccaagccg acagattgaa
    71821 ctggtatcga tttggtgctg tttcaagaat gtgagaaaac gatctccaat ctcgttggca
    71881 gggagtgcgg taaagacttt cgttgagata cccagggctt gcaaattaca agcgatgtta
    71941 atttctgatc cgccaaaata agtcgaactg gcaacatgat ctccgatact ggtggcatct
    72001 aatggtgaga ttcgaattaa tggttcgcca aacagtaata ttttcgtcat ccattagttc
    72061 ctttctggtt tagaatggct ttacttggct aatacttctt tcaaataagc agcgacttca
    72121 tcatcttggc agttttcaaa gaagtattct tggaagtatt tgccagagat ggtgtctttg
    72181 aggaagtctt ggtcgattgt tttaaggatg gtcatcaaat cattgtgggt gatttgtttc
    72241 acctcgttta agatacgagc gttgcgttgt tcagggacta cacgttctct tgggtagcca
    72301 ccgcccattt cttcagcaaa taagcgttca aacattaatt tgagggtcag ttctgccccc
    72361 cagccaaatc ctttggcata agggatagac aaggcgttac caccattgat ttgagaataa
    72421 aggtaagcgt cagttgggtc cactgctaga ccacagacaa caccagggaa gctgtttaaa
    72481 gcaagcatag ctcctacacc cgtaccacag ccggtaacaa caaagtcgac tgcttttgta
    72541 tttaaaagga tggcagccat taggccgttt tgtacgtatg ttaatgggtt ttcaccttct
    72601 tctccacgca taccatagtt aaataattgg tagccttttt tatctgtcgc ttcttttaga
    72661 ctatcgtaaa taatgtgatt cttgctagct tgactatttt cattgattaa tgcgattttc
    72721 ataagatctt ctttctattt ttactcaggt tgttttccga tgtaggctaa gataccgcca
    72781 tctacatata ggatgtggcc attgacaaag tcgctggcat cactagcgag aaagacagca
    72841 gggcccatta aatcttcagg atttccccaa cgtgcagcag gtgtttttgc aatgatgaac
    72901 tggtcaaatg ggtggcgaga accatcttct tgcaactcac gaagaggtgc tgtttgagga
    72961 gtggcaatat aacccggtcc gattccgtta cattggatat tggctccacc gtattcagac
    73021 gcaatattgc gggtcaacat tttcaagccg cctttagcgg cagcataagc gctaaccgtt
    73081 tcacgtccca gttcgctcat catcgagcaa atattgataa tctttccatg ccctttcttt
    73141 atcatagaag gaatgactgc ttttgaaacg ataaatggtg cgtttaagtc aatatcgatg
    73201 accttacgga aatcagcggc gctcatttcg cacattggaa cgcggcggat aataccagcg
    73261 ttattaacga ggatgtcaat gacaccaacc tcttgttcga tttgcttgac catggcttgg
    73321 ataccgtcct cgtctgtcac gtcacagaca tacccatggg cttcgatgcc aacttcacga
    73381 taagcttcaa tccctttatt gaccaggtct tgattgatat cattaaagac aatagtagcg
    73441 ccgacctcag cgtaggattt ggcaatagca aatccaattc cataagaagc gccggtgatg
    73501 agagcaattt ttccttttaa agaaaactgt tcaattgaga atgatgtatt tgtcatttga
    73561 tacttccttt caaatttgtt aagacttctc tataaccaaa ttatattcta gtaaaccggt
    73621 tttgtcaatg attaaatatt tttatttctg aaaatctttg ttttcctaaa aaaacggaag
    73681 attttgaagt ttctgtctat tgtaatggtt aaataagcaa tgaaagcgct aatatttttt
    73741 tgaaaaaact attgacaaga taaaaataaa ggtctacaat gtaaaatata gagtaaaccg
    73801 gtaaactcaa aaagaaagga gaaaagatga aaattgtact tgtagggcat ggacattttg
    73861 ccacagggat ttatagttct ttacaattga ttgcaggcaa tcaagaaaat gtggaggcga
    73921 ttgactttgt ggaaggaatg tcagcagatg aactcaagca aaaaatctta cttgcaattt
    73981 caaatgaaga agaagtttta atcctaagtg atctcttggg aggatcgcca ttcaaggttt
    74041 cttctaccat aatgggagaa aatccagcca aaacaatgaa tgttctctcg ggtttgaact
    74101 tagccatgtt aatggaagca gtctttgcta gaatggctca tagctttgat gaggttgtta
    74161 ataaatcagt agtggcggct cagggcggag tcgtaaatgg taaagaattg ttttcaacgg
    74221 atgcagagga agaggaagaa gatttcgaat cgggtattta aagggtaaaa gaatgataaa
    74281 aaaggttacg attgaagaaa taaaatcgcc tgagcgcttc ttagaagtac cacttctgac
    74341 gaaagaagaa gtcgaccagg caatcgataa ggttattcgg cagttagaac tcaaccttga
    74401 ctatttcaag gaagatttcc cgacgccagc tacctttgat aatgtctatc caatcatgga
    74461 taatacggaa tggaccaatg gtttctggac aggagaactg tggttggctt atgaatacag
    74521 tcaacaggat gaatttaaaa acatcgctca taaaaatgtt ctttctttcc tggatcgtgt
    74581 caataagaga gtagaattgg atcaccatga tctcggcttc ttgtacacac cgtcttgtat
    74641 ggctgaatat aagataaatg gagatggaga ggccagagag gcagccttga aagctgcaga
    74701 taagttgatt gaacgctatc aagaaaaagg tggttttatt caagcttggg gagacttggg
    74761 caagaaagag cattaccgtt tgattatcga ctgcttgctc aacatccaac tcttattctt
    74821 tgcttatcaa gaaacaggcg atcaaaaata ctacgatatt gcagaaagcc atttctatgt
    74881 ttcagctaat aatgtaatcc gtgatgacgc ttcgtccttc cacaccttct actttgatcc
    74941 tgagacaggt caacccctta aaggtgtaac gagacaaggg tatagtgatg attcatgctg
    75001 ggcacgtggt caatcatggg gagtctatgg tattcctttg acttatcgtc acctgaaaga
    75061 cgagtcctgc tttgacttgt ttaagggtgt aaccaattat ttcttgaatc gtctgccaaa
    75121 agatcatgtt tcttattggg atttgatttt taatgatggt agtgatcaat cacgagattc
    75181 ttcagcaaca gctatcgctg tctgtgggat tcatgaaatg ctaaaacatc tcccagaggt
    75241 ggatgctgac aaagatattt ataaacatgc tatgcatgcc atgcttcgtt ctttgatcga
    75301 acattatgca aatgatcaat ttacccctgg tgggacaagt ctcctccacg gtgtgtactc
    75361 atggcattca ggtaaaggag tggacgaagg caatatctgg ggtgactact attacctaga
    75421 agcccttatc cgtttctaca aggattggaa cctatattgg taggaggaga aatatgacaa
    75481 tgccaaatat tattatgacc cgtatcgatg aacggttgat tcatgggcaa ggacaacttt
    75541 gggtaaaata cctaggttgt aatacggtca ttgttgccaa tgatgaagta agcacggaca
    75601 agatgcaaca aactctgatg aaaacagttg taccagactc agttgccatg cgtttcttcc
    75661 ctttgcaaaa ggtgattgat atcattcaca aggctaatcc tgctcaaacg atctttatcg
    75721 ttgtaaagga tgtaaaggac gctttaacct tggtagaagg tggtgtccct atcaaagaaa
    75781 tcaatattgg gaacattcac aatgcccctg gtaaagagca agtgacacgc tctatcttcc
    75841 tgggtggaga ggacaaggca gctctcaagg aattgaacca aacttatcaa gtaacattta
    75901 atacgaaaac aactccaaca ggaaatgatg gagctgttga agtcaacatt atggactata
    75961 tttaaaagag gagatcgtta tgtcgattaa tgtatttcaa gcgattttaa ttggattatg
    76021 gacagctttc tgttttagtg gaatgctgtt aggaatttac accaatagat gcattgttct
    76081 gtcatttggt gtcggaatta ttctaggtga tttgcctact gctcttgcaa tgggagctat
    76141 tggtgaattg gcttatatgg gattcggtgt tggtgctgga ggtactgttc caccaaaccc
    76201 aatcggacct ggtatctttg gtaccttgat ggctatcact agtgctggta aagtcagtcc
    76261 agaagcggct cttgccctct ctactccgat tgctgtggcg attcaattct tacaaacttt
    76321 cgcctacact gtacgtgctg gtgcgcctga aacggcgatg aagcacttga aaaaccataa
    76381 tttgaagaaa ttcaagttca ctctaaatgc aacaatttgg ttatttgcct ttattggatt
    76441 taccttgggt tgcttgggtg ccctttcaat ggataccttg ttgaaactcg tagactacat
    76501 tccaccggta ttgcttacag gtttgacagt tgctggtaaa atgctcccag ctatcggttt
    76561 tgcgatgatc ttgtcagtga tggctaagaa agagttgatt ccctttgtct tgttgggata
    76621 tgtttgtgca gcttatctaa acatcccaac aattggtatt gcaattgtag gtactatctt
    76681 tgctttgatt gaattttata acaagccaaa aacagcgaat catgtggtag aggaggaagc
    76741 acacgatgac tggatctaac aaattaacaa aacgtgatta tcttaaaacg tctttgcggg
    76801 cattcttttg tcaaaatgga tttaactata gtaactatca agggttggga tatgccaatg
    76861 tgatgtatcc tgctttgaaa aaacactatg gagaggatca ggaaggtttc taccaagcct
    76921 tggaagaaaa ctgtgaattc tataatacca acccacactt cctgcctttt attaccagtt
    76981 tgcaccttgt aatgttggaa aatggccgtc cggcaaaaga gacacgtagc atcaagatgg
    77041 ccttgatggg gccattggca ggtattgggg attctctttc tcaattctgt ttagctccat
    77101 tgttctcaac catcgccgct tcttttgctc aagaaggcct ggttgtcggt ccaatcttgt
    77161 tcttcctagc gatgaatacg attttgacag cgattaaatt gtcaactggt ctctatggat
    77221 acaaactagg aacgactgtg attgataaac taagtgaaca gatggcaacg atttctcgta
    77281 ttgctaatat tatcggtgta accgtaattg ctggtttggc agcgacatct gtgaagatta
    77341 tggtgccaat cacctttgct gcaggggaag ttaaagcaga taccaaacaa agtatcgtaa
    77401 gtattcaggg aatgcttgat aaggttgctc cagctcttct accagcccta tttacacttt
    77461 tagtttacta cttgatcaaa gaaaagaaat ggacaacata taaactcgtt attttaacag
    77521 ttatcatcgg aattatcgga agctggctta agattctagc ttaatggata caacattgtt
    77581 ttatggaata gtgattgtct tggcagtgag ccccctttta ctgtcaagct ttcattctat
    77641 tcgtcagcaa aagttgcttc gcaaacagat ggagcaacga aaagagtatt tagcttcttt
    77701 aacatctggt gatgaagtgt tgttattgtc tggaattcat ggaaaaatca tttctatcaa
    77761 agatgacttg gtctccttgc agattgcaaa aggtgtggtc atctatgtag aaaaggaaag
    77821 tgtaatggga aagacaaaag aactgctttt taagtagttc tttttctggt aatagataat
    77881 gaaagaagaa agaagacaat tttttgaaaa aattgatggg gatcaatatc gtgattatat
    77941 cttgtcccac tgttcacaag actatgagaa agtcaagcgt tcccttgaac gcttgatgga
    78001 caatcgtttt atgtttgata gtccttggga tatggaacct tgttcaaaaa tccatcaaat
    78061 ccagccgatg gtgtggaatc aagtatttga agatgatcca gaatgggctt atatgctcaa
    78121 tcgacaagaa tatctcttgc agtttatgat agggtacctg gtagaaggag ataagggcta
    78181 tatccaaaag tgcaagttct ttctatttga ttggattgag caggtgagag aatttcgtcc
    78241 tcaatctttg atgactagaa ccttggatac gggtattcgt tcctttactt ggttgaaact
    78301 actcttgctc ctcttgaaat ttgacctgct agaggaggaa gaactagaga acattttggt
    78361 cagtctagaa aagcagattg actttatgaa aagccattat cgcgccaagt acacccttag
    78421 taactgggga attttacaaa cgattccgat acttgcaacc tatcatttct tttcagataa
    78481 gatggaccta gaagaagctt accattttgc ttcaaaggag ttgaaacagc agatcgagac
    78541 gcagatttta gaggatggaa gtcagtttga acagtcgatt ctctatcatg tagaggttta
    78601 taaagccttg ctggacttgt gtctcttgct tccggacttg caagatagct ttcaagagct
    78661 gctggaaaag atggcgactt acattcaaat gatgacaggt ctagatggac ggaccttggc
    78721 ttttggtgat agcgattcta cagaaacgac agagattttg agcctgtctg ctatggtttt
    78781 gaacaaggaa gaccttctta acggtctgga tgttaaagtc gatttactta gcctcctgtt
    78841 cctggggcga gaaaaggtca agcgactgca ggaatttgaa aagagagctt ggcagcctaa
    78901 gttcaggagc tttgaagatt ctgggcatgt ttgcattaag gatgaacatc gttatctatt
    78961 ttttaaaaac ggtccgctgg gaagtgccca tagccatagt gacgagaata gtttttgctt
    79021 acagtatcaa ggccaaccga ttttcataga tactgggcgt tattcttatc gggaggtaga
    79081 tgaacgttat ctcttaaaga gtgcttggag tcattcgacc tgtatagtag atgggaaagc
    79141 tccagaaagg atcgtgggat cctgggaata tgaatactat cctcactccc tgttttgtca
    79201 ccacaaagaa agagagggag tgcattatat tgagggggcg tatttgtcag cagaacctga
    79261 tttgccttat cttcacagga gaaaaatcct catgttggca gaggatgtat ggctcttggt
    79321 agatgatatc aggtgtcaag gtcagcatga ggcgttgact cagtttatcc ttgacaagga
    79381 tgtgacctat caagatggga aaatcaatca gttgaaacta tggagtgaag ttgattttga
    79441 tttggaagct acgatcattt ctcctaaata caacgagctt gaaaaaagta gcaaactcat
    79501 caaacaccaa ttctttgaga atcagatgct ggattataca atcattgcgc atgagagttt
    79561 tgaaatcatc cgtcattctg tctaccagac agatggtcat caagtagaaa atgctctggc
    79621 ttttgaagtg aaaaatgacg aaacagacaa gctgattctg ttattaagcg aggatatttg
    79681 tgtaggtgaa aaattatgcc tcgttgacgg aacaaaaatg cgtggaaaat gtctagtata
    79741 tgataaaata aatgagagaa tgattcgctt gcagtgctag aaatagacgt tttgaatagt
    79801 gaatatgtta taatgggtat tagtaggagg tgttttagat tggagaagaa actgaccata
    79861 aaagatattg cagaaatggc tcagacctcg aaaacaaccg tgtcatttta cctaaacggg
    79921 aaatatgaaa aaatgtccca agagacacgt gaaaagatta aaaaagttat tcatgaaaca
    79981 aattacaaac cgagcattgt tgcgcgtagc ttaaactcca aacgaacaaa attaattggt
    80041 gttttgattg gtgatattac caacagtttc tcaacccaaa ttgttaaggg aattgaggat
    80101 atcgccagcc agaatggcta ccaggtaatg ataggaaata gtaactacag ccaagagagt
    80161 gaggacaggt atattgaaag catgcttctc ttgggagtag acggctttat tattcagcct
    80221 acctctaatt tccgaaaata ttctcgtatc atcgatgaga aaaagaagaa aatggtcttt
    80281 tttgatagtc ggctctatga acaccggact agctgggtca aaaccaataa ctatgatgcc
    80341 gtttatgata tgacccagtc ctgtatcgaa aaaggttatg agcattttct cttgattaca
    80401 gcggatacga gtcgtttgag tactcggatt gagcgggcaa gtggttttgt ggatgcttta
    80461 acagatgcta atatgcgcca cgctaggcta accattgaag ataagcatac gaatttggaa
    80521 caaattaagg aatttttaca aaaagaaatc aatcccgatg aaaaaactct ggtatttgtt
    80581 cctaactgtt gggccctacc tccagtcttt accgttatca aagagttgaa ttataacttg
    80641 ccacaagttg ggttgattgg ttttgacaat acggagtgga cttgcttttc ttctccaagt
    80701 gtttcgacgt tggttcagcc cgcctttgaa gaaggacaac aggctacaaa gattttgatt
    80761 gaccagattg aaggcctcaa tcaagaagaa aggcaacaag tcttggattg tagtgtgagt
    80821 tggaaagagt cgactttcta agatgaaagg gaaataactg gcaacctctg ttaagaaata
    80881 aaataatccc atctagcatg aactggatgg gattatttgt ctataaaatg agaaattacg
    80941 ggagtaatct cctaaatcaa ctgtttttga tttacttctt taactacttg ataaaagtta
    81001 tagaagtaga ccaaacttga gatgatggtt acgactagga atattggaaa tttccattgg
    81061 atggagtttc ttgattgtct tggttcaaga ctgaaaaatc gtatagtgca gtcattgctt
    81121 gcttttctcc ttctgtttgg tatttttagg aattttctcc tcctgtagtg atagaaatcc
    81181 gtaggtcagg gttccaaaaa tgctgccgat aatcaggccg tacattagga aaggaacact
    81241 tttgtcgaat tgcatgagca acttcacaaa atctgaaagg gacatctgct gaacgaagac
    81301 tttatgaaag atgagtaagg taaagaggcc aatctgaaga ccgataaaca caatccaact
    81361 tcggaatttg atttgggctt tgctgtaggt tttgaggatg atttctgact tgtcatcttt
    81421 ttccatatgg agttctttga cgactctttg agtttttaag gtaatgaaaa aaatgagtcc
    81481 agagtaaacg tagggcatgg catagcgaac ggcctctatg aagcgtccaa ataatagata
    81541 aaacaagaag aggaagaagg aagaataaac gatttggacc atggaacggg cacaagcttt
    81601 gtagataatc tcttgtcggc attcatcaaa agggccttgg atatgaaaga gatttcggag
    81661 taggcgagtg gttaagtctt cttttttcat gttagtaacc tcctaaatga gcggttttac
    81721 tgattttctt ttacgaattg atagagataa taaagataaa tgatagaaga aaggctagcg
    81781 atagtcagca gtaaataata attccaattg cctgagacga gcatcagttg tggaaaagat
    81841 agaatcataa agtatagtgc taagttaagt gtgcgcgttt ttggggagtc aatctttaga
    81901 taagtcagta ctttgttaag ggctggaaca aagactagca cgaggaatat ctctctgatt
    81961 aagttccctg aaacgatgat gaagatgagc agagaactga acaaaagatg ataggtaagt
    82021 aaagttagta atgatttcat agggcacctc ttaatcctgg tcttttttag ctcttgcaat
    82081 acgaagtgag tcgacaatat gtatcatcac tccgaaaaag aaagctccca gtatagtttt
    82141 aaaaatatgt tttgtattta gaagagaact gataaaattt ggattttcac ttgttagggt
    82201 atcaatgagt ggaattataa acaatatcac tgttccataa atcgaacctg ctttcagacc
    82261 aggataacgt aactgtttct tttctttttt catgagtttc ctcctaatca ttatcctgat
    82321 ttttcctggc ttttgcaatg cgacgggaga tgagaatctg tataaccact ccaaagaaga
    82381 cagactggag gatacttgaa aaaatatttt taaaagcgag aagtgactga agatagtcct
    82441 gactctcacc tagcagtata tggagaagag gggttgtaaa aaaactcatt aatccataga
    82501 ctatcccagc tttcagacct gggtaatgta gttgcttact ttctttctca ttcagcatat
    82561 ctggttcaat agttgtaatc cctgtttttt gcatttggta ggtgagatat ccagcaacga
    82621 tgagggcaat cactaaaatt agaggaggat agactagagc cactagttga ggatatttat
    82681 aggccagaag gagtggaata agattgccga aaatcatcag ataaaagagg aagataaaga
    82741 cttgattgcc gatacgatca gcctcgcgtc gtttgtattc gtcaagtgga tcagaaatac
    82801 cgtatgtgcg cttgatcagt ttttcagtga aggtttcttt tttcatgagt tggctcctaa
    82861 tcctcatctt gatctttctt agtttttgca atgcgacggg agatgaggaa ctgtatgctc
    82921 gctccgaaga aaatagaacc gagaatgctt gatacaccat ttcttatagt gaggagagaa
    82981 tgaaaatagt cctgaccttc acctatgagt atactgagaa gaggagttat aaaaaacatc
    83041 catagaccaa agaacaaacc tgctttaaga cctgggtaat gtagttgctt actttctttc
    83101 tcactcagca tatctggatc aatagctgta atccctgttt ttttcatttg gtaggtgaca
    83161 tagccagcag cgatgagggc aatcactaaa atcagaggag gatagattag agccacttct
    83221 tgagggtatt tataggccag aaggagtgga ataagatttc cgaaaatcat cagataaaag
    83281 aggacgataa agacttggtt cccaatacga tcggcctcac gccgtttgta ttcgtcaagg
    83341 ggaccagaaa taccgtatgt gcgtttgatc agtttttcag tgaaggtttc ttttttcata
    83401 agtttgctcc ttttttaaaa atcttcctcc caaaagagac tgttgaggtc agtttggagg
    83461 ctgcgggcga gattgagaca gagttccagg gttggattgt acttgtcgtt ttcaatcata
    83521 ttgatggtct gtctcgagac accgatatcc ttggcgagct cgagctggga aatgcccagt
    83581 tccttgcgaa attctttcac acgattcatc tcttctcctt tctgatttgt gtcggatata
    83641 tttgactata ttatattctt ctatagagtg aatgtcaagc atatttgaca tatttcttaa
    83701 agaaatctta cttgggtttg ctctatttgt ctgactagtg caagctagtc ggatttgtgg
    83761 taaaatagat aagatatgac aaaagaattt catcatgtaa cggtcttact ccacgaaacg
    83821 attgatatgc tcgacgtaaa gcctgacggt atctacgttg atgcgacttt gggtggagcg
    83881 ggccatagcg aatatttatt aagcaaatta agtgaaaaag gccatctcta tgcctttgac
    83941 caggaccaga atgccattga caacgcacaa aaacgcttgg caccttacat tgagaagggg
    84001 atggtgactt ttatcaagga taacttccgt catttacagg cacgtttgcg cgaagctggt
    84061 gttcaggaaa ttgatggaat ttgttatgac ttgggagtgt ctagtcctca actagatcag
    84121 cgtgagcgtg gtttttctta taaaaaggat gcaccactgg acatgcggat gaatcaggat
    84181 gctagtctga cggcctatga agtggtgaat cactatgact atcatgactt ggttcgtatt
    84241 ttcttcaagt atggcgagga caaattctct aaacagattg cgcgtaagat tgaacaagca
    84301 cgtgaagtca agccaatcga gacaacgact gagttggcgg agattattaa gtcggctaag
    84361 cctgccaagg agctcaagaa gaagggccat cctgccaagc agatcttcca ggctattcga
    84421 attgaagtta atgatgaact gggagcggca gatgagtcca tccagcaggc tatggagatg
    84481 ttggctctag atggtagaat ctcagtgatt accttccatt cgctagaaga ccgcttgacc
    84541 aagcagttgt ttaaggaagc ttcaacagtt gaagttccaa aaggcttgcc cttcatccca
    84601 gatgatctca agcccaagat ggaattggta tcccgtaagc caatcttgcc aagtgcagaa
    84661 gaattagaag ccaataaccg ctcgcactca gctaagttgc gcgtggccag aaaaattcac
    84721 aagtaagagg aaaaatgatg gcagaaagaa tggaaaaaac aggtcaaata ctacagatgc
    84781 aacttaaacg gttttcgcgt gtggaaaaag ctttttactt ttccattgct gtaaccactc
    84841 ttattgtagc cattagtatt atttttatgc agaccaagct cttgcaagtg cagaatgatt
    84901 tgacaaaaat caatgcgcag atagaggaaa agaagaccga attggacgat gccaagcaag
    84961 aggtcaatga actattacgt gcagaacgtt tgaaagaaat tgccaattca cacgatttgc
    85021 aattaaacaa tgaaaatatt cgaatagcgg agtaagatat gaagtggaca aaaaaagtaa
    85081 tccgttatgc gacgaaaaat cggaaatcgc cggctgaaaa cagacgcaga gttggaaaaa
    85141 gtctgagttt attatctgtc tttgtttttg ccgttttttt agtcaatttt gcggtcatta
    85201 ttgggacggg cactcgcttt ggaacagatt tagcgaagga agctaagaag gttcatcaaa
    85261 ccacccgtac agttcctgcc aaacgtggga ctatttatga ccgaaatgga gtcccaattg
    85321 ctgaggatgc aacctcctat aatgtctatg cggttattga tgagaactat aagtcagcaa
    85381 cgggtaagat tctttacgta gaaaaaacac aatttaacaa ggttgcagag gtctttcata
    85441 agtatctgga catggaagaa tcctatgtaa gagagcaact ctcgcaacct aatctcaagc
    85501 aagtttcctt tggagcaaag ggcaatggga ttacctatgc caatatgatg tctatcaaaa
    85561 aagagttgga aactgcagag gtcaagggga ttgattttac aaccagtccc aatcgtagtt
    85621 acccaaacgg acaatttgct tctagtttta tcggactagc tcagctccat gaaaatgaag
    85681 atggcagcaa gagcttgctg ggaacctctg gaatggagag ttccttgaac agtattcttg
    85741 cagggacaga cggcattatt acctatgaaa aggatcgtct gggaaatatt gtccccggaa
    85801 cggaacaagt ttcccaacaa actgtagatg gcaaggatgt ttatacgact atttccagca
    85861 cccttcagtc cttcatggaa actcagatgg atgcctttct agaaaaagta aaaggtaagt
    85921 atatgaccgc gaccttggtc agtgcaaaga ccggtgaaat tctcgctacc acccaacgac
    85981 ctacctttaa tgcagatact aaagaaggaa tcactgagga ctttgtttgg cgtgatattc
    86041 tttatcaaag taactatgaa ccaggatcag ccatgaaggt tatgacgtta gcttcttcta
    86101 ttgataataa taccttccca agtggagaat acttcaatag cagtgaattc aaaatagcgg
    86161 atgcgacgac tcgagattgg gatgttaatg atggtttgac tactggtggg atgatgactt
    86221 tcttacaagg tttcgctcac tccagtaatg ttggaatgag tctacttgaa caaaaaatgg
    86281 gagatgctac ttggttggat tatctaaaac gctttaaatt tggggttcca actcgctttg
    86341 gcttgacaga tgaatacgct ggtcaacttc cagctgataa tattgttagt attgctcaaa
    86401 gctcatttgg gcaaggaatt tcagtgacac aaacacaaat gcttcgtgcc tttacagcta
    86461 ttgctaatga tggagttatg ctggagccaa aatttataag tgctatttat gatactaaca
    86521 atcagtctgt acgtaagtca caaaaagaaa tagtaggaaa tcctgtttcc aaagaggcag
    86581 caagcacaac tcgaaatcac atgatcttag ttgggacgga ccctctatat ggaactatgt
    86641 ataatcacta cacaggaaag ccaattataa cagttcctgg acaaaatgta gcagttaaat
    86701 ccggtacggc tcaaatcgct gatgagaaaa atggaggata cttggttggt tctaccaatt
    86761 atattttctc agttgtgact atgaatcctg ctgaaaatcc tgattttatc ttgtatgtaa
    86821 cggttcaaca gcctgagcat tattcaggta tccagttggg agaatttgcc accccaatct
    86881 tggagcgggc ttcagctatg aaagaatctc tcaatcttca atctccagcc aaaaatttag
    86941 ataaagttac gacagaatct tcttatgcaa tgcctagcat caaggatatt tcacctggtg
    87001 agttggcgga agccttacgc cgaaatattg tgcaaccaat cgttgtaggt actggaacaa
    87061 agattaaaga gacttctgta gaagaaggga ccaatcttgc accaaaccaa caagttctcc
    87121 ttttatcgga taaggtagaa gaaattccag acatgtatgg ctggaaaaaa gagactgccg
    87181 agacctttgc taaatggttg gatattgaac tggaatttga aggttcaggt tccgttgttc
    87241 agaagcaaga tgttcggact aatacagcta tcaaaaacat taaaaaaatt aaattaactt
    87301 taggagacta atatgtttat ttctattagt gctggaattg tgacattttt actaacttta
    87361 gtaggaattc cggcctttat ccaattttat agaaaggcgc aaattacagg ccagcagatg
    87421 catgaggatg tcaaacagca ccaggcaaaa gctggcacgc caactatggg gggacttgtt
    87481 ttcctcattg ctgcagttgt ggtgagtttc cttcttgctc ttttttcaaa acaattgacc
    87541 aataatgtgg gaatgatttt gttcatcttg gtactttatg gacttgtcgg atttttagat
    87601 gactttctca aggtctttcg taaaatcaat gaggggctga atcctaagca aaaattggct
    87661 cttcagctcc taggtggggt cgttttctac cttttctatg agcgcggtgg cgatatgctt
    87721 tctgtctttg gttaccaagt gcatctaggg attttctata ttgtcttcgc tcttttctgg
    87781 ctagtcggtt tttcaaacgc agtcaacttg acagacggta ttgacggtct agctagtatt
    87841 tccgttgtga ttagtttgtc agcttatgga gttattgcct atgtgcaagg tcagatggat
    87901 attcttctag tgattcttgc catgattggt ggcttgctcg gtttctttgt ctttaaccat
    87961 aagcctgcca aggtctttat gggagatgtg ggaagtttgg ctctcggtgg aatgctggca
    88021 gctatttcaa tggctctcca ccaagaatgg actctcttga ttatcggaat tgtttatgta
    88081 tttgaaacaa cttcggttat gatgcaagta agttatttca aaatgactgg tggtaaacgt
    88141 attttccgta tgacgcctgt acatcaccat tttgagcttg gaggattgtc tggtaaagga
    88201 aatccttgga gcgagtggaa ggttgacttc ttcttttggg gagttgggct tctagcaagt
    88261 ctactgaccc tagcaatttt atatttgatg taagaatggc accctgatgt tcagtttcag
    88321 ggtgtttttg cattctaaaa aacattggtc aattaaagtc aaaactcttg accttttctg
    88381 actaatgtag tatattataa acgtaaggta aatgaaagcc ttactcgaac gcttatactc
    88441 aatgaaaatc aacgagcaaa ttaggaagtg ctcaaaacac tgttttgagg ttacagatag
    88501 aactgacgtg gtttgaagag attttcgaag agtataaaaa cattggtcaa tcaaagtcaa
    88561 aatccttgac cttttctgac caatgtagta tattatgaac gtaaggtaaa tgaaagcctt
    88621 actcgaacac ttatactcaa tgaaaatcaa cgagcaaact aggaagctag acgcaggttg
    88681 ctcaaaacac tgttttgagg ttgcagatag agctgacgtg gtttgaagag attttcgaag
    88741 agtattattt aaagtaaaat agaaagaggt ggggtctatg tttaatctag aaatcttcag
    88801 aagtaaagat agtctactcc tgcttgaaaa agaaaaacca gaaatagtac ctagagtagc
    88861 gatttagcta atctaaattt tttaaaacaa aggtcaaaga tagtcaatat cagtaatcat
    88921 aactaagtaa ataaaaagag gtaaagaata tgaacaacaa ctttaataat tttaacaaca
    88981 tggatgattt atttaaccaa ttgatgggtg gtatgcgagg atacagttct gaaaatcgcc
    89041 gttacttgat taatggacgt gaagtaacac ctgaggaatt tgctcactat cgtgcaactg
    89101 gccaattggc aggaaatgca gaagttgatg gaaaaatgcc acaacagcct tcaggtatga
    89161 aacaagatgg tgtccttgca aaactaggtc gtaacttgac agcagaagcg cgtgagggca
    89221 agctggatcc tgttatcgga cgaaacaagg aaattcaaga agcatctgaa atcctctcac
    89281 gccgtaccaa gaacaatcct gttttggtcg gggatgcagg cgttggtaag acagcagttg
    89341 tcgaaggctt ggcacaagcc attgtgaacg gagatgttcc tgctgctatt aagaataagg
    89401 aaattatttc cattgacatc tcaggtcttg aggctggtac tcaataccgt ggtagctttg
    89461 aagaaaatgt gcaaaatcta gtaaacgaag taaaagaagt aggaaatatt atcctcttct
    89521 ttgatgaaat tcaccaaatt ctcggtgctg gatctactgg aggtgacagt ggttctaagg
    89581 ggcttgcgga tattctcaag ccagccctct ctcgtggaga attgacagtg attggagcaa
    89641 cgactcaaga cgaatatcgt aataccatct tgaaaaatgc agctcttgct cgtcgtttca
    89701 acgaagtcaa ggtcaatgct ccttcagcag aggatacttt taaaatcctt caaggaattc
    89761 gtgatctcta tcaacaacac cacaatgtca tcttgccaga cgaagttttg aaagcggcag
    89821 tggattattc tgttcagtat attcctcaac gtagcttgcc agataaggct attgaccttg
    89881 tcgatgtaac ggcagctcac ttggcggctc aacatcctgt aacagatgtg catgctgttg
    89941 aacgtgaaat tgaggcagaa aaagacaagc aagaaaaagc agttgaggcg gaagattttg
    90001 aagcagctct caactataaa acacgcatcg cagaattgga aaagaaaatc gaaaaccaca
    90061 cagaagatat gaaagtgact gcaagtgtca acgatgtggc tgaatctgta gaacgaatga
    90121 cgggtattcc agtgtcacaa atgggagcta cggacatcga acgtttgaaa gatatgggtc
    90181 atcgtttgca gacgaaagtt attggtcaag ataaggccgt tgaagcagta gcaaaagcta
    90241 tccgtcgtaa tcgtgctggt tttgatgaag gtaatcgccc aattggtagc ttcctctttg
    90301 taggaccaac tggggttggt aagacggagc ttgctaagca attggcgctt gatatgtttg
    90361 gaaccaagga tgcgattatc cgtttggata tgtctgaata cagtgaccgc acagccgttt
    90421 ctaagctaat cggtacaaca gctggttatg tgggttatga tgataatagc aataccttaa
    90481 cagaacgtgt tcgtcgcaat ccatactcta tcattctctt ggatgagatt gaaaaggctg
    90541 atcctcaagt gatcactctt ctcctccaag tcttggatga tggtcgtttg acagatggtc
    90601 aaggaaatac ggtgaacttc aagaacacag tcattatcgc gacctcaaat gctggatttg
    90661 gttatgaagc caacttgaca gaagatgcgg ataaaccaga attgatggac cgtttgaaac
    90721 cattcttccg tccagagttc ctcaaccgct ttaacgcagt tatcgagttc tcgcacttga
    90781 cgaaggaaga cctttctaag attgtggact tgatgttggc tgaagtcaac caaaccttag
    90841 ctaagaaaga gattgatttg gtagtcagtc aagcggctaa agactatatc acagaagaag
    90901 gttacgatga agtcatgggt gttcgtccgc tccgtcgcgt ggttgaacaa gaaattcgtg
    90961 ataaagtgac agacttccat ttggatcacc tagatgccaa acatctggaa gcagatatgg
    91021 aagatggcgt tttagtcatt cgtgaaaaag cctaatactc ttcgaaaatc aaattcaaac
    91081 cacgtcaacg tcgccttgcc gtactcaagt acagcctgcg gctagtttcc tagtttgctc
    91141 tttgattttc attgagtata agacaaaatt ttgagaataa aaaaagaagg agccagctga
    91201 aaaaaactgg ttcctttttt tatgtttaaa tcacatgacg ctcaaaagca tcatctgaaa
    91261 tcccttgttc caagatgagt tttgcccatt ctttagcaga aaagaggctg tggtccttgt
    91321 agttaccgca agattcgatg gttgttccag ggacgtcttc ccaagtagta gtttcagcga
    91381 tttccttgag cgaatccttg ataacagctg caatctcggc gctggtatga cgcccccaca
    91441 taatcatgtg gaaacctgta cggcaaccaa atggtgaaca gtcaatcatg ccgtcgatgc
    91501 gggtacggat gagtttggct aagaggtgct cgatagtgtg cagaccagcg gtagggattg
    91561 agtcttcatt gggttgtact aagcgaatgt cataattgga gatgatgtct ccttttggcc
    91621 ctgtttcttc cccaatcaag cggacatagg gtgctttaac aatagtgtgg tcaagttcaa
    91681 aactttcaac aataacttct tttgacatgg taaatccttt cagttttcta atttcattat
    91741 aacataaagc cggctcctga gacagagaga aaacctctcc gagggtggag aggttgaaat
    91801 cgttacttgc gatacaagcg gtcgtattgg tagtaagggt caaaggttac attgatacct
    91861 agtttgcgaa ggacattctt gtcttcatcg gttaagatga tggttgagtg ggcttcgctt
    91921 cctttgaggt taccaagctc ttccatagcg cgggcagcat caggattttc tgtagctgtg
    91981 atagcaagtg caatcaggat ttcatttgaa tgcaggcgtg gattgcggct acctagatga
    92041 tcgattttaa gaccttggat cggtttgaca agttcaggtt cgattagttt tacttcttta
    92101 gcaatgtcag ctgatttctt gatagcgttg ataagagcag ctgctgtagg gccgaagagt
    92161 tcggagttct tacctgtgac gatttctccg cttggtaatt caagggctag ggctggtccg
    92221 ccagtttctt ctgctttttg acgcgcaacg acagcaacct tgcggtctga aggtgtgata
    92281 ccgaggtcgt tcataagcaa ctcaattttc ttgacagcag attcgctaac tttttcggct
    92341 ttgaaatcaa gaacagtctg atagtagcga cggatgattt cttgtttaga ggcttcgata
    92401 gcagcctcat tatctgtaat agcgaaacca accatgttga cacccatgtc tgttggtgaa
    92461 gcgtatggag attcaccaag gatacgttct aacatgcgtt tgagaactgg gaaaatttca
    92521 atatcacggt tgtagttgac agtggtttct ccataggttt gaagatggaa agggtcaatc
    92581 atgttgacat catcaaggtc agctgtggca gcctcgtagg ccaaattgac tgggtgatga
    92641 aggggaagat tccaaactgg gaaggtttca aatttagcgt agccagactt gatgccattg
    92701 atttggtcgt ggtacatatt ggacatacag gttgccaatt ttccagaacc aggtccagga
    92761 gcggttacga caatcaagtt gcgactggtt ttaatgtagt catttttccc cataccttct
    92821 ggtgaaatga tgtgatccat atctgtcgga tatcctttga ttggataatg aagataagaa
    92881 tcaattccgt ttttttcaag ttgatttcgg aaggcatctg cagctggttg gccagcgtac
    92941 tgtgtgatga caacggaacc aacaaaaatc cctaattcat taaatttgtc aatcaaacga
    93001 agaacttctt ggtcataaga aatgcccaag tcaccacgtg ctttggaatg ctcgatatta
    93061 cttgcattaa tagcaatcac aacctcaacc tgctctttca attcttgcaa gagcttgatt
    93121 ttgttgtcag gctcataacc aggaaggaca cgagcagcat ggaaatcttc taacatttta
    93181 ccaccaaact ccaagtagag cttgccgtca aattgattaa tgcgctccaa gatgtggtcg
    93241 cgttgtagat tcaaatattg ttcagaacta aaagcttgtt ttttcatttt tttacctctg
    93301 acctctatta taataaaaaa ttggaagtta ggaaactatg gagtcaaaaa agaaattaaa
    93361 aagattaggc aaacgcttgc acaaaattct aaaaagcgct atcatagact atagattatt
    93421 aaaataatga ggtaagaaga tgcaagaaaa atggtggcac aatgccgtag tctatcaagt
    93481 ttatcctaag agctttatgg atagcaacgg agatggaatt ggtgatttgc caggtattac
    93541 cagtaagtta gactatctag ctaagttagg aatcacagcg atttggcttt ctcccgttta
    93601 tgacagccct atggatgata atggctacga tattgctgat tatcaagcaa ttgcagctat
    93661 tttcggaacc atggaggata tggaccaact gatcgcagaa gccaagaagc gtgatattcg
    93721 tatcatcatg gacttggtgg tcaatcatac ctcagatgaa catgcttggt ttgtcgaggc
    93781 ctgtgaaaat cctgatagtc ctgagagaga ctactatatt tggcgggatg aacccaatga
    93841 tttggattct atctttagtg gttctgcttg ggaatacgat gaaaagtcag gtcaatatta
    93901 tctccacttt ttcagtaaga aacagcccga tctcaactgg gaaaatgaaa aacttcgtca
    93961 gaaaatttat gagatgatga acttctggat tgataaaggc attggtggtt tccgcatgga
    94021 tgtcattgac atgattggca aaattcctga cgagaaagta gtcaataatg gtcctatgct
    94081 ccatccctat ctcaaggaga tgaatcaggc gacctttgga gataagaatc tcttgacagt
    94141 aggggagact tggggagcaa cgccagcgat tgccaagctc tactcagatc caaaggggca
    94201 agaattgtct atggtcttcc agttcgaaca catcggtctt cagtatcagg aagggcaacc
    94261 taaatggcac tatcaaaaag agctgaatat cgctaagtta aaagaaatct tcaacaaatg
    94321 gcagacagag ttaggagttg aggacggttg gaattccctc ttctggaaca accatgacct
    94381 tcctcgcatc gtctcaatct ggggaaatga ccaagaatac cgcgaaaaat ctgccaaagc
    94441 ctttgcaatc ttgcttcatc tcatgagagg gactccttat atctaccaag gtgaggagat
    94501 tgggatgacc aactatccct ttgaaacact ggaccaagta gaagatattg aatctcttaa
    94561 ctatgcgcgt gaagctcttg aaaaaggtgt ttcgatggaa gaaatcatgg acagtatccg
    94621 tgtcattggt cgtgacaatg cccgtacccc tatgcaatgg gacgagagca aaaacgccgg
    94681 tttctcgaca ggtcagcctt ggttggcagt caatccaaac tacgaagaaa tcaatgttca
    94741 agaagcactg gcaaatccag attctatttt ctatacttat aaaaaactcg ttcaaatccg
    94801 caaggagaat agctggctga ttcgagctga ctttgaattg cttgatacgg ctgacaaggt
    94861 ctttgcttat atccgtaaag atggcgaccg tcgttttcta gttgtggcca acttgtccaa
    94921 tgaagagcaa gacttaacag tagaaggaac agtcaaatct gtcttgattg aaaacaccac
    94981 ggctcaagaa gtctttgaaa aacaaatctt agctccatgg gatgctttct gtgtggaatt
    95041 gactgactaa aatgagagag agtgggcaaa aactcgactt caggagaaaa tgaagtaaat
    95101 ctttccacaa taaaatgcat agtaccaagt tttttcaaga cctgatatta tgcgtttttt
    95161 gttttaaaga cttttttccc agcctctttt tgctaaaagt tgtgtaaaaa ctcttttaaa
    95221 aacatttgtt agaattttct aacaaattcc ataagaactc ttgcatttat aaaaaaatag
    95281 ggtataatag tgaaaatact attttgaagg agattattta tgcaatcgaa aaagtggctc
    95341 ataggagcag gagtgacctt gagtacagcc attcttttaa cagcttgtgg gaaaagtgaa
    95401 aagaatgcag atgctcccaa aacattttct tatgtttatg cagttgatcc atcatccttg
    95461 gattatagcc ttacaagtaa aagttcaact tctgacgtaa taggtaatgt cgtcgacggt
    95521 cttttagaga atgataaata tgggaatctc attccttctc tagcagagga ttggtcagtt
    95581 tctaaagatg gtttgactta tacctacaaa ctacgtaaag gtgtgaagtg gtatacttca
    95641 gaaggagaag agtatgcgga agttaaagct caggattttg ttacaggtct gaaacatgca
    95701 gcagatggaa agtctgatgg tctttctttg gttgagaaat ctatcaaagg attggaggct
    95761 tatgttagtg gtgagacaaa cgacttctca actgtaggtg tgaaggctct tgatgattat
    95821 acggtagaat atacccttaa taacccggaa agtttttgga actctaaagt aaccacagca
    95881 accatgcttc ctgtaaatga agaatttttg aatgcaacag gcaaggatta cggagcgcca
    95941 actccatcaa gtattcttta caatggccca tattttttga aatctttgat ttctaaatct
    96001 gtgattgaat atgaaaaaaa tcctaactat tgggataagg acaatgtcaa aattgataat
    96061 gttaaattga cattctatga tggttcagat caagaatcct taattcgtag ctttacacaa
    96121 ggtgcctata ccactgcacg tctttttcca gcaagctcaa actttgagtc aactaagaaa
    96181 gagtacggag ataagattgt ctatagtcca caagaggcaa caagctacta cctcactgtg
    96241 aatgtaaacc gccagtctta caataaaaca gctaaaacag atgagtcaca aaaaacatca
    96301 acaaaagaag ctcttctcaa taagaacttc cgtcaggctc ttaattttgc atttaatcgc
    96361 cacgcctata cagctcaatt aaacggtgaa gagggtgcgg ataagattat tcgtaatagt
    96421 ctagtgccag ataattacgt tcaagtagct gggaagacct tcggacagtt ggctcaggat
    96481 gaactactga aatatggaga acagtggaaa gatgtgactc tcacagatgg taaggataca
    96541 atttacaatc caacaaaggc caagtctgca tttgaaaaag cgaagtcaga attgcaagct
    96601 aagggagtga gtttcccgat tcatctggat gtgcctgttg agcaaactga tgtagttgcg
    96661 gttcaacaaa ccaattcgct aaaacaatca attgaagaaa cgcttggaac ggagaatgtc
    96721 attatagatg ttcttcaaat gacagataat gagaaggaaa gtattacttc tcaagctaaa
    96781 gttccaaccc aaaaagatta tgatttgaac ggaacaggtt ggggaccaga ttaccaagat
    96841 ccagcaacct atctcaatat tttagatgct aagaagggtt ctgccttgaa acatctaggt
    96901 ataacaaagg gcaaggatcc tgaagttgtg gcgaaagttg gcttggatga atacaagaag
    96961 ctcttggatg atgcggcttc tgagacaagt aatcttgata aacgatacga aaagtatgcc
    97021 aaagcacagg cttgggttac tgatagttca cttcttattc cagttgcttc ttcagggggc
    97081 tctcctatgg ttagtcgtac tgttccattt accaaagctt attcacaggt cggtattaag
    97141 ggggatccat ttatttttaa aggaatggaa cttcaaaatg atattgtgac aactaaagag
    97201 tatgatgcgg ccttcaaaaa gtggcaaaag gaaaaactgg aatcgaatgc tcagtatcaa
    97261 aaggatttag aaaagcacat aaaataatga gaatgagaat cttgctttcg ttaggttatc
    97321 agttaattca ttgatattca aatgataaat cgtataaaaa caagggagga ttgtatgaaa
    97381 agcagaaatc ctttgttttt ttataaccaa agtttataaa ctttggttat aaaaattcaa
    97441 ttaactttac aaattcccac tattttggta aaataaatat atgttataaa aactaacata
    97501 aaggagaaag aagatgacta caaaaaagcg tatccttagt gcaggactga cttttgcagc
    97561 tgctttgctt ttagctgctt gcggacaatc aggttcagat acaaaaactt actcatcaac
    97621 ctttagtgga aatccaacta catttaacta tctattagac tactacgctg ataatacagc
    97681 catcattacc aacctagttg atggtttgct tgaaaatgac aaccacggaa acctagttcc
    97741 atctttggca gaagactggt ctgtttcaag cgacggtctg acttatacct acaaattgag
    97801 aaaagatgcc aaatggttca cagctgacgg tgaagagtac gccccagtca aggctcagga
    97861 ttttgtgaca ggtatcaagt atgcagtgga taataaatca caggccattg acttgattca
    97921 aaactcgatc aagggcttga atgattatat tacaggagcg gattctgact tttctaaggt
    97981 tggggtgaag gccattgacg accagactgt cgagtatact ttgacacgcc cagaacctta
    98041 ctggaattca aaaacaacca atagtattct tttcccagta aacgaagagt ttttaaactc
    98101 aaaagggaaa gattttggga ccctatctcc agatagcatt ctctacagcg gaccttattt
    98161 gttaaaagat ttcacatcaa aatcatcaat cgagtatgtg aaaaatccgc attactatga
    98221 tcatgacaaa gtatcaattg aacatgtgaa attggcttat tttgatggct cagaccaaga
    98281 attgaccatc cgtaactttg aaagtggagc ttattcaatc gctggggttt atccaaatag
    98341 ttcaaacttt gctaagacta aggaaaaata taaggataat atcgtctata gcttgcagga
    98401 caagacttct tggtacttca attttaacgt caaccgtaag gcatacaacc atacatctaa
    98461 aacgacagat gagcagaaga agtcaactga gacagctgtc ttgaacaaga acttccgcca
    98521 agcagtgaac tttgccttgg accgcacagc ctattctgcc cagtcaaatg gagaagaggc
    98581 ggctagcaag acccttcgga acaccttggt gcctcctaca tttgtccaag ttggagacaa
    98641 gacctttgga gaagtagtcg cttctaaatt ggtcaactat ggcacagaat ggtcaggtat
    98701 taacttggca gatgctcagg atgcctattt caacaaagaa aaagcccaag caaaatttgt
    98761 ggaagctaaa aaagaattgg caagtcaagg tgtgactttc cctattcact tggatgtggc
    98821 ggttgatcag acaagtaaaa atgccgtgac aggtatgaac tcagttaagc agacccttga
    98881 gtcagtttta ggtgctgata acgttgtcat tgatgttcag caactttcaa cagatgattt
    98941 taataatgta gccttcttag cgccaacagc agctgatcgt gactatgatt tgaactttga
    99001 tggctgggta ggtgactacc aagatccatc aacttatctc aatcctttca atgcagagga
    99061 tggcttctac cttaagattt ttggactaga tgccaaggaa gacaaggaaa aaatcactag
    99121 tctaggtctg gatacctaca ctaagatgct caaagatgca gatagtgaaa acaaagatgt
    99181 agctaaacgt tacgaaaaat atgctgaagc acaggcttgg atgattgaca attctctgat
    99241 tatgtcagct atgtcaagtg gtggaacagc atctgtaacc aaagtaacgc catttacaag
    99301 aggctattcg ttggttggta tcaagggtga tggcaataac tacaagtaca tgaaactgca
    99361 aaaagacact gttacaacta aacagtttga agaagctaag accaaatggg agcaagaaag
    99421 caaaaaagca atcgaaaaag cccaaaaaga agcagaaaaa catgttaaat agttagaaat
    99481 agccttttca agcaaaatcc taaagacaaa catcagtttt ggtgcttgtc tttttaaatc
    99541 actcggctat tgaaaactga gaaatgattt gttttgtgct aaaatagatt gaaacgaata
    99601 ctcaataaaa atcaaagagt aactgggaag ttagctcaaa gtacagcttt gaggtggtag
    99661 atagaactga cgaagtcagt tcaaaatact gttttgaggt tgcagatgga cgctgacgtg
    99721 ctttgaagag attttcgaag agtataaaga tcctctcttt tgctatagtt aaggagatga
    99781 gaggtaaatg ataaggaaga gactatgtac gactatctaa tcgttggtgc tggtttgtcg
    99841 ggagcaattt ttgcttatga agcaaccaag cgtggaaaaa aagtaaaagt tattgataaa
    99901 cgtgaccaca ttggtggaaa tatctactgt gagaatgtag aaggggttaa tgttcataaa
    99961 tatggtgccc atatctttca tacttctaat aaaaaagttt gggattatgt taatcaattt
   100021 gctgaattta acaactacat caactcgcct gtagctaatt acaagggtag cctttataat
   100081 ctacctttca atatgaatac tttctatgct atgtgggaga caaaaactcc tcaagaagtg
   100141 aaagataaga ttgctgagca aacggctcac atgaaggacg ttgaacctaa aaatttggaa
   100201 gaacaggcta tcaagttgat cggtccagat atttatgaaa aattgattaa aggatatact
   100261 gaaaagcaat ggggacgttc tgcgactgac cttccaccct ttatcatcaa acgtctacca
   100321 gttcgtttga cttttgataa taactacttc aatgaccgtt accagggtat tccaattggc
   100381 ggttacaacg tcatcatcga aaatatgctc aaggatgtgg aagtagaact tggtcttgac
   100441 ttttttgcca atcgtcagga attagaagct tctgctgaaa aggttgtctt tacagggatg
   100501 attgaccaat acttcgatta taaacatggt gagttagaat atcgtagtct tcgttttgag
   100561 catgaagttc tcaatgaaga aaactatcaa ggaaacgcag ttgtcaacta tacagaacga
   100621 gaaattcctt atactcgcat tattgagcat aaacactttg agtatggtac acaagctaaa
   100681 acggtcatta ctcgtgaata cccagctgat tggaaacgag gagatgaacc ttattatcca
   100741 atcaatgatg agagaaacaa tgctattttt gccaaatatc aggaagaagc ggcaacaaat
   100801 gacaaggtta ttttctgtgg tcgtttagca gattataaat actatgacat gcatgtggtc
   100861 attgaacggg ctttggaagt agtcgcggaa gagttgggac aataatgcaa ggattctgtc
   100921 attttagaat ctttgctact taagattttt agaagtaagg tcaacaagat tcttttctgc
   100981 ttatcagaag agaacttctg ttggcttttt tttggcataa atgaacaatt ttatttttca
   101041 gaatatatca aatataacaa ataactctta aaattcagaa aattctattg acaggacttg
   101101 aaaaagagtc tataatgaat aaaaaaacaa aggagaagac tatgaaaaca agaaaagtat
   101161 tggctcttgc gggagtaacc ttattagcag ctggtgtttt agctgcttgt tctgggggtt
   101221 caggtgctca aggtgaaaaa acctttgcct ttacctacga gacacatcca gataatctca
   101281 actatttgac aactggtaag gcagcaactt ctgagattac tagtaatgtg atcgatggat
   101341 tacttgaaaa tgataaatac gggaacctta ttccctcaat ggcagaagac tggtcggtct
   101401 ctaaggatgg cttgacttat acttataaga ttcgtcagga tgccaagtgg tatacatctg
   101461 agggagaaga gtacgctcct gttaaggctc aggactttgt aacaggactt aaatatgcaa
   101521 cagataagaa agcagaagcc ctttacttgg tacaggattc aatcaaaggt ctggatgcct
   101581 atgccaaagg tgaaatcaca gactttgctc aagtcgggat taaagccctt gacgatcaga
   101641 cagtccaata caccttgaac aaacctgaaa ctttttggaa ttctaaaaca accatgggtg
   101701 tgcttgcgcc agtcaatgaa gagtttttga attcaaaagg ggatgatttt gccaaagcta
   101761 cggatccaag tagtctcttg tataacggcc cttatttgtt gaaatccatt gtaactaaat
   101821 cctctgttga atttgcgaaa aatccgaact actgggataa agacaatgtg catattgaca
   101881 aggtcaaatt gtcattctgg gatgggcaag ataccagcaa accagcagaa aactttaaag
   101941 atggtagcct tacagcagct cgtctttatc caacaagtgc aagtttcgca gagcttgaga
   102001 agagtatgaa agacaatatc gtctatactc aacaagactc tacgacttat ttagtaggaa
   102061 caaatattga ccgtcaatct tataaacaca catctaagac tagcgacgaa caaaagacat
   102121 ctactaaaaa agctctctta aacaaggatt tccgtcaggc tattgccttt ggttttgacc
   102181 gtacagctta tgcttctcag ttgaatggag aaactggagc aagcaaaatc ttgcgtaatc
   102241 tctttgtgcc accaacattt gttcaagcag atgggaagaa ctttggcgat atagtcaaag
   102301 aaaaattagt gacttatggg gatgaatgga aggatgtcaa tcttgcagat tcacaagatg
   102361 gtctttacaa tccagaaaaa gctaaagcag aatttgccaa agccaaatca gccctacaag
   102421 ctgagggagt acaattccca attcacctag atatgcctgt tgaccagaca gcaactacaa
   102481 aagttcaacg tgtccaatct atgaaacaat ccttggaagc aactttagga actgataatg
   102541 tcgttattga tatccaacaa ttgcaaaaag atgaattgct taatgtaact ctatttgccg
   102601 aaaatgctgc tggcgaagac tgggatttat cagataatgt cggttggggt ccagactttg
   102661 ccgatccatc aacctacctt gatattatca aaccttctgt aggagaaagt actaaaacat
   102721 atttaggatt tgactcaggg gaagataatg tagctgctaa aaaagtaggt ctatatgact
   102781 acgaaaaatt ggttactgaa gctggtgatg agactacaga tgttgctaaa cgatatgata
   102841 aatacgcagc agcccaagct tggttgacag atagtgcctt gatcatccca acaacttcta
   102901 aaactggtcg tccaatcttg tctaagatgg taccatttac aataccattt gcattgtcag
   102961 gaaataaagg tacaagtgac ccagtcttgt ataaatacct tgaacttcaa gacaaggcag
   103021 ttactgcaga tgaatatcaa aaagctcaag aaaaatggat gaaagaaaaa gcagaatcca
   103081 ataaaaaagc gcaagaagaa ctcgcaaaac atgtgaaata agataaaaag agactgagca
   103141 aaaagtcttt aaaagcaaaa cgcatattgt caggtgatga aagccttgat cgtatgcgtt
   103201 ttattgtggg gaaatgtact tgatctctgt atttcatttt gaaaatgaca aaatcctgag
   103261 tttagagttc tcaggatttt ttcgtttact gttgtggttg ctgttgaact tgtggatttt
   103321 gtggcgttgg ttgtactggt tgtgtcggtt gaacagcttg tccttgatta ggatcagttg
   103381 ctggagcatt attgggttgt tgaccaaccg tagtacttgc ctgtgtagtt gaactttcag
   103441 ctgttgagga ttgttgagta gagggttcag tccatattgg gcgagctcca tttttgaata
   103501 caaattcccc gtttctgaaa agtccgtctg gcatcgtcca gtcttctgga tgagtatctt
   103561 ctgatagata cgttatcatt gagcgataaa ctttagctgc aactaggaaa ccatctccaa
   103621 cgataggagt taaacgattc gaataacctg tccatacagc catagaatac ttacgagtat
   103681 aaccaacaaa catttcatct ggagctacat agccagtgtt cttgatgtgt ttttcaattt
   103741 catcatctgt gtagttagaa gtacctgtct taccagcttg cgctaaccat gggagatagg
   103801 ctccacgacc agttccgtat gccaagacag ttttcatcat ttcggtcatc atgtaagcag
   103861 ttgtttcttt catagctcgt gtacctacat ctgaaaattc tttttcacta ccgtcactga
   103921 agacgacctt attgatatac atgggtttgt ggtaaattcc accgttggca aaggcagcat
   103981 aagcagcagc cattttttca ctacttgctc cgtattgttt attagattct gttgtattac
   104041 ttgaaatggc gtttgcataa tgcatgcttg gatagtcgat accaagacca ttaaggaagg
   104101 ttttagctct atctagaccg accttattca aagtctcaac ggctgtgaca tttcgtgatt
   104161 gttgaagagc atattgcaga gtaatattac cgaaatatgc tctatcccag ttgtagacag
   104221 gtgtgcttgt tcccggatag ttataaggaa tatcattaac catagttgca gtggaatcat
   104281 aaacaccgta ttctatggca ggtgcataat cggtgattgg tttcatagca gaaccccagt
   104341 cacgattggt ttccacagct tggttggtac caaatgaaac gttacttgct tggtgacgag
   104401 ctccaagttg ggcgatgact ttaccatttg aaacatctac gaccgtagat gcgacttgca
   104461 aatcatcgtc agggtaagag acgtattgat cggagttgta gatatcccac agatgttttt
   104521 gagcttcttg gtctacattt gtgtaaacat ccatcccagt agttagaagg ttatagccag
   104581 tttcttgttc tacttgattg atgacctcct tgaggtaatt atccatgtaa gcagggtaat
   104641 tacttgctga tttgagactt tgtagtccat cagtaattgg tgtattgact gctttctcat
   104701 actgttcagc agagatgtaa ccttgatttt tcatttcaga taagaccaag tttcggcggt
   104761 cttgggctgc ttctggatgt gaataggggt catattggtt tggtgcctga ggcattccag
   104821 ccagcaaggc taactgaggt aaacttaaat tattgaggtc tttaccatag tagttttgag
   104881 ctgctgtctg cattccatag ttgccattag acatgtagac cttatttata tagtaggtca
   104941 agatttcctg tttggttgct ttttgttcta actgaatcgc taaccaagct tcctgagcct
   105001 tacgagaaat agtctggtcg gaagtcgagg ttgaaaagta agtcaactta atcaactgtt
   105061 gggtgagagt tgatccacct tggagggaat tactttgcag attgcgcaag aaagctccca
   105121 ggatacggat ggaatcaatc cccctgtggt cgaagaagcg atggtcttcg atagaaacga
   105181 ttgccttaac caaatctgtg ggaatatcat tagcttgggc attgacgcgg cgttcagaac
   105241 ccaagtcagc aatgagttga tttttattgt cgtagatttt actagaagtt gttgcaacta
   105301 gtttactctc ggataggcta ggagccttgc taacgtagta gaaaaaaact cctccgccta
   105361 agacaatggc tgcgataacc aagcttaaga agctaatgct cagatacttg attaggcgca
   105421 gaatcgttgg tttgttcatc ttgttttacc acctaataaa tgttctttga taacattgag
   105481 ataaggaatt tgagggaagg caccagcctt gatttcatat ccatattctc gaatatatcc
   105541 aagtggcatt gatttttgtc ccttatcttg atgatagaag cgaatcaaat cgaatgccgg
   105601 caataagtag gtttcttgct gagaagaaaa gtgaagaagg acaaagcaga ttccttgttg
   105661 ggcaaggact tgttccatat gctgaatctg atgtggatga aaatttttca tcggaatcgc
   105721 acgtttttgt tttgtttcct tggcttcaaa gtcgatgtaa tatccattat aaacgccaga
   105781 atagtccgtc gttgaagctt gtcgaaaata ggcctcaaca atcttggcac gacttcgttg
   105841 tggatagtcc actcgtacga tttgaatagg agttggtttc ttgtgtataa cagccaagcc
   105901 ctgagacaaa tagtagtcgt tggtagcatt gatcatcttt tcaaaagaca ttcctcgatt
   105961 tgcgaaattt ttgggttgag aaagagaggt ttgtcttttt tgtgatgaaa gtttatgtgg
   106021 atagttgacc ataattctcc ttattggtac aataacatca ctctattata ccataaattt
   106081 gcacagaaag ggttaaaaat ggctacagct ttggttttag gctattctgc ttttgatttg
   106141 ggtttatttt ctgacaagga tcctcgtctt aaattgataa aaaaagcaat acgtaaagat
   106201 ttagaggcta tggcagcaga tggggtgtct tggcttgtgt ttacaggaag tttgggtttt
   106261 gaatattggg ttttagaggt tgctcaggaa atgaagaccg aatacggttt ccagttggcg
   106321 accatttttg cttttgaaac ccatggggaa aattggaatg aaggcaatca gatgaaactg
   106381 agtcgtttta agcaggtaga ctttgtcaaa tatgcttatc ctcgctatga acacaagggg
   106441 cagttaagag attaccagca gtttttgctg gaaaatacga ctagttccta tcttttttat
   106501 gatgaagaaa atgagacgaa actagcttat ttttaccaaa agatgaaaaa tcaagaggac
   106561 tattttataa agagattaac atttgatcaa ttaaatgaac ttgctgaaaa tttttccgaa
   106621 aattgaagct ttgaccttga tttttgtttg ccttttttta tataataata ctagcaagcg
   106681 agaatggaga gagacatggc aagtattatt ttttcagcga aagatatttt tgaacaagag
   106741 tttgggcgtg aagtccgtgg gtatagcaag gtagaagttg atgagttttt agacgatgtc
   106801 atcaaggact atgaaaccta tgctgccttg gtcaagtcac ttcgtcagga gattgcggat
   106861 ttgaaggaag aattaactcg taaaccgcaa gtgagttcgg ctccaagtcc tagtcaccca
   106921 gatccaattg atgtggctgc ttcatcttct atgacgaatt ttgatatttt gaaacgcttg
   106981 aatcgtcttg aaaaagaagt attcggtaaa caaattttag acaatactga tttgtaattc
   107041 aggtcttgtt acatgcaatt tttggataat cgcgtgagga gagttgcttc tcatgaggaa
   107101 agtccatgct agcacaggct gagatgcctg tagtgtttgt gctaggcgaa accataagcc
   107161 tagggacgag aaatcgttac ggcagttgaa atggctaagt ccttggatag gccagagtag
   107221 gcttgaaagt gccacagtga cggagtcttt ctggaaacag ggagagtgga acgcggtaaa
   107281 cccctcaagc tagcaaccca aattttggtc ggggcatgga gtacgcggaa acgaacgtag
   107341 tattctgact gctatcagct agagctgtta gtggtagaca gatgattatc gaaggaagtg
   107401 gtcctagtca cttctggaac aaaacatggc ttatagaaaa ttgcatatag gttggggctg
   107461 agaaattttc tcaacctcat tttttaaagt ggacatatag aaaggtcttg caagactgta
   107521 acatgaaaaa agaatttaat ttaattgcaa ctgtggcagc agggcttgaa gctgttgtag
   107581 gacgagaagt acgagagctg ggctacgatt gtcaggttga aaatggacgt gttcgttttc
   107641 aaggagacgt gagagctatt atcgaaacca acctctggct tcgggcagca gatcgtatca
   107701 aaattatcgt aggaactttc ccagctaaga cttttgaaga gctgtttcag ggagttttcg
   107761 ctttagattg ggaaaattat ttaccactcg gagctaggtt cccaatttcg aaagcaaaat
   107821 gtgttaaatc taaactgcat aatgaaccca gtgttcaggc tatttctaag aaagctgttg
   107881 tcaagaaatt gcagaaacac tatgctcgcc cagaaggtgt tcctctgatg gagaatggtc
   107941 cagagtttaa gattgaggtc tctattctca aagatgtggc aactgtcatg attgatacga
   108001 caggctccag tctctttaag cgtggctatc gtaccgaaaa aggcggcgct cctatcaagg
   108061 aaaacatggc ggcagctatt ttacaacttt ctaactggta tccagacaag cctttgattg
   108121 atccgacctg tggttcgggg actttctgta tcgaggctgt catgattgct cgaaagatgg
   108181 caccaggact tcgtcgctct tttgcttttg aagaatggaa ctgggtcagc gatcgcttga
   108241 ttcaagaagt gcgtacagaa gcagctaaaa aagtggatcg tgagctggag ctggatatca
   108301 tgggctgtga tatcgatgca cgcatggtgg aaattgctaa ggccaatgcc caggcagttg
   108361 gtgttgcagg agacattact tttaagcaga tgcgcgtgca ggatttgcgt tccgataaaa
   108421 tcaatggtgt gattatttcc aatccgcctt acggggagcg tttatcagat gatgcagggg
   108481 tgaccaagct ctatgctgag atgggtcaag tatttgcacc actgaaaact tggagtaagt
   108541 ttatcctaac tagtgatgaa gcatttgaaa gtaagtatgg tagtcaggcg gataagaaac
   108601 gtaagttata caacggaacc ttgaaagtgg atctgtatca atattttggt cagcgtgtta
   108661 aacgccaaga ggtaaaatag aaagggatac tcatgagtaa gaaaagacgg aatcgtcata
   108721 aaaaagaaaa ccaagaatcg cgatttgatt ttgatgaagc aaaagagtta acagttggtc
   108781 aagctattcg taaaaatgaa gaagtggaag caggagtctt gcctgaagat tccattttgg
   108841 acaagtatgt caagcaacac aaagatgaaa tcgaagcaga taagtttgcg actcgccaat
   108901 acaaaaagga ggagttagtc gaaactcaga gtctggatga tttaattcaa gagatgcgtg
   108961 aggctgtaga agagtcagaa gcttcttcgg aggaagttcc atcttctgaa gacatcttac
   109021 cacccttgcc tctggacgat gaggagcaag gcttggattc tctattgcta gaggatgaaa
   109081 atccaacaga aatgactgaa gaagtggaag aggagcaaaa cctttctcgt ctggatcaag
   109141 aggactcaga aaagaaaagt aaaaaaggct ttgttttgac cgctttggcg cttgtatcag
   109201 tgattatctg tgtcagtgct tactatgttt accgtcaagt gaatcgctcg accaaggaaa
   109261 ttcaaacttc tcaatcagct acagccaatc aatcagatgt ggatgatttt aatacacttt
   109321 atgacgcctt ctacacagat agcaataaaa cggctttgaa aaatagccag tttgataaac
   109381 tgagtcaact caagacctta cttgataagc tggaaggtag tcgtgaacat acgcttgcca
   109441 aatcgaagta tgatagtcta gcaacgcaaa tcaaggctat tcaagatgtc aatgctcaat
   109501 ttgaaaaacc agctattgtt gatggtgtgt tggacactaa cgctaaagct aaatcggatg
   109561 ctaaatttac agatattaaa actggcaata cggagcttga taaagtgcta gataaggcta
   109621 tcagccttgg taagagccag caaacaagta cttctagctc aagttcaagt gaaactagta
   109681 gctcaagctc aagtcaagcc agctcaaata cgactagtga gacaagccca agtagttcaa
   109741 atgctgcctc aaatgagact agaagttctc gtagcgaagt caatatgggc gtatcaagtg
   109801 caggggttgc tgttcaaaga agtgctagtc gtgttgccta taatcagtct gctattgatg
   109861 atagtaacaa ctctgcttgg gattttgcgg atggtgtctt ggaacaaatt ctagcgactt
   109921 cacgttcacg tggctatatc actggagacc aatatatcct tgaacgtgtc aatatcgtta
   109981 atggcaatgg ttattacaac ctctacaagc cagatggaac ctatctcttt acccttaact
   110041 gtaagacagg ctactttgtc ggaaatggcg ctggtcatgc ggatgacttg gactactaag
   110101 cagtcgttac aaaattcttt cttttcaaaa gtaaaaatga taaaataaaa caaatcaaac
   110161 aagaggagtg tcaaatgaca aaagctaact ttggtgtcgt aggtatggcc gtaatgggtc
   110221 gtaaccttgc ccttaatatt gaatctcgtg gttacacagt tgctatttac aaccgtagta
   110281 aagaaaaaac ggaagatgta attgcttgcc atcctgaaaa gaactttgta ccaagctatg
   110341 atgttgaaag ttttgtaaac tcaatcgaaa aacctcgccg tatcatgctc atggttcaag
   110401 ctggacctgg tacagatgct acaattcaag cccttcttcc acaccttgac aagggtgata
   110461 tcttgatcga cggaggaaac actttctaca aagatacaat ccgtcgtaat gaagaattgg
   110521 caaactcagg catcaacttt atcggtactg gggtttctgg tggtgaaaaa ggtgcccttg
   110581 aaggtccttc tatcatgcct ggtggacaaa aagaagccta cgaattggtt gcggatgttc
   110641 ttgaagaaat ctcagctaaa gcaccagaag atggcaaacc atgtgtgact tacatcggtc
   110701 ctgatggagc tggtcactat gtgaaaatgg ttcacaacgg tatcgagtat ggtgatatgc
   110761 aattgatcgc agaaagctat gacttgatgc aacacttgtt aggtctttca gcagaagata
   110821 tggctgaaat ctttactgag tggaacaagg gtgaattgga cagctacttg attgaaatca
   110881 cagctgatat cttgaaccgt aaagacgatg aaggccaaga tggaccaatc gtagactaca
   110941 tccttgatgc tgcaggtaac aagggaactg gtaaatggac tagtcaatca tcacttgacc
   111001 ttggtgtgcc attgtcactc atcactgagt cagtatttgc acgttacatt tcaacttaca
   111061 aagaagaacg tgtacatgct agcaaggttc ttccaaaacc agctgacttc aaatttgaag
   111121 gagacaaggc tgagttgatt gaaaagatcc gtcaagccct ttacttctca aaaatcattt
   111181 catatgcaca aggttttgct caattgcgtg tagcttctaa agaaaacaac tggaacttgc
   111241 catttgcgga catcgcatct atctggcgtg atggctgtat catccgttct cgtttcttgc
   111301 aaaagattac agatgcttac aaccgtgatg cagaccttgc caaccttctt ttggatgagt
   111361 acttcttgga tgttactgct aagtaccaac aagcagtgcg tgacatcgta gctcttgctg
   111421 ttcaagctgg tgtaccagtc ccaactttct cagcagctat tacttacttt gatagctacc
   111481 gttcagctga ccttccagct aacttgatcc aagcgcaacg tgactacttt ggtgcccaca
   111541 cttaccaacg taaagacaaa gaaggaacat tccactactc ttggtatgac gaaaaataag
   111601 taggtctgcc atggggaaac ggattttatt acttgagaaa gaacgaaatc tagctcattt
   111661 tttaagtttg gaactccaaa aagagcaata ccgagttgat caggttgagg aggggcaaaa
   111721 agccctctcc gtggctcttc agacagacta tgacttgatt ttattgaatg ctcatctggg
   111781 ggatatgaca gcacaggatt ttgcagacaa gctgagtcgg actaagccag cttcagtcat
   111841 catggtcttg gaccatcgcg aagaattgca agaagagctg gaagttgttc agcgttttgc
   111901 agtttcatac atctataagc cagtccttat cgaaaatctg gtagcgcgta tttcggcgat
   111961 cttccgaggt cgggacttca ttgatcaaca ctgcagtctg atgaaagttc caaggaccta
   112021 ccgcaatctt aggatagatg ttgaacatca cacggtttat cgtggtgaag agatgattgc
   112081 tctgacccgc cgtgagtatg accttttggc gacacttatg ggaagcaaga aagtattgac
   112141 tcgtgagcaa ttgttggaaa gtgtttggaa gtatggaagt gcgaccgaga caaatatcgt
   112201 agatgtctat atccgctatc tacggagcaa gcttgatgtt aaaggccaaa aaagctacat
   112261 taaaaccgtg cgtggtgttg gttacaccat gcaataatag aaaagcagtt gcagttgtgt
   112321 aactgctttt ttgaggagtt tttatatatt gacatgcagt cgggtctttg ctacaatcgt
   112381 tttaggaggg tatatagatg aaaattttga aaaaaatgat gcaagttcta ctagcagtct
   112441 ttttctttgg tttgctagct acaaatacgg tatttgcgaa taccacaggt ggccgattta
   112501 ttgataagga taatagaaaa tattatgtaa aagatgatca taaagcaatc tattggcata
   112561 aaatagacgg taaaacctac tattttggtg atggaggaga gatggttgtc ggttggcaat
   112621 acttagaaat tcctggaaca ggttatcgtg ataatttatt cgataaccaa ccagttaatg
   112681 aaattggcct tcaggagaag tggtactatt ttggacaaga tggtgctttg ctagaacaaa
   112741 cagataaaca agtactagag gcaaaaacgt ctgaaaatac aggaaaagta tacggtgaac
   112801 aatatcctct atctgctgaa aagagaactt attattttga taataattat gctgtaaaga
   112861 caggctggat ttatgaagag ggtcattggt attatttaaa taagctagga aattttggcg
   112921 atgattctta caatccacta ccaattggtg aagttgctaa gggttggact caagattttc
   112981 atgttactat taacattgat agaagcaaac ctgctccatg gtactaccta gatgcttcag
   113041 gtaagatgct tacagattgg caaaaagtaa acggaaaatg gtattatttt ggctcctctg
   113101 gttctatggc aacaggttgg aaatatgtac gaggcaaatg gtattactta gataataaaa
   113161 atggtgatat gaagactggt tggtatcaag atggttcaac ttggtactat ttagatcctt
   113221 ctaatggaga tatgaaaata ggttggacaa aagtaaatgg aaaatggtat tatctcaatt
   113281 caaatggagc aatggttaca ggtagtcaaa ctatcgatgg taaagtttat aacttcgctt
   113341 catctggtga gtggatttaa tgttggagga tatataaaat gaagcttttg aaaaaaacta
   113401 tgcaagctgg actaacagta attttctttg gtttgctagc tacgaataca gtatttgcag
   113461 ataactctga aggatggcag tttgtccaag aaaacggtag aacctattac aaaaaggggg
   113521 atctaaaaga aacctactgg cgagtgattg atggtaagta ctattatttt gattctctat
   113581 ctggagagat ggttgtcggc tggcaatata tcccgtttcc atctaaaggt agtacaattg
   113641 gtccttaccc aaatggtatc agattagaag gttttccaaa gtcagagtgg tactacttcg
   113701 ataaaaatgg agtgctacaa gagtttgttg gttggaaaac attagagatt aaaactaaag
   113761 acagtgttgg aagaaagtac ggggaaaaac gtgaagattc agaagataaa gaagagaaac
   113821 gttattatac gaactattac tttaatcaaa atcattcttt agagacaggt tggctttatg
   113881 atcagtctaa ctggtattat ctagctaaga cggaaattaa tggagaaaac taccttggtg
   113941 gtgaaagacg tgcggggtgg ataaacgatg attcgacttg gtactattta gatccaacaa
   114001 ctggtattat gcaaacaggt tggcaatatc taggtaataa gtggtactac ctccgttcct
   114061 caggagcaat ggccactggc tggtatcagg aaggtaccac ttggtattat ttagaccagc
   114121 caaatggcga tatgaaaaca ggctggcaaa accttgggaa caaatggtac tatctccgtt
   114181 catcaggagc tatggcaact ggttggtatc aagatggttc aacttggtac tacctaaatg
   114241 caggtaatgg agacatgaag acaggttggt tccaggtcaa tggcaactgg tactatgctt
   114301 atagctcagg tgctttggca gtgaatacga ccgtagatgg ctattctgtc aactataatg
   114361 gcgaatgggt tcggtaatga cagggcgctt ataattatat tagaacactc gcttaatcaa
   114421 agaagtgact ttgttgtact tgacctgacg attggggaga ttaaaagcat gtgaaatcta
   114481 cacatgcttt ttcgttagtt atgagtgttg aacttgacta accattgaca aaagataaga
   114541 gcaattaaaa taagatacaa aaatatcgat gctaactgca ccgaaacgcc cgatgctatg
   114601 gatagggcta atagggagag cagggacggg gcgagaatgt ccactgtgct cagagcagag
   114661 cccaccgtcc ccatcttgtc actggggata tgggcaaaga cagctgcttg taggcgaggg
   114721 ctgagaatgc cgataatcgt agaactgatg aaactggtca tgaaaattac gatataggct
   114781 tgacaaagga tactagttat tagagtcaat agggaaatct cacagaaaac caagaggtgc
   114841 gtgaaacgga tatttttaaa tagattactg ctggtcatat tgccaaggat agctccacaa
   114901 gacatgatga tggagagcag ggcgaagagt tgcccaatgc tcagttgtgc tagtgtctgt
   114961 tggatgaagc ggagggcaat cagccgaggg gacacatcca agatggcaat catactggtc
   115021 gtcagaaaca gtagtatgac ggtatctttt aacctcagga gcacagccag cgactgttta
   115081 agatgttgaa aatatttctt aaaactcagt gctgtatgtg acatttcaat ccttttttca
   115141 acctcataca aggtatgtcg aataacatac aggcccaaaa aggcaatgac aaaagtcaga
   115201 gtgttgataa gggaaatagt ttgaatactt ataacattga taaggaatgc gccagccaga
   115261 ttggcgacaa tgcggacaac cctcatcaga gactgcctga accccatggc atcatgcagg
   115321 tcgtccttaa ttacactgat gtagagggcg ttcatcatgt aggcagacag gtagctcaag
   115381 gtgtcagaga tgaggttgat gatgacaatc ataatgactg aaactaatga aaagggcgac
   115441 aagacgagaa atactgtcaa aatagcgtag agcaggattt tgattttggc aatacagagt
   115501 gcgtgtttga ctctattttc ttgaaaatct cctagaatcc tgagaaagag ttgcgatagt
   115561 aggggaacca tctctgaaat ggaaatcagt aaaatcgcta gcggagcgaa attgtactga
   115621 gccacataat tgataatggc gaggtagaaa atactgtcgc cgaatgatga aaaacagctg
   115681 tttagcagca actgtctata tatgttgttt gtccaaaata atttcataca tttctcctta
   115741 tgtctgcaca tcgaatggga atttattatt taatagacac caatataccc catgcttcct
   115801 attccgaagt caaacaaatc tgctttacca ctatctcctt gaaacatcag taaaccgtga
   115861 tcatctcgtt cagaacatgc taaaattacc tgttggattt ttttcatcag taatttgttt
   115921 tgattgtaga cagtggtttg tagtaagcta gttattccgt ggcaatatcc tgtcatcatt
   115981 tttagatgat ggttaaaaac aaattcttga tatttactaa taatatcttt gtttccgtca
   116041 caatcgtaca tacaaagata taagattatt ccggaaattc cttcgcacca agaaagttat
   116101 aaatttccta aattttcagt attagaagta actttttcta ataatttttt taattcagta
   116161 tggaatgtat ggagatcatt atagaacata gaaggttcta agactttaga ataggcaaat
   116221 aaagcatatg caattccaca atattcatga gcaaagctat agtctaaaat gctttctttg
   116281 gctgtatctc tttgtaggaa ataatgataa atttccccat atactattgt ggatgaaagt
   116341 tttaagagta ttgtcattgg taaaatgata gtattttatt aatgataata ggacatcaga
   116401 ttttcccaat gcaaagtcta tttcctctag agtatcataa ttctctatta atttcttagc
   116461 ggtgacgttt gctaattgta gatagtattg atttttactg atagaaaata aatgtaggag
   116521 taactataga tagcctgcat caccaaatag cagtgagtat tgatattcat atgtgtgtgt
   116581 cgttctaatt gtcactgcct tcttgatgat agagagtatt ttagaatcca gttctggggg
   116641 gtacaattta tttagatgaa acagtagtcc agctattccg tgttggaatg ataaattact
   116701 tacgaaattt ccaaattctg ttgaagaagt gatccttcct tcagaattta cagttttatc
   116761 tagtaaaaat cgtagaacac tattacattc tgttttgtaa tcatatttat gttcctctat
   116821 ttttttaatt ttgactaatt atttgtttga cttaaattta gtagacattg taaccaaaat
   116881 agttgctcat ctgtgagctg accttgagta tgtgatagtt ctagtaattg aataggatcc
   116941 tttaggtaga ttcaatcaat ctataacaca acaacataat aatactttta ggataacttg
   117001 tcaaatatta tagtaaaatg aaataataac aggacaaatt gatcaggaca gtcaaatcga
   117061 tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaatcta ctatagtata
   117121 tatttttaca tcttgaattg tcaaattaag tgtataactt taccgtagca tacttcataa
   117181 ggcgttttcc acttaagaaa ttttcgtggt cgattattta gaacctgtat tcacaaaaaa
   117241 atgttaaact agagatatga tacgcaaagc atatgatact gatttaaacg atcaagagtg
   117301 ggcgaagatt gaaccctatt tctccaaaca ccgcacctat aaatggccga aacgagtact
   117361 tgttaatgag actttgtacg tcactaaaac aggttgtcaa tggcgcatgc tccctcacga
   117421 ctttcctctt tacttaatgg tatggagttt ctttcgtcgt tctatgacga caggttggtt
   117481 ccaggtcaat ggcagatggt actacgctta tagctcaggt gccttggcag tgaatacgac
   117541 tgtagatggc tattctgtca actataatgg tgaatgggtt cggtaatgaa agaagcgatt
   117601 gtgaatggaa acaatcgctt tttttgtgaa aatataataa aatagatagg aaagaattaa
   117661 tacttgtatg aaaaataaga cgttttttcg tctagtaaaa ggaaaaaatg acaaaaaaag
   117721 ttggtgtcgg tcaggcacat agtaagataa ttttaatagg ggaacatgcg gtcgtttacg
   117781 gttatcctgc catttccctg cctcttttgg aggtggaggt gacctgtaag gtagttcctg
   117841 cagagagtcc ttggcgcctt tatgaggagg ataccttgtc catggcggtt tatgcctcac
   117901 tggagtattt ggatatcaca gaagcctgca ttcgttgtga gattgactcg gctatccctg
   117961 agaaacgggg gatgggttcg tcagcggcta tcagcatagc ggccattcgt gcggtatttg
   118021 actactatca ggctgatctg tctcatgatg tactagaaat cttggtcaat cgagctgaaa
   118081 tgattgccca tatgaatcct agtggtttgg atgctaagac ctgtctcagt gaccaaccta
   118141 ttcgctttat caagaacgta ggatttacag aacttgagat ggatttatcc gcctatttgg
   118201 tgattgccga tacgggtgtt tatggtcata ctcgtgaagc catccaagtg gttcaaaata
   118261 agggcaagga tgccctaccg tttttgcatg ccttgggaga attaacccag caagcagaag
   118321 ttgcaatttc acaaaaagat gctgaaggac tgggacaaat cctcagtcaa gcgcatttac
   118381 atttaaaaga aattggagtc agtagccctg aggcagactt tttggttgaa acgactctta
   118441 gccatggtgc tctgggtgcc aagatgagcg gtggtgggct aggaggttgt atcatagcct
   118501 tggtaaccaa tttgacacac gcacaagaac tagcagaaag attagaagag aaaggagctg
   118561 ttcagacatg gatagagagc ctgtaacagt acgttcctac gcaaatattg ctattattaa
   118621 atattgggga aagaaaaaag aaaaagagat ggtgcctgct actagcagta tttctctaac
   118681 tttggaaaat atgtatacag agacgacctt gtcgccttta ccagccaatg taacagctga
   118741 cgaattttac atcaatggtc agctacaaaa tgaggtcgag catgccaaga tgagtaagat
   118801 tattgaccgt tatcgtccag ctggtgaggg ctttgtccgt atcgatactc aaaacaatat
   118861 gcctacggca gcgggcctgt cctcaagttc tagtggtttg tccgccctgg tcaaggcttg
   118921 taatgcttat ttcaagcttg gattggatag aagtcagttg gcacaggaag ccaaatttgc
   118981 ctcaggctct tcttctcgga gtttttatgg accactagga gcctgggata aggatagtgg
   119041 agaaatttac cctgtagaga cagacttgaa actagctatg attatgttgg tgctagagga
   119101 caagaaaaaa ccaatctcta gtcgtgacgg gatgaaactt tgtgtggaaa cctcgacgac
   119161 ttttgacgac tgggttcgtc agtctgagaa ggactatcag gatatgctga tttatctcaa
   119221 ggaaaatgat tttgccaaga ttggagaatt aacggagaaa aatgccctgg ctatgcatgc
   119281 tacgacaaag actgctagtc cagccttttc ttatctgacg gatgcctctt atgaggctat
   119341 ggcctttgtt cgccagcttc gtgagaaagg agaggcctgc tactttacca tggatgctgg
   119401 tcccaatgtt aaggtcttct gtcaggagaa agacttggag tatttgtcag aaattttcgg
   119461 tcagcgttat cgcttgattg tgtcaaaaac aaaggatttg agtcaagatg attgctgtta
   119521 aaacttgcgg aaaactctat tgggcaggtg aatatgctat tttagagcca gggcagttag
   119581 ctttgataaa ggatattccc atctatatga gggctgagat tgctttttct gacagctacc
   119641 gtatctattc agatatgttt gatttcgcag tggacttaag gcctaatcct gactacagct
   119701 tgattcaaga aacgattgct ttgatgggag acttcctcgc tgttcgcggt cagaatttaa
   119761 gacctttttc cctaaaaatc tgtggcaaaa tggaacgaga agggaaaaag tttggtctag
   119821 gttctagtgg cagcgtcgtt gtcttggttg tcaaggcttt actggctctc tataatcttt
   119881 cggttgatca gaatctcttg ttcaagctga ctagcgctgt cttgctcaag cgaggagaca
   119941 atggttccat gggcgacctt gcctgtattg tggcagagga tttggttctc taccagtcat
   120001 ttgatcgcca gaaggcggct gcttggttag aagaagaaaa cttggcgaca gttctggagc
   120061 gtgattgggg attttttatc tcacaagtga aaccaacttt agaatgtgat ttcttagtgg
   120121 gatggaccaa ggaagtggct gtatcgagtc acatggtcca gcaaatcaag caaaatatca
   120181 atcaaaattt tttaacttcc tcaaaagaaa cggtggtttc tttggtcgaa gccttggagc
   120241 aggggaaagc cgaaaaagtt atcgagcaag tagaagtagc cagcaagctt ttagaaggct
   120301 tgagtacaga tatttacacg cctttgctta gacagttgaa agaagccagt caagatttgc
   120361 aagctgttgc taagagtagc ggtgctggtg gtggtgactg tggtattgcc ttgagttttg
   120421 atgagcaatc aactgaaacc ctaaaaaatc gctgggccga tctggggatt gagctcttat
   120481 atcaagaaag gataggacat gacgacaaat cgtaaggacg agcatatccg ctatgctctt
   120541 gagcagaaaa gttcctataa tagctttgat gaggtggagc tgattcattc ttccttgcct
   120601 ctttacgacc tggatgaaat cgatctgtcg acagaatttg caggtcgcaa gtgggacttt
   120661 cctttctata tcaatgccat gacgggtgga agcgataagg gaaaagaaat caatcaaaag
   120721 ctggctcaag tggcagaaac ctgtggaatt ttatttgtga cgggttctta tagcgtagcc
   120781 ctcaaagatt cagcagatga ctctttttct gttaagtcta gccatccaaa tctccttctt
   120841 ggaaccaata ttggattgga caagtctgtc gagttaggtc ttcagactgt agaagagatg
   120901 actcctcttc tcctgcaagt gcatgtcaat gttatgcagg aattgctcat gcctgaggga
   120961 gaaaggaagt tcagaagctg gcaatcgcat ctggcagact atagcaaaca aatccctgtt
   121021 ccgattgtcc tcaaggaagt aggttttgga atggatgtga agaccatcga gagagcctat
   121081 gaattgggcg ttcgaacctt tgacctgtca ggtcgtggtg gcaccagctt tgcttatatc
   121141 gaaaatcgtc gcagtggcca acgtgattat ctcaatcaat ggggccaatc taccatgcaa
   121201 gcccttctca atgcccaaga ctggaaagac aaggtcgaac tcttggtcag tggtggcgtt
   121261 cggaatccgc tggatatgat taagtgtttg gtctttggtg ccaaggctgt aggactgtct
   121321 cgaacagttc tggaattgat tgaaagctac accgtcgaag aagtgattga cattgttcaa
   121381 ggctggaaag acgatctgcg tttgcttatg tgtgctctta attgtgctac catagcagat
   121441 ctgcaaaaag tagactatct tctttatgga aaattaaaag aagcaaaaga tcagatgaaa
   121501 aaggcgtaac caccgccttt tttccatctt cagactgagg tgactttttt gaattgtgat
   121561 aaaatagaag ggagaggatg aaactatgag aaaatttaaa atctttttat ttatcgaagt
   121621 ctgtcttttg acaggagctc tgattttgat ggtatcagag catttttcgc gttttctgct
   121681 gattctattc ctctttttgc ttttgattcg ctattacact ggtaaagagg gcaataatct
   121741 tctgttagtg gtggcaagca ttcttttctt tttcatcgtc atgctcaatc cttttgtgat
   121801 tctagctatt tttgttgcgg tcatctatag tctctttctt ctttacccga tgatgaacca
   121861 ggaaaaagag cagacaaatt tggtttttga agaggttgtg acggttaaga aggagaaaaa
   121921 tcgttggttt ggcaatctcc atcatttttc aagctaccag acttgcaagt ttgatgatat
   121981 caatctcttt cgtctcatgg gtagggacac tattcatctg gagagggtca tcctaaccaa
   122041 tcatgacaat gtcattatcc tcagaaagat ggtaggaacg actaaaatca ttgtacctgt
   122101 tgatgtggaa gtcagtctca gcgttaactg tctctatggt gatttgactt ttttcaacca
   122161 gcccaagcga gctctccgca atgaacacta tcatcaggaa acgaaagact atctcaagag
   122221 taacaagagc gtcaagattt tcttgaccgc tatgattggg gatgtggagg tggttagagg
   122281 atgaaaaaac aagcttatgt aatcattgct ctcacctcct ttctgtttgt cttatttttc
   122341 tcccacagct tgctggacat ccttgacttt gactggtcta tctttctgca cgatgtcgaa
   122401 aaaacagaaa aatttgtctt tttattgttg gtattcagca tgtccatgac ctgtctccta
   122461 gctctgtttt ggcgaggtgt cgaagagctt tctctaagaa aaatgcaggc taatcttaag
   122521 cgtttgttgg cagggcaaga agtggttcag cttgcagatc cagatttgga tgccagtttc
   122581 aagtccttgt caggtaaact taacctcttg acagaagctc ttcaaaaggc tgaaaatcac
   122641 agcctttctc gggaagagga aatcatcgag aaagaacgga agcggattgc tcgggatttg
   122701 cacgatacag tcagtcagga gttgtttgcg gcccatatga ttttgtcagg tgtcagtcag
   122761 cagtctttga aattggatag agaaaagatg cagacccagt tgcagagtgt cacagctatt
   122821 ttagaaaccg cccagaagga tttgagagtc ttgctcctgc atttgcgacc ggttgaattg
   122881 gaacagaaga gtctggttga agggattcaa gtcctcttaa aagagcttga ggacaagagt
   122941 gatctcaagg ttagttttaa gcaaaatgtg acgaaattac ctaaaaaaat cgaggagcat
   123001 atcttccgta ttctgcaaga attgatcagc aatactctcc gccatgctca ggcctcttgt
   123061 ttggatgtct atctctatca gacggatctt gaattgcaac tgaaggtggt ggataatggg
   123121 attggtttcc agtcggggag cttcgatgat ttgagttatg gactccgcaa tatcaaggag
   123181 cgggttgaag atatggcagg aacggttcag ttattaacag ctcccaagca agggctggca
   123241 gttgatatcc gtattccctt gctcgataag gaatgataaa ggagtaaaga tgaaaatttt
   123301 actagtagat gaccatgaaa tggtccgatt gggcttgaaa agctactttg acctccaaga
   123361 cgatgtagaa gttgtgggtg aagcatccaa cggatctcag ggcattgact tggccttgga
   123421 attacgtcca gatgtcattg tcatggatat cgtcatgcct gagatgaatg ggattgatgc
   123481 gaccttgact atcctcaaag aatggcctga agccaagatt ttgattgtga gctcttactt
   123541 ggacaatgaa aaaataatgc cggttttgaa tgctggtgcc aaaggctata tgctcaagac
   123601 ttctagtgca gatgaattgc ttcacgctgt ccgtaaggtg gctgctggcg agttggccat
   123661 tgagcaagag gtcagcaaga aggtcgaata ccaccgcaat catatggagc ttcatgagga
   123721 cctgactgcg cgtgagcgag atgtactaca actcatcgcc aagggctacg aaaatcagcg
   123781 tatcgcagac gaacttttta tctctctcaa gacggttaag acccacgtgt ccaacattct
   123841 tgccaaactt gaagtcagcg atcgtaccca ggcggctgtc tatgcctttc agcaccactt
   123901 ggtggggcgg gaagattttt aattgttata taagaataat attgaggaaa tgattgagtt
   123961 gagtaccaaa gaagtgagca agtacctcta gcatggttga aaagcgcagt cattacttga
   124021 aaaaagtcgc tcgtttatgt cataatagag gatatttaaa gaaggcggta gatttcttga
   124081 ttctatagta gattgagaaa tttagaatgg tatgctataa ttacattagg aggatagaat
   124141 aatgaagaaa actttttata aaaaattggg tatttcaatt attgcgagta ctttattggc
   124201 tagccagtta tcgacagtat ctgctttgac tgttatttct agtacaggtg aagaatatga
   124261 ggtaagtgag acattacaga aaagtccagg aactaataat ttgtcacttc ctgagatttc
   124321 gccaacttat ggtcaatatt atacaaatca gtcagaagtc attattggca aaaatgattt
   124381 agttaaagta aaaaatactt tacaatatcc ttactctaca tcagcttatg taaaagcaac
   124441 attcaaaatt aaaaatgccg attcagtaga aataggtaca ggtagaggaa gtgcttcctt
   124501 tatcaaagac aatgttttga ttacagcagc tcatgtcgtt tatgaccgtg aatccaaaac
   124561 agaagcgact gaagtagaga ttatgcctgc ggctactcca gatagtaatc catttggtga
   124621 aataaaagtc aaagaagttc gttatttaaa agaatttcga aatactgctc caaatgagct
   124681 tactacctat gacttagcag ttttaatttt ggaagaaccg attggtgctc aattggggac
   124741 gttaggactt cccaataatt tagaaaatac taaaaatcta gatgtaacag ttacgggata
   124801 ttctgctgtt aataagggta ttaagcagat gtatactgat acaaaaacga tacttcaaga
   124861 tacaaatgat tttttattct accaaataga tacaaagggt ggtgctagcg gttcagcagt
   124921 gtatgattct aataatagga ttgttggagt tcatactaat gggagtgacc ctgaacaaat
   124981 gaattatgct gttaagttaa atgagaaagc tctatctttc atctactctg ttattaaagg
   125041 gcattctatt gatggatgga agttgattag tgatacttgg tattattata agaatagtaa
   125101 taaacaaacg ggttggcaaa agataaatga tacatggtac tatctagatg cttcaggtaa
   125161 gatgcttaca gattggcaaa aagtaaacgg aaaatggtat tattttggct cctctggttc
   125221 tatggcaaca agttggaaat atgtaggagg aagatggtat tatttcgata agaccaatgg
   125281 tgatatgaag actggttggt ataaagatgg ctcaacatgg tactatctag atcctactaa
   125341 tggagacatg aaaaaaggtt ggataaaagt aggaggaaac tggtattatc tcaattcctc
   125401 tggagcaatg gttacaggta gccaaactat cgatggtaaa gtgtataatt tcgcctcatc
   125461 tggtgagtgg atttaatatt ggaggatata tagatgaaaa ttttgaaaaa aactatgcaa
   125521 gttggactga cagtattttt ctttggtttg ctagcgacaa gtacagtatt tgcgaatacc
   125581 acaggtggcc gatttgttga taaggataat agaaaatatt atgtaaaaga tgatcataaa
   125641 gcaatctatt ggcataaaat agacggtaaa acttactatt ttggtgataa aggagaaatg
   125701 gtagttggtt ggcaatacat agaaatccct gggacaggct atcgtgataa tttattagac
   125761 aaccaaccag ttaatgaaat tgcccttcag gagaagtggt actattttgg acaagatggt
   125821 gctttgctag aacaaacaga taaacaagta ctagaggcaa aaacgtctga aaacacagga
   125881 aaagtatacg gtgaacaata tactccatct gctgaaaaga gaacttatta ttttgataat
   125941 aattatgctg taaagacagg ttggatttat gaagagggtc attggtatta tttaaataag
   126001 ctaggaaatt ttggcgatga ttcgtacaat ccactaccaa ttggtgaagt tgctaagggt
   126061 tggactcaag attttcatgt tactattgac attgatagaa gcaaacctgc tccatggtat
   126121 tacctagacc cagaaactgg cattatgcaa acaggatggc aatatctagg taataactgg
   126181 tactatctcc gttcatcagg tgctatggca actggttggg tgaaagatgg ttcaacttgg
   126241 tattatctag atgctcaaaa tggtgatatg aagacaggtt gggcttatgt tggtaacagt
   126301 tggtactacc ttcgttcatc aggtgcaatg tctaccggtt gggtgaaaga tggttcaact
   126361 tggtactacc taaatgcaag taatggagat atgaagacag gctggttcca ggtcaatgga
   126421 aaatggtact atgcttatag ctcaggtgct ttagctgtta ataccacagt aggtggctac
   126481 tacgtcaact acaatggtga atggattaag taatgaaggc taattgtaaa ctgtgatgga
   126541 tacttaactt tttataatag gtggataaaa gtctttaaaa tagaaaaaaa cgcatattat
   126601 taggtgttca aaaaccttga taatatgcgt ttttgtagtg gaaagatttc ttctttagtt
   126661 gatttcctat cactattata taatgctttt tgatttcaat ctagtataaa gaaaaccaag
   126721 gagaaaccat acttccagca tgattgaaaa gcgcagtcat tacttgaaaa aagtcgctcg
   126781 tttatgttat aatagactgt atttaaaaaa ttttaaggag aaatgacaga atgtctgtat
   126841 catttgaaaa caaagaaaca aaccgtggtg tcttgacttt cactatctct caagaccaaa
   126901 tcaaaccaga attggatcgt gtcttcaact cagtgaagaa atctcttaat gttccaggtt
   126961 tccgtaaagg tcaccttcca cgtcctatct tcgacaaaaa atttggtgaa gagtcacttt
   127021 atcaagacgt tatgaacgct cttttgccaa acgcttatga agcagctgtt aaagaagctg
   127081 gtcttgaagt ggttgctcaa ccaaaaattg acgtaacttc aatggaaaaa ggtcaagact
   127141 gggttatcac tgctgaagtc gttacaaaac ctgaagtaaa attgggtgac tacaaaaacc
   127201 ttgaagtatc agtagatgta gaaaaagaag taactgacgc tgacgttgaa gagcgtattg
   127261 aacgcgaacg caacaacttg gctgaattgg ttatcaaaga agctgctgct gaaaacggcg
   127321 acactgttgt catcgacttc gttggttcta tcgacgatgt tgaatttgat ggcggaaaag
   127381 gtgaaaactt ctcacttgga cttggttcag gtcaattcat ccctggtttc gaagaccaat
   127441 tggtaggtca ctcagctggc gacactgttg atgttatcgt aacattccca gaagactacc
   127501 aagcagaaga ccttgcaggt aaagaagcta aattcgtaac aactatccac gaagtaaaag
   127561 ctaaagaagt tccagctctt gacgatgagc ttgcaaaaga catcgatgaa gaagttgaaa
   127621 cacttgctga attgaaagaa aaataccgca aggaattggc tgctgctaaa gaagaagctt
   127681 acaaagatgc agttgaaggt gcagcaatcg ataaagctgt agaaaacgct gaaatcgtag
   127741 aacttccaga agaaatgatt cacgaagaag ttcaccgttc agtaaacgaa ttccttggaa
   127801 acttgcaacg tcaaggtatc aaccctgaca tgtacttcca aatcactgga actactcaag
   127861 aagaccttca caatcaatac caagcagaag ctgagtcacg tactaagact aaccttgtta
   127921 tcgaagcagt tgccaaagct gaaggatttg acgcttcaga agaagaaatc caaaaagaag
   127981 ttgagcaatt ggcagcagac tacaacatgg aagttgcaca agtacaaagc ttgctttcag
   128041 ctgatatgtt gaaacacgat atcacaatca aaaaagctgt tgaattgatt acaagcacag
   128101 caacagtaaa ataatcttaa taaacaaaaa gcccacctga attggtgggt tttcttatgc
   128161 actattttcc aaaaatctct ttgaggtctg cgtctgtaat cccaatcatg gcggggatgc
   128221 tgtcccagtt ttcttcggtt agggtgtagg attgttcaga ggtacttgat gtggcagttt
   128281 cagagacagc ttgttgcttt tcttcaacat tttcaattag atcactgaag cgttcaatca
   128341 gataggtttt tctggcagtt ccgatatgtt gggtagcata gtcgaaggcc tgtaattcgc
   128401 ctagtaagat aagcttgctt ttggcgcgag taatggctgt gtagatgaga ttgcgctcca
   128461 gcatacgcct actagcactg gtgatcggta ggatgacaac agggaactca cttccctgtg
   128521 atttatggat gctcatggca taggccaggc gaatcttgta ccattcgtta cgtgggtaag
   128581 agacctcgtt gccatcaaaa tcaatgacaa tctcgtcttg tttcgactcg gtgtatttac
   128641 caggaatcag gtctgtgatg actcctaaat ctccattaaa gacattgatt tcagcatcgt
   128701 tgaccaggtg aatgaccttg tcgcccttac gaaagtggca ttggggagct tcaaaactaa
   128761 gttggtcttt ttgtggtgga ttaaggaggt cttgcatgag ctggttgatg gcatcaatcc
   128821 ctgcagtccc tcggtacatg ggagccagaa cctgaatatc acgagcaggg ataccacttc
   128881 tgagggcggc acctaagatt ttttcaatgg tagcaggaat atggccacta gcaatttcaa
   128941 agtaggaacg gtcagctttt ttctgggtga aatcggctgg caagatgccc tgtcgaattt
   129001 gactagctag ggtaacgatg gttgattctt cgctttgtcg ataaattttt tccaagcgag
   129061 tctgaggaat caaaggaata tgaagcagat ccgctagaac ctgtccagga ctgacagaag
   129121 gcaactggtc gctatctccc acgatgagaa ttttactgtt agaagagatg ttggagaaga
   129181 gttgattggc cagccaagta tccaccatgg aaaattcatc cacgatgata aagtcagcat
   129241 ccagataatc ttccagatga ctggtgtcat cgtcacctgt cattcctaaa tgacggtgta
   129301 tggtcgcact tggcaagcct gtcaattcat tcatacgtcg agcagctcga ccagttggag
   129361 cagcaagaag aatcggcaga ttgctttttt tcctgaggtc aagtccttct aaaagggcat
   129421 aaacagcgat gatcccattg ataacagttg tcttaccagt accaggtcca cctgtcagga
   129481 taaagacctt gttctggata gcatcacaga tagcttgttt ttgaatgcta tcatactcaa
   129541 tccccagttc ttcctcgata gtagcgatat gtttttgaat ggtttctaaa tcctggctct
   129601 tctgttttcc tttttcaagg atacgaacca agtgactgcg gatgccttcc tcagcgaaaa
   129661 agagactatt atcaaagatt ttggtatcaa tttgctgaac cttgtcttct tcaatcaggt
   129721 aggagagttc ttgggcaact tgactgggat ccagttctac ggggcgggaa gactcaagga
   129781 gagtaagggt ttgttctagc aaatcccgtg cttcaacata ggtgtcccct gtttccatac
   129841 aggcctgaaa aagactatga attagaccgg cacggaagcg ttcaggagcc tgactttcga
   129901 tgcctagttc ttccgctagt tggtcagcaa tagtaaagcc caaacccttg atatcctcga
   129961 ccaactggta gggataattt tcaaccacat caagggtttc ttccttgtaa aagtcttgaa
   130021 tttgaaaggc tagtttgttg ggaatgccgt agttggctag tttggccaaa accatctccg
   130081 ttccgtagtt gagacggaga gtggagacga aagcctcgcg attttttgca gagagtcctg
   130141 cgatgtcttc taacttttct gggtgttgca aaatttcgtc aatggtattg tcgccatagg
   130201 tgtccactat tttctgagct gtcttgagac caattccctt gaaatggcta cttgaaaagt
   130261 acttgaccaa gcccttgcta gttggttttg cacgttcata acggttgatt tgcagttgtt
   130321 ccccatactt ggagtgctgg acaatttgcc cccaaaaggt atagtcttct ccctcaatca
   130381 cgtcagccat ggtgccggta acaatgattt caaaatcatc aaaatcctct gcgtctgtat
   130441 cgtcgatttc taggagaagg atacgataaa aattgctggg attttcaaaa ataatccgtt
   130501 caatggttcc tgaaaaataa acttccataa gattcctttg cataaatagg tgagagttaa
   130561 tactcttcga aaatctcttc aaaccacgtc agcttcgcct tgccgtatat atgttactga
   130621 cttcgtcagt tctatctaca acctcaaagc agtgctttga gcaacctgcg gctagcttcc
   130681 tagtttgctc tttgattttc attgagtata actttgtttc tatcttaatc aaactgggta
   130741 gtgaataatc atattatcac gatagaagaa gaggctgaga ttgctgattc tcggcctctt
   130801 cgatttctta aaatgttccg atacgggtga ttggccagaa gcggaattta gcttcccctg
   130861 tgatatcttt tgctttgaag gtacctacgt ggcggctgtc gctcgaaacc aagcggtcgt
   130921 ctccgaggag aaggtattct ccttctggaa cagtaaagct aaagttggtg ttatagttga
   130981 catcgactgt gaaggattgg gctttttgag cgatacttct aaagaaagtt cctttatttc
   131041 cttcaaagcc cttgcctgag taagtgcttt ggagtttgtc gtccttgaag cgtttgatgt
   131101 agtctgctag gtaaggctcg tccgtctctt tgtcattgat gtaaagttta tcgttttcgt
   131161 aacggatggt gtcgccaggc attccgataa cacgtttgac gatgtcctta ttaccgtctt
   131221 cctcatgggc aaccacgata tcaaatcggt caatagggag atgtttgaca acaaagagga
   131281 tttcaccatc cgccagggta ggatccatgg aatgcccttc tacgcggaca ttactccaaa
   131341 aaaagatacg gctcaaagct agtaatgaca gaatcaggag gaacaatccc cactctttta
   131401 agaaattttt aaatgaattc ataacttacc tttctaagcg ttttttcgct ttttcagtat
   131461 ttttaaagtg tagcttggcg cagaagctga gtccctgcat accataggct tgcaaaatct
   131521 ggctagctac cttatcagaa gccgttccag ctccacttgg aagttgatag cccagttctc
   131581 gtcccagatt ttcaagattt tccagaaaga gatcacgcgc aatgatagaa gaaactgcga
   131641 cagccaagta tttgccctca gccttttctt ctaagctgat aggattactg aaacgattgg
   131701 cctcttgtgc caagtacttg tcataatttt tagcactggt aaaggcatca atcacaattt
   131761 tttcaggctg aacacctttt tgaaggagga gatagatagc ctgattatgg agggctacct
   131821 taacagaaac agcattgtag cggtctccga tgatctcgtt gtacttgctt ggtgagagaa
   131881 gcagtgcctg gtgctggatt ttttccttta ggataggggc aatctgacga atcttttggt
   131941 cggtcagagt cttagaatct cccacaccga gttttcgcaa gaagtcatgc tggtcaggtg
   132001 tgacaaagga agccacaact gcaagtccac caaagtagga accatttcca acctcatcag
   132061 tcccaatcaa aggaagattt tgatcgctgt tttcttctac aatttgatag ccaaagaaac
   132121 gagcgtattt ctcggccccc tcaccctgaa gcaagacctt tccagaagta tagatagaaa
   132181 ccgttgcttg aggtagtcgc aaaaagtagc gaatataggg attcttgctg ggagccagac
   132241 tggtttgata gtgttcaaga aaagactgaa tctccttttc gcttggtgtg agtgttatac
   132301 ttgccatagt ttctattgta ccacaaaagc agtaaaattt gtaaaaactg acaaaattag
   132361 cgaattttgg tataatatcg tgaggtgaat tttatggcaa atctaaatcg attcaaattt
   132421 acattcggga aaaaaacgtt aaccttgaca agcgagcatg ataatctctt tatggaggaa
   132481 atcgccaagg ttgcgacaga aaaataccaa gcaattaaag aacaaatgcc tagtgcagat
   132541 gatgaaacaa tcgctctttt gttggcagtc aactgtttat caactcagct cagtcgtgag
   132601 attgaatttg acgataagga gcaagaatta gaagaactgc gccacaagct tgtgacttgc
   132661 aagcaagaac agagcaagat tgaggattcc ttatgatttc actccttctt ctattggtct
   132721 tggcttgggg attttatatc ggctatcgga gaggcctgct cttacaggtt tattacctga
   132781 tttcagccat ggcatcggct tttatggctg gccagtttta taaggggctt ggagagcaat
   132841 tccatttatt gctcccttat gcaaatccgc aggaaggtca gggaactttc tttttcccat
   132901 cggatcaact ctttcagttg gataaggtct tttatgcagg tattggctac ttgcttgtat
   132961 ttgggattgt ctatagcatc ggtcggttgc ttggtctctt gttacactta cttcctagta
   133021 aaaaactggg tggtaagttg ttccaagttt cagcagggat cttgtccatg ttggtgacct
   133081 tatttgtctt gcaaatggcc ttgaccatct tggcgaccat ccccatggca gctatacaaa
   133141 atcctcttga aaagagtatc gtcgcaaaac acatcatcca gagcataccg gtaacaacta
   133201 gttggctcaa acaaatctgg gtgacaaatt taatcggata aaaagggcag gagttttcct
   133261 agccctttgt ttacagattt gactcgaatc tatcagaatg taaaaagcta atactcttcg
   133321 aaaatctctt caaaccacat cagcttccat ctgcaacctc aaaacactgt tttgagcaac
   133381 ctgcggctag cttcctagtt tgctctttga ttttcattga gtacaataca cctagacatt
   133441 caaagacaag gaaataaaga tgaataagaa aatattagaa acattagagt tcaataaggt
   133501 caaggccttg tttgagcccc atttgttgac cgagcagggc ttggagcaat tgagacagct
   133561 agctccaact gccaaagcgg ataaaatcaa acaggctttt gctgagatga aggaaatgca
   133621 ggctcttttc gtcgagcaac cgcatttcac tattctctca actaaggaaa ttgcaggagt
   133681 ctgcaagcgt ttggagatgg gggcggacct caatatcgag gagttcctac tcttgaagcg
   133741 cgtgcttctt gctagccgag aactgcaaag tttttatgcc aatctggaaa atgtcagctt
   133801 ggaagaatta gccctatggt ttgagaaatt acatgatttt ccgcaattac aaggaaatct
   133861 ccaagccttt aatgatgcag gtttcattga aaattttgcc agtgaagaat tggcgcgaat
   133921 ccgtcgaaaa atacatgata gcgagagtca ggtacgcggt gttttacaag acttgctcaa
   133981 gcaaaaagcg caaatgttga cggaaggaat tgttgctagc agaaatggcc gtcaggtttt
   134041 accagtcaaa aacacctacc gcaataagat tgcaggtgtc gttcatgata tttctgctag
   134101 tggaaacacc gtctatatcg aaccccgtga ggtagtcaaa ctgagcgaag aaattgctag
   134161 tctgcgagca gatgagcgct atgaaatgct tcgcattctc caagaaattt ctgagcgtgt
   134221 ccgccctcat gcggctgaga ttgctaatga cgcttggatt atcggtcatc tggacttgat
   134281 tcgtgccaag gttcgattta tccaagaaag acaagcagtc gtgcctcagc tgtcagaaaa
   134341 tcaagagatt caactgctcc atgtctgcca tcctttggtc aaaaatgccg tcgcaaatga
   134401 tgtccatttt ggtcaagatt taacagctat tgtcattaca ggtcccaata caggtgggaa
   134461 gaccatcatg ctcaaaactc tgggcttgac acaggtcatg gcccagtcag gattgccgat
   134521 tttagcagac aagggaagtc gtgttggtgt ttttgaagaa atctttgctg atattggaga
   134581 tgagcagtct attgagcaga gcttgtctac cttctctagc catatgacca atatcgtgga
   134641 tattcttggc aaggtcaacc aacattcact cttacttttg gatgagttgg gggctggtac
   134701 tgatccccaa gagggagcag cccttgccat ggctattctg gaggaccttc gcctgcgtca
   134761 aatcaagacc atggcgacga cccactatcc agaactcaag gcctacggta ttgagacagc
   134821 ctttgtgcaa aatgccagta tggagtttga tactgcaact cttcgcccga cctatcgctt
   134881 tatgcagggt gttcctggcc gaagtaatgc ctttgaaatt gccaaacgtc taggcctatc
   134941 tgaagttatc gtaggagatg ccagtcagca gatcgatcag gacaatgacg tcaatcgtat
   135001 cattgagcaa ctagaagagc agacgctgga aagccgcaaa cgcttggaca atatccgtga
   135061 ggtggagcaa gaaaatctca agatgaaccg tgcgctaaaa aaactctaca acgagcttaa
   135121 tcgtgaaaag gaaaccgagc ttaacaaggc gcgtgaacag gctgctgaga ttgtggatat
   135181 ggccctaagt gaaagtgacc agattctcaa aaatctccac agtaaatccc aactcaagcc
   135241 ccacgaaatc attgaagcca aggccaagtt gaaaaaattg gcttctgaaa aagtggactt
   135301 gtctaaaaat aaggtccttc aaaaggccaa aaaaaaacga gctccaaagg tgggagatga
   135361 tatcgtggtt ctcagttatg gtcagcgtgg taccttgact agtcagctca aggacgaccg
   135421 ctgggaagcc caagttggct tgattaagat gaccttggaa gagaaagagt ttgaccttgt
   135481 tcaagcccag caagaaaaac cagtcaagaa gaaacacgtc aatgttgtga aacgaacttc
   135541 tgggcgagga cctcaagcta gactggatct tcgaggcaag cgctatgaag aagccatgaa
   135601 tgagctagat gccttcatcg accaagcctt gcttaacaat atggctcaag ttgatatcat
   135661 ccatggtatc ggaacaggag tcatccgtga aggagttacc aaatacttgc aaagaaataa
   135721 acatgtcaag agtttcggct atgccccaca aaatgctgga ggcagtggtg cgactattgt
   135781 cacttttaaa ggatagcagt attctggact ttataaagta aaaactgttg aactaatttt
   135841 tactaataaa cacattgaca aaagccaaca ttttttgtaa aattagaatc aattaaatac
   135901 caacaccgaa tgaagtttaa tagaagtggg gaatcgtttg attttccatg actgtaaatg
   135961 gacggaactc tggagagacc gtaaaggcac cgaaggggca aggcaggcaa ctgctcaaac
   136021 tctcaggtaa aaggacagag ctaggataga cggcttttta gcatttatct aagcattcca
   136081 gagtacatgt atcttgcatg tgctctttct tttggggttg aaacgatagg agaaggaaat
   136141 gttagaattg cttaaatcaa tcgatgcttt tgtttgggga ccgcccctct tgattttatt
   136201 gctcggaaca gggatttacc taactattcg gctaggactc ttgcaggttt tgcgtctgcc
   136261 caaggccttt cagcttattt ttatccagga taagggacat ggtgatgtat ccagttttgc
   136321 agctctgtgt acagccttgg catcaactgt tggaacagga aatatcatag gagttgcgac
   136381 ggctatcaag gttggtggac caggagctct attttggatg tggatggcgg ctttctttgg
   136441 aatggctacc aagtatgcgg aaggactctt ggccatcaaa taccgcacca aggacgacca
   136501 aggtgcagta gcgggaggtc ccatgcacta tatccttcta gggatgggag aaaagtggcg
   136561 accacttgct gttttgtttg cagtagcagg agtattggtt gctctcttgg gaatcggaac
   136621 cttcacccaa gtcaactcga ttacagaatc tatccaaaat acaacgacga tttcgccagc
   136681 catcacagct ctcgtcttgt ctgtctttgt agcgattgca gtctttggtg gactcaagtc
   136741 tatttctaag gtttcaacta ctgttgttcc ttttatggcc atcatttata tcttaggaac
   136801 tcttacagtt attttcttta atatcggaaa aatccctgcc acaatcgctt tagtctttac
   136861 ctcagctttt agtccccttg ctgtggtagg tggatttgct ggtgctagcg ttcggatggc
   136921 tattcaaaat ggtgtggcgc gtggtgtgtt ctcaaacgaa tctggtctag gttctgctcc
   136981 tattgcagct gcagctgcca agacaaatga accagtagag caaggtttga tttccatgac
   137041 aggaaccttt attgataccc tcatcatttg tactctaact ggtttgacca tcttggtaac
   137101 tggagtttgg agtggtgact tgaatggggt tgccttgact cagtcagctt tctcaacagt
   137161 cttttcacac tttgggccgg ccctcttgac catcttcctt gtactttttg cctttacaac
   137221 gattctaggt tggaactatt acggagaacg ctgttttgag ttcctctttg gggttcgctt
   137281 tatctggctc taccgtgtgg tttttgtgct catggtcttg ttaggaggat ttatcgagtt
   137341 ggatatggtc tggattatcg cagatatcgt taacgccttg atggctctgc caaacttgat
   137401 tgccctcttg gtcttgtcgc cagtcgttat tgctgaaact aaaaagtatt ttgacaaata
   137461 atggaatcac acagctcgtg tgattttttt gcctataaat aatttttatc agcctgatat
   137521 ataatatata ttatacaagt gattggaagt gtgataaact aatataacaa cgaaaatctt
   137581 atgagagaat aaagctttat cttagataaa cttaggaatc aggattttat aagattttcc
   137641 aataatatta gtgtcaataa taagaaaaga ggtatcttat gacaacattt actatccata
   137701 cagtagagtc agcaccagca gaagtgaaag aaattcttga aacagtagaa aaagccaaca
   137761 atggctatat tcccaaccta atcggtctct tggccaatgc cccgactgtt ttagaagcct
   137821 accaaattgt ctcatctatc caccgtcgca acagtctgac acccgttgag cgtgaagtgg
   137881 tgcaaatcac ggcagccgtg accaatggtt gtgccttctg tgtcgcaggt cacacagcct
   137941 tttccatcaa acaaatccag atgaatgatg acttgattca agctcttcgc aatcgtactc
   138001 caattgaaac agatcctaaa ttggatacac tagctaagtt taccttggca gttatcaata
   138061 ccaagggtcg tgtaggagat gaagccttgt ctgagttttt agaagctggc tacactcaac
   138121 aaaatgcctt ggatgtggtt tttggtgtca gcctaacaat cctctgtaac tatgccaaca
   138181 acttagctaa tacaccaatt aatccagaat tgcaacctta tgcctaattc atatctgagt
   138241 aaaatgaagt ctgaaataag cggactgcgt ttttttaaat cctcatttaa gcgcttttat
   138301 gttatactga aactaacatg attattggag gttaggatga aaaaactccc cttagtattt
   138361 tcaggttgtt tgctaggttt ggcaggagct ggaaatctta ttttagatac gttgccggtt
   138421 ctatcccatc tttttagtct gactggtttg gttttatgga tttactttct aattctgcat
   138481 ctctttaatt ggaaagaaac caagcaagaa ttgaccaagc cccctctttt gtcaggaatg
   138541 gcaacctttc ctatggctgg gatgatttta tcgacctatg tctttcgcgt attctcttat
   138601 cttcctttgg tagcacaagg gatttggtgg ttttcatttc tcttggattt gaccttgatt
   138661 gctgacttta ccatcaagtt tgcttgtcca gggcggaggg ttcatgccac tccaagctgg
   138721 acggttctct atgtggggat agcagtggct gccttgacct atcctctggt aggtattatc
   138781 gaaattgcct atgcgacctt gagttttggt tttctcttga ccttctatct ctatcccctt
   138841 atttatagcg atttaaagaa acatccactc ccactagcct tgcttggaca agaaggaatc
   138901 tactgtgctc ctttctctct actcttggct tctctagttc gagtaggagg aaccagcctg
   138961 ccgacttggg tcttgattgt catgattttg gcttctcaat ccttcttttt ctttgtttta
   139021 actcgtctgc ccaacatttt aaaacaaggt tttcaaccag ccttctcagc cctcaccttc
   139081 ccaaccatta tcacagcgac ctcgctcaag atggctcagg gaattttgaa acttccattt
   139141 ctggattacc tggtattgac tgaaaccatt atatgcctaa ctattttatt ctttgtacta
   139201 ggtgcttatc tgatttggtt acgaaaaaag gtctagctag aaatagctaa accttatttt
   139261 ttatggtttg atgacttcag ctccacccat gtatggacga agtgcttctg ggatggtcac
   139321 agaaccatct tcattttggt aattttcaag aattgcagcc actgtacgtc caactgcaag
   139381 tccagaaccg ttcaaggtat gaaggagttt caccttgcca tctgcttcat cacggtaacg
   139441 ggtttgggca cgacgggctt ggaaatcttc tgtgtttgaa cagcttgaga tttcacggta
   139501 attgttttgt gctggaatcc acacttccaa gtcgtaagtc ttcgcagctg agaagcccat
   139561 atctccagta gagagagcaa cgacacggta tggaaggttg agtttttgaa gaatgttttc
   139621 agcgttggct gtcatttttt ccaattcttc gtaagattct tctggtttgg caaatttgac
   139681 catttcaacc ttgtggaatt ggtgcaaacg gatcaagcca cgcgtatcac gaccggcaga
   139741 accagcctca gaacggaatg acggactcat agcagtgaag tagattggaa gatctttgcc
   139801 gtctaagatt tcatcacggt agtagtttgt cagaggaact tcagcagttg gaatcaagac
   139861 aaagttggta tcgctgagtt caaaagtatc ttccttaaat tttggatact gaccagtacc
   139921 aaacatagaa tcatggttga ctatgtaagg tgtgatgact tcagtatagc cttcttttcc
   139981 atgttcatcc aacataaagt tgtagatagc acgttccaaa cgagcaccga ggcctttata
   140041 gaagaggaag cgagcgcctg ttaccttacc accgcgttcc cagtcaagga taccaaggtc
   140101 ttcaccgaga tcccagtgag ctttaggttc gaagtcaaac tcgcgtggag taccccaacg
   140161 gcgaacttcc acattgtcgt cttcgtcagc cccaacagga acgctgtcag ctgggatatt
   140221 tggaagagtc gttgtaaatt ctgtcaattt agcatcgatt tctgccaatt cagcatccaa
   140281 ggctttaacc tcagcagata gattttgcat ggcagcaatc ttgtcatctg tattttcctt
   140341 gttgcgctta gcttgggcaa tctcagcaga aactgtgtta cgttctgctt tgagagtttc
   140401 aaccttgacc aagatgttac gacgtttagc atcgatttct ttcatttcat tcaagacagc
   140461 agcatctaca ccacgtgtag ctaatttttc tgcgacagtt tcaaaatctg tacgaatacg
   140521 tttgatatct aacataagaa ctcctttatg aaaaaagcac gcctgacaaa acgttggagt
   140581 ggcagggcca cggttccatc caacttcaca ggtgtgcact tgattgtgta tgtaattgtt
   140641 actaacggta gaatttcacc tatccctcct atctgctcgc agtacccgca gactttctga
   140701 aagaagaaga taacctactt atccgttgct atgattatac taaagtttct acttttttgc
   140761 aaatagattt ttaaattttt ggctaattgt ctgaatcagg gtcggaagtt tgacgacctt
   140821 gtcattgcct agtttttcgc gtgcaatttt gagaatggca cctgagtctt ttgaagcaaa
   140881 gaggaatttt cctttgtctg taaagacttc gaagtggcgg ctgattttgc gtccagtgac
   140941 attggctcca atctgattga tatggctcca aggaatctgg ataaattgtt cgacattgac
   141001 atctgggtaa aattccaaag cctgatctcc gacaaggaat ttcccaactt tcccagcgat
   141061 agagaggtag gaagtgcctg tcgtactgag gagtactgtt ttgttaagtg attgggccat
   141121 gcttagtctt ccttactttc tccaaaaaag gcattgtaga gggctttaat tgctgctttc
   141181 tcttggtctt tattgacaac aaacataata gaaacttcac tagaaccttg agacatcatc
   141241 tggatgttga ttttgttttc agatagagcg cgtgtcgcag tagcagtcac tccgatacgg
   141301 ctcttcattt tttcaccaac aatcataatg atagaaaggt cgtgttcgat ttctgcatga
   141361 tctactttag ccttttgaac caactgacgc aggatttctt cttccttgat gggagttagt
   141421 tggcgagaac ggagaatgat agaaagatcg tcgatacctg ttggcatatg ttcccaaccg
   141481 atgttaagtt cttccaggat ttgcagaacc ttgcggccaa atccaatctc acggttcatg
   141541 aggtatttcg acatattaat gctgacaaag cctgagtcac cagcaattcc cacaactgga
   141601 aattcatcat tactgtgttt tagaacgata cgagtacctg gatggtcagg gttgttggta
   141661 ttcttgataa ccagaggaat ttttccacgg taggcaggaa gaagagcctc gtcatgaagg
   141721 actgagaagc ctgcataggc caactcgcgc atttcacggt aggtcaactc aggaatcgag
   141781 tgtggttggt ggataatacc agggtgggct gcaaagatac catcaacgtc cgtaaagttt
   141841 tcatagaggt cagctttgac accagcagca atgatagaac ctgtaatatc agatcctcca
   141901 cgtgagaaag tacagatttg attttcctta gtgacaccaa agaaaccagg aatgacaagg
   141961 acttcattgg tgtttgtcaa ttcttcaatc ttgtcataac ttgatggaat gatgcgagcg
   142021 tgaccaggtt cacttgtgac cataatccca gcttctctag ggtgcatata gcgtgcatca
   142081 ataccatttt ggttaaagta ggcagcaatc aatttggcat tgttattttc accggctgct
   142141 aggaaagtat cgtagagaaa ttcattttct tcaataggaa gagtggccaa ggcgtgaatg
   142201 cttttagaaa ttttttctag cacagctggt tttagtccca attcactaac catagcagca
   142261 tagcggtcga taatccagct ttggctcttg ctaatatcgt tacccgcaac atagtcgcgg
   142321 tagtatttaa tcagggcatc cgtaacctta gtatcttcag cattgcgttt accaggcgca
   142381 gaaacgacta caaaacgacg ctctgaatcg cttttaacga tatttaaaac tttttctaat
   142441 tgactagcag aggcaagaga actacctcca aatttaacaa ctttcataag aactcctaaa
   142501 gtaagtattc tatacgatta tagcagaaag aaaggctttt ttcaatgaag aaaatgcaat
   142561 cttgtttggg tgaaaaatga caagtatttt gataataact tgccaacatc tatcacttat
   142621 cggaatgtta aaaaagttag cgttttgctg ttcaaatttg taaaaata
//
LOCUS       DAVDZK010000002        84010 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVDZK010000002 DAVDZK010000000
VERSION     DAVDZK010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84010
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.002"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(86..1402)
                     /locus_tag="VUX16_000127"
     CDS             complement(86..1402)
                     /locus_tag="VUX16_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET8123190.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            1596..2822
                     /locus_tag="VUX16_000128"
     CDS             1596..2822
                     /locus_tag="VUX16_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HET8123191.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            3021..4595
                     /locus_tag="VUX16_000129"
     CDS             3021..4595
                     /locus_tag="VUX16_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET8123192.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVSPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFVDE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYCKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            4859..5647
                     /gene="codY"
                     /locus_tag="VUX16_000130"
     CDS             4859..5647
                     /gene="codY"
                     /locus_tag="VUX16_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET8123193.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDNYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            5647..6222
                     /locus_tag="VUX16_000131"
     CDS             5647..6222
                     /locus_tag="VUX16_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET8123194.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTGGRNLYGDLGIFYQEHDSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFSLGHFKNTLGAKLVDENLNELSE"
     gene            6304..6389
                     /locus_tag="VUX16_000132"
     tRNA            6304..6389
                     /locus_tag="VUX16_000132"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6338..6340,aa:Leu,seq:aag)
     gene            6672..7802
                     /gene="ugpC"
                     /locus_tag="VUX16_000133"
     CDS             6672..7802
                     /gene="ugpC"
                     /locus_tag="VUX16_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET8123195.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(7949..8095)
                     /locus_tag="VUX16_000134"
     CDS             complement(7949..8095)
                     /locus_tag="VUX16_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123196.1"
                     /translation="MEIKEQTRKLAVSCSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEY"
     gene            8303..9061
                     /locus_tag="VUX16_000135"
     CDS             8303..9061
                     /locus_tag="VUX16_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET8123197.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDAWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            9148..9660
                     /locus_tag="VUX16_000136"
     CDS             9148..9660
                     /locus_tag="VUX16_000136"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET8123198.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            9842..10786
                     /locus_tag="VUX16_000137"
     CDS             9842..10786
                     /locus_tag="VUX16_000137"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET8123199.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQNTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDEDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            10795..11472
                     /locus_tag="VUX16_000138"
     CDS             10795..11472
                     /locus_tag="VUX16_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET8123200.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            11571..12329
                     /locus_tag="VUX16_000139"
     CDS             11571..12329
                     /locus_tag="VUX16_000139"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET8123201.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIASP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLSAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            12367..13871
                     /gene="lytC"
                     /locus_tag="VUX16_000140"
                     /pseudo
     CDS             12367..13871
                     /gene="lytC"
                     /locus_tag="VUX16_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
     gene            14367..14885
                     /locus_tag="VUX16_000141"
     CDS             14367..14885
                     /locus_tag="VUX16_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET8123202.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            15015..15521
                     /locus_tag="VUX16_000142"
     CDS             15015..15521
                     /locus_tag="VUX16_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET8123203.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYILGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            15521..15691
                     /locus_tag="VUX16_000143"
     CDS             15521..15691
                     /locus_tag="VUX16_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123204.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            15723..16955
                     /gene="clpX"
                     /locus_tag="VUX16_000144"
     CDS             15723..16955
                     /gene="clpX"
                     /locus_tag="VUX16_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET8123205.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            16964..17551
                     /locus_tag="VUX16_000145"
     CDS             16964..17551
                     /locus_tag="VUX16_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET8123206.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            17562..17942
                     /locus_tag="VUX16_000146"
     CDS             17562..17942
                     /locus_tag="VUX16_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET8123207.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            17994..18884
                     /gene="rapZ"
                     /locus_tag="VUX16_000147"
     CDS             17994..18884
                     /gene="rapZ"
                     /locus_tag="VUX16_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET8123208.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKNLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NYPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            18881..19858
                     /locus_tag="VUX16_000148"
     CDS             18881..19858
                     /locus_tag="VUX16_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET8123209.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQIILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            19855..20766
                     /gene="whiA"
                     /locus_tag="VUX16_000149"
     CDS             19855..20766
                     /gene="whiA"
                     /locus_tag="VUX16_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET8123210.1"
                     /translation="MSFTVAIKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(20854..21981)
                     /locus_tag="VUX16_000150"
     CDS             complement(20854..21981)
                     /locus_tag="VUX16_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET8123211.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSENVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(22131..22727)
                     /locus_tag="VUX16_000151"
     CDS             complement(22131..22727)
                     /locus_tag="VUX16_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4190 domain-containing protein"
                     /protein_id="HET8123212.1"
                     /translation="MKQERKVLGILAIIFGALALLGSWMPIINNFSFILAILALIFGL
                     IGFAVNRKRPKTLAIIGTVLAVVSIAIVLVTQAMYAKSLKELGKNVEETVSSVSSSIE
                     SSQKEEDAKFNWTKEQFDALQVGDIINYGAGGTNYDDVASVHGEPNNVTTSSVNDHDS
                     KTVSYTSTGSKYKSVILSFSKQDDGSFLLTSKVSSGLE"
     gene            complement(22779..23159)
                     /locus_tag="VUX16_000152"
     CDS             complement(22779..23159)
                     /locus_tag="VUX16_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HET8123213.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHSSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTLSEYQNARLRCENEADRNMIHHLVKDALESLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLSLVN"
     gene            complement(23170..23337)
                     /locus_tag="VUX16_000153"
     CDS             complement(23170..23337)
                     /locus_tag="VUX16_000153"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123214.1"
                     /translation="MNHVQVKRPKENNSEYDYMLRLSNESIHQFEQKKKRQESQLKSY
                     PAIKSYYRVAN"
     gene            complement(23334..23810)
                     /locus_tag="VUX16_000154"
     CDS             complement(23334..23810)
                     /locus_tag="VUX16_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123215.1"
                     /translation="MTLAKLHFNDQGNLNGGILTNISLAQIQSTLVDNFPNSTTRTRN
                     FQALSTFLKNLDSNIITRIWLDGSFCTQKENPKDIDVLLFFKHSPDIEKYLKDIKEKA
                     STCLDIYQIGDKDHIEKTRPIYSHMAHNETYWMGQFGFDRNRNHKGIIELKTENLK"
     gene            complement(24086..24325)
                     /locus_tag="VUX16_000155"
     CDS             complement(24086..24325)
                     /locus_tag="VUX16_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123216.1"
                     /translation="MTITINFTEKNSYITDYLNKHGINTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPNPKTYTTDELLESLGMTREDIA"
     gene            complement(24325..24693)
                     /locus_tag="VUX16_000156"
     CDS             complement(24325..24693)
                     /locus_tag="VUX16_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8123217.1"
                     /translation="MFQTFDRIKELAKKQGLSINSLEEKLGYSRNTIYNLKSSKPSTE
                     RISEIADYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            24994..25185
                     /locus_tag="VUX16_000157"
     CDS             24994..25185
                     /locus_tag="VUX16_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123218.1"
                     /translation="MPNMDGGRQKIRDYLKEHNLTMATLAVQYSMARQDVTNILNGKL
                     KNPQANQFIARVIEDFKIR"
     gene            25212..25391
                     /locus_tag="VUX16_000158"
     CDS             25212..25391
                     /locus_tag="VUX16_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123219.1"
                     /translation="MEEDIRVHMPYEVFKNLLVRAGRIKREEGKQITWTNNTAPFTKE
                     QRREIDELYEQFAED"
     gene            complement(25367..25918)
                     /locus_tag="VUX16_000159"
     CDS             complement(25367..25918)
                     /locus_tag="VUX16_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123220.1"
                     /translation="MSEVFTTTLISVGATVLTNLIIHGFAYQQKKIENKNKLEEKKVD
                     FLNTQLSQDRDLYISTFQNFASISGKTVSYVESRLDDAPPIDLDIITNFDDIFYKTYL
                     FLDSDEEQKKFIYFRNVLRYQAGYPHPDGLYIWDVQFEEQSYDPDTIEEPRYIFDRLN
                     ECLLIANKHINDKLHIQSSANCS"
     gene            26166..26510
                     /locus_tag="VUX16_000160"
     CDS             26166..26510
                     /locus_tag="VUX16_000160"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123221.1"
                     /translation="MTDRELFKLPEDYVESTGLDKITFEVPFELFTKILKGYGHKLAW
                     EDFRQIKIHPSTRTKKTVGQCQFLFSIWMNDHLKPAIKPSKELQKEPVRKTKKQKRLH
                     KLAQNLLHRMKG"
     gene            26677..26880
                     /locus_tag="VUX16_000161"
     CDS             26677..26880
                     /locus_tag="VUX16_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123222.1"
                     /translation="MRPKRYPYSGKKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYKAIHDTSQVTQ"
     gene            complement(27035..27202)
                     /locus_tag="VUX16_000162"
     CDS             complement(27035..27202)
                     /locus_tag="VUX16_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HET8123223.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            27319..27462
                     /locus_tag="VUX16_000163"
     CDS             27319..27462
                     /locus_tag="VUX16_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123224.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            27459..27629
                     /locus_tag="VUX16_000164"
     CDS             27459..27629
                     /locus_tag="VUX16_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123225.1"
                     /translation="MKEAVKEFLKFRSRFTKIEWFEINQAIEARLNQKADQLKLDDLD
                     LEIISSRLEKVI"
     gene            complement(27622..27861)
                     /locus_tag="VUX16_000165"
     CDS             complement(27622..27861)
                     /locus_tag="VUX16_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123226.1"
                     /translation="MTEIHACLCGNWVNLSADDDCVMGPNMANPYIWWEENAELYSPI
                     SKPEANSMYHQDYIYIHYRGADYRIHPMFIQIVSR"
     gene            27980..28252
                     /locus_tag="VUX16_000166"
     CDS             27980..28252
                     /locus_tag="VUX16_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123227.1"
                     /translation="MEVVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETRKKMRSAG"
     gene            28249..28443
                     /locus_tag="VUX16_000167"
     CDS             28249..28443
                     /locus_tag="VUX16_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123228.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEK"
     gene            28440..28631
                     /locus_tag="VUX16_000168"
     CDS             28440..28631
                     /locus_tag="VUX16_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123229.1"
                     /translation="MMEYIYLVIIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMN
                     LRNSDKQFTYDVEPPEGLK"
     gene            28643..28984
                     /locus_tag="VUX16_000169"
     CDS             28643..28984
                     /locus_tag="VUX16_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123230.1"
                     /translation="MTQAEQIREYYREHPAASCDEVAEVVGTTKSNVSANLAKDIKAG
                     RCVRLEDKSYDYSPYFNHTQALTELVDWKNDTRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            28985..29215
                     /locus_tag="VUX16_000170"
     CDS             28985..29215
                     /locus_tag="VUX16_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123231.1"
                     /translation="MVRNKLTDLTNTLFAQLETLDDRDLTADELKTELQRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            29229..29951
                     /locus_tag="VUX16_000171"
     CDS             29229..29951
                     /locus_tag="VUX16_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HET8123232.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTTYTKTQIGEVRRRLGLPVGKV
                     YQGKLLTKEQHDYLVSIQKNKISRDVANEMNLKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNSGQFKKGNRPPNYVPVGTINYTTNGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKTGIGLTKLTNKIREVEKNG"
     gene            29944..30426
                     /locus_tag="VUX16_000172"
     CDS             29944..30426
                     /locus_tag="VUX16_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HET8123233.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKTDTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNITGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAKLVRTEKLVIK
                     "
     gene            30426..30785
                     /locus_tag="VUX16_000173"
     CDS             30426..30785
                     /locus_tag="VUX16_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123234.1"
                     /translation="MELMNKTRVTDSLAVVIGLESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPECKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            30785..31270
                     /locus_tag="VUX16_000174"
     CDS             30785..31270
                     /locus_tag="VUX16_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123235.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            31233..32426
                     /locus_tag="VUX16_000175"
     CDS             31233..32426
                     /locus_tag="VUX16_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HET8123236.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YRKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKSV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            32444..32761
                     /locus_tag="VUX16_000176"
     CDS             32444..32761
                     /locus_tag="VUX16_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123237.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            32761..33587
                     /locus_tag="VUX16_000177"
                     /pseudo
     CDS             32761..33587
                     /locus_tag="VUX16_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            33607..34113
                     /locus_tag="VUX16_000178"
     CDS             33607..34113
                     /locus_tag="VUX16_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123238.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALQRKAVGSYYNLVISVTKGKDGREFRNYDLEEEEAQPLTEAD
                     IDEDDLPF"
     gene            34286..35107
                     /locus_tag="VUX16_000179"
     CDS             34286..35107
                     /locus_tag="VUX16_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HET8123239.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIEFADKPAMTASEIE
                     RFWDGYPNANIALRTTNFFVIDIDKHGKENGFESLKKWEHLNLIEPTLQAKTASGGKH
                     LLYFKRDDEPITQMIKFLPGVDIKAHENNYIIVAPSATENGQYEWDLEKSAEGGTIVT
                     PSRDLIRAIKKQYGKTHGYRYDGKDGLRDLARRSQTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPNPLPEKEMMRTIESMIKKDRR"
     gene            35110..36447
                     /locus_tag="VUX16_000180"
     CDS             35110..36447
                     /locus_tag="VUX16_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET8123240.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMERATEKWDGRNRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQKEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKN"
     gene            36747..36902
                     /locus_tag="VUX16_000181"
     CDS             36747..36902
                     /locus_tag="VUX16_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123241.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KQEKLEE"
     gene            36899..37372
                     /locus_tag="VUX16_000182"
     CDS             36899..37372
                     /locus_tag="VUX16_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET8123242.1"
                     /translation="MNKQELIEKYKELENSSFDIAAIVVCQLILKDLEQLDEPKPVKV
                     QQFVADFIAEQKKLGHTLSYSIDASMSDIVAEWYWDNSELFALAWIFGYEVEEEKRYT
                     VVTKATKQPLYYNAMDKKLFFSMGGLATKFTRKQLKEADLGWVFDCEGIEIEEVE"
     gene            37372..37545
                     /locus_tag="VUX16_000183"
     CDS             37372..37545
                     /locus_tag="VUX16_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123243.1"
                     /translation="MEDEQNILETQLILGKQVLEIVLDLLKDDSKIGVVLPLNINDRE
                     FTITVEKEVTDRD"
     gene            37608..38498
                     /locus_tag="VUX16_000184"
     CDS             37608..38498
                     /locus_tag="VUX16_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET8123244.1"
                     /translation="MKFLNLFAGIGGFRLGMESAGHECIGFCEIDKFARASYKAIHDT
                     KGEIELHDITTVSDDTIRGIGSVDIICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILRPKYLFLENVKGLLNHENGVTFETIISTLDELGYNVEWQVLNSKNFGVPQNRER
                     VFIIGHLRRERTRRIFPLSGKNQSTSNQSVMKIGNINPSGNGMNGEVYQADGLAPTLT
                     TNKGEGQKIAINSYHENNHLSDGFRIRKLTPKECWRLQGFPDWTFDKAQEVNSNSQLY
                     KQAGNSVTVNVIAAIAKELS"
     gene            38599..39015
                     /locus_tag="VUX16_000185"
     CDS             38599..39015
                     /locus_tag="VUX16_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123245.1"
                     /translation="MIPKFRVWVKIGKRMVFSDDILAIDYENKEIVTQQVYFESGLAV
                     ERDIYCYDFDDIELMQSTGLKDKNGKEVFVGDIIKCTRGCLHEVYLEKEYGGTFIGGM
                     PSIYLKGLLNGYAWTEDEEIIDNVYENPELLEVTHE"
     gene            39008..39187
                     /locus_tag="VUX16_000186"
     CDS             39008..39187
                     /locus_tag="VUX16_000186"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123246.1"
                     /translation="MNKRQRKKKILNGLNKEERYHRTHCPVCDSEAGLFDRYFNTYGF
                     CSEYCGYEYYGISRL"
     gene            39208..39522
                     /locus_tag="VUX16_000187"
     CDS             39208..39522
                     /locus_tag="VUX16_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123247.1"
                     /translation="MTLFDEMQQLSSESHAKWFERYFEKYNLEQKLKTSAQKGYTGYL
                     INVWSVRDEYLRNRLGDERTLEALRELLGAGFTVKYKLYLSKNIFTGQDFVSNKKIHI
                     TW"
     gene            39597..40058
                     /locus_tag="VUX16_000188"
     CDS             39597..40058
                     /locus_tag="VUX16_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HET8123248.1"
                     /translation="MNKAKELLKELQNLDMDIQSRIDEINELEAGLLSSPKWSDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVINRKLQLGRMINRLKNPKHRTILRMTYINK
                     MYVDDICDSMRGISSPTYYRLKKQAVKELDIILSELIVNDSNCTGMKSKIC"
     gene            40083..40165
                     /locus_tag="VUX16_000189"
     tRNA            40083..40165
                     /locus_tag="VUX16_000189"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:40114..40116,aa:Tyr,seq:gta)
     gene            41290..41730
                     /locus_tag="VUX16_000190"
     CDS             41290..41730
                     /locus_tag="VUX16_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HET8123249.1"
                     /translation="MSGLRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHK
                     LLKNPKIKSYIDEQLKQLDSEKIADQQEVLSYLTSVMRGETQEQTLISIGELGQTITD
                     INVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            41708..43006
                     /locus_tag="VUX16_000191"
     CDS             41708..43006
                     /locus_tag="VUX16_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HET8123250.1"
                     /translation="MSQTYQIKQSDIVIDLPKTVGAGYGQFWRSRNLYRVVKGSRGSK
                     KSKTTALNYVVRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWIKRVFFDEETSRADTFATTTTYRCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDLANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAELRL
                     IEELRSEHGITRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            43018..44487
                     /locus_tag="VUX16_000192"
     CDS             43018..44487
                     /locus_tag="VUX16_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET8123251.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIRNTESSHLKKLKSYYL
                     GKHAILKHTRRNVNAPNYQTVANHAKDIADMATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGLTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKYQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMSLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNQD
                     NTKPEDEVEDEESGVLGEEESQSDLPTDGQGRKAGRPVR"
     gene            44396..45947
                     /locus_tag="VUX16_000193"
                     /pseudo
     CDS             44396..45947
                     /locus_tag="VUX16_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
     gene            46261..46785
                     /locus_tag="VUX16_000194"
     CDS             46261..46785
                     /locus_tag="VUX16_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HET8123252.1"
                     /translation="MSEEINATVSTESTETVDTQENVDTVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTNAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQT
                     VQQEVTEKWRKDFL"
     gene            46808..47833
                     /locus_tag="VUX16_000195"
     CDS             46808..47833
                     /locus_tag="VUX16_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HET8123253.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     INYVIARQAAEVVAPYLDELRFGAALGNVSDNVAMGKTAGANNAYNAVLDVSEKLDEL
                     GITKERLLFVTPSFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVPSKFLKG
                     VNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADS
                     KPAAKKSAQGKVVNRAKAWKTGTTYKKGESVTHADKVYVAVKDISNSATAPDTDTTNW
                     KEKTGKK"
     gene            47843..48031
                     /locus_tag="VUX16_000196"
     CDS             47843..48031
                     /locus_tag="VUX16_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123254.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNFASNGVA
                     ISDVLEEILPEPEFFEED"
     gene            48033..48344
                     /locus_tag="VUX16_000197"
     CDS             48033..48344
                     /locus_tag="VUX16_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HET8123255.1"
                     /translation="MSIELLKKMTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            48325..48663
                     /locus_tag="VUX16_000198"
     CDS             48325..48663
                     /locus_tag="VUX16_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123256.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYVKEAETIRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            48638..49150
                     /locus_tag="VUX16_000199"
     CDS             48638..49150
                     /locus_tag="VUX16_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET8123257.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNAAIKVVQADAR
                     RLAPARDGELIISIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQANHSGISPEV
                     SVTYKSNPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQI"
     gene            49150..49518
                     /locus_tag="VUX16_000200"
     CDS             49150..49518
                     /locus_tag="VUX16_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123258.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWENFPVVIFLEEQNKPGD
                     WFDDKEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            49521..49934
                     /locus_tag="VUX16_000201"
     CDS             49521..49934
                     /locus_tag="VUX16_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET8123259.1"
                     /translation="MLANGIKLAFSETKGNYQNLVGLKEVPEFGIEPEKVENTTLADT
                     VKKYEFGIGDAGELKYKFAYNNSSATAPYRVLRKAADGKKKLYFEQTYPDGTKVTFEG
                     QVSVKLGGGGVNAVIEFTLKIALQSELTFVDGIGG"
     gene            49939..50319
                     /locus_tag="VUX16_000202"
     CDS             49939..50319
                     /locus_tag="VUX16_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123260.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKGKKASKKKMTVVE"
     gene            50358..50708
                     /locus_tag="VUX16_000203"
     CDS             50358..50708
                     /locus_tag="VUX16_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123261.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYI
                     LSRMITNHVSLLLSNDAKIAELWEYAPDLFVEEKQAVEQERQRQALLLHKERMRDFAE
                     RHNRKRKEEVNGNS"
     gene            50695..51240
                     /locus_tag="VUX16_000204"
                     /pseudo
     CDS             50695..51240
                     /locus_tag="VUX16_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            52580..54301
                     /locus_tag="VUX16_000205"
                     /pseudo
     CDS             52580..54301
                     /locus_tag="VUX16_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841383.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            54310..54660
                     /locus_tag="VUX16_000206"
     CDS             54310..54660
                     /locus_tag="VUX16_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123262.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMLTQEEMSQLLNAVSAVFFEVSYPDPVKGQTTGTFYVGDRTAPSYSFTEK
                     FKPWSGAKFNLVER"
     gene            54665..57862
                     /locus_tag="VUX16_000207"
     CDS             54665..57862
                     /locus_tag="VUX16_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HET8123263.1"
                     /translation="MDALIRRQFDRAMFAKDRTLAIRVGDYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDILHPEIGLLVGTTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLYGL
                     TKSEIEYQISGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGIEAKIQAQIEAADKDSDQKVDKIKKDFNDQVELAKARAEEVKQE
                     LSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEVKRIGLDSVARLGAFKSQ
                     TTSAQTALSGDLDALKQTVTSEVNQASEYRRTTTEVLSRMTGQMDGFATKSEVRQDVA
                     GLTETFAKLKTDTNNLISGAKSEITLAKTEFQKTADGLSAKMSAVERYVNQDGQRQEA
                     LQRYTREESARQVSAVREQISRDYVGKSAYQEDVRGLERRFSAISTQTNNDIARKIAQ
                     YKQTVDGQFASITSQIAGKANQTDFQRVKETSKLYERILGNSKNGIANTIARMAMTHQ
                     LFQVEVSKNDHLKTVQRQLAGSWSVQNINSAGDLISGINLGANGHNRFVGKLTHITGE
                     TLIDRAVIKSAMVDKLKTANFEAGSVTTTILDAEAVTADKVRFDAAFIRKMTANDAFI
                     DQLTSKRIFSTKVESVISSSTFLEAYQGRIGGFTIGRFAQGRGRWISGINQFSVGMGN
                     GEGGGYNGENTAFWANWGYSWNSPGPNAWYVTTSGNMYCRNGADFHGKVDFSNSSRAN
                     FYGNTTFSRSPVFSNGIELGSKDVFGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSD
                     RRLKENITDTAVKALDKINRLRMVAFDFIESKKHEEIGLIAQEAETIVPRIVSRDPEN
                     PDGYLHIDYTALVPYLIKAIQELNQKIEKMEKTIA"
     gene            57859..57975
                     /locus_tag="VUX16_000208"
     CDS             57859..57975
                     /locus_tag="VUX16_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="HET8123264.1"
                     /translation="MNNNMLTNIALKAIQELALENRKRTDRLENLENERRTA"
     gene            57956..58159
                     /locus_tag="VUX16_000209"
     CDS             57956..58159
                     /locus_tag="VUX16_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123265.1"
                     /translation="MNAEQLNQALQMTISEMSTTSTNSMITSNVLSIQLDEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            58162..58512
                     /locus_tag="VUX16_000210"
     CDS             58162..58512
                     /locus_tag="VUX16_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123266.1"
                     /translation="MAKTIQNTDNLLDLTKITEPFDLASALRYMKESGEFIRCKNVND
                     DFYMYRDVQKRPVFVNGRRQFKDVETVWAFNQWGGTITTINVAILLNQEFYIMKFDAE
                     GNPDWTDPTVEPKE"
     gene            58521..58820
                     /locus_tag="VUX16_000211"
     CDS             58521..58820
                     /locus_tag="VUX16_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123267.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHAVGDIQKEMVRMNDRMEEIEKGE"
     gene            58824..59156
                     /locus_tag="VUX16_000212"
     CDS             58824..59156
                     /locus_tag="VUX16_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET8123268.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRAVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKIRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            59160..60116
                     /gene="lytA"
                     /locus_tag="VUX16_000213"
     CDS             59160..60116
                     /gene="lytA"
                     /locus_tag="VUX16_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET8123269.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKNTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(60369..61337)
                     /locus_tag="VUX16_000214"
     CDS             complement(60369..61337)
                     /locus_tag="VUX16_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET8123270.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFTPSQLLGDGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            61473..62330
                     /locus_tag="VUX16_000215"
     CDS             61473..62330
                     /locus_tag="VUX16_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET8123271.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKTIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            62317..63096
                     /locus_tag="VUX16_000216"
     CDS             62317..63096
                     /locus_tag="VUX16_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123272.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEALPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            63120..64472
                     /locus_tag="VUX16_000217"
     CDS             63120..64472
                     /locus_tag="VUX16_000217"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET8123273.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGELLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     KNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKKTGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            64546..64920
                     /locus_tag="VUX16_000218"
     CDS             64546..64920
                     /locus_tag="VUX16_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET8123274.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            64922..65770
                     /locus_tag="VUX16_000219"
     CDS             64922..65770
                     /locus_tag="VUX16_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET8123275.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASSQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            66047..66814
                     /locus_tag="VUX16_000220"
     CDS             66047..66814
                     /locus_tag="VUX16_000220"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET8123276.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            66826..68010
                     /locus_tag="VUX16_000221"
     CDS             66826..68010
                     /locus_tag="VUX16_000221"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET8123277.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSRDKLNRLFDLETDFTFESSEQAWSALLWALEIENAQSFLKFWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            68007..69878
                     /locus_tag="VUX16_000222"
     CDS             68007..69878
                     /locus_tag="VUX16_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET8123278.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHNLKKELSGGVAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQVKDRIGIVGDNGVGKSTLLNLIAGSLESTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKTFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIEALEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(70021..71205)
                     /gene="mntE"
                     /locus_tag="VUX16_000223"
     CDS             complement(70021..71205)
                     /gene="mntE"
                     /locus_tag="VUX16_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET8123279.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            71509..74205
                     /locus_tag="VUX16_000224"
     CDS             71509..74205
                     /locus_tag="VUX16_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET8123280.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVLLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKARDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHILTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            74218..75009
                     /gene="yghU"
                     /locus_tag="VUX16_000225"
                     /pseudo
     CDS             74218..75009
                     /gene="yghU"
                     /locus_tag="VUX16_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
     gene            75125..75535
                     /locus_tag="VUX16_000226"
     CDS             75125..75535
                     /locus_tag="VUX16_000226"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET8123281.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKCYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            75547..77142
                     /locus_tag="VUX16_000227"
     CDS             75547..77142
                     /locus_tag="VUX16_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123282.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            77208..77372
                     /locus_tag="VUX16_000228"
     CDS             77208..77372
                     /locus_tag="VUX16_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET8123283.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            77451..78179
                     /gene="yaaA"
                     /locus_tag="VUX16_000229"
     CDS             77451..78179
                     /gene="yaaA"
                     /locus_tag="VUX16_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET8123284.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVVGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(78546..79094)
                     /locus_tag="VUX16_000230"
     CDS             complement(78546..79094)
                     /locus_tag="VUX16_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET8123285.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGASALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQVVGDFTAARVNDSAWADGKL
                     VLEETVLNSLDKQAQDLVNAIK"
     gene            79415..79903
                     /locus_tag="VUX16_000231"
     CDS             79415..79903
                     /locus_tag="VUX16_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET8123286.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            79900..81087
                     /locus_tag="VUX16_000232"
     CDS             79900..81087
                     /locus_tag="VUX16_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET8123287.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     ENN"
     gene            81080..81445
                     /locus_tag="VUX16_000233"
     CDS             81080..81445
                     /locus_tag="VUX16_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET8123288.1"
                     /translation="MIDHFEIKVKDLQILEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            81461..82807
                     /gene="asnS"
                     /locus_tag="VUX16_000234"
     CDS             81461..82807
                     /gene="asnS"
                     /locus_tag="VUX16_000234"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET8123289.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            82960..83250
                     /locus_tag="VUX16_000235"
     CDS             82960..83250
                     /locus_tag="VUX16_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET8123290.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIKDFREGLYHIVNVEANDDVALKEFDRLSKINADILRHMIVKIDA"
     gene            83262..83732
                     /gene="ssbA"
                     /locus_tag="VUX16_000236"
     CDS             83262..83732
                     /gene="ssbA"
                     /locus_tag="VUX16_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET8123291.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTVGAYSAPTANYSAPTNSVPDFSRDENPFGATNPLDISDDDLPF"
     gene            83764..84003
                     /locus_tag="VUX16_000237"
     CDS             83764..84003
                     /locus_tag="VUX16_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET8123292.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
BASE COUNT        26140 a        15083 c        19100 g        23687 t
ORIGIN      
        1 cacaaaagag ggaaaagaca gatttggtgt ttcgtagaag taaaaacagc ccaaagaggg
       61 ctgtcagtta agatgagatt tcaacttaaa tcgcaaacaa gtcattcaag ttctcagcca
      121 aggttgggtg agtgaagatt tgttttgtga agtaagtgta aggaatcttg ttgtccatag
      181 caacagtaat gatgttgatg atttcttgag aaccttctga gaagatgctt gcaccaagaa
      241 tttcttttgt ttcagtatta acaacagctt tgaaagctcc gcgaaggtct ccatttacgt
      301 gaccacgagg catggctgca acagggattt ctttcactgc gtatggaagt ttcaaatcag
      361 ctgcttggct ttcagtcaaa ccaacttgtg aaagtgcagg tgtgatgaac atagtatttg
      421 gcacattgag acggtcctca agtgtgtagc tgccatctcc agcaaggtag ctataaacaa
      481 cacggaagtc atcaagtgaa atgtaagtaa attgaagacc accgttgaca tctccaactg
      541 caaagacacc aggaacgttt gtttgacagt gtttatctac tttaatagcg ccacgttcag
      601 ttagttcaat atctgtattt tcaagttgaa gtggttctac atttggtttg cgtccagttg
      661 cgtagagaag ggcgtcgaaa cggtaagttt cgtcttcagt tacgacaagc acttggtcac
      721 cgtcgttttt aatttcagta gtatggatat tttgaagcaa ttcaataccg tcttcttcca
      781 ggtattgttt agcaagagct gcgatggaag gttctgcacg aggtaggaat gtatccaagg
      841 catctaggac tgtaaccttg cttcctagtt tattgtaaag gccagcaaat tcaagaccga
      901 tatttccgcc accaaggact ccaagttttt caggcaattt atccaagctt tggatacctg
      961 ttgagtcaaa gacgtttttg cttgtagcaa gtccagggat tggcaagacg tttgaaacag
     1021 caccagtgtt gatgacgata gtttcagcag tcaattcttg tttttcatca ccagcttgga
     1081 tttcgatgac tttatttgaa aggaagtgag cttcagcatc aaagatattg acgccagtac
     1141 cagcaacagt cgtatagttt ttaccgttga ggcgaccagt gatcgtgttt ttggtagcaa
     1201 tgacttcttc aaaagacaag tctttctcag cagcaaccag caaagtttta gttgggatac
     1261 aaccgatgtt gatacaagtt ccaccgtaca tagctttgct acgttcaacg agggcaactt
     1321 ttttgccagc tgaagccaat ttaccagcta gtgttttacc agctttacca aatccgataa
     1381 cgattaaatc ataagttaac atttagaatt cctcctattc gaattacatt ctagcacaag
     1441 aaaaaaactt ttgcacaatt ctgctacgaa aaagacagaa aaagataaaa acgctttcca
     1501 gacaaaaaac tagtaatttt ttaacaagct tgataaacta aaatcctatc tatttttata
     1561 taagaaagaa taaatgttcg aaaataggag gttttatgaa atcgaatcgt tatattattg
     1621 cctttgctgg ggtcatttta cacttaatgc tgggttcgac ttatgcctgg agtgtttatc
     1681 gtaaccctat tattgaaaaa acgggatggg atcaggcttc tgttgccttt gcctttagtc
     1741 tagcaatctt ttgtttgggc ttatcggctg catttatggg gcgtttggta gaaaaatttg
     1801 gtccaaaagt catgggaagt ctatctgctt ttctatacgc aggtggaaat atcttaacag
     1861 gatttgcaat agaccgtcag gagctgtggt tgttgtatct cgcttatggc attttaggtg
     1921 ggcttggttt gggagcaggc tatattaccc ctgtgtcgac gattataaaa tggtttcctg
     1981 ataaacgtgg tctcgcaaca ggtttagcga ttatggggtt tggttttgct tctttattga
     2041 ctagtcccat agcgcaacac ctcatcgcag gggtagggct tgtagaaact ttttatattt
     2101 taggagcaag ttactttatt atcatgctcc tagcttcaca attcattaag cgtccaaatg
     2161 agcaagagct tgcaatttta tcttcttcag ggaaagaaaa aacagcctct ttgacgcaag
     2221 gaatggctgc aaatcaggct ctaaaaagca atcggtttta tatgctttgg attattttct
     2281 ttatcaacat agcttgtggt ttaggcttaa tttcagcggc atcgccaatg gcacaggaga
     2341 tggctggctt gtctacaagt catgcagcag taatggtggg tgttttgggg attttcaatg
     2401 gatttggtcg cttgctctgg gcgagtttgt ctgattatat cggtcgccct ctaaccttta
     2461 gtatattact gcttgtcaat cttttctttt ctctctcact ttggctcttt acagattccg
     2521 ttttatttgt agttgctatg tctattttga tgacttgcta tggagctggt ttttctttga
     2581 ttccagctta tctcagtgat atttttggaa ccaaggaatt ggccgctcta catggttata
     2641 ttttaacagc ttgggcaatg gctggtttag cgggacctat tttattagca gagacttata
     2701 aaatggctca ttcgtacaca caaaccttgt tcgtttttct cattttatac agtattgcct
     2761 tggctttgtc ttattatcta ggtcgttcaa tcaaaaaaga aagtcaaaaa ccgcttacat
     2821 gattttctgt agaaatgggg ctatcttttg ctctggtctt gtgttatact agataggttg
     2881 caaagaaaac agtacttttc ttttgtggaa aagaagcaac acgattttat atctagttat
     2941 atgaaaatac gtcataaaaa gaaaagtata aactaagccc tatagggtgg cttcgcacca
     3001 cctttagaaa gaagaataac gtgaaattta atgaattaaa cttgtctgct gatttgctgg
     3061 cagaaattga aaaagctggt tttgtagaag ctagtcctat ccaagaacaa actattcctt
     3121 tggcccttga aggcaaggat gttatcggtc aagctcagac tggtacagga aaaactgcag
     3181 cctttggctt gcctaccctt gaaaaaatcc gtacagaaga agcgactatc caagccttgg
     3241 tcatcgctcc aactcgtgaa ctagctgtcc aaagtcaaga agaactcttc cgctttggtc
     3301 gtagtaaggg agtcaaagtc cgttcagtat atggcggatc aagcattgaa aaacaaatta
     3361 aggctcttaa atctggtgcc catatcgtgg tgggaactcc aggtcgcctc ttggatttga
     3421 ttaaacgcaa ggccttgaaa ttacaaaaca ttgaaaccct tatccttgac gaagcggatg
     3481 aaatgcttaa catgggcttc cttgaagaca tcgaagccat tatttcccgt gtacctgaga
     3541 accgtcaaac tttgcttttc tcagcaacta tgccagatgc catcaaacgt atcggtgttc
     3601 agtttatgaa agcccctgaa catgtcaaga ttgcggctaa ggaattgaca acagaattgg
     3661 ttgaccagta ctatatccgt gttaaggaac aagaaaaatt tgacaccatg actcgtctca
     3721 tggatgtggc acaaccagaa ctcgctattg tatttggtcg taccaaacgc cgtgtggatg
     3781 aattgactcg tggtttgaaa attcgtggct tccgtgcaga aggaattcat ggcgacctag
     3841 accaaaacaa acgtcttcgt gtccttcgtg actttaaaaa tggcaatctt gatgttttgg
     3901 ttgcgacaga cgttgcagcg cgtggtttgg atatttcagg tgtgacccat gtctacaact
     3961 acgatattcc acaagatcct gagagttatg ttcaccgtat cggtcgtaca ggtcgtgctg
     4021 gtaagtcagg tcaatctatt acttttgttt ctccaaacga aatgggttac cttcaaatca
     4081 ttgaaaactt gactaagaaa cgcatgaaag gtctcaaacc tgcaagtgta gaagaatcct
     4141 tccaatcaaa aaaacaggta gctctcaaga aaatcgaacg tgattttgta gatgaaacca
     4201 ttcgtgccaa ctttgagaaa tttggtaagg atgctcgcaa attggctgct gagtttactc
     4261 cagaagaatt ggcaatgtat atcttgagtc tgacagtcca agatccagat agccttccag
     4321 aagtggagat tgcacgtgaa aaaccactac cgtttaaacc atcaggtaat ggtttcggtg
     4381 gtaaagctaa gggaggtcgt ggaggccgtc gtggggacga ccgtcgagag cgtgatcgcc
     4441 gtggcaatgg tcgccgtgat gagttcaaaa aaggaagtcg tggcaacgat cgttttgata
     4501 aggaaaaacg ttactgtaag gataataaaa aaccacgcaa tactttaagc gaaaagcaaa
     4561 caggctttgt tattcgtaac aagggcgata aataagaaaa agcggttcaa aatgaatcgc
     4621 ttttttatat aaggagaccg aatgtgaaaa agacaaataa atttattata ttatattgta
     4681 taatattatg atatgtaaaa taggcaactt gtcaatagaa aaggaacaat ttaattaaac
     4741 atattctggt ttttaattaa attgtaagtc aatgcaagtc aataaggaat tttcagataa
     4801 ttattgaaaa agagacgttt ttatgttata atgatagcga ttaaattcga ggtgaaaaat
     4861 ggcacattta ttagaaaaaa ctagaaaaat tacatcaatt ttgaaacgct cagaggagca
     4921 gttgcaggat gagcttcctt acaacgctat tacgcgtcag ttagcggata ttattcattg
     4981 caatgcctgc attatcaata gtaagggacg tctgcttggc tattttatgc gttataaaac
     5041 aaatacagat cgcgtagagc aattcttcca aactaagatt ttcccagata actacgttca
     5101 aggggctaat atgatttacg aaacagaagc aaacttgcct gttgagcatg atatgagtat
     5161 tttccctgtt gagagtagag atgattttcc agatggcttg acgactattg caccgattca
     5221 tgtatcgggg attcgccttg gttctttgat tatttggcgt aatgataaaa aattcgaaga
     5281 tgaggacttg gttcttgttg agattgccag taccgttgtt gggattcagc ttcttaactt
     5341 ccaacgtgaa gaagatgaga aaaatattcg tcgtcgtact gctgtcacca tggcggtcaa
     5401 taccctttct tactccgaac tccgtgctgt ttcagcaatt ttaggggaat taaatggaaa
     5461 tgaaggacag ttgactgcgt cagtgattgc agatcgtatc ggaattactc gctctgtgat
     5521 tgtcaatgct cttcgtaaac ttgagtctgc ggggattatt gaaagtcgct cacttggaat
     5581 gaagggaacc tatcttaagg tcttgatttc agatattttt gaagaagtga agaaaagaga
     5641 ttactaatga caaaggcttt aatttcgatt gattatacag aagattttgt tgctgatagt
     5701 gggaagctga cagcaggtgc tccagctcag gcgatttcgg atgccatcag caaggtaact
     5761 cgattagctt ttgaacgagg agattatatc ttctttacca ttgatgctca tgaagaaaac
     5821 gattgtttcc atccagaaag taaactattt cctcctcata atttgattgg gactggtgga
     5881 cgaaatttat acggagattt ggggatcttt tatcaagaac atgattcaga cagtcgtgtc
     5941 ttttggatgg ataaacgcca ttactcagct ttttcaggga ctgacctaga tattcgtttg
     6001 agagagcgta gagtgtctac cgttatctta acaggtgtct tgacggatat ctgtgtccta
     6061 catacagcta tagatgccta taatctagga tatgacatcg agattgttaa accagctgtt
     6121 gcttccattt ggcctgaaaa tcatcaattt tccctaggtc atttcaaaaa tacactcgga
     6181 gctaagttag tagatgaaaa tctaaatgaa ctttctgagt aatctggttg gcgaaaatga
     6241 aaaaatttga aaaaaagtgt tgacaagcat cccaaaagtt gatatactag taaagtaatc
     6301 gacgcgggga tggcggaatt ggcagacgcg caggactaag gatcctgtga ccgctttagg
     6361 tcgtgagggt tcaagtccct ctctccgcat aggaaaagag ttagctaaag ctagctcttt
     6421 tgtatttctc taaaaaatta gcatccagtc aaatgtagtg gagaatcatc gaaaatatga
     6481 gaaaactgat ccttgtttct gcttttgtca tagaagaata atcaagatta tcttcttcaa
     6541 attctccgat attctctaaa gttttgtgca agttgcacag aacttgttta tttttttggt
     6601 catcttgcca tagaaatata aagcgttttc atatataata taattatcaa aagacaaaag
     6661 gagttcacct catggtagaa ttgaatctta aaaatattta caaaaaatat ccaaacagcg
     6721 aacactactc agttgaagat ttcaacttga acatcaaaga taaagaattt atcgttttcg
     6781 taggaccttc aggatgtggt aaatcaacta cactccgtat gattgctggt cttgaagaca
     6841 ttacagaagg tactgcatct atcgatggcg tggttgtcaa cgacgtagct ccaaaagacc
     6901 gtgatatcgc catggtattc caaaactacg ctctttaccc acacatgact gtttatgaca
     6961 acatggcttt cggtttgaaa ttgcgtaaat acagcaaaga agacattaac aaacgtgttc
     7021 aagaagcagc tgaaatactt ggattgaaag aattcttgga acgtaaacca gctgaccttt
     7081 caggtggtca acgtcaacgt gttgccatgg ggcgtgcgat tgtccgtgat gcgaaagtat
     7141 tcttgatgga cgaacctttg tcaaacttgg atgccaaact tcgtgtatca atgcgtgctg
     7201 aaatcgctaa aattcaccgt cgtatcggag ctacaactat ctatgtaact cacgaccaaa
     7261 cagaagcgat gacacttgca gaccgtatcg ttattatgtc agctactaag aaccctgctg
     7321 gtacaggtac tatcggacgt gtagaacaaa tcggtactcc tcaagaagtt tacaaaaatc
     7381 cagttaacaa attcgttgca ggattcatcg gaagcccagc tatgaacttc atcaccgtga
     7441 aattggttgg tagcgaaatt gtttctgacg gtttccgttt gaaagtgcca gaaggagcat
     7501 tgaaagttct tcgtgaaaaa ggctacgaag gaaaagaatt gatctttggt atccgtccag
     7561 aagacgtgaa tgcagaacct gctttccttg aaacattccc agactgtgtt gtaaaagcga
     7621 ctatctctgt atcagaactg cttggttcag aatctcacct ttactgccaa gttggtaaag
     7681 acgagtttgt tgcaaaagtt gatgctcgtg actacttgca aacaggtgca acagttgagc
     7741 ttggatttga cttgaacaaa gcacacttct tcgatgtaga aactgaaaaa acaatctact
     7801 aaaataaata aaattcaaag cactacaaga aaagatatct ctttatcaat tgtagtggag
     7861 agatatcagt taatctaggg agagaaacaa aatgcttctc tcctttttgc tagggaagtc
     7921 atattatgca tctatattgt gatgctcttt aatactcttc gaaaatctct tcaaaccacg
     7981 tcaacgtcgc cttgccgtac gtatgattac tgacttcgtc agttttatct gcaacctcaa
     8041 agctgtactt tgagcagctt acggctagtt tcctagtttg ctctttgatt tccattgagt
     8101 attatttgtg ggtaccatct acaagtgaag ctatatgcgt aaactacgtg agcaattgaa
     8161 ttcgaactag agaggtaata ataaatttat gctatagtta tggtgacttg tatgcttttg
     8221 attctagttt atcaaataat agattagaat tgtcagataa tatcattttg tgttataatg
     8281 aagaaaaaac agaggtgttc aaatgtcaga agcaggtcat aagtttttag caaaattggg
     8341 gaaaaaacgc ttacgtccag gtggaaagcg tgccacagat tggttaattg cagaaggagg
     8401 attttcaaaa gaaaagagaa tactagaggt tgcgtgtaat aggggaacta cagcaattga
     8461 gttggcacag cgttttggtt gcaagataac tgctgttgat atggatgctc aagctttaga
     8521 agtggctaaa aaatctgctg gaacggcagg tgttgctcat ttaattagtt ttgaaagagc
     8581 aaatgcaatg aaacttcctt atcaagatgc tagttttgat attgttataa atgaagctat
     8641 gctgactatg caagccgatc aagctaagaa aaaatgtgta atggaatatc taagggtatt
     8701 aaaacctgga ggtcttctct tgacacatga tgtgcttctt aaggaagcta aagagtctat
     8761 cagacaggaa ttatcacaag caattcatgt aaatgtaggt cctttaactc aagatgcttg
     8821 ggaacaggtg atgatagaat caggttattg tgatgtgaaa gcattgactg gtgaaatgac
     8881 attaatgaaa ttatcgggta tgatttatga cgaaggtttg ctaggaactt tgaaaatttg
     8941 tgtaaatgct tgtaaaaagg agaatagaaa gcagttttta actatgtata aaatgtttgc
     9001 taagaataaa cagaaattgg gctttattgc gatggctagt tataaatcgt caaaacgtta
     9061 gataattatt gaagttaact tttccttttt tctttcttaa aaaatatgct ataatagaga
     9121 gtaaaaaact ttgaaagaaa gaaaaagatg aatttaaaag attacattgc aacaattgaa
     9181 aattatccaa aggaaggcat taccttccgt gatattagtc ctttgatggc tgatggaaat
     9241 gcttatagct acgctgttcg tgaaatcgtt cagtatgcta ctgacaagaa agtcgacatg
     9301 atcgtgggac ctgaagctcg tggatttatc gtgggttgtc cagttgcctt tgagttggga
     9361 attggttttg cgcctgttcg taagccaggt aaattgccac gcgaagttat ttctgctgac
     9421 tatgaaaaag agtacggtgt cgataccttg actatgcacg cggatgccat taagccaggt
     9481 caacgtgttc ttattgtaga tgaccttttg gcgacaggtg gaactgttaa ggcaactatc
     9541 gagatgattg aaaaacttgg tggtgttatg gcaggttgtg ccttccttgt tgaattggat
     9601 gaattgaacg gccgtgaaaa aattggtgac tacgactaca aagttcttat gcattattaa
     9661 tgaaaacagt ccttagggct gttttctcta cactaggata taaaaataga ctataactag
     9721 ttagagaaaa actataattg aaaactatat cttcttgcag tataataaaa ggactaagtg
     9781 tttgagattt gtcttcaaac atatgcaatt attcctgaaa gagtacagtt aggagagggt
     9841 tatgccgatt cgaattgata aaaaattgcc agctgttgag attttacgga cagagaatat
     9901 ctttgtcatg gatgatcaac gtgctgccca ccaagatatc cgtcctttga agattttaat
     9961 tttaaatctc atgccacaga aaatggtcac agagacccag ttgttgcgcc acttggctaa
    10021 tacaccccta caactggata ttgattttct ctatatggag agccaccgtt ctaaaacaac
    10081 tcgttcagag cacatggaga ccttctataa aacttttcct gaagtcaagg atgagtattt
    10141 tgatgggatg atcatcacgg gtgctccagt tgagcattta ccatttgagg aagtggacta
    10201 ttgggaggaa tttagacaga tgcttgagtg gtctaagact catgtctatt cgacccttca
    10261 tatctgttgg ggggctcagg ctgggcttta tctgcgctat ggtgtagaaa aataccagat
    10321 ggacagtaag ctatcaggta tttatcctca gaacacccta aaagagggtc accttctatt
    10381 tagaggcttt gatgatagct atgtatcccc tcattcacgg cacacggaga tttctaagga
    10441 agaggtctta aacaagacca atctcgagat tttatcagaa ggacctcagg ttggggtttc
    10501 tattttggcc agtcgtgatt tacgagaaat ttatagtttt ggtcatttgg agtatgaccg
    10561 tgataccttg gcaaaagagt attttcgaga tcgtgatgca ggtttcgacc cacatattcc
    10621 agaaaattac tttaaagatg aggatgttaa tcaggtacct tgtctttgtt ggtcttcatc
    10681 tgcagccctc tttttcagta attgggtaaa ccatgcggtc tatcaggaga cgccttttga
    10741 ttggagaaag atagaagatg atgcatctgc atatgggtat ttataagagg aattatgaca
    10801 tatttagacg cttttaaatc aggtaccttg gttttaccga gtgccctgct cttgcatttt
    10861 aaggaactct ttccttctag cgacgatttt ctggtttggc aatttttcta tttgcaaaat
    10921 acgacaggct tagaagaaat gtcgccaagc cagattgctg aaaggattgg caaggaaatt
    10981 tcggatgtca accagtccat ttctaatctg acggaaaggg gactgctcca gtatcgtact
    11041 atcgaattaa atggcgaaat tgaattgctc tttgatgcta gtttggcctt ggaacgtttg
    11101 gatgacctgt ttggagcagt tcattcaagt tcagaccagc tgacacctca aaaccagctc
    11161 aaggatttgg tggaaacctt ccagcaggag ttgggacgat tgttgacgcc ttttgagatt
    11221 gaggatttga ccaagacact aaaggaagat ggaaccagtg ctgacttgat taaggaggct
    11281 cttcgtgaag ctgttttgaa tggaaaacca aactggaagt acattcaggc gattttgaga
    11341 aactggcgcc atgaaggaat caagagtgtg gctcaaattg aggccaagag agcagaaaga
    11401 gaagcaagca atcctcagtt gacacaggta tctgcagatt tcagaaatgc catggatctc
    11461 tggaaggatt aatccatgca agcaggcttg aaatccgagt aagatttgca agctgtgtat
    11521 aattgtgata gaataaaata gaaaataaat tgaaaaaaga ggtatgtgaa atgtcacgta
    11581 aaccatttat cgctggtaac tggaaaatga acaaaaatcc agaagaagct aaagcattcg
    11641 ttgaagcagt tgcatcaaaa cttccttcat cagatcttgt tgaagcaggt atcgcttctc
    11701 cagctcttga tttgacaact gttcttgctg ttgcaaaagg ctcaaacctt aaagttgctg
    11761 ctcaaaactg ctactttgaa aatgcaggtg ctttcactgg tgaaactagc ccacaagttt
    11821 tgaaagaaat cggtactgac tacgttgtta tcggtcactc agaacgccgt gactacttcc
    11881 atgaaactga tgaagatatc aacaaaaaag caaaagcaat ctttgcgaac ggtatgcttc
    11941 caatcatctg ttgtggtgaa tcacttgaaa cttacgaagc tggtaaagct gctgaattcg
    12001 taggtgctca agtatctgct gcattggctg gattgagtgc tgaacaagtt gctgcctcag
    12061 ttatcgctta tgagccaatc tgggctatcg gtactggtaa atcagcttca caagacgatg
    12121 cacaaaaaat gtgtaaagtt gttcgtgacg ttgtagctgc tgactttggt caagaagtcg
    12181 cagacaaagt tcgtgttcaa tacggtggtt ctgttaaacc tgaaaatgtt gcttcataca
    12241 tggcttgccc agacgttgac ggtgcccttg taggtggtgc gtcacttgaa gctgaaagct
    12301 tcttggcttt gcttgacttt gtaaaataat cagtaagtag caaaagctag gtggaacagc
    12361 attcagatgt ctgttacatt ttttatagga gagaaagatt gaaaacaaaa attggattag
    12421 caagtatctg tttactaggc ttggcaacta gtcatgtcgc tgcaaatgaa actgaagtag
    12481 caaaaacttc gcaggataca acgacagctt caagtagttc agagcaaaat cagtcttcta
    12541 ataaaacgca aacgagcgca gaagtacaga ctaatgctgc tgcccactgg gatggggatt
    12601 attatgtaaa ggatgatggt tctaaagctc aaagtgaatg gatttttgac aactactata
    12661 aggcttggtt ttatattaat tcagatggtc gttactcgca gaatgaatgg catggaaatt
    12721 actacctgaa atcaggtgga tatatggccc aaaacgagtg gatctatgac agtaattaca
    12781 agagttggtt ttatctcaag tcagatgggg cttatgctca tcaagaatgg caattgattg
    12841 gaaataagtg gtactacttc aagaagtggg gttacatggc taaaagccaa tggcaaggaa
    12901 gttatttctt gaatggtcaa ggagctatga tgcaaaatga atggctctat gatccagcct
    12961 attctgctta tttttatcta aaatccgatg gaacttatgc taaccaagag tggcaaaaag
    13021 tgggcggcaa atggtactat ttcaagaagt ggggctatat ggctcggaat gagtggcaag
    13081 gcaactacta tttgactgga agtggtgcca tggcgactga cgaagtgatt atggatggta
    13141 ctcgctatat ctttgcggcc tctggtgagc tcaaagaaaa aaaagatttg aatgtcggct
    13201 gggttcacag agatggtaag cgctatttct ttaataatag agaagaacaa gtgggaaccg
    13261 aacatgctaa gaaagtcatt gatattagtg agcacaatgg tcgtatcaat gattggaaaa
    13321 aggttattga tgagaacgaa gtggatggtg tcattgttcg tctaggttat agcggtaaag
    13381 aagacaagga attggcgcat aacattaagg agttaaaccg tctgggaatt ccttatggtg
    13441 tctatctcta tacctatgct gaaaatgaga ccgatgctga gagtgacgct aaacagacca
    13501 ttgaacttat aaagaaatac aatatgaacc tgtcttaccc tatctattat gatgttgaga
    13561 attgggaata tgtaaataag agcaagagag ctccaagtga tacaggcact tgggttaaaa
    13621 tcatcaacaa gtacatggac acgatgaagc aggcgggtta tcaaaatgtg tatgtctata
    13681 gctatcgtag tttattacag acgcgtttaa aacacccaga tattttaaaa catgtaaact
    13741 gggtagcggc ctatacgaat gctttagaat gggaaaaccc tcattattca ggaaaaaaag
    13801 gttggcaata tacctcttct gaatacatga aaggaatcca agggcgcgta gatgtcagcg
    13861 tttggtatta agcgatgatt tgaaagaggg atgtgatagt agcaccctct ttttctttgt
    13921 tttatgatag ttcatcctcg agtaaattca agttcttgct cggaaatgaa gcttatatag
    13981 tagattgaat atagacaaat accttgtgat tggtaaaaca ttttagaaat tcatttacct
    14041 ttcctaatcg acttggtttc atcttatttc aatctattat agtattgggg aatttcttca
    14101 aaccacatca gcttggtcag ttctacctgc gacctcaaaa cttgtgcttt ggtcaagctg
    14161 ggtttagttt cctagtttgc tgatggattt ccattgacta taagcatcca accctctttt
    14221 tgtcttctaa agaattctta aattatcagt ctattgcaac ttttctcata taagttcttt
    14281 gtcttgctat tggttttcct tagtagtata ctaaggtagt aatcattaag aagtggttac
    14341 aaaaaataat gaatgaggta aagaaaatgg tagaattgaa aaaagaagca gtaaaagacg
    14401 taacatcatt gacaaaagca gcgccagtag cattggcaaa aacaaaggaa gtcttgaacc
    14461 aagctgttgc tgatttgtat gtagctcacg ttgctttgca ccaagtgcac tggtatatgc
    14521 atggtcgtgg tttccttgta tggcatccaa aaatggatga gtacatggaa gctcttgacg
    14581 gtcaattgga tgaaatcagt gaacgcttga ttacactcgg tggaagccca ttctctacat
    14641 tgacagagtt ccttcaaaat agtgaaatcg aagaagaagc tggtgaatac cgtaatgttg
    14701 aagaaagctt ggaacgtgtt cttgttatct accgttactt gtcagaactt ttccaaaaag
    14761 gtttggatgt cactgatgaa gaaggtgacg atgtgacaaa cggtatcttt gcaggcgcta
    14821 aaactgaaac agataaaaca atttggatgc ttgcagccga acttggacaa gcacctggtt
    14881 tgtaagaaat aaggaaacat agataaatct gtaggaaatt tcttacagat tttttctatt
    14941 ttgtaagcta ttccaaacca gtcttttttt gagttttttg ataaaatagt actatcagtg
    15001 aaaaggatgg aagcatgact aagaaaatcg tagctatttg ggcccaggat gaagagggtg
    15061 tgattggtaa ggaaaatcgt ctgccttggc atttgccagc agaattgcag cactttaaag
    15121 aaacaactct gaatcatgct atcttgatgg ggcgtgtgac ctttgatggg atggggcgtc
    15181 gcttgcttcc aaaacgggaa accttgattt tgacgcgtaa tccggaagaa aagatagatg
    15241 gggttgctac ttttcaggac gtccagtctg ttcttgactg gtatcaggct caagaaaaga
    15301 atctctacat tctcggtggg aagcaaattt ttcaggcttt tgaaccttac cttgatgaag
    15361 tgattgtcac tcacattcat gctcgggtgg aaggagatac ctatttccct gaagagcttg
    15421 acttgtctct ttttgagaca gtttcaagca aattttacgc caaagatgag aagaatcctt
    15481 atgattttac catccaatac cgcaagagaa aggaagtcta atggaacgga gtttatttgg
    15541 tctattcacg gcttttctgt gtttcatctg ctttctggca ggagcacagg cttttcgtaa
    15601 aaagcgttac gggctttcta tcctcctttg gttaaatgcc tttaccaatc tggtcaatag
    15661 tattcatgct ttttacatga ccttatttta gatagaatga cagtatagaa tggaaggaaa
    15721 tcatgtctac aaatagaaaa aatgatatga tggtttattg ctcattttgt ggcaaaaacc
    15781 aagaagaagt acaaaaaata attgctggca acaatgcttt tatttgtaat gaatgcgtgg
    15841 agttagctca ggaaatcatt cgagaagaat tggttgagga agtcttggca gacttatctg
    15901 aggtgccaaa accaattgaa ctcctccata tcttgaacca ctatgtaatt ggtcaagatc
    15961 gtgccaagcg tgccttggca gtggcggttt ataaccacta caaacgcatc aatttccacg
    16021 atacacgcga agagtcagaa gatgtggatt tgcagaagtc aaacattttg atgattggcc
    16081 caactggttc agggaaaact ttccttgccc agaccttggc taagagcttg aatgtacctt
    16141 ttgctattgc ggatgcgaca gctctgacgg aggctggtta tgtgggtgag gatgtggaaa
    16201 atatactcct caaactcttg caggttgctg actttaacat cgaacgtgca gagcgtggca
    16261 ttatctatgt ggatgaaatt gacaagattg ccaagaagag tgagaatgtg tctatcacac
    16321 gtgatgtttc tggtgaaggg gtgcaacaag cccttctcaa gattatcgag ggaactgttg
    16381 ctagcgtacc gcctcaaggt ggacgcaaac atccacaaca agagatgatt caagtggata
    16441 caaaaaatat cctcttcatc gtgggtggtg cttttgatgg tattgaagaa attgtcaaac
    16501 aacgtctggg tgaaaaagtc atcggatttg gtcaaaacaa taaggcgatt gacgaaaaca
    16561 gctcatacat gcaagaaatc atcgctgaag acattcaaaa atttggtatt atccctgagt
    16621 taattggacg cttgcctgtt tttgcggctc ttgagcaatt gaccgttgat gacttggttc
    16681 gcatcttgaa agagccaaga aatgccttgg tgaaacaata ccaaaccttg ctttcttatg
    16741 atgatgttga gttggaattt gacgacgaag cccttcaaga gattgctaat aaagcaatcg
    16801 aacggaagac aggggcgcgt ggacttcgct ccatcatcga agaaaccatg ctagatgtta
    16861 tgtttgaggt gccgagtcag gaaaatgtga aattggttcg catcactaaa gaaactgtcg
    16921 atggaacgga taaaccgatc ctagaaacag cctagaggtg actatggaac tgaatacaca
    16981 caatgctgaa atcttgctca gtgcagctaa taagtcccac tatccgcagg atgaactgcc
    17041 agagattgcc ctagcagggc gttcaaatgt tggtaaatcc agctttatca acactatgtt
    17101 gaaccgtaag aatctcgctc gtacatcagg aaaacctggt aaaacccagc tcctgaactt
    17161 ttttaacatt gatgacaaga tgcgctttgt ggatgtgcct ggttatggct atgctcgtgt
    17221 ttctaaaaag gaacgtgaaa agtgggggtg catgattgag gagtacttaa cgactcggga
    17281 aaatctccgt gcggttgtca gtctagttga ccttcgtcat gacccgtcag cagatgatgt
    17341 gcagatgtac gaatttctca agtattatga gattccagtc atcattgtgg cgaccaaggc
    17401 ggacaagatt cctcgtggta aatggaacaa gcatgaatca gcaatcaaaa agaaattaaa
    17461 ctttgaccca agtgacgatt tcatcctctt ttcatctgtc agcaaggcag ggatggatga
    17521 ggcttgggat gcaatcttag aaaaattgtg aggaaaagaa aatggcaaaa acaattcata
    17581 cagataaggc cccaaaggct atcgggccct atgttcaagg aaaaatcgtt ggcaaccttt
    17641 tgtttgctag cggtcaagtt cccctatccc ctgaaactgg ggaaattgta ggagagaata
    17701 tccaagaaca gacagagcaa gtcttgaaaa acatcggtgc tattttggca gaagcaggaa
    17761 cagactttga ccatgttgtc aaaacaactt gcttcttgag cgatatgaat gactttgttc
    17821 cttttaatga ggtttaccaa acggccttca aagaggaatt cccagctcgt tcagctgtgg
    17881 aggtagctcg tcttcctcgt gatgtaaaag tcgaaattga agtcatcgca gagattggat
    17941 aagctagttg aagtttggtg ttgccaaact tcttttgata taaggagaaa aagatgacaa
    18001 agaaacaact tcacttggtg attgtgacag ggatgagtgg cgcagggaaa actgtagcca
    18061 ttcagtcctt cgaggatcta ggttatttca ccattgataa tatgccgcca gctctcttgc
    18121 ctaagttttt gcagctggtt gaaattaagg aagacaatcc taagttggcc ttggtagtgg
    18181 atatgcgtag ccgttctttc ttttcagaga ttcaagctgt tttggatgag ttggaaaatc
    18241 aagatggttt ggatttcaaa atcctctttt tggatgcggc tgataaggaa ttggtcgctc
    18301 gttacaagga aaccagacgg agtcacccac tagcagcaga cggtcgtatt ttagatggaa
    18361 tcaagttgga acgtgaactc ttggcacctt tgaaaaatat gagccaaaat gtggtggata
    18421 cgactgaact cactccacgt gagctgcgca aaaaccttgc agagcagttt tcagaccaag
    18481 aacaagccca gtctttccgt atcgaagtca tgtctttcgg atttaagtat ggaatcccga
    18541 ttgatgcgga cttggtcttt gatgtccgtt tcttgccaaa tccctattat ctaccagaac
    18601 tgagaaacca aacgggtgtg gatgaacctg tttatgatta tgtcatgaac tatcctgagt
    18661 cagaagactt ttatcaacat ttattggcct tgattgagcc gattctgcca agttaccaaa
    18721 aggaaggtaa gtccgttttg accattgcca tgggatgtac gggtggacaa caccgtagtg
    18781 tggcatttgc taaacgcttg gtgcaggact tatccaagaa ttggtctgtt aatgaagggc
    18841 atcgcgacaa agaccgcaga aaggaaacgg taaaccgttc atgagaaaac caaagataac
    18901 ggtgattggt ggagggactg gaattcccgt cattctaaaa agtctgcggg aaaaagatgt
    18961 ggaaatcgca gctatcgtga cggtggcaga tgatggtggt tcttcaggtg aactccgaaa
    19021 aaatatgcaa cagttgacac cgccaggtga tcttcgtaat gtccttgtgg ccatgtcgga
    19081 tatgcctaag ttttatgaga aggtctttca gtatcggttc tctgaggatg ccggagcctt
    19141 tgctggccat ccattgggaa atctcatcat tgctggcttg tcagaaatgc agggttcaac
    19201 ctataatgcc atgcagttat tgagcaaatt tttccataca acagggaaaa tttatccttc
    19261 cagtgaccat cctttgaccc ttcatgcagt ctttcaggat gggacagaag tggctggaga
    19321 gagtcatatt gtagaccatc gaggcataat tgacaatgtc tatgtgacca atgccctaaa
    19381 cgatgatacg cctctggcca gccgtcgagt agtgcagatc atccttgaaa gtgacatgat
    19441 tgtcctaggg ccaggttccc tctttacctc tattttgccc aatatcgtga ttaaggaaat
    19501 tgggcgggct cttttggaaa ccaaggcaga aattgcctat gtctgcaata tcatgaccca
    19561 acgtggggag acggaacact ttacagatag cgaccacgtg gaagtcttgc atcgtcacct
    19621 tggtcgccct tttatcgaca ctgtcttggt gaatattgaa aaagtgcctc aggaatacat
    19681 gaattccaac cgttttgatg aatacttggt gcaagtggaa cacgattttg taggtctttg
    19741 taagcaagtt tcgcgcgtga tttcatctaa cttccttcgt ctggaaaatg gcggtgcctt
    19801 ccacgatgga gatttgattg tggacgagtt gatgcgcatt atacaggtga aaaaatgagt
    19861 ttcacagtag caataaaaga agaaatcctg ggccaacacc atctgagctg gcatgaatta
    19921 tctgccatta tcaaaatgtc tggtagcatc ggtctctcga cttcgggctt gactttgtca
    19981 gttgtgacag aaaatgccaa actggcccgt cacctctatg agtcctttct ccatttctat
    20041 gaaatcaaat ctgaaattcg tcaccaccaa cggagcaatc ttcgcaagaa tcgcgtctat
    20101 acagttttta cagatgaaaa ggtgcaggat ttgttaagtg atttgcactt ggcagactct
    20161 ttctttggcc tggaaacagg tattgatgag gcgattttat cggatgagga agcaggtcgt
    20221 gcctatctct gtggcgcttt cttggcaaat gggagcattc gtgaccctga gtcaggcaag
    20281 taccagttgg aaatcagttc cgtttatctg gaccacgcgc aaggaattgc ctcccttctc
    20341 caacagtttt tactggatgc caaggtgctt gagcgcaaga agggggctgt gacctatctc
    20401 cagcgagcag aagacattat ggacttcttg atagtaatcg gagccatgca ggcacgtgat
    20461 gattttgaga gggttaagat tttgcgagaa acccgtaacg acctcaatcg ggctaataat
    20521 gccgagacag ctaatatcgc tcggacagtt tctgccagca tgaagaccat taacaatatc
    20581 agtaaaatca aagatatcat gggcttagaa aatttgccag tagatttgca ggaagtggcg
    20641 caactgcgga ttcagcaccc agactactct atccagcagt tagcagatag cctcagcacc
    20701 cctctgacca aaagtggtgt caatcacaga ctcagaaaaa tcaataagat agcggatgaa
    20761 ttataacgat ataaagcaac cccttgaatt atcaatatct tcaaggggtt ttgttgtgtt
    20821 atgaaatcaa aaaggggcaa ccaaggggca gaattaaaaa atagtatcta atttattgac
    20881 cagtttatcc tccatatctt cagtagtatg agaatagatt tccaaagtca tttttgcatt
    20941 tgagtgccca actcgatcca ttattgattt tattgggagg ccagactctg ctaaaaacga
    21001 aatatgagaa tgcctaaaaa tatggctaga taagtttttt tctattttgg cctgttttcc
    21061 atattttttt aatatctgta tgaagcaagc tattgttgta ggttgattcc atttttcaaa
    21121 acagaaaata taatcatcgc ttgacaatgg ctggaaacgt tcgctaagtc gtactatttg
    21181 tctttgaata gcttctatga cattctctga tactttgatt gtccgtattg aatttgtagt
    21241 ctttggtagc gtcttgattt tgtttactga atcaaaatta cctgtgatct caattttgtt
    21301 gttttcgaag tctatattct tcagttgtaa ggcagttaac tcaccatatc tcataccagt
    21361 taatgtcagc acaagaacca tatcagcgta cttttggtga tattctcgac gattaaggac
    21421 atcgacaagt gcttttattt cttgcatggt gagaaagttg ttacgctttt tttccagttc
    21481 ttctaaagtc tttggttttt gaggaatcgt agtataatcg acctcgttgt tttcaatgta
    21541 agagtattga acagcgtaat taaagatacc tctgagccta tgccgtactt ttttagctgt
    21601 aatatatccg ttgctttcaa taattttttc aatagcctct tgaagaaaac gcctgtcaag
    21661 attagcaagt atggtatcgg atggtatgac ttccttcatc ttcttatcaa ctgatttaca
    21721 attatgtttt gttgattcct ttactgtttg cgcccatgat ttataaaaaa ggttatagat
    21781 ttcttcaaat gtaatgcttt ctacttgttt tgtgctaagt tttttattta tcttctcttg
    21841 caacaagata gcagcttgat ttcttgcctg gggagttttc ttctccatgg tcactgaaac
    21901 tttttttaat ttctcggtat acgggtcttt gtatcgttca aagaatttgt attttccgtt
    21961 gggaagttct tccatccaca ttgcgtttac ctcacttttt tgttaaaatg ggtataagaa
    22021 aaagagcttt ttaatgcttt ttttcttacc actagcctca cgctctcggt ctgcaaactt
    22081 ctgagcgtgg ggcttttttg agttgtttcc aaaatggaaa cagttggttt ttattctaga
    22141 cctgaactaa ctttagaagt caacaagaaa gaaccgtcgt cttgttttga aaacgaaaga
    22201 ataacgctct tgtatttgct accagtagaa gtatatgata ctgtcttact gtcgtggtca
    22261 tttactgaac tagttgttac attgttaggt tctccgtgaa cgctagcaac gtcatcgtag
    22321 ttagttccac cagctccata gttgataata tcaccaactt gaagcgcatc aaactgttct
    22381 tttgtccagt taaatttagc atcttcttct ttttgagatg attcgataga agaacttaca
    22441 gagctaacag tctcttcaac gtttttacct agttctttca atgatttagc gtacattgct
    22501 tgagttacta atacaatagc aatagatacg actgctagaa ccgtcccaat aatagctagt
    22561 gtttttggtc tttttcgatt tactgcaaaa ccaattaaac cgaagataag agctaaaata
    22621 gccaaaatga atgaaaaatt attgatgata ggcatccatg agccaagtag agccagcgct
    22681 ccaaaaataa tagctaaaat acctaaaact ttgcgttctt gtttcataat gaaacctctc
    22741 tatcagcttt tagtgtggat cagttgttgc acatattttt aatttactaa tgataaatac
    22801 tcttctttaa ccatgatttc atttgtcatg gtttttagat tgtagtaaga catgaatttg
    22861 aggtaatcaa actctgtggg gtcgtctaag ctttctagcg cgtcttttac gagatgatgg
    22921 atcatatttc tatcagcttc gttttcacag cgtagtcgag cgttctggta ctctgagagt
    22981 gtatggtctt tgtgtccaag ttcgtgtagg gcgacttgga tttgttgttc aggagtcaag
    23041 ttgtggtcaa tagcgagtac gtttgtgtct ggattgtaga aaccgctact gtgccagttt
    23101 gaaccgtcga agagacaaag ttctacttga tattcttcgc agagtttagc gagtgtcata
    23161 gttctccttt taattagcca ctcgataata acttttaata gctggatagc tttttagttg
    23221 gctttcttga cgtttctttt tttgttcaaa ttgatgaatg gattcattac tgagccgtag
    23281 catgtaatca tattcactgt tattttcttt tggtcgttta acttggacgt gattcatttt
    23341 agattctccg tttttaattc tataattcct ttgtgatttc tatttctatc aaaaccaaat
    23401 tgtcccatcc agtatgtttc attgtgagcc atgtgggaat atataggacg agttttttca
    23461 atatgatctt tatcgcctat ttgatagatg tctaagcagg tacttgcttt ttctttaata
    23521 tcttttagat atttctctat gtctggagaa tgtttaaaaa atagtaagac atctatgtct
    23581 tttgggtttt ctttctgggt gcaaaagctt ccgtctagcc atatacgcgt aatgatattg
    23641 ctatctagat tttttaagaa agttgagaga gcttggaaat ttctagttct ggtagtggag
    23701 tttgggaagt tatctactag agttgattgt atttgtgcta gtgagatatt tgttagtatt
    23761 cctccattta ggttaccttg atcattgaag tggagtttag cgagtgtcat agttctcctt
    23821 tgttatttat aaacctctct gcggtgggcg atgtctacgg ctaagacgac tagtttatcg
    23881 tcttggatat cacagatgat gcgctaatcg ccaactcggt atcggcagta acctgatagg
    23941 tttcctttta gtagtttagc gtgttgatag gggttgcttg tgttgtctac gttttttgtc
    24001 atccacgaga tgatttttcg tctagttgct ccatcgagtt ttttgagttg tttttgtgct
    24061 ttgctttcat agacgagtcg gtacattagg cgatgtcctc tctggtcatt ccaagacttt
    24121 ccaagagttc atctgttgta tatgtttttg gattagggtc ggctaaatac tccatatagg
    24181 cttggtcggc tgctcgtgcg tcttcgatat cttccatgag tgccatgaag tcgtcaaaat
    24241 ccatggtcgt tgtgttgata ccgtgtttgt ttaggtagtc cgtgatgtag gaattttttt
    24301 ctgtgaagtt gatagtgata gtcattagcg ttctcctttg cttttgaagt gggcggatag
    24361 gacggatgtg atgaagtcga tatcatcttc atttagtggt ttcccgtcaa ataacatggt
    24421 gttggctgct gctttgcgta agtctatgat ttgtccgttt acttgggcaa attcatcact
    24481 cccagcaata gcagggttat ctgtacgacc tagaagataa tcagtggaca cattgaagta
    24541 gtcagctatt tctgaaattc gttcagtaga tggttttgaa ctttttaaat tataaatggt
    24601 atttctactg taaccaagtt tttcttccaa tgaatttatt gaaagtcctt gctttttggc
    24661 aagttcttta attctgtcaa atgtctgaaa cattgatttt tcaacctttc tgagaacatg
    24721 acaaaaaata tttaatattt ctcattaaaa cacttgacaa agttaatgcg aagtattaaa
    24781 atagtttttg taagttaatg agttagtaaa aaacgaagtt aaaacttatc taaaaataaa
    24841 tagctttggc gagcaagaaa attgatagat ataaggtttt atcaaggttt ttaattatgc
    24901 tttcatttta atactataca ttaattttgt caagcatttt ataaaacaat ttactaactt
    24961 tttttcttac ttttaaagaa aggagggagg cagatgccaa acatggatgg tggacgtcaa
    25021 aaaatcagag attatctgaa agagcacaac ttgacgatgg cgacgctagc agtacagtat
    25081 agcatggctc gtcaggatgt gacgaatatc ctgaatggaa agctaaaaaa tccacaagcg
    25141 aatcagttca tcgctcgtgt gattgaagat tttaaaattc ggtaaaaata ttggtttaag
    25201 taggaggaaa gatggaagaa gacatcagag ttcacatgcc ttacgaggta tttaaaaacc
    25261 tgcttgttag agcaggcaga ataaagcgtg aagaaggcaa gcagataact tggacaaata
    25321 ataccgctcc gtttacaaaa gagcaacgga gggaaataga tgaactctac gagcagttcg
    25381 cagaagattg aatgtggagt ttgtcattga tatgtttgtt agcaatcaat aaacattcat
    25441 taagcctatc aaaaatatat ctgggttctt cgattgtgtc tgggtcatag gactgttctt
    25501 caaattgcac atcccaaata taaagcccat cggggtgggg atatccagct tgataacgta
    25561 gcacatttct aaaatagatg aatttttttt gctcttcatc gctatctaaa aatagatagg
    25621 tcttataaaa gatatcatcg aagtttgtga tgatatctaa atcaatcgga ggagcatcgt
    25681 caagtcttga ttctacgtat gagacggttt taccactaat cgatgcaaaa ttttgaaaag
    25741 ttgaaatata taaatctcta tcctgactta gttgggtatt taagaaatca accttctttt
    25801 cttcgagttt atttttattt tcaatctttt tttgctggta agcaaaaccg tgaataatca
    25861 aatttgttaa aacagttgca ccaacagaaa tcaatgttgt tgtaaatact tcagacatac
    25921 aaatacctca gataatattt ttaaatcatt atatcacaaa cagaaaggag taggatggaa
    25981 gaatttattg atgctcttga aaaagaaaaa gaccaccttg aaaaaatcat tgaggtagtc
    26041 agctctggtg gtaaatttct gagattgccg tatcaaaaaa gtcacgctcg attagtgaga
    26101 atctgaaatt gatttctcaa aatcttgata gactgagctg tttatataac caaagaggag
    26161 aaagaatgac agacagagaa ctatttaagt taccagaaga ttatgtagaa tctactggac
    26221 ttgacaagat tacatttgaa gtaccttttg aattgtttac gaaaattcta aaagggtacg
    26281 gacataagtt agcgtgggag gatttccgac aaataaaaat ccacccaagc actagaacaa
    26341 aaaagacggt tggacagtgt cagtttttgt ttagtatttg gatgaatgat catttgaagc
    26401 cagcgattaa accttcaaaa gagttgcaga aagaacctgt gcgtaagaca aagaaacaga
    26461 aacgtcttca taagttagca caaaatcttc ttcatcgcat gaagggttga aatcgccaat
    26521 gtatgcacct tgctctgttt tgcagattag aagagtacca tcttcgtttg taactgcatc
    26581 tagataaggt cccaaatcag acttagtcat aagttatcct cctttctgct tatattatag
    26641 cagaaataga ggttagaaat agaaaggagt aggaagatga gaccaaaacg atatccgtat
    26701 agtgggaaaa aagagtccac ctttgtaaag gcagaccctg agttagttga aaaactttta
    26761 agaaacacta gttttcttga gtgtttacaa aaaaagccta tcaattttca gatagactca
    26821 gaagaattta agcgtcttag ctataaagcc attcatgata cttctcaagt aactcaatag
    26881 gaggaaggaa taaaatgatt caccattata taactcacta tgccagcaat gggaaagatt
    26941 acgccgaagc atggattcaa attgattttt tgggaatgtg cttttgtgta tggaaaaagc
    27001 gtacaaccat tgaacgattg tacgcaaacg aagattagac ttttttccaa ccgttgcctt
    27061 tagcagatgt cggagggagc cgatcacctt ttccgatagt tgcggtatga ccattagtaa
    27121 cttttccgcc acgaggtcct acctctacat agcgaccagg tttctgatta tctgttccag
    27181 gttttattgg agtatttgcc atactatctc ctcctttcta ttggaatttt gactaaaacg
    27241 gtgagaggtc ctagtcaaga gtattatagc aatttaggag gatattacat cagtcttgag
    27301 gctgatatag gaggttgaat ggaagataaa attatcgaac ttgctgatta cttcatcagc
    27361 gaatctacaa cgtacagaga agctaaaata gcgtgtgaga agctattgaa acaagtcagc
    27421 catgagatag aactcagggc gatggaaagt aggacagtat gaaagaagca gtaaaggaat
    27481 ttctaaaatt caggagccga tttacaaaaa tagaatggtt tgaaattaac caagctatcg
    27541 aagctcgttt aaatcaaaaa gccgaccagt tgaaactgga cgacttagat ttagaaatca
    27601 tttctagcag actagaaaaa gttatctaga aacgatttga atgaacattg gatggatacg
    27661 atagtcagcg ccacgatagt gaatgtagat ataatcctga tggtacatcg agtttgcttc
    27721 aggtttagaa attggtgagt agagttctgc attttcttcc caccaaatgt aaggattagc
    27781 catatttggt cccattacac aatcgtcgtc ggctgatagg ttcacccaat ttccgcaaag
    27841 acatgcgtga atttcagtca taatattacc tcctttctgg tttcattata gcagaaaagg
    27901 agatagcaaa aaagcacctg acggcaatca ggcgcatgac aaaattattc aagaaaatta
    27961 taacacgaaa ggagcaaaaa tggaagtagt tgaaattgta agaattaaag atgtgatcat
    28021 tgaaaaagtc tctgctaatg atgaagagtt aaaacgtatc tttggatgtt caaaacgaca
    28081 agcaggagag cgaagaagag aaatgcaaaa actccctagt cagcaaaaac atcttttgga
    28141 tagtggacaa cttgtaacga ttaaaggttt ctatgaatac ttgcaatatc gtggaactaa
    28201 agcttggaaa aaagaaatgg aaacaagaaa gaaaatgagg tcagcaggat gaacctacta
    28261 tcaagaatca aaaactattt ttcggaagag gtcaaagaaa ctaatctcga ctggaaagag
    28321 gtcgctttag acctcaatca atcactaatt gaaacacagg aaaaacttca agaagcgaat
    28381 caagaaatcg cagacttgaa gaaaatcgta gcaatctaca aagaaaagga gaaagaaaaa
    28441 tgatggaata catttacctg gtaataatcg taggaattgg actatggtcg ctagtaaata
    28501 aactagatga ccacgctgaa atgaaacaaa aagagcgcca gctgatggca aacaatgtcg
    28561 cacggatgaa tctgagaaat tcagataagc aatttactta tgatgtagaa ccgcctgaag
    28621 ggttgaaata aggaggagaa acatgactca agcggaacaa attagggaat attatagaga
    28681 gcaccctgct gcctcatgtg atgaagtggc tgaggttgtc ggtacaacaa aaagcaacgt
    28741 aagtgcaaac ctggccaaag acatcaaggc aggcagatgc gttcgcttgg aagacaagtc
    28801 atacgactac tccccttact ttaatcacac acaagcgctc actgagttgg ttgattggaa
    28861 gaatgatacc agacgtgagt gggtggatat gctgacaaga gcagcagaaa aagaaacgga
    28921 tagcaatgtt atgcgtttgt taatcaaaga agcaaataaa ttgatgaaag aggtgacgaa
    28981 gtaaatggtt cgaaataaat tgacagattt aacaaatact ttgtttgctc aattggaaac
    29041 cttggacgat agggatctta ctgcagatga attaaagacg gaactccaac gttcaaaaca
    29101 gatggtcgca atctcaggtc aaatcttaca agcaggtcaa ttggcgctag atgctgaaaa
    29161 attcaaagac aaggtaggtg aagtcaatgc cccgatcgct ttgctggaag gatgagtata
    29221 cagagtacat gcatgagata tgccctggcc gattaactcc tgaagtaacc aggttactaa
    29281 atgagaaatt tggtacgacc tataccaaga ctcaaatagg agaagtacgc agacgtttag
    29341 ggttacctgt tggaaaagta tatcaaggta aattgttgac aaaagaacaa catgattacc
    29401 ttgtgtcaat ccaaaaaaat aagatttctc gcgatgtcgc aaatgaaatg aacctaaaat
    29461 ttggattatc actgactgag aaacagatta agagttatcg aagaaataat aatctacata
    29521 gtggtttgac aggaagattc gagaaaggtc agactcctca caataagggg aagaagtacc
    29581 ccaatatgcc aaaaaacagc gggcagttca aaaaaggtaa tcgacctccg aattatgtac
    29641 ctgtcggtac tatcaactac acaacaaacg gttatccaaa agaaaagatt ggagaaccta
    29701 atcaatgggt tttgaaacac cgcaaggttt gggaggacca tcacgggctg ataccaaaag
    29761 ggtactcaat cgtttttctg gacggtgata aaacaaacta tgatatttca aatctggcat
    29821 gtttatctaa gaacgaaatt gctagaatga atcaaaatca tttattcacg tccaacgctg
    29881 atttgactaa aacaggtatt ggactaacaa aacttacaaa taaaatcaga gaggtagaaa
    29941 aaaatggcta gtttatacga actaacaggt cagttcctga caatttacca attggatatc
    30001 gatgacgaaa caaaaacgga cacacttgag gccatcgatt ggcaagaaca atttgaacag
    30061 aaagcagaag gatatgccca tgttatcaag aatctagaag ccgacgtggc catgtacaaa
    30121 gctgaggaag agagcttcaa agccaagaaa caggtggcac agaaaaagct ggattatgta
    30181 aaggataaca ttatggcagc tatgaatatc acggggcaaa ccgaagttaa gagtggtgcc
    30241 ctgattataa aaattgctaa gaatccagaa tcagtcaagg tcaacgaaga cgaccttccg
    30301 aaaaaatatt ttacaaaaaa agtgacgctt gcgccggaca aaaaaacact caaagagttg
    30361 cttaaatctg gcaagaaagt caaaggtgcg aaacttgtcc ggacagaaaa gttggtgatt
    30421 aagtaatgga attgatgaat aaaacacgag taacagattc actagcagtt gtgattggac
    30481 tagaatcgat tgaagtactt gttactgaag gttttctatt tgatgttgcg attcgttttg
    30541 taaaagtaga cgaaacaaat cttgatcaag gaaatgaaaa gccagtattc actccggaat
    30601 gcaagctggt cacagttgct aaatacaagg aaaaacctat ctttgaatcg gaggaagata
    30661 ttcgaaaatt tgagaagcaa gcaaaagaag ttaaatcgct atttgccttt gcaaaggtaa
    30721 ataaacaaaa ttggtttaac actgcccttt atccaggagt gctgactgag aaagttggtg
    30781 tttgatgaaa attttagcta ttgatccaag cagtaataaa attgaaacca gcacaacagg
    30841 agttgtcttg ttggataatg caagattagt tgatagctgg gttgtctctt atggtatgag
    30901 aggtttcgct gattggtttc acgaaatcgg aacaaatctt gaattcgatg tagttattgt
    30961 tgaagaattt aaggcgaggg ataacgacaa gtcgaaagat aatagcgtgg cagaaaccat
    31021 cgcctatatc caactttgct atccaggtgc cattcttcaa ttcaatgcag gttacaagtc
    31081 ggatattcca aacgatcttt tgaaaatctt agacctttgg aaatttgaaa aaagtcatca
    31141 tcaagatatt cgagcagcag caagacttgg attattttgg gcaatgagaa atgatattga
    31201 agaagtggtt catgatatcg gaaaggtggt gagtgagtat cacaataacg ctaagaaagt
    31261 ggcaagctga agcgattaaa agaagtgaac atttatctaa tggaatcttt ttagaggctc
    31321 ttgggggcag aggcaaaact atctgtgcac ttgctattgc aaaacataaa aaagctaaaa
    31381 aaatcatcat cacaaacaat cgactagcta ttctgaatgg ttggatagat gcagtcaagt
    31441 ttatgaattt tgataaaggt gttgagatta tcattcagac agatagatat cttcaaaatc
    31501 aagtcaaaaa ggggcataaa ttagattgtg atgtgctgat agtagacgaa tggcagaata
    31561 tgtcttctga caaacaagtg gccttatatc gcaaaataaa gcgaaaatac acgataggtc
    31621 tttcagcgac accaattcgg aaaaaaggac aaaatttcta tccgcttgaa aaaacggtat
    31681 ttggttgggc aaccccaaat aataaatttg actggcaaaa gactcatggg aaaatggtct
    31741 atgatccatt tagctattca aaagagaagt gggaagattt tcaaaattat gaaagttata
    31801 tctcgagctt gcctaatttc ttccgctggg aagagattga aggaattgag aatgcagttg
    31861 agaataacgg ttttgagatt aagttttacc gaaagagagt cgcctctggc aatccagaaa
    31921 aacttgcaga atttagaaaa ctaaatcttg taacagtgga cggcaaaact gcaatggcca
    31981 agcaatcgtt tggaagaaag acctttgaac gctaccttaa tcaaacaggc gtagcagtcg
    32041 attttccaaa attaaagcca gtaaatgcgg atacgccatt gatgttacaa cttgacggtt
    32101 taatcgaacg agcaccacac gatatgttga ttgtcagtaa atctaagcag attgtcaacg
    32161 tcattagcga gcgccatcct gaaattggaa tctggacggg cgatattcaa gaaggacttt
    32221 ataagaaatc cgtggttgct actagtcaag tgttaggtgt cggagtagac ggcttgcaac
    32281 acaaatacca aactattgtc gtattggatc cagtagaaga aggttctgga gaatatgatg
    32341 attatcgaca attgctctgg cgcataacag gaagtcgtca gcagcatgat gtaaatgtaa
    32401 ttgaatttta ttataaagaa agttaaaaaa agaggaaaac aaaatgaata aaacaactga
    32461 aatgatcgta tttcgtagcc gtaaaactgg agaatttctt aattcttaca aggacagaag
    32521 ttctttagca tttgcagctg acttttgcag cttggaatat tgtttgaagc ttcctcgtaa
    32581 aaaatacgaa gacaacaaaa agacttacaa ggctcttgct gcagcttttg actgtgaaat
    32641 tgtcgcagtt gaagcggaat acaaattgac ctatccgaat ggatcagaag ttgaacctat
    32701 caagcgtgac cgttcatcaa ttgaggacat gattaaggat attattggag gggttctcta
    32761 atggcattta cacttccagc aaataaacca caagttccta aagatacccc agaaattttt
    32821 tcatctacgg cgaaaccatg agcggaaagt cttatcttgc aaatgaattc ccaaatccaa
    32881 tcgttttgaa cacagacggg aatgcagaag ctaacactgt tccaagcatt cagctgatca
    32941 atgaaaaaga tgacaaggga cgaattacca attcagtaat taagcagctt ggagatatct
    33001 tgcttgctct ccagacacag aagcactctt atgaaacagt cgttattgat gtaattgacg
    33061 atgttattga aatgattaag attgcagttt gtgatgaatt aaccccagtt ggtaaacctc
    33121 gcttgaaatc cttgtcggaa attccatacg gcaaaggata cgacttcttt aaccaagcta
    33181 tcacagaatt agtcattgac ctcaaagcat tgccaatgaa tgttatttac atcagccgtc
    33241 aggtatctga atatgatgac aatggcaatg ccaccaaaga caagccaagc ttgaaagata
    33301 agtatgtcaa tcttatcaat ggaaactctg atttgatgat ccacactgaa aaactcggca
    33361 acaactacaa ccgtgaggtt gaccgcaagc gtaagaccta ttatgcggac caggttgatg
    33421 acaaggccat cttgaaaatc ttggcaacta tccgtggggc tgttgagcct gcaaagggca
    33481 agctagctcc taaaaaagaa gcagctaaga caactaaacc agctaagatc gaaaaaacaa
    33541 aagaggcacc taagaaagaa gttgactctg atgatgaact attttaagaa ataaaggaga
    33601 atacacatga gcttactaga tatcgcaaaa tcaatcaaaa aagagggctt tgacccacgc
    33661 aaagacagcg ccaacggtcc tgcaccaatc ccagctggta cttatccagt agtcctgaag
    33721 aaagcaacct tcaacgtatc ggacaaaggc tgggaaagcc ttggttatca atttgaaatc
    33781 cgtggcggtg attacagtgg acgctctgaa tttgcaacat ttggcacact gactgaatgg
    33841 aacggtaaga accttgactg ggcagttgaa cgcactatga aattctttat caaagccttg
    33901 gtccttgctg gcgacagtat gcaaggaaat gaagaagacg gtaaagcctt ggaagaggct
    33961 ctacaacgta aggcagttgg ctcttactac aaccttgtta tctctgtgac taaggggaaa
    34021 gatggccgtg agttccgaaa ctatgacctt gaagaagaag aagcacaacc gctgactgaa
    34081 gctgatatcg atgaagatga cctccctttc taaaaaatag caagttttgg gtcattgatg
    34141 aaactgatga aagattagga ccattcaata catttgaaga ggcttatcaa tcgttgttat
    34201 tttatttaaa aatgactgaa gatgaatatc agtcaaacta tacggcccag gaacttgttt
    34261 atatttacaa agaggagaaa aaaccatgcc gtcgatgaaa gaatacgcat tacagtacca
    34321 aaagttaggg ttctcagtca ttccaatcaa tcctaaaaac aagatgcctt taatcgaatt
    34381 tgctgataaa ccagccatga ctgcaagtga aatcgaacga ttttgggatg gatacccaaa
    34441 tgcgaatatt gctttaagga caactaactt ctttgtcatt gatatcgata agcatggcaa
    34501 agagaatggc tttgagtcgt taaaaaaatg ggaacattta aatttaattg aaccaactct
    34561 tcaagccaaa actgctagtg gtggaaagca tctgttatat ttcaaaagag atgatgaacc
    34621 aattactcag atgattaaat tcttgcctgg tgttgatatc aaagcgcacg agaataacta
    34681 tatcatagta gcaccttcag caacagagaa tggccagtat gagtgggatt tggagaaatc
    34741 agcggaaggt gggacaatcg taactccttc ccgtgatcta atccgagcaa ttaagaagca
    34801 gtatggtaaa actcatggct atagatacga tggcaaagat ggtcttaggg atttagcgag
    34861 gcgttcacaa accagagacc gaacacagac tacagatctc tttgaaacca tcgcccttgg
    34921 ttttggtgat gaaggtggac gaaatgacaa actagcaaaa ttcgtaggtg gtctcttata
    34981 tcgtgcggtc gacgatggtg tagttgttca acttgcaaga ttagcaaatg caaatagtcc
    35041 aaaccctttg cctgaaaagg aaatgatgcg tactattgaa agtatgatta aaaaagatag
    35101 gaggtgattg tgattggtaa tgtagtaagt attgactcac aacctaagat gataacgact
    35161 gccaagggag acatcaaggc caacagtcca agtaatgtgt tgatgtcttt caaagctgat
    35221 gatcagttga gtatttacct aaagcacaac gatttttccc aagagcatga actccttaaa
    35281 gatatcaaga tcggcaacac tctttttaaa aaaggtgagc tcccttctaa ctttgattca
    35341 gtcgtaaaag tttactttga aagtgtgtta ggtgttgctt tctcaaacca agcgatgctt
    35401 gatggcatgg agactttctt ttcagaaaga tcatacaatc cagttattga gtatatggag
    35461 agagcaactg aaaagtggga cggcagaaac cggattgacc gcatgcttca agtatatctc
    35521 ggcgctgaag atatcccttt agtttctaaa atcgctcaaa tgtggctagt tggtgcagtt
    35581 gctaaagttt atgatccata cgttaagttt gactatgttc tggacctggt cggtggacaa
    35641 ggagttggga aaacgtccct ccttcaaaaa ttgggtggcg aatggtatac ggatgccgta
    35701 acagatttct ctaataaaga taattacgac attatgttaa agagtctaat cgtcaacgat
    35761 gatgaaatgg tggccagtaa tcggatgagc tttgcagaaa ctaaggcctt tatttctaaa
    35821 actagcctac gttatcgtaa accatacatg aaacgaacag aagaatttgc caagaacttc
    35881 atcttagcca ggactactaa tcaaaaagaa tacctcaagg acaaaaccgg tgaacgtcgt
    35941 tttctaccag ttatggcaga tagtaaacgg caaaaaaaac atccaatgga aatcgagcca
    36001 gagacaattg aacaaatctg gggcgaagcc gttacaatct atcgtgctgg tgctgatttg
    36061 atgtttgatg aaaatacaga ggatgaactg aatatctacc gtgaacagtt catgtatcgt
    36121 gatgaagttg aattacaagt gcttgaatat cttgatatgc ccgtccctga aaattggcaa
    36181 aactggtcta ttcagcaaca acatcaatac acaagtaaat atttcgataa tagtagcgac
    36241 tttgatcctg gaagcaaaaa actagataag gtctcaactc gtgaaatgat gtacaactta
    36301 tttatgagaa attcgaatga caggaagctg tcaacgaaga ttaacatgat catggataat
    36361 catcctgatt ggaaaaaaag tgttttccgg gcaggaggta aaagtacaaa agggttcgta
    36421 agagtgaaag attcggaaaa aaactaatcg gtagcaatta aaaaattatc ggtagtcatc
    36481 ggtagcagtt gagggggaga tcggtagcat tctaccgata aaataggaca tcggtagcac
    36541 atcggtagca gtctaacccc ttgatattac tgacttttat ttaatattta tatataatgc
    36601 tactcttcta tctatatttt taaaaaaagt atataaaata atagtaataa taaagaaagc
    36661 ctataaaata gggattcttg aaaaaaactt tttacttttt agaatttatc ggtagcacgg
    36721 tagcagttta gaaaaaagag gtaaaaatgt catacacagt aacattattt tttgacaaca
    36781 tggtagacga aactcacttt tttaagaaag agagtgatgc tgccaaatgc aaggcgcagt
    36841 tagaaagcaa gtatcgaggg aatcgaatgt ataaagttaa gcaggagaaa ttggaagaat
    36901 gaataagcag gaattgattg agaaatataa agagctggag aatagttcat ttgatattgc
    36961 agcgattgta gtttgtcagc taattttaaa agacttggaa cagctagatg aaccaaaacc
    37021 ggtcaaagtt cagcagtttg tggcggattt tatcgcagaa cagaaaaaac tgggtcatac
    37081 actgtcctac tcaatagacg caagcatgtc tgatatagtt gcagaatggt attgggataa
    37141 ttccgaactc ttcgcactag cttggatttt cggctacgag gtcgaggaag agaagcggta
    37201 tacagtagtg acgaaagcaa caaaacaacc gctatattat aatgctatgg ataagaaact
    37261 attcttctct atgggcggac tagctacaaa atttactcgc aaacaactca aagaagcgga
    37321 cttaggctgg gttttcgatt gtgaaggaat tgagattgag gaggtggagt gatggaagat
    37381 gagcaaaata ttttagagac acaattgatt ttaggtaagc aagttttaga aattgtattg
    37441 gatttgctaa aagacgattc aaaaataggg gtagttctac ctttaaacat aaatgaccgt
    37501 gaatttacaa ttactgtaga aaaggaggtc acagatcgtg actaaggggt gtttgtggtt
    37561 atgaaggacg tgtatgacaa ggtgaaagtc ggggatgagg tgatgttgtg aaattcttga
    37621 atttattcgc aggaattggc ggttttcgtt taggaatgga gtctgccggg catgaatgta
    37681 taggattttg tgaaatagac aaattcgcta gagctagtta taaagctata cacgatacga
    37741 aaggagaaat tgaattacat gacatcacaa cagtatcaga tgacactatt cgaggaatcg
    37801 gaagtgtgga cattatctgt ggaggatttc cgtgccaagc tttctcaatt gcaggaaaca
    37861 gacgaggttt tgaagataca cgaggaactt tgttctttga aattgctagg ttcgcatcta
    37921 ttctcagacc taaatatcta ttccttgaga atgttaaagg attgctcaat cacgaaaatg
    37981 gagttacatt cgagaccatt atctcaacct tggatgaact ggggtacaac gtggaatggc
    38041 aagtgcttaa cagcaagaat ttcggagtcc cccaaaatcg ggaacgagtg tttattatcg
    38101 gacatcttag aagagaacgt accagaagaa tttttcctct cagcggaaaa aatcagtcaa
    38161 ctagtaacca atcagtcatg aaaattggga atataaaccc atctggcaac ggaatgaatg
    38221 gggaagtcta tcaagctgat ggtctagctc ccacgctaac aacaaacaag ggagaggggc
    38281 aaaagatagc tataaatagc tatcacgaaa acaatcattt atcagatggc tttcgaatca
    38341 gaaagctaac acctaaagaa tgctggaggt tacaaggttt tcctgattgg acttttgata
    38401 aggcgcagga ggtcaactct aacagtcaat tatataaaca agcaggaaat agcgtgacag
    38461 ttaatgtcat agcagcaata gcaaaggagt tatcatgaac gcactagaaa aagtcgaaca
    38521 atggtttatc gaccgtgaaa tcaaagatcg aaaaggtcgt tggattgatg gtgctttcgt
    38581 caaagaggag gatttggtat gataccgaaa tttagagtgt gggtaaaaat aggaaaacgt
    38641 atggtttttt cagatgacat tcttgctatt gactacgaaa acaaagaaat agtgacacaa
    38701 caagtctatt tcgagagtgg tctagcagtt gaaagagata tctattgtta tgattttgac
    38761 gatatcgaac tcatgcaatc aacaggactt aaggacaaga acgggaaaga ggtctttgtc
    38821 ggagatatta taaaatgtac aagaggatgt ctccatgaag tatatttaga aaaagaatac
    38881 ggtggcacat tcataggcgg aatgccttcc atatatctaa agggattgct aaatgggtat
    38941 gcgtggactg aagacgagga aatcatcgac aatgtctacg aaaaccctga acttttggag
    39001 gtaactcatg aataaacgtc aacgcaaaaa gaaaattttg aacggtctga acaaagaaga
    39061 aagataccac aggacgcatt gtcctgtctg cgatagcgaa gctggtttat tcgacagata
    39121 ttttaatacg tacggtttct gctctgaata ttgtggttat gaatactatg gaatttcaag
    39181 attataaaat aaaggattga ggttaaaatg acattatttg atgaaatgca gcaattaagc
    39241 tcagaaagcc acgcaaaatg gttcgagcga tattttgaga aatataacct agaacaaaaa
    39301 ctaaaaactt ctgctcaaaa aggttataca ggttatttaa tcaatgtttg gtcagttaga
    39361 gacgaatatc tcaggaatcg attaggagat gaaagaacgt tggaagcgtt aagagaatta
    39421 ttaggagctg gctttactgt caaatataag ctttatctat ctaaaaatat tttcactgga
    39481 caagatttcg tttctaacaa gaaaattcac attacttggt aaaacaaaaa agccaagaca
    39541 ctctctgtct cagcaataat ctcaataata ttattatatc acaaaggaga cagagagtga
    39601 acaaggctaa agaactattg aaagagttgc agaatctgga catggacatt caaagccgta
    39661 tagatgaaat taacgagctt gaggcaggtt tgctctcaag tcctaagtgg tcagatgtca
    39721 aagttcaagg tggtcaagct agaaaagttg atgatgtcta tactcagctt gtcgtgatga
    39781 aagaggctat agaacaggat actaaagagg ttatcaacag aaagctccaa ctaggtagga
    39841 tgatcaatag gcttaaaaat ccaaaacata gaactatttt gagaatgact tacatcaata
    39901 agatgtacgt tgatgacatc tgtgacagca tgaggggcat aagttctcct acttactatc
    39961 gtttgaagaa acaggcagta aaggagcttg atattattct ttcagaattg atagtaaatg
    40021 atagtaactg tacaggcatg aagtctaaaa tctgttaaaa tggtagtatc aagaattgaa
    40081 aagagaggtc tcagaattgg tagatggtta cctgtaatgt cagggggctg taatggcctt
    40141 ggaggttcaa accctcccct ctcctttgag tgtttgtgtc ccagaatggg gtaggcaaca
    40201 ggcttagcat tcatatatca ctcattaact tacaaatggt tgcggagcga ctggaccttg
    40261 catgattgcg tagctaatta tattccggat aagttataag ctagagggtt tgattccctc
    40321 agaggtttta aatgactaca aaaaataaaa aaagaagtca aaatttaata cgcacgcaag
    40381 gttgtagtcg ccttgcactt ttagggctta gcctagataa tctgtggtaa ctcaggaaaa
    40441 ggatgttttt aaatctatca aacatcctgc cagcaatggt caatctaagc aatgtaatct
    40501 taactatttc agttttggaa taggtgggcg aagttaaagc agaaagattc caacggcaag
    40561 gtgctgagga aatgcaaacg tggcagtttg gctgtgaaac gagtctataa gaggaaagag
    40621 gtatttggtt cgaggtgcaa caagagctta ataccatatc ttacaaaaat tgggcgcctc
    40681 ccaaaagtat gtaaggtgag ttgattgtcc gcaaaacaat cgataacaag caggcgctgt
    40741 gcattttgtt cttcaaaaga ggatgaaaca catggcgatg cgtgtctgtg atagatgaaa
    40801 gatgattttt atattttaag gctattcaag atagaaaaaa attcgaaaaa agcaaaagtc
    40861 atcgcccgtc gcaaacgaaa gtgtacttcg gcaattagat tgcctgctca agtctcgcaa
    40921 ggataagagt aaagtcaaag agtaaagcag cttagacttt tagcggggtc ttcgttaatt
    40981 gaaaaatggc ttagtagttt gtgatgtaag aagtgattgg tctaaccaat cgtgcatgag
    41041 tgatacaagt aggaatattt gtggacaaga taataaacta taagttatca aaagtcactc
    41101 gtttaaagca gtagtctcat gctagttaat ggatacatgg tagacggatt aagtcctgtt
    41161 tagggaattg aaacgtaggc aggttcgaat cctgtcgttc caattgcgat tttaattcgc
    41221 agagagaggt cttgaaaagg tcgcacatcg tgtggctttt ttgattgttt gaaaggtggt
    41281 gatggaaaat tgagtggatt gagaataaaa caaaagagat ttgcagatga gtacatcatc
    41341 tcaggtaatg cgacggaagc ctataagaaa gcaggttatc gtgtttctag tgatagagtg
    41401 gcaggcgttg aaggacataa gttactaaag aatcctaaga ttaaaagtta tatagatgaa
    41461 cagttgaaac agcttgattc tgaaaaaatc gcagaccagc aagaagtcct tagttatcta
    41521 acctcggtaa tgcgaggaga gacacaagaa cagactttga taagcatcgg agaattgggt
    41581 caaacgatta cggatattaa tgttggagca aaagacagaa tcaaggcagc cgaactatta
    41641 ggaaaacgtc ataggctttg gacagacaaa gtagaggcag acgtttctgg gacggtggtg
    41701 tttgcaaatg agtcagacat accagattaa acaaagtgat attgtaatcg acctacctaa
    41761 gacagtagga gctggatacg gacagttctg gcgctcaaga aatctttatc gtgttgtaaa
    41821 aggttcccgt ggttcgaaga agtccaagac aaccgctttg aattatgttg tccgtctttt
    41881 gaaatatccc tgggccaact tgcttgttat tcgtagatac tcgaatacca acaagcaatc
    41941 aacttatacg gattttaaat gggcgtgtaa tgtgttgggt gtgactcatt tgtttaaatt
    42001 caatgaatct ttgcctgaaa taaccataaa agcgactggt caaaaaatcc tattccgtgg
    42061 tttggatgat gaactcaaaa tcacatctat cacggtcgat gtcggcagtc tttgttgggc
    42121 atggtttgag gaagcatatc aaattgagac tgaagacaag ttcagtacag tagttgagtc
    42181 aatccgtggt agcctggatg tacctgattt ctttaaacaa atcacagtca catttaaccc
    42241 gtggaatgag aggcactgga tcaaacgtgt gttctttgat gaagagacta gccgagctga
    42301 tacattcgct actacaacta cttatcgatg caatgaatgg ctggatgaag tcgatatcaa
    42361 acgctatgag gatttgtatc atacgaaccc cagacgtgcg agaatcgttt gtgatggcga
    42421 atggggagtt gctgaaggtt taatctatga gaacgtgacc gtcaaggatt tcgataagga
    42481 tgaattgcta cgagatttag ctaataagtt atgtatcggt cttgactttg gttttactca
    42541 tgatccaact gctttgtgtt gttcgttgat aaatgacacg acgaaagaga tttatgtctt
    42601 tgatgaggcg tacaaggtcg gtcttataac caaagaagtt gctaagatga taaaggacaa
    42661 aggttatcat cgctcacaaa tcattgctga tagcgctgaa ttacgactga ttgaggaatt
    42721 aaggtcagaa catggtataa ctcgaattaa agagagtcgg aaaggtaagg atagtattat
    42781 ggcaggcgta tccaaattgc aaggatacgc tatttatgtg catccagatt gtaaaaacat
    42841 catggatgaa ttttatagtt actgctacca gcgagataaa gaaggcaact ggttgaataa
    42901 accagaggat aaaaacaacc acttgatgga cgctttgcgt tacagccttc aatgtatcga
    42961 aggtggaaaa gcaaccgtcc gcagacgttc tgattatggt ctatagagag gaaagacatg
    43021 taccaatatt taacctatcc acgggatgga tatgatgagg gttctttgaa gaaagacctg
    43081 atttacaaat tgataacgat acgtaacact gaaagctcac atttgaagaa gcttaaaagc
    43141 tactacttgg gtaagcatgc tatcttaaaa cacacgagac gcaacgtgaa cgcacccaat
    43201 taccagacgg tagctaatca tgccaaggat atcgcagaca tggctacggg ctattttatg
    43261 ggcaatccta tcaagtataa caatactgct gacggtgata tcgatgaact acttacagcc
    43321 tttgatggtg ctgagattga ccaagtagat gctcagaatg ctttgaacat ggctatctat
    43381 ggtcgtgctt acgagtacat ctatgctaaa gagggtttga ctgagttgga ttcaactagt
    43441 attgatccag aaaatacctt catggtctac gatgatagta ttgagcggaa gcctttgttt
    43501 gcggtctatt actatgaagt aaaagacgat acgaaagaca ctaccaagta ccaggctgag
    43561 gtctttacag aaaatctgca ctatcacatg gtgctgagaa gtacagattc aggaacaact
    43621 cagagcgagg aggcaacacc tcacaacctt ggtcaaatcc caattatcga gtatcgcaac
    43681 aatcactttg cgattggcga ctacgagcaa cagattagct tgatagacgc ttataattcc
    43741 ttgatgggta atcgtgtcaa tgacaaggag caggcagtag agtctatcct tgtcttatat
    43801 ggcacacagt tagcagacac tccagaagat gccaaggtag cgatgaagat tctttctgaa
    43861 gaaggtcttt tggaattgcc gggcgatagt gcaagagccg agttcttgaa gaatacgctg
    43921 gatgaaagtg ctacagaaat cttgcgcaca gctctgaaag aggatatcta cacattcagc
    43981 catgtgccta acttgactga tgagaacttc gcagggaata catcaggcgt agccatggaa
    44041 tttaagctga tgagccttga aatgattacc aagaccaagg aagcgaacta taagcgtgga
    44101 ttaagacaac gtattgcgat ttttgctcat tacttgggta tgaagcagat tgctttagag
    44161 tctcattcaa tcgttccaca attcagccgt ggtttgccta aaaacttgct ggaaatctct
    44221 cagattgtga acaatttgga aggtaaagtg accaataggc agcttatttc tctcttgccg
    44281 tttgtggaag accctgatgc tgaattggaa gccttggaag aagagaaaaa gaagaacatg
    44341 gaagacatgc cgatgtttaa ccaagacaac acgaaacccg aagacgaggt agaggatgaa
    44401 gaatcaggag tattgggcga agaggaaagc caatctgatt taccaacaga tggacaaggc
    44461 cgaaaagcag gcagaccagt tcgataaggt ctatcaggaa gccaagactt acttggataa
    44521 ggaagtcaat aagattttcg ataaattcca acgtgattat ggtctaagtc aggtagacgc
    44581 tagacaagtc ttgaagaaca tgaaagccaa gaaagacttg aatgaacttc gtaaggtgct
    44641 tgaagcaaga ccgaatgatc caaatatcca aagactacta gctgacttag acagtccggc
    44701 ttattctttc cgtatgaagc gtctagaacg tttgagcgat gatttagacc gtatgcgtga
    44761 atctatctat cattcggaga agacaggctc agatgccttt tatagcgacc tgatgaagga
    44821 tagttactac aaggctacct tttgacctac aacagcagac aggactagca tatggctttt
    44881 ctgggcttcc tgagagcgag attaaacatc tacagtcttt cagttgggta ggtgacggaa
    44941 gtacgtactc aacaaacatc tggaagaata cagggaagct tacatcaagc ataaaagatg
    45001 aattactcat aagccttatg acaggccgag atacacgaga aactgcacaa gcaattgctg
    45061 agcggttcaa tgtggggcag aacgatgcaa ggcgtttggt tcggacagaa tcagcctttt
    45121 ttcataacca aatggagcta ctcaactatg aggaagcgga tatagagaag tatatctttg
    45181 tggccgtctt agacaagcgt acatcacgca tttgtcagga gcatgacaat caggtctatg
    45241 atagggataa ggctgtccct ggtgtcaatt gtccgcctat gcacccttgg tgtaggtcta
    45301 ctactgtcgg atacgatgag gacgcagact acagcaagtt gaagcgcaga gcaaggaatc
    45361 cagagacagg taaagttgag tacgtgcctg ccgatatgac ttataaagag tggtatagca
    45421 agtatgttgc gaaagatgta aaaaatgaaa tacaagatta taagaaaagt gacaaaaccg
    45481 tttcaagata taatacccca aaattgtttt ctgatgttag taacgcatgg gatgaaattg
    45541 ggaggggtgg attatcgaaa gaacaacttg tagacttgct agaatctgaa tatgaattag
    45601 gtaatttttc gagcgatata gcaaaattga taggagtaag ttctgcttat atagatgtta
    45661 gtagtttagc tacttcatta gtgagacatg gacaacagta ctccttagat gagtttatgt
    45721 taataaaaga ggcggttcaa aaaccttatt tgattctaga taattcagag agggttgaaa
    45781 aatcaattat ttcatatgta aaaataccta acaaagataa ggtcattatg gaagcggtga
    45841 tggtgccacg agatgaaatg ctagtcattc actttaacaa ggtggggatt cgtcaagtta
    45901 aaaagaatga aaaaaatatg tcgacgcttt acaaaaaggg aaaataatgc tatactcttg
    45961 gtaaagatag aggttgagaa tctgtcacca acgcgccact tatagtgggt cgagaaatgc
    46021 aggagccccg acagtcctgc ctatcttgcg cttagatagt aatctaggcg cttttttgtt
    46081 gcaataaacc actataaacc gcatcgaaat ctaggcggtt ttcttatgcc ctaaccgtat
    46141 ggaatcccgt acggttttta tattgtccaa actgtaccga tgacaataaa agctgtgctg
    46201 ttccgtcgcc ggacgtaaag cgagactatc gagtggcgac gtaatcgctg gaggacaatt
    46261 atgtcagaag aaatcaatgc aactgtatct actgaatcaa ctgagactgt cgacactcaa
    46321 gaaaatgttg atacagtgca ggaagaaaag cacgaacgaa ctttcactcg tgctgaaatc
    46381 ggtaagatgc tatctgccga gcgctctaaa tgggaagctg agcaagaagc caaggaaaac
    46441 gaagctaaga agcttgctaa gatgaacgct gatgaaaaac agaaatatca gttggatcag
    46501 cgtgagcaag aactagctga ccgtgaaaag gctattgctc gtaaggaatt gaccgcagag
    46561 gctaaagcaa tgctaagtga acgtgactta cctgttgagt tagtaaatgt agtcgatttg
    46621 acaaacgcag agacggtatc tgaatctatc acctctatcc aaaaagcatg ggaagagtca
    46681 gttcagaagg gagtctctga acgtatgaaa ggtagtgcac ctatcaaaaa tgcacaaaca
    46741 gtccagcaag aagtcacgga aaaatggcgt aaagacttct tgtaataaaa gaaaagagga
    46801 aaaataaatg gcatttgaag aattaaacac agcagaatca cgcaagaaac atcttgggat
    46861 tattgaggat gtacttgcag taaattcata ttcaacacca cttgtgacat caagcgatgc
    46921 agtaaccttg caaggtcgct cttttacagt agcaactggt aacacaacag agttgaaaga
    46981 ctacaaacgt aacaaagaca acgaatttga tcacgttgaa gttgaagaaa aggtttatac
    47041 ccttgatgaa gaaaaatact ggggtcgttt cgtagatcaa ttggacgaac gtgactctaa
    47101 tggtcaagtg aatatcaatt atgttattgc ccgtcaggct gcagaagtag tcgctccata
    47161 tcttgatgaa ctacgttttg gtgcagcact tggaaacgta agtgacaatg ttgccatggg
    47221 taaaacagca ggagcgaaca acgcttataa tgcggttctt gatgtgtctg agaaacttga
    47281 tgagcttgga attacaaaag aacgcttgct cttcgtcact ccaagtttct acaaagcgat
    47341 caagtctgaa atcgttcgtc taccacatgg tgacgcagat aagaaagttc ttggaaaagg
    47401 atatgttggt gaattggatg attacacagt ctataaggtt ccttctaaat tcctgaaagg
    47461 tgttaatgcc cttgctactg ctccaggtgt tgttacatct ccagtacaag tagataatac
    47521 taagtacaac gataacattc cagggcgatt tggcgaattg gtagagcaat tgctttacac
    47581 tggtgcattt gttcttgaac acttcaagaa atacatcatc acaattgcag attctaagcc
    47641 tgctgctaaa aaatcagcac aaggtaaagt tgtaaaccgt gctaaagcgt ggaaaactgg
    47701 aacaacttac aaaaaaggcg aatcagtaac tcatgccgat aaagtctatg tagcggttaa
    47761 ggatatttct aattcagcaa ccgcaccaga cacagataca actaactgga aagaaaaaac
    47821 tggtaagaaa taggtccgag ttatgaaatt taaaatcaaa caagatttct atgattggga
    47881 atcaaatgtg aaacgactgg caggagagga acttgagatt actgaggagc gctatgccga
    47941 gctggctgac aattttgcca gcaatggtgt cgctatctca gatgttcttg aggaaatcct
    48001 ccctgaacct gagtttttcg aagaggatta atatgtctat agagttgctg aagaaaatga
    48061 caggcgaaga agatactcag cttctcatgt tgctccaaac gagggctaca aatcttatct
    48121 tgtcagagac taatcgaaca tctttgacac ctgctttaag tctcttaata cctgaggttg
    48181 ctatcgaact ccacaaccgc tcaggagcgg aaggagagca ttcaaggacc gaaggtggta
    48241 tagcagtagt ctacggagaa aacggcctgt ctacgggcct tttacagcgt atacgtatgc
    48301 atagactagc aagggtggca ggccatgttt ttgaagcaga gtagactgaa accttatcca
    48361 atgcgacggt ttgaaaagac tgtcactgag gaaggtgtcg caaaagaagg atatgtcaag
    48421 gaagctgaga caatccgtct tgagttgtgg ccagctagta gtaaactaca gtctgaattg
    48481 tatggcgagc gtgtcaatga tattttgaac gcaaatgcca acaagtcagc tacaatcaaa
    48541 gtgaaagatg gtgtgtgtat cgatagccag acagaagtga ctcacagggt tatttctaaa
    48601 aaggtctaca cacatcatca agttttggag ttagagcgtg tcagggctac taggggcaga
    48661 taggctcata gctaaatgta gacgattggc tagtaaaaaa actggagagg atatcgtctt
    48721 acgtgcggta cacaatgctg ctataaaggt tgtccaagct gatgcaagaa gactcgcacc
    48781 agcgagagat ggagagctta taattagtat caaaactaga gcaaaaatgg acggagataa
    48841 ggctataggc gaagtttaca ccaaccttaa atacgctcct tacgttgagt ttggaacagg
    48901 accaatagga caagctaacc attcgggtat ctctccagag gtcagcgtaa cttacaagtc
    48961 taatccttgg tatgtgcatg aagaccaaat caatgtagga ccgtaccact ttcaaaagat
    49021 tggggagttc tacaagatgt atggtcaacc tgctcagcct tatctttatc cagctttgag
    49081 agacaatcaa gagcgtgtgt ctaagaatat ttcgaattat gtccgtagaa agataagaga
    49141 acaaatataa tgatcaatat caagcctgtt atttataaag aattgcaaaa ggtcgcagat
    49201 aatgtgactg atacttatcc tagcgattgg gagaatttcc cagtcgttat ttttttagaa
    49261 gaacaaaaca agccaggtga ttggtttgac gacaaggaac aaaaatcctc tattcgctat
    49321 aaggtggata tctttgatga taccagcact agtgagttag ctgttaaaat caatcagatt
    49381 tttgagtctt taggtttgcg aagaaccgac tgccaagacg tgccagatcc gtctcatttg
    49441 agacataagg tcatgcgctt tgaaggtgtc gttgatttag actcagagct tgtttttcaa
    49501 tttagaatgg agaattaaac atgttagcaa atggaattaa attggccttt agtgaaacga
    49561 aaggcaatta tcagaatctt gtagggctta aggaagtacc tgaatttggt atcgagcccg
    49621 aaaaagtaga aaatactact cttgcagata cggtgaagaa gtacgagttt ggtatcgggg
    49681 acgcaggaga acttaagtac aagttcgctt ataataattc aagcgcaaca gctccttacc
    49741 gtgtattacg taaggcagca gatggcaaga aaaaactcta ctttgaacaa acctacccag
    49801 acggtactaa ggtcactttt gaaggtcaag tatccgttaa actgggcggt ggcggcgtta
    49861 atgccgttat cgagttcaca cttaagattg cattgcagtc tgaattgaca ttcgttgatg
    49921 gaattggagg ttaattaaat ggcgttaaaa tacacaactt ggaaagttac tgacgaaaaa
    49981 gagttgaagc tacgtttgac atctcatcaa gctgcaactg tggaagaaaa aatcggcatg
    50041 aacttgttaa agattttcat gcctgaagct ggcgaagagt tcactttacc gcctttgaaa
    50101 gttatgctgt tgttagttca tggagccttg cagcagtatg aacatgggta ttcctttgaa
    50161 gatgtctacg acctatacga tgaatacgtg gataacggcg gagaccaaac aaccttcatg
    50221 acagaggttt taatgccact ctttgaagta tcgggtttta ctccacgagg aagcaagggc
    50281 aagaaagctt ccaagaagaa aatgacagta gtcgagtaat cttaacggta acgcagatta
    50341 ttgagaggct ttaccctatg tttttggaca tcgggggtaa gcctcttgat ttttgggatt
    50401 taacggtgct tgaaatcagg gaaatgattg aaagctacaa ccgtgtcaaa atccaagagc
    50461 gtaaagagaa gattattgac tcatacatac tttcgagaat gataactaat catgtttcct
    50521 tattactgtc caatgacgct aagattgctg agctttggga atatgcgcct gatttgtttg
    50581 tagaagagaa acaagcggta gaacaagaac gacaaagaca agcacttttg ttgcataagg
    50641 aacggatgcg tgattttgca gagagacata atcgaaaaag gaaggaggaa gtaaatggca
    50701 actcttgacg aattgaaagt catgattgac gctgagatag cgcctttcag gaaaaagatg
    50761 aaagaagtcg agaatcaggt caaaggaaca tctgaccaag tgaaaaatgc cactgccaaa
    50821 gttcgtgaac agtcgaattc aatcggtagt acgtttggta agctcgctaa gtttgctggt
    50881 tttgcaatcc ttggtaagaa attgcttgat gttgggatgt attcaacgca gacagctctt
    50941 gaagtatcag cgtctatgaa ccaaattaag cgacagatgg gtgagagttc gcaatctttc
    51001 ttaaaatggg ttaacgataa cgctaatgcc atgaatatgg gtgtgggcga ggctactaac
    51061 tatggtgcag tctactcaaa cttattttct ggatttatca aagacaccaa caagctaagc
    51121 gcttatactg ctaagatgtt gcagacgtcg gcagttgtcg ctgaaggctc agggcgcacg
    51181 attacagacg ttatggagcg gattcgctca ggtttgctag ggaatacgga agcgatagac
    51241 ttttgtcgca ccgcttagaa ataggcggat taagaactta ccaaaatcgg taaaactcta
    51301 aattttaagt aattaaaaca tgacgatacc gaggtaaact aagcaattaa aaaggcttag
    51361 tcaccgtaga gcatagggat tgaacctgtg ctttttgttt tgtcaaaaag tatagaataa
    51421 aatatcccca cgagtggtga gcacctagac aattcggttg taggtgaaaa tatatgccga
    51481 acttacaaga aattgtaaga agtatggata aaaagccatg cgataacatt attgagaaga
    51541 tctaggaatc aacgtcaatg tggctatgat tgagtccact gaagccttta agaagttcgc
    51601 aaacggacaa agctggcaac aattagacta ccaaacccag caacaaatcc gccttatggc
    51661 tatcctggaa caggctacag ccaagtatgg gaataccttg tctaattctg taaatggtcg
    51721 tatcagcctg tttaagtcgc ttatgaagga cgcagcattg aaccttggta actctatgtt
    51781 accgattatc aatgccatta tgcctgtctt gaactctttt gctatggttt tgaagaacgt
    51841 gacggctaaa ctcgctgagt ttatcgcttt gatgttcaac aagaaagcaa cagtgaaaga
    51901 tggtgttggt ggagcagttg gagacatggg taacgccatg aaagacgctg caggcggagc
    51961 aggagacctt gctgacgcag tagacgatgc tggagattca gcaggaggac ttgctgacaa
    52021 tcttggagac tccgccaaaa acgctaagaa agctgctaaa gagttgctag gtcttttggg
    52081 atttgatgag attaacatct tgcaaaaacc aaaagacgac gatgcaggcg gttctggagg
    52141 cggtggcaaa ggtggtaaag gaaagggagg cggtggcgga cctttcaaag acatcttgcc
    52201 agaagtcgag ttgaccgaca tggacaacca attcaagagc attttcgatg gccttgggga
    52261 taagctgaaa gggttgtttg attatctaaa aaaactctgg gatttattta aaaaaggttt
    52321 ttctctatcc tttagatggg atagtattga aagattaaag aatgcactac aaggcatttg
    52381 gaaatctatt aaagatatct ttgaagatgg tactgtattg caagcagctg caaggtttgg
    52441 agaaaagcta gcttttgctt taggacaaac gacgggcgct ctcgctaacg taatcatggg
    52501 tattgctgtc tttatcgctg aaagtctgaa taaatcactt aatgaaacga aactagatat
    52561 caaagcatgg ttaattcgta tgtttgatat tggtggggaa atcgtcgaaa gcgtcggaaa
    52621 tattgcccag agtatcggac aaattttcta cgattcaatt acaagtgaac tagctacaaa
    52681 tatgggcgca ggcctattca gtgctttcac atacgctttt atgggcgtga aagagataac
    52741 cgctaaatac acaagggata taatcggagc tattgaagaa actatcaccg aaaatcaggc
    52801 tggcataaca gaaatgttta cgggtctttt taaagctgta gatcctattg ctcaagcttt
    52861 atcaagctca atgaagaaac tttttgaaag tgttaattaa gtatacgatg agcatataaa
    52921 acctttgttt gaatcaagtt ccgccttgat gtcagatgta gttggtgctt ttgttaatgg
    52981 atggaatgat aatatccaac ctgtccttga aaagataggt cacggtttcg ccgatacaat
    53041 caaaaaccat attgaaccag ctttagaaaa aataggtggc atgattggaa gttttgccga
    53101 cttttctaaa gcgataaatg aagttttcgg cccagtcatt tcctttattg tagaaaagtt
    53161 aacggttgta ctagcccctg caattgaata cataagagaa gtttggcgtg ttttatttaa
    53221 cactatctct gatgtgattg gtggtattgc tgatatcatc aaaggggtat ttgatgtact
    53281 tacaggactt ttaactggag atggcgaaaa aatcaaagaa ggatttttga gtatatttgg
    53341 cggattaaaa gatatagtag ttagcgtctt tagtggcatt attgatcttg tatctggtgt
    53401 attgaaactg ctttgggacg ttgttgtcgc aatattcaaa agcatttggg acgcaattgt
    53461 agctatcttt tctggtgtca gctcttggtt tggagaaaag ttccaaggtg catgggatgc
    53521 tatcgttaac atcttcagta atctaggctc atggttcgga caacgttggg cggatgtgac
    53581 tagtgcttta gctaatatcg gggcatggtt tacgaatatg ttccaaaaag catggactgg
    53641 cttaacaaac atctttagca aactaggttc atggtttggc gatagatgga acgatgttac
    53701 aagtgcgctt tctaaagtag cgagctggtt tggcgagata ttcggaaaag cttttgacgc
    53761 agtaaaagat gcttttagtt ctattggcga cttctttaaa ggcgtttggg atactgtcaa
    53821 aagtatcttc gttaatgctg gtcagatggt cggcgaggca gtaggtggag cgtttaagag
    53881 tgcggtcaat gcggttcttg gaacgattga aaatgtagtc aatggtttca tcggaatgat
    53941 taatggagtt ttaggcgttg tcagaaactt acctggtcta ggatgggttg gtagtgtaag
    54001 cacagttagc ctccctcgtc ttgcccgtgg tggtatcgtc gatagtccaa caatcgccat
    54061 gattggtgaa gctggtaaag aggcggtcgt accacttgaa aatacaggat ttatccaaac
    54121 acttggacga gtagtcagca gtgcggtagt aaatgccatg gctggtgtta gtccacaagg
    54181 tggattctct ggcgacggcg acatcgttat ccaaatcgca ggccatgagt tcggacgggt
    54241 agccatccaa gaaatcaaca aggaacatga acgagcaggt caaaccttgc tcaagattta
    54301 ggaggttaaa tggcacaatt gacaatcaat ggggtggctg tgaagcctcc caaatctttt
    54361 caagtcggta ttcaagatat cgatggagag acagggcgta atgccaatgg cgatatggtg
    54421 cgtgaccgta tcacgaccaa acgaaaacta gactgtgaat ggggcatgct gactcaggaa
    54481 gaaatgagtc agcttttaaa tgctgtttca gcagtctttt ttgaggtctc atatcctgac
    54541 cctgttaaag gtcagacgac tgggactttc tacgtcggtg ataggacagc tcctagctat
    54601 agctttactg agaagtttaa accttggtct ggcgctaaat ttaatctggt agagaggtga
    54661 gaaaatggac gctttaatca gacgacagtt tgacagagct atgtttgcca aggataggac
    54721 gctggctatt cgtgttggtg attatgcttc acgagatatc aaagaggcta gttttgagta
    54781 tggctatatc aaaggcgata cttacaaacc cggtggaacg tgtgccggta gcggtaagat
    54841 tacctttacc agtatcatta ccacgttcaa taaactggat atactacacc ctgagattgg
    54901 tctattggtt gggactacct accagtgggt taagatgggg gaatacttca tcaatgatat
    54961 tgagattgac cgaaaccgaa acacaaccac gcttgaactc atggatggta tgtttaagct
    55021 caatcgtgag tatgtgacgg acttacattt tccagctgaa gtacgagagg ttattcagga
    55081 aatctgcctg aaaacaggca ttgagttagc gaatgactat ttcggaatca gcgctatgcg
    55141 ttaccatatc gagcaagttc ctgagggcaa gaaactttcc tttagggata tgctgagcgc
    55201 tatgactcag atgattggga tgtcttgttt cttcaacaga gaaggcaaga tggaaatccg
    55261 tgatttgact gagtccaata tcacgatcaa cgctgacagt tacttcttgt atggcttgac
    55321 caagagtgag attgagtatc agatatctgg tatcacttgt aagacggaca agaagtctct
    55381 gacggtcggt atgaagacag gtcggtcttt ggaactggac aatgtcttca tgacccagag
    55441 cgctttaaat gacctgtatt acaaactgaa aaacctaact tactatccgt ataatctcaa
    55501 ctaccaagga catttgttac ttgaggttgg gcagtgggta accattcaga ccaacaagaa
    55561 agagactttt aaagttcccg tgttaagtca gagctttacc tttaaaggtg gtctgagagg
    55621 tcgtatcagt gcagatagta aggccggaaa cgatacccag tattcttacg agggtacgat
    55681 taccaagcag attaagcaac aagatggcat tgaagccaaa atccaagcgc agattgaagc
    55741 agcagataaa gattctgacc aaaaggtcga caaaatcaaa aaagacttta acgatcaagt
    55801 agaacttgcc aaagccagag ctgaagaagt caagcaagaa ctgtctgaca ctatcaatca
    55861 gcgctttaat agctttgaca acgggccatt gaaagaaact aagcgcaagg ctgaggaagc
    55921 tttgcgaaat gctggcgcaa gtaccctgct tgcacaggaa gttaagcgga ttggactgga
    55981 ttctgtcgct agacttggag cgtttaagtc gcagactacg agcgcacaaa cggctctgtc
    56041 aggtgacttg gacgctctga aacagacggt cacaagtgag gtcaatcaag cttcagagta
    56101 ccgcagaacg accacagagg tccttagtcg catgactggc cagatggacg gatttgcgac
    56161 gaaatctgaa gttagacaag atgtggctgg tctgacagag acatttgcta aacttaaaac
    56221 tgatacgaat aatttgattt ctggagctaa aagtgaaatc actctagcaa aaacagaatt
    56281 tcagaaaaca gctgatggcc tatctgctaa gatgtcagca gttgagcgtt acgttaatca
    56341 agatggtcag cgacaggaag ccctacagcg ctatactcgt gaggagagcg ctcgtcaagt
    56401 cagcgcggtt cgtgagcaga tatccagaga ttatgttggg aaatcggctt atcaagaaga
    56461 tgtgagaggt ctagaacgtc gatttagtgc gataagcacc cagacgaaca atgatatagc
    56521 taggaaaatc gctcagtaca agcagacagt cgatggacaa tttgcaagta ttacgtctca
    56581 aatagctggt aaggctaatc agactgactt ccagcgtgtt aaggaaacca gtaaacttta
    56641 cgagcggatt ctgggtaata gtaaaaacgg gattgcaaat acgattgcaa gaatggctat
    56701 gacccatcag ctctttcagg ttgaagtatc gaaaaacgac catctgaaaa ccgttcagag
    56761 gcagctggca ggttcctggt cggttcaaaa catcaacagt gcaggtgatt tgatttcggg
    56821 cattaatcta ggagccaatg gacataaccg ctttgttggg aaattgaccc acatcactgg
    56881 cgagaccctg attgacagag cagtcatcaa gtctgccatg gttgataagc tcaaaacggc
    56941 caattttgaa gctggttcgg taacgactac gatattagac gctgaagcgg tcacggctga
    57001 taaagtgaga tttgatgctg cgtttattag gaaaatgact gcaaatgacg cttttattga
    57061 ccaactgaca tctaaacgta tcttctctac taaggttgag tccgtcattt ctagttcaac
    57121 cttcctagaa gcctatcaag gacgaatcgg tggattcact attgggcgtt ttgctcaagg
    57181 aagaggtcgc tggatttctg gtatcaacca attctcagtt ggcatgggga atggtgaagg
    57241 aggaggctat aatggcgaaa ataccgcatt ttgggcgaac tggggttaca gttggaactc
    57301 tcctggcccc aatgcttggt atgtaacaac atcaggaaat atgtattgcc gaaacggagc
    57361 agatttccat gggaaggttg acttttcgaa ttcatcgaga gcaaactttt atgggaatac
    57421 tactttttct cgttctcctg tgttttcaaa tggtatcgaa cttggaagta aagacgtctt
    57481 tggtgatggt tggaatccca aaggcggaag gaatgcggtt gtttggtgga atcaggtcgg
    57541 tagtggtagc gtgaagtatt ggatggaaca aaaatcagac agacgcctaa aagagaacat
    57601 cacagataca gctgtgaaag ccttggacaa aatcaacaga ttaagaatgg ttgcatttga
    57661 tttcatcgaa agtaagaaac atgaggagat tggtctaata gctcaagagg ctgaaaccat
    57721 cgttccaaga attgtttcac gagatcctga gaatccagat ggctatctac atatagacta
    57781 taccgcttta gttccttact taatcaaggc cattcaagaa ttaaatcaaa aaatagaaaa
    57841 aatggagaaa acaatagcat gaataacaac atgttgacca atatcgcact taaagcaatt
    57901 caggagcttg ctcttgaaaa tagaaaacga acagatagat tggagaactt agaaaatgaa
    57961 cgcagaacag cttaaccaag ccttacaaat gacaattagt gaaatgtcaa caacttcaac
    58021 aaattcgatg attacaagta atgtcttgag tattcagttg gatgagcaaa gggaagagaa
    58081 tcaaagactt caagcacgag tggatgagct ggaagctctg cttgatgaac aaactaaacc
    58141 agcagacaaa ggagaataga catggcaaaa acaattcaaa acacagataa cttgctagac
    58201 cttacaaaaa tcacagaacc atttgatctt gcgagtgctt tgcgctacat gaaagaaagt
    58261 ggagagttca ttcgttgcaa gaatgtaaac gatgacttct atatgtatcg tgatgttcaa
    58321 aaacgtcctg tgttcgtaaa tggccgtcgc caattcaagg atgttgaaac cgtttgggcg
    58381 ttcaaccagt ggggtggtac aatcacaaca atcaacgtag ccattctgtt gaatcaggaa
    58441 ttctatatca tgaaatttga tgcagagggc aatcctgact ggacggatcc aacggtagaa
    58501 cctaaagaat aggaggttgt atgccaattg aagaagctga aaaaatcgct caaagtcagg
    58561 tagcttgggc gattttgttt atcttgcttt tctttattat cattcgatat cttatcaaga
    58621 cttcggacaa gcgagagaag aagattatgg atttgcacga gcaatcaaag gccgactcta
    58681 atagacgaga agagcgtttg atgactcatc tagaaaagac cactacagaa ttaaccacaa
    58741 tcactcacgc ggtcggagac attcaaaaag aaatggttcg catgaacgac cgcatggaag
    58801 aaatcgaaaa aggagaataa caaatgcaac aaattactga aatcattact aatggagcaa
    58861 tcagcatcct agtcattttg gcaggggttg tagttagggc agtcaaggaa tacctcgtca
    58921 aaaaaggtgg agaaaagact atcaagattg ttgaaatctt ggccaagaac gcagttaatg
    58981 ccgtggagca ggtagctgct gaaactggct acaagggaga tgaaaaactg gcacaggctc
    59041 gcgctaaaat tcgtgctgag cttacaaaat acaatattag catgactgac aaagacttag
    59101 acaccttcgt agagtcagca gtgaagcaga tgaatgacgc atggaaagga cgatagggaa
    59161 tggatatcga tagaaacaga ctacgtacag gcttgccaca ggttggggtg cagccttatc
    59221 gacaagtaca tgctcactca acaggcaacc gcaactcaac cgtacagaat gaagcggatt
    59281 atcactggcg gaaagaccca gaattaggtt ttttctcgca cgttgttggg aacggtcgca
    59341 tcatgcaggt aggacctgtg aacaacggaa gttgggatgt tgggggcggt tggaatgctg
    59401 agacctatgc agcggttgaa ctgattgaaa gccattcaac taaagaagag ttcatgacgg
    59461 actaccgcct ctatatcgaa ttgctacgca atctagcgga cgaagcaggc ttgccgaaga
    59521 ctcttgatac agacgacttg gcaggtatca agacgcatga atactgtacc aataaccaac
    59581 caaacaacca ctcagaccat gtggatccat atccatatct tgcaagttgg ggcattagcc
    59641 gtgaacagtt taagcaagac atcgaaaacg gcttgagcgc tgcaacaggc tggcagaaaa
    59701 atggcactgg ctactggtac gtacactcag acggctctta tccaaaagat aagtttgaga
    59761 aaatcaacgg tacctggtat tatttcgatg gctcaggcta tatgctttca gaccgctgga
    59821 agaagcacac agacggtaat tggtactact ttgaccaatc aggcgaaatg gccacaggct
    59881 ggaagaaaat cgctgagaag tggtactatt ttgatgtaga aggtgccatg aagacaggct
    59941 gggtcaagta caagaacact tggtactact tagacgctaa agaaggcgcc atggtatcaa
    60001 atgcttttat ccagtcagca gacggaacag gctggtacta cctcaaacca gacggaacac
    60061 tggcagacaa gccagagttc acagtagagc cagatggctt gattacagtt aaataaatag
    60121 aaaggaaact ttctaaattg ttctttcacc gcaggctcag gcttgcggtt tttttgtttg
    60181 ctcaaaaggg gcaaaaaagg ggcaaaagtg tcgtaaatct ctgtaaaatg atgtaaaaac
    60241 atttatttaa aagctcaaaa tatagctgtt ttaaaaggta ttgtaagata tagtaaaacg
    60301 atgtaaaggt atttttaaat gcggatgaat tataaaacca cgaatcctat gtgactcgtg
    60361 gttctttttt ataaactggt agagtgtttt ggttgtactt tttgttcagg gtcaatgtag
    60421 ttgatagcgt tgttgacagc agttggagct tctccgaggc ctgtcgcaat cagatcaatt
    60481 tttccgtcat agtagcagca gtcaccgata gcatagatac ctgcttggct ggattcctgt
    60541 ttgctgttga cgataatctt gtgacggttg aggtcgagcc cccagttttt aaggttaccg
    60601 acagaagatt tgaaaccata gttgacaaag aggtggtcta ggtcaatggt ttcagtttca
    60661 tcagatttga cttttgtgat ttcaagttta tcaagcgttt ttccatctcc aaggagttgg
    60721 ctaggggtga atggtgtctt gatggttaca gatgattctt gcaaggcttg aacactgtgt
    60781 tccaaggcac ggaaattatc tctgcggtga acaagggtag ttggtgcgat tttttcaaaa
    60841 gccaaagtcc aatccacagc cgaatctccc ccaccaagaa tcgtcacttt cttaccagcg
    60901 tattgctgaa tgttagaaac gtggtagtgg atattttcat agccctcaac cccttcaagt
    60961 tccagcggac gtggtttgaa ggcaccgccc cccatagcga tgataactgt tttagtcagg
    61021 tgacttcctt tagaagttgt gatggcaaat tcttcttctt gtttgtcaat ctcaagaacc
    61081 gtttcattga gatgaatagg ggtatcaaat ccatttagct gttcaatcaa gcggttagtc
    61141 aactcttctc cagtcaggtt tgggaagcct ggtacgtcta ggatttcctt ttcagggtag
    61201 agaatagcag gttgtccacc tagctgggga agagagtcga tgatttgaac cttggcttgg
    61261 cgtaggtggg cataaaaggc tgcaaaaagc ccgacaggac caccacccac aatggtaata
    61321 tcatagagtt gagacatagt ttctcctttg ttttttctag tcagtttatt ttatcatatt
    61381 tttgttcaat ataaaatgga ctaggatagg gaaaaaaatg ccagaaaatg gtataatagg
    61441 acgaaagtgt tttgataggg aggatatcag ggatgaattt tcaacaatta tccaatctgc
    61501 aatattggac cagtttgttt gcaagtccat ggacgatagc tatcaatctg attgatattt
    61561 tgattgttgc ttatatttta taccatttta caaaaactat tgcaggaacc aagattatga
    61621 ttttggtacg tggagttttg gtgtttattt tagctcaaat ccttgcaaat atgattggtt
    61681 tgactacgat ttcttggtta atcaatcaaa ttattactta tggggttatt gcggcggttg
    61741 ttattttctc tccagagatt cggactggtt tggaacgttt gggaagagcg acagatttct
    61801 tttccaatgc ccctattagt gctgaggaac agatgattcg tgcctttgtt aagtctgttg
    61861 aatacatgag tcctcgtaaa atcggggcct tggttgctat tcagcgtgta cgtaccttgc
    61921 aggagtatat ttcgacagga attcccttgg atgctaagat ttctgcagaa cttctcatta
    61981 acatttttat tcccaacact cccctacatg atggtgcggt gattatcaaa gaagaacgta
    62041 tcgctgtgac gtctgcctat ctgcccttga caaaaaacac agggatttcc aaggaatttg
    62101 ggaccagaca tcgggcggct atcggtttat cagaagtctc agatgccttg acttttgtcg
    62161 tatcagagga aacgggagga atttcgataa cctataatgg aaggtttaag cacaacctaa
    62221 cacttgatga atttgaaaca gaattacgtg aaatcttact tccaaaagag gaagtgggtc
    62281 ttagttttaa agaacgattg ctaggaggat ggaaacatga aaaaaaatag tttatatatc
    62341 atatcctcac tcttttttgc ttgtgtttta tttgtctatg ctacggcgac gaattttcaa
    62401 aacagtacca gtgctaggca ggtaaaaacg gaaacctata ctaatacagt aacaaatgtc
    62461 cctattgaca tacgctataa tagtgataag tattttatta gcggttttgc ttcagaagta
    62521 tcagtggtct tgactggtgc aaatcgccta tcgctagcta gtgaaatgca agaaagtaca
    62581 cgtaaattca aggttactgc tgacctaaca gatgccggtg ttggaacgat tgaagttcct
    62641 ttgagcattg aagctttacc caatgggctg accgctgtgg cgactccgca aaaaattaca
    62701 gtcaagattg gtaaaaaggc tcagaaggat aaggtaaaga ttgtaccaga gattgaccct
    62761 agtcaaattg atagtcgggt acaaattgaa aatgtcatgg tgtcagataa agaagtgtcg
    62821 attacgagtg accaagagac attggataga attgataaga ttatcgctgt cttgccaact
    62881 agcgaacgta taacaggtaa ttacagtggt tcagtacctt tgcaggcaat cgaccgcaat
    62941 ggtgttgtct taccggcagt tatcactccg tttgatacaa taatgaaggt gactacaaaa
    63001 ccagtagcac caagttcaag cacatcaaat tcaagtacaa gcagttcatc ggagacatct
    63061 tcgtcaacga aagcaactag ttcaaaaacg aattaaaaat agaaaaggat tttataacaa
    63121 tgggtaaata ttttgggact gatggagtcc gtggagaagc taacctagaa ctaacaccag
    63181 aattagcctt taaactagga cgttttggag gctatgttct tagtcaacat gaaacggaag
    63241 cgccgaaagt ctttgtagga cgtgacacac gtatttcagg ggaattgctg gaatcggcct
    63301 tggtggcagg tctcctttca gtagggattc acgtatacaa acttggtgtc cttgcaacac
    63361 cagcagtagc ttacttggtt gaaactgaag gagcaagtgc cggtgtcatg atttctgcta
    63421 gccacaaccc agcccttgat aacggaatca agttctttgg cggtgatggc ttcaaactag
    63481 atgatgaaaa agaagcagaa attgaagcct tgctagatgc tgaggaagac actcttcctc
    63541 gtccaagtgc agaaggctta ggaattttgg tagattatcc agaaggcttg cgtaagtatg
    63601 aaggatacct tgtttcaact ggaactcctc ttgatggaat gaaggttgcc ttggatacag
    63661 ctaatggagc agcttctacc agtgcccgtc aaatctttgc agaccttggt gcccaattga
    63721 cggttatcgg ggaaacacca gacggtctta acatcaacct taatgttggt tcaacacatc
    63781 cagaagccct tcaagaagtg gtcaaagaaa gtgggtcagc tattggtttg gcctttgatg
    63841 gagacagtga ccgcttgatt gctgttgatg agaatggtga catcgtcgat ggtgacaaga
    63901 ttatgtacat catcggaaaa tacctttctg aaaaaggaca attggctaaa aatacaattg
    63961 tgacaactgt gatgtctaac cttggtttcc acaaggcctt gaatcgcgaa ggtattaaca
    64021 aggcagttac tgcagttggt gaccgctacg ttgttgaaga aatgagaaaa tcaggctaca
    64081 accttggtgg tgaacagtct ggtcacgtta tcttgatgga ttacaatacc acaggtgatg
    64141 gtcaattatc agcagttcaa ttgactaaaa tcatgaagaa aactggtaag agcttatcag
    64201 agttggcggc agaagtaacg atttatccac aaaaattagt taatatccga gtggaaaacg
    64261 tcatgaagga aaaggccatg gaagtgccag ctatcaaggc catcatcgag aagatggaag
    64321 aagaaatggc ggggaacggc cgtatccttg ttcgtccaag tggaacagag cccctcttgc
    64381 gtgttatggc agaagcgcct acaacagaag aagtggacta ctatgttgat accatcacag
    64441 atgtagttcg tgctgaaatt gggattgact aaatcctaga aaactagatg aaaataaaaa
    64501 attatggtac aatagcttat aatattgtag ccgatggaga aagacatgaa tcttaaacgt
    64561 gaacaagaat ttgttagtca gtatcatttt gatgcgcgta attttgaatg ggaaaatgaa
    64621 aatggagctc ctgaaaccaa ggtggatgtg aatttccaat tgctccaaca tgaccaagaa
    64681 aatcaagtga cttccttgat tgtcatcttg agctttatga ttgtatttga taagtttgtc
    64741 attagtggaa caatctcaca agtaaaccat atcgatggcc gtattgtcaa tgaaccaagt
    64801 gaattgaacc aagaagaggt ggaaaccttg gctcgtccat gtttgaacat gctcaatcga
    64861 ttgacttacg aagtgactga aattgcatta gacttaccag gaattaattt ggagttctaa
    64921 tatgaaatta gctgttttca cagattcctc tgcttatctc agtgaagaga ccttgcaaag
    64981 agaagacttg tttgtcttgg atattcctgt caatattgat ggtgaggaat atgtcgaagg
    65041 catcaatctg tctgctgagg aattttacca aaaaatggct caggcttctg aattgcctaa
    65101 gaccagtcaa ccaagtattg ccaagttaga tgagatttta acttcgctca aagaacaagg
    65161 ctatacacat gccttggggc ttttcctatc ttctggaatt tcaggttttt accaaaatat
    65221 ccagtatatg gtcgatgact atgagggctt aaccattgct tttccagaca ctttgattac
    65281 aagtgctcct ctgggtatca tggttgaaag cgtctttaat tggcgtgatc agggcgatga
    65341 ttttgccagc attcaggata agctagccat tcaaatcagc cgtacgtcag cctttatcat
    65401 ggtagatgac ttggatcatt tagtgaaagg tggacgcctt tcaaatgggg ctgccatttt
    65461 gggcaatttg cttagcatta agccaatcct ttattttaac gatcaaggtg tgattgaagt
    65521 ttacgaaaaa gttcgtactg aaaagaaggc caccaagcgc ttaattgaaa ttatcaagga
    65581 aacaacggct tcaagtcaat acagggtcat tgtcattcat gggaatgctc ctgaaaaggc
    65641 tgaagaattg cgtcagcatt tgcttgattt tggcttgggt tcggatgttt cacttgctac
    65701 atttggtagt gtcattggaa cgcacctagg agcaggaagt attgctctgg gttatattcc
    65761 agtgatttag ttggcgcttc taggctagtt aagatgcctt gtatcttagc aattgaacac
    65821 ggactacctg cctcttgaaa aaagatgtct gtcttgcctt tcgtggaaag tcagtgccat
    65881 ttcctatttt ttatgggtgg ctaagatcct ttgtatcttg ataattgaac acgcctggaa
    65941 ccctgtgtga aaaagatagt tcttccaagg agtagacact tcttgatcag aattcctatt
    66001 ttcactttgt gttcttacag gctttgtatc ttagacagga gtagagatga gtattcgagt
    66061 aattattgcc ggttttaagg gaaagatggg tcaagctgct tgccagatgg tcttgactga
    66121 ttcagatttg gacttggtag cagttttgga tccttttgag tctgagtcag aatggcaggg
    66181 tattcctgtt ttcaaggata aggctgattt agctggtttt gaagcggatg tctgggtaga
    66241 ctttactact ccagctgttg cctacgaaaa tacacgtttt gctcttgaaa atggctttgc
    66301 tccagtagtt ggaacgactg gtttcacgag tgaagaaatt gcagagctaa aagaattttc
    66361 tcgtgcccaa gacttgggtg gcctgattgc ccctaacttt gccttgggtg ctgtcttact
    66421 catgcaattt gcgacgcagg ctgccaaata tttcccaaat gtggagatta ttgagctcca
    66481 tcatgacaag aaaaaggatg ctccgagtgg aacagccatt aaaacagctg agttgatggc
    66541 agaggttcga gagtcaattc agcaaggtgc agcagatgag gaagagctga ttgctggtgc
    66601 tcgtggtgct gactttgatg gtatgcgcat ccactcagtt cgtttgccag gcttggtagc
    66661 tcatcaggaa gtcatctttg gcaatcaggg agaagggttg accctccgtc atgactccta
    66721 tgatcgcatc tccttcatga caggagtcaa tttgggaatt aaagaagttg tcaagcgtca
    66781 tgagcttgtc tatggattag aacacttatt atgagattaa cgcaaatgcc ttctgaattt
    66841 cagaaggctt taccagtatt agaaaaaatt aaagaagcag gctttgaggc ttattttgtt
    66901 gggggctctg ttcgagatgc ccttctccat agccctatcc acgatgtgga tattgcgacg
    66961 tcttcttatc cagaagagac caagcagatt tttccgcgaa cagccgatat cggaatcgag
    67021 catggaaccg tcttggtctt agatggggat gaggagtatg aggtaacaac ctttcggaca
    67081 gaggatgtct atgtggacta tcgcagaccc agtgcggttt cctttgtgcg ctcgctagaa
    67141 gaagacctca aacgccgtga tttcacagtc aacgcctttg ccttggatga gacaggagaa
    67201 atcgttgact tgttccatgg tttagaagat ttggaaaagc aagtcttgcg agcagttgga
    67261 gtggctagtg agcgtttcaa cgaagatgct ttacggatta tgcgtggttt ccgttttcag
    67321 gctagtcttg gttttgcact tgagccagaa acatttaaag ctatgaagac cttgacgccg
    67381 cttttggaga aaatttctgt agagcgtacc ttcgtcgagt ttgataaact cttgctggct
    67441 ccattttgga gaaggggctt ggcttccatg attgagagtc aagcttatga ctatctccct
    67501 gatatggcat ctagccggga caagctcaac agactgtttg atttggagac tgattttact
    67561 tttgaatcct ctgaacaagc ctggtcggct ttactatggg ctttggagat tgaaaatgcg
    67621 cagtcatttt tgaaattttg gaagacctca cgccagtttg ccaagcaagt tcaggatttg
    67681 ctgattattt tggctctgcg tgaaaatgga gaattgagca agcgagattg ttatcgcttt
    67741 gacatagatt tgcttttaca ggctgaaaat cttcgtcaag ctcaaggaaa agaagtcaac
    67801 ccacaagcca tcacagaaaa ataccaaagc ttgactatcc atgacaagaa agagattcag
    67861 attaatggcg gtattttgat caaggaatat ggctatcagc caggcccaga cttgggagag
    67921 attttaacag agattgagtt tgccattgtc gatggagaat tggagaataa tcgtgaagcc
    67981 atccatgctt acctgaggga gaaaaaatga gtgattttat cgttgaaaaa ctaagtaaat
    68041 ccgttggtga caagaccgtt tttagggata tttcctttat tatccatgac ttagacagaa
    68101 ttggtttaat cggtgtcaat ggaactggca agaccaccct tttggacgtc ctttctggtg
    68161 tttctggatt tgatggggat gtcagtcctt tttcagctaa aaatgattac cagattggtt
    68221 acttgactca ggatcctgat tttgatgata gaaagacagt tttggatacg gttctatcta
    68281 gtgaactcaa ggaaatccag ctcattcgtg agtatgaatt gattatgctc gactatagtg
    68341 aggacaagca ggcgcgtttg gaacgtgtca tggcagagat ggactctctc caagcttggg
    68401 aaatcgagag tcaggtcaag accgttctta gcaaattggg cattcaagac ttatctactc
    68461 ctgttgggga attgtcaggt ggtctgagaa gacgggtaca gttggcacaa gtcttacttg
    68521 gcaaccacga cctcttgctt ttggatgagc cgaccaacca tctggatatt gcgattattg
    68581 agtggctgac cctctttttg aaaaattcta agaagaccgt cctttttatc actcacgatc
    68641 gttatttctt agacgctttg tccacacgga ttttcgagtt ggagcgagca ggcttgacag
    68701 aatatcaggg caattaccag gactatgttc gccttaaggc agaacaggac gagcgcgatg
    68761 cagctctact tcataaaaaa gaacaactct acaaacaaga actggcctgg atgcgcagac
    68821 aaccgcaggc gcgtgcgacc aagcagcagg ctcgtatcaa tcgtttccac aacttgaaga
    68881 aagaactttc aggtggcgtt gctgagacag acttaactat gaactttgaa accagtcgga
    68941 ttgggaagaa agtcatcgag tttcaggatg tttcctttgc ctatgaaaac aagcccattt
    69001 tgcaagattt taatctcttg gtacaggtca aagatcgtat cggaattgtt ggggacaacg
    69061 gtgttggaaa atcaacctta ctcaacttaa ttgcaggaag tcttgagtca actaaaggac
    69121 aagttgtgat tggggaaact gttcgcatcg cctatttctc tcagcaaatt gagggcttag
    69181 atgaaagcaa gagagttatc aattacctgc aggaagtggc agaagaggtc aagaccagtg
    69241 gcggttctac gacttcgatt gcagagttgc tggagcagtt ccttttccca cgttcgacgc
    69301 atggaacctt gattgagaaa ttgtcagggg gtgagaaaaa acgtctttat ctcctcaaac
    69361 tgcttttgga aaaaccaaat gttcttcttt tagacgagcc aaccaatgac ctagatattg
    69421 caactttgac agtcttagag aatttcttgc aaggttttgc aggtcccgtt ttaacagtca
    69481 gtcacgaccg ctatttcttg gataaggtag cgaccaagat tctcgctttt gaggatggca
    69541 agattcgtcc tttctttggt cattacaccg actatcttga tgaaaaaact tttgaaacag
    69601 atatggccaa tcaagtgcaa aaggccgaaa aggaaaaagt ggtcaaggtt cgagaagaca
    69661 agaaacgcat gacctaccaa gaaaagcagg agtgggcaag tattgaaggt gatattgaag
    69721 ccttggaaaa acgtatcgct gctattgaag aggaaatgca ggctaacggc tctgactttg
    69781 gtaagctggc tactctccaa aaagaattgg atgagaaaaa tgaagcactc cttgaaaaat
    69841 acgaacgcta tgagtatctc agtgaatttg atagttaaga ctattcgaaa atcaaagtgc
    69901 aaactatgtc ggcttcacat tgccgactca agtacagcct gtgaccggct tcctaatttg
    69961 cactttgatt tttattgagt ataaaagaat agaaaaatcc cgtctcatga aaggatttct
    70021 ctattctttt ttggtttctt gatgaaagat attttgccag gtttcgtggc gacgccagat
    70081 actggtatgg atgataccat ctaactcata gcagatgagt ttggtttttt gactgatgga
    70141 agtaatttga atgtccttga tagcagaatt taactctttt ttggtcttat aagcctcttt
    70201 atccatctgc tctccatctt ggcgaatata gacaaaatca tcagtcaaga gttcttctag
    70261 ttggtttcct tggtcaatca attgttcacg cataagcaat tttttataga cattgtctaa
    70321 aatttcatcc tcagggatag gtgctggttc gatatggaca tcggtatcaa agacgccaaa
    70381 acgctcctcc agcatagact cgacctgatc cgcgatttca tggctttcaa aaacagacaa
    70441 gtcaggattc atctctagtg taatatccag gtagatgttg ctaccgtagg tgcgacctct
    70501 ttgcgatttg accttgctga ttttgggaat ttccatgata gccttttggt agtcctcgag
    70561 caggcggtcg tcaaagccat ctgaaagact aaaggaagat tcgatgaaga tatcataggc
    70621 agtcttcaag ataaagaaag tgatgatgat agcaaccagt ttatccacaa tcggataatt
    70681 gaaactacta gctaggatgg caatggcggt tccaagtgag gtaacagcgt cagaaagatt
    70741 gtccttagca gctgccttca gcgccttgga gttggatttc ttactgaggc gagtattgta
    70801 gagatagacc acaaacataa tcgctgcaga aatgattcct agagttgcac caagaggatc
    70861 aatgaccgtt tcttcccgac tgagaatctt ttgaatggta tctcttagaa catcgaaacc
    70921 gacatagaac atgatgatag aagtgatcaa gcttgccaaa tcttcaatct tccaatgacc
    70981 aaaacggtgg tcacggtctg caggctggcg cgccatccga atcccgatta agagggccac
    71041 atttccaatg atgtccgata cgttattaaa accatcggcc accaaactgg atgaatgaag
    71101 gagatgacca gctgctaatt tggctgcaga caagatcaaa taggtcgaaa tactgataat
    71161 ggctccacgc tcagctaact tgagatttga gatagattgc ttcattcaac ttcctttcta
    71221 gtcacatagc attctaccat tatactggtt ttcaaggaaa aattcaaata aggcagtttt
    71281 tactctttga aaactcccca aaatttggta taatggtact actcaaggga gtagctggca
    71341 gaaacctgtg atagtgtcgt cattccgaat tttatgctga aaagtatgct ttccggccct
    71401 atcttaaaca gcgagacttg ttatgattaa caggtctctt tttgtttgtc gtgaaaagat
    71461 atgacagaaa gagagtctgt tttgcacaca atgtcaagga ggagacacat gtcaaaagaa
    71521 caaaaacgcc aagcgtttta tactcagagc cctgaagagg tcttgcaggc tgtggatgcg
    71581 accgagcaag gtttgtcatc aagtgaggcg gaaaagcgcc ttgccgaatt tgggcacaat
    71641 gaactcgaag aaggcgagaa acgatcaatc ttggtcaaat tcatcgagca atttaaggat
    71701 ttgatgatta tcatcctagt tgcggcagca atcttgtcag tcgtgacttc tggtggggaa
    71761 gatatcgcag atgccattat catcctagct gtggttatca tcaacgctgc ctttggtgtt
    71821 taccaagaag gaaaagctga agaagctatt gaagccctca aatccatgtc tagtccagtt
    71881 gcccgcgttc ttcgtgatgg acacatggca gagattgact ctaaagaatt ggtaccaggc
    71941 gatatcgttg cccttgaagc aggtgacgtg gtaccagcgg acctacgttt gatagaagcc
    72001 aactctctta aaattgaaga agcagccttg acaggtgaat ctgtaccagt cgaaaaagac
    72061 ttgtcagtcg agcttgcgac agatgctggt attggtgacc gtgtcaacat ggccttccaa
    72121 aactcaaacg taacctatgg tcgtgggatg ggtgttgttg tcaatacagg tatgtacact
    72181 gaagttggtc atattgctgg tatgcttcaa gatgcggatg agactgatac accactcaaa
    72241 caaaacttga acaacctttc taaggtcttg acctatgcta tcttggtcat tgcccttgtt
    72301 acttttgtag tgggtgtctt cattcaaggg aaaaatccac ttggtgagtt gttgacttct
    72361 gttgcccttg ccgttgcagc cattccagaa ggacttcctg ctatcgttac catcgttctt
    72421 tctcttggta ctcaagtttt ggccaaacga cattccatcg ttcgtaagtt gccagcagtt
    72481 gaaacacttg gttcaactga aatcatcgct tctgataaga ctggtacgct gactatgaac
    72541 aagatgacag tcgaaaaagt cttctacgat gcggttctac atgactcagc tgatgatatt
    72601 gaactaggtc ttgaaatgcc actacttcgt tcagttctct tggccaatga tacgaaaatc
    72661 gatgtggaag gtaacttgat tggtgaccca accgaaacag cctttatcca atatgccttg
    72721 gacaagggct atgatgtcaa aggtttctta gagaaatatc ctcgtgtagc tgaattgcca
    72781 tttgactctg accgtaagct catgtcaaca gttcacccat tgccagatgg tcgtttcctt
    72841 gtagcagtca agggtgcgcc agaccaactc ttaaaacgtt gtcttcttcg tgataaggct
    72901 agggatattg ctccgattga tgagaaggtt acaaatctca ttcatacaaa caactctgaa
    72961 atggctcatc aagccttgcg tgtccttgca ggtgcttata agattattga cagcattcca
    73021 gaaaatctca cttctgaaga gcttgaaaat gatttaattt ttactggttt gattgggatg
    73081 attgaccctg aacgtcctga agccgctgag gctgttcgtg tggctaagga agcgggaatc
    73141 cgtccaatta tgattacagg tgaccaccaa gacacagcgg aagccattgc caaacgtttg
    73201 ggaatcattg acgcaaacga tacagaaggt cacattttaa ctggtgctga actcaatgaa
    73261 ctgtcagatg aagaatttga aaaagtcgtt ggtcaatact ctgtttatgc ccgtgtgtct
    73321 ccagaacaca aggttcgtat cgtcaaggct tggcaaaaac aaggtaaagt cgttgccatg
    73381 acaggtgacg gtgtcaatga cgcgccagct ctgaaaacag ccgatatcgg tatcggtatg
    73441 ggaatcactg gtacagaggt ttctaagggg gcttctgata tgattcttgc agatgataac
    73501 tttgcgacta ttatcgtcgc agtggaagaa ggacgtaagg tcttctcaaa cattcaaaag
    73561 actattcagt acctactttc tgctaatact gctgaagtat taaccatctt cctatcaacc
    73621 ttgtttggtt gggatgtctt acagccggtt catcttttgt ggatcaactt ggtaacggat
    73681 accttcccag ctatcgctct tggtgttgaa cctgcggaac ctggtgtcat gaatcataaa
    73741 ccacgtggac gcaaggcaag cttcttctca ggtggtgttt tgagttctat catttatcaa
    73801 ggtgtactcc aagcagctct tgttatgagt gtttatggcc ttgcgattgc ttacccagtt
    73861 catgtgggtg acaatcatgc tattcatgca gatgccctaa cgatggcttt tgcaaccctt
    73921 ggtttgattc agctcttcca tgcctacaat gtcaagtctg tctaccaatc catcttgaca
    73981 gttggcccat tcaagtctaa gacctttaac tggtccatct tggtatcctt tatccttctc
    74041 atggcaacaa tcgttgtaga accgcttgaa ggaatcttcc acgtaaccaa actagacttg
    74101 tcacaatggg gaattgttat ggctggaagc ttctcaatga ttatcatcgt cgaaatcgtt
    74161 aagtttattc aacgcaaact cggttttgac aagaatgcga tttaagggag gtttcggatg
    74221 tcagcatatt aattaccgac cgtatggcag gatgaagcta gtaatcaagg agcttttacg
    74281 gggctaaaca gaccaacagt aggtgcccgt ttcgaacaaa acttgccaaa aggagaacaa
    74341 gcttttcagc tttattcact gggaacacca aatggtgtga aggttactat cttattggaa
    74401 gaattactag aagctggttt taaggaagcg gcttacggct tgtataagat tgctatcatg
    74461 gatggggatc aattcggatc agactttgtg aagctcaatc caaattccaa gattccagcc
    74521 ttattggacc agtcaggtac tgaagatgta agagtctttg agtctgctca tattcttctt
    74581 taccttgctg agaaatttgg agccttttta ccaagtaatc ctgtggaaaa ggtagaagtt
    74641 ttgaattggc tattctggca agcaggtgca gcaccttttc taggtggggg atttggacat
    74701 ttcttcaatt atgctcctga aaaattggaa tatcctatta accgttttac aatggaagtg
    74761 aaacgccagt tggatttatt ggataaggaa ttggctcaga aaccttatat tgcaggcaat
    74821 gactatacga ttgcagatat tgctatctgg tcttggtatg gacagttagt tcaaggaaat
    74881 ctttaccaag gttctgcaaa attcttggat gcctcaagtt atcaaaatct agtaaaatgg
    74941 gcagaaaaaa ttgccaatcg tccagctgtt aagcgtggct tggaagtaac ttatacagaa
    75001 attaaatagc aaaaaagtca tcttcggatg gctttttgct acagttgagg gaaagggttt
    75061 gcagttatcg gcttttgtgc tataattgct ataatatagt aaaaagcaag aggagtgtga
    75121 ggaagtggaa aagaaaattg tgaaggatat cttattttta tctcaagtgt ctcagccggc
    75181 aagtcaggag gacctttatc ttgccagaga tttgcaggat acactcttag caaatcgtga
    75241 tacctgtgtt ggtctagctg ccaatatgat tggggtgcag aagcgcgtga ttatctttaa
    75301 tcttggcttg gttcccgtgg tcatgtttaa cccagtgctt ctgtcctttg aaggatccta
    75361 tgaggcagaa gaaggctgtt tgtccttggt aggtgtgaga tcaactaagt gttatgaaac
    75421 cataagggtt gcctatcgtg acagcaagtg gcaggaacag accattacct tgacaggctt
    75481 cccagctcag atttgccagc atgagctgga tcacttggaa ggacgaatca tttaggagga
    75541 aagcaaatga aacgaatagt ctttgaactt atttttatcg caacgacctg gtatatcttt
    75601 ttaccgcccc ttaacctgac cagctgggaa tttctcttct tcctctgtgg gcatttgtta
    75661 gttgtggcaa tcttatttgg ctttggcaag gggataaacc ttgtcaaaac ggttcatgtg
    75721 cgccacggta aggcggaagc tgccttaaat cttgagggtt tcaaaatcaa tcggttaggg
    75781 aaaattctgt tagcttcgat tggaggaatt cttctcttgg cagctttggt ttccttggta
    75841 acttctagca tgtttcaggc taaaaattat gccaatgtag tcacggttac ggaaaaagac
    75901 tttactgaat ttcctaagag tgacaccagt aaggttccta tcctagatag aagtactgct
    75961 gaaaaaattg gagaccgcta cttgggttcc ctaaccgata aggtgtcgca atacgtagcg
    76021 gcagatacct atacccaatt gacaattgat gggaaacctt atcgggtcac accactagaa
    76081 tatgcagacc ctatcaaatg gtttaacaat caagccaagg gaatcggtga gtatatcaag
    76141 gtggacatgg taactggaaa tgcggatttg gtggacttga agacaccaat caagtattca
    76201 gactcggagt attttaaccg tgatgtcaaa cgtcacctgc gcttgaagta cccgaccaaa
    76261 atctttaaaa ctccatcttt tgaggtggac gatgagggca atcctttcta tgtagcaacg
    76321 gtttaccaaa agcaatttgg acttgctgtt cctcgtcctg cttcagtcat tatcttggat
    76381 gctacaaatg gagaaaccaa ggaatacagc ttatcagatg ttccagaatg ggtggacagg
    76441 atctatccag cagaggaaac cattgagcaa attaactaca acggcaagta caaggacggt
    76501 ttcttgaatg ccatgatttc caagaaaaac gtgacccaga ctaccaaggg ctataattac
    76561 ttgtctatcg gtaatgacat ctatctctac acaggtgtga cgtcggctaa tgcggatgag
    76621 agtaatcttg gtttcatcct tgaaaatatg cgaacaggag aaatcactaa gtatagcttg
    76681 gcttctgcga cagaagaatc agcccgtgaa tcagcagaag gtgctgttca ggagaaatcc
    76741 tacaaagcaa ccttcccaat cctcatcaac ctcaatgaca agcctctcta catcatgggc
    76801 ttaaaggaca atgctggctt ggtcaaagag tacgccctgg tagacgcagt cgagtaccaa
    76861 aatgttatcg ttgctactac agtggaagag atgctcagca agtatgccaa taaaaacgac
    76921 cttgaaattg acaatgcaac gacagaaagc atcaagggag tagtagcaga cctcaaatca
    76981 gctgttatca agggagacac tgtctacttc tttaaagttg atggcaagat atacaaggtc
    77041 aaggcttcag tatccgatga ccttccttac cttgaaaatg gtaaaacctt cgaaggtcaa
    77101 gtaggaaaag acaattatct caagaccttt aagctacggt aaaaataggt tttttcagaa
    77161 agtatatgtt ataatagagt aaattaagac taatggagga caaagaaatg ggtttttatt
    77221 tgatggttgc ttcaatgcta ctcggactgc tcgctttgaa gataggtttt tctcagttca
    77281 aggagaaaaa agataaattc ttatctatct taacaagttt agctggcaca gcccttgttc
    77341 tcgtggctgt ctggttagga tggcccaaat aaatagaaaa acctcggtca aaccgaggtt
    77401 tttcaaatga atttcttggt tgtggctaaa aaatatgcta cactatcaat atgaaaattt
    77461 taatcccaac agcaaaagaa atgaacacag acttgccaag tatcgaggca attcctttaa
    77521 aaccagaaag tcaggccgtg cttgatgcct tggctctcta ttctgccagt caattggaga
    77581 gtttctacaa ggtatcagct gagaaagcgg cggaagaatt tcaaaatatc caagctttga
    77641 aaaggcaaac tgctcaacac tatccagcct tgaaactttt tgatgggctt atgtaccgca
    77701 acattaagag agataagctg accgaggcgg aacaagatta tcttgaaaat catgtcttca
    77761 ttacctcggc tttgtacggt gttgttccag ccttgtcacc catggctcct caccgtttgg
    77821 attttttgat gaaattaaaa gtcgttggta agactttgaa gagccattgg aaggcagtct
    77881 atgatgaagc tctgaagaag gaagaagtga ttttctctct cttgtcatca gagtttgaga
    77941 ctgtattttc taaggaaatc agagcaaaga tggtgacctt caaattcatg gaggatagag
    78001 ggggtcagct gaagattcac tcaactatct ccaagaaggc gcgcggggcc tttctaacag
    78061 ctttaataga aaatcaagta caaactgtgg gggaagcacg tcgcttgaac tttgctggat
    78121 ttgtttaccg agaagatttg tcacaaccac agggattggt ttttgtaaag gaagtataga
    78181 aatcagatat tttgtatttg gcaatatgta tcatcagcta ttttagttta taaatgagaa
    78241 aaaagcgaac aagctagtct tctgagtgtc agaaaagtag tcttgttcgc ttttattatg
    78301 ttatactctt cgaaaatcta aaatctcttc aagccacgtc agcgtcgcct taccgtatat
    78361 atgttactga cttcgtcagt tctatctaca acctcaaagc agtgctttga gtagcttgcg
    78421 gctagcttcc tagtttgctc tttgattttc attgagtatt agtttataaa tgagaaaaaa
    78481 gcgaacaagc taatcttctg agtgtcagaa aagcagtctt gttcgctttt attatgttag
    78541 tttagttact tgatagcatt gaccaagtct tgagcttgtt tgtcaagtga gtttaggaca
    78601 gtttcttcaa gaaccaattt cccgtctgcc caggcagagt cattaacacg tgcagcagtg
    78661 aaatcgccaa cgacttgtgt acggataaat ggcaagaggt ctttgtagat agcgaagagt
    78721 tgatcgtgcc ctgcattggc tacagatgat acggtgacaa acttgtcttg aagggcagaa
    78781 gcaccacgtg tatcagacaa gtcaagggca cgagatagcc agtccagcaa gttcttcact
    78841 gtaccaggga tagagaagtt gtagactgga gagaaaatcc agatagcatc cgcaacgaga
    78901 actgcttcac gagcagcagc tacagctgga tgtgttggaa cttccaaatc ttggctgaag
    78961 agaggaaggg ctgaataatc aaggtagcta acttccgctt taccagcaag tgctttctca
    79021 gcttcgagcg ccatttggtg gttgaaagaa ccttgacgta gtgatccgac gataaataat
    79081 acttttttag acatgatgtg tctccttttt cttcaaattt cgagaactct ctcgttgtta
    79141 taaaatatat tacaacaaaa caaaagaact tgcaagaaat ttgctcagag tttatttgaa
    79201 aattgtaaaa tttcggaaac tctagtcatt tgtgactgaa aaagtaagaa ctgtttcact
    79261 ttcaaaatcg gttttgtttg aagggagaaa tagaattggt tgctcaaagc acagctttga
    79321 ggttgcagat aaagctgacg tggtttgaag agattttcga agagtattct tatattcact
    79381 tgtaataaag cttaatagat ggtaaaatag acgagtgaaa aaaagacaaa acaaagcaaa
    79441 aaataatcta ctgtggcagt atggtctagg gatgacgatt ttgtttgtgg ttatcagtgc
    79501 ttcctttctg tatatggttt ctcttagcat gaaaccctat caaacagcta aaagtgaagg
    79561 agaaaaatta gctcagcagt atgcaggatt agagcaggcc gatcaggttg atttatacaa
    79621 tggcttggaa tcttattaca gcgttcttgg tcgtaataaa cagcaagaag cacttgctgt
    79681 tctgattgga aaagatgatc ataagattta cgtttatcag ctaaatcagg gtgtttcaca
    79741 agaaaaagca gaaacggttt ctaaggaaaa gggagctggc gaaattgaca agattatctt
    79801 tggtcgttat caagataagc caatctggga agtcaagtca ggatctgatt tttatctagt
    79861 agattttgaa acaggagcat tggtcaacaa ggagggccta tgaaattatc caaccgtgtt
    79921 ttagaaatgg aagaaagtgt gactttggct gctggagccc gtgccaaagc actgaaggct
    79981 gagggcagag atattttgtc tctaaccttg ggtgagccag atttcactac tcccaaaaat
    80041 atccaagatg ccgccattgc atcgattcga gatgggcgtg cttcttttta tacagtaacc
    80101 tcaggtctgc cagagcttaa ggcggcggtc aatagctact ttgagcgctt ttacggctat
    80161 tctgtagcgt caaatcaagt gacagtcgct gcgggagcca aatattctct ctataccttc
    80221 tttatggctg tggtcaatcc aggtgatgaa gtcatcatcc caaccccata ctgggttagc
    80281 tatggagatc aggtcaagat ggcagaaggc gttcccgtct ttgtttctgc taaggaagac
    80341 aatcacttta aggtgaccgt ggagcagtta gaagcagctc gcactgacaa gaccaaggtt
    80401 ttggtgctga attcgccatc taatcccaca ggtatgattt acacccgtga ggaactcttg
    80461 gcaattggaa actgggctgt agaaaatgat attctcatcc tagcagatga tatctatggc
    80521 cgcttggttt ataatggtca tgagttcaca ccgatttcta gcctatcgga agcgattcgc
    80581 aagcaaacag tggtcatcaa tggtgtgtct aaaacctatg ccatgactgg ttggcggatt
    80641 ggttatgccg ttggagaagc agacattatc gctgccatgt ccaagattgc aggtcaaaca
    80701 acttcgaatc cgtcagcagt agcccaatat gcagcagttg aggctctatc aggtgagcaa
    80761 gatactgtag aaagcatgcg tcaggccttt gaggaacgtc ttaataccat ctatcccctc
    80821 cttgcagagg tgccaggatt tgaagtggtc aaaccacaag gggccttcta tctcttccca
    80881 aatgtcaaaa aggccatgga gatgaaaggc tacacggatg tgacagactt tacaactgtt
    80941 atcttagaag aagccgaagt ggccttggta acaggagctg gatttggagc accagaaaat
    81001 gtccgcctca gctatgcgac agacctagac acgcttaaag aagcagtcga acgcttgaaa
    81061 gcatttatgg gtagtgagaa taattgatca ttttgagatt aaggtaaagg atttacaaat
    81121 tttagaagga ttttatagga gttttctcgc tcctttggac tataaattgg cttttaagac
    81181 tagttctcta attagttttc tatccccgaa cagccctcat cctggtggtg atttttggct
    81241 gactcaggga acacaagatc ctgttcattt tgctttttta gcagaaaata aggaagaagt
    81301 tcaggcttgt tatgaggctg gcttagaggc aggtgggcga gacaatgggg ctcctggtta
    81361 tcgcagtgag catccgattt actatgctgc ttttatgatt gacctggatg ggaacaatat
    81421 agaggtggtt tgccataaag aataaaaaag aaaaggaaaa ataatgacaa aacgtgtaac
    81481 gattattgac gtaaaagact atgttggtca ggaagtgacg attggcgctt gggttgccaa
    81541 caaatcagga aaagggaaaa tcgccttctt acaattgcgt gatggaacag ccttctttca
    81601 aggtgtggct tttaaaccaa actttgtcga aaaatttggt gaagaagtgg gacttgagaa
    81661 gtttgatgtt atcaaacgct tgagccaaga aacgtctgtt tatgtgacag gtattgtcaa
    81721 agaggacgaa cgttctaaat ttggctatga gttggacatc acagacatcg aagtgatcgg
    81781 tgaatctcaa gactacccaa tcacaccaaa agaacacgga acagactttt tgatggataa
    81841 ccgtcacttg tggctacgct ctcgtaagca agtagctgtg ttgcaaatcc gtaacgctat
    81901 tatctatgca acttatgagt tctttgacaa gaacggtttt atgaagtttg acagcccaat
    81961 tctttcagga aatgcggcag aagattctac agaactcttt gaaactgact acttcggaac
    82021 gccagcctac ttgagccaat caggtcagct ttacctagaa gcaggggcta tggctcttgg
    82081 tcgtgtcttt gactttggtc cagtttttcg tgctgaaaaa tcaaaaacac gccgtcactt
    82141 gactgagttc tggatgatgg atgctgagta ctcatacttg acacatgatg agtcgcttga
    82201 cttgcaagaa gcttatgtga aagctcttct acaaggtgtt cttgaccgcg cgcctcaagc
    82261 cttggaaacc ttggaacgtg atacagaact cttgaaacgc tacattgcag agccattcaa
    82321 acgtatcact tatgatcaag ccattgacct cttgcaagag catgaaaatg atgaagacgc
    82381 tgattacgag catcttgagc atggtgatga ctttggttcg ccacatgaaa cttggatctc
    82441 aaatcacttt ggtgtaccaa cttttgtcat gaactatcca gcagccatca aggccttcta
    82501 catgaaacca gttcctggaa atccagagcg cgtgctttgt gcagacttgc ttgctccaga
    82561 aggttacgga gaaatcatcg gtgggtctat gcgtgaggaa gactacgatg cccttgtcgc
    82621 taagatggat gaacttggca tggatcgtac agagtacgaa ttttaccttg accttcgtaa
    82681 atacggtaca gttccacacg gtggatttgg tatcggtatc gaacgtatgg taaccttcgc
    82741 agcaggaaca aaacacatcc gtgaagccat tccattccca cgtatgttgc atcgtatcaa
    82801 accgtaagaa taggaaaacg tccatgtggt gttttttcga attccagagt ttttacttgc
    82861 gtaaaaaatt tttttctagt ataatagttc attgtgagcg aacctcactt accccttgca
    82921 aagtcttggg gtcattagac caaaaggagg aacatatcaa tggctaaata cgaaattctt
    82981 tatatcattc gtccaaacat tgaagaagaa gctaaaaacg ctttggtagc acgttttgac
    83041 tctattttga ctgacaacgg tgcaactgtt gttgaatcaa aaacttggga aaaacgtcgt
    83101 cttgcatacg aaatcaaaga tttccgtgaa ggactttacc acatcgttaa cgttgaagca
    83161 aacgacgacg tagctcttaa agagtttgac cgtctttcaa aaatcaacgc tgacattctt
    83221 cgtcacatga tcgtcaaaat tgacgcgtaa gaaggtaaac tatgattaac aatgttgtac
    83281 ttgtggggcg tatgacacgt gacgctgagt tgcgttatac cccatcaaat gtagcagttg
    83341 cgacttttac tcttgcagta aaccgtacat ttaagagtca aaatggcgaa cgtgaggctg
    83401 attttatcaa tgtcgttatg tggcgccaac aggctgaaaa ccttgctaat tgggctaaaa
    83461 aaggctcact tatcggggtg acaggccgta tccagactcg tagttacgat aaccagcaag
    83521 gacaacgtgt ctacgtgaca gaggtcgtgg ctgagaattt ccaaatgttg gaaagccgta
    83581 gtgtgcgtga aggtcacaca gttggtgcct attctgcacc aactgcaaac tattcagcgc
    83641 ctacaaattc agtaccagac ttttcacgtg atgaaaatcc atttggagca actaatccat
    83701 tggatatttc agatgatgat ttaccattct aatggacaac taaaattata aaggagaaaa
    83761 aacatggctc aacaacgtcg tggcggattc aaacgccgta aaaaagttga ttacatcgca
    83821 gcaaacaaaa ttgaatatgt tgattacaaa gatactgagc ttcttagccg tttcgtttca
    83881 gaacgtggga aaatccttcc tcgtcgtgta acaggaactt cagctaaaaa ccaacgtaaa
    83941 gtaacaacag ctatcaaacg cgctcgcgta atggctttga tgcctttcgt aaacgaagat
    84001 taaagaaaag
//
LOCUS       DAVDZK010000003        80691 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVDZK010000003 DAVDZK010000000
VERSION     DAVDZK010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 80691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80691
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.003"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(506..1696)
                     /locus_tag="VUX16_000238"
     CDS             complement(506..1696)
                     /locus_tag="VUX16_000238"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET8123293.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(1911..3254)
                     /locus_tag="VUX16_000239"
     CDS             complement(1911..3254)
                     /locus_tag="VUX16_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET8123294.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(3394..4209)
                     /locus_tag="VUX16_000240"
     CDS             complement(3394..4209)
                     /locus_tag="VUX16_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET8123295.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPL
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            complement(4261..6441)
                     /locus_tag="VUX16_000241"
     CDS             complement(4261..6441)
                     /locus_tag="VUX16_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET8123296.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPNQMTEV
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(6727..7653)
                     /locus_tag="VUX16_000242"
     CDS             complement(6727..7653)
                     /locus_tag="VUX16_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8123297.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEEAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(7646..8338)
                     /gene="ftsE"
                     /locus_tag="VUX16_000243"
     CDS             complement(7646..8338)
                     /gene="ftsE"
                     /locus_tag="VUX16_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET8123298.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(8356..9451)
                     /gene="prfB"
                     /locus_tag="VUX16_000244"
     CDS             complement(join(8356..9378,9380..9451))
                     /gene="prfB"
                     /locus_tag="VUX16_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET8123299.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIVILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(9559..10215)
                     /locus_tag="VUX16_000245"
     CDS             complement(9559..10215)
                     /locus_tag="VUX16_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET8123300.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(10523..11233)
                     /locus_tag="VUX16_000246"
     CDS             complement(10523..11233)
                     /locus_tag="VUX16_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123301.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVASGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(11233..11997)
                     /locus_tag="VUX16_000247"
     CDS             complement(11233..11997)
                     /locus_tag="VUX16_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123302.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(11997..12953)
                     /locus_tag="VUX16_000248"
     CDS             complement(11997..12953)
                     /locus_tag="VUX16_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET8123303.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILTVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVTS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(12957..13826)
                     /locus_tag="VUX16_000249"
     CDS             complement(12957..13826)
                     /locus_tag="VUX16_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET8123304.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGIVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(14094..15254)
                     /locus_tag="VUX16_000250"
     CDS             complement(14094..15254)
                     /locus_tag="VUX16_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET8123305.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(15356..15604)
                     /locus_tag="VUX16_000251"
     CDS             complement(15356..15604)
                     /locus_tag="VUX16_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET8123306.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(15683..16273)
                     /gene="clpP"
                     /locus_tag="VUX16_000252"
     CDS             complement(15683..16273)
                     /gene="clpP"
                     /locus_tag="VUX16_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET8123307.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(16447..17076)
                     /gene="upp"
                     /locus_tag="VUX16_000253"
     CDS             complement(16447..17076)
                     /gene="upp"
                     /locus_tag="VUX16_000253"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET8123308.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(17165..17632)
                     /locus_tag="VUX16_000254"
     CDS             complement(17165..17632)
                     /locus_tag="VUX16_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET8123309.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(17651..18208)
                     /locus_tag="VUX16_000255"
     CDS             complement(17651..18208)
                     /locus_tag="VUX16_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET8123310.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            18333..19178
                     /locus_tag="VUX16_000256"
     CDS             18333..19178
                     /locus_tag="VUX16_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET8123311.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            19237..20412
                     /locus_tag="VUX16_000257"
     CDS             19237..20412
                     /locus_tag="VUX16_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET8123312.1"
                     /translation="MKHFDTIVIGGGPAGMMSTISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTIIELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVNGGEVLSLDVLPQLSEKNLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            20432..20887
                     /locus_tag="VUX16_000258"
     CDS             20432..20887
                     /locus_tag="VUX16_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET8123313.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDCRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            20996..22286
                     /locus_tag="VUX16_000259"
                     /pseudo
     CDS             20996..22286
                     /locus_tag="VUX16_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937360.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(22426..23175)
                     /locus_tag="VUX16_000260"
     CDS             complement(22426..23175)
                     /locus_tag="VUX16_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET8123314.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            23280..23501
                     /locus_tag="VUX16_000261"
     CDS             23280..23501
                     /locus_tag="VUX16_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HET8123315.1"
                     /translation="MIFLTDLRKHDRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGWPSGLVPFGSFPT"
     gene            23498..24749
                     /locus_tag="VUX16_000262"
                     /pseudo
     CDS             23498..24749
                     /locus_tag="VUX16_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851261.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(24771..25715)
                     /gene="manA"
                     /locus_tag="VUX16_000263"
     CDS             complement(24771..25715)
                     /gene="manA"
                     /locus_tag="VUX16_000263"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET8123316.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDTLLTKVPVKAG
                     DFFYVPSGTMHAIGPGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADNLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLFSILAGQGQL
                     TVDGKNYPIQKGSHFIVLSDVESWTLEGQDLELIVSHP"
     gene            complement(25836..26133)
                     /locus_tag="VUX16_000264"
                     /pseudo
     CDS             complement(25836..26133)
                     /locus_tag="VUX16_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380709.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            26198..27305
                     /locus_tag="VUX16_000265"
                     /pseudo
     CDS             26198..27305
                     /locus_tag="VUX16_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(27422..27769)
                     /locus_tag="VUX16_000266"
     CDS             complement(27422..27769)
                     /locus_tag="VUX16_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET8123317.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVK
                     GPAGLVLDFYRMK"
     gene            complement(27880..29655)
                     /gene="spxB"
                     /locus_tag="VUX16_000267"
     CDS             complement(27880..29655)
                     /gene="spxB"
                     /locus_tag="VUX16_000267"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET8123318.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(29862..32105)
                     /locus_tag="VUX16_000268"
     CDS             complement(29862..32105)
                     /locus_tag="VUX16_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET8123319.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEAIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDETEVLGLATSLEEASQHPLAEAIVKRASEAGLEFHTVENFQALHGKGV
                     SGQINGKQVLLGNAKMLDGMDISSIYQEKLEQLEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLKTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKVHEIHKL
                     QAAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(32115..32486)
                     /locus_tag="VUX16_000269"
     CDS             complement(32115..32486)
                     /locus_tag="VUX16_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET8123320.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYAPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(32497..32892)
                     /locus_tag="VUX16_000270"
     CDS             complement(32497..32892)
                     /locus_tag="VUX16_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET8123321.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      33076..33174
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            33258..34049
                     /gene="thiD"
                     /locus_tag="VUX16_000271"
     CDS             33258..34049
                     /gene="thiD"
                     /locus_tag="VUX16_000271"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET8123322.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDTPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(34258..34890)
                     /locus_tag="VUX16_000272"
     CDS             complement(34258..34890)
                     /locus_tag="VUX16_000272"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET8123323.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMDTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(34883..35686)
                     /locus_tag="VUX16_000273"
     CDS             complement(34883..35686)
                     /locus_tag="VUX16_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET8123324.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVSASPIRKG
                     LVRDLLDYSPTILKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSILRRDENWLDTIKGEVYE"
     gene            complement(35686..36210)
                     /gene="thiW"
                     /locus_tag="VUX16_000274"
     CDS             complement(35686..36210)
                     /gene="thiW"
                     /locus_tag="VUX16_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET8123325.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(36215..36907)
                     /gene="tenA"
                     /locus_tag="VUX16_000275"
     CDS             complement(36215..36907)
                     /gene="tenA"
                     /locus_tag="VUX16_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET8123326.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(36918..37568)
                     /locus_tag="VUX16_000276"
     CDS             complement(36918..37568)
                     /locus_tag="VUX16_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET8123327.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(37570..38955)
                     /locus_tag="VUX16_000277"
     CDS             complement(37570..38955)
                     /locus_tag="VUX16_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123328.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(38956..39516)
                     /locus_tag="VUX16_000278"
     CDS             complement(38956..39516)
                     /locus_tag="VUX16_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET8123329.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(39779..39867)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(40090..40719)
                     /locus_tag="VUX16_000279"
     CDS             complement(40090..40719)
                     /locus_tag="VUX16_000279"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET8123330.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(40721..41503)
                     /gene="thiM"
                     /locus_tag="VUX16_000280"
     CDS             complement(40721..41503)
                     /gene="thiM"
                     /locus_tag="VUX16_000280"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET8123331.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(41730..42398)
                     /locus_tag="VUX16_000281"
     CDS             complement(41730..42398)
                     /locus_tag="VUX16_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET8123332.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(42613..42701)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42955..44091)
                     /gene="lctO"
                     /locus_tag="VUX16_000282"
     CDS             complement(42955..44091)
                     /gene="lctO"
                     /locus_tag="VUX16_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET8123333.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(44715..46205)
                     /gene="lysS"
                     /locus_tag="VUX16_000283"
     CDS             complement(44715..46205)
                     /gene="lysS"
                     /locus_tag="VUX16_000283"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET8123334.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            46390..46770
                     /locus_tag="VUX16_000284"
                     /pseudo
     CDS             46390..46770
                     /locus_tag="VUX16_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            complement(46857..47504)
                     /locus_tag="VUX16_000285"
     CDS             complement(46857..47504)
                     /locus_tag="VUX16_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123335.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(47501..48199)
                     /locus_tag="VUX16_000286"
     CDS             complement(47501..48199)
                     /locus_tag="VUX16_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123336.1"
                     /translation="MGKLSSHMWRLNQIIYAKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLVVVYRRRASDFFLEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(48209..48961)
                     /locus_tag="VUX16_000287"
     CDS             complement(48209..48961)
                     /locus_tag="VUX16_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123337.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFHLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(48961..49725)
                     /locus_tag="VUX16_000288"
     CDS             complement(48961..49725)
                     /locus_tag="VUX16_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123338.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEV
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESYFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(49821..50224)
                     /locus_tag="VUX16_000289"
                     /pseudo
     CDS             complement(49821..50224)
                     /locus_tag="VUX16_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(50404..51036)
                     /locus_tag="VUX16_000290"
     CDS             complement(50404..51036)
                     /locus_tag="VUX16_000290"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET8123339.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(51070..51771)
                     /gene="pyrF"
                     /locus_tag="VUX16_000291"
     CDS             complement(51070..51771)
                     /gene="pyrF"
                     /locus_tag="VUX16_000291"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET8123340.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            52090..52182
                     /locus_tag="VUX16_000292"
                     /pseudo
     CDS             52090..52182
                     /locus_tag="VUX16_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(52505..53218)
                     /locus_tag="VUX16_000293"
     CDS             complement(52505..53218)
                     /locus_tag="VUX16_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8123341.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEEFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(53211..54044)
                     /locus_tag="VUX16_000294"
     CDS             complement(53211..54044)
                     /locus_tag="VUX16_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123342.1"
                     /translation="MIEVSHLSKSFGDKIALNDISFTVKEGQIFGFLGPSGSGKTTTI
                     NILTGQLLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSKFY
                     NISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSGLD
                     PTTSRTIHELILELKTAGTTIFLTTHDMNEASLLCDYVALLNKGKLVEQGAPSELIQR
                     YNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGKLN
                     A"
     gene            complement(54254..55402)
                     /locus_tag="VUX16_000295"
     CDS             complement(54254..55402)
                     /locus_tag="VUX16_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HET8123343.1"
                     /translation="MDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLGAGALGCYISLSL
                     SMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSQKIHKYNSDVQVVPISI
                     KVSSVEELENIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLII
                     DNIYIPTIGSCFACRNINKDINKYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCY
                     NEILIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLL
                     SGGVAFLSAIGQFTVIETQLIVLFLGIIFAIYYAYYNKNIQTSLENIVWLFSSFEILF
                     LLVNFRTFIQLPVDIFISMIIFLMLWIFIMLGIVCLSYYITLLFSKEA"
     gene            complement(55439..55627)
                     /locus_tag="VUX16_000296"
                     /pseudo
     CDS             complement(55439..55627)
                     /locus_tag="VUX16_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828969.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(55611..56618)
                     /locus_tag="VUX16_000297"
     CDS             complement(55611..56618)
                     /locus_tag="VUX16_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HET8123344.1"
                     /translation="MRIVDKIKILPTPYEGQYHLYIPSSKKHVLVGKQEKKWLEQLIG
                     QEFTISDLLVLVGKKYYLRFYIVLSKMGLIDSMKSRKKINIFKISWDFNITLSEKLNY
                     KRFNKNFEKILFGIFPLALILQCFIMYIYRADILTNFQNFPITLNILLFWLLVVIISA
                     TIHEFSHAIIANNYQIEIPNCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIAS
                     NSILSLTGLLVLLFTSYKLLGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNL
                     NFQYIVQLLIAFVIIYFPLSQLLQFLTPNIIVRSIGGVVVSILLSILYMRGRTKYVLR
                     K"
     gene            complement(57200..58399)
                     /gene="divIB"
                     /locus_tag="VUX16_000298"
     CDS             complement(57200..58399)
                     /gene="divIB"
                     /locus_tag="VUX16_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET8123345.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(58409..59467)
                     /locus_tag="VUX16_000299"
     CDS             complement(58409..59467)
                     /locus_tag="VUX16_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET8123346.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(59471..60823)
                     /locus_tag="VUX16_000300"
     CDS             complement(59471..60823)
                     /locus_tag="VUX16_000300"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET8123347.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGTIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAVNEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(60927..61568)
                     /locus_tag="VUX16_000301"
     CDS             complement(60927..61568)
                     /locus_tag="VUX16_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123348.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(61570..63591)
                     /locus_tag="VUX16_000302"
     CDS             complement(61570..63591)
                     /locus_tag="VUX16_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET8123349.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(63674..63973)
                     /locus_tag="VUX16_000303"
     CDS             complement(63674..63973)
                     /locus_tag="VUX16_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET8123350.1"
                     /translation="MKTKKHRLLALVLISSFTLLGAASTAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWDGHSDKGEAPAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(64337..64591)
                     /locus_tag="VUX16_000304"
     CDS             complement(64337..64591)
                     /locus_tag="VUX16_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET8123351.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(64611..66452)
                     /gene="typA"
                     /locus_tag="VUX16_000305"
     CDS             complement(64611..66452)
                     /gene="typA"
                     /locus_tag="VUX16_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET8123352.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            66614..67339
                     /locus_tag="VUX16_000306"
     CDS             66614..67339
                     /locus_tag="VUX16_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HET8123353.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDSCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(67379..67606)
                     /locus_tag="VUX16_000307"
     CDS             complement(67379..67606)
                     /locus_tag="VUX16_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123354.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(67695..68075)
                     /locus_tag="VUX16_000308"
     CDS             complement(67695..68075)
                     /locus_tag="VUX16_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET8123355.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNKEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(68075..68344)
                     /locus_tag="VUX16_000309"
     CDS             complement(68075..68344)
                     /locus_tag="VUX16_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET8123356.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            68408..69316
                     /locus_tag="VUX16_000310"
     CDS             68408..69316
                     /locus_tag="VUX16_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET8123357.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLSHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(69370..70125)
                     /locus_tag="VUX16_000311"
     CDS             complement(69370..70125)
                     /locus_tag="VUX16_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET8123358.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(70146..71075)
                     /locus_tag="VUX16_000312"
     CDS             complement(70146..71075)
                     /locus_tag="VUX16_000312"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET8123359.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCAGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(71090..71713)
                     /locus_tag="VUX16_000313"
     CDS             complement(71090..71713)
                     /locus_tag="VUX16_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET8123360.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(71706..72944)
                     /gene="hflX"
                     /locus_tag="VUX16_000314"
     CDS             complement(71706..72944)
                     /gene="hflX"
                     /locus_tag="VUX16_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET8123361.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(72937..73821)
                     /gene="miaA"
                     /locus_tag="VUX16_000315"
     CDS             complement(72937..73821)
                     /gene="miaA"
                     /locus_tag="VUX16_000315"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET8123362.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSETKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            73942..74112
                     /locus_tag="VUX16_000316"
     CDS             73942..74112
                     /locus_tag="VUX16_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET8123363.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(74160..74999)
                     /locus_tag="VUX16_000317"
     CDS             complement(74160..74999)
                     /locus_tag="VUX16_000317"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET8123364.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLIQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(75096..76055)
                     /locus_tag="VUX16_000318"
     CDS             complement(75096..76055)
                     /locus_tag="VUX16_000318"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET8123365.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(76182..77180)
                     /locus_tag="VUX16_000319"
     CDS             complement(76182..77180)
                     /locus_tag="VUX16_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET8123366.1"
                     /translation="MNKRLFLKMSLATLPVLALFSQPVLAEENIHFSSCKEAWGNGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTATQINTSSATTSGWVKQDGA
                     WYYFDGNGNPVKNAWQGSYYLKADGKMAQSEWVYDSSYQAWYYLKSDGSYAYSTWQGN
                     YYLKSDGKMAQSEWAYDSSYQAWYYLKSDGSYAYSTWQGNYYLKSDGKMAKGEWIYDS
                     SYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGDDGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(77230..77847)
                     /locus_tag="VUX16_000320"
     CDS             complement(77230..77847)
                     /locus_tag="VUX16_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET8123367.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSSYQKA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALVLSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMIGVSEELKTLDLTDIAGICPYPTLLICGSKDRPNL
                     SSMKTLHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKIRSFLELLK"
     gene            complement(77848..79569)
                     /gene="pabB"
                     /locus_tag="VUX16_000321"
     CDS             complement(77848..79569)
                     /gene="pabB"
                     /locus_tag="VUX16_000321"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET8123368.1"
                     /translation="MHRKTVIDFRALGERYTFTQPIKEIKTRNVAEVADLLAQVESYQ
                     KQGYYVVGYVSYEAAPAFEEKFAVHKAPLLGEYLLYFTVHDSVETSPIPLTYDEVDLP
                     SDWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVIEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNGRELATRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVEHLCQVEQYSTVWQMTSTIKSRLRADVDLI
                     TIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYQEVHQKAAVLYRKQARFQLITTGKISQKNLLFEA
                     QHLERLRKASRYFASPFDAEDLKQKIKEECQDCDVNQDYRLRISLSKSGEIEVNRQVL
                     TPLSRTFCYAQLCLQEANLQQAFTYFKTSHRPHLGLRKQEIIYHNAAGELLETSIGNL
                     VLKISGRLYTPPIELGILPGIYRQHLLERGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELILQEN"
     gene            79756..>80691
                     /locus_tag="VUX16_000322"
     CDS             79756..>80691
                     /locus_tag="VUX16_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET8123369.1"
                     /translation="MEQLHFITKLLDIKDPNIQFMDIINMDTHKEIIAKLDYDAPSCP
                     NCGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYQCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKASMTDIAHQLSISTSTVIRKLNDFRFKHDFSYLPEIMSWDEYS
                     FTKGKMSFIAQDFKKLNIIAVLEGRTQAIIRNHFLRYDRAIRCQVKIITMDMFSPYYA
                     LAKQIFPCAKIVLDRFHIVQHLSRAMSRVRVQIMKQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKLLTYSEDLKHH"
BASE COUNT        24439 a        17420 c        14521 g        24311 t
ORIGIN      
        1 tttaattcta ggtttactag attctgtggt tctatctatt tattcggaaa agaaagtcta
       61 gtacagaagt catgctatgg aaacagctag tgtattagaa gtttgaacaa ggcttgggta
      121 acagactttt gaatgaagtc caagcaacaa ggagaaatct ccaccatgag tccattccat
      181 gactctgttg ctctagaaaa ccttgcaata gtcaagtgat aacgaataaa actttggatt
      241 gaaatatccc caagattatc tattacgagg agaaatctta acctttatca tttttaaaga
      301 aatatagtaa aatgaaacaa gaacaggaga aatcgatcag gacagtcaaa ttgattgcta
      361 acaatgtttt agaagttgag gtgtactatt ctagtttcaa tctactatac atgtaaatct
      421 ctactttcgc aaaatggatt ttcagaacag tatcccagta tagttaaaaa ctataaaaaa
      481 gagaggacgt tcccctctta aaatcttatt ttactgcttc tttcaaagca tctaccttat
      541 ccaaacgttc ccatggaaga tcaatatctg tacgtcccat gtgaccgtaa gccgatgttt
      601 gacggtaaat tggacgcttg aggtccagca tttggataat ccctgcaggg cgaaggtcaa
      661 agatttgacg agccgctttt tcaagttgac tttcagctac tgttcctgta ccgaaagtat
      721 cgatacgaac agaaacaggt tgcgcaacac cgatagcata ggccaactgc acttctgcct
      781 tcttagcaag gcctgctgca acgatattct tggcaatata gcgagccgca taagaggctg
      841 aacgatccac cttagtcgca tctttaccag agaaggcacc accaccatga cgagagtagc
      901 caccataagt atctacaata atcttacgac cagtcaaacc tgagtcccct tgaggaccac
      961 cgattacaaa acgacctgtc ggattgataa agaattttgt cttatcatca agataagaag
     1021 atggaataac ttctttgatg accttgtcaa tcacatcttg atggatttgt tcattagtgg
     1081 cctctggatc atgctgagta gaaataacga ctgtatctac acgtaccgga cggtcatttt
     1141 catcgtactc aactgtaact tgtgattttg catctggacg gagatagcta atttctccag
     1201 acttacgaag ttctgccaga cgacgaacca atttatgact gagtgcaatt ggcaatggca
     1261 taagctcttc tgtttcatct actgcaaatc caaacatgag cccttggtca cctgctccaa
     1321 tcaagtccag tggatcttga tcagcatttc cacgaacctc caaggcttcg ttaacacctt
     1381 gagcgatgtc aggagattgt tccaccaaag atgggtgtac tcccaccgtc tcagcagaaa
     1441 atccatattc tgtattggta taaccaatct ctgcaatggt atcacgaacc acacggttaa
     1501 tatccacata ggcatttgta gaaatttcac caaaaacgtg gacagaacca gtatatacag
     1561 ctgtttcagc agcaacgtgc gcctctggat cctttgctaa aatagcatcc aaaatcgcat
     1621 ctgaaatttg gtctgcaatc ttatccggat gcccctcaga tacagattca gacgtgaata
     1681 atttacgttc tgacataaaa atgtcccccc ttaaaaaata ttgttataga gttacaaagt
     1741 actgatagga aaactcttcg taataaatac ctaccatctt atcgggacta tataacttta
     1801 tcattatagc atttttaatc gcaatttgca gtctttaatg tagtgtttcg gtttagatag
     1861 ttcgttctca taaagcaaaa agttggagct cagtactcca acaatttcta ttaaaatgtt
     1921 tgacgtttag ctttacgctc tgcacgaccg cgagcgcgat tttcagcacg cttggtttta
     1981 cggcgctttt catcaaccgc ccattgaatt ttcttcttat aacccggttt gacttttttc
     2041 tttttctttt taaccaaacc aatcatttcg atatcaagtt tatcttgttt tttctcacgg
     2101 ttggcacgac gatcacggtc ataggtatct tgaaattccc cgtctttgac catcttagga
     2161 ctaaacttga ttcccaattt ctccaactca cggatatccg agtcatcact tggctgataa
     2221 agggtaatag ctgtacctgg taggccattt cgtccagtac gaccaacacg gtgaacaaaa
     2281 aaagataagt cttgcggaat ggcatcattg atgacatggc tgacaccttc aatgtcaatc
     2341 ccacgtgctg ccaaatctgt tgcgacaata tactcaaaat ccagattttg cacctgattc
     2401 atgattcgct tgcgttcacg aggggcaata tcgccatgga tttttgcaac cttcaagcct
     2461 tgagcagtca gatatgaatg caattcatca gcacgcgttt tagtgttaac aaaaatcatt
     2521 gccaaatacg gctgcatcaa ctgagtcaac tggtaaattt gagcattctt atcatgtccc
     2581 ttggtcgaaa tcaaccaatt atcaatggtg tcagaaataa ccgttttggt cttaattttc
     2641 tccataacag gattggataa gtattttttc aagaatggtt gcagtttttg tgggatagtc
     2701 gctgagaaga ccatgaattg caagtctttt ggaagactgc cagcaatctt atcaacagtt
     2761 tccaagaatc ccatatccaa ggtcatatcc gcttcatcaa caacaaatgt cttggcttta
     2821 tgaatagcta aatcaccaga tttaaccaag tcgtagatac ggcctggtgt tccaataaca
     2881 atatgaggct gattgcttgc caatttctca atctggcgag ccttatccgt accacccaca
     2941 taattaacca cacgaacttc gacatctgag tgagctgaaa tctgacgcgc tacttggtaa
     3001 atttgagtag ccaactcacg actcggtgca gtaatcactg cttgtacact atcgctagct
     3061 tcatctaatt gctggaaaat cggtaacaag aaagtatgag tcttacctga acctgttttt
     3121 gattctccta ctaggtcacg acctgccaaa acaataggaa tcaacttgtc ttgcacctct
     3181 gttggagttg taaattttaa ctcctccaag gcttctctaa tatagttttt aaattgaaat
     3241 ttcgtaaatg acataacatc ctcgattcta tctatcttat caattatacc atattttatt
     3301 ccattacagt agtctcactt atttaggcta tttccagtag cttctctagt aagaaaaggc
     3361 tggaatttta tagttccaac ctcttttcag ttattatttc cagtttaaca tagcattcaa
     3421 gccatagtga tcactcactt gtggactctt gttaccatca aatacgacat gtaaattttc
     3481 caccgctaac tctttggtag taaagacata atcgattcga aggggttcag tgttcccttt
     3541 ccagccatca atttcaagcg gaacagtata gctaccactt ttctcttgag caacttcaaa
     3601 tgcgtcttgt aagcctaatg gactagctaa aatagcttgg taaccttcct gacctgctgg
     3661 gttgttaaaa tctccagcta gtaaaagtgg cttgttcaat tttttcaaga cagcctcaaa
     3721 tcgtgcccat tcttcttgaa aacctttatc ccaccaagag agatgaacac tggcaactgc
     3781 tagctccttg ccatcgacta cagtttcagc tagggcaaca cggcgagtat gatagtctgt
     3841 tggatcatcc acatctgaaa ccaaaatttc tctggcttca ataggtgttt tagacaagat
     3901 agccacacct tcgtggtagc ggtcatagcc gatatggtta taggcccagg tccagtagta
     3961 atttttccct tgctcagata acttttcaac caagagtcta acatagtgat cttggtgaat
     4021 aggctcagct gctggcaaag cttgataaag gtcattaacc tccacctctg acgaggtcat
     4081 ctcctgatta atttcttgga aacaaatcaa atcatagtcc ttttcaagaa tatcttcaag
     4141 caaaatctgg aatttttcct ctgcttcttt ctccatccaa ctatgagtat tgagtgttaa
     4201 aaatttcatt cttttctccc aaaataagag gttggaatac agcttccaac ctcaagtata
     4261 ttacaattct actttagcaa ctgctgtttt agctgcaaga gaacctgttt tttctaattt
     4321 aactgattta attgcatcac catttgtgaa gacaactact gttgaagttt cacgtcctgc
     4381 tgcacggata gcattcaagt cagctgtgac aaggagatct cctgctgcaa ctttttgtcc
     4441 ttcagcaaca tgaactgtaa atggtttacc ttcaagactt actgtgtcca aaccaatgtg
     4501 aaccaatact tcaagacctg cttccgtcac aataccaaaa gcatgttttg ttgggaagat
     4561 gcttgataca gtacctgaaa ctggagatac aatgtttcca tttgcaggtt ctactgcaaa
     4621 tccatcaccc atcatttttt gagcaaatac tggatccttt acttgttcca aagcaacaac
     4681 ttgaccgtct gctactgagt aaacttcctc agtaagatct ttgaagtgaa cagtgttttg
     4741 ttgtacttca gtcatttggt ttggaagagt ttcaggaatg atttcacctg aatcaaggat
     4801 atcttggata tcagatttca aaatgtcagc ttttggaccg tagatagctt gaaccccttg
     4861 tcctttcatc acaagaccca tagctccttc tgctttccat tgctctgcat ttcctacttt
     4921 atctgcatct ttaacagtta cacgaagacg agtcatacat gcatcaacat caacgatgtt
     4981 tacacgtcca ccaagaaggt tgataatgtt tacagcttga gagcctgctg caactttcac
     5041 ttcgctgctg gtttcttctg aaccttcagc agtttcgtag tttccgttgc gccctggagt
     5101 tgcgtagttg aatttttgaa tcatgaagtt tgcgataaag tacatgatta cagcaaagag
     5161 aacagttacc caaacgaagt taacgatatc cataccaata ccagcactga ttgcaatagg
     5221 tgtacgagtc aagaactcga ttgaaccgaa tgagtgcata cgtaggttta cgacgtcagc
     5281 catagcgaag gcagcacctt gaacaagtga gtaaacaaga tacataggtg ttgcgatgaa
     5341 catgaacatg tattcgattg gttcagtaac ccctgtcaag aatgttgcaa gagctgttgc
     5401 aatcatcata cctttgtatt tatgtttctt gtcagcatca acattacggt agatagcaac
     5461 aatcacaccc atcaagatac cgaatgaacc gatcatttgt ccaactttga aacgagctgg
     5521 atgtactgta tctaacaagt gttggtattg actagcatca gtacctttaa ggtttacaag
     5581 gtctgttacc catgcaagcc atagtgggtc ttgaccgaat acttgagtac ctttagctgc
     5641 accagttaaa atgtcataag taccaccaag agctgtgtag ttcattggga tagtcaacat
     5701 gtggtgaaga ccaaatggca agagcaaacg ttccaaagta ccatacaaga atggtgcaag
     5761 aattggagca gtttcttgtg agttggcaat ccagataccg aaattattga tacctgtttg
     5821 aactactggc cagaaagcag caagtagaat tgcagcgatt gctgaacgaa gaataactac
     5881 aaatggtacg aaacgtttcc cgttgaagaa tgaaagtgca tcaggaagtt tacggaagtt
     5941 gtagtatttg ttgtaagcag ttgcccctac aaaacctgag ataatcccta cgaatacccc
     6001 catgttcaag gctggagctt caagaacact gataaagtaa tcagcaactt tgattgaacc
     6061 accaaagaaa gtagttacca tagcatctgg atttttcaac atatcgcctg atacaccaaa
     6121 gattgtacca gtgatacggt taatcaagat gaaggcaaga ccagcggcga aagcaccacc
     6181 agcacgttct ttagcccagc ttcctccaat ggctagggca aacaaaatgt gaaggttacc
     6241 gataaccccc caaccgattt gctcaagaat tccacctgtg atgacaagtg gtgtaaaggt
     6301 tgggttaatc atcacgatag acttaccgat tgaaatcatc aaaccagcag ccggcataac
     6361 cgcgataact accatcaaag ccttaccgaa tttttgccaa aattcgaaag acaagacatt
     6421 tttgaatgta tctttcatca ttcaaatctc ctttattttt atttaggcaa acgtttcacg
     6481 aaaacgtttg caccttctat gatttaatta taccacttta attttttttg taaaggcttt
     6541 tataaaaaaa ttacactttt ttctaaaaaa tttctagtgc gccaaatttc aagttcaaat
     6601 tagccatcaa gaagtcttct ctgggggact tctttggaag cccttttctt ctacgcatct
     6661 cttttcaaaa actcttgtag caaaaaagga gattttgcaa tctcctcata aaagcagcta
     6721 ttttacctaa atcttcaaga atcggcgcat ggatattcct gatcccaatg aaccaatgaa
     6781 aaccccaatc acaaatagta gggcaatcat caacggacta aataaatctg gactaatcat
     6841 ggatagattt tgccctacca acgatttgtt gacagattgg taaacaattt gataaacaat
     6901 aaagaccaaa acagatggtg cgatagctcc caataaaccg ataaaggctc cttctaacaa
     6961 gaacggtcca cggatataac tgtttttagc tccgaccaag cgcatgattt gaatttcgcg
     7021 actgcgggaa ataatggtaa tacgaatggt atttgaaatc aagaaaactg cgataaaaat
     7081 taacaaagca gcaatcccta gtccccaaac acggataaat gaagctaact tgaagagtct
     7141 ttctgtattg gcaccgccat cttgaacctc agagacacct tcaatttttt tagcctcttc
     7201 ggctatagtt tttacatcat ttggagtgtt tgcctctaca atataggcat catagagagg
     7261 attagcatct ccttcaaaga ttttccagtt atctcccatt atctcggtta atttttcata
     7321 ttgttcttct ttacttgaaa aggtaacact tttaaccgta gacatgttct tcaaagaatc
     7381 atataccttg tggtagtcat tatttgtaac agtttgacct tctttttcaa ttgtctgact
     7441 attatcttcc acatcctttc ggatataaac tactacacgg acattatttt caatatctgt
     7501 agctagtttc gctgtattga aaataacaga tgcaaatatt gccaccaagg tcaaagtaat
     7561 catgactgaa ctgacagcag ctactgtcat ccaaccattt cgtttcaaac tttttaaggc
     7621 ttcaaataaa tggcgaaaaa atctactaat catcgtatcc atactctcct tttgattcgt
     7681 cacgaacgac acggccattt tcaatggcaa tgacacggtg gcgcaaggta tttacaatct
     7741 ggctattatg agtcgccatc aaaatagttg ttccttgtag gttaatccgt tccaagagat
     7801 tcataatttc ccatgaatta tccggatcca gatttcctgt tggctcatca gctatcaata
     7861 ctttgggatt atttacaatt gcacgcgcaa tcgcaatccg ctgttgctcc ccacctgaga
     7921 gttcatttgg gaaagaacga accttatgct tcaatccaac caagtccaaa acttccatca
     7981 ctcgtctttt gatattacgg cgattttccc cgattacttc catagcgtaa gcaatatttt
     8041 catagacagt tttctttggt aacaatttat aatcctggaa gacaacccca acactacgac
     8101 gtagaagcgg gacatctttc tttttgatct taaccagatt aaaaccagca actgataggc
     8161 ttcctttatc gatttttact tcacgataca gagaacgaat aaaagttgac ttccctgctc
     8221 ctgaaggtcc tacgatgtaa gcaaattccc ccggttgaac gctgaccgaa acaccgcgta
     8281 gagcagtcgt tccgttgtcg tattttttaa cgacatctct catttcaata attgacatgt
     8341 gagttccttt ctatcttagc taattcgcca cttgagataa gcatcgataa aaccatctag
     8401 gtccccatcc ataaccttat ctacctgagc aacctcaaag ctagttcggt gatcttttac
     8461 catagtataa ggcgtgaaga cataagaacg gatttggctt ccccaagtga tctccttttt
     8521 ctcacctttg agagaatcta cctccgcagc cttcttctct tgctccattt gatagagctt
     8581 agcctgcaac atcttcatgg cacgatctct atttccatac tgggtacgat ccactgttga
     8641 ttggacaaca attccagttg gaatgtgggt taaacgtaca cctgttgaaa ccttattgac
     8701 gttttgtcca ccggcaccac ctgaacggaa ggtatccatc ttgatatcat cttcacggat
     8761 ttccacttca atagtatcat ccaattctgg catcacttct acagatgtga aagaggtatg
     8821 gcgacgtttg gcagagtcaa atggtgagat tcgcactaag cggtgaacac ccatttctga
     8881 cttgaggaga ccataggcat taggcccttc aaatgataaa gttaccgact taataccagc
     8941 ctcatcacct gcttggtaat ccaacacttc cactttaaag cctttagcat taccataacg
     9001 agtatacata cgaagcaaca tatcacccca gtcctgcgcc tcagtaccac cagaacctgg
     9061 atggatttcc aagatggcat tgttgtggtc ataaggttct gacaagagta gagtcatctc
     9121 gtagctggtc attatcttat caagttcggc taactgcgct accagttcat catgcactga
     9181 ctcgtcttca gccaaaaaat ccaataaaat ttcgacttca tcctgcaact cttccatctt
     9241 atggaaggta ttgtaagtgt tttttaattc atttaattct tgcgacgttt tttgggccgc
     9301 aatattatcg ttccaaaaat caggttctgt catcttgttt tccaagatga caatctcttc
     9361 ctctagccct tcgaggtcaa agagaccccc tgaaagaagc taatttttca cgatttgcgt
     9421 caattttctg acgaattact gaaatgtcca taaatactcc ttttttacat tatttcatta
     9481 tagcatattt tatcatttct ttccatcttt ttctctaatc cccttttcat gaaaaaagaa
     9541 gcctttgggc ttcccttctt acaagacttt tgctgaagtg cgagcgattt cttccacttg
     9601 aataccattt gcttcaaatt tttctttcaa ggctggtaaa tcaattgatc catcgatttg
     9661 cacttcgata atcaccttac catccttacg cggaatattg actgtatggg agatattcaa
     9721 attttcttct acaatcaaag aaacaatttt tccaagaaca ccaacttcat cttctgtaac
     9781 aaagcgtaca cgaatccctt cttcgccata acctgcaatt tcaagaaagg cttggaaaac
     9841 gtcacggtca gtaataactc cgtatacttg atggttatct acgacaggga gaatactaat
     9901 cttatttttc aacatcagat aagttgcatc ttctagacta gcatagcctg agacagtgac
     9961 aacatcgcga atcatgacat cttttacttt tgtcttattc agaagataat tcatctcata
    10021 gatagaaaga cttgttgctt tagatggact tgcttgtgca atggttccct cagtcaccaa
    10081 accaactaat tgatcatttt cgataacagg cagacggtgc aaaccttgct ctctcatcaa
    10141 atctgctgca tgagatactg ttgtatctgg actaatataa actaccttgc gggtcataaa
    10201 atctttaact gccatgagac ttctcctttt ctattcttat ccctattata caatcttttt
    10261 gtaaatctat caaacgctta catttctttt tcgaaattca gaaaagtatg aataagctag
    10321 caaaaagagc tctgaaatcg agctctgtga atgaaggtaa gaaatttttc attcgatttt
    10381 ttcaattatt agaaattaag ctttcaatgt agatgcagat ttgtttgcaa tctcaatcta
    10441 ccgactaaaa aggtcccccg gactatattg atgattactt cgtaatctcc atctgccgac
    10501 taaaacaatc cactggattg ttttagccac ctagatatgc ttttctgact tcttctgatg
    10561 aagcgagttc ttttcctgtt cctgatagga cgattttccc tgtttccagt acatatcctc
    10621 ggtcagagat tgcaagtgct ttattggcat tttgttcaat caagaggacc gttgttcctt
    10681 gcttctgaat atcttgaatg atatcaaaaa tttcttggat aaagattggg gcaagtccca
    10741 ttgatggttc atctaaaaga agaagttttg gtgttgacat gagggcgcgt cccatggcaa
    10801 gcatttgttg ttccccccct gaaagagtgg ctgcatcttg gttcttccgt tcttcaagac
    10861 gaggaaagcg tgagaaaacc ttcttcaagt tagcttgatt ttcttcacga tttttcttta
    10921 agaaagctcc catttcaaga ttttccataa cagtcaagcc aggaaagacg tggcgtcctt
    10981 ctggaacttg tgaaagacca cttgccacga ttttctgagc tggcattttt tggatttctt
    11041 gacctaaaaa ttcaatcttt cctgaacttg gtcgaaccaa acctgacaag gtgcgaagaa
    11101 tagttgtctt acctgcaccg ttggcaccga taagggaaac aacttctcct tcattaactt
    11161 caaagcttac atcacggact gcttggatca taccgtaatg cacagaaaga ttttcaactt
    11221 ttaacataga cattaggctt cacctcctag ataagcttcg ataacgcgtt tattggtctt
    11281 aatttcgtct ggagttcctt gagcaattaa acggccatat tcaagtacgt agatacgttc
    11341 tgttacttcc atgaccagat tcatatcgtg ttcaatcaac atgattgtaa tcttaaattc
    11401 atctttgata cgacgaatta actcagtcaa ttcggctgtt tcctgtgggt tcatacctgc
    11461 tgctggttca tctaagaaga gaattttagg ttccgtagca agggcacgaa caatttccaa
    11521 acgacgttgt tgtccgtagg aaagattttt agcaagagtc tctgcatcac catctaaatc
    11581 aaagattttc aacaattcca aagctttagc ctttaattct ttttcactct tgtaaaaagc
    11641 tggtaagcgt aagaaactag taaaaacatg ctgtttgtga tggtttccaa aagcaatcaa
    11701 aacattatct aaaactgtta aatctttaaa gagacggata ttttggaaag tacgtccaag
    11761 tcccaaagag gcaatcttat aaggtgattt cccattcaaa aggtgaccat ctagggttac
    11821 tgttccctcg cttggttcat aaacaccggt caaaaggttg aaaagggtgg ttttcccagc
    11881 tccgtttgga ccgattaatc caaccagttc cccttcgttc aattcaagag tcacatctcc
    11941 aacagctgtt agaccaccaa aatgtttggt taactgtttt acttcaagta atgccattag
    12001 ttttgttcct ccttcttaga ttttttaaag aaacgtgata ggctcagttc ccatgttcca
    12061 aggagtccac ctggtctgaa aatcattacc aataccaagg ccaaagcgta aataatcata
    12121 cgcacactag taacatcttg gagaagcata ttcaaaattc ccagaacaat agccgaaaca
    12181 atcgcacctg taatggaacc gagtccacca aatacaacaa taatcaaaac gttgattgag
    12241 ttgatgaagg tgtaatcttt cggtacaaca gacccgataa atcctgcctg aagtgaccca
    12301 gcaatacttg cagtaatggc accaaagaca aaagcgatga ttttaatttt agtcgtatta
    12361 accccaactg actcagcagc gatttcatct tcacgaacag agagggttga acgaccaatt
    12421 gggctacgca agaagttcaa ggttgcaatg gttgtaatca cgacaaagaa gtaaaccatt
    12481 tgccaagttg taaagttagg aatccctaag atacctgccg caccatttgt aaggcttcca
    12541 ccattgatga taaagatacg gataatttca gaaacaccca gagttgctac cgcaagatag
    12601 tcccccttca agcgcaaggt tggaatgccg acaagtaagg caactgctcc tgaaagcaaa
    12661 gcccctacaa gcatagctcc aaagaaggca ccgtaggttg gtgatttaga accaataata
    12721 gctgctgcat aggcaccaat cgccatgaaa ccagcatgac caagtgaaaa ttgtcctgaa
    12781 aaaccaacga ttaagttgag accaacagtc aaaataatat taattccaat ttgttgtaaa
    12841 atctgtacat agaatagatt aagtactccg actgaaacca gtacactaat caagctatag
    12901 ccagctaaca aaaggagtaa ccatagaata ttaactttta aattttcctt catcgtttac
    12961 accttctctt tcacattctt accaaggata ccagctgggc ggacaatcaa gatcaacaac
    13021 aagattccat aaacaatggc atcacggaaa tctgacatcc caaaggctgt cgcaaaggtt
    13081 tccaatagac caatcacaaa gccaccaaga gcagcaccag gaataattcc gataccacca
    13141 agtactgcgg caacgaaaga tttaagacct ggagtaaccc ccatcaaagg ctcaagagag
    13201 ttataataaa gagcaatcag aacaccagcc gcacccgcaa gagcagaacc caaagcgaag
    13261 gtaaagctaa tcgtacggtt tacattgatc cccatcaatt gcgccgcgtc gctatctact
    13321 gatactgcac gcatggcttt ccccatctta gtcttttgga caatgacttg taacaaaatc
    13381 atcaaaatca aggaaatgcc caaaatcatt aactgcacat ttgttaagct aattggtccc
    13441 aaatcatatc gaactgtttg aatcgcttga gggaaggcac gggtattggc accaaccaga
    13501 tagaccattc catactccaa taggaaagaa accccaatag ccgtaatcaa aacagcaata
    13561 cgagtagagt ggcgcaaagg tctgtaagca agaaactcaa tcacgatacc aagaatagct
    13621 gtcgctagca tagctacaat aagcgctaca aagaaattca tttggaaaga attgatcaag
    13681 aaataaccga taaaggctcc catcatataa atatcaccat gggcgaagtt gatgagcttg
    13741 ataattccgt aaaccatggt atatcctagg gctaacagcg cgtaaacact acctagaatc
    13801 aaaccattta cgagttgttg gagcataaga ttcactcttt ctatttataa ttccgagggg
    13861 tttccctcac tttttgatag gttcttatac tcaatgaaaa tcaaagagca aactaggaaa
    13921 ctagccgcag gttgctcaaa gcactgcttt gaggttgtag ataagactga cgaagtcagt
    13981 cacatatata atccaaggcg acgttgacac agtttgaaga gattttcgaa gagtattaaa
    14041 catcgaaaca gggagtgagt caaaggctca ttccctattt caacattttt ctattatggt
    14101 tttacaactt ctgctgcttc aactttacca ttgttcatgg tcatcatgta agcagttttg
    14161 actgtgttgt ggtctgcatc gaagcttgtt tgaccagtta caccttcaaa atcttttgtt
    14221 ttagcaaggt tatccttgat ttcacctgaa tttttagcac cttttgctgc gtttgctaca
    14281 aggtgaactg aatcataagc caaggctgca aatgttgaag gctcttcatt gtacttagca
    14341 cggtaagcgt caaggaaggc tttagcttta gctgaaactt ctacagtagt tgaaaagcct
    14401 gagataaagt agatgtttga tgctttttca gcagttgctt gttgtacaaa ctcctcaccg
    14461 ttgaatccat caccaccaac gattggtttg tcaattccca tgccacgcgc ttggtttaca
    14521 atcttaccag cctcattata gtaaccagga acaacgatag catcaaagtc tttccctttc
    14581 atttttgtaa gggctgcttg gaagtctgtg tcacctgcta cgaaagtttc atctgcaacg
    14641 atttcaccct tgtatgactc gcggaaagat ttggcaatcc ctttagcata gtcactggca
    14701 ttgtcagtgt aaagaacaac tttcttagca tttaattttt cagaaacata gtttgagata
    14761 atttttcctt ggaagctatc ttggaaagtt ccaataaaga ggtaatcttg acctttagtc
    14821 aatccatctt gagtcgcact tggtgagatc aatggaacac ctgcttttgt agcgttcgct
    14881 accgcagctg cagtcgcacc agatgtcgca ggtcctacga ctgctgatac tttagattgg
    14941 gttacaaggt tagttgtaac tgaagcagcc tcagctgttt cagacttatt atctttatcg
    15001 attacttcga tttgttttcc atcgatacca cctgcggcat tgatttcatc aacagccaat
    15061 tgggcacctt tttgttcagc tgttccgtat gcagctaaag aacctgattc ttcaaagtta
    15121 aacccgattt taattgtctt ttcctctact gagttaccag cagtgttgac tgctccagac
    15181 ttcacttctc cacaggctgc aagaagtgct acacttgcaa gcgccacaaa cgatagggca
    15241 aattttttct tcatcttttt tgtctcctta tttcttaaat agtctgttaa gaatataccg
    15301 aattatcaga aaattgtcaa tgttttcctt gaactttttc gatgataacg ttttcctatc
    15361 gataaagatt gcccacaaag ggtgtttcca actcttggat atgacaaacc ctaacttttt
    15421 taataaattt ttccttgctc aagcgtccga ccaattgctc cacttcttga gttggaacat
    15481 agagttgtaa gtaacgatgt ttcttggaat gataggtaat atctccataa tcctgcagtt
    15541 ttttggcatc acgattatag taaagataga taatcaagcc agagcgattg actttttcaa
    15601 acatgataaa tcctctttct aagaaatctc tccctattat accaaaaaaa gcaaacccag
    15661 tcgagtttgc cttctatcat cattagttca atgaattgtt ggccataatt tcatcaataa
    15721 agccatattc aagtgtttcc tgggcgctca tccagttatc acgttctgca tctgcatgga
    15781 ctttttccat tgactgacct gaattttcag ccaagatttt ttccaaggta ttacgagttt
    15841 tgagcaagtg ttctgcagcg atagccatat cagtttgttg ggtaccacca cctgtaccgc
    15901 ccattggttg gtgaatcatg tattcagcat ttggaagcat gaaacgtttg ccttttgctc
    15961 cacttgatgc gatgacagtc cccatagatg cagccattcc cataacaatg gtttggacat
    16021 ctgccttgat aaagttcatg gtatctacga ttgccaaacc agctgaaaca gaaccacctg
    16081 gtgtattgac ataaaggtaa atatcttttg tactatcttg ggcatccaag aaaagcaatt
    16141 gggcaataac agagttagcc atattgtctt caaccggacc tgtcagcata atgatacggt
    16201 ctttgagaag acgtgagtaa atatcgtaag aacgttctcc acggcttgtt tgttcaataa
    16261 ctacaggaat cattcatttc tccttttgag ttttaatttt gttggtcaaa tgactgaaga
    16321 taagactatt ataatatctt ggtcaaaaaa ggtcaaattt ttgctctgct ttcattagac
    16381 agaaacaaaa acccaacctc ctttcgtgac tagaaatact tttccaagtc attcttcttt
    16441 tcgatcttat tttgtaccga acaagcggtc tccagcatct ccaagacctg gaacgatata
    16501 accgtgttcg ttcaaacgtt catccaaggc tgctgtaaag atttctacat ctggatgagc
    16561 ttcttgaagg gcttttacac cctctggagc agatacaagg cagacaaatt tgatatttga
    16621 tgcgccacgt tttttaagag aatcaacagc caagattgct gagccacctg ttgccaacat
    16681 tgggtctact acaaaaattt gacgttggtc aatgtcctca ggcaatttca ccaagtattc
    16741 aactggttga agtgtttctt catcacggta cataccgatg tggccaactt tagcagctgg
    16801 aaccaagctc aagagaccat caaccatccc gatacctgca cgcaagattg ggacgatggc
    16861 caatttctta cctgccaatt gtttttgaac tgtttttgta attggtgttt cgatttccac
    16921 atcttctagt ggaagatcac gaagtacttc ataccccatc aacattgcaa tctcatctac
    16981 tagctcacga aaagcttttg tagaagtatc tgtacgacgc aagattgaca atttgtgttg
    17041 aatcagtggg tgattaataa cttcaatttt tcccattttt ggaattcctt ctttcaattt
    17101 attcttctta ttataccaaa aaacggttta aaaatctttc taaaccattt atttttgata
    17161 atttttacat tagatcagcc tctttaagag ctgtctgtac tgtctcaagt ggtaaatggg
    17221 tcaattctgt ccctttttct tgataaaggt attgggcgta gtcgtccatt cggtactggt
    17281 tgatataaac cacgcgcttg cagccgacct gaagcaattg ttttgtacag ttgagacaag
    17341 gaaaatgggt tacataggct gtaaagcctt tgggaacacc acgctcagca ccttgaagga
    17401 tagcattgac ctcagcgtga agggtgcgaa cgcagtggcc ttcaatgacc aaacattcgt
    17461 gatcaataca atgctcagtc cctgacaccg aaccattgta accagtggaa ataaccttat
    17521 tatcttttac cagaatcgcg cccactttag cacgtttaca agtggaacga ttcgcaatta
    17581 gtagagcttg ggctgcaaaa tactcatccc aggccagtct tttttcagtc atctcttttc
    17641 tcctttttct ctatttttta aaaaatggta aacctaaatc tgcaatcttt tcagctggta
    17701 ccttcatgcc atccttgatc cattttagaa ggacagagac gatggctgag ctccagaagg
    17761 aatgaagata agagctgaca ccttttgatt tcccatggta tttttctaga aattcctgca
    17821 tggcttggac aaagattttt tccagatggt aatccaaggc caattgaatt actctagctt
    17881 cctttctggc ctcccggaaa aggtgaaccc aaaccaaata aaggtctgtc tttaaatcgt
    17941 aatgatgcag ctgttccata atattgtgga cagttcgttt aaagacgctc tctaaaattt
    18001 cctctttgga gtcataattg cgataaaagg ccgcacgcga aacacctgca cgtttgacca
    18061 attcagaaat actaatcttg gtcagttcct ttttttccaa gagttgcaag agggctgttt
    18121 caatggcttc tctggttaat aaattggatt cttggtttga ttttctgaga ttttcaagag
    18181 acttttcaga gattctacgt tcagacataa cattttcttt ctacttgtca caacagacgg
    18241 atgatgcttt tgtttcaagg gttttcatga tataattgta aaaaaagaca gaacctttgt
    18301 caatgtataa ctgacaaaga tggagaattt ctatgacttg gaagattatt gctgactctg
    18361 gttgtgatta tcgtcaactg ccaacaccag ctattaacac aacctttgta agtgtcccct
    18421 taaccattca agtagctgat caggtctttg ttgatgacgc cagtctcgat attgaccaaa
    18481 tgatggaaac catgtatgca actgcagaag cttcaaaatc ggcttgtcca agcccagatg
    18541 actatttgcg agcatttgaa ggtgccaaaa acattttcct agtaaccatc acaggtaccc
    18601 tttctggcag tcacaatagt gctcaactag caaagaatat ttatctggaa gaccatcctg
    18661 acactaagat tcatgtgatt gatagtttat ctgctggtgg tgaagttgac ctactcgtag
    18721 aaaaattgaa tgacttgatt gaccagggct tgtcttttga agaagtggtt gaagctatca
    18781 ccgcctatca agaaaaaact aagttgctct ttgtcctagc caaagtcgat aacttggtga
    18841 agaacggccg tttgagcaag cttatcggta cggtcgttgg ccttctcaac attcgtatgg
    18901 tcggaaaagc tagtgaaact ggaactctcg aattgctaca aaaagcaagg ggatcaaaga
    18961 aatcagttca agctgcctat gatgagttag taaaagctgg atatgctggt ggccgtattg
    19021 tcatggccca acgcaataac gaaaaatgtt gtcaacagct ctcagagcga atccgtgaaa
    19081 ccttcccaca agcggatatt aaaattctac caacctctgg tctctgcagt ttctatgcag
    19141 aagagggcgg tttgctgatg ggctatgaaa ttgattaatt gcattcttga caagaggtga
    19201 ccatcatctc ttgttttttt gtggtacaat agagctatga aacattttga tactattgtc
    19261 atcggtgggg gacctgctgg tatgatgtct acgatttcca gtagctttta tggacagaaa
    19321 accctcctca tcgaaaaaaa tcggaaactt ggaaaaaaat tagctgggac tggtggggga
    19381 cgttgcaatg tgaccaacaa tggtagctta gacaacctgc tagctggaat tcctggaaac
    19441 ggacgctttc tttacagtgt tttctcccag ttcgataatc atgacatcat caactttttt
    19501 acagaaaatg gtgttaaact taaggtcgaa gaccacggac gcgtctttcc agccagtgac
    19561 aagtctcgga ctattatcga agctttggaa aagaaaatca ctgaactagg tggtcaagtt
    19621 gctactcaaa tagaaatcgt ttctgttaaa aaagtagatg accagtttgt ccttaagtca
    19681 gcggatcaaa ccttcacttg tgagaaactc attgtcacaa caggtggtaa gtcttatcct
    19741 tcgactggtt cgactggttt tggtcacgag attgctcgcc attttaagca taccatcatc
    19801 gagcttgagg ctgctgaaag tcctttatta acagattttc cacataaagc cttacaaggg
    19861 atttctctgg acgatgtgac cctaagttat ggtaagcatg tcatcactca tgatttactc
    19921 tttacccact ttggtttgtc aggtcctgct gccctacgca tgtctagctt tgtaaacggt
    19981 ggggaggttc tctcactcga tgttttgcct caactttctg agaagaactt ggttacattt
    20041 ctagaagaaa atcgggaaaa atccttgaaa aacgctttaa aaaccttgtt accagaacgc
    20101 ttggccgaat tttttgtaca aggatatcct gaaaaagtca aacagctgac tgaaaaggaa
    20161 cgagaacagc ttgtccagtc cattaaagaa cttaaaattc ctgtaactgg aaaaatgtcc
    20221 cttgcaaagt cctttgttac caagggtgga gtcagtctca aggaaatcaa tcctaaaacc
    20281 cttgaaagta agctggtacc tggcctccac tttgcaggcg aagttatgga tatcaatgcc
    20341 cacacgggtg gctttaacat cacttctgcc ctctgtaccg gctgggtggc gggaagtctg
    20401 cattatgatt aaagattaaa ggttgtgaag aatgaacaga agagaggcag tcgaatttgt
    20461 taacatgtgt atgattaaaa acggagataa ggtcctggtc caagaccgag ttagtcccga
    20521 ctggcctggc attacttttc ctggtggtca tgttgaacgt ggcgaatcct ttgtcgatgc
    20581 tgtcattcgt gaagtgaaag aagaaactgg tctgatcatt tccaaacccc aactctgtgg
    20641 tatcaaaaac tggtatgacg acaaggattg tcgttatgtc gtcctttttt acaagacaga
    20701 acactttact ggtgaactcc agtcttcaga cgaagggaaa gtttggtggg aggactttga
    20761 aaatctttct catctaaaac ttgcaaccga tgatatgtct gatatgcttc gtgtgtttct
    20821 agaagaagat ctcagtgaat tcttttacta caaaaacggt gacgactggc tttatgattt
    20881 gaagtaaaaa atatgctagg aaattcccaa tgtcattaag ttaagaaatt caaatacaat
    20941 tctgtatttg ggtctctttt ttatgtgata aactatagtt aaggaggtat ttcccatgat
    21001 aaaacagata aaagcccact tgaataagag tattcagagt atcattggcc aaaaagttga
    21061 gttcgtcaaa caagatgaac aggcctttac tcgtaaaaga aggttatcac tagaaactat
    21121 gattcgtaca attctgggca tgggaggaaa atcactatca aaagaattac tagatgccag
    21181 actgacagtt tcaaattcag cctttgttca aagacgctat cagataaaac ctgaagcttt
    21241 ctatgcccta tttaaagaat ttacagcacc tattccactt aatactgatt ttccaatatt
    21301 cgctgcagat gggagtgata tctgtattcc tcgaaatccc atggatacag aaacctctat
    21361 ccaaacccaa acggatgtta aatcctataa tctcatacac ataaatgccc tatacgactt
    21421 gacgactgga gtgtatagag atgtctctat tcaagacaaa catgcacaac atgagcgctt
    21481 agctctgatt cagatgacgg aggcttctcc ctttcgagaa agctcttgtt atcatggata
    21541 gaggctatga aagttacaat ctcatggctc attttcaaga aaaaggttgg ctttatatca
    21601 tccgtattcg agatggaaaa caatccatgc cttcctcctt caacttgcca aatacggagt
    21661 gttttgatca aaaagtttct ctaaaattat cacgaaagca aaccaatcag ctcaaaaaac
    21721 tttatcgtga ttttcccaat gactatcatt ttattccaca caattctatt tttgattttc
    21781 ttccagaaac aagtcgaaaa caagatcctg taacactcta tgaacttcct tttcgtatgg
    21841 tgcgtttaga agtggaagaa ggaaaatacg aaactttagt gacgaataca gactattcag
    21901 tccaagaatt aaaaaatctc tacgccagta gatggggcat agagactagt tttcgtgacc
    21961 tgaaatacag tattggcttg gtcaattttc acgccaaaaa gaaggaaggg attctccaag
    22021 aaatctttgc tcgctttaca aattttaact tttgtcgttg ggtaaccttg caagttgcca
    22081 tcgacagtag tcacaaaaaa caaagatata aagtgtgttt ctcagatgcg gcttatgcct
    22141 gccgtttgtt ttttaacggt tccctttctt ccctccagtt gaaaaactac ctcaagaaac
    22201 agttatctat tattcgaccg aatcgaaaat attcaagaaa gataaaagct caatcggtag
    22261 ttgatttcat ctatagagta acataaatct caaaaaatag ggtgaaaaaa cctttatttg
    22321 tcatgcaaaa aaatagaaga tgtgatagag aatcactttg atgatcccaa tcacacctcc
    22381 tattcaagta gttagatcac taacttaatg acattgagga aattcctagc ctattttttc
    22441 tgcatttgtc tgaacgtaag ctgcaatggc atctgacgtg tactgggctg ttccagaacc
    22501 aaacttgtca atgttttcct taaactctgg gttgtagacg taacctttac cgatatgacc
    22561 gaatacctca atagagcagt caaatccata agtgcgaatg gcttgcaaga gcttggctgc
    22621 ttgctcttgg ttttcggttg ctgttgcagg taaaccaact tgaagatttt gtgccaaagt
    22681 ttgaaagact tggttaaagg cggccgtagc ctcgtcttcg tgaccttttt ggcgttcgag
    22741 cgcttgtccc atgacttctt gaccatattt ctctaccgct tcttggtggt atttttgatt
    22801 gtcttgatag ctaaatcccg tgaatttttc ctcaatggtc atttttcttt ctcctttttg
    22861 ttcttgaata gttttttgca aggtggaaat caaggtatcc agatgttgcc tttcgcgagt
    22921 tagatagtcc aactgcctag tcaaatgggg caataaatct gtcctttctt cctttaacag
    22981 ctctgctatt ttctctaaag aaaagcctag atatttgtag taaagaatga cctgaaggcg
    23041 ttccaaatcc tcttgactgt aggttcgata gccgttttcc gactttaagg ggaccaagag
    23101 tcctatcttg tcatagtgat gcagggtctt gacagagaca cctgaaagct gcgcagcttc
    23161 ttttatatgg tacatgattt cctccttaca atgatagtat aacccctccc cttaggtcag
    23221 agtcaagcgt ttttgagaaa attttttaac ttttttgaga aaggtgtgaa aacttgaaaa
    23281 tgattttctt gacagacctt agaaaacatg ataggatagt caagtctatc aatcaaacag
    23341 aaggctattt gacaactcaa gtagcttttt cttattttga aaaaggagat cagagtttaa
    23401 ctatgtcaga aaaatcacaa tgggggtcga aacttggttt tattctagca tctgctggct
    23461 ggccatcggg cttggttccg tttggaagtt tccctacatg actgctgcta atggcggtgg
    23521 aggcttttta ctaatctttc tcatttccac tattttaatc ggtttccctc tcctgctggc
    23581 tgagtttgcc cttggccgta gtgctggcgt ttccgctatc aaaacctttg gaaaactggg
    23641 caagaataac aagtacaact ttatcggttg gattggcgcc tttgccctct ttatcctctt
    23701 atctttttac agtgttatcg gaggatggat tctagtctat ctaggtattg agtttgggaa
    23761 attgttccaa cttggtggaa cgggtgatta tgctcagtta tttacttcaa tcatttcaaa
    23821 tccagccatt gctctaggag ctcaagcgac ctttatccta ttgaatatct tcattgtatc
    23881 acgtggggtt caaaaaggga ttgaaagagc ttcgaaagtc atgattcctc tgctctttat
    23941 catctttgtc gtcatcatcg aacgctctcc cagtttgcca aatgccatgg aaggggttct
    24001 ttacttcctc aaaccagact tttcaaaact gactagcgct ggtcccctct atgctctggg
    24061 acaatctttc tttgccctct cactaggggt tactgtcatg ttgacctatg cttcttactt
    24121 ggacaagaaa accaatctag tccagtcagg aatctccatc gtagccatga atatctcgat
    24181 atccatcatg gcaggtctag ccattttcca agctcggtcc cccttcaata tccagtctga
    24241 agggggaccg agcttgctct ttatcgtctt gcctcaactc tttgacaaga tgccttttgg
    24301 aaccattttc tacgtcctct tcctctttgc gactgtcact tcttctgtcg tgatgctgga
    24361 gatcaatgtg ggcaatatca ccaaccaaga taacagcaaa cgtgccaaat ggagtgttat
    24421 tttaggaatt ttgacctttg tctttggcat tccttcagcc ctatcttacg gtgtcatggc
    24481 ggatgttcac atttttggta aggccttctt tgacgctatg gacttcttgg tttccaatct
    24541 cctcatgcca tttggagctc tctacctttc actttttaca ggctatatct ttaaaaaggc
    24601 tcttgcaata gagaaactcc atctcgatga aagagcatgg aaacaaggac tgttccaagt
    24661 ctcgctcttc cttcttcgtt tcgtcattcc aatcatcatc attgtggtct tcattgccca
    24721 atttatgtaa tcaaaaagga cttgagtagt gaactcaggc cctttctttt ttatggatga
    24781 ctaacaatta attctaaatc ttgcccttct aaagtccaag attcaacatc acttagtacg
    24841 ataaagtggc tccctttttg gattggatag ttttttccat caacagtcag ttgaccttgg
    24901 ccagctaaga tactaaacaa actgtaatca gctgtcttct caaaatcaac ttttccagtg
    24961 atttcccact tgtaaactgc gaagaaatca ttagaaacaa gtaaagtgga acgcaaatta
    25021 tctgctttaa cagttacagg acggctattt gctggctcgc caatgttcaa aacatcgatg
    25081 gatttttcaa ggtgaagttc acgcaagttg cccttatcgt cctttcgatc aaagtcatag
    25141 acgcggtaag ttgtatcact agactgttgg gtttcaagaa tcaagatgcc aggaccgata
    25201 gcatgcatgg tgccacttgg tacatagaag aaatctccag ccttgacagg gactttggta
    25261 agcaaggtat cccagttctt gtcctcgatt tgctggcgga gttcttcttt tgacttggca
    25321 ttgtggccgt agataatctc tgaaccttca tccgcagcga tgatgtacca gcattctgtt
    25381 tttccaagtt cgccttcatg ctctagtcca taagcatcgt ctgggtgaac ttgaacgctg
    25441 agccagtcgt tagcatccag aatcttagtc aaaagcggaa atacaggctc aggacgattg
    25501 ccaaacaatt cgcggtgttc cgcatacaaa gtagcaagat ctgttccctc gtaacgacca
    25561 ttggcaactt tagaaacacc atttagatga gctgagatag cccagtactc tccgactttt
    25621 tcacttggga tgtcgtagcc aaactcatca cgtagcttgg taccacccca gattttttct
    25681 tgcataactg attgtaaaaa taatggttct gacatcttaa tctcctgtct gatttttctc
    25741 ccctcattat agcaaaaaaa gagttccatt tgaactcttt tttacatctt ataaagcagg
    25801 gagaagattt tataaaaata gtaaacaaat gtgctctact cgatgcttac accattgcta
    25861 tcaatgacat ccttgtacca atagaaggac ttcttcttgc tccgtttgaa acttccatga
    25921 ccagcattat ctcgatccac atagataaag ccatagcgct tgttcatttc gcctgttcca
    25981 gctgaaacca gatcgataca accccaagtc gtataaccaa gcaagtcaaa ctccatcttg
    26041 gtaaatggca tctcgcatgg ccttgatgtg ggcctctaag taagtaatcc gatagtcatc
    26101 tgctacataa ccattctcat ccggtgtatc catagcaccg agtccatttt ctacgataat
    26161 actaaactaa aatcaaaaag cattatataa tagtgatatg aaatcaacta aagaagaaat
    26221 ccaaaccatc aaaacacttt taaaagactc tcgtacagct aaatatcata aacgccttca
    26281 aatcgttcta tagtaaaatg aaacaagaac aggacaaatt aatcaggaca gtcaaattaa
    26341 tttatagaaa tattttagca gccaaggtgt actgttatag attcaataca ctatagactg
    26401 taatcaaaca acgatttggc gaaatgtaaa aaaatatgag gagttcggac tcgactctct
    26461 ccttcaagaa acacgtggtg gtcgtaacca tacatatatg acagttgagg aagagaaagc
    26521 ctttcttgct cgccatttga aggctgcaga gacaggagaa tttgttacaa ttgatgcctt
    26581 atttcaggct tataaaaagg agttaggtcg ttcctacaca cgtgatgcct tctatcaact
    26641 gttgaagcgc catggttggc aaaatattat gccacgtcca gaacatccta agaaagcaga
    26701 cgctcaaacc attgttgcgt ctaaaaataa aatctcaatt caagaaaaca agaaagcgct
    26761 ttaaaaccag tagacgtttt cgtaaggttc gcttgatgta ccaagatgaa gctggtttcg
    26821 gtagaatcag taaactggga tcttgttggt ctccaatagg agtaggtcca catgtccata
    26881 gtcactatat acgagaattt cgctattgtt atggagctgt tgatgcccat acaggcgaat
    26941 catttttctt aatagctggt agatgtaata ctgagtggat gaacgccttt ttagaagagc
    27001 tttcacaagc ttatcaagat gattattttt tactcgttat ggacaatgct atatggcata
    27061 aatcaagtat cttaaagatt ccgactaata ttggctttgc atttattcct ccatacacac
    27121 cagagatgaa ctccattgaa caagtgtgga aagagattcg taaacgtgga tttaagaata
    27181 aagcctttca aactttggaa gatgtcatga atcaactcca agatgtcata caaggactgg
    27241 agaaggaggt gataaagtcc atcgttaatc ggaaatggac tagaatgctt tttgaaagca
    27301 gatgagtatt atatgcaatt tctttatata aaaagatcgg attgctccga tctttcaata
    27361 gttcatattc tcaatttcta ttttaaaaat agctaaggtt aacgtcaaat gactacgcga
    27421 cctatttcat acgataaaaa tcaagcacta gaccagcagg tcctttaact aataaggact
    27481 ctgttcccca atcggttaca gttggtccgt gtaaaacctt tataccaagc tcgttcaacc
    27541 gtttgtagtt ctggtctaca tcctcaacct cgatatgaat aatgattcct gactgaaagt
    27601 tttccaaagg aaccaaatga ttttgtgaca acataagaca gtgactgcca atcgtaaact
    27661 gagcaaaacc atcatcagca taatctgcct ttttatccaa gatatgctcc aagtcagcac
    27721 agacttgggg aacatttgaa acgataatat ctaattgatt taaattcatt tactctcctc
    27781 cataaaaaga ccgaattgct ccgatctttt aaagttccgc tctatgaaaa tcaaagaata
    27841 aagtctacaa gtttcatatt tgattttcgg cgagaggaat tatttaattg cgcgtgattg
    27901 caatccttct tcttccaaga agagacggaa tggtacgagt tcttctgctt cgtatttttc
    27961 cttgaaggct ttaatagctt cttctgagtg aagttttgga tccaattcaa gtacttctac
    28021 tggaagtgga cggtgttgag tgatgcgagc atcgatgaca acagttttac cttctttgtt
    28081 caatttaaca gcttctgcaa caactgcatc gatgtcttcg atacggtcaa ctgtgaatcc
    28141 aacagctcct tgagcttccg caattttagc gtagtcagcg tttgtgaagt ctacaccaaa
    28201 caagtgtttg tttgtatctt cgtatttgtt cttgatgaag ccgtactcag catttgagaa
    28261 gacaaggttg ataactggaa ggtcgtattg aacgtttgtg ataacgtctg ggtagcacat
    28321 gttgaatgct ccgtcaccca tgatgttcca tacttggcga tctggattgt ctttcttagc
    28381 agcgatacca ccaggaaggg caatacccat tgtcgcaaag agtggagatg tacgccacat
    28441 gttcttaggt gtcatgtgaa ggtgacgagt agatgtttga gtagtgttac ctacgtcgat
    28501 tgagtagata gcgtcttgat cagcatgttt gttgattgca ttgtaaactt gatacaattg
    28561 caattcaccc tcagttttac cttcgagttt gttcatgtaa tcacgccagt tttggttgtt
    28621 cttaacgttt gcacgccacc atggagttga ttcaactggg tttactttgt caaggatagc
    28681 tttagctgct tgaccagcat caccaaggat tgaagcgtca agggcatgac gtttaccaag
    28741 tttgtaaggg tcgatatcga cttggatgaa tttttcagtg ttcttgaatg cttcgtaaac
    28801 ttcagcaaat gggaagtttg aaccaaggaa aagaactgtg tctgcttcaa agaccacttc
    28861 gttggctggt ttccaaccaa cacggtaagc agaacctgtc aaaccttcat agttccattc
    28921 gaaagcttca aagtttttac cagttgtgat gattggtgct ttgattttac gtgacaattc
    28981 agtaatcact tcaccagctt taacaccacc aaatccagca tagataactg ggcgttcagc
    29041 attgttcaag atttcaacag ctttgtcgat ttcaacttcg ttcaaagcag gagcgatgaa
    29101 tgagcgttcg tatgaacctg aaccgtagta tgagttttcg tcgatttctt ggaaaccgaa
    29161 gtttactgga atttcaacaa cagctggacc ttttttagaa actgcagcac ggcaggcttc
    29221 gtcaattact tttggcaatt gctcagcgta agctacacgt ttgttgtaaa cagcgatacc
    29281 gttgtacatt gggttttggt taagctcttg gaaagcatcc atgttcaatt cgttaactgg
    29341 acgtgatcca aggatcgcta ggaatggagt gttatccata gctgcatcgt aaacaccgtt
    29401 aatcaagtga gtcgcacctg gaccacctga accaactgca accccgattg agccgccgaa
    29461 tttagcttgc ataaccgctg caagagcacc tgtctcttcg tggcgaactt gtaagaagcg
    29521 gatatctttg tcttcagcca aagcgtccat caatgagctg agtgttcctg atgggatacc
    29581 gtagattgta tctacgcccc atgttttcaa tacgttaagc attgctgcag atgcagtaat
    29641 tttcccttga gtcatagtga taactctcct tcaatttttt tagacttgga gaatacgatt
    29701 acatagaatt ggaaacgttc tccaaatttt tactattcca ctgtatcata tttattctga
    29761 cttttctaaa aatctgctca aaactctcta ttctctattc taatacagtt ttgaaagtgc
    29821 tgtcatttct gttttacaac aaagaaatct agtcattact tttagtctat tttactaaag
    29881 tttaacagaa gagaactggt cagaacagat acagaactaa aggccatggc tagacctgcc
    29941 aattctggat tgagagccag tccaacacct gaaaagactc ctgctgctat cggaattccg
    30001 acgacgttgt agataaaggc ccagaaaaga ttgagcagaa tacgatgaaa ggttttctta
    30061 ctcatatcaa aggcacgcac cactcctagg aggttattag ttgtcaacac caaatctgct
    30121 gactcgatgg caatatctgt tccagccccc atggcaattc ccacatctgc tacactgagg
    30181 gcaggagcgt cattaatccc atccccaaca aaggctactt tgccagccgc ttgtagttta
    30241 tggatttcat ggactttttc ttctggcaag acgcctgcaa tgacctcttc aattccgatt
    30301 tgatctgcaa tagcacgcgc cacacctgca ttgtctcctg tcagcatgac tgttttaaga
    30361 ccacgttttt tcaactgact gatggctagc ttggcatttt ccttgggaat atcttgtagt
    30421 gcaagcaagc ctttgatttc attgtccaca gccaagaaca caactgtctt agcttctttt
    30481 tctaattgtt ctagtttttc ttgataaatg ctagaaatat ccatgccatc cagcatttta
    30541 gcatttccaa gcaaaacttg ttttccattg atttgccctg agacaccttt tccgtgcaag
    30601 gcttggaaat tttccacagt gtgaaactca agtccagctt cactcgctcg tttcacaatg
    30661 gcttcagcca atgggtgttg ggaagcttct tctagggagg tagccaatcc aagcacttct
    30721 gtctcgtcgc caataatatc tgtgaccaca ggtttccctt ccgtcaaagt cccggtctta
    30781 tcaaagacaa gagtttgaac tttctggatt tcctgtaaga cagttccatt tttgaggaga
    30841 acccccatct tggcactacg tcctgtcccc accataaggg ctgtcggtgt tgcaagtccc
    30901 aaggcacaag gacaggcgat aatcaaaacc gccactccgt agagaagaga ggacacaaag
    30961 ctagctccaa gcacgaccac actatccctg agcaagacga accaaaccca aaaggtcatg
    31021 attcctaaaa tgacaactac tgggacaaaa atccctgaaa tcttatccgt caagtcctga
    31081 atcggcgcac gacttgtctg agctttcttc acaaaatcta caatctgagc caaaacagtc
    31141 tctgagccaa ctttttctgc tctaaagaca agcgttccac tatgattgat ggttgagcca
    31201 atgacagtat ctccaactgt cttgtccaca ggcagactct cacctgtcac catggattca
    31261 tcaatactag agacaccttc tactacgaca ccatcaacag caatcttttc accgggacgc
    31321 actcgaatca ggtcgcctac cttgacttgt tccaaaggaa cttggacata actatcatca
    31381 ctcaagactt ctgcggtttt agcttgcaag tccagtaatt tctccacagc ttgggacgta
    31441 ttttttctca ttttttcctc aaaaactgct cccaaaagaa cgaaaaagag gataaatcca
    31501 gcactttcga agtaaacagg gagaccagca aagagagcaa ctaggctata gaaataagcc
    31561 actagagttc ccagcgcaac caaggtatcc atgttggcat tgtgcttttt aaaactggcc
    31621 caagcactct ggatatatgg cttacccgca actaacataa taggcgttgt tgctaaaaag
    31681 gttccccaat gcatgacttg atgactaatg ctacctgcca acatcccaat catgagaatc
    31741 acaagaggca cagtaaagat actagtaatc caaaaacgtt gcaggagaga tagagatttt
    31801 cgagtcttct caacgactat atagcttccc ttttgcatct tcatgccaca agaaaattca
    31861 tgtctcccta attcttgagg tgtaaaacga atgactttct cctcatctac gccgattgct
    31921 tccaagatac cttcttcttc aaacagaatt tccttataac agtttgaagg agtagcacga
    31981 tgaaaggtaa tctcagctgg aattcccttt tgaagctgga tatgggctgg atgatagcct
    32041 ttttcagctc ggatacggat tttttgaatg ccattttcta agcttgcttt cacaatttct
    32101 gtcatagtct ccacctactc tacaatcatc ttgccgtgca tcatgttcat accacaagca
    32161 aagccaaact ctccagcctg ttcaggcgtg atttccacta catactcttc ccccattggc
    32221 aggttcgcat gtacaccaaa atctggaaaa acaatttgat ccagacatgg tgaaggatcc
    32281 ttgcggtcaa agacaatgcg ggctggcact gatttcttga ggacaatcaa ctcaggagca
    32341 tagcccccca tgacttccac tcgaatctct tggtatccgt ttttttgctg ggctttttgt
    32401 ccagattttt caggcttttt gaaaaaccaa aacaagataa acgcgataag ggcaatacaa
    32461 ataatggtta caatactatt taacatggcg tctcctttac atacaattac atcttacttc
    32521 tgttacagca cttgatttct tctctgaaat cacagcttcc aagtcttcca agtcagtctg
    32581 agtaaattca cattctacaa tcaagtcagc caacaaattc ctaatcctac gggaacaaac
    32641 cttgtctttg atatcttgga caagtaaatc ccgactttgg tctagagtta aaagggctga
    32701 ataaacaaag gacttgcctt cttttttccg agtcaaacac tctttctcaa ctagacgagc
    32761 caaaagtgtc tgaaccgtgg acttggacca gtcaaaccgc tctgccaaaa ccctaatcaa
    32821 atctgtactg gtctgctccc cctgcatcca aataatcttc atgacctgcc attctgcatc
    32881 tgaaatctgc attaccatac ctccaaaatc tatatttgtc aattacactc aacagtatac
    32941 tctcaaaatc tacatttgtc aattatagaa ataatatttt cttcgaaaaa tagaatttta
    33001 atcatttgaa aaacgatttg cagtcaaata ttactatata aacaataaaa atatgctata
    33061 ctaaagaaaa aagaaaacaa ccactagggg tgcgtaaagc tgagattaac gactgttaga
    33121 tccctctgac tcaatctagg taatgctagc tgatggaagt ggaaatgata atggggacta
    33181 gcagtcttct attgcctttc taaaacagac tagcttgttc ttaagaatac aaacttcagt
    33241 tggttgggag gttttagatg acttatttac ccgttgcttt gaccattgca gggactgacc
    33301 ctagtggtgg tgctggcatt atggcagatt taaagtcatt ccaagcgaga gatgtctatg
    33361 gaatggctgt tgtaaccagt cttgtcgctc aaaataccag aggtgttcag ctaatcgagc
    33421 acgtttctcc tcaaatgttg aaagcccaat tggagagtgt cttttctgat actccacctc
    33481 aggctgtaaa aactggaatg ttggctacta ctgaaatcat ggaaatcatc caaccctatc
    33541 ttaaaaaact ggattgtccc tatgtccttg atcctgttat ggttgctaca agtggagatg
    33601 ccttgattga ctcaaatgct agagactatc tcaaaacaaa cttactacct ctagcaacta
    33661 ttattacgcc aaatcttcct gaagcagaag agattgttgg tttttcaatc catgaccccg
    33721 aagacatgca gcgtgctggt cgcctgattt taaaagaatt tggtcctcag tctgtggtta
    33781 tcaaaggcgg acatctcaaa ggcggtgcta aagatttcct ctttaccaag aatgaacaat
    33841 ttgtctggga aagcccacga attcaaacct gtcacaccca tggtactgga tgtacctttg
    33901 ctgcagtgat tactgctgaa ctagccaagg gcaagagtct ttaccaggca gttgataagg
    33961 ccaaggcctt tatcacaaaa gctattcaag atgcccctca actcggtcat ggttctggtc
    34021 cagtcaacca tacaactttt aaagattaag aaaaaaactc tctagttccc actttaaggg
    34081 aattagagag tttttatact cttcgaaaat ctcttcaaac tacgtcagct tccatctgca
    34141 acctcaaaac actgttttga gctgacttcg tcagtcttat ctaaaacctc aaggcagtac
    34201 tttgagcaac ctgcgactag ctttctagtt tactctttga ttttcattga gtattaatta
    34261 ggaaagaatg tcatgcaact ttgttaaaaa ggcttgcgtt tttgcctcaa tatcttctgc
    34321 ttgcatcaaa tcacgtacaa cagctacacc agctatgcca gtgtccataa gctgatcaat
    34381 attctctgat gtcaagccgc caatagcaac tactggaatg gcaaccgttt ggcaaattgt
    34441 tttcaaggtc gatatcagag taatgggcgc attttccttg gtggtggttg ggaaaatggc
    34501 tcctgtaccc aagtaatctg cacctgattt ctccgcttcc agagctcttt taaccgtttt
    34561 agcggtgaca ccgaggattt tttcaggacc caagactttg cgagctaccg aaactggtaa
    34621 ttcatcatct ccgatatgca gacctgctgc atcaaccgca agacaaacat ccaaccgatc
    34681 atcgattatc aagggtacct gataagcatc tgttatttcc ttgacttgtt ttgccagttg
    34741 ataatattga ttggttgtga gatttttttc tcgcaattgg actatggtaa cccctgaacg
    34801 gcaggccgtc tcaacttttg caagaaagct ttccacggaa tcttgatagc gattggttac
    34861 cagatatagt ctaagtgctt ctctattcat aaacctctcc tttgatggta tctagccaat
    34921 tttcatctct tcttaggatc gaaagctgat tgagtacttg gtaacgaaat tcttccaatc
    34981 ccattccttg aacaactatt ttctcagcag cgatattaag ataagagact gctaagcaag
    35041 aagcttcaaa accagtcttt ccttggctga gaaaaacagc tgttaaggct ccaaccaagt
    35101 ctcctgtccc tgttatccag tctaattcag tacagccatt ctccagtaca gcaacttgat
    35161 tctccgaaac aataaggtcc ttggggccag taactaagaa agacatacca ggataggtct
    35221 gacaccaatc tttcaagact tgaagcaaat cctccgtttc ttgatcttta gcactcgcat
    35281 cgaccccaac gccgtggtgc tttaaaccaa caagacttcg aatttctgac atgtttcctt
    35341 taaggatcgt agggctatag tctaaaaggt ctctgactag tcccttacga atgggcgacg
    35401 ctgatacacc aaccgcatct actaccatcg ggagagaaga ttggtttgca tacgaagctg
    35461 ccatgcggat tgctttttcc ttctcagctg acaaatgccc caaattgatg aagagagcct
    35521 gactttgctt agtaaaatca agaacctcac ggggatcatc tgccatgaca ggtttgcatc
    35581 ccagagccaa aatcccattt gccagcatct cacaagaaat ctcattggtc atacagtgaa
    35641 tgagggaact agagcctata ggaaaaggat ttgtcaatgc ctgcatcatt ctatcctttc
    35701 agcaaagaaa tatccttgca cttttttaaa gaattcctgc ttgattaaaa atctaaatgc
    35761 aataaaggaa atcgctgtac caatcaaggt tgctccgaaa aatcgaggag tgtagataaa
    35821 ccaactaagc ttagcagccg atcctgtaaa gagcaccata acaggatagg aaacaataga
    35881 accaataata cctgttccca caatttctcc caaggcagaa aagtaaaatt ttcgaccgta
    35941 cttataaaag agacctgcta gaagggctcc aaaagtcgct cctgtgagag ctaaaggcgg
    36001 aatcccttga gtcgtcatac ggataaaggc tgtcactgta gccatagcca aggcataaac
    36061 aggtcccatc atgattcccg ctagaatatt gactacactg gacatcggtg ccattccctc
    36121 aatccgaaag ataggtgtaa ggactacatc aagggcaatc atcatagata aaatggtcaa
    36181 tttgtgaact tgtagttggt gctttctcat gtttctattc ttctcctttt tctaaagact
    36241 gtaaatcgct cttccatgtc tggtgttggt aggccatttc ccaaaacttg gcttccatat
    36301 gaacactgat gtggaaggca tctagcattt tttgcttatc tgtctcatca ctttctcgat
    36361 agagctgatt gaccagtgct ccctcctctc tgatctgttg ctctaactca tccgtaatat
    36421 aagtttcaat ccattgttga tagagaggat ttggtgatgg tttaagatta agtgatttgc
    36481 ctatgtcatg gtataaccaa ggacaaggaa gcaagcttgc aaaagctatg gctaagttcg
    36541 gctctgcaaa ttgcctataa atatgagaaa tgtaatgata acaggttgga gcgattggat
    36601 gttgctccat ttcctggtcg ctgatttcca attccttgaa aaattgttgg cgaataaata
    36661 actcaccctc cactaaaccc tgagcatttt gtttcaagag tcttttcatc tcttggtttg
    36721 aagtcttatc agccaaaaga tgatagattt ctgagaaggc cttcagatag taggcatcct
    36781 gaatcaggta atagcggaaa atggcaggtt ctaaattccc ctcttgtaat tgtaaaataa
    36841 agggatgatg aaaggaagcc tgccaagctt tcttggataa ttccatcgca atatctgtaa
    36901 attccataat aactccttta taaaaataga ctggtttgaa gcaataaaaa gaaaagcagg
    36961 tagattaatt ttgttttttt aggaatataa aaagtccgat agctattctt caactgtgca
    37021 tgttcgtcat atccgtgagc agatagagct ctcaggtaaa gatggcgcca cctaaagact
    37081 gtcatcagaa ccttactgta aatcaagggc gaccaaaaat gtagttcttg accacgtaat
    37141 aggcaagctt ctttgaggga cttgatttct tgctgaatga gaggaaaaga attgaatacc
    37201 acaatcaagg cataggacca agagcgtgat agcccctttt gagccaagta caagagaagc
    37261 tcttttagtg aaatagagga aacaaagaca aggccgatac aaactgtcac aaaggccctc
    37321 gttccaagca tgactgcctg tgaagcatct ccgtgtaact gaactgccca gtagttggca
    37381 aaagatggta aaatggcaag tatgatcatc caagctaaca ttttaaatcg acggtaatag
    37441 agcataaaga gaatacaaaa tgcgactacc gaaagattca gagcaatcga aggaatgaaa
    37501 gatgtttcca aggataaaat cagcaagaag agactgataa tcggtgtctg ggttgctact
    37561 ttgaccatac tatctcactt ccccttgggt attgctactc tgagatgtaa gtggtttggt
    37621 aatggtcact tctttcacat gccgaagacc ctgactagtc atctcaatcc aataatcaac
    37681 cacagaaatc aaagggtcta aacgatgact aatgagcaga aaacttcttc cttgattcct
    37741 ctcctccaca atccacttgc aaaaataatg gcaggctcta tcatccaaac ctgcaaaagg
    37801 ttcatctagc aagatcacgg aagccttact ggtcaagatg gtcaagagct gaagaatttt
    37861 ttgctgacca ccacttaatt gatagggact cttatcgact gcctgctcca aatcaaaata
    37921 tcgtaaagct tgaaaaatcc gctgatttct ttcagaatca ggtccatcta attgaagctc
    37981 ctctcgcaga ctgactcgga taaactgctt ctcagcttcc tgaacaacac ccgtcagatc
    38041 acggtacaaa ctctttttct ttttcaggac tgtccccttc catgcaatgc gccccttata
    38101 cttttgaaat tgaagaatag agcgaaagag ggttgatttc ccgacaccat tgtcacccag
    38161 gatacaggaa atcccttgat agaatgtgaa atcagcaatt gaaaagaggg ggcgattacc
    38221 aagctcacca gtcacacggt tcatatggaa tagttccggg ctagaagcaa cttcctttga
    38281 agcaacctgt gtcatctcat aggaagggat ttgaaacact tcccttagtt ttccgtctct
    38341 tagctcaacc atatggtcga tataggcttt atagtcagat aaatcatggt cgcacaaaat
    38401 aactgtcttc ccatcaagag ccaactcttt tagaatctcc aatatctcga ttctgctctt
    38461 gcggtcaata gaagcgaagg gctcatccaa gagatagacc ctaggattca tggcaaagag
    38521 gacagccagc gctgcttttt gcttttcccc acctgatagg tgatgaatgg gacggtgtaa
    38581 gattgcctcg caacgacatt gctggacaac ctctgctatt ttagaatcaa tttcctgaag
    38641 gtgatagccg atattctcca aggtgaaaat cagctcctca aacaagttct ccatggtaaa
    38701 ttgatgattg ggattttgaa agagaatgcc aaccttctgg acacgtgcga tgatagaaag
    38761 ctgactgacc tcgctcccat ctatcaggac ttgaccacta tagggaagag aactgacttg
    38821 ggcaatcatt tgaaagaggc tggattttcc tgaaccactg ctcccaacta acaaggtaaa
    38881 ggcttgcgca tgaaaagtaa aatcaaacgg ctcagagaag attggggact gaatcgctcg
    38941 tagttccaga cccatctatg cttttcctcc agttgcaaac tgatgataga gtttgacaat
    39001 ggcacgaacc aagatggtac agaagaaata aacagaaata aaacgtacca caagcaagga
    39061 aaggacaaac ggaagggaaa aggcgtagta acctaactta atgtattcat agacaaagct
    39121 aacaagcgta atcccaatac tattagcagt tagagagagc caactttcat agcgattctt
    39181 agttacgata aaaccaaatt cacttcccaa accttgaacc aagccagaca aaagagctcc
    39241 tagaccaaat tggctaccat aaaggacttc agcaagcgca gctagcactt ctccaatcgt
    39301 tgcacttccg actctcggaa caaagatggc agcaatgggc gcagccatac accagagacc
    39361 gaagaggatt tcattggcaa aggcctgcaa accaagaggt gttaagagta gactgagaat
    39421 attatacaca tatcctgaac caacgaaaac cccaccaaaa aagatagaca agaaagcaag
    39481 caagataaca tcttttaact gccatttttt caacataaaa aaactccttt ttttaaagaa
    39541 aagtggggca ctcaagaaga ccgacctaaa tactttgtat agcagactga atttagaaca
    39601 gtacacaaga acactaaaat atttctagaa attaatttga attttctaat tgatttgttc
    39661 gcatcttatt tcaatctact atatcatctt catccagttt cgtaaaagaa aaaactctaa
    39721 ttacagatac gaattagagt tcagcttaca agattagaca gttcttttcg acatacgaaa
    39781 aaaacatttc acatttccct tcgccagtct taactgtatc aggttcaatg ggtatcatct
    39841 cagcctaaag caccccaaat gtctttatta tttaattatg tgattattat aacacacatt
    39901 ttatactagt tcaagaaatt gaactggaaa tacagccttg cactcacaaa gacagcagat
    39961 ctttcttttg caaaaaacaa atgacctgtt tgatgaatta gccattcaag ctgaatctgg
    40021 acatagcttt ctggacatag ctttttaaaa aaggaaaatc ctacttactt agaatccaag
    40081 gatagatatc tattgttcac tcatttcccg aacagttttt tctatatttt ttgcatacga
    40141 tattgccgaa atgattgaaa cgccatccat attggtcttt ataatgtctt taatatgttt
    40201 cgtctgtatc ccaccaattg caactaaagg catttgtggc aatagttttc tcatcaattc
    40261 aagaccttca taacctatag caccaccagc atcatctttt gactgggtat caaatacagg
    40321 cccaacacct acataatcta catattcaac ttttgattgt tgaaattctt cttcgtttct
    40381 tatagaaaga ccaattattt tatctggcat caattttcta atttcatcaa caccaatatc
    40441 atcttgacct acatgtacgc catcggcgtc aatttccatt gctaaatcta tatcgtcatt
    40501 aacgataaat ggaacattgt attttttaca aagttcttta atttggatag ctagctcaag
    40561 tttttctaag ccttctaaag caccctcacc tttttctcga aattgaaata aggttatacc
    40621 accttttaag gcttcctcaa cgactgtata tagatttttt ccttggcaag tagtcgttcc
    40681 acaaataaaa tatagtttta gtaattcttt atgaaacatc ttacttcact cttttgaatt
    40741 cctttacatc ttcatctgta atctcgtata aggcatttat aaattcaact ttaaatgtcc
    40801 caggaagatg tccatttgga cgtttttctg ccatttctcc agcgatattg taaactaaca
    40861 ttgctgtttc taatgatttt aattcttgac ctttttccag tccgataaaa cttgctacta
    40921 cagctcctaa taagcatcct gtcccaatga ctttcggcat catagcacta ccattatgaa
    40981 tcgttaccac ttctccatta acagcaatgg catccacttc acctgttact actattggaa
    41041 tattgaactt ctcatttgct gctagagcaa tttcgtcaat attatctacg cccgcactat
    41101 ctactccttt agatgccaca tctattccta ctaaagaggc aatctcgcca gcatttcctc
    41161 taatcgctgc tagtttataa ttgttgatta gatcatctgc tacttttttt ctatattctc
    41221 ctgctccaca ggctacagga tctaaaactg ctgggacatt atatttctcc gcaattttca
    41281 gagcagcttg gtataatttc caattttcat ctgtcaatgt tcctatgttt attaataaac
    41341 caccagcata ctttaacaaa tcctctaaat ctgctggaaa ctcactcatg gctggtgagg
    41401 cgcccagtgc tactaatcca tttgctgtga aattttttac tacatcattg gtgatgcaaa
    41461 tgaccaatgg tgctttttct tttaataatt ttaaacttgt catattgaaa tccttccttt
    41521 tcactttata cgatctactg atttcgattt atctctatct ttcgttaaga aatttttttc
    41581 atttacgttg aatgatttat actcaatgaa aatcaaagag caaactagga ggctaaccgc
    41641 aggttgctca aaacactgct ttgaacctgt agataagact gacgaagtca gctcaaaaca
    41701 ctgttttgag gttgtggcat gagccttctc tagacatcgt aaccaatatc aaaaaaagct
    41761 aattctaaag cgactgcttg attccagcgt tgctgaagtt ctgtcaaatc ttctcgattt
    41821 ttaccgacac gattgagttc gtcaaccaga aattgaaccc actctgcaaa gaaaggacct
    41881 ctgtggagat tgatccattc cgaatgaata tagacttcag gtagagccaa atctttagaa
    41941 ccccagtcta aatagagacc ttctgcaatg accagcataa ccaaaagatg ggcatagtct
    42001 gatgaagcca ctgccgaata cattagatcc tgaaaggctt ttgttacagg gtgcaaagtc
    42061 acttctagat agtcattctc tgctactttt aactctttaa aagccttttg gaaataacca
    42121 tcttcatctg cttcaagaaa gcctagttgc ttggcaaaac gaagcttgga ttcaagttta
    42181 tctgcgtgag ctacgcaggc acccagcatg gataagaagg catcaaagaa gtgataatct
    42241 tgaatcagat agtcctttaa gaccttattc tcaattgtcc ccgcaaaaag ttccttaaca
    42301 aaacgatgat tgattgcagc ctgccaatcc ttctgactgc tttttaataa ttctccaaca
    42361 gtcaaacctg gctgaaatgc atagtcttgt gtttccatat ttacttctcc tctctttact
    42421 tgttagtaat taataaaaca ccaagaaata tcaagcaaaa tcgtaattcc acttgatcct
    42481 tttaaagcac atcgagagca tttgcagaga gctaactaaa caagcctatc cagtttatat
    42541 aaacaaaaaa ctccaattac aatcaagaat tagagttgac ttacaagatt agaccgttca
    42601 tttcaccata cgaaaaaact gttcacattt cccttcgcca gtcttaactg tatcaggttc
    42661 aatgggtatt atctcagcct aaagcacccc aaatgtctct attatttaat tactgaacca
    42721 gtatagcaaa aaatgaaagc cctagcaaga tatttgaccg aaaaatatct ttatatataa
    42781 tatattgaaa ctagaatagt acacctctac ttctaaaaca ttgttagaaa tcgatttaac
    42841 tgtcctgatt gatttgtcct attcttattt cattttacta tagttttcga tagcgattta
    42901 ttcttccaat acacgaagaa aaacctccac attcagtgaa ggcaatctgt tttatcaata
    42961 caattttaag tcacgagggt caactgggaa ggttgggttg tatggattgt gacggagctt
    43021 aaagtgtttg acatcttcaa tggtctgagc tccagacaat tgcataactg tcttcaattc
    43081 cgcattcaag tgttcaaaga cttgacgcac accgacacta ccaccgagag ccaagccata
    43141 aataacaggg cgaccaatag ctaccaagtc tgctcctgaa gccaaggctt taaagacgtg
    43201 ttgaccacga cgaacaccag agtcaaagac aatcggcaca cgtctatcaa ctgcttctgc
    43261 cacttcttga agcgagtcaa aggcagctgg tccaccgtcg atttgacgac caccgtggtt
    43321 ggttacccag ataccagaag ctcctgcagc aagtgaacgt tcaacgtcct cacggcattg
    43381 tggtcccttg acatacacag gaagaccaga gtattcagcg ataaattcta catcgcgtgg
    43441 agacaagcgt tgtttagctg atttgtaaac aaagtccatt gatttaccag caccttctgg
    43501 caggtattct tcaacaatcg gcatgccaac tgggaagaca aaaccattac gcttatccac
    43561 ttcacgattc ccccctacag tagcatctgc cgtcaagaca atcgctttat aaccttcagc
    43621 cttcacacgg tccatgatgt ggcggttgat accgtcatcc ttactaaagt aaaattggaa
    43681 ccaatggggt gtcccttgaa gggcttcaga aatctctgga aggtcaacag tagagtaaga
    43741 gctggttgta taaagagaac caaactcatg cacaccacgc gcagtcgcca cttccccctg
    43801 ttcatttgcc aatttatgag ccgcaacagg cgccataatg attggtgaag atagtttttc
    43861 acctgcaaat tcaatctctg tacttggatt ttcaacatcg caaagtgtat gaggaacgat
    43921 gagtttgtgg ttaaaggcgc ggatattctc tcttaaagtg aaagtatctt ccgccccact
    43981 agcgatatag ccaaatgctg ctttaggaat aacttgttgc gccattggct ccaaatcata
    44041 ggtattgatg aagtctacat gaccttctgc attgcttgtt ttgtatgaca taaaatgccc
    44101 tccttgatta agtaagcgtt tgctttttac tacacaacta taataactct tttttcaatc
    44161 attttcaaga gttttgctta aaaaccatct tattttttca tacaatatac tagccctact
    44221 ttccttaaac tctaaacttt agtctatatt aagtgaatcg ttgagatttt ttgctgccag
    44281 gcatttgaac tactttttta tttgctgatt ctatctacta atactataaa aaacaagtga
    44341 ataagacacc agaacatcct ctaataggac ctatggactt atatcagtcc catatatact
    44401 gtttaagcaa gatactatcc tagttgacgc taacttccta tcccacttat taatttttta
    44461 tttatagtga atctgaacaa atcaattggg gaatccaagt caatttctag tactttttga
    44521 acagtttcag cgtactatcg taaaatgaaa taaaacatgc acaaattgct tagggaattt
    44581 aaaccaattt ctaacaatgt cttagaaatc aaagtgtact atttcaactt caatatacta
    44641 cacttcattt tctccttaaa ttcagtctct ttttgaatca aaaaatcctc tggtaagagc
    44701 cagaggataa gaatttattt cattgttggg aagagcaata catcacggat agttgttgta
    44761 tcagtgagga gcatgcagag acggtcgata ccgattccca aaccacctgt tggtggcata
    44821 ccgtattcaa gagcttcaat gtagtcatag tcgattcctg tcgcttcatc atcaccaagt
    44881 tctttggctt tagcttgggc ttcaaaacgg ctaagttggt cgattgggtc gttgagttca
    44941 gtaaaggcat taccgtactc cttagtcatg ataaagagct cgaaacggtc agtaaagcgt
    45001 tggtcttcag gatttttctt agcgagtgga gatacagcta ctggatgtcc atagacaaag
    45061 gttggttgga ttaaagtttc ttcaacaaac tcttcaaaga aggcattgat gatgtgacca
    45121 acctcagtgt agtgtttctc aactggaact ttcttctcag cagcgatagc tttagcttct
    45181 tctaaagtca tgtcttgcca gaaatcgaca ccagtaattt ctctgatagc atccaccata
    45241 tgaacacgct taaatggttc gttaatcttg atttcagtac cttggtagtt gactgggcca
    45301 tcgcccttaa ctgatttagc agcgtgttgg ataatgcctt ccgtcaagtc catgatgtct
    45361 tggaagtctg cataagcttg gtaaacttcg atagaagtaa actcagggtt atgagtagcg
    45421 tccattcctt cgttacggaa gatacggcca atttcataga cacgttccat accacccacg
    45481 ataaggcgtt ttaagtgaag ctcagtcgcg atacgaagca ccatgtcaat gttttgggca
    45541 ttgtggtggg tgataaatgg acgggcagca gcaccaccgg cttcattatg aagaacaggt
    45601 gtttccactt caaggaatcc tttttggtca aggtaacgac ggatttcaga gatgattttt
    45661 gaacgagtga caaagcgttc aaagctttca cggttagaaa tcaagtcaag gtaacgttta
    45721 cggtaaattg tttcaacgtc tgtcaaacca tggaatttct caggaagagg acgaagagcc
    45781 ttagacaagt gtgtgatgtg ggttgccttg atagagagtt ctcccatatc cgtacgcatc
    45841 acttcacctt cgacaccaag gaagtcacca aggtctgctt ttttgaagat ttcgtagttt
    45901 tcttcaccga cagcatcctt acgaacgtag atctgaatct ggccttcgcg gtcttgaagg
    45961 tgggcaaaac caacttttcc tttaccacgt ttggttacca agcgtcctgc gatagtagct
    46021 gtttcgtttt tatcgtgtaa ttgttcttta tcgaggttgg catatttatc ttttaattct
    46081 tgtgaatttg cagtacgttc aaaacgtttt ccgaaaggat cgattccttg ttcgcggagc
    46141 gcagccattt tttcacggcg aacgatctgc tggtcattta gttcttccat atgttctgta
    46201 gacatgggat cctcctagtt ttactcaaaa ttgaatacga tgagtcattt tttgcgatac
    46261 tcccatttta tcataaataa gcaagaaatt cacggataat ctttcaaaac taaaaagaat
    46321 ttgacgccaa gatcactgag ccaaatcact gaaaagactg ggataagcaa gaaattccaa
    46381 aatctcagaa aaggaacgac tgctgagact tattttgaaa agaatcatcc agaaattaaa
    46441 ctccaaaaat atgaccaata cagtgactct taccaagctc ttcttgacgg acgtggagat
    46501 gccttctcta ctgacaatac tgaagttcta gcttgggcgc ttgaaaataa aggatttgaa
    46561 gtaggaatta cttccctcgg taatccagat accattgcgg cagcagttca aaaaggcaac
    46621 caagaattgc tagacttcat caataaagat attgaaaaat taggtaagga aaacttcttc
    46681 cacaaggcct atgaaaaaac actccaccca acctacggtg acgctgctaa ggcagatgac
    46741 ctagttgttg aaggcggaaa agttgactag tcattaactc ttaaaagggg ctggatttta
    46801 agctccaatc cctttttaag attttaccta taacatcctg agtctatcta agatgttcaa
    46861 tctgaacaca gtgtacatac tttatcttct attgcatata ctttatcaca taagatacga
    46921 atatcctctt cactatgact agcaatcaaa attgttgtcc ctttttcact agagagcttt
    46981 ctaaacaatg ttctcatatt ttctacactt gatttatcca aggcattcat aggttcatct
    47041 agtaaaagaa tagagggatt ctccataatt gcttgagcaa tccctagctt tttcctcata
    47101 cctagcgaat aagttttaac tttctggtct ttttgctcat atagaccaac tattttcagt
    47161 gtatcattga tttcctgatt accaactact cctcgtatgc ttgccaaata ttgtaaattc
    47221 ttaaagccac tataataatt tataaaacca ggttcttcaa tcaaagctcc caaattagct
    47281 ggaatttttc tctcaggaac aatattttcc ccattgatta acacttctcc ataagacgga
    47341 ctatataaac cagctattaa tttaaacaat acacttttcc ctgagccatt cgcaccagta
    47401 attcctataa tttccccctg tttacaacta aagttaaggt tttgaaaaac acatgttttt
    47461 tttaatttca actcaatatt ttttaatgta attatttcat tcattctata aacctcctct
    47521 tttgacgagt gaaatagaaa atgcttttaa aaagaaagac taaaaatagc aactgaagaa
    47581 ataaatctcg tcctatatct ccattccctc gattcaaaat ataaaataga taattagttc
    47641 gatttcctac aaatagacca ccaaacacaa tcatgagtaa aaagaaacta acgcaagcaa
    47701 agttcatttg tacattcgct cctagtgcgt ataacataaa gcaaagcaag gatagcacac
    47761 aagcattcaa agaatcaact ataaacaaaa ctcctatatc ccagtttggt aactgtaaca
    47821 taaattgaat cactagaact tttaccatga ttaaaataag tccataaaga aaacaggtcc
    47881 aaatctgata cctaatccag agcttaatag aagaaaatcg aatcacttcc agaaagaaat
    47941 cggatgctct tctacgatat acaactacta gaaaaaatgt atgaataata aaccaatgaa
    48001 gcaaccatat agataagact aaaaaagagt tttgactcag attaggccct tttaaaattt
    48061 ctataacaag tctatcattt ccttctaacc aataccataa tcctaaacaa atcaatatcc
    48121 aaaaaagaac ataaccccaa aagtacttgg catagattat ctgattcaac ctccacatgt
    48181 gactacttaa ctttcccatt tccaactttt acactctcct ccagtttcta tgaacagaaa
    48241 atacagtcaa tggaattatg atagatagta atgtaagcca ataaatcaat gcatacggat
    48301 tggaatttac catatactga aaaattggca ataatccaat tatcccattg ttcaactgat
    48361 aaatccagaa taaggattct acaaataaaa aagtaaacag aaatactaag ctcatgtttg
    48421 attttttaaa ccaagaaaaa ctgctaatag taagtaagga taaaaagaaa tagtatgcta
    48481 tataagagaa aaaaaatcct ataaagaaac tagcattgtt tgcaatactt ataccataaa
    48541 attctcttaa aaaatcaacc tcctttatct ccaaagagaa gctaaaacca ttactaaatg
    48601 caattagaaa aatcaataaa aataaagtcg ccgtccaaat ccccgtacta agagctgcta
    48661 atttgaaact aaaactggta aagtgcttaa ttgatttcag acgaatgcga cactccaacc
    48721 tattaaaata gttattcatc aaatgaaaaa agaacaatat atatgtgaac ggaaagcaat
    48781 atactccagt cgtcatatct tgaagtaaaa ctaagatcca ttctaataca tttggatgga
    48841 ttgaatattg gcgacagcgc aataaatata ctgtactaga taaaacacag gatagcagta
    48901 atataaaata aaccaatact gctaagaaat cttttttata aaattgaaca aattgtttca
    48961 ttatacatag tcctctgaat gtagaaaaaa tgtaccataa acaaccaaac aactaacaaa
    49021 taaaataaaa gcaagatgcc cactaactaa ggaaagactg atatctttct gatatcccaa
    49081 agctagcgtt gtcacaggtt ctaagtaaga tagccctaaa atagcccata aaataccacc
    49141 aaccatcata taggcaactg ggatgaaaat agctcctaat tttttcttca ctagcaaagc
    49201 actagctagt ccaaaaatag agaacacagc gccccaaact ccataccaga gagtcgtcac
    49261 aagactatag agaaactgat tagaatcaaa taattctttt aaggcaccac tataatctcc
    49321 aatataaatt tcctgataag gagtcactaa aagattaatt cctaataata ataaataggg
    49381 gagaaaaaag actagaaaag aagaaataat tgcagtacta cctacaatag ctagatacct
    49441 ctttttagaa attcggcaca attgtgctgt tagaaaataa ctctcagcat cctctattat
    49501 ctgactagaa tagggcagtg tacagataag tgcagctact aggctaatcg gtgaaaatcc
    49561 tcgaatagaa gaagcggcaa aaaaaatcga taaaacttca attttataaa taccattgaa
    49621 agcaaggaaa tttcctaaac tcatgcaaag aagggtcaaa aataaagaca tataaaaccg
    49681 aggtgattga acgactcgta caagattaca aatgaaaaat tccatcctta ctcctcctta
    49741 taataaaaat agggtgtagc attctttttt catgctacac ccacaatcaa ccatctttaa
    49801 ggcttactct gacaagtaag ttaataagaa tctggactcc aagaacctga agtatgaatt
    49861 cttacatgat ttccaaattg tggcgccata gctaatctag taccagaacc aatataattg
    49921 tcaccacctc cattatagta catgacaatc ctagagccag accccaatga atataccggg
    49981 gtaatatctg acccactata ggcgctacga atagaggtat ttaacctttt accgccacca
    50041 gtgctgtcac tattattaat tccagcagag gcgttttctt tctcaagctc actagttgta
    50101 tccgaacccc aacgcggcaa cgttaaatca taatttccaa tctgtctagc taaaactgta
    50161 gggagaaaca aactagatgc aattgtaact acgcaaaaaa ggaatatatt tttcttcttt
    50221 tcatgacatc gtcctcctaa gaagtgataa acaagatagt taattgatca atttgataca
    50281 tattacattt tcattatatc aataaaagaa agcgttgtca attatttcat ttaaaatatt
    50341 gtcatatttt aaatgaaatg gtaaaagagg ctcggtagcc tcgtctctct ttatcttact
    50401 gacctaacct tcttgccaat tttcttggtc ttctttaaag cgttttagaa gatcaaggcc
    50461 ctctggcgtg atgtaacctt cttcttgggc tagatggata agctcgctat agtttgaaag
    50521 cgtcacaagt ttaacaccag catctgcaaa gttcttatct gcttttggca attggtagct
    50581 gaaaatcgct acaactccaa gcacatctgc tccttctcgc ttggctgctg ctacagcttc
    50641 aagaactgaa ccacccgttg aaataaggtc ttcaaccact accatttttt gaccttgagc
    50701 tacgcgacct tcgatttgat taccagctcc gtggtctttt ggtttgctac ggatgtaggc
    50761 aaaaggcaag tccatcttat cagcaataat ggctccgtgt ggaatccctg ctgttgcagt
    50821 tcctgcaatc acttctactt caggaaaggc ttctttgata gcttccacaa aaccattttc
    50881 aattagggta cgagtttctg gataggctag tgtcacacga ttatcagtgt aaatcggtga
    50941 cttgatacca gatgcccaag tgaagggttc ctctggtttg aggtaaacgg cttggatttt
    51001 caagaggtgg ctagcgatat ctttagcaag tgtcatggta ttctcctttt atttttctaa
    51061 tctagttctt taattccagt cctgtgtcca ttcatccttg atggcatgat aagctgcaac
    51121 aggatcctca gcttgggtaa tgggacgtcc cactacgata tagtcactgc cgatttgata
    51181 ggcatcagca ggtgtcatga ctcgtttttg atctccaact gcaacaccag ctggacgaat
    51241 ccctggtgtc agacagataa aatctggatt ggtagcctgc ttgatgactt gtacttcctg
    51301 agccgagcaa acaacaccat ccaagccagc ttcagctgtc ttcttggcat agtgaatcac
    51361 agactcttgc agactggttt ggatattttg aaactcctgc atctgagctt ctgacgttga
    51421 tgtgagctgc gttacagcga tcaatttggc ttgactccca agaccttcac gcgccgcctt
    51481 catcatctct acaccaccag ccgcatggac attagtcata tcgacaccaa gctgagacaa
    51541 gaccttcatg gctgacttga ctgtattagg aatgtcatga agtttgagat ccaaaaagac
    51601 actatgaccc aaacctttta agtaggacac aatctcaggc cccgctgcgt aataaagctc
    51661 catccctacc ttgagataaa ggctttcttc tgctgggaaa agagctaaaa attccttgac
    51721 cgcctcaaaa ctaggaaaat caagagcaat gattggacga tgttctcgca taggtttctc
    51781 cttttgcctt tactagtgag agagtctggc caacagaagc cacgaaaaaa ggaacctgcc
    51841 aacagcaagg ttccacgaaa aatgggtagt ctccaccctt tcaccgtcta accttagctg
    51901 cctctctgga ctgctttaaa ggttttttac tattctatta tttctactag cacttgtcaa
    51961 gtaaaaacag ctaaatccat gttgactgct attgaacacc tcacaagact ctttccaaaa
    52021 gaatagttaa agactttcac ttcggacaga gaaaaagagt ttgcttgtta ccctttaatt
    52081 gaacaaatgg gaattctgtt ttattttgcg gatgcctatt catcttggca aaggggaagt
    52141 aatgagaatg cgaatggact tcttcgtgag tattttctta aaccgatttg gcaacaatta
    52201 ccgaaaaaat ccttaatgat gctttgctag cttattaatc accgtcccca aaaatacttg
    52261 gattacaaga caggttttga agcacttata gaggagattt aaaaatgttg cattttttat
    52321 tgcaatttat cagttatctt atcacccaaa acttctgcaa ttagtatgag cactattgtt
    52381 atttttcttt tttcgtacac tcaaatcaaa atatagcaat aagactattc tgtagaattg
    52441 ctgtcaaaaa gatcagttca ttttttcctt cccacttgtg tttataatca ttaaaataac
    52501 tcaattaaga aattttcttt ttcctaatag ttatcgtaat taaagttaat agaagaacaa
    52561 tccaaataag tagtgttaga ttaggaatta gagttttatt ccatgaaaat tcctcccatt
    52621 ttgtgaaaaa cttagtaaat agtcccataa aactataatc tgttatcttc gcaactgtct
    52681 tatccaaacc agatagcatc ggtaagaaag caactaaaat catagcagga agactgataa
    52741 cctgagctac tacttggctc ttcgcggtta aacctatcaa taaatagaat aaaatgatgg
    52801 ataaagaggt tagaagaacg attgtaatat aattaaaagt atgtacaatt gtaactccta
    52861 aaataagagg agtagttccc ataatcacaa aagttagcaa aaaaggaaga aacatagttg
    52921 ataaaatgta ttcggagcct ttaacaccac tcaacagaag agtttgtaaa ttgtactttt
    52981 ctttctcttc agacaagata atagttatag gacttccaac agccaaagcc aaagaaaaag
    53041 gtaaacacat catcaaaaga actaatgcct gttgatcgtt gaccttcccc tgtgtttcca
    53101 taagatattt ataaaaatat gtgaaagcaa aaggcactaa aacttgcaat aaaatactct
    53161 tattggaaag gatgatttga caacgcaacc ataccaaagc cagaaaccgt ttaagcattt
    53221 agctttcctc ctgttaatgt gataaaaata tcttctaaag taggctcaca tgaatgaatt
    53281 gaaaaaatat tttccagatc agcctgagat acctgttcta gtgatgtaaa atcaaaagtt
    53341 atctgattcc cattataatc tgtaacctta atctttttat ctttattata tctttgaatg
    53401 agttcagaag gagctccttg ctcaactaat ttccctttat ttaataaggc aacataatca
    53461 cataaaagac ttgcttcatt catatcatga gtcgttagaa aaatcgttgt ccctgctgtt
    53521 ttcaattcta aaattaactc atgaattgtt cgagaagttg tgggatctag acctgaggtc
    53581 ggttcatcca gaaagagtac agcgggtttg ttgataagag ctcgtgctaa aagcattcgt
    53641 tgcctcattc cagtggataa ttttcctgct accatcttgc gactatcata taatcctact
    53701 cgctttaaca aattatcaac acgtgattta ctaatattat aaaatttact ataaaaaaga
    53761 agattgttat acagagacat tttctcataa aatccacttg tatcgctaac caatccaatt
    53821 ctctttaatt caccgcttgt taaattttga gatttttgtc ccaaaataat agattgtcct
    53881 ttatcggcaa ggagctgccc agtcagaata ttaatcgttg tggtctttcc agaaccagat
    53941 ggtcctaaaa atccaaaaat ctgaccttct ttaacagtga aacttatatc atttaaagct
    54001 attttatcac caaaactttt tgataaatgg ctaacttcaa tcatactcat tgcccctcct
    54061 ttatattcta catttttact taacatctat ttacttagct ttatcaaata aacgtcttaa
    54121 aaaaaacaat aacattaagc atataaccgt tagcaagatt gtttcaatat tattgataat
    54181 atgatacatt ctcaagcagt ataaaataat tatatatatg caaatgctca ttatacctat
    54241 ttttttaaac atactaagcc tccttgctaa ataataaagt tatataataa ctaagacaca
    54301 ctatacctaa cataataaat atccacagca ttaaaaatat tatcatacta ataaaaatat
    54361 ccactggtaa ctgaataaat gttctaaaat taacaagcaa aaataaaatc tcaaacgatg
    54421 aaaaaagcca tactatattt tccaatgatg tttgaatatt tttattgtag taagcataat
    54481 atatagcaaa aataataccc aagaacaata ctattaattg tgtttctata acagtgaact
    54541 gcccaatagc agataaaaaa gctactcctc ctgataataa gcaaaaacaa actgaacgaa
    54601 taaatgtttt cgctctaata ttgttatctt tcactttatt atttttttta caaattggac
    54661 attctccgtt ttccagaaca tatttttctt gacttagagc atgatttctc atattataaa
    54721 cgtaagcgtt atctattagg atttcattat aacatcccag aaatatttta attattaaat
    54781 tagtcattat ccctcccaaa atagcaggca tctctggtgt agtcggccac tttgtcttat
    54841 cagataaagt gtacttattt atatctttgt ttatattccg acaagcaaag caagaaccga
    54901 tggtagggat atatatatta tcaataataa gatagcatcc attaaaccct cctgatatgt
    54961 aggatatctt atgcgataca gcaaattgat tgacaatttt tataatatca atgggcgtat
    55021 caattgcttt aacgataaaa tctatactcc catattccgc aacaatgttt tctaattctt
    55081 ctactgaaga aactttaata gaaataggta ctacctgaac atctgaatta tacttgtgta
    55141 ttttttgaga aagaacatta atcttctcct taccaacatc cgactctgta taaagaattt
    55201 gcctatttaa atttgatggt tctattatat cgtaatcagc gacaataagt ttcctcactc
    55261 catacatact tagacttaga gatatataac atcctaaggc tccggctcct aatactaata
    55321 ctgttttatt ctgtatttta ttatactctt cattataaaa taacgaatag taacctttag
    55381 ttctagaata tctactatca atatctatct catccgaaat taaaatttgt tcatttaata
    55441 gttcaaatgt tagtttacta cctaatactt cttctatctc taatagttcc ttacaactat
    55501 taaatagatc gttgataaat tcttgcgaaa tttgaggttc tatagctatt tcccgcatac
    55561 tccgaccacg caaatacatt ataccttctt ttttataagc aaaaacataa ctatttacgt
    55621 agaacatatt tcgtccttcc tctcatatat aatatagaaa gcagtataga aacaactacc
    55681 cctcctatac tacgaacaat aatattaggt gtcaaaaatt gtaatagttg actcaaaggg
    55741 aaataaataa taacaaatgc tattaaaagt tgaactatat attgaaaatt caagttatta
    55801 ttgttagaat tcaagtatct taaaataata ccactatcat actgaaaaaa aggaattgaa
    55861 ttaataaaaa tcatacctaa gttaatgata aaaaataaga gtccaagcaa tttatacgat
    55921 gtgaacaata aaacaagtaa acctgtaagt gataaaatcg aatttgaagc aattcctgct
    55981 aacataattt tcaaaaattg ttttttattt tttaggaatt gcaccccact taaatctaca
    56041 aaaaaagcca aattaaacaa aagtagcatt attccacaat ttgggatctc aatttgataa
    56101 ttattagcaa ttattgcatg actaaattca tgtatcgttg cagatataat aacaacaagc
    56161 aaccaaaata aaagaatgtt tagcgttatt ggaaagtttt ggaaattagt caaaatatcc
    56221 gccctataaa tatacataat aaaacattgc aaaataagag ccaatgggaa aataccaaat
    56281 aggatttttt caaaattctt attaaatctt ttatagttta atttttcaga taatgttata
    56341 ttaaagtccc aagatatttt aaaaatattt atcttttttc gtgatttcat agaatctata
    56401 agtcccattt tactaagaac aatataaaat cttaaataat atttcttccc tactaacact
    56461 aataagtccg atatggtaaa ttcttgacct attagttgct ctaaccattt tttttcctgt
    56521 ttcccaacta atacatgttt cttactggat ggtatatata gatgatactg tccctcataa
    56581 ggagtaggta atatcttaat cttatcaaca attctcataa caaacctaac atttaataaa
    56641 taaaagaggg gctaagtaaa acatactcta gtccctcagt ccgcaatcaa taaaataatg
    56701 actaattcta ttaatctctt gctgcaagac taatacggaa aattcaaatg actgtctaaa
    56761 atgaaattga aaaagcttga tattagtaag tgaacaaact tcaacaacca gcaagagcaa
    56821 ggattgctaa accaaatccg atacctgttg caagtccagc tgaaaaatca ctaactggta
    56881 ctgaaatttc ttcaatttcc tcaaataaaa agttatcttg catgattatc actccctatc
    56941 tttttaacaa caggctactc caattaagag aactacccca gttccaagta aaactccccc
    57001 ccaaaattca ccatctgtag gggctacgat ttcttcaatt tcttcaaata agaatacttc
    57061 atctgacata tgtgttacct tcttcataaa aaattttttt gtaatcgatt acattgcaaa
    57121 tataacataa agaaaaacag atgtcaaata ttaaacgtaa aaacatggtc actaaataac
    57181 tataagagaa aaagtaaacc tagcgacgcg atgagcgctg ggtcgtttgg tttcgattgc
    57241 tctcttcctc ttgttttttc tgttcttctt cttgtttttt ctcagcttcc ttggcctctt
    57301 gtttggcttt ttcctcagcc tccataatca atttatccgc cacagtgtaa ctgtaaattc
    57361 cagcttccat gtcgaccaca ctcggttctg acaattgtgg cttaatctta ctgtaatatg
    57421 gcagtttctt actcatttca gatagaggaa ccaagacttc gtccgaatca ttcatggtca
    57481 atcgaattaa atcggatgtc accttgcttg gggctaattc caccttttgg atagccgcct
    57541 tgagttctgg gctaatttga gcaagttctg agacaaaaac cttgatttgt tcactatcat
    57601 taaagagaac tgataaataa gtttctggta aactgttcag actcacagaa ctagtctcaa
    57661 gctgaccact ggaaagaata ggataatgat tttcaccaga aatatagtag gccacaatat
    57721 catattcctt gaccttaata gtgaacttag ttggaaattg atagacaagt tgagctgatt
    57781 caacccaata gttagactta atctgctttt catattttgc cttgtctagc agaaggttaa
    57841 tcgtataatc cgaatcctga atgcctgaag cctgtcgaat atcatcagct gtagtttgca
    57901 ccgttccctc aacacgaata tctttcatgg tcgcataagg actgagcaag taggcagaga
    57961 caatcaataa aagcagactt ggaaataaaa tcgtgaaggc tcgcaagata tggataccag
    58021 gaatctttgc tttggctggt ttttcctttg tagccttttt agcaagcttt ttatcctgtt
    58081 cctccttctc tttagactct ggttcttctt tctcttcttt ctctttgtca gcctctgagg
    58141 atgctacttt ttcttcagac tcttccttag ctgattctga atcttcctgg tctgtttcac
    58201 tctcctggtc ctgtttatcc tctgacttct cagattcttc tcccattcga gcttgtcttt
    58261 ccttttcctt ctcctcagct agagccgcct cttcttcagc cttctttttt agatattctt
    58321 ggtttcgttt ctgccattct gataactctt tcaattcttc gagggtttct ttgtcctcat
    58381 ttttcttatc ttttgacatt tactttcctt atgataaatc ttttttcaac aattgataaa
    58441 aatctgctag agatttcaat tccttagaag ctttcatctt agcttggtaa tcttccttgt
    58501 gacttagtaa gtgagaaagc ttctcttcca aactatccaa ggtcaaatcg ctttcttgaa
    58561 ggtcttctgc atagcctttt tttacaaagt aagctgcatt ttcaagctgg tcaccacgac
    58621 tagcttcacg accaagcggc acaatgacat gcaattttgc tatcgccaag agctcaaaaa
    58681 tcgtattggc accacctcgt gtcacaacaa tatcagccaa ttccatcaag ggttgataga
    58741 gatcggtcac atagtcaaca cgaaaaagat tttggctcaa ctcattcagg ctagaatctc
    58801 cagttagatt gataatattg tagcgctctg ttagttcttt cttatggtct gtcaccaatt
    58861 ggttaaagac acgagcacct gcagaaccgc caacaaacaa tacagtcggc aatttatgat
    58921 taaagtggct ttgaatatcc accaattcat ctggttctgg atttttttga tctgaaacct
    58981 tggtcactgc tcccacatgc tcaaccttag acaaactcga agcttgctca aaggttgaat
    59041 acatcttagt cgcaaattta taggcgattt tattggccaa gcccatagac aggtcagatt
    59101 cgtgaataaa gacaggcact cctgacacac gcgcagcgat aacaggcggt actgagacaa
    59161 agcctccctt tgaaaaaagg gtctgtggac gaagtcgcaa catgataaag agcgattgga
    59221 cgattcccca gccaactttg aagacgtcca gcatattttg ccaagagaaa tagcgacgca
    59281 atttcccagt cgcaatggag tggaaagtga catccaaacc tgacttaagg atttcttggt
    59341 gttcgatacc acgcttgtcc ccgatatagt ggacttccca accatcttcg atgaacttgg
    59401 gcattaacaa aagattgagg gtaacgtgtc caaccgtccc cccacctgta aagacaattt
    59461 ttttcatatt ttattctttt aactccgcta ctgtgtcgat aaagaggtcg ccacgtactt
    59521 caaagttagc atacatatcc cagctggcat tggcaggact aagaagaacc acatctcctt
    59581 gagtcgcaag ttcataggcc ttgcgggtcg catctgcaat atctgtcgcc tccacataag
    59641 cgacaccagc cttgtctgct gcccgtttga cacgttctgc agattgaccc aggatgacca
    59701 tcttcttgag tccagtaatg tctggcacca attcgtcaaa ctcattgcca cggtccaaac
    59761 cacctgcaat caagacgacc ttgctgttgt caaatcctga taaggctttt tgagtagcca
    59821 agatattagt tgatttactg tcgttataga atttaacacc cttgatgtca tccacaaact
    59881 ggagacggtg tttgacacca ccgaaggctg aaagagtttc cttgatggtt tgattgtcca
    59941 caccacgaag cttggctaca gcaatagtcg caagggcatt ttccacattg tggctacctg
    60001 gaacaccgat ttcattcact gccatgacta cttcaccacg gaagtagagt tgaccatctt
    60061 ccagataagc tccatcaacc ttttcaagtg ttgaaaatgg tacaacagtg gcttctgtct
    60121 tggaagccaa gtcttttgcc aagtcttgat taaagttcaa gacaaggaaa tcagctgctg
    60181 tcatcttgtt ctggatattc cacttggctg ctacatattc ctcaaataat ccatgataat
    60241 cgatatgagt tggcatgagg ttggtaataa ccgcaatctc tggatggaat tcttgaacac
    60301 ccatgagttg gaaagaagaa agttccataa caagcgtgtc cttatctgat gctatttgag
    60361 caacctgact ggcaggatag ccgatattcc ctgataaaag accatgttgc ccagcagcag
    60421 tcaaaacttc cccaatcata gtcgttgtgg ttgtcttacc gttcgatcct gtgataccaa
    60481 taatcggtgc ttctgaaatc aaataagcca attccacctc agtcaagact ggaattccct
    60541 tggccaaagc cttttcaatc atgggattgt tgtaggggat acctggattt ttcaccataa
    60601 gggcaaactc ttcatccaag agttccaaag gatggccacc tgtaatgacc ttgatccctt
    60661 cttccagcaa actttgggca gctggattgt cctcgaaagg tttcccatca tttactgtca
    60721 caatggtacc tagcttgtcc aacaaacgag ctgcagattc accagacttg gccaaaccta
    60781 aaacaaggac tttcttattt ttaaattgat ctattacttt catgtctcga actccatttc
    60841 tactcctact attttaccat ttttatggaa ataaaaaagc cacaaagtgt gtttgtgact
    60901 ctttcttcta actgaatctt accatatcat ctatgtgata aatcggtaac tcgaatgacc
    60961 tgatccactt gctcccaaat cagaggatta tgggtcgcaa taataatggt ccgattcgga
    61021 ttttttaaag attctaggat ggaaagtaat tcctcagagt ttttggggtc taaggaagcg
    61081 gttggttcat ctgcaaggat caaaggtgga tcctttaaaa ttatcttcgc tagtgcaaca
    61141 cgttgtgctt ctcctcctga taactcaaat ataggttgct tcaaatccaa ataagagagg
    61201 tttacacggt ttagagcttg tttcatcaaa gagattttct ctttttcctt caacttttta
    61261 ccaactaaac ccagattgag attctctttg acggtttggc tttcaattaa gccaaaatct
    61321 tgaaataagt atcctaagta atctctaaag aaaacagaag gcttaatgtc cttaagagaa
    61381 gtgccatcat atatgatttg ccctttgtca tatggctcta atcgtccaat catattcaag
    61441 agtgttgtct taccacagcc acttgtaccg attaaggcat aaattttccc accttcaaaa
    61501 tgaagattcg tatctgaaaa tagctgacgg cttccaaatt ttttagatat attctttagt
    61561 tcaatcatcc tattttcctt tcataattgt catagaaaca cgagattctt tctgcgcttg
    61621 acggtaaagc gtcaaaactg cactagctag aaagaccaat aaagtgagta agccaatcac
    61681 caagtctcga ctgcttaaaa taaagagact agcaccaaat acaaaactgg caaattggct
    61741 aaccatatac tgagcatgtg tttcaaaaaa tcgtaaacct gaaattcgtt taatcaagat
    61801 atctcggcgg aattgctcga aatatagaag attgacagaa taaaagagta acaaggaact
    61861 ggctattcca acaatagctc ctaagattaa agttgctgtt tcagtttgaa cttcattata
    61921 acgagttaga taaacacttc ttccttcttt aagataggat acttgctcat aaattccagc
    61981 tttcttcaag agttctagcc cactctcata tcctttgata aagagttgtt ttccagcatt
    62041 gatagaccaa ctagataagg atataaaact atcacctgta gaagtcggcg tgaatactac
    62101 taaaatcgga tcagtcaaat actgagtgga tacgggattc tcaccgttat tataaacaaa
    62161 ccgcttttct cccattgaaa gataactaac gtgcgctttc atctcataat ccaaaggagc
    62221 acttgcctcc tcaccagatt ttccataata actcaatctt tcttcaaaaa ctttcttaag
    62281 ttctgcttct cgagagcgca aatgttctgg gagcaagagg ataaactcac ctttttggag
    62341 atgggctaac ttctgtttgg tctcagcatc taccacgacc ttttccttgt ccaaataact
    62401 gggactaaca tagagcgtat tagcatctgg actataggta tccagtgtct ctccctgttc
    62461 attttttcct tgtggattgg caaaatggag cagattatcc tttacataaa gagcttgttc
    62521 ttcttcgatt gcttccttgg caaaggcata ccacttgctc tgattttctg tatcttttcc
    62581 tctatcacct aagccaaaag aaatttgata atagtctgct ctatcctgcc atgcttgttt
    62641 tgaaatttca agttctttca atcgttggta agacgtcaaa cctgtcttaa cagcgtatcc
    62701 tactgtaaag acagcaacca actgacacaa tagggttaaa atcatcaggc gtttaagggg
    62761 taatctcccc ttaataacgg gaactaatgc tttgtaactc aaactcatta ggtaaaggag
    62821 cattagtaaa attgaaatcg ccaataaaaa caacagatag aaactaatcc caaaaccata
    62881 ggtggctaac aagataggat aaaacaaacc ttgactaaaa agaacgactc ccccacctag
    62941 gaaggaaagg agggctgata gaaggagcca tttgatatca gtagataaag aatgccccat
    63001 gatggataag agagtctgac cagaaaagag ttttatacct gctgctctca tttccttaat
    63061 ccgagtaata atcaccagag caaagaaaga taagccaaat attgctaaac taattaaaat
    63121 aaggggattt agtaatattc gaaaagcaag aaaatagggc ggtatctttc ggtcagcact
    63181 tgctttataa cccaaatctc ctaatttatc ggcaagcttt tctttcgtca aggagcctga
    63241 caaaaggaga taactattta gcggatcact acgttcacga ctttcttggc tagcttcttg
    63301 gaattctttt ggtaaagttc cctgaccata agttgcataa gtaaagtgag tcgtcccatc
    63361 cttactcggc tctacaattc ttctagctat taaactctgt tctgagtttg caaaattctc
    63421 caattcctgt tcaaatacct cacgcgtcgg ttcctgagta tcttttttga cacgaagtaa
    63481 agaaacggaa tcatagcttg catataaata ttgtggcgca cgtaagacaa taatccaagc
    63541 aaggaagaag ctgagaaaaa aagttgataa taatatgaat agtttcttca tagtagactc
    63601 cttggtagac tccttgtaaa caaaattccc cctgtaattt cttacaaggg gaacgattta
    63661 aatcaatgaa cgattagtca taatcacagt aaaatgctac ttgttctccc catttagtcc
    63721 aaatccatgc ataggaggtt tttccagcag gagcttctcc tttatcagaa tgaccatccc
    63781 atctgctcac gatggatgaa taatgatatt ttttaccatg atagtaattt gaaaaagccc
    63841 aaccacctcc tgaaccttct ccatatgtcc atactcctcc atctggatat tgtacagcag
    63901 ttgatgcagc tcccaataat gtaaaacttg aaataagaac tagagcaagt aatctatgtt
    63961 ttttcgtttt cattttattt tttctttcaa aaaaagcaca ccttgagcaa caatgcaaca
    64021 aaataaaccc tcctctctct tttgttgaaa ccgctttctt atgtgataag aataacattt
    64081 ttattatttg ttgtcaagga aaaaatcgaa tttttagata ttttactata ttacctctat
    64141 gaataatatt atatagtagt tttatttcaa aataatatgc aaccagtact aagcaaatat
    64201 aaaatagatt ccattaaaga attttattca agtttttccc attcatatta tccaaacaaa
    64261 agagatggtg ataactcaaa aataaattgc aatcttgtaa aattcctagc aaaaaagaga
    64321 gccgaaactc tcttttttat cttcttttac tttttttgac tggcatgagt gtgatgtctc
    64381 taacactaaa gtaagctagg atcaacatgg ctattgctag gaatatttct gttggtaatt
    64441 gaaaaatttt cagaaaagat agaaccaata aaatcaagag tgccactaaa atacatacca
    64501 tagcgacgat attgacagtc cctttaatgc tttctggtgt cgcaaataca tagagtagga
    64561 gcagtaaaat tcctaggact aaatagacca tctttctctc tttctaactc ttattcagct
    64621 gattttttct tcttgttagc tttctcacgc tctgctttgt taaggatttg tttacgcaaa
    64681 cggatagact caggcgttac ttccatgtac tcatcgtcgt tcaagaactc aagagactct
    64741 tcaagggtca agatacgagg cgtcttgata acagctgttt ggtccttagt agctgaacga
    64801 acgttggtca tttgttttgc cttcgtgatg ttaactgtca agtcattttc acgagagttt
    64861 tcaccgatga tcattccttc ataaacctca gtacctgggt tgacaaagat cgtaccacgt
    64921 tcttcgatag acatgattga gtaagttgta gccttaccag catcgataga aacaagggca
    64981 ccacggtgac gtccaccaat ttcccctgga atcaatggca agtattggtc gaaggtatgg
    65041 ttcatgatac cgtaaccacg agtcattgac aagaactcag ttgagtatcc aatcaaacca
    65101 cgcgctggaa caaggaagac caaacgagtt tgaccattac cagttgaaat catatccaac
    65161 atttcacctt tacgttcaga aaggctttgg ataacagacc cttggtattc ttctggagtg
    65221 tcgatttgta cacgttcaaa tggttcacat ttaacaccgt cgatttcttt tacgataact
    65281 tctggacgag atacttgaag ttcatagccc tcacgacgca ttgtttcgat aaggattgac
    65341 aagtgcaatt ctccacgtcc tgaaacagtc catttatctg gtgaatcagt tgggtcaaca
    65401 cgaagggaaa cgtctgtttg caattctgcc tgcaagcgtt cttccacctt acgagaagtt
    65461 acccatttac cttctttacc agcaaatggt gagttgttga ccaagaaagt catttgaaga
    65521 gttggctcat cgatgtgtag gattggaaga gcttctactg catctgtcgg agtgatggtt
    65581 tcaccgacaa agatgtcttc catacctgaa acggcaatca agtcacccgc tttggcttct
    65641 tggatttcac gacgttccaa accaaagaaa ccgaagagtt ttgtaacacg gaagttttta
    65701 gttgtaccgt caagtttaga aagggtaact tggtccccaa ccttaactgt accacggaag
    65761 acacgaccga taccgatacg tccaacgaag tcattgtagt ccaaaagtga cacttggaac
    65821 tgcaaaggct catctgagtt atctactgga gctgggatat ggtcgataat cgtgtcaaag
    65881 attggtgcca tagtcgcttc ttggtcagct ggatcatctg acaatgaaga agttccgttg
    65941 atcgctgaag cataaaccac tgggaaatca agctggtcgt catctgcacc aagctcgatg
    66001 aaaagttcca agacttcatc cactacttct gctggacgag ctgatggctt atcgattttg
    66061 ttaacaacca cgattgggac aaggtcttgt tccaaggctt ttttcaatac gaaacgagtt
    66121 tgtggcatgg ttccttcata ggcatctacg accaagacaa caccgtcaac cattttcatg
    66181 atacgctcaa cttctccacc gaagtccgca tgtcctggtg tgtccataat gttgatacga
    66241 gttccgttgt aagcaacggc agtattttta gcaaggatgg taatcccacg ctctttttcg
    66301 atatcgtttg agtccatagc acgctctgcc aattcagtac gtgcatcaag cgtttctgat
    66361 tgtttcaata attcgtcaac cagggttgtt ttaccgtggt caacgtgggc gataatcgca
    66421 atgttacgga tatcttctct taattttgtc atgatttcct ctataatatt caaaatttat
    66481 tttctaactg aacgattata ccataatttc aaataaataa cataactcaa gcaagtgtaa
    66541 atgttttcac tccgcttttc ttttcacgtc aagccttttc aaagcaagcg acttatgata
    66601 agataggcac agtatgcgtt tagataattt attagctcaa gaaaaaatca gccgaaaggc
    66661 catgaaacaa gccttactca aaggggacat tctcgtcgat agttgcccag cccgatccct
    66721 agcccaaaat atcgatacag gactacaaga actccttttt caggatcgaa tcattcaagg
    66781 ctatgaacac acctatctta tgcttcataa acctgctggt gtcgttacag ccaacaaaga
    66841 caaggaactt ccgaccgtca tggacctgct tccatctgat atccagtctg acaagctcta
    66901 tgccgtcggc cgactggacc gagatacaac aggactcctt ctcttgaccg ataacggtcc
    66961 cttgggcttt cagctcctcc atccccaata tcatgtcgat aagacttatc aagttgaggt
    67021 taatggactt ctaacacctg accatatcca agcctttcaa aagggaattg tctttttaga
    67081 tggtactgtc tgtaaacccg caaaactaga gattctatct gcaagtccct ccctcagtca
    67141 agcctctatc accatttcag aaggaaaatt tcatcaaatc aagaaaatgt tcctctcggt
    67201 tggtgttaag gtaactagcc tcaagagaat ccaatttggg gacttcacat tgaacccaga
    67261 tttagcagaa ggtaactacc gccctttgaa ccaaaaagag ttacaaatca ttaaaaacta
    67321 tttagagatg agtcgataaa ataaagaaag ctttaaaact aaagcttttt tcttttattt
    67381 accgaaaaat taaggcgatt gctacaatcc agttaactac agaaatcaca attcctaaga
    67441 tattaagaat cttttctatt ttatagtcta attgtgactc tttttggtat gaaatagcca
    67501 agaccaatcc tatgataccc aaaatcaggc ctacaattgg aaataacaaa ccaagaataa
    67561 tcgacaagat acccacaaaa agtggatttt tcttcttttc tttcatgttc taagaactct
    67621 ttaaatttta tacaaattaa ttatactata aaacaatagc ttcatcctat cattcgacta
    67681 atttggaaat aaggttagct agtcttcact ttccctttcc aagaatccaa gccataagaa
    67741 aggatataaa tctcagaaaa accttgtttt ttcaagtaaa gagctgcatt tgtaactcgt
    67801 tgcgcacgtt ggttttcgta gagaaggaca ggtttatctt tacgaagggc tgcaagacta
    67861 gttttcaact gacttgaagg aatattgcgt gcaccaagga tatgttttct gtggaattct
    67921 gctgggtcgc gcaaatcaat caattgaccc gtacgaatca aggcttcaaa ctccttattg
    67981 tccacaattt tagccgcacg gcgaatacga agatagttaa agcccatcca cgccaacatt
    68041 gctagtataa gtgcccacaa aatccaagta accattagtt cttttctcca tttttctcaa
    68101 tataatccaa ttctaccttg tgctctctgc gaagaactgc ttctgcctct agatagtcta
    68161 atttatccat caaccctgca tcgtaaatcc gagatagttc caacttcatc agttcaatat
    68221 catataagcg ttttcccatg taaacaataa taccaaatcg tttgaggaat tgctgcacat
    68281 catagaatgt tttcataaga ctcattctag caaaattttg tgtttttttc aagaagagac
    68341 tcacacaatg ctccttattt tcctatcttc tttagcgatt ctaaggcaag tatggtacaa
    68401 taaaaacatg agaattcaac aattacatta tattatcaaa atcgtcgaaa ctggctccat
    68461 gaatgaggca gccaagcaac tctttatcac tcagccaagt ctctccaatg cagtgcgaga
    68521 tttggaaaat gaaatgggca ttgagatctt tatccgcaat cccaagggaa tcaccttgac
    68581 ccgtgatggg atggagtttc tctcctatgc ccgtcaggtt gtcgagcaga cccagcttct
    68641 ggaggaacgc tataaaaatc ctgtcgccca ccgcgaactc tttagcgttt cgtctcaaca
    68701 ctatgccttt gtggtcaatg cctttgtctc tttgctcaag aaaagcgata tggagaaata
    68761 cgaactcttc cttcgtgaaa ctcggacttg ggagattatt gacgacgtca agaatttccg
    68821 tagtgaggtc ggtgtcctat ttttgaacag ctacaaccgt gatgttttaa ccaagatgct
    68881 ggatgacaat cacctgctat cccaccatct cttcacagcg caaccgcata tctttgtcag
    68941 caagaccaac cctctggcaa agaaagacaa ggtgaaactg tctgatttgg agaatttccc
    69001 ttacctcagc tatgaccaag ggacgcacaa ctccttctac ttttcagaag agattctttc
    69061 tcaagaacac cacaagaaat ccattgtggt cagtgaccgt gccaccctct ttaatctctt
    69121 gattggtttg gatggttata ccattgcgac agggattttg aacagcaacc taaacggaga
    69181 caatatcgtt tctatcccac tggatattga tgacccgatc gagctggtct atatccagca
    69241 tgagaaaacc agcctatcta agatgggcga acgctttatc gactatctac tagaagaagt
    69301 tcagtttgat agttgagaaa tgataagaac caatatgtag gctagcaaca acctgcacat
    69361 tggttctttt tacttataat taaaagtttc ccctgccaac ttatcagcta gcttgggaaa
    69421 gagagtataa aacttatggg ctaggttcaa caaaatcggg agattgagtt ctcgtttatt
    69481 tttgcctata atcttgacaa tctttttagc cactgcatct gcctctaaga ggaagcggtc
    69541 aaccgattta agataagttc catctgggtc agcttggtca aaaaatcctg ttcggattgg
    69601 acctggattg actgttgtca catagactcc atagggcata agttcgagtc gcagagcatt
    69661 tgaaaaacca atagccgcaa acttggtcgc tgagtaaaga ctagacttgc cagtagctat
    69721 tagacctgcc atgctgacga tgttgatgat atgccctttg ctgctttcct tcatacgagc
    69781 cgcaaggtga cgagacagat tcatcagggc aaaggtattg acctcaaaca tctggtgaat
    69841 atctttatca gcaatctggt caaatccctc aaaaatcccg taaccagcgt tgttaatcaa
    69901 gacatcaatc ttgccatagc ggagataaag atcagttacc agagcttcta gggctgaatc
    69961 gtcggtaata tcaatttcaa tcaattctgc atgggaataa tttccgtaga gttgggctaa
    70021 tttttcctta tttctaccaa gcaagatgag ttggtcattg ggcaggagtt tgaccatttc
    70081 ttgagctaga ccaccgctag ctccggtaat gagaatagta ggcatactta tcctttctgt
    70141 gactgctaga tttccacttc ttccaagtct ttgaccacat ggacattttc aaaaattgtg
    70201 gcagcgtctt tcttgagttt gctaatatct tttgagagga aacgggcact gatatggttg
    70261 agtaggaggc gtttggcacc tgcttctacc gctacttgtg cagcttgcat attagttgag
    70321 tgaccatggt tacgagcaat tttttcatca cccttgccat aagtggactc atgaactagg
    70381 acatctgcat tgacagccag acgcacactg gcatccgttt ttcgagtatc tcctaaaata
    70441 gtgataatct tacctggacg tggcgctgag atatagtctg ctgccttgat ttcagttccg
    70501 tcttccaaaa caagatcctg gccgtttttg attttaccaa aaagcgggcc gaacggaaca
    70561 ccagcagcct tgagtttttc agcatccagc gtcccttcta gatccttttg catgacacga
    70621 tagccagcac agaaaatagt gtggtccagc tcctctgcat acacagtgaa tttatcggtt
    70681 tcaagaattt tacccagaga atcttggtca aactcatgga aatgaatgcg gtagggcaga
    70741 cgagaacctg acacacgaag gctggttaag acaaatgact tgattccttg aggtccgtag
    70801 atttccaaat ctgtctgctc ttcattggcc tgaaaggcac ggctagaaag gaaacctggc
    70861 aaaccaaaaa tgtggtctcc atgcagatgg gtaataaaga ttttgctgac cttacgtggt
    70921 cgaattgtgg tttccagaat gcgattttgc gtaccttctc cacagtcaaa gagccaaact
    70981 tcgttaatct cgtccaaaag tttcagggcg agacttgaaa cgttgcgggc tttagagggc
    71041 tgaccagccc ccgttcctaa aaattgaata tccattcgat actttctaat taatcaatat
    71101 ataacatggc tgtgcggttt tccgatcgga aatagcgttt gccagaaaaa gcagcagctt
    71161 cttgcaataa atcctcttgg ctgtagcctt tgagacgttt tcgaccatca gccaatcttt
    71221 ccaaatcagt caaagctgtg agactttcta ggctgacaac ttcctcgtcc tcgacaggct
    71281 tcatgtaaat cttaccagac tcttcaaaga ctaattgatg ggggaaaatt tgcgcaattt
    71341 caaagagcaa gtcatccgag attttctcct cattttcaga gaaaatccga ccaaagccgt
    71401 cactctcata acaaaaacca aaggatttac cagacagatt aagccgaata aaagacttat
    71461 tttctagggt gaaacttggc tcagtattgt aaagattcag ttcctgactg agttctgcaa
    71521 aataatccgt cgcagcctga ggactttttt tctgatagag ttctgcaaag taggcattaa
    71581 caacacttgg cggaggtgta ataagtgtta actgctcctg ctctgtctta ccagctagaa
    71641 gctgatccag atagaccttg tccagacttg tataacctcc atactttaga gccaaagttt
    71701 taatatcagt cataaaattc ttctaacctc catttatttt tctcggaaat gtagcctgta
    71761 atcacttcgc cgtcttcctg ataatcacgt tcttccagaa ttgcaacact ctctaaatca
    71821 tgaatcttgt aggactttga aaaaggcact cgcagggtaa atgcttcaaa aatttcctta
    71881 atcttatcta gcaataatgc ttgcaagttt tcacgactgt cctcagactt ggcagaaatg
    71941 agggtatatg gcgtttgggt aggcgtgaaa tcctccacca aatccgcttt attataaagc
    72001 gtcaagtgag gaatatcttc catgtccagg tctttcatga tggagagaac cgttttttca
    72061 tgttcctcgt ggtaaggatt gctagcatcg ataacatgaa ccagaaggtc cacatgcttg
    72121 ctttcttcca aggttgactt gaaactggac accaactctg tcggcaaatc ttggataaag
    72181 ccaacggtat ctgtcaaagt tacttggagg ttgcctccca gatgaatact cttggttgtc
    72241 gcatccagag tcgcaaagag ctcatctgct tcatactggg tcttactggt caagatgttc
    72301 atgatagttg atttcccagc attggtataa ccaatcaaac caatcttaaa agtgctagac
    72361 tccaaacgtt tttctctgac agtcgcacga tttttctcaa ccaccttgag ctggcgctcg
    72421 atatccgtga tttgattgcg aacgctacga cggttcagct ccagttggct ttcaccagga
    72481 ccacgggaac caattccccc tgcctgacgg ctgagcataa tcccctgacc aaccaagcga
    72541 ggcaagaggt atttgagttg ggctaggtgg acttggagct tcccttcatg gcttcgagcc
    72601 cgcatggcaa agatatccaa aatcaactgc atacggtcaa tgaccttaac accgagaact
    72661 tcctctagat tgacattctg ccttggggtc agacggttgt tgacgatgac agtagtgatt
    72721 tcttctgcat ccaccataag cgcaatctct tccaacttac cagagccgac gaaggtcttg
    72781 gaatcatatt tttcacgttt ttgtctgtag ctatctacaa cgactgcccc tgccgttttc
    72841 gctaaactag ccaattcttc catggagagg tcaaaactgt ccataccctg caattccaca
    72901 ccaatcagca ggactcgctc ctcttttttc tccgtttcaa tcatctaaaa actcctctat
    72961 ctggcttaaa atgcggtctt gtacaccaga ttctccaatc tgataaaagg tgacctgcat
    73021 gcgattacgg aaccaggtca gctgacgctt ggcaaaacga cgggtcgcct gtttgagact
    73081 ctcactagct tcctccaagg tctgctctcc acggaaataa ggaaagagtt ccttatagcc
    73141 aattccttta gcagcctgta cattagggga atggtcaaac agccacttgg cttcatccaa
    73201 aagcccagcc tcaaacatca aatccactcg gtggttgata cgctcataaa gttgactacg
    73261 ttcatcatcc aagcagataa tcagcggttc atacaaggtc tcttgatttt ccaaatcctg
    73321 accaaaatgg gcaatttcta aggcacgcat agcacgacga cgattaaact ggggaatctc
    73381 aaggcctgct tgatccacca aatgggctaa ttcctcatct gaatatggct ccaaactagc
    73441 tcgataagct aaaatctcct catgaggagt ctctccacct aggtggtaac cttctagcaa
    73501 gctctggata taaagtccag tcccaccggc gataatggct agcttgccac ggttgtgaat
    73561 accctcaata gtcatcttag tttctgaaac aaaatcaaaa gccgagtaag actcggttat
    73621 ctctctaaca tcgattaaat gatgaggaac agctgcctgc tcttctggac tagccttggc
    73681 cgtcccaata tcaagtcctc gatagacttg ctggctatct ccactaacca cttcgccatt
    73741 aaaacgcttt gcaacttcaa tagctagagc cgtctttcca acagcagtcg gtccaacaat
    73801 cacaattatt tttgttttca tcttttttcc ttgaaaaatt cccatttttt cgttactatt
    73861 attataacac aaaaaggtca gtcagaaaaa tgtgacctct tgaggaggct ggctgattga
    73921 gaatataaag gaggaagact catggctaaa ggattcgcta aaggtcttgt aacaggtgtc
    73981 gcaggaactg tcgctgccgt tgcaggtgca gtatacgcat ttaaaaagaa agtaatcgaa
    74041 ccagaagagc aaaaagcagc tttcatcgaa gaaaaccgta aaaaagcagc tcgtcgccgc
    74101 gtatcacgtt aagaaacaaa agaagttggg attattctca acttcttttt tctattcttt
    74161 taaatagcta ggtcaaactt caactgtggc ttaacagggt cataatccac caactcaaaa
    74221 tcttctgctt tgatatcaaa gaaattagtc ccatcaggaa catttaaaac caagcgtggt
    74281 tggcagtttg acggctcccg acggagcaat tcctgagctt gttcaaattg attatcatag
    74341 atatggaggt tgttgatgaa gtagaagaac ttcccaacct tccagccaaa atgtttggca
    74401 atcatcatct gcaaagccac atactgcata gcgttgatgt ggtgggctac tagcatgtca
    74461 ttggagcgct ggatcaaggt cgcatccaga tagatttccc catcaacacg ccggacatca
    74521 aacatggtct gaaaggcgca cgggagcagc ccatctgttt cttcgaaagc ttggtaatcc
    74581 cagagcgaaa taatattgcg gcggttccaa ggattggttt ccaactgttt gagaagctta
    74641 ttgataatgt cgtgtttctt aacaacggca ccatagcgct caccaatggt tcccgtgtct
    74701 ccaacttccc agtcattcca gtagtgaaca ttgtacttgt cattaagcac ttctaagcta
    74761 tttgactggt cttggtaaat ccagagaact tctttgatgg cggatttgat tgcaatggga
    74821 cgcaaggttg tgataggaaa ttctccttta gataagtcgt actcggaaaa ggcaccagtt
    74881 acatacttgg aattagcaac agtcccatcc ttgtacttag gacgagcctg ctctgagaaa
    74941 acaccttcct ttagaatgcg ttcaatattc tctttaaaaa tcgtatctgc ttttgtcatt
    75001 tcgtttcacc tcattcattg tcctaactag tatagcataa aaaataaaag aggaacatta
    75061 ctaactctag gttagcattt tcctctctca ttatcttatt gcaatacaag tgatgctgct
    75121 ccgataactc cagcgtcatt tcctagagtt gcaagagcta atttagtaga tgtgcgtact
    75181 tgtgggaaac tattttcatc gtaaactttt tgaacacctt gtagaaggaa ttctcccgca
    75241 gctgacacac caccaccgat gacgattgtt gatgggttta ggattgaacc aatgttagca
    75301 caagcgattc ccaagtaacg tgagaagtta cggtaaacaa tcaaagcaag gtcgtctcct
    75361 tcttttgcga gatcaaagac agtcttagca gttacttctt ctccgttatc aatcaagcgt
    75421 ttcaaggctg catcgccttc gtattcatcg gcatagcgac gagtcaagtt gacaatccct
    75481 gttgctgaag caactgtctc aaggcagcct ttcttaccgc aagtacatgc gattggctgg
    75541 tcaaagtcaa cagtgatgtg accaagctca cctgctgcac cagcaacacc gtgaagcaat
    75601 ttgccttctg cgacgatacc gccaccaaca ccagtaccga gtgtcataaa gacaacgtct
    75661 ggttggttat ctccagcacc catccagcgc tcaccaagag ctgctacgtt ggcatcatta
    75721 tcgatgaaaa atggaatgcc caaagctttt tcaatctttt gtttgattgg ttgaagggtt
    75781 ttccagttca agttgtaggc accgataaca gtcccttttt cacggtcaac cacacctggt
    75841 gatcccattc caatgccttg gaagtccgct gctgccaatc caagcaagtc caaacgatgt
    75901 tgaatagact caatcatatc atcaacgata tgacttccct catccaaaat gtttgtcttg
    75961 attgaccatt ttccttggat ttctcctgct gttgttaaga ttgcaaattt gatagaagtt
    76021 ccaccaaggt caatcccaat aatcttttga ctcatcatat tctccttttt cattgtgtag
    76081 taattgaaaa tgcttacagt actagtatat caaaatccat tcacttatgc aaaggtttgc
    76141 gtaaatgaat tataaggaat tttttcgcct accagtatct gttaatcatc taaatgatca
    76201 atggcatatt gagctgcatc atttgaaaat ttatcaaaat cagaagttaa ttgtctatac
    76261 atacgttttt ttgacatgtg gaataacgaa ttataacttt ttgcctttcc taaagcagca
    76321 gaatattcac tattgctatc attactagaa gaagctgtac ttgcttgacc ttccttccaa
    76381 actccgtcat cgccaacata ataacgtcca ccatcaaccc attcattgac agccatttta
    76441 ccatccgatt ttagatagta atttccttgc catgtactgt aagcataaga accatctgat
    76501 gtcaaataat accaagcttg ataagaagag tcataaatcc attcaccttt agccatttta
    76561 ccatctgatt tcaaatagta attgccttgc catgtactat aagcatacga tccatctgat
    76621 ttcaagtaat accaagcctg ataagaagag tcataagccc attcgctctg ggccatttta
    76681 ccatctgatt tcaaatagta attgccttgc catgtactgt aagcatacga tccatctgat
    76741 ttcaagtaat accaggcttg ataagaagaa tcataaaccc attcgctctg ggccattttt
    76801 ccgtctgctt tcaggtaata gcttccctgc caagcatttt tcactggatt tccatttcca
    76861 tcaaagtagt accaagcgcc gtcctgctta acccaaccac ttgttgttgc tgaacttgtg
    76921 ttgatttgag tagccgttga ctgttttgct ttaaaagcac ccttaggagc atttttcaat
    76981 tcgcaagcca caccatcatg atcacggtct aacttggcag aataaccagg ttctccctcg
    77041 tgaatatccg aatagccatt cccccaagct tccttacagc tcgaaaaatg gatgttttct
    77101 tccgccaaaa ctggttgtga aaacaaggct aaaactggta atgtagccag actcattttt
    77161 aaaaatagac gtttgttcat ttgtttctcc tataacgata atatcgattt tagtattatt
    77221 ttacaaaact tatttcagca attcaaggaa acttctgatc ttttctacaa actcctttgg
    77281 ttttgcctta ttcaagacat gagggccatc aggaatgatc tgaaactgcg aatctgtcaa
    77341 cagtctatgg agagttttca tagaactaag attcggtcta tctttgctgc cacaaattag
    77401 taaggttgga taggggcaaa tccctgctat atccgttaaa tcaagtgtct tcaattcctc
    77461 agaaactccg atcataagag tcttatctgc tccctgtttt tcaaataccc ttttgggaag
    77521 tagtttaaaa atcagcaact gaagataaaa tagaatattc cctgctaatt taagcgggca
    77581 tcctgataga accaaagctc gaagatttgg taaatcgtaa ctggaaagtt ctagtgccag
    77641 ggcagcacct aaggacaatc caatcaaaac aaaaggttct gtctcttgag ctaggtgttg
    77701 ataaactcgc tccttggctt tttgatagct gctaactcca gaaggaaata actcaatagc
    77761 ctcagaagga taatctgtca gtagatttcg aacttctttc caagactctg ctgactgccc
    77821 taacccatgt aaaaatatca gtttcatcta gttctcctgt aagattaact catacaagcc
    77881 tctcactgca ttacagccgt aaatagcttc tgcttgggct aaatctgcca aggtcaagac
    77941 tttctcttct acctgtcctc tttccagcaa atgctgacgg taaattcctg gcaagattcc
    78001 aagttcgata ggcggtgtgt agagtctccc agaaattttc agaaccaaat ttccgattga
    78061 ggtttccaat agctctccag ctgcattatg gtaaataatt tcctgcttcc ttaggcccaa
    78121 gtgaggtcgg tggcttgttt tgaagtaggt aaatgcttgt tgcaaattgg cttcctgaag
    78181 acagagttgg gcatagcaga aggttcgact gagaggtgtt aatacttgac gattgacttc
    78241 tatctctcca gacttgctaa ggctaattcg caagcggtaa tcttgattaa catcacaatc
    78301 ctgacactct tcctttatct tttgtttcaa gtcttctgca tcaaaaggag aagcaaaata
    78361 gcgactagct tttctcagcc tttccagatg ttgtgcttca aacagcaggt tcttctggct
    78421 gattttccca gtagtaatta gctgaaaacg agcttgttta cgatagagaa cagctgcctt
    78481 ttgatgaacc tcttggtatt cagattccca agtgctatcc catgtaatgc ctccgccaac
    78541 tccatagatt gcttgacctt tgtgaagttg aatggtacga atggccacat taaaaatccg
    78601 tcgtccattt ggaagcaaga gaccaatcgt tccacagtag actccgcgtg gttgaggctc
    78661 taaatttttg ataatctcca tagtcgcaat tttcggagct cctgtgatgg atccacaagg
    78721 aaagagagag cgaaaaatgg taatcaagtc aacatctgct cgcaaccgac tcttgatggt
    78781 cgaggtcatc tgccaaacag tagaatactg ctctacctga cacagatgct ccacgtgctc
    78841 actgcccact tcagaaatac ggttcatatc attgcgcaag agatccacaa tcatcatgtt
    78901 ttcagagcga tttttggggt cctgttctaa ccaactggcc tgttcaagat cttcttggtc
    78961 agttacccca cgctgggtcg ttcccttcat tggtctcgta gccaattcac ggccattttg
    79021 ctcaaaaaag agctctggac tcatggaaat cactgccatc tcgtcatgtt ccacataggc
    79081 attgtagccc gcctcctgct ctatcaccat acgattgtag atggcaaaag gattggcatt
    79141 taacttttgc ttaagttgga cggtgtagtt gacctgatag gtatctccct gccgtaaatg
    79201 atgatgaatt tgggcaatcg ccttctcata gtctgctgca gacgtcactt cctgccaatc
    79261 agaaggcaaa tcaacctcat cataagtcag aggaataggg gatgtttcta cactatcatg
    79321 aactgtaaaa tatagcaggt actctcccag tagaggagcc ttatgaactg caaacttctc
    79381 ctcaaaagca ggagcagcct cgtagctgac atagcccacc acataatagc cttgcttttg
    79441 gtagctttcc acttgtgcca gcaagtctgc cacttctgct acatttctcg tttttatctc
    79501 tttgataggc tgggtaaagg tgtatctctc ccccaaagcc ctaaaatcaa tcactgtttt
    79561 tctatgcata ccttaagtat agcataaaaa ggcagatcaa gaaaaactta atctaccttt
    79621 ttatgatttt atggctctat aatatttgta gtgggtaacc cccctatgga tattacggag
    79681 cctattttgt gtagaaaaaa aatcccataa gatctataat gaaaagcgac aaaacaactc
    79741 attagaaaga atcatatgga acaattacat tttatcacaa aactccttga cattaaagac
    79801 cctaatatcc aatttatgga tatcatcaat atggatacac acaaggaaat catcgctaaa
    79861 ctggattatg atgccccatc ttgtcctaat tgcggaagcc aaatgaagaa atatgacttt
    79921 caaaaaccat ctaaaatccc ttaccttgaa acgactggga tgcctactag aattctcctt
    79981 agaaaacgcc gattcaagtg ctatcagtgc tcgaaaatga tggtggctga gacttctatc
    80041 gtcaagaaga atcaccaaat ccctcgtatc atcaaccaaa agatcgctca aaagttgatt
    80101 gaaaaggctt ctatgaccga tattgctcat cagctgtcta tttcaacttc aactgttatt
    80161 cgcaagctca atgacttccg gtttaagcat gatttttctt acctccctga gattatgtcc
    80221 tgggacgagt actcctttac caagggaaag atgagcttta ttgcgcaaga ttttaaaaaa
    80281 ctcaacatca tcgctgttct tgagggcaga acacaagcca tcattcgaaa tcactttctg
    80341 cgctacgata gagctattcg ttgtcaggta aaaatcatta ctatggatat gtttagccct
    80401 tattatgcct tggctaaaca gatttttccg tgtgctaaaa tcgttctgga tcgctttcac
    80461 attgttcaac acttaagtcg tgctatgagt cgtgtacgtg ttcaaatcat gaagcagttt
    80521 gagcgaaaat cccatgaata caaggctatc aagcgctact ggaaactcat tcaacaggat
    80581 agccgtaaac tcagtgataa gcgattttat cgccctactt ttcgtatgca cttaaccaat
    80641 aaagagattc ttgataagct tttgacctat tcagaagact tgaaacatca c
//
LOCUS       DAVDZK010000004        75286 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVDZK010000004 DAVDZK010000000
VERSION     DAVDZK010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75286
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.004"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(279..3845)
                     /locus_tag="VUX16_000323"
     CDS             complement(279..3845)
                     /locus_tag="VUX16_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HET8123370.1"
                     /translation="MFLYLKGLGKYRKSKAYGLVGCLALVSMIGLAAPDLPVIGGGVV
                     AADVIQGGNDIKDVNVHSKSAEGVAMTYTTYDSGTSGKQTASGSGVFVAPNVMVTVAH
                     NYYDKNQEDKSAVLRGGASARSYVVMNSETEKHNKVPTSGVSETLEKDSIHLYDEKNF
                     GKDYSNDLAVVVTKKTVEAMTGGEDSPRELSHKEVSTGDKISMVGYPNDFSTPNLSAE
                     NKARLKDGKAYSVTTTVSSVNKESGTVTYHSSALGGFSGAPLFNDKGEVVGIHQHGTN
                     TPNAQESERIGGGTLFTEKHRAWIRSMIDKYGIKGWYIDGANRYYYDENHRALKDVES
                     EIDGALYRFDEKGRATLLEGEEKGRVLLRVEDTKGTPLISDKVVQEGSVGSGLNFHLR
                     QNPNFKQLIATSPTAKVVSYNGVPINKLASDTSWSDEYVSKLALGDTIIRAVVDSVTP
                     PSTSSSDFARTEVGKVDLSGKSNLPVPSKEVLQAPNGSENFYATTHIQTPDGSGSGTL
                     IAPNLVLTVAHNFLTVKGSEVVTKSGRTNTVYKATLPSGQPVNFSDDDIVYWNKKDSV
                     FGFKNDLALVRLKEKLTAVSPVEVVSESTSITKGDKVSVYGFPDGRLSPVLDSEVVAT
                     TDFGSGIEGISYGGTKPGASGGGLYNDKGSLIGVHQNGVVGSRSGGLVLSKEQLDWVR
                     SYIEGKPKAPVYVTDNILVDEKDKDKLPSTSKEEKPTTPKVESDKDKPNTPLKPQEKP
                     KTEVITSYEGDSTLEVGKERTEETEGEKEGVSLIYRTVYKGTKSKTEMSPIAFDTVYQ
                     GDETKELGFRSVLEGKEGLVTRTTSYQVDKYTGAVSSKISEEKIAPQSQVITLGIKKN
                     SSTKEVPITERFEDSAELEKGKTEVISEGSVGKEVTTVTYKVLPDGKVIENSRTVDVT
                     PMRERVVRKGVKEVVSPDKVESLVPKDAPIREEQPALSEGFSESDALVSGEKIQGDLG
                     ILIVSSEELVPERVEVPDFVTKVTGGEKLTVEGHRNESKIKTPSKQERSSRPETTAQF
                     TTNGTGSSSLTAVFGGKTDKILLSTVEHSVIKHNQQRGWHKINNQWYFRNSDGKERTG
                     WMKENDAWYYFDTNGTMQTGWLEDTDGNWYYLNDNGRMEIGWFQDSSGAWYYLGSSGR
                     MESNTWIYYKGKWYYIDALGKLLFNSVTPDGYRVNEYGEWIN"
     gene            complement(4517..7400)
                     /locus_tag="VUX16_000324"
                     /pseudo
     CDS             complement(4517..7400)
                     /locus_tag="VUX16_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285043.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
     gene            complement(7516..7743)
                     /locus_tag="VUX16_000325"
     CDS             complement(7516..7743)
                     /locus_tag="VUX16_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123371.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            complement(8596..9552)
                     /locus_tag="VUX16_000326"
     CDS             complement(8596..9552)
                     /locus_tag="VUX16_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET8123372.1"
                     /translation="MKNPALLEEMKIYLGRDEVPEDVDAFWDEEVKKVSTLPAYQLEE
                     INFHISQVKCYELTFEGSKQGKVYARVVLPKSEEKVPLIFHFHGYMGRGWDWADMLAF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIIASLPQVDEKRLSSYGASQGGALALVAAALNPRIQKPVAIYPFLSDFRRVLEIGN
                     TSEAYDELFRYFKFYDPFHETEEEIMAILAHRIKGEVKMITGLDDDVCYPITQFAIYN
                     RLTCDKAYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(9873..11888)
                     /gene="recG"
                     /locus_tag="VUX16_000327"
     CDS             complement(9873..11888)
                     /gene="recG"
                     /locus_tag="VUX16_000327"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET8123373.1"
                     /translation="MNLHQPLHVLPGVGLKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKASLPFALTQAQEKSLQEILIDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTAHFAGKAEVALLHGKMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVVSYISSIEGWQEDPEWRMIAFHLEKKEHLD"
     gene            complement(11907..13010)
                     /locus_tag="VUX16_000328"
     CDS             complement(11907..13010)
                     /locus_tag="VUX16_000328"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET8123374.1"
                     /translation="MKASPHRPTKVLIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAY
                     GHGAVAVAKEIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(13000..13368)
                     /locus_tag="VUX16_000329"
     CDS             complement(13000..13368)
                     /locus_tag="VUX16_000329"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET8123375.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(13407..14438)
                     /locus_tag="VUX16_000330"
     CDS             complement(13407..14438)
                     /locus_tag="VUX16_000330"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET8123376.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(14440..15471)
                     /locus_tag="VUX16_000331"
     CDS             complement(14440..15471)
                     /locus_tag="VUX16_000331"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET8123377.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYARRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(15552..18065)
                     /gene="secA"
                     /locus_tag="VUX16_000332"
     CDS             complement(15552..18065)
                     /gene="secA"
                     /locus_tag="VUX16_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET8123378.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(18211..18498)
                     /locus_tag="VUX16_000333"
     CDS             complement(18211..18498)
                     /locus_tag="VUX16_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123379.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLTFFFFPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(18509..19159)
                     /locus_tag="VUX16_000334"
     CDS             complement(18509..19159)
                     /locus_tag="VUX16_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET8123380.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            complement(19163..19804)
                     /locus_tag="VUX16_000335"
     CDS             complement(19163..19804)
                     /locus_tag="VUX16_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123381.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FLDYTRKRLVVISKFFTQDLFVWFLGLLPIGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            complement(19797..20588)
                     /locus_tag="VUX16_000336"
     CDS             complement(19797..20588)
                     /locus_tag="VUX16_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123382.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLTLVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPITIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFFKIVDYLGNVTRSAIAYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(20773..21108)
                     /locus_tag="VUX16_000337"
                     /pseudo
     CDS             complement(20773..21108)
                     /locus_tag="VUX16_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(21248..21583)
                     /locus_tag="VUX16_000338"
     CDS             complement(21248..21583)
                     /locus_tag="VUX16_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123383.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(21674..22984)
                     /gene="der"
                     /locus_tag="VUX16_000339"
     CDS             complement(21674..22984)
                     /gene="der"
                     /locus_tag="VUX16_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET8123384.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIHEQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(22998..23711)
                     /locus_tag="VUX16_000340"
     CDS             complement(22998..23711)
                     /locus_tag="VUX16_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET8123385.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(23708..24604)
                     /gene="dnaI"
                     /locus_tag="VUX16_000341"
     CDS             complement(23708..24604)
                     /gene="dnaI"
                     /locus_tag="VUX16_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET8123386.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKQASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEELELHFAKGKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(24605..25774)
                     /locus_tag="VUX16_000342"
     CDS             complement(24605..25774)
                     /locus_tag="VUX16_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET8123387.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLRHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPISSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKNQAQKSSTPSPAKSNVPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(25775..26248)
                     /gene="nrdR"
                     /locus_tag="VUX16_000343"
     CDS             complement(25775..26248)
                     /gene="nrdR"
                     /locus_tag="VUX16_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET8123388.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            26388..26753
                     /locus_tag="VUX16_000344"
     CDS             26388..26753
                     /locus_tag="VUX16_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET8123389.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     SVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            26758..27453
                     /locus_tag="VUX16_000345"
     CDS             26758..27453
                     /locus_tag="VUX16_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123390.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            27470..28237
                     /locus_tag="VUX16_000346"
     CDS             27470..28237
                     /locus_tag="VUX16_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123391.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(28590..29789)
                     /locus_tag="VUX16_000347"
     CDS             complement(28590..29789)
                     /locus_tag="VUX16_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8123392.1"
                     /translation="MRNMWVVIKETYLRHVKSWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETLLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMASRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(29786..30679)
                     /locus_tag="VUX16_000348"
     CDS             complement(29786..30679)
                     /locus_tag="VUX16_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123393.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            30796..30876
                     /locus_tag="VUX16_000349"
                     /pseudo
     CDS             30796..30876
                     /locus_tag="VUX16_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            31386..31574
                     /locus_tag="VUX16_000350"
                     /pseudo
     CDS             31386..31574
                     /locus_tag="VUX16_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            31989..32606
                     /locus_tag="VUX16_000351"
     CDS             31989..32606
                     /locus_tag="VUX16_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET8123394.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQMI"
     gene            complement(32649..33536)
                     /locus_tag="VUX16_000352"
     CDS             complement(32649..33536)
                     /locus_tag="VUX16_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET8123395.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLAYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(33685..35622)
                     /locus_tag="VUX16_000353"
     CDS             complement(33685..35622)
                     /locus_tag="VUX16_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HET8123396.1"
                     /translation="MDYSKVAAEVIEAVGKDNLVAAAHCATRLRLVLKDEAKVNQAAL
                     DNNADVKGTFSTNGQYQIIIGPGDVNFVYAEIIKKTGLKEVSTDDLKEIANKDKKFNP
                     LMDLIKLLSDIFVPIIPALVAGGLLMALRNFLTSPDLFGPQSIEDMYPAIKGFSAMIQ
                     LMSAAPFMFLPVLVGISAAKRFGANQFLGAAIGMIMTTPDLGGKEAFWDILGFHVTQT
                     NYAYQVIPVLVAVWLLANLEKFFHKKLPSAVDFTFTPLLSVMITGFLTFTVIGPVMLV
                     VSDAITNAIVWLYNTTGAFGMGLFGGTYSLIVMTGLHQSFPAIETQLLSAYNNNGTGF
                     GDYIFVVASMANVAQGAATLAVYFLTKNAKTKGLSSSAAVSAFLGITEPALFGVNLKY
                     KFPFFCALAGSAIGAFVAGLTHVIAVSLGAAGFIGFLSIKAGSIPMYIIAEIMSFVAA
                     FAFTYFYGKTKAASVFADEAATATAETVTEPTVEAPVVEETDTLQNETLVTPIVGDVV
                     ALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIVFPTGHAFGLKTRNGAEVLI
                     HVGIDTVSMNGDGFEAKVAQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYA
                     SVAPVATGSVAKGDAVIEVKI"
     gene            complement(35617..35743)
                     /locus_tag="VUX16_000354"
                     /pseudo
     CDS             complement(35617..35743)
                     /locus_tag="VUX16_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915902.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator T protein"
     gene            35998..37452
                     /locus_tag="VUX16_000355"
     CDS             35998..37452
                     /locus_tag="VUX16_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET8123397.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDKNWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFIEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNCSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSHAGEQYAQEFGITRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            37433..38398
                     /locus_tag="VUX16_000356"
     CDS             37433..38398
                     /locus_tag="VUX16_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET8123398.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(38434..39708)
                     /locus_tag="VUX16_000357"
     CDS             complement(38434..39708)
                     /locus_tag="VUX16_000357"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET8123399.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEQDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKHVGGFT
                     AQVHQRQMIGQVSLYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSSQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(39708..40880)
                     /locus_tag="VUX16_000358"
     CDS             complement(39708..40880)
                     /locus_tag="VUX16_000358"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET8123400.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKNLPQEKKDLLQNHFDHSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTDLSVADYEKVFFEEVDLDETNSAQFAGYENQYFALVEILDHQRRYSKVEK"
     gene            complement(41011..41259)
                     /locus_tag="VUX16_000359"
     CDS             complement(41011..41259)
                     /locus_tag="VUX16_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123401.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QEFVDEMGRTYSGNLILQELITVNEAYKATYIGELYIN"
     gene            complement(41327..41951)
                     /locus_tag="VUX16_000360"
                     /pseudo
     CDS             complement(41327..41951)
                     /locus_tag="VUX16_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(42013..42462)
                     /locus_tag="VUX16_000361"
     CDS             complement(42013..42462)
                     /locus_tag="VUX16_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET8123402.1"
                     /translation="MTLTTFLLQAVASLLAIITFLIVLNVQRSMLLPGGILGMAVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGIASGTVILRLYHYIKTHRVS"
     gene            complement(42464..43222)
                     /locus_tag="VUX16_000362"
     CDS             complement(42464..43222)
                     /locus_tag="VUX16_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET8123403.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSIMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGMIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(43337..45316)
                     /gene="pknB"
                     /locus_tag="VUX16_000363"
     CDS             complement(43337..45316)
                     /gene="pknB"
                     /locus_tag="VUX16_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET8123404.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVMKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRKSSDVIAELKEKKVPDNLIKIEEEESSESEPGTIMKQSPGAGTTYDVN
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVSTAPAGTAE
                     GTVVEQSPRAGEKVDLNKTRVKISIYKPKTSSATP"
     gene            complement(45313..46053)
                     /locus_tag="VUX16_000364"
     CDS             complement(45313..46053)
                     /locus_tag="VUX16_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET8123405.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(46068..47381)
                     /gene="rsmB"
                     /locus_tag="VUX16_000365"
     CDS             complement(46068..47381)
                     /gene="rsmB"
                     /locus_tag="VUX16_000365"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET8123406.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKA
                     LVTELVYGTVARRLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(47374..48309)
                     /locus_tag="VUX16_000366"
     CDS             complement(47374..48309)
                     /locus_tag="VUX16_000366"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET8123407.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELIKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGALFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(48322..50718)
                     /locus_tag="VUX16_000367"
     CDS             complement(48322..50718)
                     /locus_tag="VUX16_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET8123408.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDEEEMEQDLKDIAEVLDFSPVLTQEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHVQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGTLDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEVAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLCYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGLTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(50784..51098)
                     /locus_tag="VUX16_000368"
     CDS             complement(50784..51098)
                     /locus_tag="VUX16_000368"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET8123409.1"
                     /translation="MMLKPSIDTLLDKVTSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(51123..51749)
                     /gene="gmk"
                     /locus_tag="VUX16_000369"
     CDS             complement(51123..51749)
                     /gene="gmk"
                     /locus_tag="VUX16_000369"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET8123410.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQERLVGRGTDSAEVVAQRIEKAKEEIALM
                     REYDYAIVNDQVSLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(51879..53492)
                     /locus_tag="VUX16_000370"
     CDS             complement(51879..53492)
                     /locus_tag="VUX16_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET8123411.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERRKEAE
                     LERIGALSQAEARDIILAQTEENLTKEIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(53616..56603)
                     /locus_tag="VUX16_000371"
     CDS             complement(53616..56603)
                     /locus_tag="VUX16_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HET8123412.1"
                     /translation="MANLGLKERYDFQQWIIKDLRDKNDYIQRDATCYDPRLAMDVEL
                     LWDFLMETQEETMDYLLKKLSKETIVNLINKEIVKGGFLFALKEGVFIENKQLRLLYR
                     KPATSFNEKAVQQYQVNCLSIMEEVVYEESDRIDLVIFINGLALFAIELKFNPSGQSV
                     QDAIRQLKGRNPKNRLFRFEQGVLASFAVDTLEVYMTTQLKGQETYFLPFNVGKGEGI
                     EMGSGNPHNPDGVDTDYLWLDVLTKDSILQLIDSFIFFEMDEMDKHNSKKKTLIFPRY
                     HQRRAVSRLLEDMKVNHTDSNYLIQHSAGSGKTNTIAWLAHSLVSLHDEQNQNIVDTV
                     LIVTDRIVVDRQLQEAVKEISHKPGVVKVMGDKETSSDLADAIAGNTKIIATTIHKFA
                     QINQSNWMSVGNTAKKKFAILIDEAHSSTTGSYMSSVSQVLTETDTEDGTIDEIQEVS
                     VADAIEQEIARTGKQDNVSIIAFTATPKATTLQLFGTTQADGSKAPFDVYSMKQAIEE
                     GFILDVLDNYTTYKTYYKLNKAVEEDPELKTTLAKRKIAKFVELSDENINQKVEIIMD
                     HFISHDIMAELGGQGKAMIVTSGREAAVKYQLAFQKYFKDHSITSIGTLIAFSGKVDY
                     QGSEYTESQMNQVKEDYLKDHFDTEDYQILIVANKYQTGFDQPKLVAMYVDKKLRSVA
                     AVQTLSRLNRIYRGYNKRTFILDFKNTYDDIRSAFSPYYRETILADTVTPSDVLTLDR
                     KIDEYGILDSDVIHEFNQFLYQEKRNSREKQKMVSLLNQGYDRVRRFDEKEQLSIRKV
                     IRGFLRMYTFLIQATAYQNEVLHERYNYLQSLVKMIDVRIGGDDFTIADKIVVDYMKH
                     KQTGSFRSVSELEYHPELILTKPSTGGVTTDQEKRLSEILDEINEQLDLDIDPQVGLS
                     GAVSIRELMKKNPRLKQSARVNSREDFVFAFEEEIDNALIEGYSQSQDLFGALLNNDS
                     FKKRLADIFIDDVFKSLKGSEEV"
     gene            complement(56711..57712)
                     /locus_tag="VUX16_000372"
     CDS             complement(56711..57712)
                     /locus_tag="VUX16_000372"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123413.1"
                     /translation="MVEIYAIGWQVGRGKSLGKLKNFRKVISDEASNYIGNIQFANNQ
                     NSNESTLTLKEKFEESIESLQNVETNGNNTEVPFYRKIDESLQSEIDRIQLVSSQLET
                     DLPPLKNFEDIRLYLVCEEIDGVQYKYFLKSIRVAKLKTRFIATLTSGKVKIVDIEKD
                     EGRSLPFIISYAEKTENNETIQYIFDVQDYEIMFGLNESKIITAEENYKKFLSHNFKL
                     STDFKVKVSDEESEKIKAKLKSHRKLINLLAKYNDEASSYEWKCVKRANKLSAQFFQT
                     PFTFNEKSKEIYLTAESLEAFISVITNAKKLGIAKNEYEDSLADKRQKDKKDNIEVQ"
     gene            complement(57748..58398)
                     /locus_tag="VUX16_000373"
     CDS             complement(57748..58398)
                     /locus_tag="VUX16_000373"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123414.1"
                     /translation="MLFGTDLKFRLAYFFTAFFPAFLLIYFSLVDIHHFLLKETESLP
                     CYLSRNLWHFLMLSVLLSIMLISIYSIRGYINGRRSEENIVKNIVLNFNVFKVTLKNN
                     SQGKVIDIQDGPKINPGFISFVSSTIVPSLVLKFMNGVSALVAIIIIVFFFVLLMLSN
                     DIFPNLILPIFGVNLLVTKDNYNIFFFRKDSAAFSGVKRICTLGNTGTMARTFVFF"
     gene            complement(58401..59672)
                     /locus_tag="VUX16_000374"
     CDS             complement(58401..59672)
                     /locus_tag="VUX16_000374"
                     /inference="COORDINATES: protein motif:HMM:NF013579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET8123415.1"
                     /translation="MTRMKESGIDWIGQIPEEWVISKIKFTTQLNGRIGWQGLTSAEY
                     KEEGPYLITGTDFYNGAINFETAVHIDEKRWSEASQIQVENGDLLITKDGTVGKVAII
                     SGLDDKASLNSGVLRIQTVDEIDRKFLYLVLLSDEFWMWFNYTNSGASTILHLYQNVF
                     DEFTFTFPSKNEQQKIADFLDKKTAQLDKVKALLEEQIQKLKDYRASLIYETVTKGLD
                     KNVPMKDSGIDWIGQVPEGWEISKIRYLVTTRSEKRITDSSIPYIGLENIESQTGKFV
                     ETGIQVDKSENIVVEIGDVLFGKLRPYLRKYWRATFPSTASSEFLVFQSSELDMNFLY
                     YAIQSDSFIEEVNTSTYGSKMPRASWEYIKNMKITFPSSLVEQQKIANLLDENTAQID
                     NLIQIKNQQIKNINKQRQTLIYDYVTGKRRV"
     gene            complement(59665..61773)
                     /locus_tag="VUX16_000375"
     CDS             complement(59665..61773)
                     /locus_tag="VUX16_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009659312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET8123416.1"
                     /translation="MSSFKEKLPLFQANDIQISNDVNTVWSIANTLRGAYRADKYRDV
                     IIPMFVLTRLEAALLPTKDQVVAQYKANPNTPEKVLEKLSGYRYYNVSPFTLENLQND
                     PNAIEENFIAYLDGYSCRVKDIIENLKFKEQVRTLAQSGRLFTVIKKFSQIDLSPSSV
                     DSMRMGYMFEDIIRRFSENEEAGSHYTPREVIALMVNLLLIEADEELFVDKKELKILD
                     MAAGTGGMLATAKSYIRQLNTGATARLFGQEVLPETFGIGRADMLIRQEDSDYFVKVD
                     TLKDPDPFPDTKMSFVIANPPFGQAWGGKDADDGVEDAVKKDHQLFDKTEGRQGRFVA
                     TPGTGDAQLLFHLHALTKLEENGRAAIISNGSPLFSGGTSSGESQIRRYILENDLLEA
                     IVALPGQFFYNTGIGIYIWIYNKNKSPERQNKVQFIDATEEFIPLRKSLGQKRRELSQ
                     DNIRQILRWYDDFQENDHVKIFENQEFLYREFTVMQPLQRRGQISEETIEKAKSVPFL
                     AKLFDEYKYQELLEMEPRSAKDEKKLQDFVAGKIKQEAILTALAKGSSDKTYPDFENF
                     VQVIKDLLGEFKLTPANINALALAMSEMDKTAEVIRTKKKDKANEIADGIVYDKTTKD
                     SEIVKLTEDVETYFAREVYPHVPDAHYWFDEEKGYGAEIPFTRYFYQYQEPESAEKLL
                     AEFYALEAELQTLLEELKHD"
     gene            complement(61989..62243)
                     /locus_tag="VUX16_000376"
     CDS             complement(61989..62243)
                     /locus_tag="VUX16_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HET8123417.1"
                     /translation="MLLKFTEDAWADYCYWQTQDKKTLKRINKLIKDIQSDSFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSIAFLSFKDHY"
     gene            complement(62247..62501)
                     /locus_tag="VUX16_000377"
     CDS             complement(62247..62501)
                     /locus_tag="VUX16_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET8123418.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIVQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(62633..63730)
                     /locus_tag="VUX16_000378"
     CDS             complement(62633..63730)
                     /locus_tag="VUX16_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET8123419.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLEQAEGLKVVAMSGNFMQRGEPAI
                     IDKWIRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILARLGIDTLAFGTEEVLD
                     YQKIADLYTEQEAEMEKFVEKLPDSLSYPQKTQAMWKEFADLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVDKDVDFASATALRQHQSDQDFLERFMPSVALFEQA
                     SKVSWDDYFPMLRYQILSNSDLTTIYQVNQEMAVRIKEAIKPAQSVEDLVKVVATKRY
                     TKARVRRLLTYILVQARESDLSEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDT
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
     gene            complement(63740..64486)
                     /locus_tag="VUX16_000379"
     CDS             complement(63740..64486)
                     /locus_tag="VUX16_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET8123420.1"
                     /translation="MIMATYETFAAVYDEVMDDSLYDKWTDFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRAASAKQKIDFMEGNMLDLSKAGQ
                     YDFVTCYSDSICYMQDEVEVGDVFQEVYNVLNEDGVFIFDVHSTYQTDEIFPGYSYHE
                     NAEDFAMLWDTYEDAAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEVLTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSARWFFVAQK"
     gene            complement(64699..65049)
                     /gene="rsfS"
                     /locus_tag="VUX16_000380"
     CDS             complement(64699..65049)
                     /gene="rsfS"
                     /locus_tag="VUX16_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET8123421.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIADNIREKVAQAGFKGSHIEGDATGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEAHSVDLSETL"
     gene            complement(65050..65643)
                     /gene="yqeK"
                     /locus_tag="VUX16_000381"
     CDS             complement(65050..65643)
                     /gene="yqeK"
                     /locus_tag="VUX16_000381"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET8123422.1"
                     /translation="MAYQDYINCSREALLEKMAELLPEKRLTHCLGVELAAIELAERF
                     GVDVEKAGLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LNLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETVHTVEHLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(65643..66272)
                     /locus_tag="VUX16_000382"
     CDS             complement(65643..66272)
                     /locus_tag="VUX16_000382"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET8123423.1"
                     /translation="MAIELLTPFTKVELEPEIKEKKRKQIGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIEGLAIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(66324..66635)
                     /gene="yhbY"
                     /locus_tag="VUX16_000383"
     CDS             complement(66324..66635)
                     /gene="yhbY"
                     /locus_tag="VUX16_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET8123424.1"
                     /translation="MSLTSKQRAFLNSQAHILKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(66849..67955)
                     /gene="yqeH"
                     /locus_tag="VUX16_000384"
     CDS             complement(66849..67955)
                     /gene="yqeH"
                     /locus_tag="VUX16_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET8123425.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFISGNDV
                     LLVGNKKDILPKSVKSGKISQWIMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPRTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASTFYDKHLGTLLTPPNSKEKEDFPRLVQRVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVIRKAII"
     gene            complement(67958..68548)
                     /locus_tag="VUX16_000385"
     CDS             complement(67958..68548)
                     /locus_tag="VUX16_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET8123426.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYMPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIRIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(68500..69408)
                     /locus_tag="VUX16_000386"
     CDS             complement(68500..69408)
                     /locus_tag="VUX16_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET8123427.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(69465..70025)
                     /locus_tag="VUX16_000387"
     CDS             complement(69465..70025)
                     /locus_tag="VUX16_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET8123428.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVNPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            70164..71369
                     /gene="sstT"
                     /locus_tag="VUX16_000388"
     CDS             70164..71369
                     /gene="sstT"
                     /locus_tag="VUX16_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HET8123429.1"
                     /translation="MKRIIHAWNKASLVKRILIGMLCGGILGLTLPNLSGIGLLGDLF
                     VGGLKAVAPILVFALVANALSQHQKGQDSNMKTVVFLYILGTFAAALVAVVASFIVPI
                     EITLNSANTEIAPPDGIGQVLSNLLLKLVDNPVNALITANYIGILSWAVVFGIAMREA
                     SKNSKELLKTIADVTSKIVEWIINLAPFGILGLVFKTISDKGIGSPANYGILLVLLVT
                     TMLFVALVVNPLIAFFFMRRNPYPLVWNCLRVSGVTAFFTRSSAANIPVNMKLCHDLG
                     LNPDTYSVSIPLGSTINMAGAAITINVLTLAAVNTLGIPVDFATAFVLSVVAAISACG
                     ASGIAGGSLLLIPVACSLFGISNDIAIQVVGGGFVIGVIQDSCETALNSSTDVLFTAV
                     AEYAAARKK"
     gene            71437..72288
                     /locus_tag="VUX16_000389"
     CDS             71437..72288
                     /locus_tag="VUX16_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET8123430.1"
                     /translation="MSISQRTTKLILATCLACFLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFFLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEALK
                     LVYLDHSDHLFHQTDYHIHYFEMRQRQRRILRNMAQQINTCHLAVSESLILAQLFSKI
                     AGQLSQTNPASDLLDEIERYLEVFRNRSLPKTRDEFETRATLLQLLREAKTFIQVKVD
                     FYQKYGQ"
     gene            72431..72811
                     /locus_tag="VUX16_000390"
     CDS             72431..72811
                     /locus_tag="VUX16_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET8123431.1"
                     /translation="MTYLEKWFDFNRRQKEIETLLEDTIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTSD
                     GQKTLASLQKAVETSLETGLDFLI"
     gene            72909..73130
                     /locus_tag="VUX16_000391"
     CDS             72909..73130
                     /locus_tag="VUX16_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET8123432.1"
                     /translation="MIEITYLDASKNERTVTFDSYEDFDRSQQACLIGVADYYPVQKL
                     TYKGYDLDYHGTYGDVFFYLMKQDLSQYN"
     gene            73146..73460
                     /gene="trxA"
                     /locus_tag="VUX16_000392"
     CDS             73146..73460
                     /gene="trxA"
                     /locus_tag="VUX16_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET8123433.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTADQIKAIVAE
                     LS"
     gene            73765..74300
                     /gene="queF"
                     /locus_tag="VUX16_000393"
                     /pseudo
     CDS             73765..74300
                     /gene="queF"
                     /locus_tag="VUX16_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
     gene            complement(74555..75223)
                     /locus_tag="VUX16_000394"
     CDS             complement(74555..75223)
                     /locus_tag="VUX16_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET8123434.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT        21593 a        17005 c        13898 g        22790 t
ORIGIN      
        1 atccttctcc tccctctatt ataccatagt tttaaatcta attttgctag attctatggt
       61 tctatctatt tattcggaaa agaagtgaga aagttaaaaa ctattgaccc taatcacttg
      121 caaagagata tatcttgctc acattattta ttaaaagcta tattttacaa aaaagattac
      181 aaaatcaacc attttagaaa agccttacca ctttctagac tatgaattct agtgttttta
      241 tactcctagc tttctcgtca atatgccata aagcaagttc agttgatcca ttccccatac
      301 tcgttcactc tatagccgtc tggtgttacc gaattgaaaa gtagtttacc caaagcatca
      361 atatagtacc actttccttt ataataaatc catgtattgg attccatgcg accagatgat
      421 cctaagtagt accacgcgcc acttgaatct tggaaccagc ctatctccat cctaccatta
      481 tcattgagat aataccaatt accgtctgta tcctctagcc aaccagtttg catggttcca
      541 ttcgtatcaa aataatacca tgcatcattt tctttcatcc aacctgtccg ttctttccca
      601 tcagaatttc taaaatacca ctgattattt atcttatgcc atcctctttg ttgattatgt
      661 ttaataacag aatgttcaac agtagaaagt aatattttat ccgttttacc gccaaaaaca
      721 gctgttaacg atgacgaacc tgtcccgttc gttgtgaatt gagcagtggt ttctgggcga
      781 gatgatcttt cctgttttga tggagtcttt attttactct catttcggtg cccttctact
      841 gtcaattttt ctccacctgt aactttagtc acaaaatctg gaacttctac tctttcaggg
      901 actagttctt ctgaagatac tataagtatc ccaagatctc cttgtatttt ttctcctgat
      961 actaaagcat ctgactctga aaatccctca ctaagcgcag gctgctcttc tctaatcggc
     1021 gcatcttttg gaactagaga ctctacttta tctggagata ccacttcctt cacaccctta
     1081 cgaactacac gctctctcat gggtgtaacg tcaactgtac gagaattttc aataaccttt
     1141 ccatcaggta aaaccttata agtaaccgta gtaacctctt tacctacaga accttcagaa
     1201 ataacctcag ttttaccttt ctctagttct gcggaatctt caaaacgttc tgtaattgga
     1261 acttcttttg tgctgctatt tttcttaata cctaatgtga tgacttgaga ttgaggtgct
     1321 attttctctt cagaaatctt ggaggatacc gctcctgtgt acttatctac ttggtaactt
     1381 gtagtgcgag taactagacc ctctttaccc tctaaaactg aacggaaacc aagctcttta
     1441 gtttcatctc cttggtaaac cgtgtcaaag gcaataggtg acatttctgt tttcgattta
     1501 gtacctttat acaccgttcg ataaataagg gaaacacctt ctttttcgcc ctcagtttcc
     1561 tctgtacgct ctttcccaac ttcaagggta ctatcaccct cataactcgt tataacctct
     1621 gttttcggct tttcttgcgg ttttagaggt gtatttggtt tatctttatc cgactctact
     1681 tttggtgtgg tcggtttttc ttcttttgaa gttgatggaa gtttatcctt gtctttttca
     1741 tccaccaaaa tattatctgt tacataaaca ggggctttgg gtttaccctc aatataggaa
     1801 cgaacccaat ctaattgttc ttttgataag actaacccac cactgcggct tcctacaaca
     1861 ccattttggt gaactccaat taaagaacct ttgtcattat aaagaccacc accagaagct
     1921 ccgggttttg taccaccata gctaatccct tcaatacctg aaccaaagtc agtagtagct
     1981 actacttcac tatccaaaac tggagacaaa cgaccatcag gaaaaccata aacggaaact
     2041 ttgtcacctt tagtaatcga agttgactca gataccacct ctacaggaga taccgctgta
     2101 agcttttctt tcaaacgaac caaagctaag tcatttttaa atccaaatac tgagtctttc
     2161 ttgttccaat aaacaatatc atcatcggaa aaattcacag gctgaccact tggcaaagta
     2221 gctttataca ctgtattggt gcgaccagac ttcgtaacta cctcagaacc tttaactgtt
     2281 aagaaattat gagcgactgt taacaccaaa tttggtgcaa ttaaagtacc tgaccccgac
     2341 ccatctggcg tttgaatatg cgttgtagca tagaagtttt ctgaaccatt cggagcttgt
     2401 aatacctctt tactaggcac aggtaagttc gatttaccac tcaaatcaac cttaccaact
     2461 tcagttcttg caaaatccga agaagacgta gatggaggag ttaccgaatc tactaccgct
     2521 cttataattg tatcacccaa agctaactta ctgacatatt catcagacca acttgtatca
     2581 cttgctaatt tgttaattgg cactccgtta taggatacca ctttagctgt tggagaagtt
     2641 gctattaact gtttgaagtt tggattttgt cttaaatgaa aattcaaacc acttccaaca
     2701 gaaccttctt gaacaacctt atctgaaatc aaaggagttc ctttagtatc ttccactcga
     2761 agtagaacgc gacctttttc ttcaccctct agtaaagtag ctcggccttt ttcatcaaaa
     2821 cgatacaaag caccgtcaat ctcagactct acatctttta aggctctgtg attttcatca
     2881 tagtagtaac ggtttgcacc atctatatac caacccttta taccatattt atcaatcata
     2941 gaacgaatcc aagctctgtg cttttccgta aagagggtac caccaccaat acgctcactt
     3001 tcttgagcgt ttggagtatt tgtcccatgt tggtggatac cgactacctc tcccttatca
     3061 ttaaacaaag gagcacctga aaaacctcct aaagctgagg aatgataagt gactgtacca
     3121 ctctctttat tgacactact tacagttgtt gtaactgaat aagccttacc gtctttcaat
     3181 cgtgctttgt tttctgcact taaattcgga gttgaaaagt cattaggata gccgaccata
     3241 gagattttat caccagtaga aacctcttta tggctcaatt ctcttggtga atcttcacca
     3301 cctgtcatag cttctacagt ctttttagtt accactactg ctaagtcgtt gctatagtct
     3361 ttcccaaaat ttttctcatc atacaaatga atagagtctt tttcaagagt ttctgataca
     3421 ccagaagtag gtactttatt gtgcttttcc gtctctgagt tcatcacaac ataactacga
     3481 gcagacgccc caccacgcaa gaccgcagac ttatcctctt ggtttttatc atagtagtta
     3541 tgagctactg ttaccatcac attcggcgct acaaagacac cgctacctga tgcggtttgt
     3601 tttccacttg ttccgctatc ataagtggta taggtcatag caacaccttc cgcagattta
     3661 ctatgaacgt tcacatcttt tatatcgtta ccaccctgaa taacatcagc agcaacgact
     3721 ccaccaccaa taactggtaa gtctggtgca gctaatccaa tcatactcac taatgccaga
     3781 catcccacca acccgtaagc ttttgactta cgatatttac ctaaaccttt taaatataaa
     3841 aacatctttt cctcacttta gtttctaata cttatttatc cagatataat agcttataat
     3901 cttttaaaat cttcaaataa gttatgattg ttccatactc ttcaaaccat gtcatcttcg
     3961 tcttgccgta tgtatatgtt actgacttcg tcagttctat ctgcaacctc aaaacggtgt
     4021 tttgagctga cttcgtcagt ttcatctaca acctcaaaac ggtgttttgg gcaggctacg
     4081 gctagcttcc taatttgctc tttgattttt tgagtataag gacatattgg attctatgtg
     4141 ctatattgtc aacaatacac tcttcttcct gtatatctac caacatgaat tacagaattt
     4201 tattttacta taattttacc tatattccaa gacaagaaat aaaataatca agaacaaaaa
     4261 cgcatataac caataactag ctatatgcat tttaacactt aaagcgaact gttaaattgc
     4321 gactagtagt atccagtcgg aagtaagtcg gaaatataca gtttatttac gattagcaag
     4381 tcatttaccc ggcaatagaa gctcatttaa attgattttt ccttagagta gaaatctcta
     4441 cgaaaactat ctaaataaac ttttaatctc tatgacgaat aaaacgtgtc tcagttattc
     4501 atcaacatcc aagtctctag tagttgaccc actctccatt ggagttaact tgataaccat
     4561 ccactatggt attaacagct aatcttccgc tttcattgac atagtaccat ttgtctccaa
     4621 cttggaacca ttgatttacc ctcattgcac cagatgattc ctgatagtac caatggtctc
     4681 catcttttat ccaaccagtc gccattgaac cgttagaatg gagatagtac cacacaccac
     4741 tggattcaac ccagccagta gacattgctc cactctcact caaataatac cattgattac
     4801 catctctgac ccaaccagtt gccatcgcac cagtagaact caagtagtac catttatccg
     4861 cttcctgatg ccagcctttc accacttcac cagcagatgt ataaaaatac cacgcaccat
     4921 tttcttgctt ccaaccagtc gttattggaa ctttagtctc agttttaata acatctccta
     4981 cataagattg gaggtaacga ggagcaaaag aagtaagagg agagtttgct accattctat
     5041 ctgaagactc caaagataat ttatccttct ctgacttcct ttctgtcatc tcctcagata
     5101 cattttctct tactgtattc atggtctcga caggattttc tttcgcatct tcaggaattc
     5161 tactaccagc tagtgtaact ggtaaatcat gcatactgtc aattctaccg gccattagac
     5221 ctgtaatttc ttgacctgca tcttctttat taaaggtgaa aagtagagtt ttttgatctg
     5281 cttgggtcaa gaaggtagct ttgtgtccat tcgctaaagt caaagtcgga atagcattca
     5341 ctagtacctc agaatcaaat tgcatagcta agatgccttg ttctgcatcc tcttcttctg
     5401 tttccaattt acgaacgtcc ctgatagtta cactcgttgg atataccggc tcctttgtta
     5461 aaaagtccca attaaatttt ctaaatgata gggtatagtc attttgtcct ttttcagtat
     5521 gttcatacaa gataccatac tccccatttc ctaattcttg aagcgaatta taggcaaact
     5581 ctcctttttg aattggtcta tgatgtaacc caagtcaagt ctccgttgtc ctctacacga
     5641 gccaaatgag ccattccatt cgtccgttta ggtcctcctg aattggttaa aatgatatat
     5701 tcttttcctt cgtgcatggt gtgaatagca gccatttgga cataaacatc tttaacctga
     5761 ttatatctct tgatttcctt gtcccaagtt tgcccaccat ctttacttgt ggcaacctgt
     5821 aaatcacccg ttaaccctct cataaagagt ttcacatcac cattatttaa ctgcacagca
     5881 actgactcag tattttgggc attcctatta ttcatagttg aggaatgaat tttccttctg
     5941 cctaccgtcc tatcatcatt aacagcagct ccagcctgcc atgtttctcc atgatcatct
     6001 gaataaatca aacgtgaaga ctgggagccg cttagatggg agatagcatt ggtggtataa
     6061 gtgggaacta ggatacgtcc cttgtgctct cctgttctaa gcacaattcc tgtacctgga
     6121 cctgttccta aaaatttcat ccaatcttgg cgaattgatg gtgtaatatc tcttggttgc
     6181 gaccaagctt tcccatcatc atcactatag gaaagccaca aatagctcgt ataggctaca
     6241 cgaaatggag ttttagcaga ttgagcaaag tagatattcc caagaagctc ttctccttta
     6301 tagaggtcgc ccttatctct ataggcttct tcttttggat ccactacaac gcgataatct
     6361 gttttttgat tatttgcatc atatacttct tcgttttctc gaacagtata tgcttgattt
     6421 tccccttgtt tatatagtaa ttgatagtgc ttgtctccaa cttgttgata agctttttga
     6481 ggtttgtttg gcattccaaa gacagctcga ccctctggaa acatatcgta gattgaaaaa
     6541 attctctttg tggtaggatc ttgaaccaag accatatcga tattaagtgg agatgatgcc
     6601 tgcggatctt ttgcttctgg attgtctcgc aggttggtca aggttaaggt tggctgccaa
     6661 gtagttcccc catcctcact tctcctaacg accatagcaa catctcccca atcagaatgg
     6721 tggagacgac gctgatctgc ccctgccagt aatgttcctt tatccgtacg tagcaaagct
     6781 ggaatccgat aactcttaat tccctcacta tttggcttac cattgacatc actcataaac
     6841 aactcttgct tctctgtcaa gactgcccct tcagcaagta aaggctcaat atctatcaca
     6901 tcaaacaact ggctacgttt tttgacttcc tctggagtta gagcacgatt gtatacagtc
     6961 agattacgaa tagaaagatc tgagctccac ttcagttctc ctgctctatt agttgcacct
     7021 aactggagtt tatctacatc tggcatatct gccaggaatt tccctgactt tttattcgta
     7081 cgagataata caccattcac ataaagacga acctgaccat ttggactatc ctttcttggt
     7141 ctttcaacag taaaagtaac cgaattatac ttgcctggtc taatcttcaa aggcgcatct
     7201 gtataacttc cataaaattg gctaccatca gctccacgtc cctctatcaa agctgtccca
     7261 ttattgattg ccattgtaaa gtattcattt actttagttg tactggaagc agaaaagaga
     7321 ttgtaaaaac taggaccatc agcagccggt ttgaactcca catgaacagt tgcattttgg
     7381 agtcccttta ctttctccaa tcagactcct gccaatctag tttatctacc aggacaccgc
     7441 tgcaattaaa ctaaaatatc tctttataag caaatgatgg acatcagctt atgctattta
     7501 caccatactt cctgctcaat ccttatcgaa cactttttca aatagctttt cataagcata
     7561 aatacttgta gaaataatgg gaaatataat caagctcaca atcagaatct tatccagctt
     7621 aaaggggaca atcccaaata agtgaagaaa taaatcaatc agaaaactgt cgaaaaaaac
     7681 tgtcaaaagt agttcaactt gtctttttct ctgctttttt gtcttgaatg ccttaaatat
     7741 catattattc cccttttcta agcttcaatc ccttctctct atctgttatt tcgcatagct
     7801 actactattt ttacagcaat ctatctttaa atatacataa agatagattc tatcactttt
     7861 tataagtgtt agtaaattta ttatacctca tttttaaaac gctttcaata tagtgtagta
     7921 tagtagattt tagtttcaaa aaactctttt atataataat gtccttgaaa gtagtttcag
     7981 ctgaacattt atagttcata aaaagaaaac agaaactcat ctgttttttt acactcaatg
     8041 aaaatcaaag accaagctag gaagctagcc gcatgatgct caaaacactg ttttgaggtt
     8101 gtagataaga ctgacaaagt cagctcaaaa caccgttttg aggtggcaga tagaactgac
     8161 gaagtcagct caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat
     8221 acctacggca agacgaagct gacgtggttt gaagagattt ttgaaaagta ttaacaccta
     8281 cagacaagcc tgacgatagc aagaactacc ctactcgata ggtatcggct tttgctttct
     8341 gaaaaaaatt attttaagca atttgacaaa tctagcaaca aaaaattcta taaatataat
     8401 atattgaaac tagaatagta cacatctact tctaaaacat tgttagaaat cgatttgact
     8461 gtcctgatcg atttatcctg ttcttgtttc attttactat atttccatga taaaacgcat
     8521 agtatcaagt cttcttaatc ccctgatact atgcgtgttt gtgattttta agattttgtg
     8581 cctagagtcg actccttatt ttagatattt gaaaggaatc tcactcccac agagccagtt
     8641 ataaacctgg tcattgacaa aaacattcat ggcttcatgg gcatactcag gcatgatgcg
     8701 ataagcctta tcgcaggtca aacgattgta aatcgcaaac tgggtaatgg gatagcaaac
     8761 atcgtcatcc aaacccgtaa tcatcttaac ctcacccttg atacgatggg caaggatcgc
     8821 catgatctcc tcctcagttt catggaaggg gtcgtaaaat ttgaaatatc taaaaagttc
     8881 gtcataggct tcgctagtat taccaatctc aagcactcgt ctgaagtctg acaagaaggg
     8941 atagatggca actggtttct gaattcgagg attgagcgct gctgcaacca aagctagagc
     9001 ccctccttgc gaggcaccat agctggaaag tcgcttctca tctacctgag gcagactagc
     9061 aataatttca accaactggt aaatgtccag ataaacatcc ttataaaaga ggtggtcccg
     9121 accttccaca gcaccacgga tgatatgtcc cttaacggta tttccaagag gagagcgcaa
     9181 accgtcttgt gaatagcccg actggcctcg aacatccatg gaaacaacac cgtaaccagc
     9241 tacggtgaaa gccagcatgt cggcccaatc ccaaccacgt cccatataac catggaaatg
     9301 gaagattaac ggaaccttct cctcactctt tggaagaaca actcgtgcat agaccttgcc
     9361 ttgcttgctt ccttcaaagg ttagctcata gcacttgact tgagaaatgt ggaaatttat
     9421 ttcctccaac tggtaggctg gaagcgtgga aacttttttc acttcctcat cccagaaagc
     9481 atcaacgtct tctggaacct cgtcccttcc tagatagatc ttcatttctt ctaacaaagc
     9541 tggatttttc atagcatgct ccttttgttt tgtaatcgct agcaccactg tagcacatct
     9601 aagaaagcaa tgcaagaaag aagggtaaat agaaagtgaa tttagctttt cttccttcaa
     9661 gcctattgac tgaaagtagt tttagaaacg aaaaaagagc atttccgccc tttttcttct
     9721 gctcaatctt aatctgttgc ttctttcttt tgaaaagtgc ttgggtaatt tactttaatc
     9781 gttactgtca tatgagagtc ctcgtttctt tttgatgact ctagtataag ggccaaacct
     9841 gaaagctagc ttaagttttc cttagagaaa gcttaatcca gatgttcttt cttttccaga
     9901 tgaaaggcaa tcatgcgcca ctctggatcc tcttgccagc cttcaataga actaatgtaa
     9961 ctaacaactt ttctagcttc ttctaaaatc ggaaaatctt cgataatatc agccacttgg
    10021 aactctggaa gtcctgactg tctggttcca aaaatctcac cagaaccacg cattttcaaa
    10081 tcttcctccg caaggacaaa tccattggtc gtttctgtca tgatgcgcat gcggtctttc
    10141 ccagaatccg tcttgggatt ggcaacgaga acagcgtagg actgcttgtc cccccgaccg
    10201 acacgacctc tgagctggtg aagctgacta agcccgaagc gatcggcatc catgatgatc
    10261 atgacagtcg catttggaac attgacccca acctcgataa ccgttgttga aaccagaata
    10321 tctgtttttc tctccttgaa atcctgcatg atctggtctt tttcgtcact cttcatctta
    10381 ccatgtagaa gagccacttc tgccttacct gcaaaatgag ccgtcagctc ttctgataag
    10441 gcaatggcat ttttcaaatc tagagcttct gattcttcaa tcaaaggaga gatgacatag
    10501 gcttgggaac ctttttgaat ttccccctct aaccaagtca agacctgagg tagttgctca
    10561 tgtttgatcc agcgcgtcac aataggtttc cgacctgctg gcatctggtc gataatggaa
    10621 acatccatat ctccaaaggc tgtgatggca agcgtccgtg gaatgggagt cgccgtcatc
    10681 atgaggacat ctggattgtc gcctttttcc cgtaaaatac gcctttgccc cacaccaaaa
    10741 cggtgctgct catcgataat aatcaaacca agacgagcat actccacccc atcttgtatc
    10801 agagcgtgag ttccgataat caaatcagcc tcacccttgg caatggtctc caagacttct
    10861 ctcttttctg cagctttcaa ggaacctgtc aagagagcca gtttcaaatt gggaaaaagg
    10921 ttctgtaaac tctcaaagtg ttgctctgcg aggatttctg ttggtaccat tagggcagcc
    10981 tgataacctg ctgtcactgc cgcaaacatg gccaagccag cgactaccgt ttttccgctc
    11041 cccacatctc cttgtaggag acgattcatg tggtggtcgg acttcatatc aattaaaatt
    11101 tcctgcaaac tcttttcctg agcttgggtc agggcaaaag gaagacttgc tttaactgct
    11161 gtcacttttt cctgagacca attcagaacc agaccacttc cctgaactct attttcagac
    11221 ttgagcgtct gcaactgcat ttggaaataa aagagttcct caaacttgat acggcgaaga
    11281 gcctgcttgt attctgccaa atcctttgga aaatgcatag ctcggactgc ctgacaacgg
    11341 gacatgagtt tgtatttgtc tagtaaagac tggggcagat tttcttctat caagaggtcc
    11401 agtccctgat caaaagccgt cttgatgacc ttaaccagac tggcctgact gattccctga
    11461 gccagacgat agacaggctg gaggtcatct tctacctgag ccagaacctt catcccagtc
    11521 agactagcct tagcgcggtc ccattttcca aagacagcaa gggttgctcc caactctatt
    11581 ttatcagcca gatagggctg gttaaagaaa ttcaccgcaa aaacgacctc tccctgcttg
    11641 agactaaaac gcaggcgatt gcgcttgaaa ccataatact ggacactagc aggagtcact
    11701 acctgaccag aaagaactgc cttctcaccg tcttccagct ccagcacctg cttggttttg
    11761 aagtcttcat aacggaaagg aaagtagagc aagagatctt gcaagttttc aattcctagt
    11821 ttggcgtatt tttctgctga ctttagtccc acaccaggta agacatgcaa gggttgatgt
    11881 agattcatgc tccactcctt tcttttctaa taatattctc tcggaatacg gtcgctgagg
    11941 aggcaaacca cctcatagtt aatggttacg cggtaggtcg ctacctgagt tgcagtgatt
    12001 tccttatccc cattggagcc aatcaaggtt accttggttc cgagtgggta aggcttaggt
    12061 aatcgaatag tgatttggtc catcgaaacc ctgccgacaa ttgggcaagc ttggccatct
    12121 accaagacag agaaattctg catgtctctt gtccatccat ctgcataccc gattggcacg
    12181 gtcgcgatga cttgctcgct atccgcttga taagttgctc cataacccat gcaagctcca
    12241 gctggaactg tcttgacatg aaccagagca gactccaagg tcaaggccgg tatcaaatca
    12301 taaggcaaat ccaagaccgc tccacttgga ttgagaccat acatggcatc tcccatacga
    12361 accgcattga aaatagtctc tacatgccaa agagtcgttg cagaattgct agcatgaacc
    12421 agctctggaa cttccttcat actagctaaa atagttttaa accgttctaa ctgggcatta
    12481 aaatagtcat ctgattcctc atcagcagta gcaaagtggg taaagattcc ttcaacacaa
    12541 acaccgtgtt gttggagcaa atcttgagcc tgctcaacct cactggcctc tctaaaacca
    12601 atccgtccca tccctgaatc aatcttgagg tggactgtca atccagttag gtccacttcc
    12661 ttatctaaga gtgcttgaat ccactccagt ccagccactg tcaaggtgaa gtcatattct
    12721 ttagctagag caacagcttc gatttcagaa actcctaaaa tgaggattgg cttgctgagt
    12781 ccagcttgtc tgagttcaat ggcttcatcg atattggaaa cgcaaaagcc atcaacatca
    12841 tcttgaattt ccttggcaac ggcaacagct ccatgaccat aagcattggc cttgaccaca
    12901 gcccacttga gcgttccttg agggatatga gcccccattt gctgaatatt ttgtcgaata
    12961 gctcccagat gaatcagaac cttggttggt ctatgtggac tagctttcat gattttcctc
    13021 caaaatgaca ctggctgtca caaactgatc ggtgtggctg atagacagcc aaatctttcc
    13081 tgaaaatggt gcctgactaa aataaggcgc cccacgttca ttgttcaaga cttccaaatc
    13141 ctgaaaaccg agcttgctaa tgcccgttcc catagccttg gaaaaggcct ccttagccga
    13201 ccagcgacca gctaaatatt ctatttgcct gcgtcctttg agactggtga agcgctccat
    13261 ttcctgagcg gtcagtacac gcttagcaaa tccttcatgt cgtgtaactg cgctttctat
    13321 cgaagccaat tcttcgatgt caattccgtg tccaactatc attctcatca aaaggagttg
    13381 agattcccca actccatcct tttcacttat tttgtcaagg taacataaat ctcttctacc
    13441 aaggcctctg tattttccca acctaggcaa gggtcagtaa tagagcaacc aaagacctct
    13501 ggttggtttt gacgaccatc tgctaggtaa gattcaatca taaatcctcg aaccgtcttt
    13561 ttaattttct cattccaatc acgattctgc aaggtctggc gaacaattcg aatctgctcc
    13621 atatattgct tgcctgagtt atcatggttg gtgtcaatga ggataaaagg attttcaagt
    13681 cccatggttt catagcgttc aatggcttgg agtaggtttt catagtagta attcggcata
    13741 taattaccat actcgttgac tgctccacgg aggataacat gggccaaagg attacctgat
    13801 gtctcaactt cctgcccatg ataaaggaag gtttgcttgt tttgagcagc atagatggcg
    13861 ttaaacataa cacccaaatt tcctgaggtt ggatttttca tccctactgg tgcatcaatc
    13921 ccagaagcca caaagcggtg ctcttggtct tccacagaac gagctccaac ggcatggtag
    13981 ctgaccaagt catccaccaa gatcagattt gacggataaa gcatctcatc tgccgttgtc
    14041 aaaccagtct ctgtaatcac gcggtagtgc aactggcgca cagcctgcaa gccgttaatc
    14101 aggcttggag ccttagaagt atctggctgg tgaaccaatc ctttatagcc gtctccattg
    14161 gtacgaggct tagcagtata cacgcgcatg accatgaaaa tcttgtccgc taccttcttt
    14221 tgcaaggcgg ataaacggcg agcatattcc aagaccgcct cttcattatc agaagagcaa
    14281 ggaccaatca ccaagagaat acggtcatct tcccctgaaa taatatctgc caattccctg
    14341 tcacggcttt ccttgagtct caaggcttcc gcagacaatt gggtttcagc cttgatgact
    14401 tccatatcga tttcttgacc tttttcaata aatgccatct tattctccta acgttttgta
    14461 aatttctctg acaagagctt ctgtgttatc ccaacccagg caagggtctg tgatagactt
    14521 gccaaatact tctggctcat tttgtcgacc atcttccaga taagactcaa tcataaaacc
    14581 acgaacgaac tgcttaattt tttcattcca agcacggtta atcaaggtct ggcggacaat
    14641 tcggatctgt tcaatatact gcttaccaga attgtcatga ttggtatcaa tgatgataaa
    14701 aggattttcc aagcccattt tctcatactg ggcaatggta tcaattaaat tgtcataata
    14761 gtagttggga atattttttc catactcatt aagagcacca cgaagaatag cgtgtgaaag
    14821 cgggttccca gttgtttcta cttcttttcc taagaaaagg aaactttgtt tgttttgagc
    14881 agcataaatc ccattaaaca tgacattgag atttccagag gttggatttt taaaaccagt
    14941 agaaaatcct gccccacttg ccacaaagcg gtgttgctgg tcttcaactg aacgggcacc
    15001 aactgccatg taagaaatca aatcatctac aagcggaagg ttttcaggat aaagcatttc
    15061 atcagcagtt gtcatccctg tttctgtgat gacacgatag tgaagatggc gaacggcttt
    15121 gattccattg ataagactag gcgcttctgt cgcgttaggc tggtgaatca agcccttata
    15181 gccatctccg ttggtacggg gtttggcagt ataaacacgc ataaccataa agatacgatc
    15241 tgccacttct tcttgtagga ctgccaaacg cctagcgtat tcaaggacag cttcttcgtt
    15301 gtcagatgag catggcccga ttaccaagag aattcgctgg tcttctccac gtataatggc
    15361 ttctagctct tgatctcgct gtgatttcct ctccaaagcc tgaccttcta attttgacaa
    15421 ggcacgaact tcttctatat ttattttaga gctttttgct gtaaatacca taactcatct
    15481 ccttataaag caaacggata cccagtaaaa atttactttt cacaagatat ccgcctctaa
    15541 actatctcat tttattgtct tttaccgtga cagtttttaa atttcttacc agaaccacat
    15601 gggcaaagtt cattgcgtcc aatctggctc aaatccaaat cttctggcat acttgcttgg
    15661 tgagcagcga tattgcgagt cgctgttgta ctgatatgac gttctgcctg tggtctttct
    15721 tgttcatgaa tttgtgcttt catcatcaag cgtgtcacat caaactcaat cgaaccaatc
    15781 atatcattaa acatacggaa accttctgcc tgatactcaa caacagggtt gttctgagca
    15841 tagccacgaa gtccaaccgc gttacgcaat tgatcaaggg catcgatatg atctgtccac
    15901 ttgttatcca ccactcgtag aatcaaaact ttttggaatt ctttaactgc ttcttcatcg
    15961 cgtagttttg aaacctgact atcgtaaacc ttcaaggcac gttggaaaag ctcttccttg
    16021 atggccttat cagacaagcc tgacaagtct tccatcgtaa tagaatcttc aggaagcaag
    16081 ttgtacttag caaagttcaa gattgcctct agtttttcat cttgtttggc acgcgcatga
    16141 ccatcaacga cacgttcaat cgtgcgtttg atcatagcct gaatttcagg tgccaagtca
    16201 cgatctgcag tgatgacatc gtaacgttga gcatagataa tctcacgttg ttcacgcatg
    16261 acatcatcgt attgaaggac ttgtttacgg gtatcgtagt tatttccttc gacacgtttc
    16321 tgagctgctt caacctgacg cgtcaacatg cgagactcaa tggcctcttc agacatgttc
    16381 aagcgttcaa agattccctt caagcgttca gaaccaaaac gtttcatcaa atcatcttca
    16441 agagataggt agaattgtga ctcacctgga tctccttgac gacctgaacg tccacgaagc
    16501 tggttatcga tacgacgact ttcatgacgt tctgtaccaa taacacaaag tcctccaagt
    16561 tcacgaacac cttcaccaag cttgatgtcg gtaccacgac ccgccatgtt ggttgcgatg
    16621 gtaacggcac cacgttgacc agcattcatg atgatttggg cttctctata gtggtttttg
    16681 gcattcaaga cttcgtgagg aacaccagct gcgaccaatt tcttagaaat gtagtcacta
    16741 gtttcaaccg ctactgtacc aaccaagaca ggttgaccct tttggtaacg agccttaacg
    16801 tcttcgacaa ccgctttaaa cttagattca atacttgcat aaagaaggtc tgagtggtca
    16861 atacgttgaa caggacggtt tgttgggatt ggaataacac gaatgttgta gatttcacgg
    16921 aattcttctt cctcagtctt acctgtaccc gtcataccag acaatttctt gtacatacgg
    16981 aagaggtttt ggtacgtgat tgaggcagat gtcttggttt catcctggat tggcacacct
    17041 tctttggctt caatagcttg gtgcaatcca tcagaataac gacgaccttc catggtacga
    17101 cctgtaaatt ggtcgacaat caagatttct tgctcttcgc tcaccacata gtcaatatcg
    17161 agaagcatga tgtagttggc acgaagggcg ttatcgataa agtgagtcaa agccacgttt
    17221 tcaatgtcat agaggttttc aagtttgaag tagctttcag ccctgtcaat ccctgaatca
    17281 gacaaaccaa tagtcttaga ctgcacatcg atgatgtagt catctttgtt caaagatttt
    17341 acatagtggt ctgccatgtg atacaactga ctggtttcaa ccgcattggc acctgataca
    17401 atcaaaggtg tacgagcctc gtcaatcaag atagagtcaa cctcatcgac caaggcatag
    17461 ttaagcggac gttgtaccat gttttcagcg cgaacgacca tgttgtcacg aaggtagtca
    17521 aatccgattt ctgagttagt tgagtaagta atatcacact cataggcttc ttttttctcc
    17581 attggagatt tggtagccaa gttaatccct actgacaaac caagccaaga gtacaattca
    17641 cccatctcag tcgcgtcacg ttctgacagg tattcattaa ccgtaactac gtgaacccct
    17701 ttacctgaaa gggcattgag gtataccggc atggtcgcag tcaaggtttt cccttcccct
    17761 gtacgcatct ctggcacgtc accatggtga agaacaatcc cccccatgac ctgaacctta
    17821 taagggaaga gacctaggac acgtttggca ccttcacgga caaccgcaaa tgcttcgtaa
    17881 agcaatgaat ccagtgattc tccattttga taacgttcct taaattcaac tgtttttgct
    17941 tttagttggt cgtcagtcaa agcagccatt tggtcttcgt atttgaaaac cttgtcagcc
    18001 atcttttcca gacgacggat ttctccttta tcattttcga taattgtttt taaaatatta
    18061 gccatgtttt tccttacttt aaattccgaa tattttagaa tgttccttta attttagcac
    18121 aattactgat tattttcaag gaagaatccc cattttgaaa aggaaaaaga ggttagtttt
    18181 caagctaacc tctccgactt ttatgactgt ttaattgcca aaaatcggca aaatggcaaa
    18241 tgtgataaat aagttaatcc aaagagaaag acagcaaatc agtccaaaaa caaagagact
    18301 gactttcttg gacagcaagg ccatgagaat ggacagaatt ccaaaaacta gcaagacttt
    18361 ctgtatgatg aagatgtcaa tccttacccc cagaatcgct ctatcccaag ggaaaaagaa
    18421 gaaagtcagc cagatcagca gaactaaacc aatataaacc ttggaatagc gtgtaataaa
    18481 tgattttaga tgtgccataa gccatctcct aggattgtat atcctttaca tattgtatat
    18541 gtccattttc gacaactaat acatctgtac aaaggtctga aatatcttcc gatatgtgcg
    18601 acgtcaggat aaccagacca ttttcttttt tcaggtaaga taaaatgacc tgtttggtta
    18661 acctcacact cttctcatcc aaagcattca taggttcatc gagaaagagt atagaaggag
    18721 aggaaataaa ggcttgaatc aaggccattt tttgctttgt tcctaaggat aaatgacggt
    18781 attcaacgtc ttcaaattcc tgtaaatcat agtattgaat ccaataggca attctttttt
    18841 ccgtaacttt agatgaaaaa taccttaaca gttccaaatt ttctctcagg gataaatgag
    18901 ataaaaactc gactttttca attaaaattc ctgcatcctg aatataatga ttttttatcc
    18961 cgtagacttt cccgtcttga agaacttttc ctttgtcaag cttaatataa ccagcaagta
    19021 tctttaaaag aaccgtcttg ccagatccat tatcaccttt aagtccataa atttttcctg
    19081 attgaaacac caaattcaac tgatttaaaa taggtctttt cccataaatt ttctgtccat
    19141 ttataatttc aagtctcatc gtttatcctt tcttaaattt ctcttccaag cgactaacaa
    19201 tcaacataac taataaactt aaaagtacta aatacactgt tacaatatga tccatcatcc
    19261 attcttgtcc cacaaatgct aaaaaataga gaaaaaagga aaaaccagcg cccgcactaa
    19321 tcagtgctat cagataagac agtagtaagt acaacatcat taactgagca agtaaaaaga
    19381 aaagtgcgac tgttttgaaa tgaattccta taggaagtaa accaagaaac cagacaaaca
    19441 aatcttgagt aaaaaattta gaaatgacaa ccaatcgttt ccttgtataa tctaaaaagg
    19501 agcttgattg atagcgaatc aagtgatggt aatgatctgc caaatcactt tcaagtaaaa
    19561 tgacagagag ccatcctacc atgaaaagcg aaaggtttaa caagagtttg gggatttcta
    19621 aattcgcttc agaatagtca ttataggaaa agattgaaat caattctctc ttgaaaaaga
    19681 taacagcatc ctgcttttga accgctgttg acaatagata gtttatcaaa atcatcatca
    19741 gaactatacg aagtagtaaa acaatctttc tctttagcaa aatattgtta aaattcttaa
    19801 acattatctt catatttttc aagaaccata taagggacaa tataaaggat ataaggagta
    19861 aagagtttca tcaaacttac atccccatag ctagcttgca tcaaactcgt cataggaacc
    19921 atatagtaag gcaaggcact atagagtaac atagaaccaa gccaaagaaa catcaaatag
    19981 gcgattgccg aacgagtcac atttcctaaa taatcaacta ttttaaaaaa atagactgca
    20041 ttgatgaaaa taccgattag taggacacaa gtaaagaaca aatagcttgt tatctctcca
    20101 tctaggagcc tttgtaaact actcccgtca gaaaatagag aattccatcc aagaggagaa
    20161 aaagtcccaa agaaatgagt taaaattgca attatcagca cagtcactaa atatattaaa
    20221 caagggatac ttgcaacttg caaagtcaac tttcttttta gcccttgata gctcacttct
    20281 cttccaatac tcaatcgtaa aactttattt ttcagctcaa tatattgaaa acctagcaaa
    20341 acaatggtga ttggaataat aaatgattga taaaaaccta gattgaactg gagaatacga
    20401 aaatctaatg ctgattttaa taagtcattt ttaattgctt gtccatcgaa tttagctaga
    20461 tcgggcgcat gaatatcaaa aaagaaataa gtcatcaaaa catcacgata aaccaaagta
    20521 agaaaaagca aagtaagcaa gacataaaca aatttatgcc ttgcaaaagt taagagagga
    20581 atcttcataa gccacctcct acaaatagaa agtaatataa tactcaatga aaatcaaaga
    20641 gcaaactagg aaactagccg caagttgctc aaagcactgc tttgaggttg tagataagac
    20701 tgacgaagtc agttacatat ataatccaag gcgacgttga cgtggtttga agagattttc
    20761 gaagagtata aatcaatgcc ttccgccttt agacttccct agttcccgtc tcaagtcaag
    20821 catttttttg aaacagatat agtctaacca gtcactagca aaagcgataa gtagtaataa
    20881 tagccaaata ccccataact tgatatctgt caaatttctc aagacgatat tgaaaaacag
    20941 aactgaaaaa actgtctaag caaggctaaa aagagcatag agggtgatgt aaatccagta
    21001 aaaatagtaa aaaattggga aaaatttact ttctctatta tccttgtcaa tccagctgaa
    21061 aaagtaaaaa cagggtgata agattatcat tttaaacaag tgttccatca caagcctcct
    21121 tttttaaatt gttttcttta gtttcgttct attaaatgtt attaccaata taaaccttgg
    21181 aatagcgtgt aataaatgat tttagaggta ccataagcca cctcctacaa atagaaaccg
    21241 atataaatca atgccttcca cccttagact tccctagttc ctgtctcaag cgaaacattt
    21301 ctttgaaaca ggaataagtt aaccaattca taccaatagc tagcagaata aaaagaaacc
    21361 aaatgcccca taacttgata tctgtcacat ttctcaagac ggtattgaaa aacagaactg
    21421 aaacaactgt ccaagcaagg ctaaaaagag aatagaaggg gatgtaaaac cagtaaaaat
    21481 aataaaaaat tggaaaaaac ttactatttc tgttggcctt ctcaatccag ttatcaaaat
    21541 aaaagtacgg tgctaaaagt aagaatttaa acaaatgttc catcaccgac atcaccctcc
    21601 ttcttttgat agcgttttct attattttat tatatcaaaa aaatccggaa ctgtcattcc
    21661 agattctact tttttatttg cgttttcttg cgatgagatg aatcggtgtt ccctcaaaaa
    21721 caaaggcctt gcggatttga ttttccaaga aacgcaggta agaaaagtgc atgagttctt
    21781 cttcattgac aaagatgaca aaggttggtg gtttggttgc cacttgggtc gcatagaaaa
    21841 tcttgagacg ttttcctttg tctgtcggtg ttgggttgat ggcaatggca tccatgatga
    21901 catcgttcaa gacagctgat ggaatacgtg tattttgact ttcgctgatt tgcttaatca
    21961 tctcaggaag tttgtggaga cgttgcttgg ttaaagctga tacaaagata atcggtgcgt
    22021 aaggcaggta ttggaactgc tcatggatat cttcttccca gtttttcata gtgtggttat
    22081 ctttttcaag cgtatcccac ttgttgacca cgataatcat ccctttacca gcttcatggg
    22141 caaatcctgc gatacgcttg tcgtactcac gaatgccttc ttccgcattg atgaccatca
    22201 agaccacatc tgaacggtca atagcacgca tggcacgcat aacagagtat ttctcagtat
    22261 tttcataaac cttaccagac ttacgcatac cagccgtatc aatcatggta aactcttgac
    22321 catctgtatc tgtaaagtgg gtatcaatgg catcacgagt tgttccagca acaggactag
    22381 caataacacg gtcttctccc aagatagcat tgatcaagct tgattttcca acgttaggac
    22441 gaccaatcaa gctaaactta atgacatctg gattttcttc ttcatattca tttggaaggt
    22501 tttccacaat cgcatctagt acatcccctg taccgatacc atggacagat gagataggca
    22561 gtggttcacc caaaccgagg gcatagaaat catagatatc atttcgcatc tcagggttgt
    22621 ccaccttgtt aactgcgagg ataactggtt tgtgggtctt ataaagctta cgggctacgt
    22681 attcgtctgc atcggtaatt ccttccttac cggacacgac aaagacgata acatctgctt
    22741 cttccatggc aatttctgcc tggtgcttga tttgttccat gaaaggagca tcgacatcat
    22801 caattcctcc tgtatcaatc atgctaaaag aacgattgag ccactcaccc gttgcataaa
    22861 tacggtcacg tgtcactcct tcgacatctt ctacaatgga gattcgctca ccagcgatcc
    22921 gattaaatag ggttgatttc ccaacattgg gacgtcctac aatggcaata gttggtaggg
    22981 ccataatttc tcactttcta caataatttc ttctgttcaa gattttttct agttgagctt
    23041 ggttcagctt gaccaaactg ttctgctagg cgctgactcc agcttgtggt cgcacgcgcc
    23101 ccagcatagt cagcctgaac acggtcataa gcttggattg cctcagttga ctgttcttgg
    23161 tattcttcct caaagacaac attctctagt ggcagtctcg gtttcatatc atgatgttga
    23221 tttggcacac ccagtgccat cccaaagaca gaataggtgt agtcaggtag gttaaagagc
    23281 tctgccactt cttcagactt gtatcgaacc aaaccgataa tcacaccacc atagcccaag
    23341 ctttcagctg ccaacaaggc gttttgtcca gcaagagctg catcgaccga actaatcaag
    23401 agaccttcca caccttgggg ttggaaggtg tcggtatgaa gtcgggctcc cttttctgct
    23461 cggttcaaat ctccgacaaa gagaaggaaa acagcagact ggcgaatggc ttcttgaggt
    23521 accaattcat acaaggcatc tttcttctct tgacttcgta ccacaatcac agagtaggat
    23581 tggaaattct tccaagatga tgccatctgg gctgctgtca aaatctcatt taagtctact
    23641 tggggaattt cttgctcttt aaacctgcgc actgaagtat gagccttcat caatttaatg
    23701 gtttctgtca tcgacggttt actccttcta aacgagtctc ctcagccaaa taacggatgc
    23761 gttccatgac gcgtctggct tcccaggttt cgtcatttcc atgcttccct ttagcgaaat
    23821 gcagctccaa ttcttcaaag ttgaagttgg aggtgaaaaa ggtcggtaaa ttttcctgca
    23881 tccgatattg gagaatgacc tgcaggattt catcacgcac ccaagctgtt gattgctcgg
    23941 caccaatatc atctaaaatc aggacttcag aaagcttaat ctcatccacc aaggtcttga
    24001 cattaccatc accgatagca tttttgacat caatgacaaa gctaggatag tggagaagag
    24061 tggaggaaac accacgtttt tctgataaat catgagctaa ggcagccacc atgaaacttt
    24121 tacccacacc aaagtctcca tacaagtaaa gaccttttcg aatagctgga tattgctcca
    24181 cgaatgctaa taacttttca aaaactggta agcgccccaa atcatccaag tctacttgag
    24241 ccaaactagc ttgcttgaga ctggctggca gattgattaa cttgagacgg ttcttaatag
    24301 ccgcttcttt ttccgctgcg attagctcag gagtttcttc ataagaaaca tccgcatagc
    24361 catgattcat aaccaaaatc ggcttgtagc ctttggcaat ataatccgta tcaccacgga
    24421 gaaacttgtc gcgctcggtg atgtactgat taaacttgga gatactgcga ttcaattcct
    24481 ctggggtcaa ggattcttgc tggataaagg ccgcaacatc agggtccttc atgattttct
    24541 ggaccaaatc ttgataatga aaacggctag gttgacgctt gagtacgtct ccgacacttt
    24601 ccatctaatc tcctcctttt tctaatcgag ctaatagttc ttgtttctta cgttctagtt
    24661 ccagacgagt ttcctcgctg gtttcatttt tataatctgg attgctccac ttgggtacat
    24721 tggacttggc aggactaggg gtactgcttt tttgagcctg attcttctgc ccacgctcac
    24781 ggatgcgcaa gactgcctct tctgccgaat gtatcttttg ataggcatag tcattggcta
    24841 ccttcatggc atatttctca ttgatatttg ccgaatccac cttattaaag gtcaataaaa
    24901 gaatgatatt gatgacttcg tccagcaagc ccaagccagc catctgttgc aagagttctc
    24961 tttctgtttg ggtaatggtt cccttgcgtg tttgcttgat ttctgccaag aactgcaggg
    25021 cagttttact tttggcttct ttgataatgg ttgtttcctt aagactaaaa tcagaggaaa
    25081 ttggtttttg agcaattttt tcacgcatgc gtttggttga aataacctga gaaacagctg
    25141 ttgacttggc caattgatag gtttcaaacc aagtccattt cttctcctcg gcaatagcaa
    25201 agaggtttaa gacatcggac tgctcatccg caaaacgaag tccatctcga gccatcagct
    25261 ggcgaaaatg ttccaagtca aaatcattgg ccactttctt cttgagacca aggtcttctt
    25321 gactgcctag ttctgccaat tctggaaaga cttgattgag tgagacaggt atttcttcac
    25381 catcagcact ttcaactttc aaatcctcca cagctacatc gccaatcttt ttctctaaga
    25441 gtctgcgata aacaggatgc ctcaagaagt cttgactaga tagaggagca tggagggcta
    25501 gctgataaac atcccccttt tgatagaggg tcaagagatt aaaagcagat aagattttca
    25561 atgattttat cagtctatcc atcccaaagt tgagatgatt gaggatactt gaaaaaagat
    25621 attccttcct accattatcc caaaaactga ttgtataaag ataaaggctc agtgcctcct
    25681 gaccgataat cgggaggtag cactgtacca gagatgaggt atcttgcgac acccgattat
    25741 tctttagata agaaaaacgg tcaattggct tcatttatct ttcctttttc tttttagagg
    25801 actgggtgat ttgttggagc aagctctcta actcactgac atccttaaaa ctacgataga
    25861 cactagcaaa acgtacatag gtaatctcgt ccaattcagc caactcctcc atgacgagtg
    25921 aaccaatgtc ctcactttga atttcatttt catttcgacc acggagtttc tgttcgatac
    25981 gattgactac catgttgatt tcatcacttg acacaggacg tttctgggct gagcggataa
    26041 tcccattaaa gattttatct ctggagaatt gttcccgtgt gccatctttt ttaacaacca
    26101 ctaaggttct ttcttctact cgttcgtaag ttgtaaaacg gtgttggcat tcgtcgcact
    26161 cacgtcttct acgaatggtg ttcccttctt ctgcttggcg actatcgata acacttgact
    26221 tggtagcccc acattttgga caacgcatcc tttccctcct tatcgttttc ttttcattat
    26281 accatttttt aagcgattcc caaaacaatt cttctttttg cttgacaagt tttttgtttt
    26341 gttgtattat ttaattaaga caaaagaata agagaaagga gactaagatg tcctggacat
    26401 ttgacaacaa aaaacccatc tatttacaga ttatggagaa aatcaaactt cagattgttt
    26461 cccatacact ggaacccaat caacaacttc caaccgtgag ggagctagct agcgaggcta
    26521 gtgtcaatcc caataccatc caaagagcct tatcagacct tgaacgagaa ggatttgtct
    26581 acagcaagcg aacaactgga cgatttgtga ctaaggataa ggagctaatc gctcagtcac
    26641 gcaaacaatt atcagaagaa gaattggaac acttcgtttc ctccatgacc cattttggct
    26701 atgaaaaaga agaactacca ggcgtagtca gtgattatat taaaggagtt taagcctatg
    26761 tcattactag catttgaaaa tgtatccaaa tcatatggag caacaccagc ccttgaaaat
    26821 gtttctcttg acattccagc tggaaaaatt gtcggccttc ttgggccaaa cggctcagga
    26881 aaaacaaccc tgattaaact aattaatggc ctcttacaac cagatcaagg acgtgtcctc
    26941 atcaacgaca tggacccaag cccagcaacc aaggccgttg tagcttattt gcctgatacg
    27001 acctatctca atgagcaaat gaaggtcaaa gaagccctaa cctacttcaa gaccttctat
    27061 aaagatttca atcttgaacg cgctcatcat ctacttgcag acctgggcat tgatgaaaat
    27121 agtcgtctca agaaactatc aaaaggaaac aaagaaaagg ttcaactgat tttggttatg
    27181 agccgtgatg ctcgtctcta tgttttggat gaacccattg gtggggtgga tccagcagcc
    27241 cgtgcttata tcctcaatac cattatcaac aactactcac caacttctac cgttttgatt
    27301 tctacccact tgatttctga tatcgagcca atcttggatg aaattgtctt cctaaaagac
    27361 ggaaaagtcg tccgtcaagg aaatgtagat gatattcgct acgagtcagg tgaatccatt
    27421 gaccaactct tccgtcagga atttaaggcc taagcaaagg agattattta tgttttggaa
    27481 tttagttcac tacgaattta aaaatgttaa caagtggtat ttagccctct acgcagccgt
    27541 gctagtcctt tctgccctca tcggaataca gacacaaggc tttaaaaatc taccttacca
    27601 agaaagtcag gctactatgc tactttttct agctacagtc tttggtggct tgatgcttac
    27661 acttgcgatt tcaaccattt tcttgattat taaacgcttc aaaggtagtg tctacgaccg
    27721 acaaggctat ctgactttga ccttgccagt ttctgaacac catatcatca cagccaaact
    27781 aatcggtgcc tttatctggt cattgattag caccgctgta ttggctctaa gtgctgttat
    27841 tattctggct ttaacagctc cagaatggat tcctctttct tatgtgatta catttgtaga
    27901 aacacatctc cctcagatct ttcttacagg tatatccttc ctactaaata ccatttcagg
    27961 aatcctatgc atctacctgg ctatttccat tggacagctt ttcaatgaat accgtacagc
    28021 actcgctgtt gcagcctaca ttggtatcca aatcgtcatt ggatttattg aacttttctt
    28081 caatcttagt tctaatttct atgtcaattc actggtagga ctcaatgacc atttctatat
    28141 gggagcaggt atagccattg ttaaagaact catattcata gctatctttt atctcggaac
    28201 ctactacatc ttgagaaata aggttaattt gctttaaata atttttacct agatatgtaa
    28261 catactcata gaacaaaaga gaccaggcaa aaagtcttta aaattagaaa acgcatagta
    28321 tcaggtgtta aaaatccttg atattatgcg ttttttgtga gctgacttat ttcctttcac
    28381 tatatcgcaa aatgaaataa gaacggaacg atgggatttt ggaattcaaa tcaatttata
    28441 agaatgtttt agaagtaata ttatcctatt ccagattcag ttcactatac aattgagttt
    28501 tcaagcaacc tgtttacata atgtgtacat aattaggttc gtgattccac ccttttcacc
    28561 tttaaaaacc tcgctttcgc aaggctcttc tatttataag ataaggcacg tttaaaggtt
    28621 ttccaaatcc ctaaatcatc cgtttgaaga acgagactag catacatgcg tccgataaat
    28681 cctgttgcta ccaccgcaaa aatcactgta atagcaagtg aaatccatgc ttctgctccc
    28741 cccgcatagc cattaatcgt tcgaaacggc ataaagaagg tcgaaataaa gggaatataa
    28801 gaaccaatct tcaagaggag attgtcacca gctgcaccta gagctgtcac tccaaaaaaa
    28861 ccacccataa tcaaaatcat caaaggcgac aaggctttcc ctgagtcctc aggacgagaa
    28921 gccatagatc ctaggaaggc tgccaagact acgtacatga aaagactgat caaaataaag
    28981 agcagggtat tcagtgagat agcatctccc aagtgaacca aaataccaga ctgagccaag
    29041 aatggcaaat ctttaaagag caaaacggca gccagaccac ctacaacata gatcccaata
    29101 tgcgttaaaa tcactagaaa cagagccatc atccgcgcat agaaatagtg acttgccctt
    29161 atgctagaaa aaacgacttc cataattttg gtgccttttt cactggcaac ttcctgagct
    29221 gttacacccg cataggtaat cagaatcata taaagaaaga atcctaaggc acctgctgca
    29281 attgtttgaa taaacttttt attttccttg gcttcatcaa tcttttctgt gaattgaatt
    29341 gtctgcgcta agcgtttttc ctgctcttga gacaaggaag cagttgaacg attaagctga
    29401 ttttgcagtt cattgagtgt acctgtaacc tcaaatttaa ttccattttc aagcaatgtt
    29461 tcgccatgat aaactgcctt tagaacacta tcttcttgat caatggtcaa ataacctttt
    29521 aatttttctt ctttaattgc ttctttggca cttgcttcgt ctttatagtc gaagttaaca
    29581 ccatttacat tcttcagtcc ttctgctaca gatggcactg ttgtcactac tgccacttta
    29641 ttatttttag ccatagaaga accttggata tgcccaattc ctacagagat tcctaaaaag
    29701 aggaacggcg aaatcaccat aaagaagaaa ctccatgact tgacatgtcg aagataggtt
    29761 tccttgatta caacccacat atttctcata cttccactcc tgattctagt ttaaagattt
    29821 catcgatagt tggcgcttgt tggtcaaatg ttgcgatata ttgaccttga gtcaagattg
    29881 ggaagagttc ccttccagcg ctctcatcct ccaaaatcaa tttccaactg ccttgtttgg
    29941 tcaagctcac ctgtttgaca tgaggaagat tttccagttc ttccttgctt cgttcactgg
    30001 aaacaaagag acgcgttttc ccgtattgat tgcggacatc ctgaactggt ccgtgcaaga
    30061 ccacacggcc atctcggatc atcagaatat cgtcacaaag ttcctcaaca ttggtcatga
    30121 catggtcaga aaagataatg gttgctccgc gctctttttc ctgaaaaatg acttgtttga
    30181 gcaattctgt attaactggg tccaatccac taaaaggctc atccaagata atcaggtctg
    30241 gttcatgaat cagagtaata atgagctgaa tcttctgctg atttcctttt gacagactct
    30301 tgattttatc tgtcagcttt cctttcactt ccaacctctt catccattga gggagttttt
    30361 ctttgacttc tttggcatcc atgcctttta gagtcgccaa gtagcgaact tgttcaagaa
    30421 ctgtcaattt aggcatgaga ctgcgttctt caggcagata accaatccga gcataggtct
    30481 cctgacgaat atcctgacca tccagaccga tttctccctg atattctagg aattttaaaa
    30541 tactatggaa aatcgttgtt tttccagcac cattttttcc gactagtccc aaaatacgac
    30601 ctggtcgcgc ttgaaagtca ataccaaaca aaacttgctt ggatccaaaa cttttctcta
    30661 gacttcttac ttctagcatc tttcacctcc gaaatttctt gcactcatta tactcctttt
    30721 tgataacctt tacaacgttt tgtgtccatt tttagaagac tattgctgtg taaaatatgg
    30781 cctggagcac ttttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgtagac
    30841 tgctcaaagt acagctttga ggttgcagat aaaactgacg aagtcagctc aaaacactgt
    30901 tttgaggttg tggatagaac tgacgaagtc agtaactata tctacggcaa ggcgaagctg
    30961 acgtggtttg aagagatttt cgaagagtat tagtgataaa tccattatac agcagcaaac
    31021 ttaatttata ccttccgctc ctcaactgtc tatttttaat cctgaattgt tatttgagta
    31081 actccttttt cctcgtaaag ttttcttcct ctaaaacttc tggaaaaagg ctaatagttt
    31141 cagacaacat ttttataaga aacaagttca tctgtcattt caagaaggag taatccttta
    31201 tctactaatg gacggaacag aattcaaccg cttgtccgat atgttttcta aggattatat
    31261 agtaaaatga aataagaaca ggacaaattg atcaggacag tcaaattgat ttctaacaat
    31321 gttttagaag tagatgtata ctattctagt ttcaatctgc tatatctatt atgcacaccc
    31381 ctataggatc taatgaaaat cacaacaggc tcattcatag atggttacct caggaaacta
    31441 agaaaacgac tacaaaggaa gtcgcattca tcgaaaagtg gattaacaac tatcctaaaa
    31501 aatgcttgaa ctacaagtcc cccagagaag acttctggat gactaacttg aacttgaaat
    31561 ttagcaataa ttaattcacc atctaactat atttagtaat tatttcagaa ctgattaata
    31621 ttaaaattaa ctaacaattc aaaggattca tactagccat aaattacgtc catcagagag
    31681 agactcttac tacttttaga ttttagtctt tctagcttca gaatacatct aaactttagg
    31741 gaaaatgact attcgaaagc gcgaatgcct caaaattatc tcagataagc tattcgaaac
    31801 ttagaatgct tttaaattta tggaattgcg attattcaaa acctagaatg catataacct
    31861 ttagttgaca gacctattct aagtctcgaa gggctattta ctttctattc cttatcaaaa
    31921 aagactcatt ccccctttct cctccaaaat atggtatagt agaaatatac tatctatgag
    31981 gagtttacat gtcacaggat aaacaaatga aagctgtttc tccccttttg cagcgagtta
    32041 tcaatatctc atcgattgtc ggtggggttg gaagtttgat tttctgtatt tgggcttatc
    32101 aggctgggat tttacaatcc aaggaaaccc tctctgcctt tatccagcag gcaggcatct
    32161 ggggtccacc tctctttatc tttttacaga ttttacagac tgtcgtccct atcattccag
    32221 gggccttgac ctcggtggct ggggtcttta tctacgggca catcatcggg actatctaca
    32281 actatatcgg catcgtgatt ggctgtgcca ttatctttta tctagtgcgc ctatacggag
    32341 ctgcctttgt ccagtctgtc gtcagcaagc gcacctacga caagtacatc ggctggctag
    32401 ataagggcaa tcgttttgac cgcttcttta tttttatgat gatttggccc attagcccag
    32461 ctgactttct ctgtatgctg gctgccctga ccaagatgag tttcaagcgc tacatgacca
    32521 tcatcattct gaccaaaccc tttaccctcg tggtttatac ctacggtctg acctatatta
    32581 ttgacttttt ctggcaaatg atttgacacg taaaaaatcc gtttggtttc tcaagcggat
    32641 tttgtgcttt attttgaaac ttcttttgca agaacaaagt tcccaagtgt ggcagaacca
    32701 tttcctgcga ctgctggcgt cacgatatag tcacgcacat ctggtactgg taggtaacca
    32761 ttaagaagag atgtaaattt ctcacggaca cggtccagca tatgttgttg agccatgacc
    32821 cctccaccaa agacaatcac gtctgggcgg aaagtcactg tcgcattaac cgcagcttga
    32881 gcgatatagt aggcttgaac atcccaaaca gggttgttga gttcaatatt ttccccacgt
    32941 acacctgtac gagcttccaa acttggacca gctgcatagc cttccagaca tcccttatgg
    33001 aaaggacaaa cacccttaaa ctctttttca atatccattg ggtgtctagc aacataataa
    33061 tgacccattt cagggtgacc cacaccaccg ataaactcac cacgttggat gacgcctgca
    33121 ccgatacctg taccgattgt gtagtaagcc aagttttcga tacgaccacc agcattgtta
    33181 cgggcaacca cttcaccgta agcagagctg tttacgtctg ttgtgaagta cattggcacg
    33241 ttgagggcgc gacgaagggc accaagcaag tccacatttg cccagtttgg ttttggagtc
    33301 gtcgtgataa agccataagt ttttgagttt ttgtcaatat caatcggccc aaatgaacca
    33361 actgcaagac cagcaaggtt atcgaatttt gagaagaact caatggtttt atcgattgtt
    33421 tcgattggag ttgttgttgg aaattgtgtt ttttctacaa cgttaaagtt ttcatcaccg
    33481 acagcacaga caaactttgt accgcccgct tccaagcttc catataattt tgtcatgata
    33541 aacctcttgt ttttattttc tttattatag catacttcga aagtctaaat gtctctattt
    33601 tttagatttt cctctgtaaa tcttactatc taataaaaac gaacaaacat gtcatttgtt
    33661 cgttttcaca ttagagagga ttgattagat tttcacttcg atcacagcat cccccttcgc
    33721 aactgaacct gttgcgactg gagctactga agcgtagtca gctgtatttg taacgataac
    33781 cattgttgta tcatcaagtc cagctgcagc gattttgttt gagtcaaatg ttccaagaac
    33841 atcgccagct ttcaccttat taccttgagc aacttttgct tcaaaaccgt caccgttcat
    33901 agatacagtg tcaataccaa cgtgaatcaa aacttcagca ccatttcttg ttttcaaacc
    33961 aaaagcgtgc cctgttggaa agacaattga aacttcagca tcagctggtg catagaccac
    34021 gccttggctt ggtttcacag cgataccttg tcccatagct ccacttgaga agactgggtc
    34081 attgacatca gcaagagcga caacatcacc gacgatagga gttacaagtg tttcattttg
    34141 aagagtatca gtctcttcca ctactggtgc ttctactgta ggttctgtaa ctgtttctgc
    34201 ggttgctgtg gcagcttcat cagcaaagac actagctgct tttgttttcc cgtagaaata
    34261 agtgaaagca aaggcggcaa caaaggacat aatttccgca attatataca taggaattga
    34321 accagcctta atagaaagga atccaataaa tccagccgct cccaatgaaa ctgcaataac
    34381 gtgagttaaa cctgctacaa aggcaccaat tgctgaacca gcaagggcgc agaagaatgg
    34441 gaatttgtat ttcaagttta ccccaaagag agcaggttct gtaataccaa ggaaggcaga
    34501 aacagcagcc gaactggaca atccttttgt tttagcattt tttgtcaaga agtagactgc
    34561 aagagtagcc gcaccttgtg ctacgtttgc cattgaagca acaacaaaga tgtagtctcc
    34621 aaatccagta ccgttattat tgtatgcaga caacaattgt gtttcgattg ctgggaatga
    34681 ttggtgaaga cccgtcataa cgattaatga gtaagttcca ccaaatagcc ccataccaaa
    34741 ggcacctgtt gtgttgtaca accatacaat cgcatttgta atcgcatcag acacaaccaa
    34801 cataacagga ccgataactg taaaggtaag gaatcctgta atcatcactg ataaaagcgg
    34861 tgtgaaagtg aagtcaactg cagatggcaa tttcttgtgg aagaattttt ctaaattagc
    34921 taacaaccag actgcaacaa ggactggaat aacctgataa gcatagtttg tttgtgtaac
    34981 atggaaacct aagatgtccc agaaggcttc tttaccaccc aaatctggag tggtcataat
    35041 cataccgatt gccgcaccaa ggaattggtt tgctccaaag cgcttggctg ctgaaatacc
    35101 aaccaaaaca gggaggaaca taaatggagc agcagacatc aattgaatca tagctgagaa
    35161 gcctttgata gcaggataca tatcttcaat tgattgaggt ccaaacaaat ctggtgatgt
    35221 caagaagttc cgtaaagcca tcaagagacc acctgcaact aaggcaggga taataggaac
    35281 aaaaatgtct gacaaaagtt taatcaagtc catcaatgga ttgaactttt tgtctttatt
    35341 agcaatctct ttcaaatcat ctgtcgaaac ttctttcaaa ccagttttct taataatttc
    35401 cgcatatacg aagttaacat caccaggacc aatgataatt tgatattgtc cgttagtgct
    35461 aaaagtcccc ttgacatccg cattattatc cagagctgct tgattcactt ttgcttcgtc
    35521 tttcaatacc aagcgaagac gtgtcgcaca gtgagctgca gctacaagat tatccttacc
    35581 gacagcctca atgacctcgg cagcaacttt actataatcc atagcaaaaa tctccttata
    35641 taacattttg ttcttgtttg aaagcgattt tattcgccct tacgactatt attttatcat
    35701 gttttaaaaa tatgtcaagc gttttgcaga aaaaatattc tatctactta gtgggcaagc
    35761 tttagattga ttgtttttga ctgtttcatc aggaatttct tgaaaaataa gtttgaaacc
    35821 ttggttaaaa agtctttcat ttcattatct ttcacatttt cgtaaaaatt tgattgattt
    35881 cctgtattta ttttatgata atcgtttgac agttttttct cttttttaat ataaaaggct
    35941 tgcatttttt atcgaaaaca gttactatta aaagtgataa gatttttgga ggaatgaatg
    36001 gaatggacaa ctgagcgtcg ttacagactt tatcaagatt ggacgcaaga agaaattcaa
    36061 catataaagg aaaatatggc acaatctcca tggcatactc attaccatgt tgagccaaaa
    36121 acaggacttc tcaacgaccc aaatggcttt tcttactttg atggcaagtg gatcctcttt
    36181 taccagaatt ttccttttgg tgcagcccac ggtttaaaat cttgggcaca gctagaaagt
    36241 gatgatttga ttcactttaa agaaactgga atcaaagttt taccagatac tccattagat
    36301 agccacggtg cctactctgg ttctgccatg caatttggcg ataacttatt cctattttat
    36361 acaggaaatg ttcgcgataa aaactggatc cgtcacccat accagatcgg tgctttgatg
    36421 gacaaggagg gtaagattac aaagattgac aagatcttga ttgaccagcc agcagactct
    36481 actgaccact tccgcgatcc acaaattttt aactttcagg gtcaatatta tgccattgtc
    36541 ggcggacaag acttggagaa aaaaggtttc gttcgtctct acaaggctgt caataacgac
    36601 tacacaaact ggcaagcagt tggcgacctt gactttgcta acgaccgtac tgcctacatg
    36661 atggaatgtc ctaatctggt ctttatagag gaacaacctg tccttctcta ctgtccacaa
    36721 ggattggata agaaagttct agactacgat aatatctttc caaatatgta taagatcggg
    36781 gcttcctttg accctaaaaa tgccaaaatg gtagatgtgt ctcaacttca aaacatggat
    36841 tacggtttcg aagcctatgc aactcaagcc ttcaacgctc ctgatgggcg tgctctagca
    36901 gttagctggc ttggtttgcc agatgtttct tacccatctg accgttttga ccaccaagga
    36961 accttctctt tggtcaagga actcactatc aaagacgaca agctctacca gtatccagtc
    37021 gctgctatta aggaccttcg tgcttctgaa gaagccttct caaactgttc ccaaaccaag
    37081 aacacttacg aacttgaact caacttggaa gctaatagcc agagcgagat tgtcttactt
    37141 gctgataaag aaggtaaggg actttcaatc aactttgacc ttgtaaacgg tcaagtgaca
    37201 gtggatcgta gccatgctgg agaacagtat gcccaagaat ttgggataac tcgttcttgc
    37261 cctatcgaga atcaggctac tactgctaca atcttcatcg ataactctgt ctttgaaatt
    37321 ttcatcaata aaggagaaaa agtattttct ggtcgtgtct tcccacatgc ggaccaaaat
    37381 ggtatcctga tcaaatctgg aaacccaact ggaacttact atgaattaga ttatggtcgc
    37441 aaaactaact gatgtcgcca aacttgcagg cgtcagtcct actaccgttt ctcgggttat
    37501 caataaaaaa gggtatctat ctgagaaaac catccaaaaa gtcaatgaag ccatgcgaga
    37561 attgggctat aaacccaaca acctggctcg tagtctgcaa ggaaaatcag ctaagttaat
    37621 cggcttgatt ttccccaata tttccaatgt tttctatgca gaattgattg ataaattgga
    37681 acaccaactc ttcaaaaatg gttacaagac catcatctgc aacagtgaac atgattctga
    37741 gaaggaacgt gaatacatcg aaatgttgga agccaatcag gtggacggca tcatttctgg
    37801 tagtcacaac ctaggaatcg aagactacaa tcgtgtgaca gcgccgatta tttcctttga
    37861 ccgaaaccta tcgccagaca tccctgtcgt ctcctctgac aactatgctg gtggggttct
    37921 tgctgcccaa accttggtca agacaggtgc ccagtctatc atcatgatta cagggaatga
    37981 caattccaat tcgccaaccg gactgcgcca cgctggtttt gcatccgtac tcccaaaagc
    38041 tcctattatc aatgtttcca gtgacttttc tcccgtcaga aaagaaatgg aaatcaagaa
    38101 tatcttgacc cgggaaaaac cagatgccat ttttgcttcg gatgatttga cagctattct
    38161 ggtcattaaa atcgctcaag aattgggcat ttctgtccca aaagagctca aggtcatcgg
    38221 ctatgatggg acctacttta tcgaaaatta ctaccctcaa ttggctacta tcaagcaacc
    38281 tttggaagag attgcttgtc tcactattga tcttctcttg caaaagattg aaggcaagga
    38341 agtcgccaca actggttact tcttaccagt tacactatta ccaggaaaaa gtatttaaac
    38401 acaagaaaac tcagaccgat tcgtctgagt tttttatgat cttaaatttt cgagatagcg
    38461 ctgggctgtc tctaggttaa aggttttatc tgcgataagc tgctcgacta ggggagcaac
    38521 ttcagattca ctagccccag ctaggagagc tagggatttg gcctgtagtt tcatgtggcc
    38581 ttgctggatg cccgtactta ccaaggcttt gagggctgca aaattttggg caagaccgat
    38641 ggacacgata atctgggcta attctctggc agaaggattt cctagtagat catgactgag
    38701 agctacacgt gggttgaggc cgatagagcc acccttagtc gctacaggca tgggcagggt
    38761 catctcaccg accaattctt ctctttcaag gtccagcgtc cagcaactaa gaccttgata
    38821 acgtccatct cgactggcaa aggcatgggc cccagcttcg atggcacgcc agtcattacc
    38881 agtggcaatc aaaatcgcat caataccatt aaaaattcct ttattatgag tagcagctcg
    38941 gtaaggatca gcctgcgcaa actgactagc caacgcaatt ttctccgcaa tctctcgtcc
    39001 ttgatccttt tggctgctca agtagcgaaa ggcgatgcga cagcttgcag tcaccagaga
    39061 atcggtcgcg tagttggaca ggattcccat gagactctgt ccctgactga gttcttctaa
    39121 gactggtttc aaggcttcca gcatggtgtt gagcatattg gcacccatgg cttcctgggt
    39181 atcgacatga atataaacaa cgagaaagtc tggttcacct tttatctgct cgacatgcag
    39241 gtcacgcgcc ccacctccac gtttaacgat agaaggatag gcttgattgg caagctccaa
    39301 gagctccgct ttcttgctgg caatcttctc ttgcgctagt ttaggattag caacttgata
    39361 aagggatacc tgcccaatca tctggcgctg atggacttgt gcagtaaaac cacctacatg
    39421 cttgatgatt ttgctggcat agctggccgc cgcaaccaca gagggttctt ctgtcacata
    39481 gggaacggtg tattcctgac cgttgacaag tacctccgga accagcgaat aaggcagaga
    39541 aaaagttccc accacattct cactcagctg gtctgccaca gtcacactca tctgttcatc
    39601 ctgctccaga ctagcttgtc tctcaggact aaggagcgcc tgagctttta acagctcgag
    39661 gcgctcttgg tatgattttt tagaaaatcc attccaactt atcttcatta tttttcaacc
    39721 ttgctataac ggcgttggtg gtcgagaatt tcaaccaagg caaaatattg attttcatag
    39781 ccagcaaact gggcagagtt tgtttcatcc aagtctactt cctcaaaaaa gaccttttca
    39841 tagtctgcaa cggataggtc agttcgttgg ttgagcttgt tcaagcggtc tttatccaaa
    39901 taagcttcat atccttcaac caattcacca ctgaagaact cagccacagc tccacttccg
    39961 taactataaa gggcgatttt atccccagct ttcaagctat ctgtattttc caagagagac
    40021 aaaagtccaa ggaaaagtga acctgtgtag atattcccca ccttttgact atagagaata
    40081 gaatggtcaa aatggttttg caagaggtct tttttctctt gaggcaagtt cttatccata
    40141 atttttttca agccttttag cgctaattta ggataaggca agtggaagca aaccgccgca
    40201 aaatcatcta aggtaagctg gtagcgtttt tggtattcaa gccaagtcgt tttcaaacta
    40261 tccaagtatt gttgggtaga atagacacca tttacataag gagttgtcga gtaatttggt
    40321 cgccagaaat ccatgatgtc acgggtctga gctacattgt cattattaaa ggccatcatg
    40381 cgtggatttt gtgtaatcaa catagccaca cttccagcac cctgagttgg ttctcctgga
    40441 gtttcaattc catacttggc aatatcactg gcgatgacca agactttcga ctctggagaa
    40501 ttttccacat gcaatttggc ataatgaagg gcagcagtcg ctccatagca ggcttcttta
    40561 atctcgaaac tacgagcaaa gggctggatg cccagcaagc catgcacaaa gacggccgca
    40621 gccttactct ggtcaattcc tgactcggtc gccacaatga ccatgtcaac ttcttgtctt
    40681 tcttgctcag ttaaaataga gtcactagca ctggccgcca aggtcacgat gtcctcagtt
    40741 aggggcgcaa tactcaattc cttgagtaag agtcctttac ttaatttttc agggtcaatt
    40801 cccctcgctt ctgctaagtc ttgtaatttc aagacatatt gactggtcgc aaaaccaatc
    40861 ttatcaatac cgattgtcat atttacctct gttttatcat tcatgtaaaa aatcgttcta
    40921 tactatttta tcacaaatgg cagtaaaaga gagaaaaaag acttgattca ccaaatcaag
    40981 cctcttattg gtcataattt taaagaatga ttagttgata tagagttcac cgatataagt
    41041 agctttataa gcttcattca cagttatcag ctcctggagg atcaaatttc ctgagtaagt
    41101 ccttcccatc tcatctacaa attcttgata aaactgactg gtcggaattt ctctgacatc
    41161 cttatcaaat gtcttgtcaa gtgttttact aaccttctca gcaatcaatt gatgctcttg
    41221 ccatccactt tgaaactctg agcccgaact agaaaccatg actgggataa acaacaaggt
    41281 ccatagactt acagacaata aggaaaatag tagacttcct gcaaaactag aatcctagtt
    41341 catgattgat aatatcagca atcaaattca ttcgtaatcc gaagcgttta cgatgatttc
    41401 gataggttgt tgaaatcatt ttaaacgttt ttactttggc aaagatgttc tcaaccttgc
    41461 ttctctcctt ggatagcgca tggttacagg ctttatcttc aactgttagc ggcttgagtt
    41521 tgctggattt acgtggagtt tgtacttgag gatatatctt catgagccct tgataaccac
    41581 tgtcagccaa gattttacca gcttgtccga tatttttgcg actcattttg aacaacttca
    41641 tatcatgaca atagttcaca gcgatatcca aagaaacaat tctcccttga cttgtgacaa
    41701 tcgcttgagc cttcatagcg tgaaatttct ttttaccaga atcattcgct aattgttttt
    41761 ttagggcgat tgatttttac ttccgtcgca tcaatcatta ccgtgtcctc agaactgaga
    41821 ggagttcttg aaatcgtaac accactttga acaagagtta cttcaaccca ttggctccga
    41881 cggagtaagt tgctttcgtg gataccaaaa tcagccgcaa tttcttcata agttcgatat
    41941 tctcgcacat atagaaagcg ttgttactat atttatctca tttttcagaa aattctttta
    42001 tttctgtaaa atctacgata ctcgatgtgt ttttatataa tgatacagtc tgagaatcac
    42061 tgttccgcta gctattccaa tagagattac caaagccagc atgacaacca aggtcgcact
    42121 tgccagcgct ttattatagt ctcctgtcac aaaaaaggca gttgtccgat aagaaaggta
    42181 gcccggaacc agcggtgcca aaatggccaa gataaagacc acagcaggag tcttataaag
    42241 aatacttaaa atctggctga cacaagaacc gattatggcg gcaataaagg tagccacaat
    42301 aacattggtc ggttccttga gcaagagata aatcagccag acagccatgc ccaaaatccc
    42361 tccaggtaag agcatagagc gttgcacatt gagtacgatt agaaaagtga taatggcaag
    42421 aagacttgct actgcttgta ataaaaaggt tgttagtgtc atattagttc atcaatacca
    42481 aggcgacaga agttcctgcc cctaaagcaa gggtaatgag cagagattca aacatcttgc
    42541 tcataccaga gtttatgtgg ttggtcataa tatcacgaac cgcattggtc aaggcaatcc
    42601 ctggtacaaa cggcatgacc gcaccagcta taatcaaatc tgctgttgaa ggaaagcctg
    42661 tgtagcgagc ccaaaactgg gcaatcatcc caaagacaaa ggctccagca aaggctgtca
    42721 caaagggaat tcggataaac ttctccacat agagggaaaa ggcaaagcca aataaagtag
    42781 ccactcctgc cccaagtgcg tcgtaaatat ttccactaaa cataattgaa aagaaaggag
    42841 cactaaaggt cgcagccaga gttacctgca acttagtata gggaaggggt tgggcttgca
    42901 aggccgtcaa ttgcttaaag gctgtttcta aatcaatctg ccccccaacc agctgacgag
    42961 aaatctggtt cacatcgcag actttttcaa tgttataaga agaggaggtc acgcgcttca
    43021 tgcgcgaaat attagtattt tcaatagaga aaaagatagc agcaggcatg gcaagaacat
    43081 tgcaatccac aatcccctgc gaatgcgcga tccgaatcat ggtatcttct acacgatgga
    43141 tttctgagcc acttttaagg agaatagtcc ccgctagcat aatcacatcg atgacggcat
    43201 ttaattcttt tgactcttcc atgcttgcct ccttttatca actccctcta ttctatcaca
    43261 aatccggact caaaaaaaat ctttgccaca aaatcatgac aaagattgat tactcatttt
    43321 gattatccat ctgattttaa ggagtagctg aacttgtttt aggtttgtag attgaaatct
    43381 tgactctagt cttattgagg tctacctttt cacctgctct aggactctgt tcaacgactg
    43441 taccttcagc agttccagcg ggagctgtcg acacttctac aacttcaata ttggcttcct
    43501 taatcccaac aatttgaatc aaattattct tagtaaactc caagctggaa ccaatgtagc
    43561 tcggcatggc aacacttgta acttttttag ctactgtcaa gacgatttgg gtaggtttat
    43621 tcacatcata agtcgttccg gcacctggac tttgtttcat aatcgttcct ggttcgcttt
    43681 cgctggactc ttcttcctct atcttaatca aattatctgg aacttttttc tcttttaatt
    43741 ccgcaataac atcagaggat ttccgtccaa tatagttccc taattgaatc gtcgtagctt
    43801 ttttagctac tgtcaagacg atttgagttg ccttgctcaa gtcataggtc gtaccttctg
    43861 gtagactttg cttcatgacc gttccagcct cactctcatt cgactcttct tcctcaattt
    43921 taatcaaatt atctggaact tttttctctt ttaattccgc aatgacatca gaggatttcc
    43981 gaccgacata attactaatt tggaaggatt gtttgcctga tgagacaacc aaattgattt
    44041 tcgttccttc ttttcgacca gttccagcgc caggatctgt acggataatc cgcccttctt
    44101 ccaccttttc actagcctct gtcttctcct caccaatctc aaaattggct tttttgagcg
    44161 ttgccttggc ctctgcaact gtctgacctg ccacatctgg aatggcaatg gttgcaggag
    44221 ttctggatag tatccaaata agagaagctg ccaccaatac aaggctggcc aacaaaatca
    44281 ggtaacgcat cttaaatcta tgttttttcg gtgcttgtgg ttggtaagtt tcctctgtca
    44341 cagcctggct tgggtttttg attgatttgt gttctgtctg cgcttgaacc ttaggaatag
    44401 atgtcaaggt actctgagaa accttcggca aggtcttggt atctgccttg ctcgtttcat
    44461 caaagattaa cttactttca tttctacgat tgtaggacaa gctactagac aagtccacat
    44521 acatctctga aaccgagcgg tagcgattgg tcaacttttt agcagttgcc ttgataataa
    44581 cattttctaa agcctgaggt acagatggat tttctgcaat aacggacggc aggggtttct
    44641 ggaaatgctg gagggcaatg gtcaccgcgc tatccccgtc ataagggata tggcctgtca
    44701 acatctcata gaaaataatc cccatagcat agatatcact ctgcacagtc gccttcgaac
    44761 cacgcgcctg ctctggggac aagtaatgaa ctgagcccaa catcgagtta gtctgggtca
    44821 gacttgtctc tgcaaaggct acagcaatcc caaagtctgt gaccttggca gtcccatctg
    44881 gtgtcaaaag gatattttga ggtttcaagt ccctgtgaac aattcctctg gtatgggcca
    44941 aacgcatggc taggaggatt tgtcccatga tacggactgc ttcttcatta gaaagaggat
    45001 aatgttcctt gatatagcgt ttgaggtcta gtccagcaac atactccatt gcaagatact
    45061 gttgaccgtc ttcctcacca atatctgtta tccgaacgat atgaggatgg tctagatctg
    45121 ccatagctct cgcttcacgc tgaaaacgag ctacagctat cgggtccgtc tggtagttgg
    45181 tcctcagaac cttcactgcc acttcttccc catctaagat taagtctttg gctaggtaga
    45241 catccgccat acctcctcga ccaatctgtt tgacaatccg atagcgtccg gcaaaaatct
    45301 tgccgatttg gatcattctg catcctcctc gttcatagaa acaagggcaa ccgtaatgtt
    45361 gtctaaacct cctgcattgt tagcaaaacg aacaagtgtc tccgttttat ctgctaaagg
    45421 aatatcactg gttacaatat cacgaatctc actgcctgaa atcatgttgg tcaagccgtc
    45481 actattgagc aagagatagt cacctgactc aaggataact gtcccaaaat caggctgaat
    45541 ttcatctttt tgcccaatag actgggtgat aatatttttt tgcggatgag cttctgcctc
    45601 ttctggtgtc aattgaccag ccttgagcaa ctcattgacc aaagaatgat cactcgtcaa
    45661 ctgatggtat tcttctccac gaatcaagcc gatacgcgaa tcaccaatat gagcatagat
    45721 agcctgatta tcaataatag caaggacttc caaagtagtt cccatgcctc tgtaagcttc
    45781 atcctgacca agctggtgaa tcttttgatt ttcaatttct aggtaatggg cgaaccattc
    45841 acgcacttca ttgactgtat cgatctgggt atcaacccaa gctacaccca ggtctgtgac
    45901 cgccatttca ctagcgatat tccctgcgcg atgacctccc atcccatcag ctaaaataat
    45961 catggtacgt ccagctctat tgacatagtg gttgacatag tcttggttat ttgttcgttt
    46021 ctgaccaaca tctgttaata atgaaatttc catgtgtcag ttccttccta atccgatatc
    46081 ttgcgaaatt gactgatgaa gaatccatca cttccataca attcaggtgt aatgaggata
    46141 cagccgtctt tcatgatatc cttacattca tgttctagtt ttacctgctc gaactcggga
    46201 tgactctcta aaaaggcctt aacgacttga aaattctcct ctgagacgat agtgcaggtg
    46261 ctataagtta ttataccacc tttgcctagt atttgacaaa cactacctaa tatttctaac
    46321 tgaatttcct gcaaggacgc gaaatctgcc gtttctttat tgtatttgat atctggtttt
    46381 cggcgcaaaa gaccgattcc tgaacaagga gcatccacca aaatcttatc aaaggaatcc
    46441 tggtcaaaaa actcatgcac ctttctggca tccaattttt gagtttgaac ccgatctgca
    46501 actcccagac gttgggcatt ttcttgaatt aaatccaact tgtggtcgta caagtccaga
    46561 gcagtaacct gacctgtcgt aagataagag gctatatggg ctgttttccc acctggagcc
    46621 gcacaggcat caagcactcg ctcatcacct tgtaaatcaa gcgtcggagc aaccagctga
    46681 ctggactcgt cttggatggt aatggctcca tccgcaaaca aattatgccc tgcaaaatgc
    46741 ccttgctcct taacgagacc agtggttgct aaaagggaat tattcgcctc caacaaggct
    46801 tggatttcct cttttcgact taggtctgtt acacgaatac tggctttgtt tcgcactaac
    46861 aggctttcaa agatggcttt tgctctctcc tctccgtatt cttccttgag tttggcaact
    46921 agccaaactg ggagagaata ggcaatggag tcacgcttgt tttttcgctt gatgctagca
    46981 atatctggcc agccttcacg caagatacgg cgaaggacag cgttgaccaa tttttcactg
    47041 ccttttttac ggagtttggc caattccact gcttcattaa ccacagcatg atctggaatc
    47101 ttgtccaaat agcggagttg gtaggcactc atgagaagaa ggacatagag ccagctgtct
    47161 aactggtctc tgtcttcgat aaagtgggat aggtaccatt ccagagtcag tctacgggct
    47221 accgttccat agaccagctc ggtcactaag gccttgtctg ctgccaaaag ttgacttccc
    47281 tttagatgct tatttaaggc gatatttgaa tatgcttggt tcacaaaaac atcctctagc
    47341 actgctagag ctaaacttct agccgtttct actttagtca ccaaatcgtt ctcctacagt
    47401 caatgtacgt ccaactccgt tgaggaagga agcaatgtcc atcttaggct taccagctgg
    47461 ctgcacttgt ttgagggata gagccccttc agccgttgcg acaatcaatt ctttcttgcc
    47521 gatagagaga atctcacctg gatttccctg accttctact ggtagggctt cataaatctt
    47581 aaagcggtcg cccttaagga aagtatgggc aacaggccag gggttcattc cacgaatttg
    47641 gttaaagagt tgacgattgg ttttgttcca gtccagtttt tcttcctctg gctttatatt
    47701 tggagagaag gtaacctgac tcgtatcctg cggttcaggt ttgatatcac cagcaatata
    47761 ggcaggcaga gtgtccaaaa gcaaatcacg accaactagc gccaattttt caaacaaggc
    47821 gccaacattg tcctcatctg tgatcggaat gctgcgacga gaaatcatat ctcctgcatc
    47881 catttcctta accatttcca tgatggtcac accagcttcc tcatcccctt gaatcaaggc
    47941 ataatggata ggcgcaccac cacggtgtct aggaaggagg gaggcatgaa cgttgacagc
    48001 aaagtccatg ctatcaagga gtttgcttgg gagaaactgc ccaaaagcag cagtcacaat
    48061 tccatctgct cctagcttta taagttcttc catctctgga cttccagata atttttcagg
    48121 ttggtagata gatagtcctg cttccttggc agcctgcttg actggggttt cttggataac
    48181 ttttttacga ccaacagcac ggtctggctg ggtcacaacg gctagaattt cgtaacggtc
    48241 atctgtcaaa agtcctttta agactgttgc tgaaaagtcg ggggtcccca taaagattag
    48301 ttttgtcata tcttctcctt cttataaaaa ttgctgcggc tcatggtcaa tgctgagacg
    48361 gagctcacta ttttcccgtt cttgagtcaa ggccaagacc tggttgaggg tcagccccag
    48421 ctcatcttct aaacgatatt taattaaaat ctggtaatga tagagattgt gggtacgggc
    48481 aatcggtttt ggcgttggcc ccagaatggg actggtctct gacaagcctg accgcaaaat
    48541 gttcatgact tcataggcac gtttgaaaac ctcttcttct ttcttgtgag aaagggtaat
    48601 accaatcgtg aaatagtaag gtggatagca gagttgtcgt ctgattccca tttcataggc
    48661 ataaaagcct tcgtaatctt gatccttggc aaatcgaata gcatagtgct gcgaattgta
    48721 ggactgtatc aagacttgac ctgctttttc agcccgacct gctcgacctg ccacctgagt
    48781 caagagctgg aaggttctct cagaagaacg gaaatcaggc agattcaagg ccgtatccgc
    48841 atttagaact ccgactaggg taacattggg aaaatccaaa ccctttgcaa tcatctgagt
    48901 accaagtaaa atatccgctt cccctcgccc aaactggtca agcaaggctt ggtgactacc
    48961 tttctttcga gtcgtatcca catccatcct cagaatgcga gcttggggaa agagttctgc
    49021 tagctcatca taagccttct gagttcccgt cccatagtaa cgaatactgt ggctcttaca
    49081 gttaggacag acctgaggaa tatccttcga gaaaccacaa taatggcagt tcatagtctt
    49141 ggtatccata tgcaaggtca gagaaatatc gcagttggga caagtatcca ccgtcccaca
    49201 ctcccgacac atgacaaagc tagaataacc acgacgattg agcatgagaa ccacctgctc
    49261 ttttttaacc agacggtctt ggatagcctc tagcaaagga ggcgtaaagt ttgacgtctc
    49321 attttgtccg atatagtctc gaaagtcaat cacttgaacc tcagggattg tagccaaagg
    49381 attggcacgt tgggttagac gtaagtgttg atagacgcct ttgccagcac gcgcccggct
    49441 ttctaagctc ggcgttgcag atccaagtac cagagttgct tgattatact gagcccgtaa
    49501 aatagctacc tctctggcat ggtaacgggg attgctgtcc tgcttataag ccacttcatg
    49561 ctcttcatca ataatcatga cacccagatt tttcagagga gcaaagatag cagatctggc
    49621 accaacaaca acttgggcat cgccacgctc caccttgcgc cattcatcat acttttcacc
    49681 attggataat cctgagtgaa gaatggctac cttgtcccca aaacgtgcta taaaacgctc
    49741 ggtcatctga ggagtcaagg aaatctcagg taccagcaaa atagctgtct tgcccttatc
    49801 cagggtacct tggataatct gcaagtaaac ctcggtcttc ccacttcctg taatcccttg
    49861 aagtagaaag ggaggttgag aactgccaat agaactcaca accgcatcac gcgcctgtct
    49921 ttgttctgga tttaactcca aaggtctact tgcttcaatt ccttcaaaat aagcagccga
    49981 gcgttgaact tccttttgga ctatggtaac agcaccttga tccacaaaga agttgacttg
    50041 ctctcgcgag taggactcta acaagctagc caaggaagcg ctctctggat gagacagcag
    50101 ataatctctc agttccaact ttttcttggc acgtgtagaa atctcaacac cttctaattg
    50161 aacatggtca acctcatacc aagactgggt cttgaccttc ttttgatcga ctgcctgata
    50221 ttccagacca agcaggcctt ttctagtcaa acgcatcatt tcagcttgct tacctaaatc
    50281 cagagaagaa aaggcaagtg aatcttctga accaaacagg cgtactcgtt cttcctgact
    50341 caagccttcc agaggatata gaatcttgtc atagctagaa ttcagaaatc ccggaagcat
    50401 ggccttgagg atggaaattt tgtaggagaa gacggacttg cgtaactcct cagcaagcca
    50461 gagttgttct tgcgtgagaa cgggagaaaa atccagtacc tcggcaatat cttttaaatc
    50521 ttgctccatc tcttcttcgt ctgattgaga ctccaaacca agaacaatcc cttgaatcag
    50581 gcgattgccc ttaccaaaag gcacatgaac ccgcatccca acttccagca ttccctcaaa
    50641 ttcctccgga atcctgtaac tatagggctg gtccgtctgc atcaagggca catctacgat
    50701 aatcttagct agggccatct tctcacctcc tccttgtcag tacattcttg caatagaaaa
    50761 aataagattg agtcccccca accttaaatt ttttcaccat cttctttttc tttagcaatt
    50821 tgctctttga ttttcttttc ttcttcttct ttgcggcgtt tttcttcttc gatacggcga
    50881 cgcactgctt cacgttttcc ttctggatct gggtgaattg taacgtttcc tgattcgatt
    50941 tcttctaaag cgcgaagagt tgatttttca gacttgaaac cttgagttgc tggggcacct
    51001 gcttccaatt cgtgggcacg ttttgcttcc aagattacga gtgaatattt tgaagtaacc
    51061 ttgtcgagca aggtatcaat agagggtttt aacatcattt gcttgtacct attttctaaa
    51121 ttttatcggg tagttggaga ttttggtaac atctcctgat agtgaccaat gacacgatcc
    51181 acacaaaagt gttctgcttc aatcacacat ttgacacgtt cagcagctag ggatacctga
    51241 tcgttgacaa tcgcataatc atactcacgc atgagggcaa tttcttcctt ggccttttcg
    51301 attcgttggg caaccacttc tgcactatct gttccacgac ctaccaagcg ttcttgcaat
    51361 tcatccaaat ctggtggtgt caggaagata aagacagcat ctggaacctt tttcttgacc
    51421 tgaagagcac cctgaacttc aatttcaagg aaaacatcga ttcccttgtc caaggtttca
    51481 ttgacataag tcagaggagt tccatagtag ttgccgacat attctgcgta ttccaacatc
    51541 tgtccttgac gaatcagctc ttcaaattct tcacgagtac ggaagaaata gtcgacaccg
    51601 tccacttctc caggacgttg tgcgcgtgtc gtcatcgata cagagtattg aaattggttt
    51661 tcagaactct caaaaatctc tcttctaacc gttccttttc caacccctga aggaccagaa
    51721 aaaacgatta gtaagcctcg gtctgccatt gtgtctcctt ttagtcaatc tgtgaaataa
    51781 catttctcta gaataatggc aaaaagccag attatccttt acagtctttc tatctagtgt
    51841 aacaaaaaag cagtaatttt tcaactgctc tttcttattt atttagcata atctactgca
    51901 cgaagctcgc gaatcacggt taccttgata tttcctggat aatcgagatt gttttcaatt
    51961 ttcttacgaa ctttgtgagc caagattgtg actttgtcgt ccttgatttt tcctggattg
    52021 accatgatac gaatttcacg tcctgcttga agggcaaagc tagtttgcac tccttcaaag
    52081 ccgttagcaa tttcttccaa atcatggaga cgcttgatgt agctttcaag agactcacta
    52141 cgagcacctg gacgggctgc gctcaaggca tctgctgcag cgacgataac tgctatcacg
    52201 ctctcagctt caacatctcc gtggtgacta gcaatcgtat tcaccacaac tgggggttcc
    52261 ttgtacttac gggccaattc cataccgatt tcaacgtggc taccttcaac ctcatggtca
    52321 atggctttcc cgatatcgtg aaggaatcca gcacgacggg caagagccgc attttcacca
    52381 agttcgctcg ccatgatacc agccaactta gcaacctcaa tcgaatggcg caaaacattt
    52441 tgtccatatg aagtacggaa ctgcaaacgt cccataatct tcattaagtc tggatgaagg
    52501 tttggcgcac caatctcata ggctgctgcc tcaccgtatt cacggatctt attgtcaatc
    52561 tcttgacggt ttttctcaac caactcttcg atacgagctg ggtggatacg accatccttg
    52621 agcaacattt ccatagtcat acgggcaatc tcacgacgaa tcgggtcaaa tcctgacaag
    52681 gtcaccactt ctggcgtatc gtcgataatc acatcaacac ctgtcaaact ttcaaaggta
    52741 cgaatgttac gaccttcacg accaataatg cgtcccttca tagtatcgtc tggtagatga
    52801 accgttgagt ttgttgactc cgctacatat tcaccagcga tacgttgcat agcttgaacc
    52861 aagatgtcct tggccatttt atcagaacgt tccttgacct cttgctcagc ttcgcgaata
    52921 cggctggcaa tctccttggt caaattttcc tctgtctgag ccaagataat atctcgtgct
    52981 tctgcctgag acagggcacc aatacgctct aactctgctt cttttcgtct ttcgacttcc
    53041 tctaattgct cttcacgcgc atcaaggttt ttcgctctat cagaaatact ttgttctttt
    53101 tgttcaagtg tttgttcttt actcgtcaaa ttgtcgtcct tacggtcgag gctagtagct
    53161 ctctcggtca aacgactttc tatttgtttg agttcttgac gttctgattt gaattcagcg
    53221 tccacttctt cacggtattt tctggcttct tctttggcct ccaatagtgc ttctttttta
    53281 agagacttgc tttcacgttt ggcttcatta accagtaaat ccgcttcacg ttcagcttgt
    53341 ccacgtaaat tagttgcttc ttgttcagca tttaaaagca tcaactccgc agcttcctga
    53401 gatgatttca tcttagctga gatgctgaca tatccaatga ctaaaccaat gatgacggca
    53461 aaaacagcaa tcgcaagcga catgatttcc atgtttttac ctcattttat tgttattctg
    53521 aatgacatac attcttttac attctaccat aaaaaagtga ttttcacaaa cctaaaatag
    53581 aatatgtttt ggggaaatta gcgtgaattt taagattaca cttcttcgga tcccttcaaa
    53641 cttttgaata catcatcaat aaatatatct gctaatctct tcttgaaaga atcattattt
    53701 aatagagcac caaataaatc ttgactctga gagtatcctt ctataagagc attgtcaatc
    53761 tcttcttcaa aagcaaaaac gaagtcttct ctggagttga cacgagcaga ttgctttagt
    53821 cttggattct ttttcatcaa ttcacgaatg gataccgctc cacttagacc gacttgggga
    53881 tcaatatcca aatccaactg ttcgttaatt tcatctaaga tttcagataa acgcttctcc
    53941 tggtcagtcg taacacctcc agtacttggc ttggtaagta ttaactctgg atgatattcc
    54001 aattcagaaa ctgacctgaa ggaacctgtt tgcttatgtt tcatatagtc cactacgatc
    54061 ttatctgcta ttgtaaaatc atctcctcca atgcgaacat caatcatctt gacaagactt
    54121 tgcagataat tataacgttc gtgtagaact tcattttgat aagcagttgc ctgaatcaag
    54181 aaagtataca ttctaagaaa acctcgaata acctttcgaa tagaaagttg ttctttctca
    54241 tcaaaccgtc taactctatc ataaccttga tttaacagag aaaccatctt ttgcttttct
    54301 ctgctgtttc tcttttcttg gtataagaat tgattaaact catgaataac atcactgtcc
    54361 aagataccat actcatcaat tttccgatcc aaggtcaaga catcactagg tgtgactgta
    54421 tctgctaaaa tagtctcacg gtagtaggga gaaaaagctg aacgaatatc gtcataagta
    54481 tttttaaaat caagaataaa ggtcctctta ttgtagcctc tatagatacg attcaaacga
    54541 gacaatgttt gcaccgcagc aacacttcgc aactttttat ctacatacat agcaaccagt
    54601 ttgggttggt caaaccctgt ctgatactta tttgccacaa tcagaatttg gtagtcttcc
    54661 gtatcaaaat gatctttcaa ataatcttcc ttgacctgat tcatttgcga ctcagtatat
    54721 tcactacctt gataatcaac cttgccagaa aaggcaatca gggttccaat actggtaatg
    54781 ctgtggtctt tgaagtactt ttgaaaggct aattgatact taactgctgc ctcacgacca
    54841 gaggtcacaa tcatagcctt accttgacca cccaattcag ccataatatc atgactgata
    54901 aagtgatcca tgataatttc aaccttttga ttgatatttt catcagataa ttctacaaac
    54961 tttgcaatct tacgcttggc aagagtcgtt tttagctcag gatcttcttc gactgcttta
    55021 ttgagcttgt aataggtctt ataagtcgta tagttatcta aaacatctag aataaaacct
    55081 tcctcaatag cttgcttcat actataaaca tcaaaaggag ctttagaacc atctgcttgt
    55141 gttgtaccaa atagctgtag agttgtcgcc ttgggagttg cagtgaaggc aatgattgag
    55201 acattgtcct gcttacctgt ccgagcaatc tcctgctcga tagcgtccgc aacacttact
    55261 tcttgaatct catcgatagt tccatcttct gtatctgttt ctgtcaagac ttgactaacc
    55321 gaactcatat aggatcctgt cgttgaactg tgagcttcat caatcaggat ggcaaatttc
    55381 tttttcgcag tgttccctac agacatccag ttagattggt tgatttgggc aaacttatga
    55441 atcgtcgtag ctatgatttt tgtatttcct gcaatcgcat ccgctaagtc actggaggtt
    55501 tctttgtcgc ccattacctt gaccactcca ggcttgtggg aaatttcctt gaccgcttct
    55561 tgtaactgac gatcaactac gatacggtct gtaacgatta atacagtatc cacaatattt
    55621 tgattttgtt catcatggag cgataccaaa ctatgagcca accatgctat ggtattggtt
    55681 ttacctgaac cagctgagtg ctgaatcaga taattactgt ctgtatggtt gactttcatg
    55741 tcttctagga gacggctaac tgctcttcgc tgatggtatc tcgggaaaat cagggtcttc
    55801 tttttagaat tatgcttatc catctcatcc atctcaaaaa agataaaact atctattaac
    55861 tggagaatac tatccttggt caagacatca agccacaagt agtctgtatc gacaccatca
    55921 gggttgtgag ggttgccact tcccatctca ataccttccc ctttccccac attaaaaggt
    55981 agaaagtatg tttcttgtcc tttcaattgc gtcgtcatat agacttctag ggtatccact
    56041 gcaaaggaag ccaagactcc ctgttcaaaa cggaaaagac gattcttagg attgcgtccc
    56101 ttgagctgcc tgatagcatc ctgaacagac tgaccactgg gattaaactt aagttcgata
    56161 gcaaatagtg ctaatccatt gataaagata acaaggtcaa tgcggtcgct ctcctcgtaa
    56221 accacttctt ccataataga tagacagttg acttggtatt gttgaacagc cttttcatta
    56281 aaactagtcg caggtttacg ataaagaaga cgaagttgtt tattttcaat aaaaactcct
    56341 tctttcaagg cgaataaaaa gccacccttg acgatttctt tattaatcag attgacgatt
    56401 gtctccttac tcagtttttt aaggagatag tccatggtct cctcttgggt ctccatcaga
    56461 aaatcccaca ggagttccac atccatggct aatctaggat cgtagcaagt agcgtcccgc
    56521 tgaatatagt cattcttatc tctcaaatct ttgataatcc actgctggaa atcatagcgc
    56581 tccttcaagc ccaaatttgc catagcttct cactttcttt ttctataatt caattaaaaa
    56641 tttcgttata attacaaatt taaagtttac aatgaatttc ttaaaatcta aaaatgataa
    56701 aactgatatt ttattgtact tcaatattat cttttttatc tttctgacgt ttatctgcaa
    56761 gtgaatcttc gtattcattt ttagcaatac ccaatttctt tgcatttgta atcacagaaa
    56821 taaaggcctc aagagactct gctgttagat atatctcttt acttttttca ttaaaagtaa
    56881 aaggtgtttg aaaaaactgt gctgataatt tattcgctct ctttacacat ttccattcat
    56941 agctcgatgc ttcatcatta tattttgcaa gcaaattaat caatttacga tgacttttta
    57001 atttagcttt tattttttca gattcttcat cagatacttt cactttaaaa tccgtcgata
    57061 atttaaaatt atgagataaa aatttcttat aattctcttc agccgtgatt attttcgact
    57121 catttaaacc aaacataatt tcataatcct gaacatcaaa gatatattgt atagtttcat
    57181 tgttttcagt tttttcagca taacttatga taaacggaag acttcttccc tcatcttttt
    57241 ctatatcaac tattttaact tttccagaag tcaaagtagc aatgaatcta gtttttaatt
    57301 tcgcaactcg aattgatttc aaaaaatatt tgtactgtac accatcaatt tcttcacaaa
    57361 ctagatacaa tcgtatatct tcaaagttct ttagaggagg taaatctgtt tctaattgag
    57421 atgagactaa ttgtattcta tctatttcag actggagact ctcatcaatc tttctataaa
    57481 atggaacttc cgtattattc ccattcgttt caacattttg taatgactca attgattctt
    57541 caaatttttc ctttaaagtt aaagttgatt cattagaatt ttgattatta gcaaattgaa
    57601 tattacctat ataattacta gcttcatctg agataacttt tcgaaaattt ttcaatttcc
    57661 caagtgactt acctcgtcca acctgccaac caattgcata tatttctacc attctactct
    57721 cctatttcat catttaatac ttcttgatca aaaaaaaaca aatgttcttg ccattgtacc
    57781 agtatttcct agagtacaaa tccttttcac accagaaaat gcagccgagt cttttcgaaa
    57841 gaaaaatata ttgtagttat cttttgtgac tagtaaattg acaccaaaaa taggtaatat
    57901 caagtttgga aaaatatcat tgctaagcat taataacaca aaaaagaaaa caataattat
    57961 aattgctact agagcactaa ctccattcat aaatttcaaa actaaagagg gtacaatggt
    58021 tgacgataca aaggatatga atcctggatt tatttttggt ccgtcttgaa tatcaatcac
    58081 tttgccttga gaattatttt tcaacgtgac cttaaataca ttaaaattta aaacaatatt
    58141 tttaacaata ttttcttcac tcctccgtcc gtttatatat ccacgtatac tgtaaattga
    58201 tattagcatt atagaaagta atactgataa cataagaaaa tgccacaagt tcctacttaa
    58261 ataacaaggt aacgactcag tctcttttaa taaaaaatga tgaatatcta ctaatgaaaa
    58321 ataaatcaat aaaaatgctg gaaaaaatgc ggtaaaaaag taagctaaac gaaattttaa
    58381 atcagttcca aatagcaatc ctacaccctc ctcttccctg tcacataatc ataaataaga
    58441 gtttgtcgtt gtttgttaat atttttaatt tgctgattct tgatttgtat aaggttatca
    58501 atttgagcgg tgttttcatc caaaagatta gcaatttttt gttgctcaac aaggcttgat
    58561 ggaaaagtaa ttttcatatt ttttatatat tcccaacttg ctctaggcat tttactacca
    58621 taagtagaag tattaacttc ttcaataaaa ctatcacttt gaatagcata gtagagaaaa
    58681 ttcatgtcta attctgaaga ttgaaacaca agaaattctg aactagctgt tgaagggaag
    58741 gtagctcgcc aatattttct caaatatggt ctcagctttc caaataaaac atctccaatt
    58801 tcgactacaa tattctcact cttatcaact tgtataccag tttcaacaaa tttcccagtt
    58861 tgactttcta tattttctaa tcctatgtaa ggtatagaag agtctgttat tcttttttca
    58921 cttcgagtag ttactaaata tcttatttta gaaatctccc atccttcagg cacctgtcca
    58981 atccagtcga ttcctgaatc cttcataggg acgtttttat ccagtccttt tgtgactgtt
    59041 tcataaatca agctagcgcg gtagtctttg agtttttgaa tctgctcttc caatagggct
    59101 ttaaccttat ctaactgagc tgttttcttg tctaggaaat cagcgatctt ttgttgttca
    59161 ttttttgagg gaaaggtaaa agtaaattca tcaaatacat tttgatataa atgtaaaata
    59221 gtgctagctc ctgaatttgt atagttaaac cacatccaaa attcatctga tagcaaaacc
    59281 aaatataaaa attttctatc aatctcatca acagtttgga ttcttaatac accactattt
    59341 aacgaagcct tatcatcaag ccctgaaata atagctactt tacccaccgt accatctttc
    59401 gtaattagca aatcgccatt ttcaacctga atctgtgaag cttctgacca acgtttttca
    59461 tcaatatgta cagctgtttc aaaattaatc gctccattgt aaaagtcagt tcctgtaatt
    59521 aaatatgggc cttcctcttt atattcagct gatgttaatc cttgccaacc aattctacca
    59581 ttaagctgtg ttgtgaattt tattttagaa atcacccact cttctggtat ctgtccaatc
    59641 cagtctatgc cactctcttt catcctagtc atgtttgagt tcctccaaga gagtctgtag
    59701 ttctgcttcc aaggcataga actcagctaa gagcttttct gcactttctg gttcttgata
    59761 ttgatagaaa tagcgggtaa aaggaatttc tgctccatag cctttttcct catcaaacca
    59821 gtagtgggcg tcaggtacat ggggatagac ctcacgcgca aagtaggttt ccacatcctc
    59881 tgtcagctta acgatttcac tgtccttggt tgtcttatcg tagacaattc catcggcaat
    59941 ctcatttgcc ttgtctttct tcttggttcg gataacctct gctgtcttat ccatttcact
    60001 catagctaag gctagcgcat tgatattagc aggcgtaagc ttaaactctc ccagcaagtc
    60061 cttgatgact tggacaaagt tctcaaagtc aggataggtc ttgtcagaac ttcccttagc
    60121 aagagctgtc aggatagctt cttgcttgat cttgccagct acaaagtcct gtaatttttt
    60181 ctcatccttg gctgaacgtg gttccatctc cagcaattct tggtacttgt attcatcaaa
    60241 tagtttagct aggaaaggaa cacttttcgc tttctcaatt gtttcttcac ttatctggcc
    60301 acgacgttgc agaggttgca taactgtaaa ctctcgatag agaaactctt gattctcaaa
    60361 gatttttaca tggtcatttt cttgaaaatc atcgtaccag cgaaggatct gacggatgtt
    60421 atcttgggac aactcacggc gtttttgacc tagagattta cgtagaggaa taaactcctc
    60481 cgtagcatcg ataaactgaa ccttgttctg gcgctcagga gacttgtttt tattataaat
    60541 ccagatataa atcccaattc ctgtgttata gaaaaattga cctggaaggg cgactatagc
    60601 ttctagcaag tcattctcta ggatataacg gcgaatctga ctttctcccg atgacgtccc
    60661 acctgaaaag aggggagacc catttgaaat gatggctgca cggccatttt cttctaattt
    60721 tgtaagagca tgaagatgga agagtagttg agcatctcca gttcctggag tcgcaacaaa
    60781 acgaccttga cgaccttctg ttttgtcaaa gagttgatga tctttcttaa ctgcatcctc
    60841 aactccatca tccgcatcct taccacccca agcttggccg aagggagggt tagcgatgac
    60901 aaagctcatt ttagtatctg gaaaaggatc tggatctttt aaggtatcca ccttcacaaa
    60961 atagtcagag tcttcctgac gaattagcat atctgcacga ccaatcccaa aggtttcagg
    61021 caaaacttcc tgaccaaaga gtcgggcagt ggctcctgta ttcaactgac ggatatagct
    61081 tttagctgta gccagcattc ccccagttcc agccgccatg tctagtattt tcaactcttt
    61141 tttatcaaca aaaagttctt cgtctgcctc aatcaagagg aggttgacca tcagagcgat
    61201 aacctcacga ggggtatagt gagaccccgc ttcctcattt tcagaaaatc ggcggatgat
    61261 atcctcaaac atgtatccca tacgcataga gtcgactgaa cttggagaca aatcaatttg
    61321 agagaacttt ttaataaccg tgaaaaggcg accactctgg gccagggtac ggacttgctc
    61381 tttaaatttt aggttttcaa tgatgtcctt gacacgacaa gaatagccat ccagataggc
    61441 tataaaattc tcctcgattg catttggatc gttttgaaga ttttccaacg taaaaggact
    61501 aacattgtag taacgatagc ctgaaagttt ctccaacact ttctcaggtg tattgggatt
    61561 tgctttgtat tgtgctacca cctgatcctt ggttggcagt aaggcagctt ctaaacgagt
    61621 caggacaaac attggaataa tgacatcgcg atacttatct gctcgataag ctcctctaag
    61681 agtgttagcg atagaccaaa ccgtattgac atcattagag atttggatat catttgcttg
    61741 gaatagtggt aatttttctt tgaaactaga catttacttc ccctgttttt attattaaca
    61801 attctcttca ttataccaca aaatacaagt gataaagcgg attcaaggga aaaaatcgaa
    61861 gtttatatac taaatttctt tactgagttt ttgtcttttg tattagggat tctgtcattt
    61921 tctaaaaaac tttatcttaa acttactcat aaaaatttaa aaaataaaaa gcccaccttt
    61981 cagtagactt agtagtgatc tttgaaggac aaaaaagcga tgctatctcc atccatcata
    62041 taaatcaagc gattttctgc atcaatacgc cgtgaccagg ctccttggta gtcatacttg
    62101 agtggttctg gttttcctat tcctgtaaat gaatcacttt gaatatcctt aattagttta
    62161 ttgattcttt ttagtgtttt cttatcctga gtttgccagt agcaataatc tgcccacgca
    62221 tcttctgtaa acttgagcag cattcctcac tcctcaataa catggacttg agtgcttcca
    62281 gcacggactt gagccattcc tcgcaaaacc ttgtctgata actccttatt ttgaacgatt
    62341 ctcagggttt cctgaatact gtcccattcg ctctttgaaa gaactacaat gtcctcatct
    62401 ggatttttat taaccaccgt taaaggctca aattcatcat tgaccttctt catgtagtct
    62461 tttaaatgat ttcggaatgt tgagtaaaga actgcttcca taaccatacc tcgttttacc
    62521 tcttttccac tattatacac gaaaagaaag aaattgtcag aaacttgtac aagattttct
    62581 tttctatcta tttattcgta aaaaatctca aaaagcctac ctttcagtag acttagtttg
    62641 tttctattct tattggcact cttccaaaat tctgttctgc tatacttgga tttcctagtt
    62701 ggtaaatctg gtctgccttt tgggtcatag tatcccaagg ctctttgcca attcgactga
    62761 ctagattgac ctgacctttc aaagacttga gatgttgcct gcctttttca gtaaatccaa
    62821 ggacatgaat ggcttctgac aagtcacttt ctctagcttg caccaaaata taggtcaaaa
    62881 gacgtctgac acgcgccttg gtgtaacgct tggtcgcaac caccttaacc aagtcttcca
    62941 cagactgggc tggtttaata gcctctttaa tgcgcacagc catttcttga ttaacctgat
    63001 agatggtggt taggtctgaa ttggacaaga tttgatagcg gagcatagga aaatagtcat
    63061 cccagctcac cttactggcc tgctcaaaga gggcaacaga tggcataaag cgttctaaga
    63121 aatcttgatc tgactggtgc tgacggaggg ccgtcgccga ggcaaagtcc acatccttgt
    63181 ccacagaatg gtaaccagcc ccctgacgct gaatcggatg gagcttgata tttcgtccag
    63241 caaccgcctt ggcataagca agagcaagga catgattggg tgtattgcct gaaaaatcaa
    63301 gatctgcaaa ttctttccac atggcttggg ttttctgggg ataggaaaga gaatcaggca
    63361 gtttttccac aaatttctcc atctcagcct cctgctctgt gtataagtca gcgatttttt
    63421 gataatccag aacttcctcc gtcccaaatg ctagagtatc aatgcccaac cgagccaaga
    63481 tatccacagc tccttgaccg aagaaatctg ctgcctgaac actgactaaa aagggcaatt
    63541 ctactaccag atctgctcca ttttccagcg ccatctgggc ccgtatccac ttatctataa
    63601 tcgctggttc tccacgctgc atgaaatttc cagacatagc cacgactttc agtccttcag
    63661 cctgttccag caggtatttg tgtccattat gaaaaggatt aaactccgca ataatacccg
    63721 tgatggtcat gctaatctcc tacttctgcg cgacaaaaaa ccaacgggca cttgtctctg
    63781 tcggctcctt gtcctcaaaa tccgcatata gtttgaagga cttgaaaccg gcctgttcca
    63841 gcaaaatatc ataggtcaga acctcataag tccgctcctc atgcacttca tcgtggcgac
    63901 taaaggaacc gtccgcctcc ttgataaaga aagttagctc atggacgatg gagtgaggtg
    63961 ctgcatcctc ataagtatcc cagagcatgg caaaatcttc cgcattttca tggtaggaat
    64021 agcctggaaa aatttcatcc gtctggtaag tcgaatgcac atcaaagatg aaaactccgt
    64081 cttcgttgag gacattatag acttcttgaa aaacgtcccc tacttccacc tcatcctgca
    64141 tgtagcagat tgagtccgag taacacgtga caaagtcgta ttgacctgcc ttggacaaat
    64201 ccagcatatt accttccata aaatcaatct tttgcttggc tgaagccgct ctcttttcgg
    64261 caattttcaa catatctgcg ctcaagtcca gtccagtcac atcaaaacca gcctgagaga
    64321 agcgcactga ttgaattcct gtcccacaag ccaattccaa gagtttcttt ctctccttag
    64381 tttttggcaa atgacgcaga gaaaaatcag tccatttgtc gtataaactg tcatccatga
    64441 cctcatcata gaccgccgca aaagtttcat aagttgccat aatcatgata ccaagagcct
    64501 ccatggtaaa caccattcgc cctttacctt tctatccatt ttcttctaaa ataagcaaat
    64561 aaaacccagt tgactacaac tgagttcaat tgtacactat agtcttttcg tttgctttta
    64621 gtactaggca acgagttgca ggcataactg gagttaggca aaacgagtta acgccgtaat
    64681 aaaagataaa ggaaaagact ataaagtttc agataaatct acagaatgcg cctcatgcca
    64741 tagtttttct aggttatagt gggcacgcat ttcttctgag aagatatgca cgacaacagc
    64801 accaaggtcc agcaagaccc agcctccagt tgcatcacct tcgatatggc tacctttaaa
    64861 gcctgcttga gctacttttt cacggatatt gtcagcgata gcatccaact gacggctatt
    64921 cattgaacta gtgataacaa agtagtctgt cacgctggtc aaatcttgta catcaagtgc
    64981 gaggatatcc tctgcacgtt tctcatcagc cgctttcacg actagttcta gtaattcttt
    65041 ttcgttcatt tagtcctctt tcaaatagtg cacaaaggcg ttataggttt caagggtttg
    65101 gggataaatg ggaaatccct gatgagctag atgctccacg gtatgaactg tttcgtaggc
    65161 caccgcctta ttaagcgata gactcgcaat ctcacgcgcc acgtccactc caggaaaggc
    65221 tcgattgtgc tcgatatagt ctgcgacgta gataactttg tctaggtcgg tcatctgacc
    65281 agcaccgact gtatggattt caatggctcg tagaatttca gaatcatgca aattcaaatc
    65341 ttcctgaatc ttgtaaattc cgaccatacc atgccagaca ttattgcccc agtttttgag
    65401 gtcggggtct aactgataac ggtcaatcaa gtctaaaaat tcctgatctg acagcttttt
    65461 agcatagtca tgaagaaggc ctgctagacc tgctttctca acatctactc caaatctctc
    65521 tgctagttct atggctgcaa gctccacacc caagcagtgg gttaaacgtt tttcaggtag
    65581 aagctctgcc attttttcca acaaagcctc acgggagcag ttgatatagt cttgataggc
    65641 catcagtaga gcccctcctt ctctatgtag tccagtacag gctgaggtag gagaaagttg
    65701 ggtttccgcc cttgagcaat gaagtcacgc accatgctgg atgagatgtc catgagaggc
    65761 acatccaccc agataactgg ataggaagtt ccagccttat agcgcgggcg ctgaacccct
    65821 acaaactgaa ccatgtcaac cagctcatca attcggtacc acttaggcag atagtccacc
    65881 atgtcggcac cgatgataaa gtaataatcc gtatctggat gttgctctgt caagattttc
    65941 atggtgtcgt aggtgtagga aatgcccttg cgctccaact caatggtttc aatggctaag
    66001 ccttcaatcc cctcaatcgc caactcaagc atcttgagac gatggtgttc agggatggtt
    66061 tcctttttat ctacgtgagg aggttggtat tcaggcataa gtagaacttg gtccagtccc
    66121 aactgctgcc gtacttgatc cgcaacaatg agatgggcat tgtgaacagg gttaaaattc
    66181 ccccctaaaa tcccgatttg tttgcgtttt ttctccttga tttctggctc caactctacc
    66241 ttggtaaagg gagtcaataa ttcgattgcc ataggctagt ctcctttatt tctctgtaaa
    66301 aacagttatt tggagtttcg gtcttagatt tctttgactt tcttagaaat cttgcgattt
    66361 tctttcttgc tagattgttt aaacaaaatc aagatgcgtc ctattttttg gactgtatcc
    66421 acaccgattt cttcttccaa aatttcagct acttcgtgga tgttttcatc tgtgttttgt
    66481 aagagagtaa ccttgattaa ttcacgcgca tcaagagctt gacggacgct ggttttgatt
    66541 tggtcgttca gtccattttt cccgatttgg atgataggtt tgaggatgtg tgcctggctg
    66601 ttgaggaagg cacgttgttt tgatgttaat gacataattt tcttccttgt tttttgatag
    66661 ttattttagg tggtgaggga cggtcggaac taattttcca aagatttcat ctttgaaaaa
    66721 tggatttcct gacctcacaa ttgagccttg gtctcaattg tgccccttgc caatctacag
    66781 attggcaatc acaccacggc aataactatc gctatatgag ctcactttgt tcgctcagcg
    66841 attttgtttt aaataattgc ttttcgtatg acgacggcga cgccttctgg tgcccagacg
    66901 gcgacttttg ctatgcctgt tacacgaatc caacctaggc ctgagatgac taggtctgtc
    66961 ttatctttaa tggtaaagac acgctggact aaccttggga aatcttcttt ttccttgcta
    67021 tttggtggtg tcagaagagt tcccaggtgc ttatcgtaga aagtactagc tccttcaagc
    67081 ttgctacggt ggagtttgag ttcattatca aagaaagcag taaatccttg cttttctcct
    67141 gctataaagt caaagcgtcc caaaccacct aaaaataggg tttgctcagg attaagctga
    67201 taggtctttg gcttgatttc ctttttagga ctgacatact tgaggttttt ggccgtcaag
    67261 tagtgagcca tctggtggcg gtggataatt cccggcgtat cgtaaatata agatccgtcg
    67321 tcaagcggaa tctctatttt gtccaaggtt gtccttggga agcgtgaagt agtgatgaca
    67381 ttctgatcac ccgtgatttc ttggataata gcattgatta gagttgattt tccaacgttg
    67441 gtcacaccga ccacatagac atcgcggccc ttacggtagt gttcaatctt gtcaatgact
    67501 tccttaatgg catgtttatt ttgtgctgaa gttaggacca catcgactgg acgaagccct
    67561 tcttcatggg cacgtttcat gatccactgg ctaatcttac cagacttaac tgacttaggg
    67621 aggatatctt ttttatttcc taccaagagg acatcattgc ccgagatgaa acgtggtaaa
    67681 cctgggatga cagatccatt aaaatcaaag atatcaatga cattgacaac taaggcatca
    67741 ctgtctccca cctcgtgcaa gagcttgagg aaatcatcgt tcgtcaactg gacatctgtg
    67801 atttcattgt agtggcggag acggaaacag cgttggcaat agacttcgcc agtctccaaa
    67861 cctttttcaa gtgccgactg gggggtaaaa ccaagaccag ctttatctgt cgtctgaatg
    67921 gttgctccac aaccaataca gagaatttct tccatagtta gattcctttt ttatatgtaa
    67981 tcggtccgta cttttcagta atttttctca taacacgacg ctcacgagtt cggttaatct
    68041 gcgttttgat tgagtcatgt tggaccaagg gtttgactaa aattgaccga atccctgcac
    68101 ggtgggctgc tcgtatatct gtcatgagct ggtcgccaac catgaccact tcctttttgt
    68161 catagtggaa ttccttcatg gcacggtcaa taccaaatgt gaagggcttc aaggcccagt
    68221 aaacgtaatc aatcccaaat ttctcaactg ctcgttgaac gcgttttttg gtgttatttg
    68281 acaccacgat aatgcgaatg cccgcgtccc gaaggtcatg tagccattgc ttcatctctg
    68341 gcgttccatc agggttgttc caagcaatga gggtattatc caaatcgacc aaaacagcct
    68401 tgattccctg cgcctgcagg cttgggactg tcagatcata gactgcttcc acagcaaaat
    68461 ctggcatata attttcaatc gccattctgg ctccttttct taactttttt tcgcaatttt
    68521 ccttagtaac aaggataaaa caatccataa acctgcacta gccaaactga tatagagcca
    68581 agcatggggc tcatctgtta aaggtaaggg aacattcatt ccgaaaaagc ctgtcacgac
    68641 tgccaaaaca gctagcaaga ctgaaatgat agtcaaggtt gtcaaattgt cattcagatt
    68701 attgtttaga atattgttgt aagaggctga aagctgctgt aaaatctgag agattaggtc
    68761 tgtcatggat accagctgat gagcctcaat catggcatca tcaaactgtt ctctctcaat
    68821 ctcatcaaaa ctacgataca aggcatgacc ttgaatatgc tctaacaaaa tccgattttg
    68881 tttggcagct gccgtcagat aaaccatacc agtctccaaa tcagacaggg caaagaggtt
    68941 tttcttggta gttcgctggc gcaagaggtc attgacctca tccctactct tgtccatctg
    69001 ctcaatgaca ggatagtagg cattgctgat gatttccaga ctggcaaaga gaaacttata
    69061 aatcgaaagc gtgtcatggc tctccagata acgagtcatc tgttcaatga cataggcgtt
    69121 cttggtattg ctaatggtaa tcaggcgacg atgctccacg ataaaggtca tgggaaaagt
    69181 ctcatagtag gccttgtcct tttttacgtc taggacatta tagataaagg taaccgtccc
    69241 actttcacgg tggtagtcca tgtgggcgcg ctcgtttcta tccagtgcgt attcaatggt
    69301 ttccttgtcc aaaccgtaaa tttcagaaag gtcttctagt ttattcaact ttcctagatc
    69361 taggtctatc caggtacaac cattgcccaa ctgcttttct aaaaccatct tttctcctta
    69421 ttaaactccc tctattgtac cacaaattac ttaaaataac aggtctagtc tgtgcgtgag
    69481 aaattgctaa caactgtgat atttcggtta gggacaaagt gaagggcttg ctcctcgcta
    69541 cgaagctgtg tcgtacgaat tcccacactg acaaccttac ccgatacagt aatcggtcca
    69601 tttgtcagaa cgacctcatc tcccacatcc agttgacgtt caaagaggat gaaaaagcca
    69661 ttgataacat cagacagaaa gccttgggct cccataccaa tcgctacccc agcaatacca
    69721 gctccagcca gcaaactaga aactggcaaa cctaaaatcg acaaaatgca gtagagtaaa
    69781 aagaaatata gcgtataatt aaacacattt tctagtaaac gtgagatggt tttttggcgt
    69841 ccgacatcat gacgagacat ttttagagag gggttgacaa ttctctgcac catggtatga
    69901 agcatttttt tagcgatata aaatacaatc aaaagcagta aaagagaaat gaccttggtt
    69961 agaatattct cgataatggt tgtcacatct agcttttcaa tataagcctg aataaatttt
    70021 tgcatataaa actcctttat ttcattatac catattttca tcagtctcat tctccataaa
    70081 tattcaaaaa atagacagaa aattcttgat tttgtctatc atttatacta taatcataac
    70141 cactacacaa aaaggagatt attatgaaaa gaatcattca tgcttggaat aaggcaagcc
    70201 ttgtcaagcg tatcttgatt ggtatgcttt gtgggggaat cctaggactg acccttccta
    70261 atctctcagg gattgggcta ctcggggatt tattcgtcgg aggtctaaaa gctgttgctc
    70321 ctatcctagt ctttgccctc gttgccaatg ccctttccca acatcaaaag ggacaagata
    70381 gcaatatgaa aacggttgtt ttcttgtata tcctagggac ttttgccgct gctcttgtag
    70441 ctgttgtagc tagtttcatc gtccctattg aaatcaccct aaatagtgcc aataccgaaa
    70501 ttgctccacc agatgggatt ggacaagtcc tcagcaacct cttgctcaaa ctggttgaca
    70561 atccagtcaa tgccctcatt actgccaact acatcggtat cctatcttgg gcagttgttt
    70621 tcgggattgc catgagagag gccagcaaaa atagtaaaga attactaaaa actatcgctg
    70681 acgtgacttc taaaattgtc gaatggatca tcaatctggc tccatttgga atccttggtc
    70741 ttgtttttaa aaccatttct gacaagggaa tcggaagccc tgccaactac ggtattttat
    70801 tggttctatt agtaacgact atgctttttg ttgcccttgt ggtcaacccc ttgattgcct
    70861 tcttctttat gagacgcaat ccttaccctc tagtttggaa ctgcctccgt gtcagcggtg
    70921 tgacagcctt cttcactcgt agttctgcgg ctaacattcc tgtcaacatg aaactctgcc
    70981 atgaccttgg actcaaccca gatacctatt ctgtttctat cccactcggt tctactatca
    71041 acatggccgg ggcagcgatt accattaacg ttttgaccct tgctgcagtt aacactcttg
    71101 gaattcctgt tgactttgcc acagcctttg tcctcagtgt ggtagcagct atctcagcct
    71161 gtggtgcttc tggtattgct ggaggttccc tcctccttat cccagttgct tgtagccttt
    71221 tcggtatttc taacgatatt gccatacaag ttgttggggg tggttttgtg attggtgtca
    71281 tccaagactc atgtgaaaca gcccttaact cttctacaga tgtcctcttt accgccgttg
    71341 ccgaatacgc agcagcccgt aaaaaataac tcataaaggc aagcctgctc aggtcttgtc
    71401 ttttacgctt ttattctaac ttatcaggaa attcttatgt ctattagcca acgtacgacc
    71461 aagctcatct tagctacctg tcttgcctgt tttcttgctt attttctcaa tctttcctca
    71521 gcagtttcgg ctggaattat cgctctcttg agcctatctg atacgcgtag aagtacctta
    71581 aaactggctc gcaatcgact cttttccatg ctcctagctc tggctatcgg tgttctagct
    71641 tttcacttga gcggatttca tatctggagc cttggtctct atcttgcctt ctatgtgcct
    71701 ctagcctaca agatgggctg ggaaattggc atcacaccaa gtactgtttt ggttagccac
    71761 ctcttggtac aagagtcaac ctctccagac cttctagtca atgaattctt tctctttgct
    71821 atcggtacag gatttgcttt actggtcaat ctctacatgc cttcacgaga agaggaaatc
    71881 cagcactacc acacgctggt ggaagaagcc ctcaaactgg tctatttaga tcactctgac
    71941 cacctctttc accaaaccga ctaccatatc cactactttg agatgagaca gcgacaaagg
    72001 cgtatcctgc gaaatatggc ccagcaaatc aatacctgtc acctagctgt cagtgagagc
    72061 ctgattttag cacaactctt ttcaaaaatt gccggtcaac tgagtcagac caatcctgct
    72121 tctgatttgc tagatgaaat tgaacgctat ctggaagtct ttcgaaaccg cagtctgccc
    72181 aagacaagag acgaatttga aacccgcgcc acccttcttc aactcctacg tgaagccaaa
    72241 accttcatcc aagtaaaagt tgacttttat caaaaatatg gacagtaaaa aataaaacca
    72301 ctaaaaaaca gagcttgcta gctcttttga aaagtagtat aattattgca tgcgcaatca
    72361 tcttgtgacg caaagactgt ccgtgaatgg actttcttct atttacaact ctaaaaagaa
    72421 aggagatact atgacctatt tggaaaaatg gtttgacttc aatcggcgtc agaaagagat
    72481 cgaaaccttg ttagaagaca ccattgccca gcagagtgaa caaagtctga ccttgaaaga
    72541 gttctacctg ctctactatc tggacttggc tgaagaaaaa tctctacgcc agattgatct
    72601 gccagataag cttcatctga gcccgagcgc tgtttctcgg atggtggctc gattggaagc
    72661 taaaaattgc ggtctgctta gtcgcatgtg ttgccatcaa gatagacgct ctagctttat
    72721 ctgcctgaca agtgatgggc aaaagacact ggcctctcta cagaaagctg tcgaaacaag
    72781 cttggaaact ggtttggatt tcttgattta agatgatttc ggaagaatgt tgcgtgcgca
    72841 agcatttttc ttgacattct cttttacaag gagtaaaata aagtcatcat taaaaaagga
    72901 gtttttaaat gattgaaatt acctatctag atgccagcaa gaacgaaaga actgtaacct
    72961 tcgattctta tgaagacttt gatcgttcgc aacaagcttg ccttatcggc gtcgcagact
    73021 actaccctgt ccaaaaatta acttacaagg gttatgattt ggactatcat gggacttatg
    73081 gagatgtctt cttctatctc atgaaacaag atttaagcca atataactaa aaaaggagaa
    73141 atacaatggc aaaggcaatt acagatgcaa cattcgaaca agaaacaaaa gacggtttgg
    73201 tcttagtaga cttctgggca acttggtgtg gtccatgtcg tatgcaaggt ccaatcttgg
    73261 acaaattgtc tgaagaactt tcagaagatg tcttgaaaat cgttaaaatg gacgtggatg
    73321 aaaatccaaa cacagctcgt gcttttggaa tcatgtctat cccaactctt ctcttcaaaa
    73381 aagacggcca agtagtgaaa caagttgctg gtgttcacac agcagaccaa atcaaggcca
    73441 tcgttgctga attgagctaa tcaaacgaga gaccaagtac tttctttggt ctcttttttc
    73501 ttgccctttg ccatttttca aaaaatatgc tagactatag tagattgaaa ctagaatagt
    73561 acacctctac ttctaaaaca ttgttagaaa tcgatttgac tgtcctaatc gttttgtcct
    73621 gttcttattt cattttacta tataaataga atattacgat gtttgggata tgccatcgct
    73681 aaaaaaactc gatttggtat tttttagctc cctaatggga gctttttgcg ttctctgaac
    73741 atttcccatt ttggaaggag tactatgaaa cgtcaatcaa ccttggtcgt ctttagtggc
    73801 ggtcaagatt caacaacctg ccttttctgg gccatgcaac actatgaaac aatcgaagct
    73861 gtcacctttg cctacggcca acgtcatcac ctcgaaattc aaattgctag agaaatcgct
    73921 aaggaacagg gcattcgtca ccatatcctc gatatgtctc tactgggaca aatcactgct
    73981 cagccagact ttacgacgat tcatatttcc tacattcctg ataagctctg tgtcgagtca
    74041 aaatccctca atatatctat ctatttagct accgaaacca cggagatttc cacgaaaact
    74101 gtatcaacac catcgggaaa gacttggtca acttgctaga ccctcgctat ttagaagtct
    74161 ggggaaaatt cactccgcgc ggtggcattt caatcgaccc ctactacaac tacggtagac
    74221 ctggaaccaa gtatgacggc ttggcagaac aacgcctctt ccaacacgat ctttatccag
    74281 agaaaattga caaccgttaa actcatactc aatgaaaatc aaaaagcaaa ctaggaagct
    74341 agctacaggc tgctcaaagc agtgtttgag gttatagata agactgacga agtcagctta
    74401 aaacactgtt ttgaggttgc agatagaact gacgaagtca gtaacatata catacggcaa
    74461 ggttaagctg acgtggtttg aagagatttt cgaagagtat catacgaaaa agccctgttc
    74521 ctcaagatga ggagcaaggc tttttgagtt tcaattattc ttctgttcca aggaaatttt
    74581 ttgcaacaag ggctgcaaga actccaccag cgattggtgc aaggatgaaa atccaaactt
    74641 gttgaagggc tgcgccgccc accaagacag ctggtgccaa gctacgagct gggtttactg
    74701 aaagtccagt aatcttcaat ccgacaagaa tcatcgccat caatgacaaa ccgattacca
    74761 aaccagcaat cgcgccattg cccttacttt ctgaagtcac agtcatgata accaagacaa
    74821 ataagaaagt tgcgatgact tcaaacaaga aaccaccaaa gacagtgaca ccgtttgcca
    74881 aggcattttc accaaggcta gcagttgaca tacctgaatt agccaagagg aagaagactg
    74941 cgccagaagc gatgaaagct ccaacaacct gaccaaggat gtagtttaca agttctgaag
    75001 atgacaaacg tttgtttaca aacatagcaa tcgaaacagc cgggttcaag tgagcacctg
    75061 aaacagttcc gattgagtag gctgccacca cgattgctaa accaaaagca aaggcgattc
    75121 caaggtgacc aaggccatca agaccatttc caaaaacaac agctcctgtc ccgacgaata
    75181 caagcatgaa cgtaccgatt aactcagcaa caaatttttt cattttcttt ctcctcgtaa
    75241 tatataatca tggggatatt tcaatcccaa gttttattcg ttatca
//
LOCUS       DAVDZK010000005        64762 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVDZK010000005 DAVDZK010000000
VERSION     DAVDZK010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64762
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.005"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            136..1032
                     /locus_tag="VUX16_000395"
     CDS             136..1032
                     /locus_tag="VUX16_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HET8123435.1"
                     /translation="MVIELKSEQLSVQFNSFGGALSSIKDAEGLEYLWQGDATYWSGQ
                     APVLFPICGSLREDTALYIDEKGQESKGKIPRHGLVRKKEFELVEQTDKSVTFAIEDD
                     ENSYQNYPYHFRLEITYSLTGKTVRTQYKIFNKETSKVMPYFIGGHPGFNCPLLDDEV
                     YEDYYLEFEKEETCSVPRPFPETGMLDFQDRSPWLEGQKEIDLSYDLFSTDAVTLDEL
                     QSRTIALRSRKHDKGVKVHFAEFPNLIIWSTLNKGPFIAFEPWSGLSTSLEEGDHLED
                     KKNVRLLEANQVEEIGFEIEVL"
     gene            1190..1615
                     /gene="lacA"
                     /locus_tag="VUX16_000396"
     CDS             1190..1615
                     /gene="lacA"
                     /locus_tag="VUX16_000396"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET8123436.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGRDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1646..2161
                     /gene="lacB"
                     /locus_tag="VUX16_000397"
     CDS             1646..2161
                     /gene="lacB"
                     /locus_tag="VUX16_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET8123437.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            2172..3101
                     /locus_tag="VUX16_000398"
     CDS             2172..3101
                     /locus_tag="VUX16_000398"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET8123438.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTINRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIKGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            3103..4083
                     /gene="lacD"
                     /locus_tag="VUX16_000399"
     CDS             3103..4083
                     /gene="lacD"
                     /locus_tag="VUX16_000399"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET8123439.1"
                     /translation="MALTEQKHVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            4342..4959
                     /locus_tag="VUX16_000400"
     CDS             4342..4959
                     /locus_tag="VUX16_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123440.1"
                     /translation="MATKKSFKALVVGLGIVSIFSSALPMVSGSVFADSALTTVDKAN
                     DIVLNVDGNKFYNVSVSEDIVNAGQILEDYFYVDKFGNINLKGTPEELSKNIGISVQE
                     ASLMYEAVKELPNVYERGPVGFRFNLGPQVRGMGGWAAGAFATGYAGWHLKQFAVNPV
                     TSGFVAVISGAIGWAVKTAVENYWTVAVATVEVPFVNLVYTIDLP"
     gene            5357..6193
                     /locus_tag="VUX16_000401"
     CDS             5357..6193
                     /locus_tag="VUX16_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET8123441.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLKGYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6229..6546
                     /locus_tag="VUX16_000402"
     CDS             6229..6546
                     /locus_tag="VUX16_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET8123442.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6546..8237
                     /locus_tag="VUX16_000403"
     CDS             6546..8237
                     /locus_tag="VUX16_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET8123443.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIENGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVVLAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            8409..9815
                     /gene="lacG"
                     /locus_tag="VUX16_000404"
     CDS             8409..9815
                     /gene="lacG"
                     /locus_tag="VUX16_000404"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET8123444.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDHENPADVRAAELEDIIHNKFILDATYLGHYSEKTLAGVEAILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGKKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQVIE"
     gene            9858..10106
                     /locus_tag="VUX16_000405"
     CDS             9858..10106
                     /locus_tag="VUX16_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET8123445.1"
                     /translation="MFKDFIQSIYEKVYIINFDKCSQIPCLTNEELKSLGKWYVYTGK
                     EWICHSDYELEEFKNIFLNFINPEEWDTISFDSDFMPF"
     gene            complement(10398..11159)
                     /locus_tag="VUX16_000406"
     CDS             complement(10398..11159)
                     /locus_tag="VUX16_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET8123446.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIARFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFELSKLTKVIKP"
     gene            11338..11424
                     /locus_tag="VUX16_000407"
                     /pseudo
     CDS             11338..11424
                     /locus_tag="VUX16_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(11493..12455)
                     /gene="nrdF"
                     /locus_tag="VUX16_000408"
     CDS             complement(11493..12455)
                     /gene="nrdF"
                     /locus_tag="VUX16_000408"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET8123447.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNLGQDPLFPDSADD
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDNDYNYGLD"
     gene            complement(12643..14802)
                     /gene="nrdE"
                     /locus_tag="VUX16_000409"
     CDS             complement(12643..14802)
                     /gene="nrdE"
                     /locus_tag="VUX16_000409"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET8123448.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKANDGEYYLESMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYAKGSYFDKYITGEFVPKSERVKELFKDVFIPSAADWAELRDKVQ
                     ADGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKKENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(14883..15101)
                     /gene="nrdH"
                     /locus_tag="VUX16_000410"
     CDS             complement(14883..15101)
                     /gene="nrdH"
                     /locus_tag="VUX16_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET8123449.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            15451..15714
                     /locus_tag="VUX16_000411"
     CDS             15451..15714
                     /locus_tag="VUX16_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET8123450.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            15720..17453
                     /gene="ptsP"
                     /locus_tag="VUX16_000412"
     CDS             15720..17453
                     /gene="ptsP"
                     /locus_tag="VUX16_000412"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET8123451.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFNEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            17588..18082
                     /locus_tag="VUX16_000413"
     CDS             17588..18082
                     /locus_tag="VUX16_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HET8123452.1"
                     /translation="MSKEIDIEYYHQLALQKQKEHRKVLANLKKKPPKNLDKIAQQIH
                     QEVFEEIDCTACANCCKTLGPDFKEADITRIAKYFKMKLPAFEAEFLQVDEDGDKVFK
                     SMPCPFLGGDNLCSIYDVRPKACREFPHTDRKKIHQINHLTIKNTLTCPAAYLFVEKL
                     KDKL"
     gene            18140..18712
                     /locus_tag="VUX16_000414"
     CDS             18140..18712
                     /locus_tag="VUX16_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET8123453.1"
                     /translation="MPRPKTKEELVLASKENYDKLNRFISQLSEDELQTPFDFSKDQK
                     KKEAHWKRDKNLRDVLIHLYEWQQLLLTWVHSNQKGHERPFLPEPYNWKTYGKMNVTI
                     WKKHQKTSLEEATRLLEQSHREVLELMEGFSNDELFAKGIYKWTGGTSLGSYFVSSTS
                     SHYDWALKKIKAHQKNCKMQMDSLKKNEFF"
     gene            complement(18774..19763)
                     /gene="dhaQ"
                     /locus_tag="VUX16_000415"
     CDS             complement(18774..19763)
                     /gene="dhaQ"
                     /locus_tag="VUX16_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DhaKLM operon coactivator DhaQ"
                     /protein_id="HET8123454.1"
                     /translation="MTFISNHKQKIISSYISATVSSHPELEKHPTLPLVYQKNRNPHQ
                     VPILSGGGSGHEPAHIGYVGEGMLTAAIYGQLFTPPTRTEILESIRFLNNGHGVFIIV
                     KNFEADIKEFSWAINTARQEGIKVGYSLAHDDISIEPHNRFQIRGRGLAGTILLHKVL
                     GYAAQNGADIEQLTDLGHELAPEIATIGFATKSASLPQATLPLFNLEEGNISYGIGIH
                     GEEGYRIVPFQSSEILANEIISKLRLHYHWKKGDQFILLVNNLGTTSNLEMGIFINDI
                     LQLLEIEGVTITFIKSGTFMTSLDMAGISVTLCPVKNKQWLKALNAPTTAFAW"
     gene            complement(19760..20290)
                     /gene="dhaS"
                     /locus_tag="VUX16_000416"
     CDS             complement(19760..20290)
                     /gene="dhaS"
                     /locus_tag="VUX16_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000168609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase transcriptional
                     activator DhaS"
                     /protein_id="HET8123455.1"
                     /translation="MASSLITKKRIAKAFRDLLATREFDKISIVDIMESAGIRRQTFY
                     NHFLDKYELLDWIFETDLTEYITNNLDFISGQKLLQELFLYFEQERDFYIQLFDIQGQ
                     NNFYDQFISYCRLLVSKILREYGQIDIDSSAYTCFLLDYHSHALAEIVKAYVNKKSPV
                     PQPDFLIMTIIGKRPQ"
     gene            20444..21433
                     /gene="dhaK"
                     /locus_tag="VUX16_000417"
     CDS             20444..21433
                     /gene="dhaK"
                     /locus_tag="VUX16_000417"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HET8123456.1"
                     /translation="MKKIINKPTQVVDEMLQGLSFMHDDLVERLDGFDVIVRKVEKTG
                     KVGLISGGGSGHEPSHAGFVGDGMLSAAICGAVFTSPTPDQILEAIKAADEGAGVFMV
                     IKNYSGDIMNFEIAQELAEMEGIDVASVVVDDDIAVENSLYTQGRRGVAGTILVHKIL
                     GAAARSGKSLSEMKDLADKLVLEIKTIGLALSGATVPEVGKPGFILEDDEFEYGVGIH
                     GEPGYKKEKMQPSAQLASELVEKLSEGFQLKAGERYGLLINGLGSTPLMEQYVFANDV
                     AKLLHEKGVELSFKKIGNYMTSIDMAGLSLTLIRLANDEWLDALNAPVTTPAW"
     gene            21455..22030
                     /gene="dhaL"
                     /locus_tag="VUX16_000418"
     CDS             21455..22030
                     /gene="dhaL"
                     /locus_tag="VUX16_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HET8123457.1"
                     /translation="MNAEQALEWMKLFNEKIQEQKDYLSELDTPIGDGDHGGNMARGM
                     AAVMENLEGKQFETSSDVFKVVSMQLLSKVGGASGPLYGSAFMGMSKADSHSKLEEIL
                     QSGLDMIVKREKAVVGEKTMVDVWTPAIAALSDGQLTHELIDKVVNATKDLLATKGRA
                     SYVGERSLGHIDPGSFSSGLLFTAILETGVV"
     gene            22030..22404
                     /locus_tag="VUX16_000419"
     CDS             22030..22404
                     /locus_tag="VUX16_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002960428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HET8123458.1"
                     /translation="MESIGLVIVSHSKNIAEGLVELISEVAKDVPITYVGGTEDGGIG
                     TSFDQVDRVVSENPADTLLAFFDLGSAKMNLEMVADFSDKSIMINRVPIVEGAYTAAA
                     LLQAGAELSVIQTQLSELEINK"
     gene            22852..23565
                     /locus_tag="VUX16_000420"
     CDS             22852..23565
                     /locus_tag="VUX16_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET8123459.1"
                     /translation="MSYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQGKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIDRDYDLYAATNGITAIQTGRLAQSGLEPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVH
                     SYQDLLDCLDKNILEKITF"
     gene            23579..24028
                     /locus_tag="VUX16_000421"
     CDS             23579..24028
                     /locus_tag="VUX16_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123460.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNETVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLNCKKWFR"
     gene            24074..24727
                     /locus_tag="VUX16_000422"
     CDS             24074..24727
                     /locus_tag="VUX16_000422"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET8123461.1"
                     /translation="MEHSSWHALIKEQLPKGYFGKINQFMEQVYAQGTIYPPKEKVFQ
                     ALLTTPLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAVQANGHAGQIWEPFTDAVIQVVNQLDKPVVFILWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANALLKETGQEPIDWLR"
     gene            24737..25201
                     /locus_tag="VUX16_000423"
     CDS             24737..25201
                     /locus_tag="VUX16_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET8123462.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            25214..26482
                     /locus_tag="VUX16_000424"
     CDS             25214..26482
                     /locus_tag="VUX16_000424"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET8123463.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQEVLQSAAKDKINVKTVATITKNFNGQDLTDFKALLEVGAVGFSDDGIPLESSKVV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAKEHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAQVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPSKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            26496..26756
                     /locus_tag="VUX16_000425"
     CDS             26496..26756
                     /locus_tag="VUX16_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123464.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPASNRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            26767..28128
                     /gene="pdrM"
                     /locus_tag="VUX16_000426"
     CDS             26767..28128
                     /gene="pdrM"
                     /locus_tag="VUX16_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET8123465.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            28282..29250
                     /locus_tag="VUX16_000427"
     CDS             28282..29250
                     /locus_tag="VUX16_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET8123466.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRCMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESVFEDIYAD"
     gene            29266..30233
                     /locus_tag="VUX16_000428"
                     /pseudo
     CDS             29266..30233
                     /locus_tag="VUX16_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
     gene            30450..31493
                     /locus_tag="VUX16_000429"
     CDS             30450..31493
                     /locus_tag="VUX16_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET8123467.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYSEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            31557..33242
                     /gene="lpdA"
                     /locus_tag="VUX16_000430"
     CDS             31557..33242
                     /gene="lpdA"
                     /locus_tag="VUX16_000430"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET8123468.1"
                     /translation="MPKVGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPVMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIATKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            33310..33666
                     /locus_tag="VUX16_000431"
     CDS             33310..33666
                     /locus_tag="VUX16_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET8123469.1"
                     /translation="MMKYIFSEEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFT
                     SGKVEVFANVTESKIQDIKIYGDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITR
                     YFAGISREEIAEAVVG"
     gene            complement(33732..35009)
                     /gene="ltrA"
                     /locus_tag="VUX16_000432"
                     /pseudo
     CDS             complement(33732..35009)
                     /gene="ltrA"
                     /locus_tag="VUX16_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(35710..36780)
                     /gene="xerS"
                     /locus_tag="VUX16_000433"
     CDS             complement(35710..36780)
                     /gene="xerS"
                     /locus_tag="VUX16_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET8123470.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDLVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(37364..38914)
                     /locus_tag="VUX16_000434"
     CDS             complement(37364..38914)
                     /locus_tag="VUX16_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET8123471.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQILGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(38930..39709)
                     /locus_tag="VUX16_000435"
     CDS             complement(38930..39709)
                     /locus_tag="VUX16_000435"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET8123472.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(39696..40547)
                     /gene="ylqF"
                     /locus_tag="VUX16_000436"
     CDS             complement(39696..40547)
                     /gene="ylqF"
                     /locus_tag="VUX16_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET8123473.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTCALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(40807..45921)
                     /locus_tag="VUX16_000437"
                     /pseudo
     CDS             complement(40807..45921)
                     /locus_tag="VUX16_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(45970..51186)
                     /locus_tag="VUX16_000438"
     CDS             complement(45970..51186)
                     /locus_tag="VUX16_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HET8123474.1"
                     /translation="MEKYFGEKQQRFSFRKLSVGLVSATISSLFFMSVLGSSSVEAQE
                     TQETKGVHYKYVTESELSSDEKKQLVYDIPTCMENDDETYYLVYKLNSQNQLGELPNT
                     GSKNDMKTLVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSAHALENN
                     LLLNYNTDYELTTGEKLPLPKEISGYTYIGYIKERNITSESKVNNQEKSVDTSKNQQK
                     VDYTIAPNFIESPSKIQVINGQYETVPEFRDGQVGAVATESAATKADTLSSDMNSEVE
                     SHSIPPTVDSSQNGENLGKQGEDATPVEKPKEQEPEKTEEVPVNPTEGTTEGTSNQGA
                     KNPVQPAEESTTNSEKISPDTSNENTGEVSSNPSDSKPPVEETNKPEKDESKDETSTK
                     PENSAHPITESGQTEPDQPKGNSPEDVSTESKTSNSNESEEIKHKTEVEPDKKVEEQE
                     KTIELRSVSDVELYSYEGNQSKQHTSLDKVPDNKSAYFIKVKSAKFKDVLLPVSNIED
                     TTKDGKAVYKITARLEHLKQSVDNQYQDNFTYYLPKLVQNDSPIYTSFKKLITDMNSR
                     PSGTFTLGATMNAREFELNENQESYVTSKFTGTLIGSHQGKHYAIYNLKKPLFNTLNN
                     ATIQNLTLKDVNISGKNHVASVAKEATNSSTLDNVHANGIIAGELGIGGLVQKVDNST
                     ISNSSFTGRITNTFVTTSQYAIGGLVGQLTGTNASVDRSIATVTISSNAEYSNQTIGG
                     IAGIVENNATVQNSYAEGEINNVKPFARVGGVAGSLWTNGSSTEDNSGILQNVLSDMN
                     ITNGNAISGYHFNGMKKKAVYSNKDNKVVNVQAVGDEVMSIDSTVERGTEIEKTAVQA
                     KKEQITKKHTITVEDFTNSVKQDVDYTKATHYQVARDIAYKNIEKLLPFYNRDTIVKY
                     GNQLSTDHNLFKKELLSVVAMKNEEVVSDITSNKNSINHLLLHYKDGTSEKVNVTYHS
                     DFANLAEYTIGTTGLVYTPNAFLKDYTSIIDRVKNDLNTVQYDPTSLKNLLGISDNVK
                     LTELYLDEQFAKTKEHLTETLKKLLSADAAVSGNNDIIDNYIVDKIKRNKEALMLGLT
                     YLERWYDFKFDKASAKDLLMFHMDFFGKGNTSPLDTIIELGKSGYNNLLAKNNVVTYN
                     ALLTNNYGTKDLFSALEGYRKAFAPTQTNNDWFKSQTKAYIVEEKSNILEVKANQEKA
                     GSKYSIGVYDRITSDSWKYRNMVLPLLTLPEKSVFVISTISSLGFGAYDRYRNKEHQA
                     SGDLNSFVEENARETAKRQRDHYDYWYRILDEKEREKLYRNILLYDAYKFGDDHTEGK
                     AKKVATFDDPNPAMQHFFGPVGNKVGHNEHGAYATGDAVYYMGYRMLDKDGAITYTHE
                     MTHDSDQDIYLGGYGRRSGLGPEFFAKGLLQAPDHPNDATITINSILKHSKSDSTEGQ
                     RLQVLDPTTRFNNADDLKQYVHNMFDVIYMLEYLEGKSIISQLSATEKMTALRKIENK
                     YVKDREDGNEVYATNVVQNLTEEDAKKLTSFENLIDNNILSAREYKSKEYERNGYFTI
                     KLFAPIYAALSSDIGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEVAKQNGKKI
                     TIYGKERGLVTDELVLQKVFNGQYETWTEFKKAMYNERVAQFDRLNKVTFNDTTQPWQ
                     TFAKKTTSSVDELQKLMDVAVRKDAEHNYYHWNNYNPDIDSEVHKLKKAIFKAYLDQT
                     DDFRSSIFENKK"
     gene            complement(51425..52603)
                     /locus_tag="VUX16_000439"
     CDS             complement(51425..52603)
                     /locus_tag="VUX16_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123475.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLPLDQQLEEEEKLLRKVENLTKKV
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFSPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERVYQDYFGFTETLTQEERKWAKIFFGKNRTERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNPYFRELPEEKSRLARLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKESLQADHLSSAQESWIEGILLNCIKPFLERLVI
                     "
     gene            complement(52621..56271)
                     /gene="addA"
                     /locus_tag="VUX16_000440"
     CDS             complement(52621..56271)
                     /gene="addA"
                     /locus_tag="VUX16_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET8123476.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGHGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHGDTWKLAKTFQTFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILEKFPQVREAYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAKNPHEGKLILLKENFRSSSEVLSATNDVFEGLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKVEFLLYDKDDTGEEEEGQAETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIGMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKEYPAAK
                     NGKLNSTTRLQARNFQDWLWAVSKVFTKDKLNFSYRFVGEDQLTREAIGELKTKSPLQ
                     DSSQADNRQSETIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVDKKISFDLPDFSSKEKVTGAEIGSATHELMQRIDLSQQPTLASLTETLK
                     QVQTSPAVRDKINLAKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYEGRIVLFDYKTDRYDEPSQLIDRYRGQLALYGEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(56268..59543)
                     /gene="rexB"
                     /locus_tag="VUX16_000441"
     CDS             complement(56268..59543)
                     /gene="rexB"
                     /locus_tag="VUX16_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET8123477.1"
                     /translation="MKLLYTDIRTSLTEILTRKAEELVAAGKRVFYIAPNSLSFEKER
                     AVLEYLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLRYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLIAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(59743..59901)
                     /locus_tag="VUX16_000442"
                     /pseudo
     CDS             complement(59743..59901)
                     /locus_tag="VUX16_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            60072..60716
                     /locus_tag="VUX16_000443"
                     /pseudo
     CDS             60072..60716
                     /locus_tag="VUX16_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            60816..61025
                     /locus_tag="VUX16_000444"
                     /pseudo
     CDS             60816..61025
                     /locus_tag="VUX16_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            60925..61374
                     /locus_tag="VUX16_000445"
     CDS             60925..61374
                     /locus_tag="VUX16_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET8123478.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSSLQRANERLKKPIPKHLSPHIFRHTTISILSE
                     NKIPLKTITDRVGHSDSEVTTSIYTYVTKNMKDEAINVLDKVMKKIF"
     gene            complement(61512..62816)
                     /gene="eno"
                     /locus_tag="VUX16_000446"
     CDS             complement(61512..62816)
                     /gene="eno"
                     /locus_tag="VUX16_000446"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET8123479.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            62980..63426
                     /locus_tag="VUX16_000447"
     CDS             62980..63426
                     /locus_tag="VUX16_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET8123480.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(63423..64538)
                     /locus_tag="VUX16_000448"
     CDS             complement(63423..64538)
                     /locus_tag="VUX16_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET8123481.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVEYLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGSGGGLAGGLCAFAQASIVSGIDTCLDLINFNKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(64547..>64762)
                     /locus_tag="VUX16_000449"
     CDS             complement(64547..>64762)
                     /locus_tag="VUX16_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HET8123482.1"
                     /translation="KKETLEKWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCAK
                     EVLKKEIPHHVDKRDFLEVLPLIDRLE"
BASE COUNT        19173 a        12360 c        12915 g        20314 t
ORIGIN      
        1 catatctacg tcaaggcgac gctgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccattaggag tgacagccta gttttttata aactatcaag
      121 aaattggaga aaataatggt aattgaatta aaatcagaac aattaagtgt tcaatttaac
      181 agttttggtg gggctctttc ttctataaag gatgctgagg gactggagta tttgtggcaa
      241 ggggatgcta cttattggag tggacaagct cctgttctct ttccaatttg tggttcattg
      301 agagaggata cagccctcta tatagatgag aaggggcaag aaagtaaagg aaagattcct
      361 cgtcatggtc tggttcgtaa gaaagaattt gaattagttg aacagacaga caagagtgta
      421 acttttgcaa ttgaagacga tgagaatagc tatcaaaact atccttatca tttccgccta
      481 gaaatcactt atagccttac tggaaagaca gtacggactc aatacaaaat atttaataaa
      541 gaaactagca aggtcatgcc ttactttatt ggtggacatc caggatttaa ttgtcctcta
      601 ctggatgatg aggtctatga agattactat ttagagtttg agaaagaaga gacttgctct
      661 gttccacgtc ctttcccaga aacggggatg ctggattttc aagatagaag tccatggcta
      721 gagggacaaa aagaaataga tcttagttat gatcttttca gcacagatgc agtgactttg
      781 gatgaattgc aatctcgaac aattgccctt cgttctcgta aacatgataa gggggtgaaa
      841 gtgcactttg cagagtttcc aaacctcatc atctggtcaa ctttgaataa gggacctttc
      901 attgcctttg aaccatggtc tggcttgtca acatcccttg aagaaggaga tcatttagaa
      961 gataagaaga atgttcgtct cttagaagcc aatcaggttg aagaaatagg gtttgagata
     1021 gaagttttat aaaaaagtaa aaaataaata acaaaaaaca aacacaaact gttgactttt
     1081 tcaaacaata gtagtatatt atgtttgtga ggactaattg actgtttttt aaagacagcc
     1141 aatacactgc tggaatccag catagaaaaa ataaaaagga gtatacaata tgtctattgt
     1201 tatcggtgca gatgctgcag gtttgagatt gaaagaagtt gtgaaagatt tcttagaaaa
     1261 agaaaatttc caccttgtgg atgttacagc tgaaggtcga gactttgttg atgtgactct
     1321 cgctgttgct gcagaagtaa acaaagaaga acaaaacctt ggtatcgtga ttgatgctta
     1381 tggagctggt ccatttatgg ttgcaacaaa aatcaaagga atggttgctg cagaagtatc
     1441 tgacgaacgt tcagcttata tgactcgtgg ccacaacaac tctcgtatga tcactatggg
     1501 tgcacaactt gttggtgatg aattggctaa aaacatcgct aaaggatttg ttaatggtaa
     1561 atacgacggt ggtcgtcacc aaatccgggt tgacatgttg aacaaaatgg gctaattaga
     1621 ttatagtaag aaaggtaagt taaaaatgag aattgcaatt ggatgtgacc acatcgtaac
     1681 tgatgaaaaa atggcggttt cagaattttt gaaatcaaaa ggatatgaag tcattgactt
     1741 tggtacctat gaccatacac ggactcacta cccaatcttt ggtaaaaaag taggggaagc
     1801 agtaactagt ggtcaagctg atctcggggt atgtatctgt ggtactggtg ttggtatcaa
     1861 caacgctgta aataaagttc caggtgttcg ttctgccttg gttcgtgata tgacaacagc
     1921 cctttatgct aaagaacaat tgaacgctaa cgttattggt tttggtggta aaattactgg
     1981 tgaattgctt atgtgtgata tcatcgaagc tttcatccat gctgaataca aaccaactga
     2041 agaaaacaaa aaattgattg cgaaaattga acatgttgaa agtcacaatg ctcaacaaac
     2101 agacgcaaac ttctttacag aattccttga gaaatgggat cgtggagaat accacgacta
     2161 agaggtgacc tatgatttta acagtcacaa tgaacccatc catcgatatt tcctatccct
     2221 tggatgagtt gaagattgat actatcaatc gtgtggtgga tgtaaccaaa acggctggtg
     2281 gtaagggact caatgttacc cgagtacttt cagaatttgg cgattctgtt cttgctactg
     2341 gtttagtggg tggcaaactt ggtgagtttt tggttgaaca tatcgataat caagtaaaga
     2401 aagatttctt ctcaattaag ggagaaactc gtaactgtat cgctattctc cacggagaca
     2461 accaaacaga agttcttgaa aaaggtcctg aagtattgga acaggaaggt caagagtttt
     2521 tggaacattt caaaaaactc ttggagtcag ttgaagtagt agccatctca ggtagtctgc
     2581 cagctggcct tccagttgat tactatgcga gcttggtaga acttgctaat caagctggca
     2641 agcctgtagt cttggactgc tcaggtgcag cacttcaggc tgttcttgaa tcaccccata
     2701 aaccaacagt catcaaacca aataatgaag aattgtctca gcttcttgga agagaagttt
     2761 ctgaggattt ggatgaatta aaagaagtac ttcaagaacc tttgtttgca gggattgaat
     2821 ggattatcgt ttcacttggt gccaacggta cttttgccaa acatggtgac actttctaca
     2881 aggtagatat tcctagaatt caggtggtaa atcctgttgg atctggagac tctactgtgg
     2941 caggaatttc ttcaggactt cttcacaaag aatcggatgc agaattactc atcaaggcaa
     3001 atgtccttgg tatgctcaat gctcaagaaa aaatgactgg tcatgtcaac atggccaact
     3061 atcaagctct atatgatcaa ttaatagtaa aagaggtata aaatggcttt aacagaacaa
     3121 aaacatgtac gcttagaaaa actttctgat gaaaatggta tcatctcagc tcttgcattt
     3181 gaccaacgtg gtgctttgaa acgcctcatg gctcaacacc aaacagaaga accaactgtg
     3241 gcccaaatgg aagaacttaa agtcttggta gcagatgaat tgactaaata tgcttcatct
     3301 atgcttcttg accctgagta tggacttcca gcaactaaag ctcttgatga aaaagctggt
     3361 cttctccttg cttatgaaaa aacaggttat gacacaacaa gcacaaaacg cttgccagac
     3421 tgcttggatg tttggtctgc aaaacgtatt aaagaagaag gtgcagatgc agttaaattc
     3481 ttgctttact atgatgtaga tagctcagac gaactcaatc aagaaaaaca agcctacatc
     3541 gaacgcatcg gttctgagtg tgtggctgaa gatatcccat tcttccttga aatccttgct
     3601 tacgatgaaa aaattgcgga tgcaggttct gtagaatacg ctaaagtaaa accacacaaa
     3661 gttatcggcg ctatgaaagt cttttcagac ccacgcttta acattgatgt tttgaaagtt
     3721 gaagttcctg ttaacattaa atatgttgaa ggcttcgctg aaggtgaagt agtttataca
     3781 cgtgaagaag cagcagcctt cttcaaagcg caagatgaag caacgaactt gccatacatc
     3841 tacttgagtg ctggtgtatc agctaaactc ttccaagata ctcttgtatt tgctcatgaa
     3901 tcaggtgcaa actttaacgg agttctttgt ggccgtgcta catgggcagg atcagttgaa
     3961 gcttacatca aagatggtga agcagcagct cgcgaatggc ttcgcacaac tggatttgaa
     4021 aacattgacg aactcaacaa agttcttcaa agaacagcaa cttcatggaa agaacgcgtg
     4081 taagaaagtc ctcctagttt aggaacatga atctaaaaaa atttaaaaaa agttgtatgt
     4141 aaaggtttac aaaataactt acttgtgcta tacttaaatc acaagttaat atgaattaga
     4201 aagtaactat atgaagtata ataaaaatag gatatagttt attttacgag ctaggaagga
     4261 aaaaatacgg aaacaatatt gccagaataa actatattta gatgcacatt tcactcattg
     4321 ttttataaaa ggagaagata aatggctact aaaaagagtt ttaaagcgtt agttgtagga
     4381 ctaggtattg tttcaatatt ctcatcagcc ttacctatgg ttagtggttc tgtatttgca
     4441 gatagtgccc taactacagt agataaagca aatgatattg ttttgaatgt tgatgggaat
     4501 aaattttata atgtttcggt ttcagaagat attgtaaatg ctggtcaaat tttggaagat
     4561 tatttttatg tagataaatt tggaaatata aatttaaaag gcactcctga agagttatca
     4621 aaaaatattg gtatttctgt acaagaagca agtttgatgt atgaagctgt aaaagagttg
     4681 cccaacgttt acgaaagagg tcctgtaggt tttcgtttca atcttggtcc tcaagtgagg
     4741 gggatgggtg gctgggctgc tggagctttc gctactggat atgctggatg gcatttgaaa
     4801 caatttgcgg ttaatcctgt tacatctgga tttgttgctg taataagtgg tgcgattggc
     4861 tgggctgtaa aaactgctgt agaaaattat tggacagttg ctgtagctac agtagaagtg
     4921 ccgtttgtga accttgttta caccatagat ttaccttaga ggttatttct ttatgaatca
     4981 ttcttttaaa aaaataactg tattttgttt tatagtttct tgtgttcttt gtttattaga
     5041 cttaatgaat tttaaaaatg tagctacttt tttatttttc tgtcttcctg tttttgtttt
     5101 gatttacaaa aataaataaa aacagagcct ctgtttgatg aattttagaa catagttaag
     5161 ttttaaaaaa agttgtatgt aaaggtttac aaaacaaccg acttgtgcta tacttaaatc
     5221 acaagttaat acaaggtgag tgttactaag taatattagg catgatcaca ggtgaattag
     5281 aaatcagctg attttctagt tcatttgtgg tcattttttg tactcatata cctttaagat
     5341 ataaaaggag gttgacatgt atcgaattct aaatccaatg aatcacaatg tctcgcttgt
     5401 cagaaatgat aagggagaag aggtgattat aattggtaag gggattgcat tcggaaaaag
     5461 gaagggggat ttgattgctg aaaatcaggt tgagaaaatc tttcggatga agaccgaaga
     5521 gtccagagaa aactttatgg ctcttctcaa agatgttccg cttgatttta tcacagtgac
     5581 ctatgaaatc attgataagc tatcaaagaa atatcattat ccgattcaag agtatctcta
     5641 tgtaaccttg acagatcata tttactgttc ttatcaagct ctaactcaag gaaggtacaa
     5701 ggatagtaat ctgccggata tttccgctaa gtatcctgtc gcttttcaaa tcgcaaatga
     5761 agcttttgaa atttaccgtc agaagctagc agatcatttt cctgaggacg agattattcg
     5821 gattgcttat catttcatca atgccgaagg tgaaaatgaa gtggaacttg tggagtcgat
     5881 tgataagagg aaagaaattc tcaggaatgt tgaagaagtg ctaaagggtt atgcaattca
     5941 acgaaccaaa aaaaataatc atttctatga tcgctttatg attcatttga attatttctt
     6001 ggattattta gacagatcta gagatgataa ccaatcactt ctggatatgg aagatcatat
     6061 taaacaatcc tatccaaaag ccttcgagat tggttccaag atctatgatg tgattacgca
     6121 acatacgggt cttgatttgt ataaaagtga acgagtttat ctagttctac atatccaacg
     6181 tttattgtca taaaaattta tttaaaacta tataaggaga attctatcat gaatagagaa
     6241 gaagtaacat tgttaggttt tgaaatcgta gcctatgctg gcgatgctcg ttcaaaacta
     6301 ttggaagcct tgaaggctgc tgaagctggt gattttgaaa aagcggacgc tctggtagag
     6361 gaagctggta gctgtattgc agaggctcac cacgcgcaaa caagtctatt gactaaggaa
     6421 gcttctggtg aggacttagc gtatagtgtg accatgatgc atggccaaga ccacttgatg
     6481 acaactatct tgttaaagga tttgatgcac catttgatcg aactctataa gagaggagtt
     6541 aaataatgaa caaactaatt gcatttatcg agaaaggaaa gcctttcttt gagaaactat
     6601 ctcgtaatat ctatcttcgt gctattcgtg atggtttcat tgcaggtatg cctgttattc
     6661 tcttctcaag tatctttatc ttgattgcct ttgtaccaaa ctcatggggc tttaaatggt
     6721 ctgatgaagt tgtagccttt ctgatgaaac cttatagcta ttctatgggt attctggctc
     6781 tcttggtagc tggtacaaca gctaagtcat tgaccgactc agtaaaccgt agcatggaga
     6841 aaaccaatca aatcaactat atgtcaacgc tgttagcagc gattgttggt ttgttgatgt
     6901 tggcagctga tcctatcgaa aatggtctag ctactggatt cttggggaca aaaggtttgc
     6961 tttcagcctt ccttgctgcc tttgttactg tagccatcta taaggtctgt gttaagaaca
     7021 acgtcactat tcgtatgcct gacgaagttc caccaaatat ctcacaagtc tttaaagatg
     7081 tgattccatt cactctatca gtggtttctc tttatgctct tgatttacta gctcgtcatt
     7141 ttgttggttc tagtgtggca gaatcaatcg gtaaattctt cgcaccactc ttctcagcag
     7201 cagacggata ccttggtatt accattatct ttggtgcctt tgccttcttc tggtttgtgg
     7261 gtattcatgg tccatctatt gttgaacctg ctatcgcagc gattacctat gcaaatgctg
     7321 aagtcaactt gaaccttctc caacaaggta tgcatgctga taaaatcctt acttcaggaa
     7381 ctcaaatgtt tatcgttact atgggaggta ctggtgcgac actggttgtt ccattcatgt
     7441 tcatgtggtt aacaaaatca aaacgtaacc gtgcaatcgg acgtgcttca gtagttccaa
     7501 ctttctttgg tgtaaatgaa ccaatcttgt ttggtgcacc acttgtatta aatccaatct
     7561 tcttcattcc atttatcttt gctccaatcg caaacgtatg gattttcaaa ttctttattg
     7621 aaactcttgg aatgaactca ttcactgcta atctaccatg gacaactcca gctccactag
     7681 gtctagttct tggaactaac ttccaagtgc tatcattcat tcttgctgcc cttctaatcg
     7741 tggttgacgt tgtcatttac tatccattcc ttaaggtcta tgatgaacaa attcttgaag
     7801 aagaacgttc aggtaagtct aatgatgaat tgaaagaaaa agttgctgca aacttcaaca
     7861 ctgcaaaagc ggatgctatt cttgaaaaag cgggtgtaga agcagcacaa aatacaatca
     7921 ctaaagaaac aaatgtcctc gttctctgtg caggtggagg aacaagtggt ctccttgcaa
     7981 atgctttgaa taaggcagca gcagaataca atgtccctgt gaaagcagca gcaggcggct
     8041 atggtgctca ccgtgaaatg ttaccagagt ttgatcttgt tgtccttgcc cctcaagttg
     8101 cttcaaactt tgaagatatg aaagcagaaa cagataagct cggtattaaa ctagcgaaaa
     8161 cagaaggcgc tcaatacatc aaattaactc gtgatggaaa aggtgcccta gcattcgtac
     8221 aagcgcaatt cgattaaggc tagagactct gaaattgtct cctatcgtta cggaaatcgc
     8281 tatggcgaat ttcctaatcg ccttattaat tcggtgactt ggtacaagaa gtgagatgga
     8341 gaaggatggc tcactgactc ccctcctctc acttttactt tatttaaatc aagaaatagg
     8401 tgaaaaaaat gacaaaaaca cttccaaaag actttatttt tggtggcgca acagctgcct
     8461 atcaagcaga aggtgctaca catactgatg gtaaaggacc agtagcgtgg gataaatatc
     8521 ttgaagataa ctactggtac actgcagaac cagccagtga tttttacaat cgatatccag
     8581 ttgacctcaa gctagcagaa gagtatggtg tcaatggcat tcgaatttct attgcctggt
     8641 cacgtatttt cccgactggt tatggtcaag taaatgctaa aggtgttgag ttttatcata
     8701 atctatttgc ggagtgccac aaacgtcatg ttgagccctt tgtaactctt catcactttg
     8761 acactccaga agctctccac tcaaatggag acttcttaaa ccgtgaaaac attgaacact
     8821 ttgtagacta cgcggctttc tgttttgaag aatttccaga agtaaactat tggacaacct
     8881 tcaatgaaat tggaccaatc ggtgatggtc aatatttagt tggtaaattc cctccaggaa
     8941 ttcagtacga ccttgccaaa gtcttccaat cgcaccacaa tatgatggtg tctcatgcac
     9001 gtgctgtaaa gctatataaa gataaaggat ataaagggga aattggtgtt gttcacgccc
     9061 tgcctactaa atatcctcta gatcatgaaa atccagcaga tgttcgtgca gctgagttgg
     9121 aagatatcat ccacaataaa tttattttgg atgcaaccta tctgggtcac tactctgaaa
     9181 agactctggc aggggtagag gctatcttat cagtcaatgg tggtagtttg gatcttcgtg
     9241 aagaagattt tacagcatta gaagctgcaa aagacttgaa tgatttccta ggaatcaact
     9301 actatatgag tgactggatg gaagcctttg atggagaaac tgaaattatc cataatggta
     9361 aaggtaaaaa aggaagctct aagtatcaaa tcaaaggtgt tggtcgtcgt gtagctcctg
     9421 actatgtacc acgcacggat tgggattgga ttatctaccc tcaaggtttg tatgaccaaa
     9481 tcatgcgtgt gaagaaagat tatcctaact acaagaagat ttacatcact gaaaatggtc
     9541 tcggctataa agatgagttc gttgataaca ctgtttacga tgatggtcgt attgattacg
     9601 tgaaacaaca cttggagatc ttgtctgatg cgattgcaga tggagctaat gtaaaaggtt
     9661 acttcatttg gtcattaatg gatgtcttct catggtcaaa cggttatgag aaacgttatg
     9721 gtctcttcta tgtagacttt gaaactcaag aacgttatcc taagaaatca gctcactggt
     9781 acaagaaagt agcggaaact caagtaattg agtagtagaa ttagtaatta gatatagaat
     9841 tttagtgagg caaaaagatg ttcaaagatt ttatccaatc tatttatgaa aaagtttata
     9901 ttatcaattt tgataaatgt tctcaaatac cgtgtttgac gaatgaagaa ctgaaaagtc
     9961 tcggaaaatg gtatgtctat accggtaaag aatggatttg ccattcagac tatgagctgg
    10021 aagaatttaa aaatatcttt ttaaatttta tcaatcctga agaatgggat actatctcct
    10081 ttgattcaga ttttatgccg ttttaacaat cgtaaccaat ttccaaaaaa gttaaatctc
    10141 gtatttagta cgctgcaaaa ctcttatcta atcacgttgc ttatactcaa tgaaaatcaa
    10201 agagcaactt taaactagaa agcgagtcgc aggtttctca atgcatcgct ttgaggttgc
    10261 agataaagca attaggcaaa aagtctttaa cgcagaaaaa cgcataatat caggtttaaa
    10321 aaaccttgat actatgcgtt ttattgtggg aagatttact tctgaaattg agttgttacc
    10381 cagaatcttt cagtttatta aggcttgatg actttagtaa gtttagatag ttcaaaaagg
    10441 attgaatcac ttagtttaga atctgaaaca atagtatcaa gatttgatac attataaaaa
    10501 gtataaaaat caaacttatt gaacttacta tgatctgcga gtaaatattt tttattagaa
    10561 ttatttaaag cgatgcgttg agcctctccc tcttcctcgc taaaagtagc tagagctccg
    10621 ttttgaatac cattacagct aacgaaagct ttagaaaatt ggagattaga gagattttgt
    10681 agggtcaatg tgccaacaaa agcacctgta atatcgcgat aatttccacc tatcaaaatc
    10741 aaatctgtta attttcgttc gcttaaaatc agaaaaacag gtagactgtt ggtcacgacg
    10801 cggatattgt caataggcaa ctcacgcgca aaaaattcta atgttgttcc tggtccaatg
    10861 aaaatagttt ctctttcttc tactagactg cctgcaaaac gggctatttc ttgtttttct
    10921 gccgtttgga gggcttgttt ttcaatattt gatcgctcat tagtcaaaag ggagttggtt
    10981 cgaagttttt cagctccacc atgcacacga atcagcaaat ctttatcagc taattcctgt
    11041 aaatagcgcc ttgcagtcat atctgaaacg gctatttcgt ccataatctg tttaaccgtt
    11101 atggttcctt tactatttac tatctctaaa attttggtta atttttcttg tttgagcata
    11161 ttatcacctc gtttcctact actatcttac cataaactag ctcatcattc aaatacaaaa
    11221 acaacaaaat aaaacaaaaa caaaaatatc gaggtttatt ttcaaaactt tcgatatttt
    11281 tattaagtta ttattttgtt gtttctagtt tactttttga tgattgagag tggtggagaa
    11341 ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgtaggttg ctcaaaacac
    11401 agttttgagg ttctagataa gactgatgaa gtcagtgagc atatctacgg caaggcgaag
    11461 ctgacgtggt ttgaagagat tttcgaagag tattagtcca aaccgtagtt gtagtcattg
    11521 tcttgcatgg cttcaacttc accaaggagg taaccatttc cgacttgaga gaagaagtcg
    11581 tggttagatg ttcctgttga aataccgttc ataacgattg gattgacatc atctgctgaa
    11641 tctgggaaga gtggatcttg tcccaggttc atgagagcct tgttagcatt gtagcgaagg
    11701 aaggttttga cttcttccgt ccaaccaaca ccgtcataga ggctttctgt gtagccttct
    11761 tcattttcat aaagagtata gagcaggtcg tacatccatt ctttgagttt ttcttgctct
    11821 tcttcaggta attcattgaa accaagttgg aatttgtaac caatgtaagt tccgtgaaca
    11881 gactcatcac gaataatcaa tttgatgatt tccgcaacgt tggccaactt gttatttcct
    11941 agatagtaga ggggagtgaa gaaacctgaa tagaagagga aggtttcgag gaagacactg
    12001 gcaactttct tttcaagtgg gctaccgttt aggtagattt cgttgacaat ctcagccttc
    12061 ttttgcagat aaggattggt attggtccat tcgaaaattt cttcaatctc agccttagta
    12121 tttaaggtag aaaagattga tgagtaagat ttagcatgga cagattccat aaattggatg
    12181 ttattgaaaa cagcttcttc atgtggtgta cggatgtctg cgcgaagggc ttgaaccccc
    12241 gtttcagatt gcatagtgtc aagaagggtt aaaccaccaa aaacttttcc gaccaagtct
    12301 ttctctttgt ttgatagttt tctccagtca tccaagtcat ttgacaaagg aatacgtgta
    12361 tcgagccaga attgctccgt cagtttttcc caagttgatt tgtcgatgac atcttcgatg
    12421 gcattccagt taatggcttt gtagtaagtt tccatttgaa atctctttct gtgtatagta
    12481 ttgtgaactc acaattattt ttattttatc ataattccag aggaatatcg cacaaaaagt
    12541 cggagaaccg acttttgaaa tgttacataa attatgttat gacatagtag atttgatttt
    12601 atcagtgctg cttagggaaa aatagtgttt ctctgctaga aactaaatca cacagctttc
    12661 acactggttg gcaccgactt ctccaccgtc gtctgtaaag gtacggacgt agtagataga
    12721 cttgataccc ttgttaaagg catagttacg aaggatagat aagtcacgtg tcgtttgttt
    12781 gttttctttc ttccattcat aaagaccttt tggaatatca ctacgcatga agagagtaag
    12841 tgaaagtcct tgatccacgt gctccgttgc agcagcgtat acatcgatga ctttacgcat
    12901 atccatgtcg taggcagaag tgtagtaagg aatggtttct gttgacaagc cagcagcagg
    12961 atagtagatt ttaccgattt tcttttcttg gcgttcttcg atacgttgcg taattgggtg
    13021 gatagaagca gaaacgtcat tgatgtaact gatagaacca tttggcgcta cagcaaggcg
    13081 gttttggtgg taaagaccat ctgcttgaac cttgtcgcga agttcagccc aatcagcagc
    13141 acttgggata aagacatctt tgaagagttc tttaacacgt tctgattttg gaacaaactc
    13201 gcctgtaata tacttgtcaa agtagcttcc cttagcatag tctgattttt caaagttgtg
    13261 gaaggtgata ccacgttcac gcgcgatatt gtttgactca accaaggtcc agtagttcat
    13321 aagcataaag tagatgcttg tgaattcaac agactcaggc gatccatatt caatgagttg
    13381 ttgggcaagg tagctatgaa gtcccatggc accgagacca aaggtgtggg cttggctatt
    13441 tccatggtca atcgtaggta cagctacgat gtgtgaacta tctgtaacga aagtcaaagc
    13501 acgaaccatg gcacggatag aacgaccaaa gtcaggtgaa gtcatcatgt tgaccacgtt
    13561 ggttgaacca aggttacatg aaacatccgt tcccatttga aggaattctt gagcatcgtt
    13621 gatcaagctt ggttcttgga cttgaagaat ctcagaacac aagttactca taataatctt
    13681 tccatcaaca ggatttgcac ggttagccgt atcaatgttg actacataag gatagccaga
    13741 ctcttgttgc aatttagaga tttcagtttc caaatcacgc gccttgattt ttgtcttgcg
    13801 aatatttgga tttgcgacca attcatcgta tttttcagtg atgtcaatgt agttgaatgg
    13861 cacaccgtat tctttttcta cagagtaagg actgaagagg tacatttctt catttttacg
    13921 agccaattcg tagaatttat ctggtactac aacaccaagt gatagggttt tgacacgaac
    13981 tttttcgtcg gcgttttctt tcttagttga aaggaaggcg atgatatctg ggtgaaagac
    14041 attgaggtag acaaccccag caccttgacg ttgccccaat tggttggagt aagagaaact
    14101 gtcttcgaaa agcttcataa caggaacgac acctgaagct gctccttcat aacccttgat
    14161 aggtgcacca gcttcacgaa ggttgctgag ggtaattccc acaccaccac cgatacgtga
    14221 aagttgaagg gcagagttga tagaacgtcc gatagagttc atatcatccg tcacttggat
    14281 taggaaacaa gataccaact ccccacgacg agcacgtcca gcattcaaga aggaaggagt
    14341 agcaggttgg tagcgttggt ggatgatttc attggcaata tcgattgcaa cagcttcatt
    14401 cccatcagcg aaataaaggg cgttaaagaa gacacggtct tccatacttt caagatagta
    14461 ttcaccgtca ttagccttta aggcatattg attgtaaaat ttataggcag ccatgaaaga
    14521 cttgaattgg aagttttggt ctttgataaa ttgagccaat tcttccaaga actctggacg
    14581 gtatttcttg ataaaggctg tttcgatgta gttgtgttca atgaggtaat tgattttgtc
    14641 tttgattgaa tcaaaaacca tagtgtttgg aactacattt tctttaaaga aagcatccaa
    14701 ggcttcctta tctttatgaa gcatgatttg tccattaaca ggacggttga tttcgttatt
    14761 aagacggaag taagtcacgt cttcaagatg ttttaatccc ataaaatttc ccttatctaa
    14821 ttacaaaaga aaggcttcta agttagccct aaaagcagtt tcttctggat gatgtactaa
    14881 gattatgcta attgtttcag ttttcctggt tggaaacctg aaaagacttc agttggtgtt
    14941 tggataacag gagctgcgct aaaaccgagc tctttaactt gatcgacgta ctcaggttgc
    15001 tcatcaagat tgatttcacg ataagagaca ttattactgt ccaagaaacg cttggtcatt
    15061 ttacattgga cacaattgtt tttagaataa acggttacca ttgtgtaact cctcttcaaa
    15121 atttaatact atcttagtat atcagaaaat aaaattttgt caatgatttg aactaaatat
    15181 agtggtgttc ttttgttgtt tttatataca aacacaatat atagtgtttg cgttgtgaat
    15241 agcaatgatt atcctataaa ttgtttttga agaaactata tcctgtgttt tgttatctag
    15301 gatagaagat tttcagcaag ttatctgaaa ggaaattgaa ggaaaatcca gaaaatgctt
    15361 gaaaaaaatc ctagaagatg gtataatacc aaattgtaag ggttatcaca tataactcaa
    15421 aaaaagaaag aacaaaagga gagtcaaact atggcttcta aagatttcca cgtagtggca
    15481 gaaacaggta ttcacgcacg tccagcaaca ttgttggtac aaactgctag caaatttgct
    15541 tcagatatca ctcttgagta caaaggtaaa tcagttaacc ttaaatcaat tatgggtgtt
    15601 atgagtcttg gtgttggtca aggtgctgac gtaactatct cagctgaagg tgcagatgca
    15661 gatgacgcta tcgctgcaat ctcagaaaca atggaaaaag aaggattggc ataagggaaa
    15721 tgacagaaat gcttaaagga atcgcagcat ctgacggtgt tgcagttgca aaagcatatc
    15781 tactcgttca gccggatttg tcatttgaga ctattacagt cgaagataca aacgcagaag
    15841 aagctcgcct tgatgccgct ctacaggcat cacaagacga gctttctgtt attcgcgaga
    15901 aagcagtagg tacgctcggt gaagaagcag ctcaagtttt tgatgctcac ttaatggttc
    15961 ttgctgaccc agaaatgatc agccaaatca aggaaactat ccgtgcgaag aaagtgaatg
    16021 cagaagcagg tctgaaagaa gttacagata tgtttatcac tatctttgaa ggcatggaag
    16081 acaacccata catgcaagaa cgcgcagcgg atatccgcga cgtgacaaaa cgtgtattgg
    16141 caaaccttct tggtaaaaaa ttaccaaacc cagcttctat caatgaagaa gtgattgtga
    16201 ttgcacatga cttgacacca tctgatacag ctcaattgga caaaaatttt gtaaaagctt
    16261 ttgtaaccaa catcggtgga cgtacaagcc actcagctat catggcacgt acacttgaaa
    16321 ttgcagctgt attaggtaca aacaacatca ctgaaatcgt taaagacggt gacatccttg
    16381 ctgttaacgg gatcactggt gaggttatta tcaacccaac tgatgaacaa gcggcagaat
    16441 ttaaagcagc tggtgaagct tatgcgaaac aaaaagctga atgggcgctc ttgaaagatg
    16501 ctcaaacagt gactgctgac ggtaaacact tcgagttggc tgctaatatc ggtactccaa
    16561 aagacgttga aggtgttaac aacaacggtg cagaagctgt tggactttac cgtacagagt
    16621 tcttgtacat ggattctcaa gacttcccaa ctgaagatga gcagtatgaa gcatacaagg
    16681 ctgttcttga aggaatgaac ggtaaacctg ttgtcgttcg tacaatggat atcggtggag
    16741 ataaggaact tccttacttc gatatgcctc acgaaatgaa cccattcctt ggattccgtg
    16801 ctcttcgtat ctctatctct gagactggag atgctatgtt ccgcacacaa atccgtgctc
    16861 ttcttcgtgc gtctgttcac ggtcaattgc gtatcatgtt cccaatggtt gcgctcttga
    16921 aagaattccg tgcagcgaaa gcagtcttta atgaagaaaa agcaaacctt cttgctgaag
    16981 gtgttgcagt tgcggataac atccaagttg gtatcatgat cgagattcct gcagcggcta
    17041 tgcttgcaga ccaatttgct aaagaagttg acttcttctc aattggtaca aacgacttga
    17101 tccaatatac aatggcagca gaccgtatga acgaacaagt ttcatacctt taccaaccat
    17161 acaacccatc aatccttcgc ttgattaaca acgttattaa ggcagctcac gctgaaggta
    17221 aatgggctgg tatgtgtggt gagatggctg gtgaccaaac agctgttcca cttcttgtcg
    17281 gaatgggctt ggatgagttc tctatgtcag caacatctgt ccttcgtaca cgtagcttga
    17341 tgaagaaatt agatactgct aagatggaag agtacgctaa ccgtgccctt acagagtgtt
    17401 caacaatgga agaagtcctt gaacttcaaa aagaatacgt taatttcgat taatgtcatt
    17461 aaccttgtaa cctagttgca aggttttttt gacgcatttt ggaaaagtat ggtcttataa
    17521 agtccacttt tcaatgagtc agaggcatga tataataggg ggaaacaaat agaataagag
    17581 agaaaccatg tctaaagaaa ttgatattga gtattaccat cagctagcct tgcaaaagca
    17641 gaaggagcat cgaaaagttt tagccaatct aaagaaaaaa cctcctaaaa acctagacaa
    17701 gatagcccag cagattcacc aagaagtctt tgaggagatt gattgtaccg cctgtgctaa
    17761 ctgttgcaag acattgggac ctgactttaa agaagcggat attactcgta ttgccaagta
    17821 ttttaagatg aaattaccag cttttgaagc ggagtttctg caggtagatg aagatgggga
    17881 caaggttttc aaatccatgc cttgcccatt tttaggagga gataatctct gctctatcta
    17941 tgatgttcgt ccaaaggcct gtcgtgaatt ccctcatact gaccgcaaaa agatccatca
    18001 aatcaaccat ctgacgatta agaatacctt gacctgtcca gcggcctatc tctttgtgga
    18061 gaaattaaag gataagttgt agagatttaa aggataaaaa atctctaata ataactaggg
    18121 atatgaaagg agtactccta tgcctagacc aaaaacaaaa gaggagctag tgctagcctc
    18181 taaggaaaac tatgacaagc tcaaccgttt catctcccaa ctaagtgaag atgagctaca
    18241 gactccattt gatttttcaa aagaccaaaa gaaaaaggaa gcgcactgga aaagagataa
    18301 aaatctaaga gatgttctga tccatctcta tgaatggcag cagttacttt tgacttgggt
    18361 acattctaat caaaaggggc atgagagacc ttttctccct gaaccttata attggaaaac
    18421 ttatgggaag atgaatgtca ctatttggaa aaagcaccag aaaacctcct tagaagaagc
    18481 gactagactc ctagaacaat cacatagaga ggttttagag ttgatggaag gcttcagcaa
    18541 tgacgaactc tttgccaaag gtatctataa gtggacggga ggaacaagtc taggttccta
    18601 ctttgtcagt agcacctcca gtcactatga ttgggctcta aaaaagatca aagcacatca
    18661 gaagaattgt aaaatgcaga tggactcttt gaaaaagaat gaattctttt aaacatgaga
    18721 taagattaaa agggctatca agtgacgtag cccttttgag ttatagaata gaattaccat
    18781 gcaaaagctg tcgttggagc attgagcgct tttaaccatt gtttattttt tacagggcaa
    18841 agagttacgg atatacctgc catatccaga ctggtcataa atgttcctga ttttataaag
    18901 gtaatagtga ctccttcaat ttctaagagt tgaaggatat cattgataaa tatgcccatt
    18961 tctaggttgc tagtagtgcc tagattattt acaagcaata taaattgatc accctttttc
    19021 caatgatagt gcaatcttaa tttgcttata atttcatttg ccaggatttc cgatgattga
    19081 aatgggacaa tacgataacc ttcttcaccg tgtatcccaa taccatagga aatatttcct
    19141 tcttccaagt taaatagtgg aagggtggct tgagggaggc tagcagattt cgttgcaaag
    19201 ccaattgttg cgatttcggg agcaagttca tgacctaaat cagttagttg ctcgatgtcg
    19261 gcaccatttt gagctgcata tcctagaact ttatgaagta aaatagtccc tgcaagccct
    19321 cttcctctaa tttgaaatct attgtgaggt tcaatagaaa tatcgtcgtg tgctagacta
    19381 tagccgacct taattccttc ttgtctagca gtattaatgg cccagctaaa ttctttgatg
    19441 tctgcttcga aattttttac aatgatgaag acaccgtgac cattgtttaa aaaacgaatg
    19501 gactctaaga tttcagttct tgtaggagga gtaaataatt ggccatagat agcagcggta
    19561 agcatgcctt ctcccacata tccaatatgc gcaggttcgt gaccggaacc tccacccgac
    19621 aatattggaa cctgatgagg attgcgattt ttttgataga ctagtggtaa agtagggtgt
    19681 ttttctaatt caggatgact gctgacagtt gctgaaatgt aacttgaaat aattttttgt
    19741 ttatgatttg aaataaatgt cattgtggtc tctttccaat aattgtcatg attagaaagt
    19801 ctggttgtgg aactggactt tttttattga cgtaagcctt cacgatttct gctagagcat
    19861 gtgaatgata gtctaacaaa aaacaagtat aggcagatga atcgatatca atctgaccat
    19921 attctcttaa aatttttgat acaagcaagc gacagtagct gataaattgg tcatagaagt
    19981 tattttgccc ttgaatatca aaaagttgaa tataaaagtc acgctcttgt tcgaaataaa
    20041 gaaataattc ttgtaatagt ttttggcccg aaatgaagtc caagttattg gtaatatact
    20101 cggttaagtc agtttcaaaa atccagtcta gcagttcata tttgtcaaga aagtgattgt
    20161 aaaaggtctg tctacgaatg ccagctgatt ccatgatatc tacaatagag attttgtcaa
    20221 attctctagt agctaatagg tctctaaatg ccttggcaat ccgttttttt gtaatgagtg
    20281 atgatgccat aggaagcctt tcttttactt acttcatttt accaaaaaaa tgttttaaac
    20341 gggtttaaaa ggggacaaat aatagaatct gtcccttatc atccagcaat aaaaaatata
    20401 taatgaaagc gaaaacaaaa gtaaatgccg aaaggagttt ctcatgaaaa aaattataaa
    20461 taaaccgaca caagttgttg atgaaatgtt gcaaggattg tcattcatgc atgatgactt
    20521 ggtagaacgc ttagatggtt ttgatgtcat cgttagaaag gtagaaaaga caggaaaagt
    20581 tggactcatt tcaggtggag gttcaggaca tgaaccaagt catgctggat ttgtaggaga
    20641 tggaatgttg tctgctgcca tttgtggagc agtcttcact tcacctactc cggaccaaat
    20701 tttagaagcc atcaaggcgg ctgatgaagg tgctggagtt ttcatggtca tcaagaacta
    20761 ttctggtgac attatgaact ttgaaattgc acaagaactt gctgaaatgg aaggtattga
    20821 tgtagcaagc gttgtggttg atgatgatat cgctgttgaa aatagtctct atacccaagg
    20881 gcgtcgaggt gttgcaggta ctatattagt ccataaaatt ttgggggctg cagctcgttc
    20941 tggtaaatca ttatctgaaa tgaaggactt ggccgataaa cttgtcttag aaattaaaac
    21001 aattgggcta gccctgtctg gagcaaccgt tcctgaggtt gggaaaccag gatttattct
    21061 ggaagatgat gaatttgaat atggagttgg tattcatggt gagccaggat ataagaaaga
    21121 gaaaatgcaa ccttcagcac aattagcctc agaattggtt gaaaaactat ctgaaggttt
    21181 ccaacttaaa gctggtgaac gctatgggct tctcatcaat ggtttaggaa gcacccctct
    21241 tatggagcaa tacgtatttg caaatgatgt ggctaaatta ctccatgaaa aaggtgttga
    21301 gttgtcattt aagaaaattg ggaactatat gacctcaatc gatatggctg gcttgtcatt
    21361 gacattgatt cgattggcaa atgatgaatg gttggatgct ctaaatgcac ctgttactac
    21421 accagcttgg taaaactcaa ggaggaaatg tcgcataaat gctgaacaag cacttgaatg
    21481 gatgaagctt tttaatgaaa agattcaaga acagaaagat taccttagtg agttagacac
    21541 tcctataggg gatggagacc acggtggaaa tatggcgcgt ggaatggctg cagttatgga
    21601 aaatttagaa ggaaagcaat ttgagacaag cagtgatgtg tttaaagttg tttcaatgca
    21661 actactgagt aaggtaggcg gtgcttctgg tcccttgtat ggctctgctt ttatgggaat
    21721 gtccaaggct gattctcatt caaaattaga agaaatctta caaagtggtt tggatatgat
    21781 tgtcaaacgt gagaaagcag tagttggaga gaagacaatg gttgatgttt ggactcctgc
    21841 tattgctgcc ttgtctgatg gccaattgac tcatgagctt attgataagg tagtgaatgc
    21901 taccaaagat ttacttgcaa ctaaaggaag agcatcttat gtaggagaac gttctcttgg
    21961 acatattgat cctggatcat tctcatcagg attactcttt actgctattt tagaaactgg
    22021 ggtggtttga tggaaagtat tggtcttgtt atcgtttcac attccaaaaa cattgcagaa
    22081 ggtcttgttg aactgattag tgaagtagct aaagatgttc caattactta tgtaggagga
    22141 accgaagatg gaggaattgg aacaagtttt gatcaagtag atagggttgt ttccgaaaat
    22201 ccagcagata ctttattagc cttttttgac ctaggttctg ctaaaatgaa cttagaaatg
    22261 gtggctgatt tcagtgataa aagtatcatg atcaataggg ttccaattgt agaaggtgct
    22321 tatactgcag ctgctcttct tcaggctggt gcagaactgt cagttattca aacacagttg
    22381 tcggagcttg aaatcaataa ataaggaatt ttactataac actttttata ggtgggctat
    22441 tgattatctc aactatcaaa ttttaagtaa ataaaaaggg attgctttgg gcagttcctt
    22501 tttattttaa caagagtaaa cctatagtgt ttctaaattg tgaatcattc aaaactgatt
    22561 gtgatgagac tattctagct ttagaatcct tcaaaaatta aagtttaagg caatcaatta
    22621 cttagaagag tacgaaaaca tttagtttat aggaattcta ggtttagaat cacatggata
    22681 tttattaagt cagggtgttc gatagttagg attgttctat tctgaaagat ttgagctgtc
    22741 aattgtatag gatagtgttc gaattttttt caagtgatta aattagttaa ttgtatgagg
    22801 tgctttatga tataatgttc ttaatgaatt ttcagaaagg aaaacctcaa attgtcctac
    22861 aaatttctac tcttcgacct cgaccacact cttcttgatt ttgatgctgc tgaggatgtg
    22921 gctttgaccc aacttctaaa agaagaagga gttgcggata ttcaggctta taaagattat
    22981 tacgttccta tgaacaaggc tctctggaaa gacttggagc tgaagaaaat cagtaaacaa
    23041 gagctggtta acacgcgctt ttctcgttta ttttctcatt ttggacaggg aaaagatggt
    23101 agttttcttg cccaacgtta ccaattttac ctcgcccagc agggacaaac actatcgggc
    23161 gctcatgatc tcttggacag cctcattgat cgtgattatg acttgtatgc tgcgacaaat
    23221 ggcattactg ccattcagac aggacgtttg gctcaatctg gtctagaacc ttatttcaat
    23281 caagtcttta tctctgagca attgcaaact caaaagcctg atgctctatt ttatgaaaaa
    23341 atcggtcagc agattgctgg ctttagcaaa gaaaagacgc tgatgattgg agattctcta
    23401 accgccgaca ttcaaggtgg caataatgct ggaattgaca cgatctggta caaccctcat
    23461 cacctcgaaa atcacacaca agcccagcca acttacgaag tccattctta ccaagacttg
    23521 ctggattgtt tggataaaaa tattcttgaa aagattacat tttaaaggat acgagctaat
    23581 gactacaaaa aaagctaata ttactattga agagtacatt gaaatgtctg aagttgattt
    23641 taatgaaact gttaattatg aatttacatc tgacacttgt caattagcaa atagtattta
    23701 tcaatctctt tttaagtttt ttgataagaa aaatttctct ggcgatttaa tttttacttg
    23761 gaaatctcca tcattagtca aagaagggga ttatattggg agaagggatt cacaagtaga
    23821 taatcttaga gtaataggaa atatatttcc gaattatctt actaatcgaa aatatagcct
    23881 caatatgaat cgtaatggct gtatgggaga ttttcctcat gacttttttg atatatacct
    23941 agatcatgta gcaaaatatg cctacgaaca aaaagttaat aatattaaag agtattatcc
    24001 tttaaactgt aaaaagtggt ttagatagcc actttttgct ataatagagg cagtaaaaac
    24061 gaaggagttg gctatggaac actcgtcttg gcatgctttg ataaaggaac aattgcctaa
    24121 aggttatttc gggaaaatca atcagtttat ggaacaggtc tatgctcagg gaactattta
    24181 tccacccaag gaaaaggttt ttcaggctct cttgacaaca ccgcttgaag aagttaaggt
    24241 agtgattcta gggcaagacc cctatcacgg gccaggtcaa gcgcagggct tgagtttttc
    24301 tgtacctgac tctatcccag ctccgccatc cttgcaaaat atcttgaaag aattgtcaga
    24361 tgatatcggg gttaagaaat ctcatgattt gacagcttgg gctgaacaag gagtcttgct
    24421 tcttaacgct tgtttgacgg ttcctgctgt acaggccaat ggtcatgctg ggcagatatg
    24481 ggagcctttt acggatgctg tgattcaggt ggtcaatcaa ttagataaac cagtagtctt
    24541 tatactctgg ggagcttatg cacgcaagaa gaaggcctta gttaccaatc ctcaccatct
    24601 gattatcgaa tcagcccatc caagtccttt gtcggtttat agaggatttt ggggttccaa
    24661 acctttttcc aaggccaatg cattattaaa agagacagga caagagccaa tcgattggct
    24721 tagataagga gaaaatatgc ctcagttagc gacaatttgc tacattgata atgggaaaga
    24781 actgctcatg ctccaccgta ataagaagcc aaatgatgtc catgaaggga aatggattgg
    24841 tgtgggtggt aagctagagc gtggtgagac gcctcaggaa tgtgcagcgc gtgaaatcct
    24901 tgaggaaaca gggctcaaag ccaagccagt tctaaaaggt gtcatcactt ttcctgaatt
    24961 tacaccagat ttagactggt acacctatgt ttttaaagtg acggagttcg agggtgactt
    25021 aattgactgt aacgagggaa cgctagaatg ggttccctat gatgaagttt tgagcaagcc
    25081 aacttgggaa ggtgaccaca cctttgttga gtggctttta gaggacaaac ccttcttttc
    25141 agccaagttt gtttatgatg gggataaatt gttggatacc caagttgatt tctatgaata
    25201 aaggagaaag cagatgctac taattaaaaa tggtcgtgta atggatccca aatctggttt
    25261 ggatcaagtg tgtgatgtct tagttcaaga tgggaaaatt atcaaaattg cgcctgaaat
    25321 cactgaagaa ggagcagaaa cgattgatgc tagtggtctt gtggttgctc ctggtttggt
    25381 cgatattcat gtgcatttcc gtgaacctgg tcaaacacat aaagaagaca ttcatactgg
    25441 tgccctagca gccgctgcag gtggttttac aactgttgtc atgatggcta atactagccc
    25501 aaccatttca gatgtagaga ctttgcaaga agttctccag tcagctgcca aagataagat
    25561 taatgttaag acggttgcga ccattactaa aaattttaat gggcaagatt tgactgactt
    25621 taaggcactt ttagaagttg gagcagttgg attttcagat gatggcattc cacttgaaag
    25681 cagtaaagtt gtcaaggaag ccatggagga agccaaaaaa ctcaatacct ttattagcct
    25741 tcatgaggaa gatccaggat tgaacggtgt tcttggcttt aacgaaaata ttgctaaaga
    25801 acattttcat atctgcggtg ctactggggt ggctgagtat gctatgatgg cgcgtgatgt
    25861 catgattgcc tatgcaacca aggcccatgt tcatattcag catttgtcta aggaagaaag
    25921 tgttaaagta gtggagtttg ctcaaggttt gggtgcgcaa gtcacagcag aagtagcgcc
    25981 acagcatttt tctaagaccg aagcgctcct tttgacacaa ggaagtaatg ccaagatgaa
    26041 tccgccgctt cgtttggaat cagaccgtcg tgccgtgatt gaaggtctca agtcaggtgt
    26101 catcacagtt attgcgactg accatgcgcc tcatcatgta gatgaaaaaa atgttgagga
    26161 tattaccaaa gcgccatctg gtatgactgg cttagaaacc tctctgtctc tcggtttaac
    26221 ttatttggtg gaagctggtg agttaagctt gatggaatta cttgaaaaaa tgacatacaa
    26281 cccatccaag ctttacaatt ttgaagcagg ttacttggct gagaatggtc cagcggacat
    26341 cactattttt gatgctaagg ctgaccgcct tgtggactcc cattttgctt cgaaagcagc
    26401 taattcacca ttcatcggtg aaaccttaaa agggcaggtt aaatacacca tctgtaaggg
    26461 acaaatcgtc tatcaagctt gataggagtt ggaatatgaa ttattttcga aaacgtaggg
    26521 agagacaagc aaaatctaat agcggaattt actgtcccgc atctaatcgt tctaaaattc
    26581 aatatgaaac taaagaaaaa gctgaccatg cggttcaata tgataacgga ggtttagtta
    26641 gaagctatta ttgtcgtaca tgtgcgtgtt ggcatactac ttcaaaatct aataaacctc
    26701 cgctaagttt gaaaaactat ggtctgaaac tctttggttt agataaatca gaatagaaag
    26761 agaagtatgt ataagacaaa gtgtttacga gagaagttag tattattttt aaaaattttc
    26821 ttcccaatcc ttatctacca atttgccaat tattctgcct cttttgttga tactgcaatg
    26881 acaggtcaat acaacactat ggacttggct ggtgtatcta tggcaaccag tatctggaat
    26941 cctttcttta catttctaac agggattgtg tcagccttgg tgcctatcat tggtcaccat
    27001 cttggtcgag gcaaaaagga agaagttgcg tctgattttt accaatttat ttatttggcc
    27061 ttgggcctat ctgtggtctt gctggggatg gtacttttct tggcaccaac aatcttgaat
    27121 catattgggt tagaagcagc agtagcggca gtagcggttc gctatctttg gtttttatct
    27181 atcgggatta tccccttgtt gctctttagc gtcattcgtt ccttgctgga ttcgctgggc
    27241 ttgaccaaac tgtccatgta cctcatgctt ttgttactcc ctctcaatag cggatttaac
    27301 tatctcttga tttacggtgc ctttggtgtt ccagaactgg gaggggctgg tgctggttta
    27361 ggaacatcct tggcctactg ggtcttgctt gggatttctg ttctggtttt atttaaacag
    27421 gagaagctca aagccttaca ccttgagaaa cgaattccac ttaatatgga taaaattaag
    27481 gaaggcgttc gtttaggtct gcctattggg ggaactgtct tcgcggaagt ggctatcttt
    27541 tcagtagttg gcttgattat ggctaagttt tcgtccttga ttatagctag tcaccagtca
    27601 gctatgaact tttcaagtct tatgtacgcc tttcctatga gtatctcatc ggctatggct
    27661 attgtcgttt cctatgaagt gggagccaag cgatttgatg atgcgaaaac ctatattggt
    27721 ctaggaagat ggactgccct catttttgcg gccttcacct taaccttcct ttacattttt
    27781 aggggaaatg tggccagtct ttatggtaac gacccaaaat ttatcgattt gacagcgcgt
    27841 tttttaactt atagtctttt cttccagtta gcagatacct ttgcggcgcc gcttcaggga
    27901 attttgcggg ggtataagga tacagttatt cctttttacc ttggtttgct tggttattgg
    27961 ggcgtagcaa tccctgtggc tacgctattt gattccctaa cagattttgg agcttattct
    28021 tactggatcg gcttgattat tagtttgatt gtgagcgggg cgctctaccg ttggcgttta
    28081 actgtgatta tgaagagatt tgaatcttta gcaaaatcca aacgctaaaa agtttgtgaa
    28141 aaaatattct tgacaagaaa atcccttgtt tttacggggt tttctttttt attttgtgaa
    28201 atttctttta gaaaaacttt gacagtattt gccaaaagcg gtaaaatagt aaggtaagaa
    28261 gaaagttaga aaggcaagaa gatgtcaact ttagataaaa atcttttgct agaaatgttc
    28321 cgtaagatgg aagaaatccg ttgcatggac ttaaaaattg cacaattagt aaagaaaggg
    28381 aaagtgccag gaatgacgca cttttctgtt ggtgaagagg cagctaacgt gggggctatg
    28441 ttagctctca atccagatga tctgattacc tcaaaccacc gtggacacgg gcaagctatt
    28501 gctaaaggga ttgacctcaa cggaatgatg gctgaaatcc ttggtaaata cactggaacc
    28561 tgtaaaggga aaggtggatc tatgcatatc gctgaccttg atgctgggaa ccttggtgcc
    28621 aatggtatcg taggtggtgg tatggggatc gctgtcggtg cagccctcag tcagcaaatg
    28681 caaaataccg gtaaaatcgt tgtttgcttc tttggagatg gtgcgaccaa tgaaggtgtt
    28741 ttccacgaag cagtgaacat ggcttctatc tggaacctgc cagtcatttt ctattgcatt
    28801 aacaacggtt acggtatctc tgcggatatc aagaaaatga ccaatataga acatatccat
    28861 caacgtagcg ccgcttatgg aattcctgga atgttcatcg aagacggtaa caatgtcatc
    28921 gatgtctatg aaggatttca gaaagctgta gaccatgttc gcagtggcaa tggtccagtc
    28981 ttgattgaaa gtgtaactta tcgctggctc ggtcactcat catctgaccc tggtaaatat
    29041 cgtacgcgtg aagaagtgga attgtggaaa caaaaagatc caatcgaaaa cctccgcaat
    29101 taccttattg aaaataacat tgcaagtgcc gaagaattgg aagaaatcca agcgcaagta
    29161 aaggaagcag tagaagcttc tgttaaattt gcagaggaaa gcccattccc accgcttgaa
    29221 tcagtctttg aagatattta cgcagactaa ggagaaagag ataaaatgga aacaaaaaca
    29281 atgtccttcc gtgacaccat tatccttgct atgtctgagg aaatgcgtcg cgatgaaaat
    29341 gtgttcttga tgggagaaga cgtcggtgtc tttggaggag acttcggtac ttctgttgga
    29401 atgcttgaag aatttggtcc agaacgtgtc cgtgactgtc cgatttctga agctgccatc
    29461 tctggagcag cagcaggagc agccatgaca ggacttcgtc caatcgtcga tatgaccttc
    29521 atggacttct ctgttattgc catggacaat atcgtcaacc aagctgctaa aacacgttac
    29581 atgtttggtg gtaaaggtca ggttccaatg actgttcgtt gtgcagctgg taacggagtt
    29641 ggctctgccg cccagcgctc acaatctcag gacttaaggt tgtggcacct ggaacacctg
    29701 cggacatgaa aggcctgctt aagtcttcta tccgtgataa caacccagtt attatacttg
    29761 agtacaagtc agaatttaac caaaaagggg aagtgccagt tgatccagac tacacaattc
    29821 cacttggggt tggtgaaatc aaactccaag gaacggatgt aacagttgtt acttatggaa
    29881 aaatgcttcg ccgtgtggtt caagctgctg aagaattagc agaagaagga atttcagttg
    29941 aaattgttga cccacgtacc cttgttccgc ttgataagga tatcatcata aactcagtga
    30001 agaagactgg taaggttgtt ctggtcaacg atgcccacaa aacaagtggc tatatcggtg
    30061 aaatttcagc tattatttca gaatcagaag catttgacta tctagatgca ccaatccgcc
    30121 gttgtgcagg agaagatgtg ccgatgcctt atgcacaaaa cctagaaaat gcaatgattc
    30181 caacagttga aagtatcaaa gatgcaatcc gaaaaactta taacaaagaa tagagttaca
    30241 taatataagt tatgtaacta aaacaaagct gacgagaaac tttatatctt ttaggtgcag
    30301 agctcttcgt cattaatatc ttagattaga gcacgggcta aaagctcgga aaaaagataa
    30361 atctccttgg cttcatcgaa gccaaggaga tttcctattt ttcagtcgct tttgacgccc
    30421 tttgtatcat aaatagaatt ggagagatca tggctgatga caagctaaga gcgactcctg
    30481 cagctagaaa gttagcggat gatttaggga taaacctcta cgacgtttct ggctcaggtg
    30541 caaacggtcg tgtccacaaa gaagacgtgg aaacttataa agacacaaac gtggttcgca
    30601 tttcgccact tgcaaaacga attgccctcg aacataacat tgcttggcag gaaatccaag
    30661 gaaccggtca tcgtggtaaa atcatgaaga aggatgtttt ggccctgctt cctgaaaata
    30721 tcgaaaacga tagcatcaaa tctcctgctc agattgaaaa agtggaagaa gtccctgata
    30781 acgtaacacc atatagtgaa attgagcgta ttccaatgac accaatgcgt aaggttattg
    30841 cccaacgcat ggttgaatct tacttgactg cgccaacctt caccctcaac tatgaagttg
    30901 atatgactga aatgttggct cttcgtaaga aggttcttga gccaatcatg gaagcaactg
    30961 ggaagaagac tactgtaaca gaccttcttt cgcttgcagt tgttaagact cttatgaaac
    31021 acccatacat caacgcttca ttgacagaag atggcaagac tattatcact cacaactatg
    31081 tcaatcttgc catggcagtt gggatggata atggattgat gacacctgtt gtttacaatg
    31141 ctgagaagat gagtctttca gaactggttg tagcctttaa ggatgttatt ggccgtacct
    31201 tggatggtaa attggctcca agtgagttac aaaattcaac attcacaatc agtaatttgg
    31261 gaatgtttgg tgttcagtcc tttggtccga ttattaacca acccaactca gctatccttg
    31321 gtgtcagttc gacaatcgag aagccagttg tcgtcaatgg tgaaattgtg attcgcccaa
    31381 tcatgagttt aggattaacc attgaccacc gtgtcgtaga tggtatggct ggtgctaagt
    31441 ttatgaagga cttgaaagag ttgattgaaa cgccaatctc aatgttaatt taagagcaag
    31501 agtattcatt tttaagatat agataaagga agcaagacat ggccttagaa gtaattatgc
    31561 caaaagtcgg cgtggatatg acagaaggac aaatcgtcca atggaataaa aaagtcggag
    31621 aatttgtaaa agaaggagaa atccttttgg aaatcatgac tgataaagtc agcatggaat
    31681 tggaagccga agaagatggg tacttgattg ccattctcaa aggagatggt gaaactgtcc
    31741 ctgtaacgga agttatcggt taccttggtg aagaaaggga aaacatccca acagctggag
    31801 cagcatcgcc agaagctagc cctgtacctg tagcaagtac ctcaaacgat gatggtaaga
    31861 gcgatgatgc ttttgatatc gttgtgattg gtggaggtcc tgctggttat gttgcagcca
    31921 ttaaagctgc ccaattcggc ggtaaggttg cccttgttga gaaatctgaa cttggtggaa
    31981 cctgcttaaa ccgtggatgt attccaacca agacctacct tcataacgct gaaattattg
    32041 aaaatatcgg tcatgctgca aatcgtggta tcgtgattga aaatcctaac ttcactgttg
    32101 atatggaaaa acttttagaa actaaatcta aagttgttaa tactcttgtt ggtggtgttg
    32161 caggacttct tcgtagctac ggagttactg ttcataaagg aattggtaca atcactaaag
    32221 acaagaacgt cttggtaaat ggttctgaat tgcttgaaac caagaaaatc attcttgctg
    32281 gtggttcaaa agtcagcaag atcaacgtcc ctggtatgga atctccactt gtcatgacta
    32341 gtgatgacat tcttgaaatg aacgaagtgc cagaaagcct tgttatcatc ggtggtggag
    32401 ttgtcggtat cgaactcggt caggccttca tgacatttgg ttcaaaagtg actgttatcg
    32461 aaatgatgga ccgtatagtt ccagttatgg atgcggaagt ttctaagaac cttcgcttga
    32521 tccttgagcg taaaggaatg accatcttga ctggtactaa actgcaagaa atcattgagg
    32581 aaaatggtca acttcgtatc aaggttgaag gaaaagacga tatcatcgca accaaagctc
    32641 ttctttcaat tggtcgtatg ccagaccttg aaggtattgg agaggttgag tttgaattgg
    32701 atcgtggttg tatcaaggtc aacgaataca tggaaacttc agttccaggc atttatgcac
    32761 caggtgacat caacggtact aagatgttgg ctcacgcagc tttccgcatg ggtgaagttt
    32821 ccgctgaaaa tgcccttaaa ggaaatcatg cagttgccaa attgaatttg actcctgcag
    32881 ccatctacac tctccctgaa gtagcagcag taggtttgac agaagaacaa gcccgtgaga
    32941 aatacgatgt tgccatcggt aagtttaact ttgctgctaa cggtcgtgct attgcatctg
    33001 acgctgctca aggtttcgta aaagttatcg ctgataagaa atacggagaa atccttggtg
    33061 tacacattat tggtcctgca gccgcagaat taataaacga agcatcaagc atcatcgaaa
    33121 tggaaatcac tgttgaggaa atgctgaaga ccatccacgg gcacccaact tactctgaag
    33181 tgatgtacga agcgtttgca gatgttctag gaatggccat ccattcacct aagaaaaaat
    33241 aaaacgaaaa tagattagac tggaaggtta tttccagttt ctatcatata tcatataaag
    33301 taaagggata tcatgaaata cattttttca gaagaagaat tggccgaaat caatcgcatc
    33361 aaggatacta agtttggaac ttgggactgg aactatggta aatcacctga atttaacgtc
    33421 cgtcgtggaa ccaaattcac tagtggtaag gttgaagtct ttgctaacgt tactgaatca
    33481 aaaatccaag acatcaagat ttatggtgac ttctttggta ttgaagacgt tgctgcagta
    33541 gaagatgtcc ttcgtggggt gaaatacgaa cgcgaagatg ttcttaaggc gctaaaaacc
    33601 attgatatca cacgctactt cgctggtatt agccgtgaag aaatcgctga agcggtagtt
    33661 ggataaatcg agtaggggat aatctctagc ccctctcaca ccaccgtacg tgccgttcgg
    33721 catacggcgg ttcaactaac ttttaacgca tgtcgttcaa ggtaataatc caaacacgaa
    33781 accagtccac gtttttccag gactggtttt gatatagcac gtttaagtac ctacttctga
    33841 gctactaatt gataatggtc gtcccagcca gataccttat ctgctatcca tttaggaact
    33901 cctaacttaa gcaatcccca taatcgtctc gatttcttct tccattgctt ccagataatc
    33961 actcgtaggc gagtacgcaa gcgctcatct atgctagtga ctatactttt catattcccc
    34021 aatgagaaat agtttatcca gcctcgaatg gacaaattca gttgctcaat acgtcttgtt
    34081 aagtctatac tccatttcat ctgtgttagt ttcttcaatt taagcttaaa tctccgaaca
    34141 ctatcttgat gtggacgact tttccaacca tctgatgatt tccagaaccc gaaacctaga
    34201 tatttcaact ctcttggtct ggtaatctta gtcttggtta tgtttacttt caaacctagc
    34261 cgtttctcaa taaaataact gactgaatac atcacacgct tagcggcagc ctcgcttccg
    34321 actgtaatca cacaatcatc tgcgtagcgc acaaatcgaa gtcccctctt ttctaattcc
    34381 ttgtccaatt cattaagcat gatattggat aagagaggag ataaatttcc tccctgtggc
    34441 gtgccaacta gcgttttatg acgctgacca ttaatgataa cacctgaatg aagatactta
    34501 cgaatcaagg attccgtatc tccgtcttcg ataatgttat gtactaagga catcaatcta
    34561 tcttgaggaa ccgtatcgaa aaatttctct aggtctatat ccactatcca ctcatagccg
    34621 tcatttaagt actctaagaa cttcatgatg gctttttcac atgacctatt tggtctgaaa
    34681 ccataactcg tatctgagaa atggggttca caaatggggc tcatgacttg gacaatggcc
    34741 tgttgaatca ttctatccat aactgttgga attcctagtt gacggatgcc tccgtttggt
    34801 ttaggaatct caactctaag aactggttga ggcttatatt ttctctgttt tatcagttcc
    34861 ttagtcaagc gccagttttg tctgagataa ttatccatct cttcgatagt cattccatca
    34921 atcccagctg agcctttatt ggattttact tgattgtagg cttcaagcat attttcgcgt
    34981 gataatatct tatctagcaa ttttgacatg tgcgtattcc tttcttgttt tggtgcctga
    35041 gggatatctt atattggtga accttcatct agtcaatacg tgacagaggc cagttctata
    35101 agaccgcttg ttttacagac acaattgaag taggattact tcaattagtt gttcacccct
    35161 tcgctccact tccattacag aagtttcctc actactatgg gttcggctga cttctcatga
    35221 ttcgttgtta ctacgctttc atcgctcatg agacctcacg ggataagtcg tacatctttc
    35281 ctcgtttata caagatatga ggacgttaaa aggttacagt gaaaatagga aatctgacgc
    35341 agagtcttta gactctagaa agatttatct ttttcacaca aaccttagtc cgaattcaat
    35401 tactctcgtg atttacgcat ataggttacg actacctttt tggactttag agtttgaggc
    35461 cccttatccg ctatatacgc cttactatca cgttcctgtt cgtagagcca cgatttcgct
    35521 atcccttcct ctccctgcta cctcacgata gtcaggcttg ggaatcgcta ttgggttcac
    35581 cggtagcggg tgcccacgga ggacttacac ctcagatgca cgacatgccc gtcgtacttc
    35641 aaaaagaagt tggccaacta accaacttct ttttttgata tttatttaca taatttaaaa
    35701 tacgtaaaat tataaactat ccagagcatt cttttgttca tcactaacaa tatgggtata
    35761 gaggtcagtg acttgtgtgc tagcatgccc tagttggtga ctgactaaaa cttgtgattt
    35821 agtcgcatca tagagcctag ttgctagcgt atggcgcagt ttatgggggg ttacacgtac
    35881 tttaaaatcc tctgagtatt tagcaaccat tttctcaacg ctagaagcat cgatacgatt
    35941 aggaacacct ctgtagagag ttaaaaaaag ggctgtatct gttttttccg ttttatagcg
    36001 ttgattccga atggccagat aattctctaa ataaggttta gcaaaagcag cgacattgac
    36061 taagtcacgt ttgccacctt ttcgagtaac atcaataacc atcattttta gattgagatc
    36121 tcttagatct agattaacag cttcagataa gcgaacacca gatgccaaga gaagggcaat
    36181 aatggctaaa tctcgttctt tatttttgtt gaatgatgag agagctcgat ttgaaagctg
    36241 ttgtgggtgc tcttgatcga tataagttag aaaaccttct gtttcatcac ctagaaagag
    36301 tttttgcttg atattttcag ctctggcagc aagggtttct ttctttttct tggttgaaac
    36361 ttttttcatt acattacgat agaaataagg ttccccctga tcgttttcaa cctcctcggt
    36421 tagatacttg taaagactag aaagtgctga taaggttcga ttgatagttg tctgtgaaac
    36481 accttgtttt gttgtattag cattcagcaa gggacgttca cgtagataaa ggataaagga
    36541 ttccatgtct ttcttagaca tattttccaa aactgataaa ggaatatcgg atattttatc
    36601 agcgtttgaa ataccagact ccaaaaccca gctgaaaaat cggtcatatt ccttaaggta
    36661 ttcgtacagg gttgtaaaac tgtagggcac agccagctta gattggtagt attccagaac
    36721 ataccagggc atgagttgtt ttagtttgtc gattcgttcc agtaaaatct cacgtttcat
    36781 gtattttctc cataagtaag tatactagta gtatagcata gacttgtata tttttcaaga
    36841 aaattatagt ttttcagaaa gatgttatag gagtttttca aagtgataaa aagacttaga
    36901 cctacaaaca aaacagaata aggaaaataa taaaaatctc acccactaaa cttctgttaa
    36961 tactacataa ctgaagagct atataaggag ctatgagata caaaacacat tgtataatag
    37021 attgaaacta gaatagtaca tctggacttc taaaacattg ctagaaattg atttgattgt
    37081 cctgattgtt ttatcatatt tctatttcat ttcactatat aattgctatt gttttctttt
    37141 tcatgatttt aatcttactg tacagatttg atacagtaaa ctcctttcta gctttatact
    37201 ttatcatttc taacttaatt atagtcttat ttttaataaa gttcaattat ttatatgtaa
    37261 aattcctcat cagtaaaaaa taaccgatct catttctgag aatcggtttt ctaaataaat
    37321 caagctgatt atttacatag cataaattat gtaaataatc atactacaac aacaaatctt
    37381 tgacttttcc aatttcactt tttggaataa ccaggtgaat catatcaccc agatacattc
    37441 tggttgagcc gttaactgtt tggctcttgc cattatggac ttgagttgtg atgaggacgt
    37501 tgtgtggtaa gttgagttca tgaacttgtt tcccagcaat tttatcagaa actggtattt
    37561 cgataagtgt aacttctcct tcgctagata cttcttctgg aagcattttt tccagcatgg
    37621 cttcatagac tggcgtacct ttgagcaaat ccatgataat ataagaaaca agagtgacaa
    37681 gaccaagtgg catgaggttg cgaatatctc ctaccatctc agttacgagg atcatagcgg
    37741 ttaagggagc ttttgatatg gctccaaaat agccactcat tcctagaatg acaaatatag
    37801 ggaattgctc ttgactgaca agtccaagat tgacacagat aacaccaact aaggcaccaa
    37861 gcaaagaacc aagagctaaa atggggagga aaattcctcc tggcagtcca cttccatagc
    37921 taatcatact ccaaataaag cggatcaaaa agtaagctaa taaaacttgg aaactaaaat
    37981 tttgttcagt taaagaaagg acaagctgat ttccgccacc aaggatttga ggtaagaaga
    38041 ttccgactgg tatgataagg ataaaagcca agatgggata ataagctcta tccaaatgga
    38101 ttttttgacc aatcaagtca taaactcttc caacgtttaa tacagctttc tcatagagaa
    38161 agcctgaaaa tccaaggaaa attcccatga cgagatatat ccaatactga tctagggtca
    38221 tgggaggaat gttatctggc atatccaata ctggtgtcaa accgaacatg agtagagaca
    38281 caaagtttgc tacgatgctg gctgctagag ttgagaccca gaaaaagcgc gaaaaatggt
    38341 gatagacttc ttctacaaca aagagaagtg ctgcaatagg agcattaaag gctgcggcta
    38401 aacctgctgc agctccactg gcaatcaagg agcgttcctc tactggactg gatttgagcc
    38461 acttggcaat tcctttacca ccaactgctc caagttgaat actgggtccc tctcgaccca
    38521 gcatgagtcc actggcaata gcaagaatac ctagcacata ttttttccaa agaatgcccc
    38581 accagttgag ggacatgagg cctttcagtt cggcttcgac ttgaggaatt cctgagcctt
    38641 taatatcttt ttctgaccgt gttagtttgg cactgagcca acagatgagt atataaaaca
    38701 aaaccagtac aaaaagattg cgcactaagt acccttgatc ttgataaact ccttgtatca
    38761 ggtggaagcc cttttcaatt aagaaacgaa aggatccgac gataattcca acgatgaggc
    38821 cgacaatgat tcctcgacca acttgggata gtatagtgct ggatgcaaag gcgaattctt
    38881 tcttagaacg gactatttcc gactgttcct ccatggtatt tcctttcaat taactttctt
    38941 ttttacctaa aaccagtgat ttaacgggtt caaagctggt tcggtgaatt ggggtaactc
    39001 ctagttttgt gaggccttcc agatgtttag ctgtgccata tcctgcatta gtagcgaaat
    39061 catagccagg gaactgctga tcgtattcct tcatcaattc atcacgtgtt accttggcta
    39121 ctatagatgc tgctgcgata gagagggagt tggcatctcc tttgataatg gaggtttgtg
    39181 aaatgggcaa gtccagtttc atggcatcaa tcaaaaggtg ctctggttga gggctgagct
    39241 gggagattgc ttcttgcatg gctagtttgg ttgcttcata gatgttgact tggtcgatga
    39301 cctgattatc tatgatacca attccaatcg acaaggcttg gtcttgaacg gcttggaaaa
    39361 tctccagatg tttcttttta ggaattttct tgctgtcgtt gagaccttta atcttacaat
    39421 ttttaggtaa aataacggcc gcagcgacta caggaccagc aagaggacca cgaccaacct
    39481 catcaatacc tgcaattaag gtcaatcctt gcttataaag ttctttttca taagaaagca
    39541 tggattccaa gcgcaaattt tcatctaatt cagcttgaat ggctctttta cgcttgctga
    39601 tttccttttg aactcctgag cgattatcct tttcaagctc taaaaaaata gggctttcta
    39661 actccttgac tgtcacaagg agttctttga tttctttaat cgttgccatc gaggtcttcc
    39721 aatgtatcta aggtatagtt accgagtttg ccatcacgga cttccttcac gaagagactg
    39781 taaaaacggt catagtcatc acggaaaccg agggcgcagg tcatatccat aataatcaca
    39841 ggcgcttctt cttcaatttt catttgtttg aagcgttcag ccagcttttc tggataatgt
    39901 tctttgaaat aattgatacc aaaaatggta acctcatcca taggaagcaa ctgatccttg
    39961 atagctccag tcaatgccaa cttaagtgca acagtttcat cctcaaactt aggccagaga
    40021 atccccggtg tatccaagat ttccagatct ttattggttt taagccattg ttgacctttt
    40081 gtgacccctg gcttgtttcc aacaacagca atctttttac cagccaaacg gttcatcaga
    40141 gttgatttac cagcgtttgg aatcccaata atcatggtac gcaaggtttc aatctgaatc
    40201 ccacgttctt tctggcgagc aatcttatca gccatgagct tcttggccgc atctgttaca
    40261 acttttacag tcacttgctc tttggagttg atagctagcg tctggattcc ttgtgattca
    40321 aaatactgac gccattcctt ggtcattgct ggatcagcca agtcggcctt gtttaaaatc
    40381 aagagttttg gtttatcacc aacaatcttg gtcaacatag gattttgact agatagaggc
    40441 aagcgtgcat ctactaaaat cgtcacaaaa tcaacaaatt ttaaattttc ctgcacctgt
    40501 cgacgcgctt tagacatgtg accaggaaac cattgaatag tagccattga gttttttcct
    40561 ttcgtagcaa ggatttagat cccctatttt attttactat tgtttgaaca tagagagttt
    40621 tcaaatgaat gatgtccaaa cagttcttgt tttatgacat agaaatctac tttatattat
    40681 atcatgcctt ctttattttg tccgatgata gccttttacc ctatctttta ccctatatag
    40741 aaaaaagcca tcaaatgatg acttttcaga gggagcaaaa aactgttccc tttatatttt
    40801 aaagatttaa atgtcttttt tgaacaatgg attaaagaaa ccgtctgtgt ttttaagaag
    40861 ggctttaaag atcttggatt tcaagtccac tgtatttttg aaatgatttt taatttttgg
    40921 atctgacata ccatcaagat ctttttgaac tgcttcagca aataaagtgc gcaactcatc
    40981 atagttgcta atatggactc catcaatatc gatagcctca aaacctttct tagctttagc
    41041 aagaacttct tcgtaccaat gtctcttcca ctcttcaagg gtactaaagt ttccttttga
    41101 tactttagta attattagct tatcgcttag taaaccatgg ttgtttttat ccgcttctgc
    41161 tttgtattta tttgacacat aactgataaa tccattttca taaccatagt aaccccacat
    41221 acggaaagca ttgtgcttaa acgataatga accaggtgca ccatcactcg tatttccacc
    41281 gtaaattcct gccatcatat tgacatttac gtaagctgat tttggtgtaa aatcctctgg
    41341 tctataacgt ccgttacctg gattaccatg aatggtcatg aaattattat ttactaagtc
    41401 atcaatggaa ttcagtggtg ttgttctctc agcgtctgtc aagtcacgca ctttgtccca
    41461 ttggtgagga gcacttagtt tatttctatc cattggtcga cgtatttcac ggtcaatttt
    41521 cttgaaccat ttgctattgt caccatttaa ttttggaatt acagcatctg cttcaacata
    41581 atccaacatc attaacgctt cattgtagtt cttcatgtag cgatcgatgt cttcacgagt
    41641 ttgtaactta tcaggattat aattgtacca ttggttacca tcattttcac ggtgataagc
    41701 catgttaagg cctaaagcac catattctcc gtttggattt gataccgatg gcgtttgcaa
    41761 cataccttga gcaaaggctt ctaaatccgt accttggcga tgccaatgac caccatagta
    41821 aaccatacga tcattaacgt gagtagtttc atgtgtaaat gcggatgttc caaaatcact
    41881 aattaaatct gtcataacga aataaactga atccatcggt tgcggtgctg caaaaatata
    41941 tgcatatgct ccgtatccat attggtaagg atgatacttc ccaatacgac caaagaattc
    42001 cctgactgga ttatagtctg gttttccatt tctatgtccg aatctatcag gccagccacc
    42061 tggagcgtta tgattatccc atacaggagt tggaactaca ttttgactct taagaagttt
    42121 atcgcggaca ttatcagtag caagacgtga ccaaaaatct aagtaattaa cttgctcttt
    42181 ggcacgtaga ttaatctctt ttttaaaggc ttcacgttct tcttcagtat ttttgttgta
    42241 tttttcaaac gaactaaatg agatagtatt atacgttgaa atcataaata aatgtgcatt
    42301 tttcaagtta agaagaggta aaatcatacg cccatgctgt ccattattaa ttccttcgta
    42361 tagacgatat tttttgttag caaatgcagg gttcgttgat ggttgttcaa ctacatacgc
    42421 attcttttca atagctttct taaaccagtc atttatatct gtatggttag tcaatagctt
    42481 catattgtaa tgtaagaatc catttaattc atttattccg attgttccac ctatagtttc
    42541 acgataagct tctaaagttc tatcaccttt aacatttctt tcacttgaac caattttgat
    42601 taagaaatct aagatattaa cattcttacc ataaaaatca ggtttaaaca tcataatatc
    42661 tttaattgat aacttatcgt atttaaaacc ataatattga tttaagtagg caagtcccat
    42721 catgatttta gctttgttgt cttcaacttt cttcagtaaa gcacgctcga ctgcttcccc
    42781 ccatttaact gatgatcttc attttctaaa atctgactaa caagtttttc taagtttcct
    42841 tttagttctg cgaaactttc ttctaagtac aagcctttaa tatactccgt cttcttctca
    42901 ggagtatatt aaaggcttct cacgtttatc catcaaagca cgaacttcat ctgaaagtaa
    42961 ggtaacacta gctaacttct ctttaatacc gcttgctaac tggttacgat tcttcataac
    43021 catatttgga gtatagacaa tgttttgacc tgctacatca tactctttta cttgatctac
    43081 tttagagtca gttttagcag ttacagttaa ctcttccttt gtaccatcag catagtgaac
    43141 cataatctta tcaatatctg acaaatcagt tacaaactgc cctgctttca tacctgttac
    43201 agacagaacg gttttcttaa caagattgga ctcatctgtt aacttattcc cttggtttac
    43261 gatccactct ttattataga acggttgaag tttttcaata ttgcgatagg cttgttcacg
    43321 ttcagctttg taatcttgcg ttgtcttata ctcattatca cgagttgtca ggttgttgag
    43381 tgtgtttaca agtggatccg tgatttcata cttatcagca gtgatattga aggtggcaat
    43441 acgtttatca gcttcagctt ggtctacacc ctgaatttgt tttgaacgtt tatatgaaac
    43501 attgcctgac gcaacatctc tcacatatac attgttcttg aagtaatgga atccaaagtc
    43561 tgggtcgccc gaatccactg aaccagaacc gtacatgatt tcaccattgt ttactttcat
    43621 catgctgacg ttgttttcaa cccatcccca attgtagtta tcgtgaataa caccaccact
    43681 ttgaccatga tttttaagtg tcatagtacc tttaacaaca gatttcgtta agcgacctcg
    43741 ttgttttaca tccatagggt ttacaccatg gtcaatttta gcaattagcc caccgacctt
    43801 agagttgttg gctttgatat cagcatcaat atatgagcta tcgacattac ttctccaact
    43861 ttcactaaca agtccaccag accaccagcc tttatctcca agactgttaa tcttaccaat
    43921 aaatgctaca ttgcgcatat tagcttcatc taacttatta acagcaccgg ttacatcgtt
    43981 atttcctgtt actgaaccta ctactttgat attttcaagt gtagagttct taaacatatt
    44041 accgataggg gcaactttat cagcccaagg catgttgata tttacattac ccaagttaaa
    44101 gtttttgagt gtagcacctt cagcttcatt aaacaaaggt ctttctaagt tatgaatcgt
    44161 gtattgatga ttctctacac ttgataaagt acctctaaac ttaaccataa cataagcttt
    44221 acctgctggc ttaacgttaa ctgcattcaa atctgcacca agtttaaact caccggtagg
    44281 atttgcttgc atatcttttg ctaaatcatg gaagttgtaa taaaccttat cctcggtagc
    44341 cctcggtttt tcaaaataat aagtgtaagt gtctcttaac ttaccgtctt tgtcacgttg
    44401 aactaagtca ggtgcttttg ctgttacctt gtaaagttgc ttaccttcct caatgacctc
    44461 ttcaatctta tcaattgcta aacgggtcac tttgttttct ctggaggtta cttttaagta
    44521 atagttggta acatcacttg gaagagaggt taagtgatta ctatcacttt cgacaccgct
    44581 ttcgttcact tgtacgagac ttgtgtttgc aatatctttc aactcaactt tctttaaatc
    44641 taaacgtaaa ggtctatctt ccaaagtcga tacttctgca cccttaccta catcataagt
    44701 catagtagtt gaaatcgtat aatctttgta ataatccaag ttctctaaga cttgagataa
    44761 gttatcggtt tttaaatcaa ccgttggttt ttcttttgta ccttttacaa gaatttcagg
    44821 cttcatttct ttcaaaattg ttactgtttc aactggttca ctaatttttt tgccatgtaa
    44881 ctcttcatag ctagtaacaa tttgacgttc gccatcctca ccaatttgtt taacagaatt
    44941 atcgcctata aatttggtag gatcagattc ttctatagtg gttttaggaa tagtctctgt
    45001 ccgaatatcg gtatgtaaag aaggtgactc ttctctttct gatgcaactt ctgaaactgt
    45061 agatatcggc tcagtatact ctggaatgtt gctaacgggt ggctcaatca agtttccatt
    45121 ttcatctact cctgctgtac ctactggctc agtatattct ggtttctcag ttttaggtgc
    45181 ttcgtcagga accataccta caggttgagt gtactctggt ttttcgctaa caggtggttc
    45241 aatcaagttt ccattttcat ccacttctgt tgtacctact ggctcagtgt atgctagttt
    45301 ctcatgaact tcaggctcaa caaggtttgc acctattggt tgcgtatagt caggcttctc
    45361 atgaatttct ggttcccctt tttcagtcac aacttttggt tgctcaactg gcgaaacagt
    45421 tgatgctgga gaaactgacg aaacagttct atcatcaagc tccaagtaac caacatatct
    45481 gtaactggaa atttgcaaca caccatcacg tccagactca tggatgttag cattcaaatt
    45541 aagtgctgaa gcagttgata gtgtaactaa acctgtcgcc cctacaatca aaaatgtagc
    45601 tatttttttc ctctttttat cttttgtgat aatcacaata agactcccga tagctaacaa
    45661 acccaatgca gtcataatag attgagaact tcctgtgttt ggtaatgcgt ctttttcata
    45721 aaccaaagca tatgactctt ttgatttatc aggtctacct gatttcagtt gagcacgctc
    45781 attttgtgtt aaattactat aatctaagta atgataaggc gatgcaccaa caactgacgg
    45841 tgcgaataaa agactcccca agaataccga accaacaata ccctttattt tccgaatgga
    45901 aaatttatct tttttaataa tgacaattct aattctctac attcactttt tatttcctaa
    45961 tagtaaacac tattttttat tctcaaaaat tgaacttcta aaatcatcgg tttggtcaag
    46021 ataagcttta aagattgctt tcttgagctt gtggacttca ctatctatgt ctggattgta
    46081 gttattccaa tggtagtaat tgtgttctgc atccttacga acagcaacgt ccattaattt
    46141 ctgtaattca tctacactgc ttgtagtttt cttggcaaat gtttgccaag gctgtgttgt
    46201 atcattaaaa gtaactttat tcagtctatc aaattgagct acacgttcat tatacatagc
    46261 tttcttgaat tctgtccaag tttcatattg accgttaaat actttttgaa gaacaagttc
    46321 atctgtcacc aatccgcgtt ctttaccata aatagttatc tttttaccat tttgtttggc
    46381 aacttcttcg tattggttgg aaatatatgg taccatacca tctttaaagc ctttagcagc
    46441 tagtagttca taggctatac gacgtcccat caggtcacct ggtgttccta tatcactact
    46501 taatgctgca taaattggtg caaataactt aatagtgaag tagccatttc tttcgtattc
    46561 tttagacttg tattcacgag ctgaaaggat gttattatca atcaaattct caaagcttgt
    46621 cagttttttg gcatcttctt ctgtcagatt ttgtactacg ttagtagcgt aaacctcatt
    46681 tccatcttca cgatctttca cgtatttatt ctcgattttt ctcagggccg tcattttttc
    46741 tgttgcagat agttgactga ttattgattt tccttcaaga tattctaaca tataaataac
    46801 atcaaacata ttgtggacat attgcttcaa atcatctgca ttattaaatc tcgtggttgg
    46861 atcaagtact tgtaatcgtt gtccttctgt actatccgat tttgaatgtt ttaagatcga
    46921 gttgatggtg atggttgcgt catttggatg gtctggcgct tgtagtaatc ctttagcaaa
    46981 gaactctggt cccagtccac ttcttctgcc atatccgcct agataaatgt cctggtctga
    47041 atcgtgcgtc atttcatgag tataggtaat ggcaccatcc ttatccaaca tacgataacc
    47101 catataataa acagcatccc ctgtagcgta agcaccgtgt tcattatgac caaccttatt
    47161 tccaacaggt ccaaagaaat gttgcattgc aggatttgga tcatcaaaag ttgctacttt
    47221 tttagccttt ccttcggtat gatcatcacc aaatttataa gcatcataaa gcaagatatt
    47281 tcgataaagc ttttcacgct ctttttcatc tagaatacga taccaataat catagtgatc
    47341 tcgctgacgt ttggctgtct cacgcgcgtt ttcttcaaca aagctattta gatcaccact
    47401 tgcttgatgt tctttattac gatatcgatc ataagcacca aaacctagac tagatatggt
    47461 tgaaatgaca aatactgatt tttctggcaa ggtaagtaga ggtagtacca tgttacggta
    47521 tttccagctg tcgctagtga ttcgatcata gacaccgata gagtacttgc taccagcttt
    47581 ttcctgatta gcttttactt ctagaatatt agatttttct tcaacgatat aagccttggt
    47641 ctgtgattta aaccagtcat tgttagtttg agtaggtgca aatgctttac gatagccttc
    47701 taaagcacta aacagatctt ttgtaccgta gttattcgtc agcaaggcat tgtaagtaac
    47761 cacattattt tttgccaaga gattgttgta gccagattta cctagttcaa taatcgtatc
    47821 aagaggagag gtatttccct taccaaagaa atccatatgg aacataagca aatcttttgc
    47881 gctagcctta tcaaatttga aatcatacca gcgttctaga taggttaatc ctagcatcaa
    47941 ggcttctttg tttcgcttga ttttatcaac aatgtaattg tcaattatat cattatttcc
    48001 agaaacagct gcatcagctg aaagtaattt tttaagagtc tcagtcaagt gctctttggt
    48061 cttagcgaat tgctcatcta gatagagttc tgttaattta acattatcag agattcctaa
    48121 caaattctta agagaagttg gatcatactg aactgtattt aaatcatttt taactctgtc
    48181 tattatagat gtataatctt ttaggaaagc atttggtgtg tatactagac ctgtagttcc
    48241 aatagtatac tcagccagat ttgcaaagtc actatggtag gttacgttta ctttctcaga
    48301 tgttccgtct ttgtaatgta gtagtaagtg attgatagag ttcttatttg aagtgatatc
    48361 agagactact tcctcatttt tcatagctac aacagacaac aattcttttt taaacaggtt
    48421 atgatcagta gataattgat ttccatattt cacaatggta tctctattat agaaaggcaa
    48481 taatttttct atatttttat atgcaatatc tcttgccact tgataatgag ttgcctttgt
    48541 ataatctaca tcctgtttaa cagaatttgt gaaatcttct acggttatag tgtgtttttt
    48601 agtaatctgc tctttcttag cttgaactgc tgttttttca atctcagtac cacgttctac
    48661 agtggaatca attgacatta cctcatctcc aactgcttga acattgacta ctttattgtc
    48721 tttattactg taaactgctt ttttcttcat accattgaag tggtaaccag aaatcgcatt
    48781 cccatttgta atattcatat cgcttaggac attttgtaga atcccagaat tgtcctccgt
    48841 gctagagcca tttgtccaaa gggaacctgc aactccacca actctagcaa atggtttaac
    48901 attatttatt tcaccttcag catagctatt ttgtacagtc gcattatttt ctacgatacc
    48961 tgcaattcca ccaatggttt gatttgagta ttctgcatta cttgaaatgg ttactgttgc
    49021 aatagaacga tctacactag cattcgtacc agttaattga ccgactagac caccaattgc
    49081 atactgagag gttgtaacga aggtatttgt tattcttcca gtgaagctac tattacttat
    49141 ggtagaatta tcaacttttt ggacaagtcc tccgatacct agctcaccag caatgattcc
    49201 atttgcgtga acgttatcta aagttgaaga atttgtggct tccttagcaa ctgatgcgac
    49261 atgattctta ccagaaatat tgacatcttt caaggtgaga ttctgaatag tagcattatt
    49321 taatgtatta aataacggct ttttcaaatt atagatagca taatgtttac cttgatgact
    49381 accaattaat gttccggtaa atttacttgt aacataactt tcttggtttt catttaactc
    49441 aaactcgcga gcattcattg ttgcaccaag tgtgaatgtt ccacttggtc tactattcat
    49501 atcagttatt aattttttaa atgatgtgta gatagggcta tcgttttgaa caagttttgg
    49561 aagataataa gtaaaattgt cttggtattg attgtctaca gattgcttca agtgttccaa
    49621 tctagctgta attttataga ctgctttacc gtcttttgta gtgtcttcaa tgtttgaaac
    49681 tgggagcagt acatctttaa atttagctga cttcactttg atgaaataag cagatttatt
    49741 atctggtact ttatctaagc ttgtatgttg ttttgattga ttgccttcat aactatagag
    49801 ttccacatca gaaacacttc ttagttctat tgttttctct tgttcttcta cttttttatc
    49861 aggttctact tcagttttat gtttaatttc ttcgctttca tttgaattgg atgtttttga
    49921 ttcagttgat acatcctctg gcgaatttcc ttttggttgg tctggttctg tttgtccgct
    49981 ctctgttatt ggatgagcag aattttcagg ttttgttgaa gtttcgtctt ttgactcatc
    50041 tttttcaggt ttatttgttt cttcaactgg tggttttgaa tcactaggat tactggacac
    50101 ttccccagta ttttcgttag atgtatctgg tgatattttc tctgaattcg ttgttgattc
    50161 ttctgcaggt tgaactggat tttttgctcc ttgatttgag gttccttctg tagtgccttc
    50221 tgttggattt actggaactt cttcagtttt ttctggttct tgttctttcg gcttctcgac
    50281 tggagttgca tcttctcctt gttttccaag attctctccg ttttgagaag aatctacggt
    50341 tggaggtata gagtgacttt ccacttctga gttcatatca ctagataatg tatcagcttt
    50401 agttgcagcg gactctgtag ctacagctcc aacttgtcca tccctaaatt ctggaacagt
    50461 ttcatactgt ccgttaatca cttgtatttt tgatggactc tctataaaat tcggtgcaat
    50521 cgtataatcc accttttgtt gatttttaga agtatctact gatttttctt gattatttac
    50581 tttagactca gaagttatgt ttctctcttt gatatatcca atataagtgt agcctgaaat
    50641 ctctttagga agaggtaatt tttctcctgt ggtcaattca tagtcagtat tgtaattcag
    50701 taagagatta ttttctaaag catgagccga tacaagaaca ccatttccta tccctgcaac
    50761 caatactaaa tgtaatactg ttttattctt aacttttttc ttagaaacgg caaaaattaa
    50821 aatccccaga gcagctaagc tagcaccagc aactaaggtt ttcatatcat tcttgcttcc
    50881 agtatttggc aattctccca gttgattttg agaatttaat ttataaacaa gataataagt
    50941 ctcatcatca ttctccatgc atgtcggaat atcatagaca agctgcttct tttcatctga
    51001 tgatagctct gactctgtca catatttata gtgaacacct ttagtctctt gagtctcttg
    51061 agcctctaca gatgaactac ctaatacaga cataaaaaat aaacttgaaa tcgttgcaga
    51121 tacaagtcct actgataatt ttctaaatga aaaacgctgc tgtttttcac caaaatactt
    51181 ttccatgatt cctccttgaa atacaattta tagatgttac aaaaaccttt attatattag
    51241 tgtgttatct ataaaaaatg cagtataatt taattatact attaatttac aaaaaaatct
    51301 taaaattgag ttgcgctttc atactttgtt ttacgtgtaa aatacgaatg cgcagggttt
    51361 gaatttctta tattcttttt ggataaaatg taacctacca tgaaatttcc acggcaggtg
    51421 ttattcatat cactaatcgt tctaaaaatg gtttgatgca gttgaggaga atgccttcta
    51481 tccagctttc ttgtgctgag gagagatgat ctgcttggag gctttctttc agaaaatctc
    51541 gaacttgttc tggtgcgatt tcaaactcaa aagctttcat tttatagaaa aagtcgataa
    51601 gatgatctga tagatattca gttgaaaatg gaacttctcc actttttcga tattctaata
    51661 agagccgagc caatctggat ttttcttcag gaagctcacg aaaataggga ttgaggagcc
    51721 aggtctgctt ctgctttctt tcaattggat cctgactggc tattcgttgg tctttttcca
    51781 actctttttg gtattgtttg gccttgatag cccgttctgt tcgattttta ccaaaaaaaa
    51841 ttttcgccca cttgcgttct tcttgagtca gagtctctgt aaagccaaag taatcttgat
    51901 agacacgctc tgctgggccc atggctagga ctagattgtc tgcatattgc ttggcgattt
    51961 tatccctctt cttgcgctct ttctctgcct ggatacggag ttcttgctcg taatcaattt
    52021 tctccttgcc tagctttaca agatagagtt ggtcatccga tttcccaagt aaaaagggtt
    52081 tgatacactt ttcaagaact tcctccatac gagccttctt cttgggctct gccttggtcc
    52141 aacttcctcc ttgaaagact tctaggaaga gttggtagtc tctctcaggt gagaactgat
    52201 tgccacgatt aggtttaaaa acaccttttt cccagagcca ctttagaagc cgctcgtcaa
    52261 agtcactttt attgaccttg attttttcct ttttctggac ttttttggtc agattttcaa
    52321 cctttctgag cagtttttct tcctcttcta gttgctggtc aaggggcaat cgatgaaaat
    52381 gacgaacaca gtcgctacca atcggaaaga ggcgttggcc tgtgacacca ttaaagagtt
    52441 cgtaggcgta cttgatggca tttccacaga cacaattact acggccgatt ccgttaaaaa
    52501 tcaaggaaac ttcattccat tccttggtag cttgttccca agtatcagct tttgaagcct
    52561 gtaaaaccgc atcgtgcagg gattttctaa ctggaagtgt catgaggtct cctttctaga
    52621 ttatactttt acaacttgaa cctcatcttt accgagtaaa atcaagtatt tttcaatatt
    52681 ttcaatcgaa taggctcgtg ataaagcctc tccgtatagg gctaattgac cacgatagcg
    52741 atctatgagt tgacttggtt catcatagcg gtctgtctta tagtcgaaca gaacgattct
    52801 gccctcgtaa agcagatagc catcaaggat accacgaaca acgaaatctt cctggctctt
    52861 ttggtctcgt ttgagcatgg agaaaggttg ctcgcgatag agatggtcgg tattagcaag
    52921 aatttcctga ccgagtgctg tgtcaaagaa tgcaagaatt ttagcaagat tgatcttgtc
    52981 tctgacagct gggctggttt gaacttgttt gagagtttct gtcaggctag caagcgtcgg
    53041 ttgttgactg aggtcaattc tctgcatgag ttcgtgggta gcactaccaa tctcagctcc
    53101 tgttaccttt tctttgcttg aaaaatctgg taaatcaaag ctaattttct tgtctactga
    53161 ctgaccttga cctgcaatct cgacaccttc catatccata acaggttcgt aaaatttctt
    53221 gatttgactt ggggtttgaa cactaggaag ttcaatagct gcacggtgaa gagtattata
    53281 aacttccact tctttcagca tttccagagc ttctttaata gtttcagact ggcgattgtc
    53341 tgcttgggag ctatcttgga gaggactctt ggttttcaac tctccgatag cttctctggt
    53401 caactgatct tcgccaacaa aacgataact aaagttgagc ttgtccttag taaacacttt
    53461 actgacagcc caaagccaat cttggaaatt ccttgcttgc agtctagtag tgctatttag
    53521 ttttccattt ttagctgctg ggtattcctt ggcttccaac ttttcacgag aacccttacc
    53581 gacaagatag agctttttct cagccctcgt catggcaaca tacagcagac gcatttgctc
    53641 agaatagctt gctagctgta attcttcttc gttctgccta taggtcagac taggaatgga
    53701 gagtttgatg gttttaggat agtggtcttc tactgcccct gtctccatct tggcaatata
    53761 tttgacacca agaccatttt gacgactgag aatgacttct gacatagagt cttgcttgtt
    53821 gaaatcttga tccatattga ggataaagac ataaggaaac tccagccctt tactcttgtg
    53881 gatggtcatg agctctactg catcttttgg cggtgcgacg gccacgcttg ccaaatcgtg
    53941 ctgggcttct aaaacttggt caatcatacc aataaaacgc gacaaacctt tgaaattgct
    54001 cttttcaaat tgatcagcac gcagtgctaa ggcatagaga ttggcctgcc tagcaggacc
    54061 attcggcaaa gccccaacat agtcataata aaaacggtcg ttgtaaatct tccaaatcaa
    54121 gtcatagaga gagtgggttt tggcatacaa gcgccaagaa gctaggatat ccatgaattg
    54181 ctttagtttc tcagctagag ctgtgtgaat taagcctttt tgactacttg ccattttttg
    54241 tgcattgacc agtttctcat agagattttc gtggacttta tcctctgctt tctgaaggga
    54301 caaacgtgct agctcatcct catcgaaacc aaacattgga gacttcataa gggcaaccaa
    54361 ggcgtagtct tgcaggggat tgtgaatgac acgaagggtg tctagcatga cttgcacttc
    54421 tagggattgg agataattgt tttgctctcc gtcagttttg acaggaattc cgtactcaga
    54481 cagggcgagg agaatctggt cattacgact gcggctggag gtcagaaggg caatttcttt
    54541 aaaggcaaca cctttttctt gatgaagttt cagaatctcc ttgataacta agcgcatttc
    54601 gcctgttagt ttcgtttctg cctgcccctc ttcttcctca cctgtgtcgt ccttgtcata
    54661 gaggagaaat tctaccttgt tgtctggatt gggagtcagt ttggtattgg caaaaacaag
    54721 ctggtgcatg ttatcatagt tgatttcgcc gacctcttga tccataagac cttcaaaaac
    54781 atcattggtt gctgatagca cttctgaact actacggaaa ttttctttaa gcaaaatcag
    54841 cttgccttcg tgtggatttt tcgcatagcg ttgaaatttt tcattgaaaa tctgcgggtc
    54901 tgcctgacgg aaacgataga tggactgctt gatatctccc accataaagc gattgtgccc
    54961 attggacaac aattccagca tccgttcttg aatatggttg gtatcctgat actcatcgac
    55021 catgacttcg tggaaacgct cctgataagc ttcacggact tgcgggaatt tctctaaaat
    55081 ctcaatggtg taatggctga tatcagcgaa ttcaaaggca ttttcctgac gtttacgctg
    55141 acgataagcc tccacaaaat cgctcataaa ggtttggaag gttttagcta gtttccaagt
    55201 gtctccatga taacgttctt gatagtcgag aatggttatc tggtctgata attgtcctag
    55261 tttagcaaac tgggtctttc tctcttcgtt gtaggcatca gccaggggct tcaaatcagc
    55321 cttacgactg gcattagtaa gagctcgacc gtttttctcc ttagagatgg cgacaacacg
    55381 cgcaagcact gcctgataag cctgactatc ggactcctga tttagggagc caatttcatc
    55441 cagaattaac tgaacatttt ctaaataggc agcctttgca aactccttgg catcgttatc
    55501 cagatggtaa cggaaaaagc tttccaaatc ccaaagggct tgtttgattt gctcagtcag
    55561 tttttctttt tcactggtaa aatcagcttt ctcaaagcct ttgaggaaag attcactcag
    55621 ccacttttga ggattactgg tggattggag gaagtcatag attttataga cctgctggcg
    55681 cagaccccgt tcgtccttgc catgcccagc aaagtttttc agcaaatgac taaaggtctc
    55741 tttctgttta ccttggtaat gcgcttcaaa gacctcatga aagacttcgt tttcgagaag
    55801 aagttgctcg ctttggtttt gtaaaatacg gaaattaggt gcaatatcaa gcagataacc
    55861 atgtttgcca aggaattttt gtgtgaaaga atccatggtt ccgatggcag cgttgggtag
    55921 gtctgccaac tggcgaccca agtgttgttt gaggtcgaca tcatctgttt cttggatttt
    55981 cttgctgatt tttttctcta aacgttcttt aagttcagtt gcagccttga cggtaaaggt
    56041 tgagataaag agttgagaaa tttcgacacc acgcgccaat tggtccagaa tgcgctctgc
    56101 catgacaaag gtctttccag aaccagccga tgctgagacc aggatattct gaccagaagt
    56161 gtagatagct tcgatttgct cggcagtttt cttctgttcc ttgctcgaat ttgcttctgc
    56221 ttcttgcagt ttttgaatct cctcctcact taaaaaggga ataagcttca tcgattcaac
    56281 tcctctctta ttttttcaag ccaagcttgc ttgagttttt ctccgaccag acgcttgcca
    56341 tcagctaggt ccaacttttc taggaaacgg gcttggccca gatggtaatt ggcttcaaag
    56401 cctgtaatag cctgatgttg ctggacgtat ggggcaatgc ttctgccatt ttcagtataa
    56461 ggattgatgg cgaaccggcc tgctaaaatc ttctcagcag ctttcttgta aagataggca
    56521 ttgtagtcca gtaggagctg aaattcctca tctgtcagtt gattagcctt gtttttgtta
    56581 taaaattcgc ctaaataact gctttctttt tccaagaaga gcccttggta tttcatagat
    56641 ttgctggctt ctaccactgc tcctgccaga ctttttaccg ctatcagaga ttggacaggt
    56701 tcagccattt ccaagtacat ggcgccgaaa aagttctgct ccccttctct ttttagggca
    56761 gcaagatagg ttggtaactg agaattgagc ccattaaaga aatgaggaaa ctggaactga
    56821 gtcagactgg atttgtagtc tactactcct atcgctccat tagctttcaa acggtcaatc
    56881 cggtccacct tgcctcgtac aaagacactg cgtccattgt ctaattgaat aaaggcttgg
    56941 tcttttccac caaaatttgc ttcttctttg atggtttcga tggctggatt gtgtcggaga
    57001 atatgtccag ttgtccgtgc aacatcaagc aaaacttcct tggtaaactg ggcttccaaa
    57061 ctttcttgat aaatagcttc aaattcgcgt tcttgactgg tttcttgaat agcttgttct
    57121 agacgttggt caaaggaatc ttcattaggc aactgcaagg cgcgttcaaa gatacgatgc
    57181 aagaaattcc cgtgactacg ggcatcagga cgcaaacgta attcctcctg caagcctaaa
    57241 acgtagcgta ggaaataact gtattcattg cgataaaact ctgtcaaacc cgacgtagac
    57301 aggtaaaact cctgtttggc aggatagaga gcttgcaagg tgtccttggc taaggtcttg
    57361 ctgcttggac tggttgggat ggctggattt tccagacctt gcagatctag ttttttacct
    57421 atgacacgcg acagaacctt gacaaaagtc aaatcttgct cagtatcgct catctcaccc
    57481 tgctggtgat aggcaaccag actagacaaa agactgtgat aggaccccat atcctcctta
    57541 gacagtcctt tgtgattcat cctcttctct ctccgcctaa atccaaaatg gatcaactct
    57601 tgaagatagg cagattcctt actttcactt tcgttaaaaa ggcttggagc cgacaagaac
    57661 aactgcttac gagcagaatt gaccaaggaa agcatagtgt agcgattttt cttgagattt
    57721 tcactgctgg caatcagtaa ttgaacgcct tcttcggtcg tttggtttag gttttgcctt
    57781 tcttcatctg tcagaagact ggtgttttga gaaatttttg gtaaattgtc ctgagttagt
    57841 ccaatagcat agacaaagtc agcagtcaat ggtgcaatca aatcgtaact ctgcaccaga
    57901 acagtgtcca ctgttgctgg aatggtacgg tattgggaca aactcattcc agaatggagc
    57961 aaggctagga agtcttccag actaacctgt gaaccagcaa aaacagtcgc aaattgttct
    58021 aaaacatggc agaaagcctt ccaaacttcg gcttgtcttt cctgttctac agcttccaaa
    58081 gtggttgtca aatcttgtaa ctgcttggtc acagctcctt cttttagaaa gacactccat
    58141 ttttgtagga ggttttcagc cttttgtttt cggctggcaa agagggtttc aagaggtgct
    58201 aaaattctca ggcggaggac attcaaacgc tcaagattaa attttccatg gtgggatttg
    58261 gtgaagattt gctgaaaggc tggcaagcca ttgataccaa gatagcggat atattgctca
    58321 aaagcatcaa tatcagactg actgaggtca gtatacaagt cagttctaag aagattaatc
    58381 aaatcctcct gacgaaaacg gtaacgtttt aaagctaaaa tagactcgac aaactgagtc
    58441 aagggatgat gagccatggc ttcgcttcta ccaagataaa aaggaatctg atactggtca
    58501 aaaatggttt tgagagataa ctggtaagaa gctacatccc ccaagagaat acgaaaatgc
    58561 ttgtatctca ggtctgagtt ctcatgtaat ttctgacgaa tactacgggc tactagctcc
    58621 aactcctcct tttgcgtcaa acaagaccag atttgtaaat tttcacggtc tttctcatcg
    58681 acatccaaag cgagttctga aaagtcataa gaagactcca acaaacgaga ggccttgtca
    58741 aaactatcca tcttctcatg agtttgagaa cagtcctgag caggcgtttg gtatttagaa
    58801 gccagatgat ggagaaattt tacgctggct tggtagagat tgccctcgct aaaaggactg
    58861 gtataggctt tcttactagc ataagccccg ataacaatct caacaccttt gccgtgaagt
    58921 aagtccacaa cccgctcttc ctcagcagaa aaacgagtaa agccgtcaat gaccaaggcg
    58981 atttgattaa aatcactact taccttgtca ttctcaatag cctcaatcaa atgggacaac
    59041 tgacttccct gggctaactg accttgatta agataggctg ttactttctc aaaaatcaag
    59101 agtaaatccg ccctcttatc ctcatctgtt aaattctcca agtccaaaaa actcatctga
    59161 gatttggtca tctcatggta aagctcaatt aactgctgga tcaattgagg atcctgctta
    59221 atagcgccat aaacacgcaa gtccttggga tcgagttcgg caaggcattt gtaaaaggcc
    59281 aacccaagac cgatatcatc aagagtagtt ttagctggta aatcattcaa gaccagatag
    59341 cgagccattt gagcaaagcg cgtgacggta atcgaaaaag aagcctgctg ggacaagtat
    59401 tccagcacgg cgcgttcctt ttcaaaagaa agagagttgg gggcaatgta gaagacccgc
    59461 ttgccagctg caactagctc ttctgccttt cttgttagaa tttctgtcaa agaagtccga
    59521 atatcagtat aaagtaattt catctcagcc tcgttggaat ttttcatcac cctatattat
    59581 accatgatta tcctcgtaaa tctgttaaaa tatttaggcc atcctttctt ttcttcatca
    59641 tctgctaaat cttaaatact tagctttact tgtattagat agaataagtc tggctactga
    59701 aaatcacata ataaaaaagc ctcggtaaca aggctttgag ttttatgatt gtttcttatt
    59761 aggtacggaa tacacttcaa tgtgttgtcc cagtatctta atgtcgactg gtagattgtc
    59821 tgatttatca ccatcaacat cggactctaa ttcgatatca gaagaagttt taatattacg
    59881 tgcctttata tattcaatat tcttgataga atgattgaac tatagcaaat tgaaactata
    59941 atagtacacc gtggatgcta aaatatttct agaaattaat ttgatttccc taatcaagct
    60001 gttcgtatct tatttcaatc tactatagta aaatgaacca aaaatagtac ataatgtggt
    60061 ataatcgtct tatgggatat tcaatagatt ttcgtaaaaa agttctctct tattgtgagc
    60121 gaacaggtag tataacagaa gcatcacacg ttttccaaat ctcacgtaat accatttatg
    60181 gctggttaaa gctaaaagag aaaacaggag agctaaacca ccaagtaaaa ggaacaaaac
    60241 caagaaaaat tgatagagat agacttaaaa actatcttac tgacaatcca gacacttatt
    60301 tgactgaaat agcttctgaa tttggctgtc atccaactac catccactat gcgctcaaag
    60361 ttatgggcta cactcgaaaa aaaagaacca cacctactat gaacaagacc cagaaaaagt
    60421 agccttattt cttaagaatt ttaatagttt aaagcaccta gcacctgttt agattgacga
    60481 aacaggattc gatacttatt tttatcgaga atatggtcgc tcattaaaag atcagttaat
    60541 aagaggcaaa gtatctggaa gaagatatca gaggatttct ttggttgcag gggctaacaa
    60601 atggtgaatt aatcgttcca atgacttacg aagagacgat gacgagcgac ttttttgaag
    60661 cttggtttca gaattttctc ttaccaacat taaccacacc atcggttatt atggtaaaat
    60721 gaaataagaa taggacaaat cgatcaggat agtcaaatcg atttctaaca atgttttaga
    60781 agtagaggtg tactattcta gtttcaatcc actatattat ggataatgca agattccata
    60841 gaatggggaa gctagaactc ttgtgtgaag agtttgggca taaactttta cctcttcctc
    60901 cctactcacc tgagtacaat cctattgaga aaacatgggc tcatatcaaa aagcacctca
    60961 aaaaggtatt accaagttgc aatacctttt acgaggctct tttgtcttgt tcttgtttca
    61021 attgactata taaattgtct aagcgaaaca accgataaga attggcacaa aagcgaccgt
    61081 atttttgtta ccaatacagg aaaaccagtt catagttcca tcttgagcaa gtcgtctctc
    61141 cagcgagcaa acgaacgcct taaaaaacca attcccaaac atctgtcccc tcacatcttc
    61201 agacacacca ctattagcat cttatcagaa aataaaattc ctttaaaaac aatcacggac
    61261 agggttggtc attccgactc tgaagtcact acttccatct acacctacgt cacaaagaac
    61321 atgaaagatg aagcaatcaa tgtactggat aaagttatga aaaagatttt ttaaaaagtt
    61381 ttgccccttt tttgtcctct aaatacaaaa atagcccttc ggataaaatc cgaggggcta
    61441 gaaacgttgt taaatcaacg accgaacttt tgagtttcaa ggttcgggat aaaatagttc
    61501 actgaactat tttatttttt aaggttgtag aatgatttca atccacgata ttcagctact
    61561 tcaccaagtt ggtcttcgat acgaagcaat tggttgtatt tagcgatgcg gtctgtacgt
    61621 gaaagtgaac cagtcttgat ttgtcctgcg ttagttgcaa ctgcgatatc agcgattgtt
    61681 gaatcttcag tttcacctga acggtgtgat acaacagcag tgtaaccagc ttctttagcc
    61741 atttcgatag cttcaaaagt ttcagtaaga gtaccgattt ggttaacttt gataaggatt
    61801 gagttagcag caccttcttg gataccacgt gcaaggtagt cagtgtttgt tacgaagaag
    61861 tcgtcaccaa caagttgtac tttcttacca agacgttcag taagagcttt ccaaccatcc
    61921 cagtcgtttt catccatacc atcttcaata gtgatgattg ggtatttatt aaccaattct
    61981 tcaaggtagt cgatttgttc tgcagatgta cgaacagcag caccttcacc ttcaaattta
    62041 gtgtagtcgt aaactttacg ttctttatcg tagaattctg atgaagcaca gtcaaatccg
    62101 ataaatacgt ctttacctgg tacatatcca gcagcttcaa tcgcagcaag gatagtttca
    62161 acaccatctt cagttccttc gaaacgagga gcgaatccac cttcgtcacc tacggcagtt
    62221 tccaaaccac gtgatttaag gattttctta agagcgtgga agatttcagc accgtaacga
    62281 agggcttctt taaatgttgg cgcaccaact ggcaagatca tgaactcttg gaaagcgatt
    62341 ggagcgtcag agtgagaacc accgttgatg atgttcatca ttggagttgg aagaacttta
    62401 gtgttgaatc caccaaggta gctgtaaagt gggatttcaa ggtagtcagc agcagcacga
    62461 gctacagcga tagacacacc gaggattgca ttcgcaccca atttaccttt gttaggagta
    62521 ccgtcaagtg cgatcatagc acggtcaata gcttgttgat cacgtacatc gtagccaatg
    62581 atagcttcag caatgatgtt gtttacgttg tcaacagctt tttgtgtacc aagaccaccg
    62641 taacgagatt tgtcaccgtc gcgaagttca actgcttcgt gttcaccagt agaagctcct
    62701 gatggaacca taccacgtcc gaaagcacct gattcagtgt aaacttctac ttcaagtgtt
    62761 gggttaccgc gtgagtctag gacttcgcga gcgtaaacat cagtaataat tgacattttt
    62821 tactctcctt atgagttaaa ttttttacac ctctataata ccttaaaacc cctccttttt
    62881 caagaaaaaa cgttatcttt gtgcaacttt tccttaactt tataaagtaa tcgctttctt
    62941 ttgtctgttt tattctaact tttatgatat actgttttca tgacagattt atcaaaacaa
    63001 ttacttgaaa aagctcatgg tgggttaaaa ataaatccgg atgagcaaag acgctatctt
    63061 ggtacttttg aggaaagagt tcttggatat gtagatattg acacagcaaa tagccctcag
    63121 ttagaaaaag gctttttatt tattttagaa aaccttcagg aaaaagcaga gccactattt
    63181 gtgaagattt caccaactat cgaatttgat aagcaagttt tctacttaaa agaagcaaaa
    63241 gaaactgata gtcaagccac catagtatct gaagagcata ttacttctcc ttttggcctg
    63301 gttattcata gcaatgcacc agttcaagta gaagaaaaag accttcgact tgcttttcca
    63361 aaactttggg aagttaaaaa ggaagaacca gccaaaacat ccttatggaa gaaatggttt
    63421 agctaaatct tgcacatatt taataagtgc ccaatattgg cagccgtgcg ctccagatag
    63481 agactggcat ttttcaaact atcttctaaa ggttcacttt tctccaaaat agaaaagaca
    63541 gcttggatat tttcaaatgg taggggaggt aaatcttcag caagactacc gcaaatagca
    63601 ataacaggaa ctccaacagg ggttcttttt gcaacaccta taggcgcttt cccagcaaag
    63661 ctttgactat caagccttcc ttctccaaca acaaccaagt cagcatctga aactttctta
    63721 ttaaagttga ttaagtccaa gcaggtatca attccagaca ctatacttgc ctgagcaaag
    63781 gcacacaaac caccagcaag gcctccacct gatcctgctc ctttaatttc taatgttgca
    63841 ggtgagaatt tttcataaaa atcttggatc gcctgatcta cgactgcaaa catagtcgga
    63901 tgtagacctt tttgattacc aaaagtgtaa gtcgcacctt gatgaccaca taagggactc
    63961 acgacatctg ctagaatatg aatttgaaca ccttcaggaa ttttatagca attttctgtt
    64021 gaaacagaag ctaagtttaa taaggattga ccggaagcag gcaagacatt tccatcccta
    64081 tcataaaatt gataacctaa accagcagca atccccagtc ctccatcatt actggccgtg
    64141 ccaccaacac cgatataaat atctttaatc cctttagaaa tgagatggag aatcaactct
    64201 ccaataccac aagtttggat ttgaagtgga tttcgcttct ctagcggaat ttttccaaga
    64261 ccaaccaagt cagctacttc aaatagtgcc agttcccctt tttgaaaata gcgcatggct
    64321 tctttttgtc caaaagggtc tgtcacttgg atccattttt cttttaggtc aagagaatgt
    64381 cggatagcat ctacagtacc ttctccccca tcaccaacag ggcagaggag atattctaca
    64441 tctgctatcg attgttggaa gcctcttttt attgcttcag ctacctgttg agctgtcaag
    64501 ctttccttaa acgaatccgg tgcaattaca atcttcatat tttccctcat tctaaacggt
    64561 caatcaaagg aagaacttct aaaaaatccc tcttgtcaac atgatgtggt atttcttttt
    64621 tgagcacttc tttggcacaa aaggcgattc ctaactccgc cgacttcaac attaatagat
    64681 tattaacccc atcaccgatt gccaccgttc tttctttaga aagttttagt ttctttctcc
    64741 atttttccag agtctctttt tt
//
LOCUS       DAVDZK010000006        62732 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVDZK010000006 DAVDZK010000000
VERSION     DAVDZK010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.006"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            167..1423
                     /locus_tag="VUX16_000450"
     CDS             167..1423
                     /locus_tag="VUX16_000450"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET8123483.1"
                     /translation="MHIFDELKDRGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(1501..3564)
                     /locus_tag="VUX16_000451"
     CDS             complement(1501..3564)
                     /locus_tag="VUX16_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET8123484.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRICVTD
                     NQMNSRLLQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLTRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(3566..3844)
                     /locus_tag="VUX16_000452"
     CDS             complement(3566..3844)
                     /locus_tag="VUX16_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123485.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            3996..4844
                     /locus_tag="VUX16_000453"
     CDS             3996..4844
                     /locus_tag="VUX16_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET8123486.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            5467..6039
                     /locus_tag="VUX16_000454"
     CDS             5467..6039
                     /locus_tag="VUX16_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123487.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIHSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGNWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(7084..9342)
                     /gene="glgP"
                     /locus_tag="VUX16_000455"
     CDS             complement(7084..9342)
                     /gene="glgP"
                     /locus_tag="VUX16_000455"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HET8123488.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKLMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(9368..10885)
                     /gene="malQ"
                     /locus_tag="VUX16_000456"
     CDS             complement(9368..10885)
                     /gene="malQ"
                     /locus_tag="VUX16_000456"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET8123489.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            11435..12706
                     /locus_tag="VUX16_000457"
     CDS             11435..12706
                     /locus_tag="VUX16_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET8123490.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKITLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            12817..14109
                     /locus_tag="VUX16_000458"
     CDS             12817..14109
                     /locus_tag="VUX16_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET8123491.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            14111..14953
                     /locus_tag="VUX16_000459"
     CDS             14111..14953
                     /locus_tag="VUX16_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET8123492.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            15214..16014
                     /locus_tag="VUX16_000460"
     CDS             15214..16014
                     /locus_tag="VUX16_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET8123493.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTKELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFKTFKECYHFILNCL
                     GLPTLITLILGLFGQNMSNLITVQNILFVLYLVTIFYKTHFRDPDYHK"
     gene            16024..17010
                     /locus_tag="VUX16_000461"
     CDS             16024..17010
                     /locus_tag="VUX16_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET8123494.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            17146..17226
                     /locus_tag="VUX16_000462"
                     /pseudo
     CDS             17146..17226
                     /locus_tag="VUX16_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(17302..18243)
                     /locus_tag="VUX16_000463"
     CDS             complement(17302..18243)
                     /locus_tag="VUX16_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET8123495.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(18221..19984)
                     /gene="aspS"
                     /locus_tag="VUX16_000464"
     CDS             complement(18221..19984)
                     /gene="aspS"
                     /locus_tag="VUX16_000464"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET8123496.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            complement(20175..20255)
                     /locus_tag="VUX16_000465"
                     /pseudo
     CDS             complement(20175..20255)
                     /locus_tag="VUX16_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(20291..20521)
                     /locus_tag="VUX16_000466"
     CDS             complement(20291..20521)
                     /locus_tag="VUX16_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123497.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFLYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(20539..21180)
                     /locus_tag="VUX16_000467"
     CDS             complement(20539..21180)
                     /locus_tag="VUX16_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET8123498.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(21192..21926)
                     /locus_tag="VUX16_000468"
     CDS             complement(21192..21926)
                     /locus_tag="VUX16_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET8123499.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(21929..22126)
                     /locus_tag="VUX16_000469"
     CDS             complement(21929..22126)
                     /locus_tag="VUX16_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123500.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(22126..22332)
                     /locus_tag="VUX16_000470"
     CDS             complement(22126..22332)
                     /locus_tag="VUX16_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8123501.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(22342..22656)
                     /locus_tag="VUX16_000471"
     CDS             complement(22342..22656)
                     /locus_tag="VUX16_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123502.1"
                     /translation="MWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(22920..22997)
                     /locus_tag="VUX16_000472"
                     /pseudo
     CDS             complement(22920..22997)
                     /locus_tag="VUX16_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(22994..24283)
                     /locus_tag="VUX16_000473"
     CDS             complement(22994..24283)
                     /locus_tag="VUX16_000473"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET8123503.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETISMAAYFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(24361..25608)
                     /locus_tag="VUX16_000474"
     CDS             complement(24361..25608)
                     /locus_tag="VUX16_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET8123504.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMLLPTLFTVFAGIRADYTRAKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGEKLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLCAVLLVNALGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQVCVLLAIIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(25799..26650)
                     /gene="rgg"
                     /locus_tag="VUX16_000475"
     CDS             complement(25799..26650)
                     /gene="rgg"
                     /locus_tag="VUX16_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HET8123505.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            26774..27115
                     /locus_tag="VUX16_000476"
     CDS             26774..27115
                     /locus_tag="VUX16_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET8123506.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            27195..27386
                     /locus_tag="VUX16_000477"
     CDS             27195..27386
                     /locus_tag="VUX16_000477"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123507.1"
                     /translation="MDRTDEVSSKHCFKVVDGTDEVSSKHSFEVVDRTDEVSPKHCFE
                     VVDRTDEVSNHTYGKATLT"
     gene            complement(27412..29115)
                     /gene="ilvD"
                     /locus_tag="VUX16_000478"
     CDS             complement(27412..29115)
                     /gene="ilvD"
                     /locus_tag="VUX16_000478"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET8123508.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMIDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(29348..30280)
                     /locus_tag="VUX16_000479"
     CDS             complement(29348..30280)
                     /locus_tag="VUX16_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET8123509.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(30277..31134)
                     /locus_tag="VUX16_000480"
     CDS             complement(30277..31134)
                     /locus_tag="VUX16_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET8123510.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(31138..32484)
                     /locus_tag="VUX16_000481"
     CDS             complement(31138..32484)
                     /locus_tag="VUX16_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET8123511.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(32497..32781)
                     /locus_tag="VUX16_000482"
     CDS             complement(32497..32781)
                     /locus_tag="VUX16_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET8123512.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(32785..34815)
                     /locus_tag="VUX16_000483"
     CDS             complement(32785..34815)
                     /locus_tag="VUX16_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET8123513.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTDDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            35007..36014
                     /locus_tag="VUX16_000484"
     CDS             35007..36014
                     /locus_tag="VUX16_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET8123514.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGVFIFIMGVGSQNIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKFPFLGAKSSNDNDVNLEISKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQSSAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            36017..36217
                     /locus_tag="VUX16_000485"
     CDS             36017..36217
                     /locus_tag="VUX16_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET8123515.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYASETIDEPFEIDI"
     gene            36369..36551
                     /gene="rpmF"
                     /locus_tag="VUX16_000486"
     CDS             36369..36551
                     /gene="rpmF"
                     /locus_tag="VUX16_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET8123516.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            36567..36716
                     /gene="rpmG"
                     /locus_tag="VUX16_000487"
     CDS             36567..36716
                     /gene="rpmG"
                     /locus_tag="VUX16_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET8123517.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(36846..37229)
                     /locus_tag="VUX16_000488"
     CDS             complement(36846..37229)
                     /locus_tag="VUX16_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123518.1"
                     /translation="MKTKNIEIRRITFSKFEFNTHNTGEVEEDGRASINLNFPDREEG
                     QENQLILIKMEISYPDSQYRVIADIDARYSVLASDLPEDISQDDEFQQALITPMIEKF
                     RLYVGMFSEGAYGAVLIPNLNFNQD"
     gene            complement(37231..37818)
                     /locus_tag="VUX16_000489"
     CDS             complement(37231..37818)
                     /locus_tag="VUX16_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system HicB family antitoxin"
                     /protein_id="HET8123519.1"
                     /translation="MMKDKEYYLGLNYPILIEKIYDEGELLFTASIKELPGLIVYGES
                     LGEVYDEIELAKADWIEANLEWGRKIKEPFENSLEEYSGKITLRLPKTLHRDVKERSE
                     IEGVSLNQTIVQLINDGLFKQTQNAVEQLTEQFKDMTKKLSQTIAEKVSAPEQHIHQT
                     IIIKNQSEKIQPYKEQNITNNRLQDNKVVSWSIGG"
     gene            complement(37805..38062)
                     /locus_tag="VUX16_000490"
     CDS             complement(37805..38062)
                     /locus_tag="VUX16_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HicA family toxin-antitoxin system"
                     /protein_id="HET8123520.1"
                     /translation="MGKEKELQKIKNNPKSVTPERLESLCKKYGFMWKQGTNHSITSH
                     ALLEESYPIPRHKPIKPVYMKKVIKMIEKVIELEEGLNDER"
     gene            complement(38180..38500)
                     /locus_tag="VUX16_000491"
     CDS             complement(38180..38500)
                     /locus_tag="VUX16_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET8123521.1"
                     /translation="MYHTEISMFLRGEASQLAKYNKKSGKPYKDIDDLVDFGRPIHIV
                     PHMFRHSFVSVMAEKNVSLNVIREFVGHSEDSREIEKIYLHVMQKGKDKIEQAMIDLA
                     EIIF"
     gene            38656..38862
                     /locus_tag="VUX16_000492"
                     /pseudo
     CDS             38656..38862
                     /locus_tag="VUX16_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(39025..39294)
                     /locus_tag="VUX16_000493"
     CDS             complement(39025..39294)
                     /locus_tag="VUX16_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123522.1"
                     /translation="MPKTKTLAELADVILWSFDFAIDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREI"
     gene            complement(39681..41561)
                     /locus_tag="VUX16_000494"
     CDS             complement(39681..41561)
                     /locus_tag="VUX16_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET8123523.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVSVAQSDQASISIKGE
                     DGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSVEELQEIEAYAQQFDMTF
                     VPCIQTLPHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDSMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILDGVVNRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(41555..42424)
                     /locus_tag="VUX16_000495"
     CDS             complement(41555..42424)
                     /locus_tag="VUX16_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET8123524.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWHEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMTINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGIKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(42508..45144)
                     /locus_tag="VUX16_000496"
     CDS             complement(42508..45144)
                     /locus_tag="VUX16_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET8123525.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVTAFGRGVKQIGFDNQV
                     LEDEQFTSQFSKMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNRWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHNSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVESLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGYEVLENTARYAKILLKHELTVPVSADEKLEEEQKGIIEFMKREAGRSE
                     ELTNIPLETEFTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPGASWENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASGELG
                     DWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGSVVA
                     TGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLERPY
                     PVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(45335..46602)
                     /locus_tag="VUX16_000497"
                     /pseudo
     CDS             complement(45335..46602)
                     /locus_tag="VUX16_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
     gene            46773..48869
                     /locus_tag="VUX16_000498"
     CDS             46773..48869
                     /locus_tag="VUX16_000498"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET8123526.1"
                     /translation="MKPLLEIIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTGQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADKLTVDQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTNAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWNTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKTCQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYLTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSQPSTS"
     gene            complement(49107..49481)
                     /locus_tag="VUX16_000499"
     CDS             complement(49107..49481)
                     /locus_tag="VUX16_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface anchored protein"
                     /protein_id="HET8123527.1"
                     /translation="MIIQESAKLDAETAKEATDLLADAKKVFADPKASQDEVDAMVKR
                     IEDFMAKVSPATDHTSPAKDQAAQTPAVAPATAQAANANQAAANARTVAKELPNTGTA
                     DSTVAMVVAAASALPWSCRPSS"
     gene            complement(49638..51326)
                     /locus_tag="VUX16_000500"
     CDS             complement(49638..51326)
                     /locus_tag="VUX16_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET8123528.1"
                     /translation="MVREIKPHSPLPSQVQLAYLEDELVAFIHFGPNTFYNQEWGTGQ
                     EDPERFNPTQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSIKVSPWRRG
                     KGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAY
                     GNGGKFAEVWMDGARGEGAQKVNYEFETWFETIRDLQGDCLIFSTEGTSIRWIGNERG
                     YAGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQYPKSL
                     EELVEIYFHSVGRGTPLLLNIPPNKDGLFDAKDVERLYEFAAYRNELYKKDLALGAEI
                     SGSALSVDFACYHLTDGLKTSSGASDVGLPIQLELDLGSPKTFDVIELREDLKLGQRI
                     ATFYVQVEVDDVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYK
                     TPGLSKKEVVQELAFAEKSLAVTKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAY
                     QDEIQVLQFQAGESKKDLSIPTLYFAADKILDFYLNLTVGGQLIDQAHILVETR"
     gene            complement(51328..55057)
                     /locus_tag="VUX16_000501"
                     /pseudo
     CDS             complement(51328..55057)
                     /locus_tag="VUX16_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001250572.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4982 domain-containing protein"
     gene            complement(55295..60124)
                     /locus_tag="VUX16_000502"
     CDS             complement(55295..60124)
                     /locus_tag="VUX16_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET8123529.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMDAQPVQATE
                     TSSTLISSHYLDEQDLSEKLKSELQWFEENKIEVKEGKEYYFVYRKLATRLPETGLFS
                     NDGTFILGAGLLLLSFTLIKRKRGASYFLVTVFAVGGWGASISAFENLVELQPALVKR
                     VEGQFLPSPERVQGYEFTGYYLVRDSSNKELSVDKVESPALSKKEDGSEPQSKKIVPQ
                     TASHFSSTEDFVQSPQPSYAVEKIVEAPVSKQAPDEIVPIGTKEEIAGNPKVEQPKAE
                     NNSDYKPSPEEGVLNATVEKPELLVTTEEIAFQTIEQEDASLAKGQTKVVQEGVVGER
                     TIYTEVTIVNGEKSSKVIENIVTKEPENKVIAVGTKEEVAPKPTQPVTPEPEEVKPVQ
                     PEKIEKKPIVENETETKPAAGIGQPRPGAEETPGEKQTPDKPEAEPKQPELASPAVGS
                     GREEDQSPAEQKGEENQLENPVEGAKDAGESAPQEPQKQPEQTAPSPEVNPSQGNEPA
                     PAVQPEPSAPQEQSDSQVQPTVPSPVTKEKVLDYKTVYTASPALNYKEQQVEVAGENG
                     KEVTTTSYSFDESTGKIVENTSTKIEKHPVDRVVKVGNVEETTSTTKRGEQFVADESL
                     DKGVKEVRNQGQDEETTTIRVYKVNAQTGDLTEPEVSTKVAKEMQAKITAVGTKPTVQ
                     SQEIPFKTVYKASPDLSYNVQQEETPGEKGRTVSTTKYTVNQETGAISEETTIENIPA
                     KDKIVKVGNVEKIVSPIEITELRKDNPELPKGKEEVEDAGEQGETTVTKTYEVNPETG
                     ELTNPVEKTETTKAMRQKVILVGTKEDKPHLLPINSELENAVNVTEATAEMRNVDLLT
                     NEKLKAQLAPSDIEINRDLFLKRKELRKTNPAITDEEVKEILRKEYLEKLSIKETLDA
                     TKTDLEASLKKVAAHTLSILGDNQQNREKVKGDIEANKEKILLGLSYINRFYNIDFGD
                     TNIRDILAYNPSSFGKKDLTSLDWLTYLGSMSYDELRLTNSPKTFEKYFGKITDKPTL
                     LEFLDYNRTTFTNMDGDTWLKKATKAIVVEKPSKQKPDEKVELYTKLTTPPEKYGAEN
                     LQIESRRQQNVAILLGLVNIKEPSVYAITNIATVTYGNIGTYMDTSLEKTNPVKYKEE
                     LEKVKALIELTATRQAAYVDTLYRITKEENRSKLVTNRVIVDTMKKYTADTSAGIGTT
                     WSKESGPTADKGVKDFMTPLGLYSPSQNVGAEANGVGVRYFIDRVLDDRGSATYSHEM
                     THLLDRTVLFNNHGRRDGTAAEFYARGIFENSYTPEKDTYFNLNFVYDESKKNGFYNK
                     TPDRFKTDADLKSYMHGSFDVLYSLDYLEAEATKQLTAEDKTKYFKKITPIASKGPRA
                     TVTYTNSAVKATHKSEKISEITLAEAEKLTDINSLIDNNILVNRYIINGFYATGDVKA
                     NGYYLVDMFDTIYGVSQNDSGMSGDITFRKQAFELMAALGYYEGFVPYVSNQYKQVAE
                     SENKPLSDTYIFNKILNGKSYAEFKKAQFKERVDRLNQLKPLTIQYEGQQISLTSQKL
                     KELMQKAVLAELAQIKAGNTTAQKFEFIETPVQKLKKAIYKAYLKDSDDFRQSIYNS"
     gene            complement(60442..61326)
                     /locus_tag="VUX16_000503"
     CDS             complement(60442..61326)
                     /locus_tag="VUX16_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET8123530.1"
                     /translation="MIFLIVCVFLLLIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     MRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            61583..62440
                     /locus_tag="VUX16_000504"
                     /pseudo
     CDS             61583..62440
                     /locus_tag="VUX16_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520758.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
BASE COUNT        18601 a        13827 c        11351 g        18953 t
ORIGIN      
        1 ttaattcatt taattgattt tgcatggatt tcctcactct atctattata ccacaaaagg
       61 gaaattttca ataaaatagc cactttcttc cctattctgc taggctattg cccaagtttg
      121 tgatacaata ggtagaaaca ataattttaa aaaggagaaa agacacatgc acatttttga
      181 tgagctaaaa gatcgtggtt tgatatttca aacgactgat gaagaagctt tgcgtaaagc
      241 cctagaagaa ggtcaagttt cttattatac tggctacgat ccaactgctg acagccttca
      301 cctaggccac cttgtcgcaa tcttgacaag tcgtcgcttg caactagcag gtcacaaacc
      361 ttatgcgctc gttggcggtg ctacaggtct catcggagat ccgtccttca aagatgctga
      421 acgtagtctc caaacaaaag acacagtaga tggctgggtc aagtctatcc aaggacaact
      481 ttctcgtttt cttgactttg aaaatggcga aaacaaggct gtcatggtca acaactacga
      541 ctggtttggc agcatcagct tcattgactt cctccgtgat attggaaaat acttcacggt
      601 caactacatg atgagtaagg aatctgtaaa aaaacgaatc gaaacaggaa tttcttacac
      661 tgagttcgct taccaaatca tgcaagggta cgacttcttc gtccttaacc aagaccataa
      721 tgtcactctt caaatcggtg gttctgacca gtggggaaat atgacagctg gtaccgaatt
      781 gcttcgtcgt aaagcggaca agactggtca cgttatcact gttccactaa tcacagatgc
      841 aactggtaag aaatttggta aatcagaagg aaatgccgtc tggctcaatc ccgaaaagac
      901 ttctccatac gaaatgtacc aattctggat gaacgtgatg gacgctgacg ctgttcgctt
      961 cttgaaaatc tttactttct tgtcacttga tgagattgaa gatattcgta aacaatttga
     1021 agcagcgcca cacgaacgct tggctcaaaa agtcttggct cgtgaagttg ttacacttgt
     1081 tcacggagaa gaagcctaca aagaagcact taacatcact gagcaactct ttgcaggaaa
     1141 catcaaaaac ctttctgtca aagagctcaa acaaggactt cgtggtgtgc caaactacca
     1201 agtacaggca gacgaaaaca acaatatcgt ggaactgctc gtctcatctg gtatagttaa
     1261 ctcaaaacgc caagcccgtg aagacgtcca aaacggagcc atctacgtaa acggcgaccg
     1321 catccaagag cttgactatg tcttgagtga cgctgataag ttagagaatg aactgactgt
     1381 tatccgtcgt gggaagaaaa aatactttgt attgacttac taaactattc aacatttatc
     1441 tataaacaaa ggagttagcc tcgagaaagg taactccttt ttgctgttaa taactctcat
     1501 ctatctattt ttaatagaca ggctacgcag gacaatgcgc aaggttgtta gattatgtaa
     1561 gatagagaga tttgaaggac tgagccaatt aaataagccg aagccaatca aactactatt
     1621 tacgacaacg gtatcttgaa tatttttctt gatgagtgtt tgcaaagatg atgataacga
     1681 atccaactct tggaagaaat ccaaacgatt atctaacaat aagatatcac tcatctgctt
     1741 agaaatatct gcactctcat tcatcaccac accgatatct gatagagtta aagccgctga
     1801 gtcattcaat ccatctccaa ccatcaaaat agtgtgacct gctttctgca gtttctctac
     1861 taactcaaat ttcccatcag gtttcaagtc tgtatagacc tgatcaaagg gcaaatcttt
     1921 gactaattcc tctgtcctag tcaaggtgtc tcctgttgcc agaatcaatt ttttcccctg
     1981 tgccttaagt ttatccaagg ctgtttttgc ttcttttctc aaaggagtat gaatgcagaa
     2041 cattccaatc aattcatttt gataagccaa gaataagaga ttgtagtgac tcttgtactc
     2101 ttcaattaaa gcattttgtt ctgaactgat atgaatctgc tcatcctgca tcaagacata
     2161 attcccaata agaactggtt ggccatctat atgagatttg atccccttgc ttgcgatata
     2221 ttggagtttc ccatgcattt cctcatgttc aattccctct atctcagctt gcttgacgat
     2281 ggcattagca ataggatgat aaatgtgttc ctcaagacag gcactgattc tgagaatatc
     2341 ttcctcacta tagtctccaa aaggtaacac cttttcaact ataggataac tagttgtgat
     2401 tgttcctgtc ttatcaaaca agaaagtatc aacttccaga tatttctcca gaacatctcc
     2461 atccttaatc accatttcac ggttcaaccc ttccttgata actgtcaaat aagctacagg
     2521 agtagagatt ttcaaagcgc aggagaaatc gaccaatagg aaagaaatag ccttagaaaa
     2581 agaacctgtc aataggtaag tcagcccagc ccccaagaaa ttatatttga cgactttatc
     2641 cgccatcttg atgaaatagc gttgtttcgt tttcttgttt tcttcagatt tcttcatcaa
     2701 ctcaatcagc tgtaaaagac ggctgttcat ctgattatct gttacacaaa tgcgtaactc
     2761 tccagtttct aatactgtat ttgcacaaac caaatcagac tctctttttt caactggaaa
     2821 actctctcct gtcaaggaac tttcgttgac catacctaaa cctgaaacta cttgtccatc
     2881 aaacagaatt tcatttcctt gagataagat caagacatct cctatttgaa catcggaact
     2941 cttgatacta acaaccgtat cgccctgtac taggaataca tcgctctctt ttgcaagaag
     3001 actctgttct aaatctgttg cagttttttt caaggaccac tgatctaaat gattccccaa
     3061 atcaagcata aacatgatat tgctagctgt cttggattgg ttcataaaca aagacaataa
     3121 aatagccgaa cagtccaaga cttccatcgt tagttcctta cgcgctagtg tttgataggc
     3181 ttctctaata taacccaaag cctgataaca agtccatata tagcgaatag gatacggcac
     3241 aaaactacga aaaagtacac gcttaaccgc tgcacctgaa acaatagaat aagcactctc
     3301 ttctctacga atgggaagag tcatcaactc agaaactttc cctttatcaa ttctttttaa
     3361 aaaggcttct gcattatcta atacagaaaa gccttctttt atgcgtagag taaagtgctg
     3421 ttgatccatg taaaactgga tagactcaat ccccttttca tctctcgcca aggaacgaag
     3481 atagtcttga atatccaagg taagtgaaaa agaagatgat agtcggatat gttggtatcc
     3541 tctatgtagc actttaaaag acatattatt cacctataag gctatctaat tgctcttctt
     3601 ttttctcttg ctcgtacaaa tatttggcat cttgcaagac atcgtctcca tgttgcttca
     3661 caacagaaac agatgcatct agctcgtctt tcaacttgta agccttagcc aaagctttag
     3721 aataaccttt tttagcttcc ttacttgcta agattttcaa accaagggta ccaaatgcga
     3781 caccacccaa aaataatgaa gattttttcg caacttttgc aacggttaat acttctttta
     3841 acatacttat ttcctcctta tcattattat atagcaattt agatataaaa gcaatttcat
     3901 tctataaatt ggagaattag ttttatttct actgaatctc ccatctactt attcctaaag
     3961 ttgctttcat ttgcctcttt tgatacactt aaactatgaa tacaaatctc aagcccaaac
     4021 ttcagcgttt tgcttctgcg actgcctttg cctgtcctat ctgtcaagaa aatctgactc
     4081 tgttagagac taatttcaag tgctgcaacc gtcattcttt tgacttggcg aaatttggct
     4141 atgtcaatct agcacctcaa atcaagcaat ctgctaacta taacaaggaa aattttcaaa
     4201 accgtcaaca aatcctagaa gccggctttt accaagctat cttagatgct gtatctgact
     4261 tgcttgcaag ctcaaaaact accacaacaa ttttggatat cggttgtggt gaaggattct
     4321 attctcgcaa actacaagaa agtcactctg aaaaaacttt ctatgccttt gacatctcca
     4381 aagattcagt ccaaatcgct gctaaaagtg aacccaactg ggcagtcaat tggtttgttg
     4441 gcgacttggc acgacttcct ataaaagacg ctaacatgga tattctgctt gatatcttct
     4501 cacctgccaa ctatggagaa tttcgtcgcg ttttatccaa agacggtatc ttgataaagg
     4561 ttatcccaac tgaaaatcac ctcaaagaaa tccgtcaaag agtacaggac cagctgacaa
     4621 acaaggagta ttctaaccaa gatatcaagg agcatttcca ggaacacttt accatcctat
     4681 ctagtcaaac tgcctctctg actaagacta tcacagcaga acaactccaa gccctactca
     4741 gtatgactcc tctcctcttt cacgttgacc agagcaagat tgactggagc caactgacag
     4801 agattaccat cgaagcagag attttggttg ggaaagcatt ctaaactaga cttcccaaag
     4861 gtataaaact taccgaaaat cttcaatatt ataaaaacgc ataagaacag gtacacaaac
     4921 cttaatctta tgcgttttgt tatagtttcc atacacatta aggggaaata gttgaaatca
     4981 gttctcttaa taaccattga ataccatata ctacatttac cccaaatatg atataggccg
     5041 tataaatcaa gtatttcgat ttttcccgcc tcaaagaata gatcttatac aaaataaata
     5101 aatttaaaat aataaataat agagacaaaa tcttcctcca aaatcaatat taaaagtagc
     5161 cagtcaatca tagttctaat ctttattttc gattcgaaat tacaaactta tcaatgaaca
     5221 ataagtgata taaggccagt accagacccc aaacgctacc acgaaaagag aattcttgat
     5281 gattgaaagt aaacaaatca tggttaccaa tatagaggca ggtcaaaata acaaataaaa
     5341 tccaaaataa atccgtccat ttatattttt aaaaatattt ttttaacata atagcatatt
     5401 tttcttgact ataataacag tatataataa aatgtaagca gatacaaata aaaaggagaa
     5461 aagctcatga acaaattaat gaaatttatt tcggtttttt tgacgtcaat tgtgttaatt
     5521 gtatcagcga ttccaagtgt ttcagctgta tacgcttctg aacaagtatc acaaattgaa
     5581 acaaatatgg aacttcaacc tgtcacttct ctaacagaag aacaaatcaa tacacttgca
     5641 aacgaaatcc actcttttca tccagacgtc tcacaacaat ggatcaaaga agtaattaac
     5701 cgacaattac aaggcgatta tacaatccca cctacatact ctccatttag agcagcttgg
     5761 caaggtatta cagttaatca aatgggtgct ctattagata ctgcaatagc tttagcatta
     5821 ggaggaacta ctgcaggcct tgcaaatcta attaaagtaa aaggaaaaca tgcagcaaaa
     5881 agtgctattc gttcagcaat ttctagatat ctaggtaatt ggtttgtaaa tgatgttgct
     5941 ttagaatccg ctatgaattt attatcaccg gggacttatt tagcacaatt atgggataaa
     6001 aatgatgcca ttcctaacaa cggaaggatt aacttttaat catgagatat acaataaaat
     6061 taattgggta taacgtattt tcgttgttta tattctttat cttatcaatg ttgtttaaag
     6121 ttccctttag gtggtggatc agcattgcaa tgacgacttc gtcgtacatt gtatataatt
     6181 acttaaagaa aaagagagaa aaggaatgat cttataccag atcattcctt ttctgctttc
     6241 tgtaaatccc tcggagtgtg tttggcgctt tgatacgaag tgtcaaagct gtataaacgt
     6301 tactatttcc aaaaaagtaa cagaaaattc ctgctttgta ggactgcttt gggtgagtaa
     6361 tagacatgtc gactcaccct atctcctgat ggcgaaaaga atttagcaat ggtgcaagtt
     6421 gttctgaact cgagaaaaaa catgccgaaa tcgaagaaaa gcgtgcagaa cttgaagcga
     6481 agaagcaaga aatgttgaag cgcttggata aatagaattt agaaaacaga aaaaactaaa
     6541 aagaatgtag ggtttatttc cctacattct taaaataact tagtacataa atgacaatgc
     6601 tgccactgcc gtcaatattg caaaaactat tttccaaatt tttttatttt ttccaaaaat
     6661 cttatcaggt aacaagctta ttacaagaaa ggtaataaac aacaccaatt taagtgtgta
     6721 tatcataaaa acaccttctt tcctacaatt atattataat actttatgta agcgaataca
     6781 agagatatga ggtaaccaac tacgaaaaaa tataaggctg aagacagcaa aaaccagcat
     6841 ttaaagcctt cactgtatct aggatttccc tatttttaga caagattgac ccaaatccac
     6901 agcatttaaa aaagcgaatt tcaatcgaaa ctcgcttttt tacaagatgt attagtataa
     6961 atttgtatct tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc
     7021 tcaaagcacc gctttgaggt tgcagataaa gctgacgtgg tttgaagaga ttttcgaaga
     7081 gtattagttc aagtgccaga tgtcttcatt atactgagcg attgtacggt cagatgagaa
     7141 gaatcctgct ttagaaatgt taacgatgac tttatccaac catgcgtcac ggtcttcgta
     7201 gtcagcaagc atttgctctt tgactttgat gtagtcttcc aaatcaagaa gagtcatgaa
     7261 ccagtctttg ttgatcaatt cattgtaaag acgttccaag cgctctttgt ttccagctgc
     7321 aagaactgca tcactaacga tgaagtcaac caatggtttg atagcttcac gagcgtagaa
     7381 ttcgcttgat ttgtaagctg cttttgcgta aaggtcgata acagtttctg aatcttcacc
     7441 gaagatgtag atgttttctt ctccaaccaa ctcagcgatt tccacgttag caccgtccat
     7501 agtaccaagt gtcaaagctc cgttcaacat gagtttcatg ttaccagtac ctgaagcttc
     7561 tttagaagca agtgagattt gttctgagat atcacatgct gggataagga aacttgctgc
     7621 agtaacgttg tagttttcaa ccataactac ttgcaagtgt ggagctactg ctggatcgtt
     7681 agcaataact tctgacatgc aaaggattaa atggataatg tcttgagcga ttgtgtaggc
     7741 tggagctgct ttaccaccaa agaagattgt gattggacga gcagggatgt taccagcttt
     7801 gatgtcaagg tatttgtgga tcacgtacaa agcgttcatt tgttggcgtt tgtactcgtg
     7861 aagacgtttg atttggatat caaagataga atttggattg atttccacac cttggtgttc
     7921 tttcaagtga cgagccaatt tacgtttgtt gtgagccttg atgctttcca atttttcttt
     7981 gacagctgct ttgtcttcat aagacaaaag tttttcaagc tcatctgctt catggtgcca
     8041 accatctcca agaatctcat ccaagtagtg agacaatctt gggttagcat gcataagcca
     8101 acgacggaaa gtgataccgt ttgttttgtt gttgaacttt tctgggtaaa ggtcgtagaa
     8161 ggctttcaac tcagaatttt tcaagatttc agtatggagt gctgcaaccc cgttaacact
     8221 gtatccgtag tggatatcca tgtgagccat gtgaacacgt ccgctctcat cgatgatttg
     8281 aacagctgga tctttgtact ctgccttcac acgacggtcc aattcttcga tgattggtac
     8341 caagtgagga accacttctt gcaagaattc aagaggccat ttttcaagcg cctcagcaag
     8401 gattgtgtgg ttagtgtagg cagtcatgct acgaacaatt gagattgctt cgtcaagctc
     8461 gataccacgt gcagtcaaaa gacgaatcaa ttcaggaatc accattgatg ggtgagtatc
     8521 gttgatttgg acaactgcgt agtcagcaag gtcatgcaag ttgcttcctt tttcgattgc
     8581 ttcgtcgatg atcaattgcg caccgtttga aaccatgaag tattgttgga agatacggag
     8641 caattcacct tgacggtcac tatcatctgg gtaaaggaag agagtcaagt tgcgagcgat
     8701 atctgtcttg tcaaagttga taccatcttt aataatagaa gaatcaactg aatccaagtc
     8761 aaacaaacgc aagcggtttt tagtcgctgt ttcataacca gtaacatcaa tatcgtaaag
     8821 agttgatgtc aaagtaaagt ctgcaaatgg tacttggtag ctacggcttg agcgaaccaa
     8881 ccagttttgc tctgtcaacc atgcatttgg aattgtttct tgttggttgt ttttaagaac
     8941 ttgttggaaa agaccaaagt ggtagttaag accaacaccg tcaccattca aaccaagagt
     9001 agcaattgag tcgataaagc aggcagccaa acgtcccaaa ccaccattac caagagatgg
     9061 ttccaattca acttcttcaa cttcgatcaa gtctttacct gcagctgcaa gttctttttt
     9121 aacatcgtcg taaagaccaa ggttaatcaa gttgtttgac aagagtttac caatcaagaa
     9181 ctcagctgag atgtagtaaa cttttttctt accagtgttg actggttttt ggctgcttgc
     9241 aagcttgctg tagttaagaa gagcaaggta aagctcttca ttgctacatt ctgcaatggt
     9301 tttattgtaa cgattttgta caaattcttg tagtgataac atgtttagtt gtctcctgat
     9361 tattgtctta tttctttaaa tctaccaaat tttcattaat tcggcgataa attgttgtca
     9421 agtcaagcaa accttcctcg acagctggtg tcaattgatc ttcagtcata cgccaagacc
     9481 agtttccacc aagggtagat gggaagttca tacgagctgc ctcatccaat tctagtaaat
     9541 cttgcatagt cgcaattgcc ataaagctaa ctgatgaaaa tactgtacga agcatagcgt
     9601 gtaccactgt ttcgtattct ttacggttcg tgtaacgagc catgtactca cgagtcgcat
     9661 catcaatctc attacggtac caaccaagaa ccgtattgtt atcgtgtgtt cctgtgtaca
     9721 taactgagtt agcaggtgcc aagtgtgggc tatcaatgct ttcgtcttct gggttgaagg
     9781 caaattgaag aatcttcatt cctgggaagc cagtacgttc acgcaattcg atcacttcat
     9841 ctgtcatgaa gccaaggtct tctgcgatga tgtttagctc accaagttct tccttaacgg
     9901 ctgcaaaaag cttgtagcct ggacctttca cccactcacc aggtgctgct gtatcggaac
     9961 cagcagggat ttcccaataa gattcgaagc cacggaagtg gtcgatacga acgatatcgt
    10021 agattttgaa gctttcacgc aagcgttcaa tccaccattt gtagccgtct ttgtccattg
    10081 cttcccagtc atagattggg ttaccccaaa gctgaccagt tacagaaaac tcatctggtg
    10141 ggcatcctgc gatacaagta gccttaccat tgacatctgt tttgaagaga tgtggatttg
    10201 cccacatatc acttgaatct tccgctacgt agattggcat gtccccaacg atttcaatgt
    10261 ggttgtcgtt agcgtaagct ttcaatttca accattgttg gaagaagaag tattgagtca
    10321 cacggtggta aaccaacttg tctgccaatt gctcacgata gctttcaagt gctgaagctt
    10381 tacgagcacg agcatctgca tctggccatt cagtccaagc aagattgtca aaatgctctt
    10441 tgatagccat atactcagca aagagctcaa gccatgattg gttgtcttga gcaaatttct
    10501 caaaatcttt aacatctccg acttcaaaga aacgtttcac cgctttttct aaaagaggac
    10561 gacgtgcata gtagatttta gcatagtcaa cttcagacgc atcgctacca aagtcaactc
    10621 cttcaaggtc acttgcttcc aacaaacctt gctccaccaa gatatctaaa tcgataaaat
    10681 gagtgtttcc tgcgaaggct gagaaagatt ggtaaggaga gtccccgtaa ctagttgctc
    10741 ctaatggaag gatttgccag taacgttgtt ttgtacggac caagaaatca acgaagtcgt
    10801 aagcactttg accaaatgat ccgattccgt aagctcctgg aagagaagag atgtgcatca
    10861 acacaccact ttgacgtttt ttcataatag cacctcgtgt gttaaaataa tggaacgttg
    10921 cgtattttgc agacgcaaac gtttgcgtta cttataagta tactcctttt caagcataat
    10981 tgcaagcgtt tttaaaaaac ttttttgatt atttttaagg agactaactc attttagcaa
    11041 agataactta aaactatcta atcctaaagt ttgactctca cgagacagtc tacaaagtac
    11101 aaaacctcct tagggagctt gaatttatat gcaacaaagc acaaacgtct atagaaaata
    11161 gatagggatt agaaccaggg aggtagcccc tcctggtttc cctctttaga cagattccat
    11221 atatttttat taaaaatact gtattcttat ctatttcata cttttcttct attaaaatgc
    11281 aaaattatgc tatcaaatca agcttaaaaa ttttttaaaa tttttacaaa aaatacttgc
    11341 aaccgttttc tatttgtgct atactaagct cataaaggaa aacgtttgcg tttccttatc
    11401 aataaaactt gctattcttt gggaggaata cactatgtca tctaaattta tgaagagcac
    11461 tgcggtgctt gggactgtta cacttgctag cttgcttttg gtagcttgcg gaagcaaaac
    11521 tgctgataag cctgctgatt ctggttcatc tgaagtcaaa gaactcactg tatatgtaga
    11581 cgagggatat aagagctata ttgaagaggt tgctaaagct tatgaaaaag aagctggagt
    11641 aaaaatcact cttaaaactg gtgatgctct aggaggtctt gataaacttt ctcttgacaa
    11701 ccaatctggt aatgtccctg atgttatgat ggctccatac gaccgtgtag gtagccttgg
    11761 ttctgacgga caactttcag aagtgaaatt gagcgatggt gctaaaacag acgacacaac
    11821 taaatctctt gtaacagctg ctaatggtaa agtttacggt gctcctgccg ttatcgagtc
    11881 acttgttatg tactacaaca aagacttggt aaaagacgct ccaaaaacat ttgctgactt
    11941 ggaaaacctt gctaaagata gcaaatacgc attcgctggt gaagatggta aaactactgc
    12001 cttcctagct gactggacaa acttctacta tacatatgga cttcttgccg gtaacggtgc
    12061 ttacgtcttt ggccaaaacg gtaaagacgc taaagacatc ggtcttgcaa acgacggttc
    12121 tatcgtaggt atcaactacg ctaaatcttg gtacgaaaaa tggcctaaag gtatgcaaga
    12181 tacagaaggt gctggaaact taatccaaac tcaattccaa gaaggtaaaa cagctgctat
    12241 catcgacgga ccttggaaag ctcaagcctt taaagatgct aaagtaaact acggagttgc
    12301 aactatccca actcttccaa atggaaaaga atatgctgca ttcggtggtg gtaaagcttg
    12361 ggtcattcct caagccgtta agaaccttga agcttctcaa aaatttgtag acttccttgt
    12421 tgcaactgaa caacaaaaag tattatatga taagactaac gaaatcccag ctaatactga
    12481 ggctcgttca tacgctgaag gtaaaaacga tgagttgaca acagctgtta tcaaacagtt
    12541 caagaacact caaccactgc caaacatctc tcaaatgtct gcagtttggg atccagcgaa
    12601 aaatatgctc tttgatgctg taagtggtca aaaagatgct aaaacagctg ctaacgatgc
    12661 tgtaacattg atcaaagaaa caatcaaaca aaaatttggt gaataaaaaa tttgttcaag
    12721 gggggtggaa atcaaatccc cctttgaatt tatcaataga gacacaaata atttagcttt
    12781 cttataaaaa agtagtatcc tatgaaagga gttaatatgg aaaagcaaca acctagtaaa
    12841 gcagccctgc tgtctatcat tcctgggtta ggacagattt acaataaaca aaaagccaaa
    12901 ggttttatct tccttggtgt aaccatcgta tttgtccttt acttcctagc acttgcaacc
    12961 cctgaattga gcaacctcat cactcttggt gacaaaccag gtcgtgataa ttccctcttt
    13021 atgctgattc gtggtgcctt ccatctaatc tttgtaatcg tttatgtact cttttatttc
    13081 tcaaatatca aagatgcaca tacgattgca aaacgcatta acaatggaat tccagttcca
    13141 cgcacactca aagacatgat caaagggatt tatgaaaatg gcttccctta cctcttgatc
    13201 attccatctt atgttgccat gaccttcgcg attatcttcc cagttatcgt aaccttgatg
    13261 atcgccttta ccaactacga cttccaacac ttgccaccaa acaagttgtt ggactgggtt
    13321 ggtttgacca actttacaaa catttggagc ttgagtacct tccgttctgc ctttggttct
    13381 gttctttctt ggactatcat ttgggctttg gcagcttcta ctttacaaat cgtaattggt
    13441 atcttcacag ctatcattgc taaccaacca tttatcaaag gaaaacgtat ctttggtgtt
    13501 attttccttc ttccttgggc tgtcccagcc ttcatcacta tcttgacatt ctcaaacatg
    13561 tttaacgata gtgtcggtgc tatcaacact caagtattgc caatcttggc taaattcctt
    13621 cctttccttg atggagctct tattccttgg aaaacagacc caacttggac taagattgcc
    13681 ttgattatga tgcaaggttg gctcggattc ccatacatct acgttctgac cttgggtatc
    13741 ttgcaatcta ttcctaacga cctttacgaa gcagcttata ttgacggtgc caacgcttgg
    13801 caaaaattcc gcaacatcac tttcccaatg atcttggctg ttgcggcacc tactttgatt
    13861 agccaataca ccttcaactt taacaacttc tctatcatgt acctcttcaa tggtggagga
    13921 cctggtagtg tcggaggtgg agctggttca accgatatct tgatctcatg gatctaccgt
    13981 ttgacaacag gtacatctcc tcaatactca atggcggcag ctgttacctt gatcatctct
    14041 atcattgtca tttcaatctc tatgatcgca ttcaagaaac tacacgcatt tgatatggag
    14101 gacgtctaag atgaataact caattaaact caaacgtaga ctgactcaaa gccttactta
    14161 cctttacctg attggtctat caattgtaat tatctatcca ctgttgatta ccattatgtc
    14221 agcctttaaa gcaggtaacg tctcagcctt taaactagat actaatatcg acctcaattt
    14281 tgataacttt aaaggcctct tcactgaaac cttgtacggt acttggtacc tcaacacttt
    14341 gattatcgcc ttaattacca tggctgttca aacaagtatc atcgtacttg ctggttatgc
    14401 ttacagccgt tacaacttct tggctcgtaa acaaagtttg gtcttcttct tgatcatcca
    14461 aatggtgcca actatggccg ctttgacagc cttcttcgtt atggcgctta tgttgaacgc
    14521 ccttaaccac aactggttcc tcatcttcct ctacgttggt ggtggtatcc cgatgaatgc
    14581 ttggctcatg aaaggctact tcgatacagt gccaatgtct ttagacgaat ctgcaaaact
    14641 agacggtgca ggacacttcc gccgcttctg gcaaattgtt cttccacttg ttcgcccaat
    14701 ggttgccgta caagctctct gggccttcat gggacctttc ggggactaca tcctctctag
    14761 tttcttgctt cgtgagaaag aatactttac tgttgccgta ggtctccaaa ccttcgttaa
    14821 caatgcgaaa aacttgaaga ttgcctactt ctcagcaggt gctatcctca tcgcccttcc
    14881 aatctgtatt ctcttcttct tcctacaaaa gaactttgtt tcaggactta caagtggtgg
    14941 cgacaaggga taatttatcc ccaccaccct ttttcatttt atactcttcg aaaatctctt
    15001 caaaccacgt cagctttatc tccaacctca aagttgtgct ttgagcaacc tgcggctagc
    15061 ttcctagttt gcactttgat tttcattgac tattagcgat tgtcactgta aataatatcc
    15121 ttgtagcaag caatttaccc cctagacttg aaataaagcg catttctcta tataataata
    15181 ctcatataga aaacaccttt tagaaagata cctatgcttc catatccatt ttcctatttt
    15241 tcaagtattt gggggtttcg taagcccctg tccaaacgtt tcgggctcaa ctggtttcaa
    15301 cttctcttta ccagtatctt ccttatcagc ttgtctatgg tacccattgc tatccaaaac
    15361 agctcccagg agacctatcc gctagaaact tttatcgata atgtctatga acctctgaca
    15421 gataaggttg tccaggatct ctctgaacat gctacaattg tcgatggcac attaacttat
    15481 actggaacag ctagtcaagc cccttctgtt gtgattggtc caagtcaaat caaggaatta
    15541 cctaaggact tgcaactgca tttcgacaca aaagaactgg tcatcagcaa ggaaagcaag
    15601 gaattgaccc gtatctctta ccgagcgatt cagactgaga gtttcaaaag taaagacagc
    15661 ttgacccaag caatttctaa agactggtac caacagaatc gtgtctatat cagtctcttc
    15721 ctagttctcg gtgcgagctt cctctttggt ttgaatttct ttatcgtctc tctaggggcg
    15781 agtcttctcc tttatatcac taagaaatca cgcctctttt catttaaaac ctttaaagag
    15841 tgctaccatt ttatcttgaa ctgtttagga ttgccgactc tgattacgct tattttggga
    15901 ttgtttggcc aaaatatgtc aaacctcatc actgtacaaa acattctttt tgtcctttat
    15961 ctggtcacta tcttttataa aacgcatttc cgtgatccag attaccataa ataggagatt
    16021 tttatgcccg ttacgattaa agacgtggcc aaggctgctg gtgtttcccc ttcaaccgta
    16081 acccgtgtta ttcaaaataa atcaaccatt agcgacgaaa ctaaaaaacg cgttcgcaag
    16141 gcgatgaagg agctcaatta ccaccccaac ctcaatgctc gtagcttggt aagcagctat
    16201 actcaggtga ttggtttggt tcttcctgat gactcagacg ccttctatca aaatcctttc
    16261 ttcccatcag tcctacgcgg catctctcaa gtcgcatctg aaaaccacta tgccattcag
    16321 atagcaacag ggaaagatga gaaggagcgt ctcaacgcta tttcacaaat ggtctacggc
    16381 aagcgtgtag atgggctaat ctttctctat gcccaagaag aagaccctct cgtaaaactc
    16441 gtcgcagaag aacagttccc cttccttatc ctaggtaaat ctctatctcc tttcatccca
    16501 cttgtcgaca acgacaatgt tcaagctggt tttgatgcga ctgaatattt catcaaaaaa
    16561 ggctgcaaac gcattgcctt tatcggagga agtaaaaagc tcttcgtgac caaagaccgt
    16621 ttaacaggct atgaacaggc gcttaaacat tacaaactta ccactgacaa caatcgcatc
    16681 tactttgccg acgagtttct ggaagaaaag ggctataaat ttagcaagcg attattcaag
    16741 cacgatccac aaattgatgc tatcatcaca accgatagcc tcctagctga aggtgtttgt
    16801 aactatattg ccaaacacca gctggatgtc cctgttctca gctttgactc ggttaatccc
    16861 aagctcaact tggcagccta tgtcgatatc aatagtttag agcttggtcg tgtttccctt
    16921 gaaactattc tccagattat taatgataat aaaaacaata aacaaatttg ttaccgtcaa
    16981 ttgatcgccc acaaaattat cgaaaaataa aagactgggc aaagagtcgt taaaagcaaa
    17041 aacgcatact atcaggtatt gaaaaaactt gatactatgc gttttattgt gggaagattt
    17101 acttcctttt ctactgaaat tgagtctttt cccaagatct ttttatactc aatgaaaatc
    17161 aaagtgcaaa ctaggaagct agccgcaggt tgctcaaaac actgttttga ggttgtggat
    17221 agaactgacg aagtcagtaa ccatacctac ggcaaggcga cgctgacgtg gtttgaagag
    17281 attttcgaag agtattaatc actaattatc tatctcaaca aatcttccta gaatatgaac
    17341 attttccgag acagagacaa aggagcttgg atccacttgt gtcataatct gtttaaattc
    17401 attaaactct gcacgtgtaa tgacagtgat taaaactgcc tttctctcgt gattataggt
    17461 tccttctgca tcgtggatca tggttgctcc gcggtgcaat tttttatgga ttttttcaat
    17521 taccttctct ggatgatttg tcacaatcat ggcctgcata cgcttttgct tagtaaagac
    17581 tgcgtctgtc acacggctag agacaaagat ggtaatcata gaataaagag cgtatttcca
    17641 accaaaggtc aaacctgcta tcagcatgat agttccattt accaagaaag aaatactacc
    17701 gacattctta cccgttttct tgcgaatagt caggctgacg atatccgtcc caccactgga
    17761 gatattgttt cgaagagcaa aaccaatccc caaacccata acaacacccc caaaaaggga
    17821 attgataatg ggatcctccg tcaaggttgc cacagggaca aactggataa agaaggaact
    17881 catagatacc gtgataaagg taaagacggt gaacttatgg ccaatctgat accaagctaa
    17941 gaccatcaaa gggaagttaa tggcgtagaa gcttagcgaa atcggaatat gaaaaccaaa
    18001 ccagtgatta ctcaaggcag agataatctg tgccagacct gttgcaccac tcgaatacac
    18061 atgccctggt tggaaaaaga aattaactgc tactgctgat aaaaaaccat agaccagaga
    18121 ggccgaaatc ttctcatcat acttttctcg agagatactt tgtaagacac gtaaaatttt
    18181 tatctgataa gcaaagcggc gcagataata gcgccaccgc ttaattcgtt ttgtttgttt
    18241 catcttcttc tacttgtaag ctgagttcct ctagttgttt gagagcgact gttgatggag
    18301 cttgtgtcat tgggtcagtt gccttgttgt tcttaggaaa ggcaatgact tcacggatat
    18361 tttcttctcc agcaagcaac atgacaaagc ggtcaagccc gatagccaaa ccaccgtgtg
    18421 gtgggaaacc atagtccatg gcttcaagaa ggaaaccaaa ctggtcattg gcttcttcag
    18481 ttgagaaacc aagagccttg aacatgcgtt cttgaaggtc tttttggttg atacgaaggc
    18541 taccaccacc aagctcataa ccgttcaaga cgatatcgta agcaatggca cgaaccttag
    18601 ccaaatcacc ttctaattcg tgagcagtct cttcctgtgg aagtgtgaat ggatggtggg
    18661 cgctcatgta gcggccttct tcttcagacc attcaaacat cggccagtca accacccaaa
    18721 ggaagttgaa cttatcatta tcaatcaagc caagctcttt agcaatacgt ccacgaaggg
    18781 cacccagtgt tgcattagcc acttcaagcg tatccgccac aaagagaacc aagtccttat
    18841 cttcaagagc aagcgctgtt gtcaattctt cttggatacc agtcaagaac ttggcaactg
    18901 gtccgtttaa ttctccatca accaccttga cccaagcaag acctttggca ccatactgtt
    18961 tggctacttc cgtcatcttg tcgatgtctt tacgtgaata gttgtccgca gctcctttga
    19021 ccacaatcgc ttttacagca ggtgcttctg aaaagacttt aaagtctaca cctttgacca
    19081 cttctgtcaa gtcctgaagc aacatgtcaa aacgagtatc tggcttgtca gaaccgtaaa
    19141 gagccatagc atcatcgtat ttcatacgag ggaacggtag cgttacttcg atgccttttg
    19201 tttccttcat cacgcgcgcg atcaagcctt ctgtaatatc ttggatttct tgctcagtaa
    19261 ggaaggacgt ttccaagtcg acctgagtaa attcaggctg gcggtctcca cgcaagtcct
    19321 cgtcacggaa acatttaacg atttggtagt aacggtcaaa accagcattc atcaagagct
    19381 gtttcgtgat ttgtggactt tgaggaagag cgtaaaaatg ccccttatta acacgagacg
    19441 gcactaaata atcacgcgcc ccttcaggcg ttgacttaga aaggaatggt gtctccacgt
    19501 cgataaactc caactcatcc aaatagttgc ggatagagtg ggtcaccttg gcacgaagtt
    19561 taagattttc caacatttct ggacgacgaa ggtcaaggta acggtaacgc aaacgtgtat
    19621 cgtcatttgc ctcaatgcca tccttaatct caaatggtgt tgtcttagct gtgttaagca
    19681 caataagagc tgtcacgttt aactcaaccg caccagttgg caacttatca ttggcttgct
    19741 cacgcgcagc gacctgacca gtcacctcaa taacaaattc gctacgaagg ctttcagctg
    19801 ttgccataac ctctgcagat actttttcag ggttgataac caactgcatg attccttcac
    19861 ggtcacgaag atcgataaag atcaaaccac caaggtcacg acgacggcca acccatcctt
    19921 tcaaggttat ttcttgtccg atgtgttcct cacgaacacg accagcatac atactacgtt
    19981 tcattatttc tctcctcttt tattctgtta ctattttacc ataaaagcgc aggctcttca
    20041 tgaaaatcat cagaaaagtt tgccagtctt taaaagtcag gtgaaagccc taaaaattag
    20101 cgctaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtaggtatgg
    20161 ttactgactt cgtcagttct atccacaacc tcaaaacagt gttttgagca acctgcggtt
    20221 agcttcctag tttgctcttt gattttcatt gagtataata caaaaatccg atgaacttca
    20281 ccggactctt ttattttgaa tttttgcctg ctttacgctt ttcagcgatt tcggctgcct
    20341 ttcgaggcaa gacaatttcc gttatgtaag ccgtcccaaa acgcagtaca cctgcaatag
    20401 gagcaaagac aactgctaga tagttataga ggaaatcgcc tttgaaggca taagctagcg
    20461 ctccaatgat gaaaaataga acgactgcct gaatcactgc tactaaaatt actcgtttca
    20521 tgtgacctcc tgactctatt atagcatgag aatcatcaaa aagccgacta aattattcaa
    20581 agcgtgaaga gaaatactgt agaccagacc ttttctgcta atgtaagcca aacccaaact
    20641 aaaaccaagg ctaaaataga caaaaaattg ttgcacatca cctggaaaat gaatcaaggc
    20701 aaatagaaga ctagatacca gaagaaaaat cagggttcgt ttactattgt cctgcttagg
    20761 aaagagatag cgtgctaaca tccctctaaa aacaatctct tccgtcaaag gagcaaaaat
    20821 aaccacagca aagaatgaga aaagtggttg agacaaggtc aagtctgtcg ctatttgttg
    20881 atttactgaa ggatcatctg gcaagaagaa ttgaacgacc agagataaga accaaaccaa
    20941 ggcaggaagc caaataaatc ggttaaagcc gctcttctca atataaacag gagctttctg
    21001 ataccatttg taaatgccgt acacatatac tccagccaag accacataga gtagagtaac
    21061 agcatagggt gaagcgccta aagcaagcga cgcagtcgcg agcccctgaa taaagccata
    21121 gataaagaaa aaggatagaa gggctagaag aaaccagcca aggtttttaa gtagtttcat
    21181 agataactcc tttatttgaa ataacgtttt accataggta actgcatcac attgatataa
    21241 acatggatgg ctcctacaag caagaaagct agtaactgaa tctctcctgt caagaaagaa
    21301 atgataataa gaaaaatata taaggctggt aagacatatt ggtgtaattg gaataaaatt
    21361 cgaaaactct gttccaaatt agcctgacgc tccccttcat cataagaatt tatatagttc
    21421 aagacatcct ttggtgtagc gaaaaattcc aaatcaaact gacgaacaat cgcaatggtt
    21481 ttaaaaagag atttttgagc gactaagaat accacaaaga gtaagaaaga aaggaaaaat
    21541 gtttgagggt ttgtatgcaa tataatcacc tcacttaatg aaataaaaat agccaatgga
    21601 atcgctacac ctgtaatatt aaaagcaatg gttccaaact caagattccg atacatttgc
    21661 acataatagg tttcattcag atcgtcatcc atttcctctt gatacaagga atgaaatttt
    21721 ctgcttttct ttaagaaatt gaaagtcaaa aacatactaa tgaaacctat cagtaaacaa
    21781 atagctgata tccatggcat caaggctttt acatctaaaa taatttcgtg ggattcgaca
    21841 cgtgccttaa acatccctac aaacatgccc aagaaccccc ccaagacaat agacatcaaa
    21901 aataacaatc tacgtttctt tttcatattc attctccttt ttcacttgct agatttttgg
    21961 atttcttttc aatccattca attactggga tgagagcaaa gtagacccaa acaaattggt
    22021 cgctttgata gggattaaac cagcttaggt ccatcccaat cagtagaaat acgctgacta
    22081 ataaagctat gaccactaca taataaatca ctttatactt gttcatcact cgtcctcctc
    22141 caaacgaaat accgattcga ctgtttcgtt gaaaatttga gatattttca gggcaatgat
    22201 aatggatggg gtgtactcat cccgttctag taggctaatg gtctgtctgg aaacccctgc
    22261 cagtttggct aggtcggttt gattgagacc atcgcgagct cgaagctctt ttagacgatt
    22321 ttttagttgc atgttacaca cctactctcc gtcaaattca acggtttgga tatcctcaat
    22381 acgttgcaac ttgaattttt cttttcccgt attatctaca cgtcgtagct ttacccattc
    22441 ctcatcaaca tccacaactt cccagttatc tggcccaata tacactcccg ttataattgg
    22501 ttcctttcca atcatttctt gtaataatct cgacatttct gcatttcctt tctcttttcg
    22561 ctcaagtctt ttgattttct tctctagttt cttgattttt ttagaatcat tagaataaaa
    22621 gaaaatcaga aatagtataa accctagtac ccacatcata gctcctttct tcttttctct
    22681 taacttgctt acattgtaac acatcttttt ctttttgaca agtatagttg tcaaaaagtt
    22741 tatgattttt gtcattttgc aaaagaaaaa ggtcaggagt aagttcctga ccactttatc
    22801 tatcattaat actcttctaa aatatcttca aaccacgtca gcttcacctt gccgtaggta
    22861 tggttactga cttcgtcagt ttcatctaca acctcaaaac catgttttga gctgacttcg
    22921 tcagttctat ccacaacctc aaaacagtgt tttgagcaac ctgcggctag cttcctagtt
    22981 tgctctttga ttttcattga gtataaaatc ctagtttttc aaagatttct gagaagtttt
    23041 ggctgattgt ctcaagtgac acttgcactt cttctcgggt ttggttgttc ttgaccgtca
    23101 cttgtccgct ttcgacttcg ctctctccta gggtgatgag ggtcttagcc gcaaagacat
    23161 ctgctgactt gaactgagct ttgagcttac ggttgaggta atcacgctct gctttgaaac
    23221 cttgttggcg aagagcttgg actagttcta gggctttgac atttgctcca tcacccaaga
    23281 ctgcgatata gacatctagg gcgttttcga tagggagggc cacgccttgt ttttcaagga
    23341 tgagaagcag gcgctctaca ccaagcccaa aaccaaatcc agcagtttca gggcctccaa
    23401 agtaagcaac caaaccatcg tagcgaccac ccgcacagac tgtcaagtca ttgccctcaa
    23461 tctctgtgat aaactcgaaa atggtgtggt tgtagtagtc cagaccacgc accatattgg
    23521 tatcgatgat gtaatctact ccaagatttt ccaacatctg acgcacagca tcaaaatgag
    23581 tttggctttc ttcatcaaga aagtccaaga tagacggcgc attctctact gccaccttgt
    23641 cttctttttc cttagagtcc aagacacgaa gaggattttc ctccaagcga cgttggctat
    23701 ccttagacaa ggtctccttg agcggtgtca aatagtcaat caaggcttgg cggtaggctg
    23761 cacggctctc aggatttcca agagtgttga ggtgcaattt gacaccttga ataccgattt
    23821 ccttcaaaaa ataggctgcc atagagattg tttccacatc ggtagctgga ttgctagagc
    23881 caaaacactc aacaccaatc tggtggaatt ggcgcaagcg ccctgcctgt ggacgctcat
    23941 aacggaacat aggtcccata tagtagaact tgcttggctt ttgcacttct ggggcgaaga
    24001 gtttattttc cacataggaa cggacaacgg gcgcagttcc ttctggacgg agggtaatat
    24061 gacggtcacc cttgtcataa aaatcgtaca tttccttggt tacgatatcc gttgtatctc
    24121 cgacagagcg actgataacc tcgtaatgct caaaaatagg cgtgcgcact tctgcatagt
    24181 tatagcgctt gaaaatctca cgggcaaagc cctcaacgta ctgccactta gcagattcag
    24241 caggtaaaat atcctgcgtt ccttttggtt tttgtaattt catagggaat cctctttaaa
    24301 cttaatagtc ttattttacc acaaataaag ggattaaaac agtaagaaaa aaattaggat
    24361 ttagatatca tttttgagat taagaattgt caaaaaaata gctagcaagg aaagaccaac
    24421 aaatagcatc caagtcaact gtatattcca tacggctact agtgaaaaac aagctgttcc
    24481 cacaggtatg gataaggtaa acaatagacc taaaaaatta ctagtacgag ctagaacctc
    24541 tggagctaga tttttcatga gcatggcact aatctttggt tgaactttac cagacacata
    24601 cagagtaaag aagagaaata gcaaaccaag cacgacttga ttgaataaat tagccaaacc
    24661 aactagacta agtcctacgg tctcccacat catcaatcta ggcaaggact gcttcccaaa
    24721 ataatcattg cccgtaaggc tactaatgat gattgctaac aaaacacaga cttgattgat
    24781 aaatagtgcc tctgtgtaag aaaaattcaa gagagaatgg ctcaaaaaga agatattata
    24841 aattccaccc aaagcgccac ccaaggcatt gacaagcaag acagcacaga gcataaaacc
    24901 aaagtttttc tgtccacttt taagaaaaac gagacgtaaa tttcgataaa ttgttaggaa
    24961 ctggtctttg atagaaagct tctcattttt tagtttttca ccatcagcag atgacattga
    25021 caggctcaat ttgctttttc ctaaaaagag gatagtggct gatactagga aaaagcaggc
    25081 attgattccc gcaacgagag aaaaattgtt gaccgataga gctaagagcc agactccgaa
    25141 agcttgacca ccaatagctg aaatataggt gatgaactgt gaaaaagaat aagcctccat
    25201 caaatcatct tcagctactt tttccttaat aagaggcata cgcaggccac ctgcaaaatc
    25261 actgatgata tcactaatga cattgatcaa acacaggcta gaaaaggcaa ataaactagc
    25321 ttgctgaaca actagggctg ccagaaaaaa taaaaccgcc tgaaacaaac cgctatagac
    25381 catccatttg accttggccc tcgtgtaatc tgcccgaatc cctgcaaaaa ctgtaaagag
    25441 agtcggaaga agcatgacaa tattcgccat agcaacagca aaagatgctt gtgacaaggt
    25501 cgatgcatag acgataaaga ccagattgaa aatcgaagca ccaaaagcat tgaagaagcg
    25561 tgataaagtc aaaattctat aagctggatt tctaaacaat agtttcatag ataatctccc
    25621 tccttgttct aagttctaca tcaagaatag ctttagtata gcacttatga atttgcgaaa
    25681 cgattctttt gaatatatgc aacaaataaa atgagcaaaa aaacgataga acttttgtaa
    25741 tgacctgaga gagggcaata gttctatcgc ttcaaatttt ttcttggttt gcagatattc
    25801 aacattcggt cgtatttcta tagtattcgg cagatttatt acagccaagc atctcaaaaa
    25861 tacggacagc atcctccatc tttttctggc cttccttgac tctaccttgc ttgctatcaa
    25921 ggagaccttc tgcccacaga taaacaattc ggaaataggt ctcattttcc ttgtagaaat
    25981 gctcttcgat aacacgttta aaataatagg cattggtaaa ttcttcacac tcaatactag
    26041 ctaaaaagcc attcaatagt atagtatgaa aaaggtttcg attgccagac atttccatta
    26101 gaaaatcaga tttacgtacc atttctcgta catatctagt aaaaagagaa acagataaaa
    26161 atggagaact gactgaaaat aaattgagtt catagattcc ccagatctcg gtagaaaaca
    26221 aataatcatg aaggactttt ccttcctctg ctgttaactc taccctttca tctatgctct
    26281 tcatataaga cttgataata atggcattta gaatatgttt ctgtttgttg tgagaatggg
    26341 catgcttttg atactccctg cgatataagt cctcaagagg tgctatattc tttggttcca
    26401 agacatctgt aatttctttt ctcaactcag aatctgtatc atactggaaa cctctcgcca
    26461 gaaagaggat ctcctccaca ctggcagata tattttccag agcaaataga aacttttcca
    26521 ccgaaagctc actctgacct gtttcaaaac gggacaacat agacggcgaa aattgtcctc
    26581 cggttgcttg tctcagtgag atatttcttg actctcgtaa ttgtctaaag acttttccaa
    26641 tctgctccat agacttcccc ttgattccgt attttcttca ttttatcata tttttcagaa
    26701 aattcatcaa aaacttgcca aattgtcaga attatgagaa aatagaggat atttatcacg
    26761 tggagggact gctatgagag acgatatcaa aatcaatgac cgtgctttgg ccttgcaaga
    26821 ccaaatcatc gaaaaactag agaaagtttt tgatacagat gtggaattgg atgtttacaa
    26881 tctaggtctg atttatgaaa tcaatctgga tgaaacgggg ctctgcaaga ttgtcatgac
    26941 cttcaccgat actgcctgtg attgcgccga aagcctgcct attgaaattg tggcaggtct
    27001 gaaacaaatc gagggtatca aagatatcaa ggttgaagtt acctggtcgc ctgcttggaa
    27061 aatcacacga atcagtcgct atggccgtat tgcccttgga ctaccacctc gttaagcagg
    27121 ccaatcactt ttaaagatga aaagggcaaa ctagaaaact agccgcaggt tgctcaaaac
    27181 actgttttga agttatggat agaactgacg aagtcagctc aaaacactgt tttaaggttg
    27241 tagatggaac tgacgaagtc agctcaaaac acagttttga ggttgtggat agaactgacg
    27301 aagtcagccc aaaacactgt tttgaggttg tggatagaac tgacgaagtc agtaaccata
    27361 cctacggcaa ggcgacgttg acgtgatttg aagagatttt cgagtatgag tttatttttt
    27421 acctgacttg tccatattcc agaagtctgt cacggctccg cgtgaagcag atgatacgat
    27481 gtgggcatat ttaccgagga caccacggct gtaaagtggt ggcaaggttg tttctgcctt
    27541 gcgtttttca agttcttctt cggatacggc catggaaatt tctttggtat cttggtcaac
    27601 cgtaacgata tcgccggtac ggagataggc aattggtcca ccatcctgag cttcaggagc
    27661 gatatgtcca acaaccagac cataagtacc accagagaaa cgtccgtccg tcaagagggc
    27721 caccttatct ccctgacctt taccaacaat cattgaagaa agtgacagca tctcaggcat
    27781 accaggacca cctttaggtc caacaaaacg aacaacgact acatcgccat caacgatttc
    27841 atctgtcaga acggcctgaa tcgcatcttc ttctgagtca aagaccttag ctggcccaac
    27901 gtgacgacgc actttaacac ctgatacctt ggcaactgca ccgtcaggag caaggttccc
    27961 gttcaagatg ataagcggac catccgcacg ttttggattt tcaagtggca tgataacttt
    28021 ttggcctgga gtcaagtctg caaagtcagc caaattttca gctacagtct taccagtaca
    28081 tgtgatgcga tctccgtgaa ggaaaccatt tgccaacaag tacttcataa ccgcagggac
    28141 accaccgact tcgtagaggt cttggaagac atactgacca gatggtttca agtcggccaa
    28201 gtgaggcaca cgttcttgaa tcgtattgaa gtcctcaagt gacaagtcaa catttgcggc
    28261 atgggcaatg gcgagcaagt gaagagtggc gtttgtagaa ccaccgagag ccatcgttac
    28321 agtgatagca tcttcaaagg cttcacgagt caagatatct gatggtttga gaccaagttc
    28381 caacatctta acaacagcac gtcctgctgc ttcgatatct tctttcttat cagctgattc
    28441 agctgggtga gaggatgacc ctggcaaact catccctaga acttcgatag cagttgccat
    28501 ggtattagca gtatacatac caccacaacc accagggcca gggcaggcat tacattcaag
    28561 acgtttcacg tcctcagctg tcatgtcacc gtggttccat tttccgatac cttcaaagac
    28621 agaaaccaag tcgatatctt taccatcaag atttcccggt gcaatagttc caccataggc
    28681 gaaaatagct gggatatcca tattagcaat agcaatcata gatccaggca tgttcttgtc
    28741 acagccaccg atagcgacga aggcatccac gttgtgacca ctcatagccg cctcgatgga
    28801 gtccgcgatg atgtcacgag atgttagaga gaaacgcata ccaggcgttc ccatagcgat
    28861 cccgtccgct acggtaatgg ttccaaactg tacaggccaa gcgcctgcag atttgacacc
    28921 ttctttagcc agtttcccga aatcatgcaa gtgaatgtta catggtgtat tttccgccca
    28981 agtcgaaatc actcccacaa tcgatgtttc aaagtcctta tctatcatac cagtcgcacg
    29041 aagcatagca cggttaggtg atttaaccat gctgtcatag atgctactgc ggtgacgttt
    29101 atctaattca gtcatcttat ccctcccatt tcagttttta ctattatagc acaatttaaa
    29161 ggcaatgaac agaataaaat tcttgaattt tcagaaaatt ctatacgcat atgaaatatt
    29221 taaaattaaa aacaacaaag cggattagtg cactttctga tgaccagaat atgcttttta
    29281 atccgctttc tttaaataac gtactgtaat ttttacagaa attctttcag ataagtgtat
    29341 ttaacatcta tcttgcatta taaatttcta gaaccttctc ttttatattc gattcactca
    29401 aaccatactc attaagaaga taatccattt tccctacttg accaaatctt tcttgaacac
    29461 ccatccgatg aatttttgtt attccatcat cagagaataa ttcacataaa gcactgccaa
    29521 ttccacctat ctgattgtgg ttttctacag taaatatagt ttttccactt aacattgttt
    29581 ttatctgttc tggtatcggt ttgattctaa ataaatctat cacacctact gaataaccta
    29641 atttagacag ttcatctgca actcgaatac ttggagcaac cattatacca gaagcaacga
    29701 ttacaagatc ttccccgtgt cttaactcaa tgtagccttt agaaaaatct tctccacctt
    29761 gatacacagg aactggagct tttctaattg ttcgaatata ttttagtcct tttaagtcta
    29821 atgtctggtt caatatttca cgaaattgga tatcatcagt tgcttcaaaa atgatcgatt
    29881 taggaattaa acgtaacaat ccaatttctt caaatggcat atgtgtccca ccattcattt
    29941 ctgcagttac tcctgcatct gatccaatca cagtggcatc caattgtgcg tatccaagag
    30001 aaataaataa ttgatcaaat actcttcgtg aagcaaaagg accaaatgta tgaagataag
    30061 gtctaaaccc ctgaatagac aagcctgctg caaggccgac catttctgct tccataatcc
    30121 caacattcac ataacggtct ccaaagtcct tttcaagatt atgagtagcc atcgaacttg
    30181 acaaatcggc ttctaagact actatatcag aataactttg attagcctct aaaaggaagt
    30241 ctctatatac atgccgtaat tctttcgtac ttctcatcat tctgtttcct ccaattcctg
    30301 acttaatctt tctacaactg aagttaacat ttgtttctcc tctacagtag ggcgaagatg
    30361 atgattggat ttcatttctt ccagctcttg aaccccttga cctttaatag tatctaatac
    30421 aatgcactta ggtgatgaat tatttgactg ttttaattgg acaatccctt cataaatttc
    30481 tctaatatct gaacccttga ccctaatgga ttcaaatcca aatgctgaaa atttttctac
    30541 gaaatcacct ggattacaaa tatcctttgt aaaaccatct aattgttttt tgttatcatc
    30601 aacaaataca attaagttgg ataactgttg atgagaagca aactgtatag cctcccaaca
    30661 ttgtccctca tttaactcac catctccaac aatagcataa gtataaaagg gactctttct
    30721 tattctctga ccatatgcaa gtccagttgc aacactaatt ccttgtccta aagagcccgt
    30781 tgtcatatct atgcctggcg ttagatttct atcaggatga gacggtaatt tggttccatt
    30841 tgtatttaaa gaatatagga attctttgtc aaagaaacca ttcaaataga gtgtactgta
    30901 tagagctggt cctccatgac cttttgataa tatgaaataa tctctatctc gtgctgcaaa
    30961 tatttctgga gtcattggca ttatttcacc ataaagcact gctaaaactt ctacgataga
    31021 cagacttcct ccgtaatgtc cgaagccaag atgattcaat gttctaagag tatttaatcg
    31081 gatgttagtc gcaaattttc ttaacccatc ttctctattt ttacttaaaa tcatccctta
    31141 ttcctccttt gcagatggct ttttaataaa ggatactcca aacataactg ctagaataag
    31201 aacaagacca atcacaatgc ctgcttgtga accaaattga tttaacattc ctaaaataat
    31261 tcctgataga ccaaaatctg catctgagaa agttgatcct tggaaaccaa gtcctcccaa
    31321 aactggcatt aaaaagactg gaagaaaact gattaaaata ccttgtaaaa atgctccaat
    31381 agtagctcca cgaacaccac cagatgcatt cccaatgaca cctgcagtcg ctccacagaa
    31441 gaaatgaggt acaacacctg gtaagataac aaccgttcct gaagcaatca taattaccat
    31501 acttactaaa ccaccaacaa aactagagat aaatccaatt agaactgcat taggtgcata
    31561 agtataaaca atcggacaat ccaaagcagg tttggaatta ggtacaagac gctctgaaat
    31621 acctttaaag gctggaacaa tttcgcccaa aataaggcga acacctgcta aaataacaaa
    31681 tacccctgct gcaaattgac ctgctaattg taaagcataa actagaccac ttgtaccact
    31741 actgatttct ttttctatat attctgaccc tgcaaagata gctacaataa tgtaaataac
    31801 tgccatagat aaagtgatac taacagtact atcacgtaaa aaagctaaac tctttggaaa
    31861 tttaatgtcc tctgttgatt ttgatttgtc accgataagg ctaccagtaa aaccactcaa
    31921 ccaatatccc aaagaactga aatgacctaa agccaccttg tcatttccag ttaattgaac
    31981 catatatttt tgcacaaatg ctggggaaat actcataata ataccgagtg ctaatcctcc
    32041 tagtaagata agaggcaagc tagtaaagcc agcaactgat aaaatgaccg caatcataca
    32101 cgccatatat agagtgtggt gccctgttaa aaaaatatat ttaaatcgag taaaacgagc
    32161 gattaagata ttgaacacca tgcctgcaaa cataatcagt gcagtagctg agccatatgt
    32221 tgttaaagct acagctacaa ttgcttcatt attcggcaca acgccagata aatgaaaagc
    32281 atgctcaaac atggtaccaa atggatttaa agaattttgt acaattcctg caccaccaga
    32341 tacaactaag aaaccaacaa aggtcttaat tccaccttta ataatatcag gtaatttctt
    32401 cttctgaaga actaatccta aaattgcaat taaagctact aaaatagctg gtgtactaac
    32461 aatatccaat atgaacttca tcatgacgct agcctcctat ataagtcctt tttcttcaca
    32521 aagtttagta attaattctc gtagttcatc catatcaata atactattta agatacgaac
    32581 atctccaaga tgactagctg aatcagctag atcacgacca acaatccaaa tatcagctgc
    32641 atttggatct gctccaccta aatcataatg ttcaacttct acatctgaaa cattcaaatc
    32701 actcaataca gattcaatat tcatctgtac cataaaactt gaacctaatc ctgaaccaca
    32761 agctgtacca atttttaaca ttatctaatc ctcctgttta attatcattt taatgtcatc
    32821 atagtttttt gatgatatta aagtttgaac atgattttta tctcttaaaa ttgttgttaa
    32881 atgtgacaaa gcctttaaat gactctcatt atcaatggct gcaatacaaa tcaacaatct
    32941 tacctcttgt tctggattat ccaataaata aatcggttct tccaaaacta acattgacat
    33001 tcctatttca ttcacacctt catctggccg agcgtgagga attgctactc ccttccctaa
    33061 attaataaaa ggcccaaact cttctacttt ttgaatcatt gcctcagggt agttctcagt
    33121 tatcttatct tgatccaaaa gcggtttagc tgctaaacga atcgcctcct tccatcctaa
    33181 tttttgcgaa ctaacctgat aggtttcttt ggtaataagt tgttctagca ctggtacaat
    33241 ttcctttcta tcattttttt gataaagata attctttaac gccaatctta attccaattc
    33301 ttgtgtaata attccatatc ttttgacaat attcaggatt tgttcaatct caaaatctcc
    33361 atactctaaa ttcggaaaat cttttaacac tagttctact agttgtattg cttgctcttc
    33421 agtcatcata accgaaacta gataatttgg cttttctgtc tccaccttta tggtagaaaa
    33481 aaccatatca tagtcactac tagctttcac ctgtaaatca tcaatctttg aggttcctat
    33541 aaactcaatt tgaggaaata atgctaatag attctctttt aacatcaatg aagaactaac
    33601 accattagga caaatgattg ctgctttata ccatttttga ggcaaagtat ctgctttctt
    33661 taaataacct ccgaaatgga taacaaaata tgctgtttca ctatcaggta tgggattgtc
    33721 aatagcgtcc atcaagggca tcaaagaatc tttgactaat tcaaataaat caggataatg
    33781 ttctttaaca tgcaatacat attcatttga actaggtagg ccgaacttta atctatagta
    33841 agccggtata aggtggcggc gaagattttc tctcaatcct tccctttgtt taaaatgtaa
    33901 caaagaaata tcttccattc tacttataat agcctctgtt aattgattaa agtaaaccgg
    33961 agcaacatct acttcacctt caaagcaact tgataataaa actgtgatat agcgataatc
    34021 atcctcagaa aacaccgtat ctataattcc caaatcaacc actgtatcca ataaaatagt
    34081 ggttatatct tgaataacag gagatactaa tgtctctgaa agacatactc tttcaacatc
    34141 cctttgatac ctacacagaa tgaatactaa accgaaaagg caaactttta attgattaac
    34201 aataggtact agctgtagct tctcataata atctttaact acctgattta tcaaatcatc
    34261 agttaatgaa tacccccaac tggataaaac ataatccaaa ccccaaatcc ctatggagga
    34321 ttccagcaac tcactaacca tttgaaaagc taaacggtgc ttattccact ctgaaccgtg
    34381 taaagtataa ccttttgctc tactgtaccc tagctccaaa tcattatcta acataatctt
    34441 tcttaatgat tgaatatcag ataaggttgt attcttactt actttcaaaa agtcttggta
    34501 atgattattc gatataaaat ctaatcggca aaaagtgtaa agatagatta aagctaagcg
    34561 agtcgacttt ggtaaaacca attcatccga cttaataata tctgtcaaag actgcttcgt
    34621 acgatttgat aaactatagc gaccttgctt tttatccagc actatcccct tattagctag
    34681 ataaggcact aaataatcta ttccttcttt gacttccttt ataggtaagc tcaccttaac
    34741 agataattca tataatgata gctcacaatg atccatcaaa gtcatcaaaa taactagtgc
    34801 tctataatca aacatttctc ttcctttcta actacaatta tagtgtaaaa gttataagaa
    34861 taaaagagta tttgagcaca atataatctc accttttaaa agaaattatt gggctgaaac
    34921 tttttagtga ttatttttca actttctatt gactttataa atcaaagtga tatcatttag
    34981 atatcaaata atgggaggtc attcttatga ctgaaaaact aatcaattca aaaccaaatg
    35041 gtgtattcgc attgattctc attgagttga cgctcgtact tggtgtcttt atatttataa
    35101 tgggggttgg ttctcaaaat atttttggta ttattatcgg acctttacta atcgtaattg
    35161 caggtctagc tcatgctggt ttaaaagttg tcaaacctca ggaagctctg gttctgacac
    35221 tctttggtaa ttatacaggt accatcaaag aacctggttt ttactttgtc aatcccttca
    35281 gcgtagcagt caaccctgca aaccacactc gacttggaca aagtggtgat gttagcacaa
    35341 aatttccttt tttaggagct aaatcatcaa atgacaatga tgtaaatctt gaaattagca
    35401 aaaaacacat ttccctcaaa gtcatgacct tgagcaattc tcgtcaaaaa atcaatgatt
    35461 gcttaggaaa ccctgtagaa atcggtatcg cggtaacttg gagagttgtc gataccgcta
    35521 aggcagtctt caacgttgat aactacaaag aatatctttc attgcaatgt gatagcgccc
    35581 tccgtaatat tgtccgtatc tacccttacg atgtatctcc taatgtggat actacgggtg
    35641 acgggcaagc agatgaaggt agtctccgtg gctctagcga aattgttgct aaccgtattc
    35701 gtgaggaaat tcaaagtcgc gtagaagatg ctggcttgga aatccttgaa gcacgtatca
    35761 cttacctagc ttatgctcca gaaattgctg ccgttatgct tcaacgccaa caatcatctg
    35821 ccattattga tgcacggaag atgattgtag atggtgctgt aggaatggtt gaaatggcac
    35881 tagaacggct caatgaaggg gaattggtag aacttgacga agaacgaaaa gctgccatgg
    35941 tttcaaatct ccttgtcgtt ctttgtggca atcatgatgc acaaccaatt gtcaacacag
    36001 gaagtcttta ctaaagatgg ctgaagctaa aaaaaagcag atcccccttc gactctcaac
    36061 aaagttatac gctgcactcg catcatgggc agaagacgac tttcgttcag tcaatgggca
    36121 aatcgaatat ctcctcacag agtgtgtcaa gcaacggaag aaagacggaa aatacgcatc
    36181 agaaaccatt gacgaaccat ttgagattga tatttaacat cttctcctgt ctgacaagtc
    36241 ggacaggaga attttttcat ctttttttgt caagtaactt tactttacaa acaaaatgtg
    36301 ttatcctagt atggttgatg aaaatcagta gattgaatcg aatataaata cctaaaggag
    36361 aaatcaaaat ggcagtacct gcacgtcgca cttcaaaagc gaagaaaaac aaacgtcgta
    36421 cacactacaa agtaacagct ccatctgtaa actttgacga aactactgga gattactcac
    36481 gttctcaccg tgtatcactt aaaggatact acaaaggacg taaaatcgct aaagctgcat
    36541 cagctgaata atagaaggga gataccatgc gcgtaaatat tacacttgaa cacaaagaat
    36601 ctggtgaacg cttgtacctt acttctaaaa acaaacgtaa cactccagac cgccttcaat
    36661 tgaagaaata ctcaccaaaa cttcgcaaac acgttgtgtt tacagaagtt aaataattga
    36721 gtaaaccaaa agcccttgaa accaacattt caaaggcttt tttctttttg ttttaggaaa
    36781 ataactgaat tttaactgat taaatattcc gtaatgatat atgaataata aaaaacggat
    36841 aacttctagt cttgattaaa gtttaaattt ggtatcagaa cagctccgta tgccccttca
    36901 gaaaacatac caacatataa tctaaacttc tctatcattg gtgtaataag tgcttgttga
    36961 aattcatcat cctgcgaaat atcttctggt aaatctgaag ctaagaccga atatctggca
    37021 tcaatgtcag caataactcg atactgacta tctgggtatg aaatttccat ctttatcaga
    37081 ataagttgat tctcttgtcc ttcctctctg tcaggaaaat ttaaattaat cgaagctctt
    37141 ccatcttctt caacttctcc agtgttatga gtattaaatt caaatttact aaatgttatt
    37201 cttcttatct caatattttt tgtcttcatt ttaacctcca atagaccatg aaactacttt
    37261 attatcttgg agtctattat tagtaatatt ctgctcttta taaggttgta ttttttcaga
    37321 ttgatttttt ataatgattg tttggtgaat atgttgctct ggtgcagaaa ccttttcagc
    37381 aatggtttga ctaagttttt tagtcatatc tttaaattgc tctgttagct gttcaacagc
    37441 attttgagtt tgtttgaata acccgtcatt aatcaattgt actatagttt gatttaagct
    37501 gactccttca atttcagagc gttctttaac atctctatgt aaggttttag gtaatcttag
    37561 cgttattttt ccactatact cttccagaga gttctcaaaa ggttctttaa tttttctccc
    37621 ccactcaagg ttggcctcaa tccagtctgc tttagctaat tcaatctcat cataaacttc
    37681 tcctaaagat tcaccataaa cgattaatcc tggtaactct ttaatagagg cagtaaacaa
    37741 taattcaccc tcgtcataaa ttttttcaat taaaatcgga tagttcaatc caagataata
    37801 ttctttatct ttcatcattt aaaccctcct ccaattctat cactttctca atcattttta
    37861 taactttctt catataaact ggctttatcg gcttatgtcg cggtattgga tagctttcct
    37921 ccaataaagc atgagaggtt attgaatgat tggttccttg cttccacata aaaccatatt
    37981 ttttacacag agattctaag cgttcagggg taacagattt ggggttattt tttatttttt
    38041 gcaactcttt ttccttgccc atgatgtacc tcatttacag cgacactata tatggtgtca
    38101 caataattat atcccaaaaa ttcgctaatt tcaaggattt cttttaattt taataaaata
    38161 tctgaatttc ataagataat taaaaaatta tttcagccaa atctatcata gcttgttcaa
    38221 tcttatcttt tcccttttgc ataacatgaa ggtagatttt ttctatctct ctactatctt
    38281 ctgaatgtcc tacaaattct cgaataacgt ttaggcttac attcttctct gccataactg
    38341 aaacaaagct atgtcgaaac atgtgaggaa ctatatgaat aggtctacca aaatctacta
    38401 agtcatcaat atctttataa ggttttccgc ttttcttatt atactttgcc aactggctag
    38461 cttcacctct taagaacatt gaaatttctg tatggtacat tgggctacct tgttgatttt
    38521 tgcctttaac gtagattcta gtaaatatat agcccatatc tttataagtt ggataaataa
    38581 taccattaag gaaagtgcaa gggcgcattt gattgaaagc cagggagtga aggcagtaaa
    38641 gtcaatgcct tttgccgtaa atccagcaaa ctcaagccgc taccagctga agataaagcc
    38701 tataaccatg cgctatccaa ggagagaagc aaggttgaga acatctttgc caaagtaaaa
    38761 acgtttaaaa tatcttcaac aacctatcga aatcatcgta aacgcttcgg attacgaatg
    38821 aatttgattg ctggtattat caatcatgaa ctaggattct agttttgcag gaagtctatt
    38881 gaaatactaa tcctacacag actgattcca attgtttttt agatttcaat tttaccattc
    38941 ttcatagtca aaaccatcat aatctggata ttgttctagc gacgttccaa ccgaacgtac
    39001 gagataagct tcttcgtcct ctgtctagat ttctctcagc acttggcatt caaaacgcca
    39061 ttcatcaccg aagtcgaaaa taaacttaaa tttttgtttg acacttaggc tatccagata
    39121 gacattttct gtgtaacgtt cttcaacatc gtcactaaca aagctaagaa agtaagaatc
    39181 tgcatgactc cactcaacat tatccatgaa aaatgcgtga gcatgatcaa ttgcaaaatc
    39241 aaaactccat aaaatcacat ctgctagttc cgctaacgtt tttgtttttg gaatctatat
    39301 atgtcggtag caaccttttt taaatttgac ggaaatgatc caagcttcta cagatgctgg
    39361 cttttcagct tctatttctt gttttactaa ttttaagtgt agcataatac ctccaattgc
    39421 tcatcgatag aattgctctt aggaaacatt cactttctgc tattttatca taagtttgtc
    39481 taactgtagc atttgaaacc agataattct tctgtttcac gcgaaacacc ctgcgccaag
    39541 caaggtattc ttgtttttat actcaatgaa aatcaaagag caaactagga agctagctgc
    39601 aggctgctca aaacactgtt ttgaggttgt agatggaagc tgacgtggtt tgaagagatt
    39661 ttcgaagagt atgaagagta ttaagtcgta taaatcgtcg acgctgtcgc aatggtatgc
    39721 cactggttag ctgtagttgc tgcgaagtcc ttgtctgcgt agaagtcagt aaatggtagg
    39781 atttcaactt ccagctcgtc gatgcggtca agctggccag ccagataaac ctcgatacgg
    39841 ctttctgctc gtttgatgcg ttgcaagagt ccgcccatac ggatgtcaac tgtatccaaa
    39901 ccaaagacct tgttttcttt cagccattgg tgactaaaga gggcatggaa gtcttcaatt
    39961 tggcttctaa gttctggtaa ttcttgtctg gcgatttgtt gtaaactttc tttatcatcc
    40021 gcttggtagg cctgacgaat gcgtcgtccc acatctactt tgctacttaa aatagcattc
    40081 aactgggcct gagtttcaaa gagataagca tagtttccag ctttttcttt aatgtcagca
    40141 atagttcccg ccgcctgagc gaagtgtggc ttgtcctgtt caggtgtcat gtgtcggtca
    40201 agtatcggac agagaacatc ctgataaaag acatagcggt tgggattgat gccactgaga
    40261 ttacctggta ggtctggtaa gaggttggca aggtcaatct gcataaaatc ctcaaccgtt
    40321 agaccagtat tggtcttgaa atgcgcagac aaactatcta ggtcattgcg atagctgagt
    40381 tctgcccaga tttgcaagct tggtaggata gagaactggg cagtttcacc accattgtct
    40441 ccccaacccg ttacgatgac ttctttaatc tgattggcac ggcaggcttt attagcctcg
    40501 atagctacta gacggctaaa atggttgtga ggtgtaaagc caatccactt ccaagctccc
    40561 cctgcaaatg caaggtcatg gctaatcttg tgatgattgc ggaaattacg gttgtatttt
    40621 tcctcgctat cctgataata atcccagtaa accagagtca cacggtcttt gagacggtct
    40681 aggtagacac gagtttcctc tggaatttcc acatcacggt cgtactggcc atccgctgac
    40741 atgagtttga agaacatatc actccacatc tggcagtgga aaccatattt gtcagcaata
    40801 tccagcacgc gctccaagtg ttggcacatg aggagactac gattcacaac accgtccaga
    40861 atcaggtagc gtcccaaacc aaccaagtgg gcttcatcca tcccgatatt gaccttgcga
    40921 gtcttcagtt tagacaacgt ggcaaacatg ctatcaatca ggtcataaac cttttcttcg
    40981 ccaatgagaa gaatgtcctc tacatcacgg agctcttgca cttccttgac accccatttg
    41041 acgaaggctg acaaatgggg caaggtctgg atgcaaggca caaaggtcat gtcaaactgt
    41101 tgggcatagg cttcgatttc ctgcaactcc tcaactgaat aagctccacg gaaatagcca
    41161 aagtaaggtt gcccttcaat ctggtaagtg tcttccatgt aaagctcaaa ggttgagtag
    41221 cccatgagag ccaatatctc aatcatctgc ttggcagaag cgacatttag caccgcattt
    41281 cgagaacagt caaccatgta agccaaatct tcgtaagctg cttgttcctc aatctctact
    41341 ttatcagctt ctgctagaac tgttaccaac aaggacaagg cacgataaag ttggtgaggt
    41401 ttgcggtagg tcaattgata gtgaccatcc tcacccttga tagagataga ggcttggtca
    41461 gactgagcga ctgacacctc aacatctggc agagaaatgt gaccttttaa aacctcaata
    41521 gcttgcgttt gtttgggact aagtcctgta aatcttacca ttgcttttcc tcctgtagcc
    41581 agttgacaag ggcaccgtag agattggcat ctgcatgata ggtgcaggcc tggataactg
    41641 gtgcgaccgt gtattcttcg taggtatcga caaagttatc aacagccttc ttaatacctt
    41701 ggataaaatc tggattttga ctgatagagc cacccagact gatgacatct ggatcgatca
    41761 gatactggat attgagcaag ccttgcgcca gattgcggtt catgcgctca atggcttctt
    41821 gacaaagagc attaccagct gcggcctctt ggtaaatctt gcgaccgtcc caatcagtat
    41881 gaccagattt ttcaatcaca tatcgtacca tattcccagt tgacgctagt tgcgaccagt
    41941 tattaagttt ttcagcaggg gcaagggttg tcatgtagcc aaattctcca cccagaccgt
    42001 ggcgacctcg atgaagtcta ccattgatag tcatggctcc accaattcct gtcccaatca
    42061 cgacacaggc tgcattttca agctctggat gagctagtag ttcactgagt ccaacgcagt
    42121 tggcatcatt ttctaaatgg acaggtagct gataagagct aagcgcctca tgccaagaaa
    42181 agccatggat gtagggcacc gcactgaagc catcaatcac acctgtctct tgattgactg
    42241 cacctggaac actcatagca atcccactgt aatcctgttc tgacaagcgt tgatctagcc
    42301 acgctagtaa atcctccaag ttttcaggcg ttgaaatact tgtcttatcc agtattttcc
    42361 catcaggagt cagactggca aacttaatcc cagtccctcc gatatcaatc gttgcaatgg
    42421 tcattgtttt taccataaaa aggggcgaat cagcagttag ttcttacttt ttcgcccctc
    42481 ctttcttttg atgtttactt tttgaaatta aatttcttct tttttgatga attctgtacg
    42541 aatctcttgt ggagccaata gtcctgaatg aactggatat ggtcgctcaa gtaagtcaag
    42601 aatggtttgt tgatgttctg atatgcgcac attttcttga ctcatattat agtaacggag
    42661 gacatagcct tcttcatttt ccgccacttt aaaggctgtt ggacaaactt gcggtatgct
    42721 gagaacagaa tggctcaaga ggctaccagt cgcaaccacg cttccttcct gtctagcaag
    42781 ctgaaggctg gtaaacggtg tctgcaaggc tttggcacga cgataggctg agaagcgttc
    42841 ttgggcttgg tggcattcaa gtgcaaactc gacttcaaac tcacgcaagc attgtgcttc
    42901 tggcgttggg aagtagcccc agtcacctag ctcacctgat gcacgcaaaa tggtcacggc
    42961 aatggtgtta tccccaagga tttcgtattc attcaatccc ttattggata cagtcactcc
    43021 tttttcatcg tcatacagac tgacaaaagc ttgttgatgt tgaggatttt cccatgaagc
    43081 tcctggtttg tttggtcgtg tcaccacctc atagatgctt tcagaatcat tgcttggacg
    43141 cgtgttatga gtcttgacca agagacggat acggtgatcc ttggcagtgt tagtaaagcg
    43201 agtcttgaag cggatttgtg gattgtcaac aaagacagta aactcagttt ccagaggaat
    43261 gtttgtcaat tcttctgacc gtccagcctc acgcttcata aactcgatga tacctttttg
    43321 ctcttcttct agcttttcat ctgcactgac aggcacggtc aattcatgtt tgagcaaaat
    43381 cttagcatag cgagctgtgt tttccaagac ctcgtagccc ttaagctctg caaagattgg
    43441 ctctgttcct tttggttgga aatagatata ctcgtttccg atgtccccac ggtcttcaaa
    43501 gcggataaag tcttcataag cttcgtgagt tgtcttgtca taaactgtga tattgtcatc
    43561 tacactcacc gttacgaatg gtgtatcaat cactccgttt tggtaaatac cctcacggtg
    43621 ttcttgtttt ccttccagca attggaaggt tgtccaagaa agcggtgcta ggtgaactgg
    43681 aatggtcacg cgcacttgtc gagcaatacg agcttggcgg aacttatctt ttggtaaatc
    43741 gtactcaaaa ttagctccga ggtcttcgat tgtagcctct acaggacgac catccaagtc
    43801 ctccacacgg tagcttggca agataagagc agccatcttt ttgtagcctt ctgttgggtg
    43861 caattccttg aaatcacaag tcgccacatc aatcactgtg ctgacagtat cgaccttatc
    43921 atgcaagcct gtgttaatga cagtaaagag atagtcactt tgagccttat ccgtagcaat
    43981 tttacccttc cactcgttga gcaagttact tttaacaaag tttcctactt ggttgacctt
    44041 ggcaaaacgc gtttccatct cgcggtgaac ttcgtccacg ctacagccac agatactatc
    44101 atgtggcgca ttctgcaaaa gtgttttcca agcataggtc aactggtcct tgtggttgtg
    44161 tccaccagtg ataatagtca aggattctac cacttgctct aggaggttgc tattttcttg
    44221 gaaggcttgt tttaggtaaa tgcgagatga agaagtgttg gcaagtgtgt accagccatc
    44281 tgtttcctga ctggtcaact cgcctgtaac agttgataag tgttcaggaa gcgcaccttc
    44341 tacagcttga acatattcat caaaagaatt atgaacaaag attacatccg ggaagagttc
    44401 atttgccaca cgaatggctt cgctcagatt tttctgtaca ggctggtggt cacagccgtt
    44461 catcatcaac catcggttgg tcgaagcgta ggcacgcaca tctgacaatt tttgtttcca
    44521 gaaggtcaag gcctcatctt tgtcaactgg aatttcattc ccgttactgt accagttggc
    44581 aaagagaata cctaaaacac gactaccatc cacaccctgc cagtacattt ttgaaaactg
    44641 ggatgtaaac tgctcatctt caaggacttg gttgtcaaat ccaatctgct tcacaccacg
    44701 accaaaggcg gtcacgtgaa tgcctgattt ttgaagaatt tgaggcgctt gtcccatatt
    44761 tccaaaggta tctggaaagt agccaatctg agttgattta ccccatttgg cagcttcttg
    44821 ttgaccaatc aaggtattgc ggacattggc ttcacttgaa atcaaataat catcctgcaa
    44881 gatgtaaaag ggaccaattt taagcttgcc ctcgtcaatg tagcgttgga ccttgtcgcg
    44941 attttcaggg cgaatttgta agtagtcgtc aaggacaata gtttgtccat ccaagtggaa
    45001 actcttgaac tcagggtcat tttcaaagag atcaaagaga ttgtcaaaca attccaccaa
    45061 ctgcatacga tggctttcaa aaggcaagta ccactcacgg tcccagtgac tatgtgagat
    45121 aatatgtaca acaacatttt ccatgaagta aaacctcatt ctaaatttaa attttaacgt
    45181 tttaaatgta aacttgtgat tctgataaga atcggttgag ctaatactca acgaaaatca
    45241 aagtgcaaac taggaagcta gccgcaggtt gctcaaagca ctgctttgag gttgtagata
    45301 aagctgacgt tgtttgagag attttcgaag agtattagcg aatatccaag taatccaaga
    45361 ccaactcaca gaacatcatg ttagcccagg agaaccattc acgagagtag agggtcggat
    45421 catctacgtg gaagctttcg tgcatgacac ctgtaccacc atcgcaggca accagctgat
    45481 ccagcaagaa ttttttctct gccttatctc ttgttgtcaa tccttggata gaaagggcga
    45541 ttggccagat atagcgatag aaggtatgag aacttccgag accgctagcg tattctcctt
    45601 ggtagaagta tggattttca gagctcaaaa tggtacgacg agtagcttga tacacttcat
    45661 catcgaccga acagtagccc agatagggcg cagctagtag acttggtaca tttggatcat
    45721 ccatgatgct ggcatttcct aggccatcca cttcaaaggc ataaatcttt tcacccttac
    45781 tgttggtggt gtaagcatag ttttcaattc cttcttggat ctcatcctga agacgcttgg
    45841 catcagcaat aacactctgg ctatcagcta ggtttaatgc tgcgaagatt tcttgcacat
    45901 aacccaagac tactacagca aacatatttg acggaatcaa gtaactatac tggcaacagt
    45961 catcactcgg acgaaaagct gaccaagtca tacctgtcac tgcaaagtca ggtccaaagc
    46021 catcatttac taaggtgccg tatctcggac aaaacgataa ggagagttct tgtggtcttg
    46081 ttcaactgtc catagatgga gaatttcctt agtcgctgcg acaaaagttt catcaaactg
    46141 actagtctcg ccagtctctt tccagaggag ataagccaac tgcaagggat agcaaagtga
    46201 atccacctca tacttgcgct cccagatcca gccgttaagg tctgtgtggt cagtctcgtg
    46261 gtgcccttta cagttctcct caatgttgaa ggagttagca tagggatcct tgagtaccaa
    46321 ggtcatctga cgtttgacca aacctgcaat ggtctgacgc aggagggcat ctcttttagc
    46381 tacatgaagg tagggtctga gttaggctgt cgaatctcga agccacatgg caggaatatc
    46441 cccagtcaag acaaaagttg aaccatcttc taagatttca accgtattgt ccaaggtatc
    46501 ggtgtagcaa cgctcgaaaa catccaccca ctctggatgg tccttagccc gctctgctac
    46561 ttcatctagc cattctctaa caatttcttt cgaataaatc atcgtgcaat ttcctctttc
    46621 aaacaagttt cattttcagt atatagcttt tgagacagaa aatacataca caaatgatag
    46681 tcatttttct acaaaatagt tatctttaaa actccttttc taaaggtcct ctttttctga
    46741 tataatgtag aaaaacagct aaaggaaaga ctatgaaacc actacttgaa atcatcgata
    46801 cccgctttgg aactaccaac aagcatgcct tttctcgggg aaataccctg ccatacacag
    46861 gcgtgccttt tgggatgaat tactttgtgc cccagaccag tgaccaggat ggatcttggt
    46921 tttttgatcc gcatctgcct atctttcagg ggattcgctt aactcaccag cccagtcctt
    46981 ggattgggga ctactcttgg ctccttctga cacctgtcac aggtcagctt gggggagaca
    47041 gtctctttca ccgccaatct tcctatgata gggataaggc ctctttccaa cctcactatt
    47101 tgaagctctt ttctctgcgt tatcagattg aaacccagct cacaccgact tgctacggtg
    47161 cttctattcg tttgaagcaa aagcaaggca aagccctctc cctctatctt cacgcagcag
    47221 ataaactgac agtagatcaa gtagataagc ggactcttgc cctgcgacaa gaaggtaaaa
    47281 ctgaaactaa caaaaattcg ctaacgatgt tcactgccct gcaaatgaac acggatattc
    47341 ttgctatcag ccaagaagct ggagactggc gaattgactt agcaagtagt caaaccgaga
    47401 tgcaactagc cacttctttc atctctcctt ctcaagctct aatcaatcta cctcaagaag
    47461 attttgatag ctgtaaaaca aatgcccaag cggattggga aaatctcctc catcgttttg
    47521 acattataga gacaggagag gctgaccgaa ccttctttga ccactgcctc tacagactct
    47581 tcctcttccc acagactttt tatgaggttg atgagtcagg gcaagccatc cacatggatc
    47641 tggctactgg tactgtcaag cctggtgtcc tctttagcaa caatggtttc tggaatacct
    47701 tccgcaccac cttccccctc tttgccctca tcataccgga gcactatcaa cgctttttag
    47761 aaggtttcct caatagctac cgcgatactg gtttccttcc aaaatggctg gctccagatg
    47821 aacggggtat gatgccaggt acacttttag acggtattat cgcagatagc gcctgcaagg
    47881 acatgacccc tgacctagaa ggagaactct tccaagccat gctcgaaaca gccagcaaag
    47941 ccgaccctct cggaatcaat ggccgccacg gactagccca ataccaagaa ctaggttacc
    48001 tctctaccga ccaccacgaa agtgttagcc atactctaga ctatgcctat agtgactttt
    48061 gtatcgccag ctgtgccaaa aaactagaga acatagaaat cgctgaaacc tacaaggctg
    48121 cttcacaaaa ttaccgccag ctatttgacg ctgagacagg ttacatgcga gcacgagaca
    48181 atcaaggaaa ctttcaccct gacttctctc cttatagttg ggggcgagac tacgctgaat
    48241 gctctgccat tcaagctact ttaggcgttc tccacgacat ccctggctta atccaactta
    48301 tgggtggaaa agaaaccttt agcaactatc ttttgaaaac ctgtcaagat gctcccctct
    48361 ttgaaacaac aggctatggt tacgaaattc acgaaatgag cgagatggct actgctcctt
    48421 ttggacaaat agccatttcc aaccagccta gtttccacat tccttatcta ttccgctaca
    48481 gcgattaccc tgactacact gcccttctta tcaagacgct ccgtcagaaa gcttttcacc
    48541 caagttggga agcctatcct ggagatgaag acaatggtag tctctctgct tggtacatct
    48601 ggtcagctct cggattttat ctaacctgtc caggaaaacc aagctatgac ctcggaatcc
    48661 ctctctttga ccatctacga gtctacctag ctaaagaaga taaatggctg gatatccata
    48721 ctaaacaaaa ccacaaccat tttaactttg tcaaagaatg ccgactggac aaaacactcg
    48781 tatcaactat tcaacaccaa gacctcttaa aagctgaaca actaactttc accctcagct
    48841 ggttaccaag tcagccgtca acttcctgaa atgcaaaaat ctcctagcag gctttcctgc
    48901 taggagattt tcttatgaga ggtatttgtt taatactcaa tgaaaatcaa agagcaaact
    48961 aggaagctag ccgtagactg tacttgagta cggcaaggcg aagctaacgc ggtttgaaga
    49021 gattttcgaa gagtttaagc tttaaaaatc ggatttatta ttcgataatt atcaaacaat
    49081 ctaccaatta agcttcttcg tcttctttac gacgacggcc tgcaagacca aggtaaggca
    49141 cttgcggctg ctactaccat agctacagta gaatctgctg tacctgtatt tggcaactct
    49201 ttagcgactg tacgcgcgtt tgctgctgct tggttggcat ttgctgcttg agcagtagct
    49261 ggagctacag ctggtgtttg agcagcttgg tccttagctg ggcttgtatg gtcagttgct
    49321 ggagaaactt tagccatgaa gtcttcgata cgtttaacca ttgcatccac ttcatcttgg
    49381 cttgctttcg gatctgcaaa tactttctta gcgtctgcca ataagtcagt cgcttctttt
    49441 gcagtttctg catcaagctt agctgattct tggataatca attcatctaa ttgatggata
    49501 gcaccttaaa cacaagaaag gtacagagat gcaaaaccat tatactacaa aaggcaaaca
    49561 tttgacaatc gatagccgtc gcttaatcga aagatggaaa aaagaaatga attatgaaga
    49621 tattttatga agatatttta tctcgtttca actaaaatat gagcttgatc aatcagctgt
    49681 ccaccaacag tcaggttcag ataaaaatcc aagatcttgt cggcagcaaa atacagagtt
    49741 ggtatgctca agtctttttt gctttcccct gcttggaatt gaaggacttg aatctcgtcc
    49801 tgataggcga caccatggac acctgtcccc ggttgaatcg aaatcttagc ctctaaagag
    49861 gagctacttt cactacgttc aatcctaaaa tgaagagtct ctccctttgt aacagctagg
    49921 cttttttctg caaatgctag ttcctgaaca acttcttttt ttgataatcc aggagtttta
    49981 taaagggaaa tcttggtcaa tacaggaata gattgtgcct ctgtaatcat cacgcgcacc
    50041 ttctgtgcct ctactagcgg acctcgcaag aggcgcttat gaccaactgt gaagcccctg
    50101 ccgaattctt gccagacgtc atccacctct acttgcacat aaaaagtagc gattcgttgc
    50161 cctagcttca aatcttctct taactcaatt acatcaaaag ttttaggaga acctaagtcg
    50221 agttctaact ggattggcaa gcctacatcg cttgccccag agctagtttt aaggccatct
    50281 gtcagatgat aacaagcaaa gtctacggaa agagctgaac cagatatctc agctcccaga
    50341 gccaaatctt ttttatagag ctcattacga taggccgcaa attcataaag gcgttcaaca
    50401 tcctttgcat caaagagccc atctttattc ggcggaatat taagcaggag tggagttcct
    50461 ctcccaaccg agtgaaagta gatttctacc aattcctcga gagacttagg atactgatcc
    50521 tcatggtaga accagcccgg ccggatagag acatctgcct caccaattga aaaaatcgta
    50581 cccgaaggat ctccgtgctg aagatagtcc agctctgctt ctgttcctag tttgtcagga
    50641 ttcacctttt gccatagggg atcacctgca tagcctcgtt cattaccaat ccagcgaatg
    50701 ctagtgcctt ctgttgaaaa aatcaagcaa tcgccctgca ggtcacgaat ggtttcaaac
    50761 catgtctcaa attcataatt gaccttttgc gcgccctctc ctctggcacc atccatccaa
    50821 acctcagcaa atttccctcc atttccatag gcaggatttg ataagatttc cttcagctga
    50881 gccagataat aggcattgta gtccgcttct cggtccacat gatagagggg actatgggca
    50941 tcccacggtg acaggtagac ccccatatcc atatcaaact ctgtggcagc ttgagatact
    51001 tcaagaagca agtcgccctt tcctcttctc caaggactga ccttaatcga ataatctgtg
    51061 tgagctgtcg gataaaggac aaagccatcg tggtgcttga ccaccaaaat caactttttg
    51121 aagcccgttt ccttgagcac acgaacccac tcacgtgcgt ctaactgtgt cgggttaaag
    51181 cgttcaggat cctcctgacc tgttccccat tcctgattat aaaaagtatt aggtccaaaa
    51241 tggataaagg ctactagttc atcctctaaa tacgctaact ggacctgact aggcaagggg
    51301 ctatgcggtt ttatttctct taccatacta cttcctatct acattttctt aactttttgg
    51361 catgtacttg caattctgtt aacgctagtg gatttaccaa gttttcaaat cgaagacgaa
    51421 gggcataggt ttccaccttg tcaaattcaa aacgaagctc ttcatccttg tcacctgaca
    51481 cttttcggat agttgatacc ggtcgccaat tctcctcttg tttgagagca gaatccttat
    51541 ccaaatggtt tggagtccga ggcaaagtag gctcattccc tatgtaataa tcaataaagc
    51601 taggctccac cgccacgtat tcttgattct caacataata caaggtcagg ttatccacaa
    51661 atcgcggttt taaaatccct acatttccaa aaagaatacc cacgctggct tgctctgact
    51721 tggtaatcca agtattggct gtcgatttct tccgagaaat gaccttgtca ttgaggtaag
    51781 aggcagggtg attcgattct gagtgagaag caaagaccag aggtaggttg gagcctgtcc
    51841 actgattgga aataacttcc ccatctacac tagcatctgt cacatgaatg gtgactgttg
    51901 ctggtaactt acagcccact acttgtcctg tgaacacaca ttctcctacc tgagcataga
    51961 cttggggttc gagttcatcc taagttacct tggccgtatc tcgtctgcca tctgataaga
    52021 ctagcttaac tcggtctggt aaatgtgggg cttccttgac aagcgtccaa accctctcag
    52081 actcaatagc acaaatccct tgaacacaaa cctgagcaga agcctctaaa tccagaccct
    52141 ctagctgacc agataccgta aactcatgaa atcttgccaa atcttcttca ggaatctcct
    52201 cccagacaac cttgactcgt tttgcaccgc ctgactcata gtctaccaag actgaaaatg
    52261 gcaactgtgg ataagttccc ttatctgtat acaagcgaag tggtcttaca aaaactgcct
    52321 gccctagtga ggtattttct gcaatctgca aatgagtttg ataggtcttc ccttgataaa
    52381 tggcatgaat agccaagtcg cctgcagaca agcaatgaag tactccctgc ttgataatgg
    52441 cgtgggcact accactcgtc tcccaaaaca cttcactatt ccctaccttg ttcacaggat
    52501 tatccacagt ttgtggataa agtccaatag ctggggaagc tccttcttgc aaacctgcct
    52561 gatcgtccac tcgaatctcc aacaagcgct gatttttcac tggctggcaa tcaaaagcct
    52621 ctcccactaa gagatcaaaa cttgctggct ctagccctct ggcactagct tttactctta
    52681 cttgacctgc ctgctccaag ctctgagcct gataacgttc acgactggcc tgcctgccgt
    52741 tgtccacacc cacaatacga gctggtcctt caattttgaa atgaagctga ttggaagcac
    52801 tcggcaccca atttccatcc ttgtccaata catcaaaata gagatagagg aggtcttgcc
    52861 catctggctc tagttgtgtt ctctcggcat gtaacccaat tttagcaggc ttacccgcag
    52921 tcaccaccct atcttctgcc acaatctgac cttgacggtc ataggccaca acacgcaatt
    52981 ctcccggttg ataagccaaa cgccattcga gatagagttg gtcagaacct tctccctctt
    53041 gatattttct gccatctgaa gtccatttct cttgaaaagt cttcctgcct tgagattttc
    53101 cattgagaaa tagctctact ggaccagcat ttgaatacac tcgaaccggg atatccccat
    53161 acttatccac agcttgttga taactcttgt ggatttccca attccagtgg ggcaggatat
    53221 gaaccacggg atgctgatct aggtccaacc actgactttg atagagataa taatcatttt
    53281 taggaatcct cgccgtgtcc acaatcccaa aataagaact cttgacaggc gtgtcatttt
    53341 gattgtgcca aggggtcggc tcaccgatat agtccactcc tgtccagata aactgacctg
    53401 cgtagtctag cctatttcta tctgctatca aagaagccgt cgctgtcttc ccccaaggaa
    53461 ctcgatcatt gccatagtct gactgttcaa aattccgcac gcgacgatta tccccaacct
    53521 attccttatc tgggcgaaaa tagctatcac acgttcgggt agccgatgag gtttcagacc
    53581 cgtaaagtcg ccacttggga tgtcttttgc gaatcccgtc aatattatct tccgagtaat
    53641 tcaaccccac cacatccagc aaatcagcaa tcttttcatg acctccagaa ccatctccaa
    53701 agcgaaattg atccattccc atggtcacaa aacggctatc atcaacctcc ttaacccttt
    53761 ctagcaagcg tttgacagtt ttcaatgaat gaacatcgct atttgcttcg ctgacttcat
    53821 ttcccaaaga ccacataaaa atcgctggat tgttcttgcc acgctcaatc atagtgcgca
    53881 aatcgtaatc cgaccagaaa tcgcctgctt tcgcttctgg atgagtcgct tcttcctcaa
    53941 aaaagcgacc atagtcatat tctttcttgc ctccatacca gatatcaaag gcttcttctt
    54001 ggatgagtag acccattttg gcaaccacat ccagcaaaat actactggct ggattatgcg
    54061 tgattcgaat cgcattgacg cccatttcct tcatctggcg caagcgtctc tcagcagctg
    54121 acctgttttc catagttccc aacgctccgt agtcatggcg caaacaaacc ccatgaatct
    54181 tcaaccagcg accatttaga aagaagccct tatctgcttg ccaatccata tagcggtaac
    54241 caaaattctc ctcttcttca tcagctaaaa tgccattttt gtaaaggcga gtcttcaatt
    54301 ggtaaaggtg aggggaatca atatcccaaa gcaaaggttg gaaaattgat atggcttgtt
    54361 ggaaatgatg tttgtcccca gcttcaatca ctacagagtc tgtcgcctgc cagtctgaaa
    54421 cctgttgtcc atcataccag atactctgtt ctaaatacac cgacacagac tgaggcccat
    54481 catttgaaac cttgctttca agctgggttt ccacccatcc atctctttgt tcctttagct
    54541 tgggactttc tatcttaatc ccatacaaat ccagatgaac tgcatctgtc atcaacaatt
    54601 ttacttctcg gtaaataccg ctaccagagt accaacgact gctaggttgc tgattttcca
    54661 caaaaaccgc aagctggttg gccgtcccat catttcttag ataaggcgtg ataacatatg
    54721 aaaaaggtat atagccattg ggataatagc ccagcacttg cccgttgata tagacttggg
    54781 cattcatgta aactccatca aacaacaaac gcaccgatac aagactggca tcttcttcca
    54841 agtaaaactg cgtccggtac caggcctgac ccccatttag ctgaccaccc tcattttgcg
    54901 ctggcgaata ctggtcaaaa tcattgtaaa tactccagtc atgtggtact tgaatcgact
    54961 gccaattttc cctctgaaaa tccggcgcca aggcctcttc tttccctacc tcttgactaa
    55021 aaaaccagtg atttcgtaaa acttcttctc ttctcataca agcattcctc tttaaacgac
    55081 tcgatttact tgactatagc acaaaacaaa agcgctttca agatttcctc tatcactccc
    55141 taaatactca gaaaagattc tataatttgt ggaaaagtct gaaaatcact ccatattcaa
    55201 gcaaactatc attttcaaga aataaggtca aaccttacaa gagagcaaaa aacacctctc
    55261 tgaatgttca ttccagagag atgttccttt tgtcttaact attgtaaatc gactgtctaa
    55321 agtcatctga atctttgaga taagctttat aaatcgcttt tttcagtttt tgaactggag
    55381 tttcgataaa ctcaaacttt tgagccgtgg tattgcctgc ttttatctgg gctagttcag
    55441 ctaaaacagc tttctgcatc aattctttta acttctgact tgtcagactt atttgctgac
    55501 cttcatattg gattgtcaaa ggtttcaatt gattgagcct atctactctt tccttgaact
    55561 gtgctttttt aaactcagca tagctcttac cattcaaaat tttattgaaa atgtaagtat
    55621 cagatagagg cttgttctca gactctgcta cttgcttgta ttgatttgat acataaggta
    55681 caaatccttc ataatagccc aaagcagcca tcaattcaaa tgcttgtttt ctaaaggtga
    55741 tgtccccact cataccagag tcattttgac taacaccata aatggtatca aacatatcca
    55801 ctaaataata tccattagct tttacatcac ctgttgcata aaatccattt atgatataac
    55861 gattaactaa aatattatta tcaatcaagc tattgatatc cgttagtttt tccgcttctg
    55921 ccaatgtgat ttccgagatt ttttcactct tgtgcgtagc tttaaccgct gaatttgtat
    55981 atgttactgt cgctctaggt cccttcgacg caatcggtgt tatttttttg aaatatttag
    56041 ttttatcttc agctgtaagt tgttttgttg cttccgcttc taaataatct aaactatata
    56101 acacatcaaa acttccatgc atataagatt tcaagtctgc atctgttttg aatctatctg
    56161 gtgttttgtt gtagaagcca tttttcttac tttcatcgta aacgaagttt aagttaaaat
    56221 atgtatcttt ttctggtgtg taagaatttt caaagatacc tcgagcataa aactccgcag
    56281 ctgtaccatc tcgacgacca tgattattaa acagcactgt tctgtctaat aaatgcgtca
    56341 tttcgtgaga gtaagtcgct gagcctctat catccagaac tctatctatg aagtaacgga
    56401 cacctactcc attggcttct gcacctacat tttgcgatgg tgaatacagg cctagaggtg
    56461 tcataaagtc tttaacccct ttatctgctg ttggtcctga ttctttagac catgttgtcc
    56521 ctattccagc agacgtatcc gccgtgtatt ttttcatcgt gtctacaatc actctatttg
    56581 taactaattt agaacgattt tcttcttttg taattctgta taaagtatca acgtatgcag
    56641 cctgtcttgt cgcagtcaat tctatcaatg ctttaacttt ttctaattct tctttatact
    56701 taactggatt tgttttctct aaagaagtat ccatatacgt tccgatattt ccgtaggtca
    56761 ccgtcgctat gttagttata gcatacacgc ttggttcttt aatatttacc aaacctaata
    56821 atatagctac attttgttgt cttctacttt caatttgaag attttcagct ccatatttct
    56881 caggaggtgt agttaatttt gtatataatt ctactttttc gtcaggtttc tgtttcgaag
    56941 gcttttcaac tacaatagct ttagtcgctt tcttcaacca cgtatcgcca tccatattag
    57001 tgaatgtagt tctgttgtaa tctaggaact ctaataatgt tggtttatct gtaattttac
    57061 caaagtattt ctcaaatgtt tttggactat tggttaatct taattcatca taactcatag
    57121 acccaaggta tgttaaccaa tctaaagaag taaggtcttt tttaccgaac gagcttggat
    57181 tataagctag aatatcacgg atattggtat ctccaaaatc aatattataa aaacgattga
    57241 tataggataa ccctagtaat attttctctt tattagcttc aatatcacct tttacttttt
    57301 ctctattttg ttgattgtca cctaaaatac tcaaggtatg cgccgcaact tttttcaaac
    57361 tagcttctaa atcggtttta gtcgcatcga gtgtttcttt aatagataat ttttcaagat
    57421 attcttttcg tagaatttct tttacttctt catcagttat cgccggatta gtttttcgta
    57481 attcttttcg ttttaagaat aaatctcgat ttatttctat atctgatgga gctaactgcg
    57541 cttttaactt ctcatttgtc aacaagtcta catttctcat ctccgcagta gcttccgtta
    57601 cgtttactgc attttctaat tcgctattaa ttgggagtaa atgaggtttg tcttctttag
    57661 tgccaaccaa gattactttt tggcgcatag ctttagttgt ttcagtcttc tctactggat
    57721 ttgttaactc tcctgtctcc ggattaactt cataagtttt agtgacggtt gtttcccctt
    57781 gttcacctgc atcctcaacc tcttcttttc ctttcggaag ttcagggtta tcttttctca
    57841 actcagtgat ttctataggt gacactatct tttccacatt tccaactttt actattttgt
    57901 ctttagctgg aatattttct attgtagttt cttctgagat agctcctgtt tcttgattta
    57961 ctgtgtattt tgtagttgat actgtacgcc ctttttcacc tggtgtttct tcttgttgca
    58021 cattgtaact taaatctggc gatgctttat aaactgtctt aaaaggaatt tcttgtgatt
    58081 gaactgttgg ttttgttcct actgccgtta ttttcgcttg catttctttg gctacttttg
    58141 ttgaaacttc tggctccgtc aagtctcctg tttgtgcatt tactttataa acacgaatag
    58201 tagtcgtttc ttcgtcctga ccttgatttc tgacttcttt gacaccttta tcaagtgact
    58261 catccgcgac aaactgttca cctcttttgg ttgttgaggt tgtttcttct acatttccaa
    58321 ccttaacaac tctatctact ggatgttttt ctatctttgt tgaagtgttt tctactattt
    58381 tcccagtact ttcatcaaaa ctgtaagaag tagttgtcac ttccttacca ttttcgcctg
    58441 ctacttctac ttgttgctct ttgtaattta aagctggcga tgctgtatag actgttttat
    58501 agtccaatac tttttctttc gttactggac tcgggacagt tggttgcact tgtgaatctg
    58561 actgctcttg gggagctgag ggttcaggct gaacagctgg agctggttcg tttccttgac
    58621 ttgggttgac ctctggagat ggagccgttt gttctggttg tttttggggt tcttgtgggg
    58681 cagattcacc agcatctttt gccccctcaa ctggattctc cagctggttc tcctcaccct
    58741 tttgttccgc aggagattga tcttcctctc gtcctgatcc cacggctggg cttgctagct
    58801 ctggttgctt cggctcggct tcgggtttgt caggtgtttg tttctcgccc ggcgtttctt
    58861 ctgctcctgg tcttggttgt cctattccag cagctggttt tgtctctgtt tcattctcta
    58921 ctattggttt tttctcaatt ttttcaggtt gaactggttt aacttcctct ggctctggag
    58981 ttacaggttg tgttggtttt ggtgcaactt cttccttagt cccaactgca atcaccttgt
    59041 tctccggctc ttttgtgact atattttcta taactttgct agatttttcc ccgttaacga
    59101 tagtgacttc cgtatagatg gtgcgttcac caacaacacc ttcttgaaca actttagttt
    59161 gccctttagc taagcttgca tcttcttgtt ctatcgtttg gaaagcaatc tcctctgtag
    59221 taactagcaa ttctggtttc tctactgtgg catttaacac gccttcctca ggacttggtt
    59281 tataatcact attattctct gctttcggtt gttctacttt gggatttcct gcaatttctt
    59341 ccttagtccc tataggcaca atttcatcag gagcttgttt gcttacagga gcttcaacaa
    59401 ttttctcaac tgcgtaggat ggttgaggag attgcacaaa atcttcagtc gagctaaaat
    59461 gagatgcagt ctgtggtaca atcttcttag attgaggttc tgaaccgtcc tcctttttag
    59521 ataatgctgg cgactctacc ttatcaacag aaagttcctt gttactactg tctcttacca
    59581 aataatatcc cgtaaattca tatccttgga ctctttcagg acttggtaga aactgacctt
    59641 ctaccctttt aacaagggcc ggttgcaatt ctaccagatt ttcgaaagca gagatggatg
    59701 ctccccatcc accaacagca aagactgtca caaggaagta agacgctccc ctttttctct
    59761 tgattaaagt gaaggaaagc aataataatc ctgctcccag gataaacgtc ccatcattag
    59821 aaaaaagacc tgtttctggt aatcttgtag ccaattttcg atagacaaag tagtattctt
    59881 ttccctcttt tacctcaatc ttattttctt caaaccattg caactcagat ttcagctttt
    59941 cagataaatc ctgctcatcc aaataatgac ttgaaattag tgttgaactc gtttcggtag
    60001 cctgtacagg ctgagcatcc ataccagcaa aaaataaact cgttcctagc aagaccgaac
    60061 aagctcctat tgcatatttc ctcaaagaaa aacgctgctt tcgctcaaat tgaaattctt
    60121 tcatcccatc tcccatcatt cattattact gtatatttag tatatcagaa atagtttgta
    60181 ttcacaaatc tttctagtta ttcccttatc attccaagtt aagggcaaca acatacaata
    60241 atttttattt aatactcttc gaaaatctct tcaaaccacg tcagcttcca tctgcaacct
    60301 caaaacagtg ttttgagcaa cctgcggcta gcttcctagt ttgctctttg attttcattg
    60361 agtataaatg tatatcaatg ttctttgttt ttcttaacaa acgcaacgca aaaagagcct
    60421 gttgccaagc tctttagtct attatttctt ctcagcgcgg agggctgaca agatttgtgt
    60481 acggatatca tccacaccat ttggcgtatt tggtaaaaag atcgtttgat ttcctttaga
    60541 agcaaaggta ttcaaggtat ccaagtactg gttggtcaag agaatggaca tgatttgttc
    60601 ttctgtcata ccaacattgg cttccttgag ttcggtgata gactctgcca atccatccac
    60661 aatcgcctta cgttgttggg caatccccac accatgaaga cgatcttttt ctgcttcggc
    60721 ttcagctgca gtgacgattt taatcttgtc ggcttctgcc aattcttgcg ctgcaacccg
    60781 cttacgttgc gctgcattga tttcattcat ggattgctta acttctgcat ctggttcgac
    60841 cttggtaatc aaggttttca cgataatgta gccataagtt gtcatttctt ctgctacttg
    60901 gtgttgaact tcaagggcaa tctcatcttt tttctcaaac aattcatcca aagttaattt
    60961 gggaacagaa gagcgaaggg cgtcttcaat ataagattta atctgagatt ctggacgcat
    61021 gagtttatag taggcatctg tcacgctctg ctcattgaca cggtactgag tcgctacatt
    61081 catcataacg aacacattgt ccttggtctt agtctcaacc acaatatcgc tttgcaacaa
    61141 acgcaactga atccgcgctg caatcgagtc gatcccaaaa ggcaagcgaa tatgaatacc
    61201 gctattggca accttttggt atttcccaaa gcgttcaata atcgccaccg actgctgacg
    61261 aaccacataa actgtgctca gtgtgactat cagcaatagg aacacacaaa caatcagaaa
    61321 aatcatgaaa aatattgcca taatggaacc tccacaagta tttttctagt attatagcac
    61381 atttaaagaa gactgtgcag tttttactgc gatttttcct gaaatgtcaa taattagagg
    61441 tgaagccaaa tttcaagtta ctaatctctt tttttcactg cattaacttc tatagaatct
    61501 tcatccatag tcagagaatg acttgcctta atttttctct cgtgctatac tatttatgaa
    61561 attaatgaat aggagatatt tcatgaaatc agcaaaaact actgttacaa tcctttctgc
    61621 acttgcatct gtcgtcttat tatctagttg tgcaacaaag tctacagaaa cacagacaag
    61681 caataagagc tcatctgata atcagattac aatgacatat gaccaactac ggtcaagaga
    61741 aaatactatg tcaacccttt ggtattaaaa atcagctgaa accaaagcct tgtatctaca
    61801 aggttataat gttgccacag atcgtctaaa ggaattactg aaaacagaat cagacaagcc
    61861 ttattcaatc gttttgaact tagatgaaac agtcttagat aatagtcctt atcaagttca
    61921 aaatatcaaa gacggaacag cattcacacc tgaaaattgg gatatttggg ttcaaaaagc
    61981 tgcagcaaaa gccgtcccag gagctaagga gtttcttcaa tttgccaatc aaaacggcat
    62041 ccaaatttac tatatttctg accgctcagt taatcaaata gatgctacga ttaaaaatct
    62101 agaaaacgaa ggaatccctg tacaagggcg tgatcacctc atgctcttag aaagtggtgt
    62161 aaaatccaaa gaagggcgtc gccaagcagt tcaagagaaa actaatctag tattactatt
    62221 tggtgataac ctcgtagact ttgcagattt ttcgaagact tctgaatctg accgtgataa
    62281 acaacttgaa gaattgcaaa aagaattcgg tgaaaaattc atcatcttcc caaattcaat
    62341 gtacggatca tgggaaacaa ctgtctacgc tggcaataaa ttggatgcta aaggtcaagt
    62401 ggaagaacgc caaaaggctt tgcaaggttt taataaataa aacaaataag ctgattctat
    62461 ataaactaag gctaacttac aatcttcaaa aagtggatag gaaggaattc tgataatcag
    62521 aaaactttcc tatccacttt ttgaattgat ataacatcaa gcttttatac atctgatact
    62581 atatgttttt tgattttaaa gactttttgc ctatccccta tatttcaaga attaagcaat
    62641 cttgatgatc taaatttgtt gtgatataat atttttgtca tcggttaccg attacgttcc
    62701 tatgggttcg tgagaggagg tgaaactaat ga
//
LOCUS       DAVDZK010000007        58979 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVDZK010000007 DAVDZK010000000
VERSION     DAVDZK010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58979
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.007"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            22..1305
                     /gene="aroA"
                     /locus_tag="VUX16_000505"
     CDS             22..1305
                     /gene="aroA"
                     /locus_tag="VUX16_000505"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET8123531.1"
                     /translation="MKLKTNISHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVVTIQGVGMDGLKAPQNALDMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTIPLKKMGVSISGQTERDLPPLHLKGTKKLAPIQY
                     ELPIASAQVKSALMFAALQAQGESVIIEKECTRNHTEDMLQQFGAHLSVDGKKITVQG
                     LQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EVTEIDLVAKSATLTVESSDLQGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTVDGMIVKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVSDGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            1298..1774
                     /locus_tag="VUX16_000506"
     CDS             1298..1774
                     /locus_tag="VUX16_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET8123532.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGISIANFFA
                     EKGESAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIATDKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            1771..2619
                     /gene="pheA"
                     /locus_tag="VUX16_000507"
     CDS             1771..2619
                     /gene="pheA"
                     /locus_tag="VUX16_000507"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET8123533.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQTVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAGKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            2616..3890
                     /gene="psr"
                     /locus_tag="VUX16_000508"
     CDS             2616..3890
                     /gene="psr"
                     /locus_tag="VUX16_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET8123534.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTIDARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINCRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFGLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            4169..5014
                     /locus_tag="VUX16_000509"
     CDS             4169..5014
                     /locus_tag="VUX16_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET8123535.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLICYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTVFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            5004..6107
                     /locus_tag="VUX16_000510"
     CDS             5004..6107
                     /locus_tag="VUX16_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET8123536.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTINS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            6109..7095
                     /locus_tag="VUX16_000511"
     CDS             6109..7095
                     /locus_tag="VUX16_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET8123537.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQRQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            7111..8580
                     /locus_tag="VUX16_000512"
     CDS             7111..8580
                     /locus_tag="VUX16_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET8123538.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFVARKKIKVANIGSSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNIQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVMIFVAKILTKENQYLLNKGEKNHV"
     gene            8573..9607
                     /locus_tag="VUX16_000513"
     CDS             8573..9607
                     /locus_tag="VUX16_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET8123539.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            9807..10544
                     /gene="mecA"
                     /locus_tag="VUX16_000514"
     CDS             9807..10544
                     /gene="mecA"
                     /locus_tag="VUX16_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET8123540.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            10695..11981
                     /locus_tag="VUX16_000515"
     CDS             10695..11981
                     /locus_tag="VUX16_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET8123541.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHSAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILATDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            11983..12852
                     /locus_tag="VUX16_000516"
     CDS             11983..12852
                     /locus_tag="VUX16_000516"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET8123542.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            12928..13005
                     /locus_tag="VUX16_000517"
                     /pseudo
     CDS             12928..13005
                     /locus_tag="VUX16_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            13147..14085
                     /gene="msrB"
                     /locus_tag="VUX16_000518"
     CDS             13147..14085
                     /gene="msrB"
                     /locus_tag="VUX16_000518"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET8123543.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            14145..15869
                     /locus_tag="VUX16_000519"
     CDS             14145..15869
                     /locus_tag="VUX16_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123544.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRNRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELAFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            15871..17619
                     /locus_tag="VUX16_000520"
     CDS             15871..17619
                     /locus_tag="VUX16_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123545.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRGRII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDTFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            17921..19180
                     /locus_tag="VUX16_000521"
     CDS             17921..19180
                     /locus_tag="VUX16_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET8123546.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    19256..19391
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            19430..19930
                     /locus_tag="VUX16_000522"
     CDS             19430..19930
                     /locus_tag="VUX16_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET8123547.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARSLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            20006..20374
                     /gene="rplL"
                     /locus_tag="VUX16_000523"
     CDS             20006..20374
                     /gene="rplL"
                     /locus_tag="VUX16_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET8123548.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DATDAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            20576..20749
                     /locus_tag="VUX16_000524"
     CDS             20576..20749
                     /locus_tag="VUX16_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123549.1"
                     /translation="MTKELQSSRHIVISFLVREMGIDIVEAISLMAELEKSGLVRLES
                     SGDLILKELGGAL"
     gene            20746..21525
                     /locus_tag="VUX16_000525"
     CDS             20746..21525
                     /locus_tag="VUX16_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET8123550.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKTLKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVGNSNRPSVKKRLGQDENDTAPVSHLAPSETEVSETKYSE
                     TDSLFIEDEEERNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            21624..22982
                     /gene="dcm"
                     /locus_tag="VUX16_000526"
     CDS             21624..22982
                     /gene="dcm"
                     /locus_tag="VUX16_000526"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET8123551.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARESYKSIFQT
                     EGEIEFHDIRDVSDDEFKKLRGKVDVICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQVLNSKDFGVPQNRE
                     RVFIIGHSRKKGTRLLFPFRREGQATNSETLKALGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLEKRQNGRRFKDNQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYQVAGILIDGQFYRLRIRR
                     ITPKECFRLQGFPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDES
                     IK"
     gene            22966..23415
                     /locus_tag="VUX16_000527"
     CDS             22966..23415
                     /locus_tag="VUX16_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123552.1"
                     /translation="MKALNRESILDCDELETELHDAEIKQLDEQIFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFVDDNQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKQPINFANLLDSLIVSEYQMEPNLWEVSHD"
     gene            23408..23788
                     /locus_tag="VUX16_000528"
     CDS             23408..23788
                     /locus_tag="VUX16_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123553.1"
                     /translation="MIDLYLSKNNHRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            23801..24034
                     /locus_tag="VUX16_000529"
     CDS             23801..24034
                     /locus_tag="VUX16_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET8123554.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            24037..24624
                     /locus_tag="VUX16_000530"
     CDS             24037..24624
                     /locus_tag="VUX16_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET8123555.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILQILYGASLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGIGFISLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGLVRYKSDLWGSMGLHLVWNLSVYVLFLL"
     gene            25001..25315
                     /locus_tag="VUX16_000531"
     CDS             25001..25315
                     /locus_tag="VUX16_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET8123556.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            25331..25717
                     /locus_tag="VUX16_000532"
     CDS             25331..25717
                     /locus_tag="VUX16_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET8123557.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            25746..27128
                     /locus_tag="VUX16_000533"
     CDS             25746..27128
                     /locus_tag="VUX16_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET8123558.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLHL
                     EKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEYD
                     KLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRKE
                     DLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTKE
                     NTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYGM
                     MFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQA
                     TCEAEVAGVD"
     gene            27131..27283
                     /locus_tag="VUX16_000534"
     CDS             27131..27283
                     /locus_tag="VUX16_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET8123559.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            27306..28511
                     /locus_tag="VUX16_000535"
     CDS             27306..28511
                     /locus_tag="VUX16_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HET8123560.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            28554..28775
                     /locus_tag="VUX16_000536"
     CDS             28554..28775
                     /locus_tag="VUX16_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123561.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            28892..29389
                     /locus_tag="VUX16_000537"
     CDS             28892..29389
                     /locus_tag="VUX16_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HET8123562.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            29364..29870
                     /locus_tag="VUX16_000538"
     CDS             29364..29870
                     /locus_tag="VUX16_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET8123563.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            29854..32301
                     /locus_tag="VUX16_000539"
     CDS             29854..32301
                     /locus_tag="VUX16_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET8123564.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            32304..34481
                     /locus_tag="VUX16_000540"
     CDS             32304..34481
                     /locus_tag="VUX16_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET8123565.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            34478..35479
                     /locus_tag="VUX16_000541"
     CDS             34478..35479
                     /locus_tag="VUX16_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET8123566.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            35476..36411
                     /locus_tag="VUX16_000542"
     CDS             35476..36411
                     /locus_tag="VUX16_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET8123567.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            36655..36771
                     /locus_tag="VUX16_000543"
     CDS             36655..36771
                     /locus_tag="VUX16_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET8123568.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            36787..38706
                     /gene="tet(M)"
                     /locus_tag="VUX16_000544"
     CDS             36787..38706
                     /gene="tet(M)"
                     /locus_tag="VUX16_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET8123569.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            38825..38992
                     /locus_tag="VUX16_000545"
     CDS             38825..38992
                     /locus_tag="VUX16_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET8123570.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(39052..39189)
                     /locus_tag="VUX16_000546"
                     /pseudo
     CDS             complement(39052..39189)
                     /locus_tag="VUX16_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            39605..39688
                     /locus_tag="VUX16_000547"
     CDS             39605..39688
                     /locus_tag="VUX16_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HET8123571.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            39813..40550
                     /gene="erm(B)"
                     /locus_tag="VUX16_000548"
     CDS             39813..40550
                     /gene="erm(B)"
                     /locus_tag="VUX16_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HET8123572.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            40905..41459
                     /locus_tag="VUX16_000549"
     CDS             40905..41459
                     /locus_tag="VUX16_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002402802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET8123573.1"
                     /translation="MIFGYARVSTDDQNLSLQIDALTHYGIDKLFQEKVTGAKKDRPQ
                     LEEMINLLREGDSVVIYKLDRISRSTKHLIELSELFEELSVNFISIQDNVDTSTSMGR
                     FFFRVMASLAELERDIIIERTNSGLKAARVRGKKGGRPSKGKLSIDLALKMYDSKEYS
                     IRQILDASKLSKTTFYRYLNKRNA"
     gene            41463..44381
                     /locus_tag="VUX16_000550"
     CDS             41463..44381
                     /locus_tag="VUX16_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HET8123574.1"
                     /translation="MAMKRILTTSQREQLLSVDHLSEEDFKAYFSFSDYDLEVINQHR
                     GKVNKLGFAIQLCLARYPGCSLSNWPIKSTRLTSYVSRQLHLDAIDLNSYDHRNTRAN
                     HFNEILEVFNYHRFGSANTQKQLIEYLIELALENDDSIYLMKKTIDFLTRKRIIFPSI
                     ATLEDIISRCRDKAENNLFSILLCSLTDIQIEKLESLFQIYEETKITKLAWLKDIPGK
                     ANPESFMSICKKVEVIASMGLGTINVSHINRNRFLQLARLGENYDAYDFSRFELEKRY
                     SLLIAFLVNHHQYLIDQLIEINDRILASIKRKGTRDSQEQLKEKGKLATKKLEHYASL
                     IDALHFAKDNDSNPFDEIERIMPWEDLVQDGEEAKKITGNKNHGYLEMVRNKANYLRR
                     YTPMLLRTLSFKATPAANPVLMALTQLTDLHNSGKRKIPADTSTDFVSKKWKSLVRPE
                     EGKIDRSYYELVAFTELKNNIRSGDISVEGSMIHRNIDDYLVDLSACIDSETIPDTFE
                     DYLKDREIILDLQLQFYSTVDKRISRANLKKLEKVTPSEAEIYRKKLYSIIPKIRLSD
                     LLIEVDSWTNFSQEFSHDSTGKPPSEQERKIIFAALLGLGMNIGLEKMAQSTPGISYS
                     QLANAKQWRFYKEALTRAQSVLVNYQLKLPVADFWGEGKTTASDGMRVPVGVSALKSD
                     VNPHYKSMEKGATMIRSINDRHTTHHIEVASTNTREATHTLDGLLYHETDLDIEEHFT
                     DTNGYSDQVFGMTALLGFDFEPRIRNIKKSQLFSIKSPSYYPNLSEDISGKINVKIIE
                     ENYDEIKRIAYSIQTGKVSSSLLLGKLGSYARKNRVALALRELGRIEKSIFMIDYITD
                     SELRRRITHGLNKTEAINALARELFFGRRGKFMERDIRRQLQSASALNVLINAISIWN
                     AVYLQAAYNYLVKIDPEVTKYMKHVSPINWEHITFLGEYKFDLLSIPKHLRELNIKNK
                     "
     gene            complement(44455..44676)
                     /locus_tag="VUX16_000551"
                     /pseudo
     CDS             complement(44455..44676)
                     /locus_tag="VUX16_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            45181..45603
                     /locus_tag="VUX16_000552"
     CDS             45181..45603
                     /locus_tag="VUX16_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET8123575.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            45600..45830
                     /locus_tag="VUX16_000553"
     CDS             45600..45830
                     /locus_tag="VUX16_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET8123576.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            46291..46494
                     /locus_tag="VUX16_000554"
     CDS             46291..46494
                     /locus_tag="VUX16_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET8123577.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            46576..47793
                     /locus_tag="VUX16_000555"
     CDS             46576..47793
                     /locus_tag="VUX16_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET8123578.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            48063..48653
                     /locus_tag="VUX16_000556"
     CDS             48063..48653
                     /locus_tag="VUX16_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET8123579.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVAEGKIDA
                     EEKGLYRLPDIYLDEWFVLQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEVERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNKIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            48653..49489
                     /locus_tag="VUX16_000557"
     CDS             48653..49489
                     /locus_tag="VUX16_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HET8123580.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIHIFEEILCSNTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AEKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISFDNSVQVIREIMQQ
                     IF"
     gene            49772..50071
                     /locus_tag="VUX16_000558"
     CDS             49772..50071
                     /locus_tag="VUX16_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123581.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIVDGKAVEVTLREPYSRDLLQVVKSIKQRQKLIAYRYKEGKLLFVKKEASDVL"
     gene            50061..50549
                     /locus_tag="VUX16_000559"
     CDS             50061..50549
                     /locus_tag="VUX16_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123582.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYSIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     TKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            50549..52426
                     /locus_tag="VUX16_000560"
     CDS             50549..52426
                     /locus_tag="VUX16_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET8123583.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGQEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQETDERWWNYQINPLNQRQENHLEGLRIRDLTFESSL
                     K"
     gene            52447..52689
                     /locus_tag="VUX16_000561"
     CDS             52447..52689
                     /locus_tag="VUX16_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123584.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            52706..53560
                     /locus_tag="VUX16_000562"
     CDS             52706..53560
                     /locus_tag="VUX16_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET8123585.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTISGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            53614..53973
                     /locus_tag="VUX16_000563"
     CDS             53614..53973
                     /locus_tag="VUX16_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET8123586.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            53966..56281
                     /locus_tag="VUX16_000564"
                     /pseudo
     CDS             53966..56281
                     /locus_tag="VUX16_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241830.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            56293..>58979
                     /locus_tag="VUX16_000565"
     CDS             56293..>58979
                     /locus_tag="VUX16_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET8123587.1"
                     /translation="MKDKREIIRARKAFRRSLKDEKKFLKQGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSFLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKESRKERKTNQKFLYGQESKQKSNFFFQGKSLEELKAKKE
                     VKAAKENLKSTKQAYKYKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     FRKLKKQGLSSVQNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELQKPV
                     HLFSSETYKDYLSTLWHDLNDGDDLKSMQDLYETPKYKLSKDDQEEIKELKEEGVYAS
                     MQELDNPFEGQSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQTIVAPMDAVVSL
                     DGDNIILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDIIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYDFLKSQGVSPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATDSSWDDESWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTSDGSTRYTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPADYGHVAFV"
BASE COUNT        18974 a        10333 c        12365 g        17307 t
ORIGIN      
        1 attgcaagta tgaggtccag tatgaaacta aaaacaaaca ttagccactt acatggcagt
       61 atccgcgtcc caggtgacaa gtctatcagc caccgttcca ttatctttgg aagtttagct
      121 gagggagaga ccaaggttta tgatattttg cggggtgaag acgtcctttc aaccatgcag
      181 gtctttcgtg atcttggtgt agagattgag gataaagatg gggttgttac cattcaaggt
      241 gtcggtatgg acggcctaaa agctccacaa aatgcccttg atatgggaaa ttctggaacc
      301 tcgattcgtc tgatttcagg tgtccttgct ggtgcagact tcgaagtaga aatgttcgga
      361 gacgatagtc tttccaaacg tcctatggac cgtgtgacga ttccactgaa aaaaatgggc
      421 gttagcattt cagggcaaac tgagcgagac ttgcctcccc ttcacttaaa agggacgaaa
      481 aaactagcac ctattcagta tgagttgcca attgcctctg cccaagtcaa gtcagccttg
      541 atgtttgcgg ccttgcaggc tcagggagag tcagtgatta tcgaaaaaga atgcacccgt
      601 aatcatactg aagatatgct gcaacaattt ggtgctcatt taagtgtgga tggcaagaaa
      661 atcacagtcc aaggacttca aaaactgaca ggacaaaagg tggttgttcc aggagatatt
      721 tccagtgcag ccttttggtt ggtcgcaggt ttgattgttc cgaattctcg tctagtgctg
      781 cagaatgtgg ggattaacga aacgcgtacc ggtattattg atgtcattcg tgccatgggt
      841 ggaaaattag aagttactga aattgaccta gtggctaaat ctgctacttt gactgttgag
      901 tcttctgact tgcaaggaac agagattggc ggtgccttga ttccacgctt gattgatgaa
      961 ttgcctatta ttgccctttt ggcgacccaa gcccaaggtg taacagttat caaggatgct
     1021 gaggagctca aggtcaagga aacagaccgt attcaggttg tggcagacgc cttaaatagt
     1081 atgggagcag atattactcc tacggtagat gggatgattg tcaaaggaaa atcagctctt
     1141 cacggtgcta gagtcaatac gtttggtgac caccgtatcg gcatgatgac agctatcgca
     1201 gccctcttgg tttcagatgg agaggtggag cttgaccgtg cagaagccat caataccagc
     1261 tatcctagtt tctttgatga tttggagagc ttgattcatg gctaaggtgt tattagggtt
     1321 tatgggggct ggaaaatcga ctattgcaag aggattggac cctaattacc ttgatatgga
     1381 tgctctgatt gagaagcgcc taggtatatc cattgcgaat tttttcgctg aaaagggaga
     1441 atcagccttt cgtcaggtag aatcagaagt cctagctgat ttactacaaa cagaccaagt
     1501 cgtgtcaact ggaggaggag tggttatttc tcagagaaat cgtgacttac tcaagactaa
     1561 tacagataac atctacctga aagcagattt tgaaaccctc tacctacgta tcgcaactga
     1621 taaggacaat cagcgaccgc tttttctaaa taatagcaag gaagaactag tagctatttt
     1681 tcaagaaaga caggcttggt atgaggaagt ggctagtcgg gttttggatg tgaccaagct
     1741 aagcccagag gaaattatag aggaactaag atgaaaattg cttatctagg tcccaaggga
     1801 tcattttcac accacgttgt gcagacagct tttcctcatg aggaattgca ggcttttgcc
     1861 aacattacag atgtcatcaa ggcttatgag caaggattag tggactattc tgtggtgcca
     1921 gttgaaaact ctattgaggg tagtgttcat gaaaccttgg actatctttt tcatcaggct
     1981 cacatccaaa cagtagcaga aatcgttcag cctattcatc agcagttgat ggtggttcca
     2041 ggccatacta agattgaaaa gattttttca catccacagg cattggctca aggaaagaaa
     2101 ttcatcgatg aacaatatcc agaggctcaa atcgaggtaa cagctagtac agcttatgcg
     2161 gcccgtttta tttccgaaca tccagaccag ccctttgcag caattgcacc tagaagttct
     2221 gctgaagaat atggattgga actgattgcc gaggatattc aggaaatgga agccaatttc
     2281 acacgtttct gggttctagg agctggaaag cctagtattc ccttgcaagc acaaactgaa
     2341 aagatgagtt tggccttgac attacctgac aaccttccag gtgcacttta taaggccctg
     2401 tcgacctttg cttggcgagg aattgacttg acaaaaattg aaagtcgtcc actcaagaca
     2461 gcactgggtg aatacttttt tattatcgat gtggattata ccgataagga cttggtccac
     2521 tttgcccaaa aagaattaga agcgattgga atccagtata aaattctggg cgcctatcct
     2581 atttatccaa tatcagacca tggaaaggag agaagatgag taaagaaaat cccttaagtc
     2641 atcatgagca gttgcgttat gattatttgc taaaaaatat tcactatctc aatgagagag
     2701 aaaaaaatga gtttgcctat ttgcaagaaa agctaactct tgctagggga aatagtagct
     2761 ctagcttgga acaagaaaga gaagagcagg ttgacttacc aagctatgcg aaccggagtc
     2821 gctcacaatc caaatcacaa gcactctctt cacctccaaa aaagaaaaga cggaagctcc
     2881 gtcttaaacg aatttttatg gtgatttttt cacttttagt ctgtgtggct ttggccatgg
     2941 tattcatgtt tttgcgtggt taccaagatg ctagcgcaaa gaaaactatt gatgcccggg
     3001 cagctcaagt agaagtcttt aatggtcagg acactagaga tggagttaat attttaatca
     3061 tgggtactga tggtcgaatc ggccagaaca gtgttgagac acgaactgac tctattatgg
     3121 tattaaatgt cgggggctca gataagaaaa tgaagctagt cagtttcatg cgtgataatt
     3181 tggtctatat agatggttat agtcaagtga ttaactgtag aaaacagaca gataacaagt
     3241 taaacgtagc ctacgagtta ggagaacaag aggggcaaaa aggggcagaa atggttcgcc
     3301 aagtcttgaa agataatttt ggcttggaca ttaagtacta tgccttggtt gatttccagg
     3361 cctttgccac agcgattgac acgcttttcc ctgatggggt gacgattgat gctcaatttt
     3421 caacattgaa tgggcgtccc ctaacagaag ctacagtcgg agatgattta tacgctaccg
     3481 agactgagtc tccaacccaa accattaaag tcggaaaaca gcagatgaat ggctcgaccc
     3541 tgctcaatta tgctcgtttc cgtgatgatg atgaggcgga ttacggccgt acaaaaagac
     3601 agcaacaagt tttaacagca attttagagc aaattaaaga tcctactaaa cttttcactg
     3661 gttctgaagc tcttggaaag gtttttgcta tgacctcaac caacgtaccc tatactttcc
     3721 tcctaacaaa cggtttatct gttttggatg gagcaaaaaa tggtattgaa aaattgacga
     3781 ttccagaact gggtgactgg gtagatgcct atgatgttta tggaggcttg ggcttgctgg
     3841 ttgatcaaaa caaatatcaa accaagctcg ctcaaatggg cttgagataa gataatactc
     3901 aatgaaaatc aaagtgcaaa ctaggaagct agccgcaggc tgctaaaaac acagttttga
     3961 ggttgtagat aagactgacg aagtcagtta cctataccta cggcaaggtg aagctgacgt
     4021 ggtttgaaga gattttcgaa gagtataaga cagaaaaatc aaagtttgat agctatttgg
     4081 atagcagtca ggctttgatt ttttacagtc tgcaatagat tttcacccct tgtttgtggt
     4141 ataatgaaac gatacgatag aaagaataat gaacaatatg actgatttaa aagcaattca
     4201 ggctcgtagt ctggagatgg ctgaatattt tgtggccttt tgtaaagaac atgatttgat
     4261 ctgttatctc tgtggcggag gcgctattgg tgcccttcga aacaagggat ttattccttg
     4321 ggacgacgac ctagactttt ttatgcctcg taaagattat gagaaattag cagaattatg
     4381 gcctcgttat gcagatgaac gttatttctt gtcaaagagt cacaaggatt ttgttgatcg
     4441 taatcttttt attaccattc gtgacaagga aaccacctgt atcaagcctt atcagcagga
     4501 tttggatttg ccacatggtc tggccttgga tgttttgcct ttggattatt atccgaaaaa
     4561 tccagctgag cggaaaaaac aggttcgttg ggccttgatt tattcactct tttgtgcgca
     4621 aactattcca gaaaagcatg gtgctcttat gaaatgggga agtcgcattt tactgggttt
     4681 gactccaaaa tctctccgtt atcgcatctg gaaaaaagct gagaaagaaa tgactaagta
     4741 tgatttggct gattgtgatg gcattacaga attatgctca ggtcctggct acatgagaaa
     4801 caagtaccca atcacatctt ttgaagacaa tcttttcttg ccatttgaag gaacagagat
     4861 gcctattcca atcggctatg atgtctatct cagaactgtt tttggggatt atatgacgcc
     4921 tccaccagca gacaagcagg taccgcatca tgatgctgtc atcgctgata tggataagtc
     4981 ttatacagaa tacaagggag aatatggtgg ctaagaaaaa aatcttattt tttatgtggt
     5041 ctttttctct tggaggtggt gcagagaaga ttctatcaac cattgtttca aatctggatc
     5101 cagaaaagta tgatattgat attcttgaaa tggagcactt tgacaaggga tatgaatctg
     5161 ttccaaagca tgtacgcatt ttaaaatccc ttcaagatta tcgccaaacc agatggttac
     5221 gagctttttt gtggagaatg agaatttatt ttccaagact gactcgtcgt ttgcttgtaa
     5281 aagatgatta tgatgttgaa gtttctttta ccattatgaa tccaccactg ttgttctcta
     5341 aaagaagaga agtcaagaag atatcttgga ttcatggaag tattgaagaa cttcttaagg
     5401 atagctctaa aagagaatca catagaagcc agttggatgc tgcgaataca attgtaggga
     5461 tttcaaaaaa gaccatcaat tctatcaagg aagtttatcc agattatgct tctaaattac
     5521 agacaatcta caatggatat gattttcaga ctattctaga aaaatctcaa gagaagatcg
     5581 atatcgagat tgctcctcaa agtatctgta ctatcggacg gattgaggaa aataagggtt
     5641 ctgaccgtgt agtggaagtg atacgattat tacaccaaga gggaaaaaac tatcatctct
     5701 attttatcgg ggctggtgat atggaagagg aactgaaaaa acgagtcaaa gagtatggga
     5761 ttgaggacta tgtacatttc cttggttatc aaaaaaatcc ttatcagtat ttatctcaga
     5821 cgaaagttct cttgtctatg tctaaacaag aaggttttcc tggagtgtat gtggaggcct
     5881 tgagtctggg actccctttt atctctacgg acgttggagg ggctgaggaa ttatcccaag
     5941 aaggacgatt tggacaaatc attgagagca atcaagaggc agctcaggcg attactaatt
     6001 acatgacttc tgcctcaaac tttgatgtcg atgaggctag ccaattcatt caacaattta
     6061 caattacaaa acaaatcgaa caagtagaaa aactattaga ggagtagcat ggaaactgca
     6121 ttaattagtg tgattgtgcc agtctataat gtggcgcagt acctagaaaa atcgatagct
     6181 tccattcaga ggcagaccta tcaaaatctg gaaattattc ttgttgatga tggtgcaaca
     6241 gatgaaagtg gtcgcttgtg tgattcaatc gctgaacaag atgacagggt gtcagtgctt
     6301 cataaaaaga acgaaggatt gtcgcaagca cgaaatgatg ggatgaagca ggctcacggg
     6361 gattatctga tttttattga ctcagatgat tatatccatc cagaaatgat tcagagctta
     6421 tatgagcaat tagttcaaga agatgcggat gtttcaagct gtggtgtcat gaatgtctat
     6481 gctaatgatg aaagcccaca gtcagccaat caggatgact attttgtctg tgattctcaa
     6541 acatttctaa aggaatacct cataggtgaa aaaatacctg ggacgatttg caataagcta
     6601 atcaagagac agattgcaac tgccctatcc tttcctaagg ggttgattta cgaagatgcc
     6661 tattaccatt ttgatttaat caagttggcc aagaagtatg tggttaatac taaaccctat
     6721 tattactatt tccatagagg ggatagtatt acgaccaaac cctatgcaga gaaggattta
     6781 gcctatattg atatctacca aaagttttat aatgaagttg tgaaaaacta tcctgacttg
     6841 aaagaggtcg cttttttcag attggcctat gcccacttct ttattctgga taagatgttg
     6901 ctagatgatc agtataaaca gtttgaagcc tattctcaga ttcatcgttt tttaaaaggc
     6961 tatgcctttg ctatttctag aaatccaatt ttccgtaagg ggagaagaat tagtgctttg
     7021 gccctattca taaatatttc cttataccga ttcttattac tgaaaaatat tgaaaaatct
     7081 aaaaaattac attagaacgg gggtgaccaa gtgattgatg ggaaacgatt attatttagt
     7141 ttgaccatag tcagttatgc cttgacgcta gtaagtggaa ttgtgtatct gtttaataat
     7201 aataatgtta gcttactttc tactttattg ttcttgttgg ttagtagctt aattgcttgt
     7261 tggaatgata tcaagtatta cttaatccat tttattttct atttaaccat ttttgtattt
     7321 ctggtatcaa gaccgaccat tgattatttt agggatggtg ctttggatac ctatcatcca
     7381 atagcctatc gttttgcctt catagttgtc atggtttcga ttctgggctt gactacagga
     7441 ggcgtcctgg ctcgttactt cgtagctagg aagaaaataa aagtagcaaa tataggaagt
     7501 tctctaaaag aggtttatat caagcggtta cgctttgtat cactaggagt ttttcttcta
     7561 acttatcctt tctatttcat tcggttattt gaacggctct tgtatcgttt gcagacttcc
     7621 tactatgcct actatgcaaa ttttgaaagt aaactgcctt attttaccta cattttgtct
     7681 acctttacgg tctatgcaat gtgtatgtat ctggcaacca agccaaagaa attgcaggcc
     7741 acagcagtgc ttgtctcctt tattgcagct aatactattc atttggcaat tgggacacga
     7801 aatcccttta ttttaagtat tttatttgct tttgtttatt actttatgcg ggagcaaact
     7861 gaaaaaggaa aatggattgg gtttaaagaa aagttagcga tttttgtagg ttctcctatt
     7921 ctcatgttag cgatgggagt actcaattat gtacgggata atatccaagt ttcccataca
     7981 ggtttctggg atatcttact tgactttatc tataaacaag ggactagttt tggtgttctg
     8041 gctcgaggtt ttctatttaa cagtagcctc ccttaccgag atttccgtaa ttttactttt
     8101 ggtcctgttc ttgattattt tgcaaggggg agtttgggag ccattttcgg aggaaaagcc
     8161 tttgaacata caaccaatag tgtggaacta gctattgata gtaatagtta tgcccacaat
     8221 ctatcctatc ttgtcttgaa caaggaatac ttgaaagggc atggtatcgg aagtagttat
     8281 atcatggagt tgtataccga ctatggtatg attggagtct ttctgcttag tttcttactc
     8341 ggcgtattat ttatagccat gctgcaagta gcctatcgct caaggacaat cctatttgct
     8401 ttatccctac tcatcttgaa taatctattc tttatgccaa gaagcagctt ttcagaaagt
     8461 ttcttcaatt tatttacaat gcaattctgg ggaattgttc ttgtgatgat attcgtagca
     8521 aaaatactta caaaagaaaa ccagtatcta ctaaacaaag gagaaaaaaa tcatgtttga
     8581 acattattca gtagctgatt tatttgcaaa tctatacaaa aaacgaaaag caaatattct
     8641 agctctcatc gctttatttg ctctcattgc tgtaccattt acaattaaag cagttaggaa
     8701 taaaaacact gtcaaagata caacaagtta ttcaacttat cttatctata aaatcactcc
     8761 tccagaagat tcggccaaaa cgattttgaa tcatcaaatt ggtggttata gtgattttta
     8821 tgggaaattg attgatggta atttgaatgg agcttatctt ttcaatgatg tagaacccag
     8881 tgagttgaaa aaaattgcca gtgaattaga cacgacagaa acaaccttga aaaattcaac
     8941 gaatgactat tggtggaaaa aattgaccgt ctactatatg attgacgatg caggggttgg
     9001 tgtgaaaatt ttgacatcaa gtaaagatgc caatgacttg ttagagaaaa aaattgatgg
     9061 gttgattgag aaatttaaac atgcctatgc aaatgtgaaa attgaaaaac tggaaaccat
     9121 caactctaaa gaattgaacg caaatggtga aacagcgctt ggcttaaatg tgaaaaatct
     9181 gattcttcgt ttagttgtta ttggagtggt ttgtgtgatt ttggttgtga tgggaaatgt
     9241 gttagtttat ctctttaatc caacaatcaa tagagtaggt gatttttctc agtatcaaat
     9301 tgattttgta acagagatta caacaattgc taacctagca gatgttttgt catacaaaaa
     9361 tactggacag gaattgacca tcgttagctc aaataaagct atcctagata aattgaaaca
     9421 gagtcaagaa gctttaaaag gaatgcattt tgtagattta caggatgtat catctctttt
     9481 ggaaagagat acagtccttc ttgttgaaga gtacggagtg actcgttata agaaatttga
     9541 gcaaagtctt caaattctca gaaacttaaa tcgttctatc ctcggcgtag caacctttaa
     9601 attataagta ttctgatgta taaggtcttc aaagtcggct aagagccgat tttgaaggct
     9661 ttttctatct gtctgcagaa attttctttt ggagtctcct atagaaagac cctagggaaa
     9721 atctatccgt atagaggagc cttcttttga taaaatcgta aaaatctagt ataatagata
     9781 gaactgaaag tatgaggtta ctagcaatga aaatgaaaca aattagtgat acaactttaa
     9841 aaatcacgat gtctttagag gatttgatgg atcgtggaat ggagattgct gactttctcg
     9901 ttcctcaaga aaaaacagaa gagttctttt atgctatctt ggatgagcta gagatgcctg
     9961 atagctttct ggatacaggc atgttgagct tccgtgtgac tccaaaacct gataaggtag
    10021 atgtctttgt gaccaagtca aagattgacc aaaatctaga ttttgaagac ttatcggatt
    10081 tgccagatat ggaagaattg gctcaaatgt ctccagatga atttatcaaa accctggaaa
    10141 aaagcatcgc agacaaaacc aaggatgata tcgaagccat tcaatctctt gagcaagttg
    10201 aagccaagga agaagagcaa gagcaagctg aacaagaagc tgagagtaag aaagaacctt
    10261 acatctacta catcctttct tttgctaagt tggctgactt ggtagctttt gccaagacag
    10321 tgacttttga aatggaaact tctgaactct acaaaatgaa cgagcgctat tatttgacca
    10381 ttttagtgga tattgaaaat catccaagcc catatccagc ttggctgttg gcccgtatgc
    10441 gcgagtttgc agacgatagt gatatcagtc gctcagtctt acaagagtat ggtcaagtct
    10501 tgatgagtca cgatgcagtg ctcaatctgc aaaaaatcgg ctaatccttt ctggaaagct
    10561 attttcagat tttaagaaga gcgaatcgtc tgattcgttt tttcttttta tactgaaata
    10621 gtgatttact ataataggaa ttttcacaaa attctgttat aatggctata ttagaaaatt
    10681 tcgaggagat aaagatgaca gttaaaattg ctttactagg atttggtacc gttgcaagtg
    10741 gtgtgccttt cctcctaaag gaaaatggag gaaaaatcaa tcaatcagca cattcagata
    10801 tcaaagttgc taaggtattg gtcaaggatg aagatgaaaa aaatcgcttg cttgcagcag
    10861 ggaatgactt taactttgta accaatgtgg atgatatttt atcagaccaa gatattacta
    10921 tcgtagtgga attgatgggg cgtattgagc ctgctaaaac ctttatcact cgtgccttgg
    10981 aagctggaaa acacgttgtt actgctaaca aggacctttt agctgtccat agcgcagaat
    11041 tgctagaaat cgctcaagct aacaaggtag cactttacta cgaagcagca gttgctggtg
    11101 ggattccaat tcttcgtact ttagcaaatt ccttggcttc tgataaaatt acgcgcgtgc
    11161 ttggagtagt caacggaact tccaacttca tggtgaccaa gatggtggaa gaaggctggt
    11221 cttacgatga tgctcttgcg gaagcacaac gtctaggatt tgcagaaagc gatccgacga
    11281 atgacgtaga tgggattgat gcagcctaca agatggttat tttgagccaa tttgcctttg
    11341 gcatgaagat tgcctttgat gatgtagccc acaagggaat ccgcaatatc acaccagaag
    11401 acgtagctgt agctcaagag cttggttacg tagtgaaatt ggttggttct attgaggaaa
    11461 cttcttcagg tattgctgca gaagtgactc caaccttcct acctaaagcg cacccacttg
    11521 ctagtgtgaa tggcgtaatg aacgctgtct ttgtagaatc tatcggtatt ggtgagtcta
    11581 tgtactacgg accaggtgcg ggtcaaaaac caactgcaac aagtgttgta gctgatattg
    11641 tccgtatcgt tcgtcgtttg aatgatggta ccattggcaa agacttcaac gaatatagcc
    11701 gtgacttggt cttggcaaat cctgaagatg tcaaagcaaa ctactatttc tcaatcttgg
    11761 ctacagactc aaaaggtcag gtcttgaagt tggctgaaat cttcaatgct caagatattt
    11821 cctttaagca aatccttcaa gatggcaaag agggtgacaa ggcgcgtgtc gttatcatca
    11881 cacacaagat taataaagcc cagcttgaaa atgtctcagc tgaattgaag aaggtttcag
    11941 aattcgacct cttgaatacc ttcaaggtgc taggagaata agatgaagat tattgtacct
    12001 gcaaccagtg ccaatatcgg gccaggtttt gattcggtcg gtgtagctgt aaccaagtat
    12061 cttcaaattg aggtctgcga agaacgagat gagtggttga ttgaacacca gattggcaaa
    12121 tggattccac atgatgagcg taatctcttg ctcaaaatcg ctttgcaaat tgtaccagac
    12181 ttgcaaccaa gacgcttgaa aatgaccagt gatgtccctt tggcgcgcgg tttgggttct
    12241 tccagctcgg ttatcgttgc tgggattgaa ctagccaacc aactgggtca actcaactta
    12301 tcagaccatg aaaaattgca gttagcgacc aagattgaag ggcatcctga caatgtggct
    12361 ccagccattt atggtaatct cgttattgca agttctgttg aagggcaagt ctctgctatc
    12421 gtagcagact ttccagagtg tgattttcta gcttacattc caaactatga attacgtact
    12481 cgcgacagcc gtagtgtctt gcctaaaaaa ttgtcttata aggaagctgt tgctgcaagt
    12541 tctatcgcca atgtagcggt tgctgccttg ttggcaggag acatggtgac cgctgggcaa
    12601 gcaatcgagg gagacctctt ccatgagcgc tatcgtcagg acttggtaag agaatttgcg
    12661 atgattaagc aagtgaccaa agaaaatgga gcctatgcaa cctacctttc tggtgctggg
    12721 ccgacagtta tggttctggc ttctcatgac aagatgccaa caattaaggc agaattggaa
    12781 aagcaacctt tcaaaggaaa actgcatgac ttgagagttg atacccaagg tgtccgtgta
    12841 gaagcaaaat aaagaataga agataggatg gggaaactct tgaccagagg gtttcatatc
    12901 ctttttgtga aaagaagttt atactcaatg aaaatcaaag agcaaactag gaagttagcc
    12961 gcaggctgct caaaacagtg ttttgaggtt gtggatagaa ctgacgaagt cagctcaaga
    13021 cactgttttg aggttgcaga tagaactgac gaaatcagta acatacctac ggtaaggtga
    13081 cgctgacgtg gtttgaagag attttcgaag agtattagtt aaaaacgtga taaaggagaa
    13141 ataaagatgg cagaaattta tctagcaggt ggttgttttt ggggcctaga ggaatatttt
    13201 tcacgcattt ctggagtgct agaaaccagt gttggctacg ctaatggtca agtcgaaacg
    13261 accaattacc agttgctcaa ggaaacagac catgcagaaa cggtccaagt gatttacgat
    13321 gagaaggaag tgtcactcag agagatttta ctttattatt tccgagttat cgatcctcta
    13381 tctatcaatc aacaagggaa tgaccgtggt cgccaatatc gaactgggat ttattatcag
    13441 gatgaagcag atttgccagc tatctacaca gtggtgcagg agcaggaacg catgctgggt
    13501 cgaaagattg cagtagaagt ggagcaatta cgccactaca ttctggctga agactaccac
    13561 caagactatc tcaggaagaa tccttcaggt tactgtcata tcgatgtgac cgatgctgat
    13621 aagccattga ttgatgcagc aaactatgaa aagcctagtc aagaggtgtt gaaggccagt
    13681 ctatctgaag agtcttatcg tgtcacacaa gaagctgcta cagaggctcc atttaccaat
    13741 gcctatgacc aaacctttga agaggggatt tatgtagata ttacgacagg tgagccactc
    13801 ttttttgcca aggataagtt tgcttcaggt tgtggttggc caagttttag ccgtccgatt
    13861 tccaaagagt tgattcatta ttacaaggat ctgagccatg gaatggagcg aattgaagtt
    13921 cgttctcgtt caggcagcgc tcacttgggt catgttttca cagatggacc gcgggagtta
    13981 ggcggcctcc gttactgtat caattctgct tctttacgct ttgtggccaa ggatgagatg
    14041 gaaaaagcag gatatggcta tctattgcct tacttaaaca aataaaacag agagggtggg
    14101 gtttcccact ttcttcattt ctagaatatg aatagaaggg atttatgaaa cacctattat
    14161 cttacttcaa accctacatc aaggaatcaa ttttagcccc cttgttcaag ctgttagaag
    14221 ctgtttttga gctcttggtt cccatggtga ttgctgggat tgttgaccaa tctttacctc
    14281 agggagatca aggtcatctc tggatgcaga ttggtctgct ccttatcttt gcagtaattg
    14341 gcgttttagt ggccttgata gctcaatttt actcagcaaa ggcagcagta ggttttgcta
    14401 aggaattgac aaacgatctt tatcgtcata ttctttcctt gcccaaggat agcagaaacc
    14461 gtctgacaac ttctagtttg gtcactcgct tgacttcgga tacctaccag attcagactg
    14521 gtatcaatca attcctgcgt ctctttttac gagcgcccat tattgttttt ggtgccattt
    14581 ttatggctta tcgaatctca gctgagttga ctttctggtt cttagtcatg gttgccattt
    14641 tgaccattgt cattgtaggg ttatctcgat tggtcaatcc tctctacagt agtctcagaa
    14701 agaaaacgga ccaactggtt caggaaacgc gccagcaatt gcaagggatg cgggttattc
    14761 gtgcttttgg tcaagaaaaa cgagagttac agatttttca aacccttaac caagtttatg
    14821 ctagattaca agaaaagaca ggtttcttgt ctagtttatt aacacctctg acctatctga
    14881 ttgtcaatgg aactcttctc gttattatct ggcaaggcta tatttcaatt caaggaggag
    14941 tgctcagtca aggtgctctc attgctctta tcaattacct cttacagatt ttggtggaat
    15001 tggtcaagct agccatgttg ataaattccc tcaaccagtc ctatatttca gccaagagaa
    15061 tcgaggaggt ctttgcggaa tctcccgaaa acatccattc agaattagaa caaaagcaag
    15121 ttaccagtgg tcgggtttta caagtccaag aattggcttt tacctatcct gatgcggccc
    15181 agccttctct gagagacatt tcctttgata tgactcaagg acaaatcctt ggtatcattg
    15241 gggggactgg ttctggtaaa tcaagcttgg tgcaactctt acttggactt tatccagtag
    15301 acaaggggaa cattgacctt tatcaaaatg gacgtagtcc tcttaatttg gagcagtggc
    15361 ggtcttggat tgcctatgta cctcaaaagg tcgaactctt taaaggaacc attcgttcca
    15421 acttgactct aggtttcaat caagaagtat ctgaccagga actctggcag gccttggaga
    15481 ttgcgcaagc taaggatttt gtcagtgaaa aggaaggact cttggatgct ctagttgagg
    15541 caggggggcg aaatttctca ggtggacaaa aacaaagatt gtctatcgcc cgagcagtct
    15601 tgcgccaagc tccgtttctc atcctagatg atgcgacctc agcactggac accattacag
    15661 agtccaagct gttgaaagct attagagaaa attttccaaa catgagctta attttgatct
    15721 ctcaacgaac ctcgacttta cagatggcgg accagattct cctcttggaa aaaggtgagt
    15781 tgctagctgt tggcaagcac gatgacttga tgaaatccag tcaagtctat cgtgaaatca
    15841 atgcatccca acatggaaag gaggactaga atgaaacgac aaactgtaaa ccagacgctc
    15901 aaacgtttag ccgtagattt agcaaaccat cccttcctcc ttttcctagc ctttctagga
    15961 actattgccc aagttggctt atcaatttac ctacctattc tgattgggca ggtcattgac
    16021 caagtcctag tggctggttc atcaccagtt ttttggcaga tttttctcca gatgctcttg
    16081 gtggtaatag gaaatactct ggtacaatgg gccaatcctc tcctctataa tcgtctaatc
    16141 ttctcttata ccagagattt acgggggcga atcatccata aactccatcg gttaccgatt
    16201 gcctttgtag ataggcaagg tagtggagag atggttagtc gtgtaaccac ggacatcgaa
    16261 cagttggcag ctggcttgac catgattttt aaccaatttt tcattggtgt tttgatgatt
    16321 ttggttagta ttctagccat gctccaaatt catctcctca tgactctctt agtcttgcta
    16381 ttgacgccac tgtccatggt gatttcacgc tttattgcca agagatccta tcatctcttc
    16441 cagaagcaaa cagagacgag ggggattcag actcagttga ttgaagaatc gcttagccag
    16501 cagactataa tccagtcctt caatgctcaa acagaattta tccaaagatt gcgtgaggct
    16561 catgacaact actcaggcta ttctcagtca gccatctttt attcttcaac ggtcaatcct
    16621 tcgactcgct ttgtaaatgc actcatttat gcccttttag ctggagtagg ggcttatcgt
    16681 atcatgatgg gttcaacctt gaccgtcggt cgtttagtga cttttttgaa ctatgttcag
    16741 caatacacca agccctttaa tgatatttct tcagtgctag ctgagttgca aagtgctctg
    16801 gcttgcgtag agcgtatcta tggagtctta gatagccctg aagtggctga aacaggtaag
    16861 gaagtcttga ccagtgacca agttaaggga gctatttcct ttaaacatgt ctcttttggc
    16921 taccatcctg aaaaaatttt gattaaggac ttgtctatcg atattccagc tggtagtaag
    16981 gtagccatcg ttggtccgac aggtgctgga aaatcaactc ttatcaatct ccttatgcgt
    17041 ttttatccca ttagctcggg agatatcttg ctggatgggc aatccattta tgattataca
    17101 cgagcatcat tgagacagca gtttggtatg gtgcttcaag aaacctggct cacacaaggg
    17161 accattcatg ataatattgc ctttggcaat cctgaagcca gtcgagagca agtaattgct
    17221 gctgccaaag cagctaatgc agactttttc atccaacagt tgccacaggg atacgatacc
    17281 aagttggaaa atgctggaga atctctctct gtcggccaag ctcagctctt gaccatagcc
    17341 cgagtctttc tggctattcc aaagattctt atcttagacg aggcaacttc ttccattgat
    17401 acacggacag aagtgctggt acaggatacc tttgcaaaac tcatgaaggg ccgcacaagc
    17461 ttcatcattg ctcaccgttt gtcaaccatt caggatgcgg atttaattct tgtcttagta
    17521 gatggtgata ttgttgaata tggtaaccat caagaactca tggatagaaa gggtaagtat
    17581 taccaaatgc aaaaagctgc ggcttttagt tctgaataag ccattctctt ttgaaagttt
    17641 atggacgaaa aaagttgcct tcgagtgact tttttgttac aatagctaga aaaattgttc
    17701 actgtaatac tcaatgaaaa tcaaagagca aactaggaag ctagccgtag gttgctcaaa
    17761 gcacagcttt gaggttgtag ataagactga cgaagtcagt tcaaaacact gttttgaggt
    17821 tgcagataga actgacgaag tcagtaacca cacctacggc aaagtgaatc tgaagtggtt
    17881 tgaagagagt acaacttgtc ttttagaaaa ggagcctaca atgaaagtct ttcagcatgt
    17941 aaatatcgtg acttgtgatc aagatttcca tgtttatctt gatggaatct tagcagtcaa
    18001 ggattctcaa atcgtctatg tcggtcaaga taagccagcg tttttagagc aagctgagca
    18061 gattatagac tatcagggag cttggattat gcctggtttg gtcaattgtc acacccattc
    18121 tgcaatgaca ggtctgagag ggatccgaga tgacagcaat ctccatgaat ggctcaatga
    18181 ctatatctgg ccagcagaat ctgagtttac tcccgacatg actaccaatg cggtcaaaga
    18241 agccctgaca gagatgctcc agtcaggaac aacaaccttt aacgatatgt ataatcccaa
    18301 tggtgtggat attcagcaaa tttatcaggt ggtgaaaact tccaagatgc gttgttattt
    18361 ttctccgact ctcttttctt cagagacaga aacaactgct gagactataa gcagaactcg
    18421 atccatcata gacgaaatct taaaatataa aaatccaaat ttcaaggtta tggtagcacc
    18481 tcattctccg tatagctgca gtagagactt gctggaagcg agtttggaaa tggcaaaaga
    18541 gctaaatatt ccgctccatg tccatgtggc ggagaccaag gaggagtcag gaattatcct
    18601 caaacgatac ggcaaacgcc cccttgcttt tcttgaagaa ctgggttatt tagatcatcc
    18661 gtccgtattt gctcacgggg tcgaattaaa cgagagagaa attgaacgct tggcatcttc
    18721 tcaagtggct atcgcccaca atcctatcag taacctcaaa ctggcatcag gaattgctcc
    18781 aattatccag ctccaaaaag cgggagtagc agtcggaatt gcgactgact cggttgcttc
    18841 caataacaat ctagatatgt ttgaggaagg aaggactgca gctcttcttc agaagatgaa
    18901 aagtggggat gccagccagt ttccaatcga aacagctctc aaggtactga caatcgaagg
    18961 ggctaaggcc cttggaatgg aaaatcagat aggaagtctg gaagtcggca agcaagcaga
    19021 ttttctggtc attcaaccac aagggaaaat tcatctccaa cctcaggaaa atatgctgtc
    19081 tcacctggtt tatgcagtta aatctagtga tgtagatgat gtttatatcg ccggagaaca
    19141 ggttgttaag caaggtcaag tcctgacagt agaactttaa aagaaaaatc acgaaaaatt
    19201 ttaaaaaaag tttgcaaaaa tcttgcattc tttttttgac tatgctatac ttatatacgg
    19261 tttaaaaaaa ctgcctaaga cagtagggga gctcgactca taaatatcct accgaggaca
    19321 agacgtatca tgtaaaaaga agcgtattgt actttcgtgt ctaggtttgg gcgcgttttt
    19381 ctttttgaaa aattccccaa gcaaaataat tacggaggtg aacacactaa tgagtgaagc
    19441 aattattgct aaaaaagcgg aactagttga cgtagtagct gaaaaaatga aagctgctgc
    19501 atctatcgtc gttgtagacg ctcgtagttt gacagttgag caagatacag ttcttcgtcg
    19561 tgagcttcgt ggaagcgaag ttgagtataa agttattaaa aactcaatct tgcgtcgtgc
    19621 agctgaaaaa gctggtcttg aagatcttgc atctgtattt gttggaccat ctgcagtagc
    19681 attttctaat gaagatgtta tcgcaccagc gaaaatcttg aacgactttt ctaaaaacgc
    19741 tgaagcactt gaaattaaag gtggtgcaat cgaaggcgct gtcgcatcta aagaagagat
    19801 tcttgcactt gcaactcttc caaaccgcga aggacttctt tctatgctcc tttctgtact
    19861 tcaagcgcca gtgcgcaacg ttgctcttgc agtcaaagcg gttgcagaaa gcaaagaaga
    19921 cgcggcttaa tcttaagcta catagcgtag cctagctacg aaaaaaacta ttataaaatt
    19981 taaaacttat ttggaggaaa taacaatggc attgaacatt gaaaacatta ttgctgaaat
    20041 taaagaagct tcaatccttg aattgaacga ccttgtaaaa gctatcgaag aagaatttgg
    20101 tgtaactgca gctgctcctg tagctgttgc tgcagctgat gcaactgatg ctggtgctgc
    20161 taaagattca ttcgacgttg aattgacatc tgcaggcgac aaaaaagttg gtgttatcaa
    20221 agttgtacgt gaaatcactg gtcttggtct taaagaagct aaagaacttg ttgacggtgc
    20281 accagcactt gttaaagaag gcgttgcaac tgcagaagct gaagaaatca aagctaaatt
    20341 ggaagaagct ggagcttcag ttactcttaa ataagaggca tataccaatt agaaatcgga
    20401 atactatagt atcagccttt tagaatcgtg aacacatttt agaaactgat aaattaattt
    20461 agtttcctac caaaaaccct accaaaaatt aatttggcag ggtttttctt tttaacaaat
    20521 ttatcgtgga gaacaattga atattgttct ccttttttta ttttcaggag gaaaaatgac
    20581 aaaagaatta caatcatcac gccatattgt catttcattt ttagtacgtg aaatgggaat
    20641 tgacattgtt gaggccatct ctcttatggc tgaattagaa aaaagtggct tggttcgctt
    20701 ggaatcaagt ggagatttaa tactcaaaga acttggagga gcgctatgaa acgaattacc
    20761 gcaaatcaat accaaacttc agaacggtat tataaattac ctaaaattct ttttgaagat
    20821 gagaaatata tggatatgaa actagaagta aaggtggctt attctatttt aaaagatcgt
    20881 ttagaattat ctctcagtcg tggttggata gatgaagaag gagcggttta tttagtattt
    20941 tctaattcta aactgatgaa gctattaggt tgttcgaagt caaaattact gtccatcaaa
    21001 aaaactctta aagaatatga cttaattgat gaagttcaac agtcttcaag tgagaagggg
    21061 agactagcta ataagattta tttaggggaa ttatcttcta ccccagtagg taattcaaac
    21121 aggcctagtg ttaaaaaaag actagggcag gatgaaaatg atacggcccc cgtctcacat
    21181 ttagccccta gtgagactga agttagtgag actaaatata gtgagactga ttctttattt
    21241 attgaggatg aggaggagag gaatactcaa cctatcttga aaagaaaagt agaaaaggtc
    21301 acaaaatatg atcgagatta tatttgggga ttggtacaag atcaatttag acgagagggg
    21361 ttttctgaaa cagccagtga aattgctatg actgattttg agagaatcta tcagtatgct
    21421 cttgacaatg ttcgctttgt tagacgtgcg gaagtacttg ctgaatttgt gtttaatggc
    21481 ttgtattctg tttggaacaa ccgtgttaga aaaggaggtg gttaaatgtc gccaatcgag
    21541 tggatattag ttatgctcat tgtcatttca agtggagtga cagttctgac aatgatagtc
    21601 gataagaaag gggtgataaa gaattgagat ttattgattt attttcaggt atcggtggct
    21661 ttcgacttgg aatggaaagt gttggacacg agtgtattgg attttgtgag atcgataaat
    21721 ttgctagaga atcttataag tccatttttc aaacggaagg agaaatagaa tttcatgaca
    21781 tacgagatgt ttcagatgac gaatttaaaa aacttagagg gaaagtcgat gtcatctgtg
    21841 ggggattccc ttgtcaagca ttttcaatcg caggaagacg attgggattt gaagatacta
    21901 gaggaacttt gttctttgaa attgctcggg cggccaaaca aatccaacca cgttttcttt
    21961 ttcttgaaaa tgttaaaggc ctactcaatc acgataaggg acggacgttc accacaatcc
    22021 ttaccacact tgatgagttg gggtttgatg ttgagtggca ggtgcttaac agtaaggatt
    22081 ttggcgttcc ccaaaacaga gagagggtgt ttattatcgg acattctaga aagaaaggta
    22141 cccgactcct atttcctttc agacgagaag gtcaagcaac taactctgag actttgaaag
    22201 cactaggaaa tttgaatcca tcaaaaagtg gaatgagtgg taaagtctat tattcagaag
    22261 gtcttgcgcc aaccttagtt cgtggaaaag gagaaggatt taaagttgcg attccttgta
    22321 tgacaccaga cagattagaa aagagacaaa atggtagacg tttcaaggat aatcaagagc
    22381 caatgtttac tttaaatact caggatcgcc atggtattgt cgttgttgga gatttaccaa
    22441 ctagctttaa ggaaactggt cgcgtctatg gaagtgaggg gctatctcca acactgacta
    22501 cgatgcaagg tggagataaa atccccaaaa tactgattcc agaaccaatc caatttctaa
    22561 aagtccgaga ggcaacgaaa aaaggatatg ctcaagcaga gattggggat tcaatcaatt
    22621 tagaaagacc aagttctcag tatcgtcgtg gtagagttgg aaaaggtata gcgaatacgt
    22681 taacaactag tgggcaaatg ggagtagtag tggctagcta tgaaggagaa gataaacaag
    22741 tttaccaagt agctggtatc ttaattgatg ggcaatttta ccgtttgagg atacgacgaa
    22801 tcactcctaa agagtgtttt agactgcagg gctttcctga ttgggctttt gaagctgcta
    22861 gaaaagtctc tagtaatagt cagctctata aacaagctgg taatagtgta accgttcctg
    22921 tgattgccgc aatcgcaaaa aaattaaaag aaatagagga aaaagatgaa agcattaaat
    22981 agagaatcaa tactagattg tgatgaatta gaaacagaat tacatgacgc agaaatcaaa
    23041 cagctggatg aacaaatatt tttaatgcct aattatccat gtgagtttga ggtgacattt
    23101 ttagatgatt accataaaaa acataattac ccactatttt atgaatccta tcttcaaaac
    23161 attatggaat tccttgaaag tcaggatata aagaacggag ctgatgcctt tgtagatgat
    23221 aatcagaatc tagtttttgt tttatatgga caaggctatc gagccgaggg aaaagaggga
    23281 atacttacaa cccaagtaac tgtaaaagct tatgatgaag acaagcaacc gattaacttc
    23341 gcaaatttat tagattcctt aatcgtatca gaatatcaaa tggaaccgaa tctttgggag
    23401 gtttcccatg attgatctct atctaagtaa aaataaccat agaaatcaac ttcttttgga
    23461 tttcttccaa aactatggta tcgaggtatc ttgtcattca gtttctgaaa tgacaaagga
    23521 caaattaatt gagatgatga gctattcttc agattgtttc gagtttttat ctcccaattt
    23581 attacgattt aagaaccgtg acaatttaag attaacggat tttattgaaa tgatcttaaa
    23641 aaatcctgaa ctaaccatca gacttcctct tgcggtttcg aataaaagag tttatccaaa
    23701 tctgaatctg gaggaggcta gagctttatt gccaagagat acgaaacaat tgatttacat
    23761 ggcacaaaca cattatttat ctaactaaag gagaagcaat atggctgaac gattttggga
    23821 gaacttgtcc attattttgg ctgaaagaaa tattagctgg attgagttaa ccagaaaaat
    23881 gtttgcggga gagtttcact atccaagtga attgaaccgt ttgtatcaaa agatacgcca
    23941 ctacaagatg gaacaacgaa tgcctcaaag tccatgggta gaaaggattg tgcaggtatt
    24001 agatttagat tatgaagatt tatttcggag gtaactatga aaagaatcat tccagtttat
    24061 atattccaac aagtaaatgt cctattggta tctctatact tactgaaatt gctttgtatc
    24121 ggtgagttaa ctatactaca gattctctat ggtgcgtcac tcatttcttt tttatggatg
    24181 tatggccaac gcaaacaagc tcataaggtc aatatgaaat ctaggatgaa atggcttggt
    24241 attggattca ttagcctact gattataagt ctatgtttta gcctaatcca tgctcaagga
    24301 accacgaatc aagcaaactt aattggactt caacatcaag ttccttggtt ttcattttta
    24361 ttgttcttaa tcaatgcgag tatggttgaa gaatttctgt atcgagaaat tttatggaac
    24421 ttggttagaa aattagatat tcgagttgct ttgacaagtg ttttatttgc cttagcacat
    24481 catccaggaa ccattctagc ttggtgttta tatgtttcac ttgggatgtt tttagggctt
    24541 gtacgctaca aatcggactt atggggcagt atggggctac atttggtgtg gaacctatca
    24601 gtctatgtct tatttttgct ttaataatag ctgttctgtc ttacgtatgg attaattttg
    24661 aaataaaaat agcataaaaa tctagttatc cgcataaaaa ctggacttat cacactttat
    24721 caaggtcaaa accactcaat ttactactaa tttactactt atgaatgagc tttgatacga
    24781 cgatttatcc ttgaaaagtg aagatataaa gatacttcca ataaaatttg aatatttaat
    24841 aggtagacac ttcaaaaaat gaggtgtcta tttttttacc cgattttgaa aggaagtgaa
    24901 cttatgaaaa caaaaaatca agaatcaaaa ggtcgttccc cactctttaa gaccatcaaa
    24961 cattcattca gccaataaaa aagaaaggat aggtaaaaat atggaactta aatttgtgat
    25021 tcccaacatg gaaaaaacat tcggcaattt agaatttgct ggcgaggata aagtcgttca
    25081 gcgaagaatc aacggacggc taactgtctt atcaagaagc tataatctct attctgatgt
    25141 tcaaagagca gatgatattg tggtggtgct tcctgctgaa gctggcgaaa aacatttcgg
    25201 ctttgaggaa cgtgtgaagt tagtcaatcc acgtattacc gcagagggct acaaaatcgg
    25261 cactcgtggt tttacaaatt accttttaca tgctgacgac atgataaaag aataaagaaa
    25321 gagaggaaaa atgatgagat tagcaaatgg cattgtatta gataaagaca cgacttttgg
    25381 agaattgaaa ttctctgctc tacgtcgtga agtgagaatc caaaatgaag acgggtcggt
    25441 ttcagatgaa atcaaggaac gtacctatga cttaaaatcc aaaggacaag gacgcatgat
    25501 tcaagtaagt attcctgcca gcgtgccttt gaaagagttt gattataacg cacgggtgga
    25561 acttatcaat cccattgcgg acaccgttgc tactgccacc tatcaaggag cagatgttga
    25621 ctggtatatc aaggcagacg atattgtgct gacaaaggat tctagttcat tcaaagctca
    25681 accacaagca aagaaagaac cgacacaaga caaatagtcg ctaggtagaa aggagacttt
    25741 ttcgcatgaa acagcgtggt aaaaggattc gcccatctgg taaagattta gtctttcatt
    25801 ttacgatagc gtcactcctg cctgttttcc tgctggttgt cggactgttt catgtgaaga
    25861 caatccagca gatcaactgg caggatttta acctatcaca agcagataag attgacattc
    25921 cctatttaat tatcagtttc agtgtcgcaa ttcttatctg cttgctggta gcgtttgtat
    25981 tcaaacgggt tcgctatgat acggttaaac aactttacca ccgtcaaaaa ctggcaaaga
    26041 tgatacttga aaacaagtgg tatgaatctg aacaggtcaa aacagagggt ttctttaaag
    26101 atagtgctgg tcgtacaaaa aagataacct acttccctaa aatgtattat cgacttaaaa
    26161 atggcttgat acagatacgg gtggaaatca cgctgggaaa atatcaagac caactcttac
    26221 acttggaaaa gaaattagag agtggcttgt actgtgagct gacggataaa gagttaaagg
    26281 attcctatgt ggaatatact ttgctctatg acaccatagc cagtcgtatt tctattgatg
    26341 aagtagaagc taaagatggt aaacttcgct taatgaaaaa cgtatggtgg gaatatgata
    26401 agctccctca tatgttgatt gctggtggta caggtggcgg taaaacttac tttatactga
    26461 cactgattga agccttgctt catacagatt caaaactgta tattcttgac ccgaaaaatg
    26521 ctgaccttgc ggacttaggt tctgtgatgg caaatgtcta ctatagaaaa gaagacttgc
    26581 tttcttgcat tgaaacattc tatgaagaaa tgatgaaacg tagtgaggaa atgaagcaga
    26641 tgaagaacta taagactggc aaaaattatg cttacttagg tctcccggca cacttcttaa
    26701 tctttgatga atacgtcgct ttcatggaaa tgctgggaac aaaagaaaac accgcagtta
    26761 tgaataagct gaaacagatt gtcatgttag gtcgtcaagc tggcttcttt ctaatactgg
    26821 cttgtcaacg tccagacgca aaatatttag gcgacggaat ccgtgatcag tttaatttca
    26881 gagtggcttt aggtcgtatg tctgaaatgg gctatggcat gatgtttggc agtgacgtac
    26941 aaaaggattt cttcttaaag cgaatcaaag gtcgtggcta tgttgatgta ggaacaagtg
    27001 tcatatcaga gttttatact ccccttgtac caaaaggata tgatttcttg gaggaaatta
    27061 aaaagttatc caacagcaga cagtccacgc aggcgacgtg cgaagcggaa gtcgcaggtg
    27121 tggactgatc ttgctggctg gtgtggcaat agccacgcca gcacttaacc ccccgtatct
    27181 aacagggggg tacaaatcga caggaaacag tcaaaaaaac attagaaaat cctttggtta
    27241 caagggattt acaaaatttc agcgtatgtc aaatgggctt taaaagttga catacgcctt
    27301 tttgattgga gggattttta ctgaatgaac aaacttggtt acagcattta aaagaaaaac
    27361 gcttggctta tggactatct caaaaccgtt tagctgttgc gactggtatt acaaggcagt
    27421 atctaagcga tattgaaaca ggaaaagtca agccatcaga ggatttacag cagtcccttt
    27481 gggaagctct ggaacgcttc aatcccgacg ctccccttga aatgctgttt gattatgtaa
    27541 ggattcgctt tccgacaaca gacgtacagc aggtggtcga aaacatctta caactgaaac
    27601 tgtcctattt tcttcatgag gactatggtt tctattctta ttcagagcat tatgctttag
    27661 gcgacatatt cgtcctttgc tcccatgaac tggacaaagg agttctggtg gaattgaaag
    27721 gtcgtgggtg cagacaattt gaaagctatc ttctggcaca acaaagaagc tggtatgagt
    27781 tctttatgga cgttttggtg gctggcggtg tgatgaaacg ccttgacctt gccattaacg
    27841 ataagacagg gattttgaat atccctgtac tcactgaaaa gtgccaacag gaagaatgta
    27901 tctccgtctt ccgcagtttt aaaagctatc gcagtggcga actggtacgc aaagaggaaa
    27961 aggaatgtat gggaaacacc ctctatatcg gttcattaca aagtgaagtt tatttctgta
    28021 tctatgaaaa ggactacgag cagtacaaga aaaatgatat tcccattgaa gacgcagaag
    28081 taaaaaaccg ttttgagatt cgattgaaaa atgagcgtgc ctattatgca gtccgtgatt
    28141 tactcgtcta tgacaatcca gagcataccg cctttaaaat tatcaatcgg tatatccgtt
    28201 ttgtagataa agacgattcc aaacctcgtt ctgattggaa actgaatgaa gaatgggctt
    28261 ggtttattgg gaacaatcgt gaacgattaa aactaaccac aaaaccagag ccttactcct
    28321 tccaaaggac gctgaactgg ctatctcatc aagttgcccc gaccttaaag gttgcgatta
    28381 aacttgatga aatcaaccag acgcaggttg taaaagacat tctcgaccat gcgaaactga
    28441 cagaccgaca caagcagatt ttgaagcaac agtcagtaaa agaacaggac gtgataacaa
    28501 caaaaaaata actcaaatac aaattcattg aatatagaga ggagaacatt tttatgaatt
    28561 ttggacaaaa cctttataac tggtttctat caaacgctca atcactggtg cttttagcaa
    28621 tcgttgtgat tggcttgtat cttggcttca agcgtgagtt tagcaaactg attggctttt
    28681 taattattgc gattattgcg gttggcttag tcttcaacgc tgctggagta aaagacattt
    28741 tactagagct attcaatcgc attattggtg cttaaataaa accgttcttt tgtggaatat
    28801 aagtggtttt cttatgttcc gcaaaggaat ggtacaccaa acgaagtgcg gtagggattt
    28861 ttgaatctct acaaagaaag gacgtgaata tatggacgat atgcaagtct atattgcgaa
    28921 tttaggcaaa tacaatgagg gcgaattggt cggtgcgtgg tttacctttc ccattgactt
    28981 tgaggaagtc aaagagaaaa tcggcttgaa tgatgaatat gaggaatacg ccattcatga
    29041 ctacgagtta ccctttacgg ttgacgaata cacttccatt ggcgaactca atcgactatg
    29101 ggaaatggta tcggaattac ccgaagaatt acaatcggag ctatctgctc tgctcactca
    29161 tttttcaagc attgaagaac taagcgaaca tcaagaggat attatcattc attccgattg
    29221 tgatgatatg tatgacgtgg cacgctacta cattgaagaa acgggtgctt taggcgaagt
    29281 accagctagt cttcaaaact atattgatta tcaagcctat ggtcgggatt tagacctttc
    29341 aggaacgttt atctcaacca atcatgggat ttttgaaatc gtctattaaa tctgtcggta
    29401 cattactact ggcagatttt ctattttacg gggtggctca atcagctacc cctatttttt
    29461 atgaaaggat tgattacatg aagaaaatac gaagctatac cagtatctgg tctgtggaaa
    29521 aggtactgta ttctatcaat gattttagac ttccgtttcc cataaccttt acgcaaatga
    29581 catggtttgt cgtgtcactc tttgcagtga tgatacttgg caacttgccc cctctttcca
    29641 tgatagaggg agcatttctc aaatactttg ggattcctgt ggctttcaca tggtttatgt
    29701 ctacaaaaac ttttgatggt aaaaagcctt atggattttt gaagtctgtc attgcttatg
    29761 cactgcgacc aaagctgacc tatgcaggaa aaaaagtaac gcttggcaga aaccagccac
    29821 aagaagccat tacagcagtt aggagtgaat tttatggcat atccaattaa atacattgaa
    29881 aacaatctcg tctggaataa agacggggaa tgttatgctt actatgagct tgttccttac
    29941 aattactcat ttctcagtcc agaacagaaa atacaagtgc atgattcttt cagacagctt
    30001 atcgcacaaa atcgtgatgg caaaattcat gctttacaaa tcagtacaga atccagcata
    30061 cgttctgcac aagagcgttc caaaaatgaa gtcactggca agctcaaagc ggttgcctat
    30121 gacaaaatcg accaacagac agacgcttta atatccatga ttggcgaaaa tcaagtgaac
    30181 taccgtttct ttatcggctt taagttgctt ctcaacgatc aggagttttc tatgaaaagt
    30241 cttaccgttg aagcaaaaaa tgctttgtct gattttgtct atgatgtgaa ccataagctg
    30301 atgggcgatt ttgttagtat gagtaatgat gaaatcctgc gatttcagaa gatggaaaag
    30361 ctcttagaaa ataaaatctc tcgtcgtttc aaaatccgca ggttagataa ggacgacttc
    30421 ggctatctga ttgaacacct ttacggacag acaggcactg cctatgaaga gtatgagtac
    30481 catctatcaa agaaaaagct ggataatgaa acgctgatta aatactatga cttgattaag
    30541 cctactcgct gtttggtgga agaaaaacag cgatatttga aaatccagca ggaagatgaa
    30601 accgtctatg tagcttactt taccattaac agcattgtcg gagaactgga cttcccgtcc
    30661 tctgaaatct tctactacca gcaacagcaa tttacattcc cgattgatac gtcaatgaat
    30721 gtggaaattg tagcgaatcg taaagcccta tctactgtcc gcaataaaaa gaaagaactg
    30781 aaagacttgg ataaccacgc ttggcaaagt gataatgaaa ccagctccaa tgtggcggaa
    30841 gctctggaaa gtgtgaatga gctggaaacc aatttagacc aaagcaagga atctatgtac
    30901 aagctgtctt atgtggtaag ggtatcagca aatgatcttg acgaactcaa acgtcgttgt
    30961 aatgaagtga aagattttta tgacgattta agcgtaaaac tggtacgacc atttggggat
    31021 atgctcggct tacatgaaga atttttacct gccagcaagc gttatatgaa tgattatatt
    31081 caatacgtga cctctgattt cctcgctggt ttaggttttg gtgctactca aatgctgggg
    31141 gaaaatgagg ggatttatgt tggctacagc ttagatactg gacgcaatgt ctatctgaaa
    31201 cctgctcttg ccagtcaagg ggttaagggt tcagtaacca atgcgttagc gtcggctttt
    31261 gttggttcgc tgggtggtgg taaatccttt gcgaataacc ttatcgtcta ttatgcggtg
    31321 ctttatgggg cacaagcagt gattgtagac ccaaaagcag aacgtggcag atggaaagaa
    31381 accttgccag agatttccca tgaaatcaat atcgtcactc tgacttctga tgagaaaaac
    31441 aaaggcttac ttgaccctta tgtgattatg aaaaatccca aagattctga atcactggct
    31501 attgatattc tgacattcct tacggggatt tcctctcgtg atggggaacg cttcccaatc
    31561 cttagaaaag ccattcgtgc agtaaccaat agtgaagtac gagggttgat gaaagtgatt
    31621 gaggaattac gggttgagaa tacgccacta agtaccagta tagccgacca tatcgaaagt
    31681 tttacagact atgactttgc acatttatta ttcagtaatg gttatgtgga gcagtctatc
    31741 agcttagaaa aacaactgaa cattatacag gttgcggact tggtacttcc cgacaaggaa
    31801 acttcctttg aggaatatac cactatggag cttttatccg ttgctatgct gattgtcatt
    31861 agtacctttg ctttagactt tatccataca gaccgaagca ttttcaagat tgtagattta
    31921 gacgaagcat ggagcttttt acaggtagca caaggaaaaa cactatctat gaagctggtt
    31981 cgggctggtc gtgctatgaa cgctggggta tatttcgtga cccaaaatac agacgacctc
    32041 ttagatgaaa aactgaaaaa taacctcggc ttaaaatttg catttcgttc cactgacctt
    32101 aacgagatta aaaagacctt agcctttttt ggtgtagacc cagaggacga aaacaatcag
    32161 aagcgattgc gtgatttgga aaacgggcaa tgccttatca gtgatttata tggtcgtgtc
    32221 ggtgtgatac agttccaccc tgtatttgaa gaactgctcc atgcctttga taccagacca
    32281 cctgtgcgaa aagaggtgta aatgtgaaac catcaatagt aaacagaata aaatcaaact
    32341 ggacgctgaa acgtctaggt aaagtggcaa tgacagtggc tttcacactt gtgattgcca
    32401 tttttctttt agccatgctg ggaacggtgg ttcaagctgc gggcttggta gatgatacgg
    32461 tcaatgtggc aaatgaatac agccgatacc cacttgaaaa ctatcaactg gatttttatg
    32521 tggataatag ctggggctgg cttccgtgga actggtcgga cgggattgga aaacaggtca
    32581 tgtatggact atatgccatt accaatttta tttggacaat cagtttgtat gtttccaatg
    32641 cgacaggtta cttagtacag gaagcctatt ccttagactt catttccgct acagcagatt
    32701 ccattggtaa gaatatgcag accttagctg gtgtgagtgc aaacggattt tcaacagagg
    32761 gtttctatgt tggattcctc ttactcttga ttttggttct tggggtttat gttgcctata
    32821 cgggactgat aaagagagaa accacaaagg caattcatgc cattatgaat tttgtgctgg
    32881 tgtttatcct atcggcttcc tttattgcct acgctcccga ctacattaaa aaaatcaatg
    32941 acttttcatc agacatcagt aatgccagtt tatcacttgg cacgaagatt gtcatgcccc
    33001 attccgatag tcaaggcaag gacagcgtgg acttaatcag agatagcctg ttttccatac
    33061 aggttcagca accgtggcta ctgcttcaat acaacagttc agacattgaa agtatcggta
    33121 ttgaccgtgt ggaaagcctg ctctccacca gcccagattc caacaatggc gaagacagag
    33181 aaaaaattgt tgcggaagaa attgaagaca gaagcaatac caatctaacc attacaaaga
    33241 ccattaaccg tttaggtaca gtcttcttcc tatttgtctt caatattggg atttccatat
    33301 ttgtattcct attaacagga atcatgattt tctcgcaggt actttttatc atctatgcta
    33361 tgtttctgcc tgtgagcttt attttaagca tgattccatc atttgatggt atgtcaaaac
    33421 gagccataac aaagctcttt aataccattt tgacacgagc tggaatcaca ttgattatta
    33481 cgacagcatt tagtatttca accatgctct ataccttatc ggctggttat ccgttctttt
    33541 tgattgcttt tctacagatt gtgacctttg caggaatcta cttcaagctg ggcgatttaa
    33601 tgagtatgtt ttctctacag agtaacgatt ctcaaagtgt gggaagtcgt gtgatgagaa
    33661 aacctcgtat gcttatgcac gctcacatgc accgtctaca gcggaaactt ggacgttcca
    33721 tgactactct aggggctggg tctgccattg ttacaggtaa aaaaggacag tcgggttcgg
    33781 ggagttctgc aaggacacaa gcagatcact cccgaccaga cggaaaggaa aaatcaacac
    33841 ttggaaaacg tatcggtcaa accatcggta cagtagctga taccaaagac agaatggtag
    33901 acactgctag tggtttgaaa gaacaggtta aagatttgcc gaccaatgca agatatgcag
    33961 tatatcaagg aaaatccaaa gtaaaagaga atgtccgtga tttaaccagt agtatttctc
    34021 aaaccaaagc ggacagagcc agtggacgca aggaacagca ggaacaaagg cgaaaaacca
    34081 ttgcgaagcg tcgctctgaa atggaacagg tcaaacagaa aaaacagcct gcttcttctg
    34141 ttcatgaaag accgactaca agacaagaac aatatcatga tgaacagacc tcaaaacagt
    34201 ctaatattca gacttcatat aaggaatctc aacaagccaa acaagagcgt ccagcagtta
    34261 agtccgattt ttcaagtcca aaagtggaac gccaaggcaa taccgttcaa gaaaaaaccg
    34321 ttcaaaagcc agcaacttca accactacag cagatagaac ttcacaacgt ccaatcacaa
    34381 aagaacgtcc gtctactgtt caaagagtac cactacaaaa tacaagaagt agaccaccaa
    34441 tcaaaaccgc caccattaag aaagtcggta agaaaccatg aagttgaaaa ctttagtgat
    34501 tggtggttct ggattattct tgatggtctt ctcactgctt ctgtttgttg ccattttatt
    34561 ttcagatgaa caggacagcg gaatttccaa tattcattat ggaggtgtga atgtttccgc
    34621 agaagtgctg gctcataagc ctatggtaga aaaatatgcc aaagaatatg gcgttgaaga
    34681 atatgtcaac atacttcttg cgattataca ggtggaatcg ggcggtactg cggaagatgt
    34741 tatgcagtcc tcggaatccc tcggtcttcc acctaattca ttgagtacag aagaatccat
    34801 taagcaaggt gtgaagtatt tcagtgaatt attagccagt agcgaaaggc tcagtgtaga
    34861 tttagaatcg gttatccagt cctacaatta tggtggtggt ttcttagggt atgtggctaa
    34921 tcgtggaaat aaatatacct ttgaactggc tcaaagtttc tcaaaagagt attcaggtgg
    34981 cgaaaaagtg tcttacccca atcccatagc catacctatc aatgggggct ggcgatacaa
    35041 ctatggcaat atgttttatg tgcaactggt aacgcagtat cttgtcacaa cagagtttga
    35101 tgatgatacg gtacaagcca tcatggacga agcactgaaa tatgagggct ggcgatacgt
    35161 ttacggtgga gcttccccga ctacttcttt tgattgtagc ggactgacac aatggacgta
    35221 tggaaaagct ggaattaact taccacgaac cgcacaacag caatatgatg tgacccagca
    35281 tatcccacta tcggaagcac aagctggcga tttggttttc tttcattcta cctataacgc
    35341 tggctcttat attactcatg ttgggatata ccttggcaat aaccgtatgt ttcatgcagg
    35401 cgacccaatc ggttatgccg acttaacaag cccctactgg caacagcatt tagtgggagc
    35461 aggacgaatc aaacaatgag aaaggaagat ttaatgatga aatttagaaa aaatcagaat
    35521 aaagaaaaac agataccaaa ggaaaagaaa cctcgtgtct actataaggt caatcctcat
    35581 aaaaaggttg tgattgcctt gtgggtactt ttagggctta gtttcagctt tgcgatattc
    35641 aagcacttta cagctataga tactcatact attcacgaaa caactatcat agaaaaggaa
    35701 tacgttgata ctcatcatgt agaaaatttt gtagagaact ttgcgaaagt ctactattca
    35761 tgggagcaat ccgataagtc cattgataat cgaatggaaa gtctaaaagg ctatctgaca
    35821 gatgaacttc aagctctcaa tgttgataca gtacgcaaag atattcctgt atcgtcttct
    35881 gtaagaggat ttcagatatg gacggtagag ccaactggcg acaatgagtt taatgtaacc
    35941 tacagtgtag accagctcat tacagaggga gaaaatacaa agaccgtcca ctctgcttat
    36001 atagtgagtg tctatgtaga tggttctgga aatatggtac tggttaagaa tccgaccatt
    36061 accaacatac ctaagaaatc aagttataaa ccaaaagcca ttgaaagtga ggggacggtt
    36121 gattccatta caaccaatga aatcaatgag tttttaacga cgttcttcaa gctctatcct
    36181 acagcgacag ccagtgaact ttcctactat gtgaatgacg ggatattaaa accaatcgga
    36241 aaagagtaca tctttcaaga actggtaaat cctattcaca atcgtaagga taatcaagtc
    36301 acggtatcgc tgacagtgga gtatatcgac cagcagacca aagcaacgca ggtatctcaa
    36361 tttgatttgg tacttgaaaa gaacgggagt aattggaaga ttatagaata acaaatattg
    36421 gtacattatt acagctattt tgtaatcacg tactctcttt gataaaaaat tggagattcc
    36481 tttacaaata tgctcttatg tgctattatt taagtatcta tttaaaagga gttaataaat
    36541 atgcggcaag gtattcttaa ataaactgtc aatttgatag tgggaacaaa taattggatg
    36601 tcctttttta ggagggctta gttttttgta cccagtttaa aataccttta tcatgtgatt
    36661 ctaaagtatc cggagaatat ctgtatgctt tgtatgccta tggttatgca taaaaatccc
    36721 agtgataaga gtatttatca ctgggatttt tatgcccttt tgggcttttg aatggaggaa
    36781 aatcacatga aaattattaa tattggagtt ttagctcatg ttgatgcggg aaaaactacc
    36841 ttaacagaaa gcttattata taacagtgga gcgattacag aattaggaag cgtggacaga
    36901 ggtacaacga aaacggataa tacgctttta gaacgtcaga gaggaattac aattcagaca
    36961 ggaataacct cttttcagtg ggaaaatacg aaggtgaaca tcatagacac gccaggacat
    37021 atggatttct tagcagaagt atatcgttca ttatcagttt tagatggggc aattctactg
    37081 atttctgcaa aagatggcgt acaagcacaa actcgtatat tatttcatgc acttaggaaa
    37141 atggggattc ccacaatctt ttttatcaat aagattgacc aaaatggaat tgatttatca
    37201 acggtttatc aggatattaa agagaaactt tctgccgaaa ttgtaatcaa acagaaggta
    37261 gaactgtatc ctaatatgtg tgtgacgaac tttaccgaat ctgaacaatg ggatacggta
    37321 atagagggaa acgatgacct tttagagaaa tatatgtccg gtaaatcatt agaagcattg
    37381 gaactcgaac aagaggaaag cataagattt cagaattgtt ctctgttccc tgtttatcac
    37441 ggaagtgcaa aaaacaatat agggattgat aaccttatag aagtgattac gaataaattt
    37501 tattcatcaa cacatcgagg tcagtctgaa ctttgcggaa aagttttcaa aattgagtat
    37561 tcggaaaaaa gacagcgtct tgcatatata cgtctttata gtggcgtact gcatttgcga
    37621 gattcggtta gaatatcgga aaaggaaaaa ataaaaatta cagaaatgta tacttcaata
    37681 aatggtgaat tatgtaaaat cgataaggct tattccgggg aaattgttat tttgcagaat
    37741 gagtttttga agttaaatag tgttcttgga gatacaaagc tattgccaca gagagagaga
    37801 attgaaaatc ccctccctct gctgcaaacg actgttgaac cgagcaaacc tcaacaaagg
    37861 gaaatgttac ttgatgcact tttagaaatc tccgacagtg acccgcttct gcgatattat
    37921 gtggattctg cgacacatga aatcatactt tctttcttag ggaaagtaca aatggaagtg
    37981 acttgtgctc tgctgcaaga aaagtatcat gtggagatag aaataaaaga gcctacagtc
    38041 atttatatgg aaagaccgtt aaaaaaagca gagtatacca ttcacatcga agttccaccg
    38101 aatcctttct gggcttccat tggtctatct gtagcacagc ttccattagg gagcggagta
    38161 cagtatgaga gctcggtttc tcttggatac ttaaatcaat cgtttcaaaa tgcagttatg
    38221 gaggggatac gctatggctg tgaacaagga ttgtatggtt ggaatgtgac ggactgtaaa
    38281 atctgtttta agtatggctt atactatagc cctgttagta ccccagcaga ttttcggatg
    38341 cttgctccta ttgtattgga acaagtctta aaaaaagctg gaacagaatt gttagagcca
    38401 tatcttagtt ttaaaattta tgcgccacag gaatatcttt cacgagcata caccgatgct
    38461 cctaaatatt gtgcgaacat cgtagacact caattgaaaa ataatgaggt cattcttagt
    38521 ggagaaatcc ctgctcggtg tattcaagaa tatcgtagtg atttaacttt ctttacaaat
    38581 ggacgtagtg tttgtttaac agagttaaaa gggtaccatg ttactaccgg tgaacctgtt
    38641 tgccagcccc gtcgtccaaa tagtcggata gataaagtac gatatatgtt caataaaata
    38701 acttagtgta ttttatgttg ttatataaat atggtttctt gttaaataag atgaaatatt
    38761 ttttaataaa gatttgaatt aaagtgtaaa ggaggagata gttattataa actacaagtg
    38821 gatattgtgt cctgtatgtg gaaataaaac acgattaaag ataagggaag atactgaatt
    38881 aaaaaaattc cccctctatt gtccgaaatg cagacaagaa aatttaattg aaataaagca
    38941 gttcaaagta actgtgatta cagagccaga cgcaaagacg cagagccgat aaaatgagat
    39001 taatacaatc tcattttatc ggctctttcc gttatgtatg gattctttta attagtcttc
    39061 gatgtttctt gcttcgttga taccgctggc taaagattcc attaaggata gttctttgtc
    39121 tgtaaagcta tccatgtatt tctctatctg taatcgtcgg gtgcttttta ccaagttatt
    39181 agcaggtagg ggtcccgagc gcctacgagg aatttgtatc gataagaaat agatttaaaa
    39241 atttcgctgt tattttgtac atttaacttg acggtgacat ctctctattg tgagttatta
    39301 gtggtacagt tttcaaccgt tttaattata aaaaagtggt gcatttttaa attggcacaa
    39361 acaggtaacg gttattgcag gtgtatttct tatctatggg tttaacatgg attttatcat
    39421 taaaatcatg agtattgtcc gagagtgatt ggtcttgcgt atggttaacc ctaaagttat
    39481 ggaaataaga cttagaagca aacttaagag tgtgttgatt gtgcattatc ttaaaatttt
    39541 gtataatagg aattgaagtt aaattagatg ctaaaaattt gtaattaaga aggagggatt
    39601 cgtcatgttg gtattccaaa tgcggaatgt agataaaaca tctactgttt tgaaacagac
    39661 taaaaacagt gattacgcag ataaataaat acgttagatt aattcctacc agtgactaat
    39721 cttatgactt tttaaacaga taactaaaat tacaaacaaa tcgtttaact tctgtattta
    39781 tttatagatg taatcacttc aggagtgatt acatgaacaa aaatataaaa tattctcaaa
    39841 actttttaac gagtgaaaaa gtactcaacc aaataataaa acaattgaat ttaaaagaaa
    39901 ccgataccgt ttacgaaatt ggaacaggta aagggcattt aacgacgaaa ctggctaaaa
    39961 taagtaaaca ggtaacgtct attgaattag acagtcatct attcaactta tcgtcagaaa
    40021 aattaaaact gaacattcgt gtcactttaa ttcaccaaga tattctacag tttcaattcc
    40081 ctaacaaaca gaggtataaa attgttggga atattcctta ccatttaagc acacaaatta
    40141 ttaaaaaagt ggtttttgaa agccatgcgt ctgacatcta tctgattgtt gaagaaggat
    40201 tctacaagcg taccttggat attcaccgaa cactagggtt gctcttgcac actcaagtct
    40261 cgattcagca attgcttaag ctgccagcgg aatgctttca tcctaaacca aaagtaaaca
    40321 gtgtcttaat aaaacttacc cgccatacca cagatgttcc agataaatat tggaagctat
    40381 atacgtactt tgtttcaaaa tgggtcaatc gagaatatcg tcaactgttt actaaaaatc
    40441 agtttcatca agcaatgaaa cacgccaaag taaacaattt aagtaccgtt acttatgagc
    40501 aagtattgtc tatttttaat agttatctat tatttaacgg gaggaaataa ttctatgagt
    40561 cgcttttgta aatttggaaa gttacacgtt actaaaggga atgtagataa attattaggt
    40621 atactactga cagcttccaa ggagctaaag aggtccctag cgcctacggg gaatttgtat
    40681 cgataaggaa tagatttaaa aatttcgctg ttattttgta caataaggat aaatttgaat
    40741 ggtaccataa acgaccgttt atggtacctt ttcattttcc tgctttttct aaatgttttt
    40801 taagtaaatc aagtaccaaa atccgttcct ttttcatagt tcctatatag ttatacttaa
    40861 tgagttatgg tacatttaaa ttataaaatt aaggaggttt ttttatgatt tttggctatg
    40921 ctcgagtgag tacggatgat caaaatctta gtttacaaat tgatgcactt actcattatg
    40981 gaattgataa attatttcaa gaaaaagtaa ctggtgcgaa aaaagaccga ccgcaattag
    41041 aagaaatgat caacctacta cgtgaaggag attctgttgt catttacaag ttagatcgaa
    41101 tttcacgatc aactaaacat ttgattgaac tttctgaatt atttgaagaa cttagtgtca
    41161 attttatatc tattcaagat aacgtagata cttcaacgtc tatgggaaga ttctttttcc
    41221 gagttatggc tagtttagca gaactggaac gggatattat tattgaacga actaactctg
    41281 gtcttaaggc agccagagtc cgaggaaaaa aagggggccg tccaagtaaa ggtaagctat
    41341 caattgattt agctttaaaa atgtatgaca gcaaagagta ttctattcgt caaattcttg
    41401 atgcctctaa attaagcaaa acaacctttt accgttacct caataaaagg aatgcttaag
    41461 atatggctat gaaaagaatt ttaactactt cacagcgtga acaacttctt tctgtagacc
    41521 acttatcaga agaggatttt aaagcgtatt ttagtttttc tgattatgat ctggaggtta
    41581 ttaatcaaca ccgtggaaag gtcaataaac taggatttgc gatacaactt tgtttggccc
    41641 ggtatcctgg gtgttcttta agtaattggc cgattaaatc aaccagacta acttcttatg
    41701 tgagtcgaca gctccatctt gatgcaattg atttaaattc atatgatcat agaaatacac
    41761 gtgcaaatca cttcaacgag atcttagaag tattcaacta tcatcgattc ggtagtgcta
    41821 atacacaaaa acagttaata gaatatttaa ttgaactagc tttagaaaat gatgactcta
    41881 tctatctaat gaaaaaaaca attgatttct taactcgaaa aagaattatt tttccatcta
    41941 tagctacact tgaagacatt ataagccgct gtcgagataa agcagaaaac aacttatttt
    42001 caatattact ctgttcatta acagatatac aaattgaaaa actagagagt ttgtttcaaa
    42061 tttatgaaga gacgaaaata actaaactcg cttggctaaa agacattcca ggtaaggcaa
    42121 atccagaaag ctttatgagt atttgtaaaa aagtggaagt gattgcttcc atgggactcg
    42181 ggacaattaa tgtctcccat attaatcgga acaggtttct tcagctagct agactagggg
    42241 aaaattatga tgcatatgac ttctcccgtt ttgagcttga aaaaagatac tctttactta
    42301 ttgctttttt agtcaatcat catcaatatc tgatcgatca actgattgag attaatgacc
    42361 gcattttagc aagtattaaa cgcaaaggga cacgtgattc acaagaacag ttaaaagaaa
    42421 aaggaaaatt ggctactaaa aaattggaac attatgcttc tttaattgat gctcttcact
    42481 ttgcaaaaga taatgatagt aatccttttg acgaaattga acgaatcatg ccttgggaag
    42541 atttagtaca agatggagaa gaagctaaaa aaattacagg taataaaaat catggctatt
    42601 tagaaatggt tcgaaataaa gctaattacc tccgaagata cacgccaatg ttattgagga
    42661 ccctttcgtt caaagcaact ccggcagcaa atccagtcct catggcccta actcaactaa
    42721 ctgatttaca caatagtggt aaaagaaaaa taccggcaga tacttctact gattttgtga
    42781 gtaaaaaatg gaaaagcctt gttcggccag aagaggggaa aatagatcgg tcttactatg
    42841 agttagtagc tttcaccgag ctaaagaaca atattcgatc aggagatatt tcagttgaag
    42901 gaagtatgat ccatcgaaat attgatgatt acttagttga tttatctgct tgtattgatt
    42961 cagaaactat tccagacacg tttgaggact atttaaagga tcgggaaata attttagatt
    43021 tacagcttca attttattcg acagttgata agagaatttc aagagcaaac cttaaaaagt
    43081 tggaaaaagt tacacctagc gaagcagaaa tatatagaaa aaaactttat tcaataattc
    43141 ctaagataag gcttagtgat cttttaattg aggtggacag ttggaccaac ttttcacaag
    43201 aatttagtca tgattctaca gggaaaccgc cgagtgaaca agaaagaaaa attatttttg
    43261 ctgctttgct gggtttaggg atgaatattg gtcttgaaaa aatggcccaa tcaactcctg
    43321 gaatttctta ttctcagtta gccaatgcca aacaatggcg cttttataaa gaagctctga
    43381 ctcgtgctca atctgttttg gttaattatc agttaaagct tcctgttgca gacttttggg
    43441 gtgaaggaaa aaccactgct tcagacggaa tgcgcgtccc agtgggcgtc tcagctctaa
    43501 aatccgatgt taatccacat tacaaaagta tggaaaaagg agctacaatg attcgatcaa
    43561 taaatgatag gcatacgact catcatatcg aggttgcttc aactaataca agggaagcta
    43621 ctcataccct tgatggccta ctttatcatg aaacagatct agatattgag gaacatttta
    43681 ctgatacaaa tgggtattct gatcaggtgt ttggaatgac cgcattacta ggctttgatt
    43741 ttgaacctcg catcagaaat ataaaaaaat cacaattatt ttctatcaaa tcaccttcct
    43801 actaccctaa cttatcagaa gatataagcg gaaaaatcaa tgtaaaaatt attgaagaaa
    43861 actatgatga aattaaacga atcgcctatt cgattcaaac aggaaaagta tctagttctt
    43921 tactattagg aaagctaggc tcatacgcac gtaagaatag agtagctctt gcactgagag
    43981 aactaggtcg cattgaaaag agcattttta tgatagatta tattacagat agtgagctac
    44041 ggcgaaggat cactcatgga ctaaataaga cagaagcgat taatgcttta gctagagaac
    44101 tattttttgg gcgacgcgga aaatttatgg agcgcgatat tcgccgacaa cttcaaagtg
    44161 ctagtgcgct taatgtgtta ataaatgcaa taagtatatg gaacgccgtc tacttacaag
    44221 cagcttataa ttatctcgtc aaaatagatc ccgaagtaac taagtatatg aagcatgtat
    44281 ctcctattaa ttgggagcat atcacttttc ttggagagta taaatttgac ttgttatcta
    44341 ttcctaaaca cttaagagaa ttgaatataa aaaataaata ggccttgaaa cattggttta
    44401 gtgggaattt gtacccctta tcgatacaaa ttcccactaa gcgctcggga ccccaggtaa
    44461 gaaaaattca tcaacggaaa catgaagtaa cgatacaagg tcataaagaa cttgtatgct
    44521 ggggtgttgc cctttatttt caatattagt taagtaccgt gggtcaattt caatcaatgc
    44581 tcccacttgt tcacgagtta aacctcgttt caatcgagct tctttaatgg ctaaaccaaa
    44641 ggctctaaaa tcatatttat cttctttttt acgcatagta gaccacctct atacatttta
    44701 ttgttcctac tgaattaaaa acaggtatag aaaaacgtgt tatatggttt ataggtttat
    44761 atttaataaa aagcactact aaacgccaat aaaaaaaacc gttatatggt agtgctattt
    44821 acgctgttaa aatattgtat attacttcca aatggcggtt tgttggaggt caacgtcgcc
    44881 atgaagtaca tcatatacaa taaatttcct tacattgggt tcttgtcaaa aaaagtcgtc
    44941 tatctgcaat agataagtac gtccaccaat gtggttttat aaatcatata gatagaataa
    45001 cagaagcatg taaacagaga aataaatctg tttatatgct tttttggcta ttcagaactt
    45061 ttttacaaag tttatttatc agtaatgcaa caaatccccc tttcacattg ggactaagag
    45121 tgaaaggaga taaacgagca aggctcactt cctttcctag acagaaaggg ggtgagaaac
    45181 atgaaaccat cttcttttca gaccacaata gaaaatcagt ttgactatat ctgtaaacgt
    45241 gctatggaag acgagcgaaa gaattatatg ctttatcttt caaggattgc aaagcgtgag
    45301 gtgtcctttt cggatgttgg cgattatctt gttagccagt ttgcgacaac agataactat
    45361 tcaactgact ttcagatttt tacactcaat gggttatcag taggcgttga aaatgatttg
    45421 ttgagtgaag cattacgtga gttgccagac aagaaacgtg aaattctact gctgttttac
    45481 tttatggaca tgagcgattc agaaattgca gacctgttga aattgaaccg ttctactgtc
    45541 tatcggcata gaaccagtgg actagcctta attaaaaagt ttatggagga atttgaagaa
    45601 tgaaaacaca atatcctatg attccctttc ctctcattgt aaaggcaaca gatggcgata
    45661 ccgaagcgat taaccagatt ctacatcatt acagagggta cataacgaag cgttccctac
    45721 gacttatgaa agatgaatat ggcaatcaaa gtatggtcgt tgatgaagtc ttacgtggaa
    45781 gaatggaaac cagactgatt acaaagattt tgtcatttga aattaagtaa tatcctctct
    45841 cctttcgtgg aagcgtgcta aaccattcca cgcttcccga acagggaggt ttgttattcc
    45901 accaaagcat attgagcttt caatgtgttt tgataggcta acgagccatt gttctttgaa
    45961 aactgaataa aagtaatcga atacgtttcg ataagaaaag agccaacgga actaaccgcc
    46021 atgacctatc ttataaagat agcgagcgat tcatgttagt gatccgagaa gcaatcttta
    46081 gcaggattgc ctgcaacgac attcttatcg tgataatgat actcccatac agtcaatagt
    46141 ccgagcgtga taaaaccgtc gcaggcaatg agtatggcta catgagaacc atgcaggggt
    46201 ggaactcccg tgagctttgc taaagctgtt cgattgctgg taaaacaact tttatgaaat
    46261 ccaaataagt gatttggaaa ggaggatttt atgaagcaga ctgacattcc tatttgggaa
    46321 cgttataccc taaccattga agaagcgtca aaatattttc gtattggcga aaacaagcta
    46381 cgacgcttgg cagaggaaaa taaaaatgca aattggctga ttatgaatgg caatcgtatt
    46441 cagattaaac gaaaacaatt tgaaaaaatt atagatacat tggacgcaat ctagcgtcgc
    46501 caaagggtct tgtatatgat aaaatagtat taagtcgtat caaggctctt tccataaagg
    46561 aaaggagcaa atgccatgtc agaaaaaaga cgtgacaata aaggtcgaat cttaaagact
    46621 ggagagagcc aacgaaaaga cggaagatac ttatacaaat atatagattc atttggagaa
    46681 ccgcaatttg tttactcgtg gaaacttgtg gctacagacc gagtaccagc aggaaagcgt
    46741 gattgtatct cacttagaga gaaaatcgca gagttacaga aagacattca tgatggtatt
    46801 gatgttgtag gaaagaaaat gacactctgc cagctttacg caaaacagaa cgctcaaaga
    46861 ccaaaggtta gaaaaaacac tgaaactgga cgcaaatatc ttatggatat tttgaagaaa
    46921 gacaagttag gtgtaagaag tattgacagt attaagccat cagacgctaa agaatgggct
    46981 attagaatga gtgaaaatgg ttatgcttat caaaccatca ataactacaa acgttcttta
    47041 aaggcttcat tctatattgc tatacaagat gattgtgttc ggaagaatcc atttgacttt
    47101 caactgaaag cagttcttga tgatgatact gtccctaaga ccgtactaac agaagaacag
    47161 gaagaaaaac tgttagcctt tgcaaaagct gataaaacct acagcaaaaa ttatgatgaa
    47221 attctgatac tcttaaaaac aggtcttcgt atttcagagt ttggtggttt gacacttcca
    47281 gatttagatt ttgagaatcg tcttgtcaat atagaccatc agctattgag agatactgaa
    47341 attgggtact acattgaaac accaaagacc aaaagtggcg aacgtcaagt tcctatggtt
    47401 gaagaagcct atcaagcatt taagcgagtg ttagcgaatc gaaagaatga taagcgtgtt
    47461 gagattgatg gatatagtga tttcctcttt cttaatagaa agaactatcc aaaagtggca
    47521 agtgattaca acggcatgat gaaaggtctt gttaagaaat acaataagta taacgaggat
    47581 aaattgccac acatcactcc acatagtttg cgacatacat tctgtaccaa ctatgcaaat
    47641 gcaggaatga atccaaaggc attacagtac attatgggac atgctaatat agccatgacg
    47701 ctgaactatt acgcacatgc aacattcgat tctgcaatgg cagaaatgaa acgcttgaat
    47761 aaagagaagc aacaggagcg tcttgttgct tagtagtaca aatgaattta ctacttattt
    47821 accacttctg acagctaaga catgaggaaa tatgcaaaga aacgtgaagt atcttcctac
    47881 agtaaaaata ctcgaaagca catagaataa ggctttacga gcatttaaga aaatataaaa
    47941 agataattag aaatttatac tttgtttatt tataaaaaaa ctaaatgaat tgattttaaa
    48001 gaaataaaat gctaacatat atagtagatg ttagtatttt atttctaaga aaggagaatg
    48061 atatggttga taaaagagag aaactgatga actctttcaa tcagtatggt tttttaactt
    48121 ttaaacaagt aatagatgaa aatttacact acaaaacctt attaaaaatg gttgcagaag
    48181 gaaaaatcga tgctgaagaa aaagggttat atcgcttacc tgatatttat ttagatgagt
    48241 ggtttgtcct tcagtatcga tttccaaagg gaatcttttc tttggagaca gcactttggt
    48301 tacatggttt atctttgact atccctttta acatgacgat gagttttcct tatggtacga
    48361 ataccaaaaa cattaaggaa gcagatatat gtcctattat cttacgctct cactatagtg
    48421 aaggaattat tgaaatagag cgccttcctg gtcaatttat taaagtttat gaagttgagc
    48481 gagttttggt tgaatgtcta agaccagttc atcaggtgga tcttcaaatt attgcaccag
    48541 cgtttaaaaa atattttcaa caaaataaaa ttcatttaca caaattattt tattatgccc
    48601 agctatttaa agtaactgat aagttacaat cttatacgga ggtactatct taatgttttc
    48661 aaatgcgaat agctttaaag caaaaatcaa aaacatttca aaagataagg gaattccagc
    48721 tcaacaagta caacaacatt atttaattga gcaagtgtta aagctgattt ctactagttc
    48781 ttatagagat tccttcattg taaaaggagg gtatctaata ggtcaaatga ttggactaga
    48841 taagcgaacc acaatggatt tagatgtcac tctgaaggga accgaaatga gcagagaaaa
    48901 tttgattcat atctttgaag agattctttg ttctaatact gatggatttt cattttcagt
    48961 agataagcta gaacctattc gtcaagatga tgaatatgga ggattttcat taaaattaaa
    49021 tgcaactttt gatacattaa aagaggttgt ttttattgat attactactg gtgataaaat
    49081 cacaccaaga gaaattactt attcaatgac ttctatcttt actaatgaaa gcatcaagat
    49141 atggacatat aatctagaga ctgtacttgc tgaaaagtta gaaacaatca tcagtagggg
    49201 actagcttcg acgcgtccac gtgatcgata tgatcttttc accttgtata aacttagaaa
    49261 agaagagatt aatcttgaag tattaaaaaa tgcacttgag aatacggcag aaaaacgtaa
    49321 aagtaaagat actatttata attgggaaga acaagtgaga ggaattgaaa tttctgatta
    49381 tcagaaagag ctatggattc gttatcaacg ccaatttaag tatgctaaag atatctcatt
    49441 tgataactct gttcaggtca ttagggaaat tatgcaacaa atattttagt acaaaagtaa
    49501 ctcattagta aagcagtgag ttgctttttt tattccaata actccaaaaa tgtgataaaa
    49561 atttcaacta ctcttatcta taataaagct acctgttctt tgaaaattga atccactccg
    49621 tcttgattag cgtgcctgtg taagtaggga ctgagagtat ttccctgtga agggcaactg
    49681 gcacaagacg tgtgtgagaa ttttctaaca gacacggagt ttatcgttac cagacttaaa
    49741 cgatgcgaca aactagataa aggagttaat catgaaggta gtaaacttgt atgatttgaa
    49801 acaaatggga aataaaggtg gttgtaccat ccaattgatt catcactttc cttttggtat
    49861 gggcttagga catctcaaaa aagactacat tgaatttaaa cgtgttggta tcgttgatgg
    49921 gaaggcagta gaagtcactc ttcgagaacc ttattcgaga gatctactgc aggttgtcaa
    49981 gtcgattaag caacgtcaga aattgatagc ttatcgttat aaagaaggaa agctgctatt
    50041 tgtgaagaag gaggcatcag atgtcctctg aacaacagga acgaatggca gttcaatatg
    50101 cggagcgtag tcttttattt actgtcaaaa gtctcttaaa aattctagaa tggtctagac
    50161 gtcaggcttt agcacaggat tccgcctata agataggggt gcagaaatta gaagaattgc
    50221 tacaatctcc ttattcgatt gatacgatta atctgaaaaa agatttttta gacaaaccaa
    50281 ttgatataga gaaatttaaa gcttttttag aaaaagaaga gattccttta gccatcgctt
    50341 ggcaagggga ttctctacat ttctacacga aagaccgttc gattctggac aatcatttag
    50401 accatctgtt agaaaaaatg gttaatgatc cggagaaatt agctgatttt accatggata
    50461 agtcattaga cgatgcaatt gatgaggcga aatcccaaat tacctttaga caagaagggg
    50521 ccgtcaaaca gaaagagatg gtgagatgat gtacagtgga aagaaattcc tactattttc
    50581 actgttaggt atcttactag gctatctttt tcatcgtttg acgcttttgt atgattccta
    50641 tactggaaat acattagata aatggactca tcttctgatg gaaggtcaag atgaagttct
    50701 tcagtcgcca tggaatgttt cctttactgg aaaatccagt gctttttttc tactaggctt
    50761 tgtgatgatg ttgctggttt atctttattt agagactggc aaaaaacaat accgagaagg
    50821 ggtagaatac gggagcgccc gttttggaac tctaaaagaa aagaagctct tttacggtaa
    50881 ggaattttct catgatacga tcttagctca agatgttcgt ttgacattat tagataaaaa
    50941 acccccccaa tatgatagaa ataagaatat tgcggtgatc ggaggttcag gaagtgggaa
    51001 gacatttcgc tttgtgaaac ctaatcttat tcagatgaat agttctaata ttgtagtgga
    51061 tcctaaagat cacttggccg aaaaaacagg caaactcttt ttagaacatg gctatcaagt
    51121 aaaggtgcta gatttagtca atatgaagaa ctcagatggc ttcaatcctt ttcgctatat
    51181 agagacagaa aatgatttga atcgcatgct gacggtttat tttaataaca ccaaaggctc
    51241 tggctcccga agtgacccat tttgggatga agcttctatg actttggttc gagctttagc
    51301 ctcttacttg gtcgatttct ataatccacc caaaacaaga gaacagctca ttgaagagag
    51361 tcgtttgagt caaaaagaat accagaactt gttgaaacgt caaaaaaaag aagtggaaga
    51421 gcgaaaaaaa cgaggacgtt atccaagttt tgctgaaatc tcaaaactca ttaaacactt
    51481 atctaagggt gaaaaccaag aaaaaagtgt cttagaaatt ctatttgaaa attatgctaa
    51541 aaagtatggc actgaaaatt ttaccatgcg aaattgggca gatttccaaa attataagga
    51601 taagactctg gattctgtta tagctgtaac cactgctaaa tttgccctct tcaatattca
    51661 aagtgtcatg gatttgacca aaagagatac ccttgatatg aagacatggg gccaggaaaa
    51721 atcaatggtt tacttagtta tcccagataa cgatagtacc tttcgctttc tttcagccct
    51781 ctttttttca accgtatttc aaaccctaac aagacaagca gatattgatt ttaagggtca
    51841 attgcctctt catgtgagag tctacttaga tgagttcgca aatataggag aaatcccaga
    51901 ttttgctgaa caaacctcaa cagtccgttc tcgaaatatg agtctcgttc ccattcttca
    51961 aaatattgcc caacttcaag ggctctataa agaaaaagaa gcttggaaaa ccattttggg
    52021 gaactgtgat agcttagtct acttaggtgg gaatgatgaa gataccttta aatttatgag
    52081 tggcttactc ggtaaacaaa ccattgatgt tcgaaatact agtcgttcct ttggccagac
    52141 aggttcagga tccctttctc atcaaaagat tgctcgtgat ttaatgacac ctgatgaggt
    52201 cggaaatatg aaacggcatg aatgcttggt tcgaattgcc aatatgcctg tctttaaaag
    52261 caaaaaatac aattccacta agcatccaaa ctggaaatac ctagccaatc aagaaaccga
    52321 tgaacggtgg tggaactatc aaatcaatcc tttgaatcaa agacaagaaa atcatcttga
    52381 aggccttaga attcgtgatt taacttttga atctagttta aaataaaaat agaaaagagg
    52441 aaatagatga ttacgcattt taaaggtttt gtttatggag tagacgcaag tgctatgttt
    52501 gcacaagcta tgtctttgtt acagaagggt ttgattgcgg ttggtgcctt tctcgttgtt
    52561 gtggggattg tcaatcttgc aaccaacatt aaagatggtg gaccaggtgt tcggaatgcc
    52621 attctggaaa ttgtcggtgg tgttatggta ggggctgctg gagcctttgt aactcaaatt
    52681 tcaatttagg aggataaaca atgacatgaa tcttagttta gtctcaccct ttgtttacct
    52741 tgcatctgaa aaaatatcag ctgaaaattt atttgaaggg tttaatgtag atttacaatc
    52801 tacggtagat ctgattaaat ccctatctag ctacaatcca acagtttgga cttatatgtc
    52861 tagtattact aaaagtgtca tgcagcctct tggagttgcg attttatcag ttgttctcat
    52921 cttagaattt tcgaagatgg caaagaaaat tgctaactca ggaggagcga tgacctttga
    52981 agcattagcg ccgatgttga ttagttatat catggtcgca gtcgtgatta ccaatactac
    53041 cgttattgta gaagccatca tcgggattgc gagtcacgcc attgaacaag tggcctcaat
    53101 tgtggctcac ggtggggcaa agtatgatac catctctgga ttaaaaggtt caggatttat
    53161 tggccggatg attgtgggct ttttcgccct cctcatttgg ctagttcgga tagtaagtgc
    53221 agccatggtt aaccttttgg tatctattcg atttattcaa ctctacctta tgattccatt
    53281 tgcccctctt acgattccaa catttttaag tgatgaatgg aagtctattg gtattggcta
    53341 tttaaaaaat attatggttt atgcggtaca aggggttctc atttttctga ttgtttctct
    53401 tgttccttta tttgaatctg ctgggaaaat agctgtttca aatggtgcag gagtcttgca
    53461 atcacttgcg attatgtttg gtagtttggt acaagctatc ttactgatta ttgccctcgt
    53521 tggttctcaa cgtacggctc gctcaatctt aggtatgtaa ttagataaag gctaggaagt
    53581 gattgcttct tagccttttt agaaaggaaa gtcatgaata cacgtgtctt taaagacatc
    53641 tcaaaatacc aacacagggc ttggttaggt ttcaccacaa gacaaatcat ctttgtttta
    53701 ccagccttta ttgtcacaat tattgttttg ggcttgaatc tctttttctg gcaatttgga
    53761 gattggtttg tttacggttt tgtgtttgct tttaccatcc ccctcatgct ttttggagtc
    53821 tataaaccca atgatttata ttttgaacat tatttgaaat accgtcttca ttttgaacta
    53881 acggttcccc tacgcacaat tacaggaaag aaaggacctg aacatgaaaa gaaaatcaaa
    53941 tacattaaag aaacaaaaaa cttcaatgac taatcagaaa gaagtagtta aaggaaaaaa
    54001 agaggaagtg ttaccatcga cggctaatac tctttcctat caagccctgt atcaaaatgg
    54061 tctgatgcag gtaaaagaag attatttctc acaaagctat ttacttggtg atgtcaatta
    54121 ccagactgtt ggtttagaag ataagggcgc aatcattgag aagtattctg atttgattaa
    54181 ctccctagac gaccaaacca acttccaatt gactatcttt aataaaagat tgaatttaga
    54241 aaagtttaga caaagtgttt tgtatgagga aaaagaagat gggtatgata gctatcgtaa
    54301 agaattgaat cggatgatga atcagaattt agacagtggt gaaaataact tttcagctgt
    54361 gaaactgatt agctttggta gaaaggattc taatcccaaa caagcctatc gttccttgtc
    54421 tcaaattgga gaatatttca agagtggttt ctcagaaatt gatgctcgat ttgaatcttt
    54481 ggctggagaa gaacgggtga acttgctggc agatatgctt agaggagaac accatcttcc
    54541 tttttcttac cgtgatttaa cgagatctgg tcagacaact cgtcacttca tagcacctaa
    54601 tctcttggat tttaaaaaca agaattacct acaaatcaat gaccgcttat tgcagattgt
    54661 ctatgtcaga gactacggta tggaattagg agatcagttt atttgagacc tcatgcaagg
    54721 agatttggaa ttgattgtga gcctccatgc tcaaagttcg accaaggcgg atgctatgaa
    54781 gaaactacga acaaagaaga ccttgatgga atcccaaaag attggggaac aacaaaaact
    54841 tgctcgtaca ggtatctatt tggaaaaagt aggtcatgta ttagaaagca atatcgatga
    54901 agctgaggaa ctcttaaaaa ccatgaccga gacaggagat aaactatttc aaacagtatt
    54961 cttgattggt gtttttggtc aggatgaaga agaacttaaa caagctctag atacgattca
    55021 acaagtggcc ggctcaaatg acctaatgat tgataaacta ccatatatgc aagaagcagc
    55081 ctttaatagt ttgctgccat ttggttgtga ttttttagag ggagtatcac ggagtttatt
    55141 aacatccaat atagcagtga actctccatg gacttcagta gacttacaag accgtagtgg
    55201 aaaatattac ggtatcaatc aaatctcaag caatattatt accattgatc gcagcctatt
    55261 aaatacaccg tctggtctga ttttagggac atctggagct gggaaaggga tggcaaccaa
    55321 gcatgaaatt atcacgaccc aaatcaagga atctggtgaa aatactgaaa ttatcatcgt
    55381 ggatccagaa gcagaataca gtgtcattgg acgagctttt ggtggagaaa tgattgatat
    55441 tgcgcccgat tcccaaactt atctcaatgt ccttgatttg tctgaggaaa atatggatga
    55501 agatcctgta aaggtaaaat cagaatttct tttatccttt atcggcaagt tattggatag
    55561 aaaaatggat ggaagagaaa aatcgattat cgaccgagtc acaagactca cctatcagtc
    55621 atttaaagag ccttctttgg aagaatgggt ctttgtcttg agccaacaac cagaagaaga
    55681 agcgcagaat ttggcacttg atatggaact gtatgtcgaa ggttctcttg atattttttc
    55741 tcataagacc aatattcaga caggatctaa tttcttgatt tataacgtta agaagttagg
    55801 agatgagctg aaacaaatcg cccttatggt tgtttttgat cagatatgga atcgtgtcgt
    55861 tcggaatcaa aaattaggga agaagacctg gatttatttt gatgaaatgc agcttctctt
    55921 attagataaa tatgccagtg atttcttctt taaattgtgg agtcgtgtca gaaaatatgg
    55981 agccagtctg actggaataa ctcaaaacgt cgaaacctta ttgttagatc caaatggtag
    56041 acggattatt gcaaatagtg aatttatgat tcttctcaag caagcaaaaa atgaccgaga
    56101 agaactggtt caactcttag gcttgtcaaa agaactcgaa aaatacctag tcaatccaga
    56161 aaaaggagca ggactgataa aagctggttc agttgtcgta ccatttaaaa ataagattcc
    56221 tcaaggtact caattgtttg atattatgag tacggatcct gataaaatgg cttctaatta
    56281 aggggaaggt aaatgaagga taaaagagaa atcatacgtg cccgaaaagc atttagaaga
    56341 agtctaaaag atgagaagaa attcttgaaa caaggaaaga aggaggtgag gaaacagaaa
    56401 aaagattccg ctgtactgga tgaaaaagca tggaaaaaag agataaaaga aaagctagag
    56461 gagatgagag aagcttcaaa ggagagagta aaacaagcaa atgaagacta caatcatatt
    56521 cttcaaaata gtcctccatc ttttttgaat cgtaaagaat taagagacag acgattacct
    56581 catgctagga aacgattgaa aatagccaag aagcaattta gagaagccaa ggtagaagca
    56641 aaagaagaaa gaaaagagag tcgtaaagaa agaaaaacca atcaaaaatt tctctacggt
    56701 caggaatcga aacaaaaatc taattttttc tttcaaggga agagtttaga agaattaaaa
    56761 gctaagaaag aagtcaaggc tgctaaagaa aatttaaaat ctactaaaca agcctataag
    56821 tacaaaaaag tcagtaggaa agccaaaact tttctttatg tccttggacg tgaaggtgga
    56881 gagttagctt cagaaaatga agatttagaa ggctatcgca cacttcaaga gaccattaga
    56941 aaagggaaac gctacagtcg gctttcttat aatcttggaa aagctagtgt caaaacagga
    57001 caagcaacag gtcgttttac caagaaaaga ctgaccaaca caaaagagcg ataccatcat
    57061 tttaaggatg gaaaaggatg gaaactagca aaagataacc caagttcctt taagaatcgg
    57121 tttcgaaaat taaagaaaca aggtctttca agtgtccaaa atatctatca aaaactaaaa
    57181 gcagcctttt ccttctttac atttgcggct ggaaatcctg caacatggat agttggagga
    57241 atagtctttc ttcttttact tatgatgagc ttcttcttag gattttcatc tgctagtttg
    57301 attcaacaag atgaatttga attaacaaaa gcttataccc acctaacttg ggaagatgca
    57361 gaacatactc gcacaaatga caaaggaatt acctattaca caaaagttga tgatgtgatg
    57421 gggtatatga actttaaatt ccatgactat gagttacaga aaccagttca cttatttagt
    57481 tcagaaactt acaaggatta tctgtctact ttgtggcatg atttaaacga tggtgatgat
    57541 ttgaaatcca tgcaagacct ctatgaaact cctaagtata aactatcgaa agacgatcaa
    57601 gaggaaataa aggaactaaa agaagaaggt gtgtatgctt ccatgcagga attagacaat
    57661 ccatttgagg gacaaagcaa cgaagatagt ctaaccatga cttatcgtta tggatactat
    57721 gatttagatg ggaaacctac tcttcaggag tacatcctac tagaagcaaa ggctcaccaa
    57781 acgattgtcg caccaatgga tgcagttgta tctctagatg gtgacaatat tattctcact
    57841 aacggaaaag gagagaatga gagtcgatta accttgtatt ctattcataa tggccgtgcg
    57901 attgagggga caagagtcct aacgggtgat attattggtg aaacaccaga cgatacaggt
    57961 ttgaaagttt cctatcaaaa gtataagaac aagaaagaaa aattggtgta tgtcaatccg
    58021 caattttatt ttccaaaagt cattcaactt cagaccacta tcttacctgc cattggtcag
    58081 tttggtgggg atgagtttga acgagcaaaa catatttatg attttttgaa atctcaaggc
    58141 gtaagtcccc aagccattgc ggctatttta ggaaattggt ctgtagagtc ttctattaat
    58201 ccaaaacgag ctgaaggaga ttatttatct cctccagttg gcgctaccga ttcctcatgg
    58261 gatgatgaaa gctggttagc gattggaggt ccagccattt atagtggtgc ttatcctaat
    58321 attcttcata gaggtttggg gttagggcaa tggacggata cttcagatgg ttcaacacgt
    58381 tatacagctt tattgaatta tgcacatagc aaaaataaga agtggtatga tttagacctc
    58441 caacttgatt ttatgcttca tggggatagt ccttactacc aaagttggtt aaaagatttc
    58501 tttaaaaata cgggcagtgc agccaatctc gcccaactct tcctcaccta ttgggaggga
    58561 aattctggtg acaaattact ggaaagacaa accagagcaa cggaatggta ttaccaaatt
    58621 gaaaaaggct tcagccaaac aaatggagga caggcaaaaa gtgacccaca atcccttgaa
    58681 ggggttcgtg gggacttgta tgatcattct gttcctggtg gtggagatgg tatggcctat
    58741 gcctatggac aatgtacatg gggtgttgcg gctcgtatga atcaattagg cttaaaatta
    58801 aaaggaagta acggagagaa gatttcaatc attaatacca tgggaaatgg tcaggactgg
    58861 gttgcgacag cttcaagtct tggtggggaa actggctcta caccaagagc aggtgctatt
    58921 gtttcttttg tgggaggtac acatggcaca ccagcagact atggtcatgt agcttttgt
//
LOCUS       DAVDZK010000008        57448 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVDZK010000008 DAVDZK010000000
VERSION     DAVDZK010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57448
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.008"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            1..73
                     /locus_tag="VUX16_000566"
     tRNA            1..73
                     /locus_tag="VUX16_000566"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Met,seq:cat)
     gene            87..160
                     /locus_tag="VUX16_000567"
     tRNA            87..160
                     /locus_tag="VUX16_000567"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            171..260
                     /locus_tag="VUX16_000568"
     tRNA            171..260
                     /locus_tag="VUX16_000568"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Ser,seq:tga)
     gene            271..344
                     /locus_tag="VUX16_000569"
     tRNA            271..344
                     /locus_tag="VUX16_000569"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:305..307,aa:Met,seq:cat)
     gene            348..420
                     /locus_tag="VUX16_000570"
     tRNA            348..420
                     /locus_tag="VUX16_000570"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:381..383,aa:Phe,seq:gaa)
     gene            440..510
                     /locus_tag="VUX16_000571"
     tRNA            440..510
                     /locus_tag="VUX16_000571"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:472..474,aa:Gly,seq:tcc)
     gene            546..619
                     /locus_tag="VUX16_000572"
     tRNA            546..619
                     /locus_tag="VUX16_000572"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Ile,seq:gat)
     gene            626..713
                     /locus_tag="VUX16_000573"
     tRNA            626..713
                     /locus_tag="VUX16_000573"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:660..662,aa:Ser,seq:gct)
     gene            complement(839..1774)
                     /gene="birA"
                     /locus_tag="VUX16_000574"
     CDS             complement(839..1774)
                     /gene="birA"
                     /locus_tag="VUX16_000574"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HET8123588.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDIDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRTFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1771..2631)
                     /locus_tag="VUX16_000575"
     CDS             complement(1771..2631)
                     /locus_tag="VUX16_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET8123589.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2739..4901
                     /locus_tag="VUX16_000576"
     CDS             2739..4901
                     /locus_tag="VUX16_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET8123590.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRRHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKNLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRRL"
     gene            4936..6195
                     /locus_tag="VUX16_000577"
     CDS             4936..6195
                     /locus_tag="VUX16_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET8123591.1"
                     /translation="MEWYKKIGLLATTGLALVGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6209..7075
                     /locus_tag="VUX16_000578"
     CDS             6209..7075
                     /locus_tag="VUX16_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET8123592.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7089..7922
                     /locus_tag="VUX16_000579"
     CDS             7089..7922
                     /locus_tag="VUX16_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET8123593.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7923..8003
                     /locus_tag="VUX16_000580"
                     /pseudo
     CDS             7923..8003
                     /locus_tag="VUX16_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8281..9723
                     /gene="gtfA"
                     /locus_tag="VUX16_000581"
     CDS             8281..9723
                     /gene="gtfA"
                     /locus_tag="VUX16_000581"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET8123594.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVSEIDLQNQTYRVIENGVEVTF"
     gene            9861..11054
                     /locus_tag="VUX16_000582"
     CDS             9861..11054
                     /locus_tag="VUX16_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET8123595.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11741..13720
                     /locus_tag="VUX16_000583"
     CDS             11741..13720
                     /locus_tag="VUX16_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET8123596.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13787..15283
                     /locus_tag="VUX16_000584"
     CDS             13787..15283
                     /locus_tag="VUX16_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8123597.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15283..16209
                     /locus_tag="VUX16_000585"
     CDS             15283..16209
                     /locus_tag="VUX16_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8123598.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16218..17285
                     /locus_tag="VUX16_000586"
     CDS             16218..17285
                     /locus_tag="VUX16_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123599.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKICEKMGFAHLAD"
     gene            17296..18222
                     /locus_tag="VUX16_000587"
     CDS             17296..18222
                     /locus_tag="VUX16_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123600.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(18297..19553)
                     /locus_tag="VUX16_000588"
     CDS             complement(18297..19553)
                     /locus_tag="VUX16_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET8123601.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKMSMTDIAHQLSISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQIFPCAKIVLDRFHIIQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILNKLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGL
                     IEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFRKRIFIALNIKKERTKFVLSRA"
     gene            complement(19708..20418)
                     /gene="treR"
                     /locus_tag="VUX16_000589"
     CDS             complement(19708..20418)
                     /gene="treR"
                     /locus_tag="VUX16_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET8123602.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFLEFRMVWKVGRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            20603..22570
                     /gene="treP"
                     /locus_tag="VUX16_000590"
     CDS             20603..22570
                     /gene="treP"
                     /locus_tag="VUX16_000590"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET8123603.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTINRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKIEGDTNLQAEFVAQEEAEFVSHEPVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVIVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATITGTYPTTIQAGASLMVATRI"
     gene            22748..24373
                     /gene="treC"
                     /locus_tag="VUX16_000591"
     CDS             22748..24373
                     /gene="treC"
                     /locus_tag="VUX16_000591"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET8123604.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            24629..24877
                     /locus_tag="VUX16_000592"
     CDS             24629..24877
                     /locus_tag="VUX16_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET8123605.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            25084..25878
                     /gene="racE"
                     /locus_tag="VUX16_000593"
     CDS             25084..25878
                     /gene="racE"
                     /locus_tag="VUX16_000593"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET8123606.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            25875..26846
                     /locus_tag="VUX16_000594"
     CDS             25875..26846
                     /locus_tag="VUX16_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET8123607.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            26822..27343
                     /locus_tag="VUX16_000595"
     CDS             26822..27343
                     /locus_tag="VUX16_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET8123608.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            27340..27801
                     /locus_tag="VUX16_000596"
     CDS             27340..27801
                     /locus_tag="VUX16_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET8123609.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            27792..28532
                     /gene="xerD"
                     /locus_tag="VUX16_000597"
     CDS             27792..28532
                     /gene="xerD"
                     /locus_tag="VUX16_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET8123610.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            28532..29260
                     /locus_tag="VUX16_000598"
     CDS             28532..29260
                     /locus_tag="VUX16_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET8123611.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            29279..29848
                     /locus_tag="VUX16_000599"
     CDS             29279..29848
                     /locus_tag="VUX16_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET8123612.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            29835..30557
                     /locus_tag="VUX16_000600"
     CDS             29835..30557
                     /locus_tag="VUX16_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET8123613.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            30557..30799
                     /gene="yidD"
                     /locus_tag="VUX16_000601"
     CDS             30557..30799
                     /gene="yidD"
                     /locus_tag="VUX16_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET8123614.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMSLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(31024..31989)
                     /locus_tag="VUX16_000602"
     CDS             complement(31024..31989)
                     /locus_tag="VUX16_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET8123615.1"
                     /translation="MKTSLKLYFIALVASFLLLLGACSTNSSTSQTEPSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(32085..32837)
                     /locus_tag="VUX16_000603"
     CDS             complement(32085..32837)
                     /locus_tag="VUX16_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET8123616.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(32834..33790)
                     /locus_tag="VUX16_000604"
     CDS             complement(32834..33790)
                     /locus_tag="VUX16_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET8123617.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLNCLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLNILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            complement(33780..34739)
                     /locus_tag="VUX16_000605"
     CDS             complement(33780..34739)
                     /locus_tag="VUX16_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8123618.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWVLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(35162..35863)
                     /gene="galE"
                     /locus_tag="VUX16_000606"
     CDS             complement(35162..35863)
                     /gene="galE"
                     /locus_tag="VUX16_000606"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET8123619.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNASGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            36264..37328
                     /gene="pepA"
                     /locus_tag="VUX16_000607"
     CDS             36264..37328
                     /gene="pepA"
                     /locus_tag="VUX16_000607"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET8123620.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKLDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            37350..37646
                     /locus_tag="VUX16_000608"
     CDS             37350..37646
                     /locus_tag="VUX16_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET8123621.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            38328..38771
                     /locus_tag="VUX16_000609"
     CDS             38328..38771
                     /locus_tag="VUX16_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET8123622.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            38775..39539
                     /locus_tag="VUX16_000610"
     CDS             38775..39539
                     /locus_tag="VUX16_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET8123623.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     CIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            39554..40282
                     /locus_tag="VUX16_000611"
     CDS             39554..40282
                     /locus_tag="VUX16_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123624.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            40275..41795
                     /locus_tag="VUX16_000612"
     CDS             40275..41795
                     /locus_tag="VUX16_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET8123625.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAEQVAKEFLQEQGLLKK"
     gene            42140..42946
                     /locus_tag="VUX16_000613"
                     /pseudo
     CDS             42140..42946
                     /locus_tag="VUX16_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
     gene            complement(43113..43649)
                     /locus_tag="VUX16_000614"
                     /pseudo
     CDS             complement(43113..43649)
                     /locus_tag="VUX16_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            43782..44672
                     /locus_tag="VUX16_000615"
     CDS             43782..44672
                     /locus_tag="VUX16_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET8123626.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGIFGSSAVLADSVHDLVDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINMLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            44916..45269
                     /locus_tag="VUX16_000616"
     CDS             44916..45269
                     /locus_tag="VUX16_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET8123627.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            45304..46296
                     /locus_tag="VUX16_000617"
     CDS             45304..46296
                     /locus_tag="VUX16_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET8123628.1"
                     /translation="MDLRPQIIEADDVIIRVVRACVCGSDLWRYRNPETKAGHKNSGH
                     EAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGSCDNHIGNNLGGDFQA
                     EYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHAARVANVQKGDKVVVI
                     GDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVVAERGQEGITKVREIL
                     GGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRALGSTFMQNISVAGGAA
                     SATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDERKTIKSMIVIE"
     gene            complement(46342..47349)
                     /gene="galR"
                     /locus_tag="VUX16_000618"
     CDS             complement(46342..47349)
                     /gene="galR"
                     /locus_tag="VUX16_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET8123629.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            47513..48691
                     /locus_tag="VUX16_000619"
     CDS             47513..48691
                     /locus_tag="VUX16_000619"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET8123630.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPATISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLERDYEVTGLELDALVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            48710..50191
                     /locus_tag="VUX16_000620"
     CDS             48710..50191
                     /locus_tag="VUX16_000620"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET8123631.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEHVGISLD"
     gene            50261..50665
                     /locus_tag="VUX16_000621"
     CDS             50261..50665
                     /locus_tag="VUX16_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET8123632.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            50822..51676
                     /locus_tag="VUX16_000622"
     CDS             50822..51676
                     /locus_tag="VUX16_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET8123633.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDVFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            51702..52472
                     /locus_tag="VUX16_000623"
     CDS             51702..52472
                     /locus_tag="VUX16_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET8123634.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            52459..53325
                     /locus_tag="VUX16_000624"
     CDS             52459..53325
                     /locus_tag="VUX16_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnII"
                     /protein_id="HET8123635.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(53412..54674)
                     /locus_tag="VUX16_000625"
     CDS             complement(53412..54674)
                     /locus_tag="VUX16_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET8123636.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(54674..55255)
                     /locus_tag="VUX16_000626"
     CDS             complement(54674..55255)
                     /locus_tag="VUX16_000626"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET8123637.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAEKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(55655..55750)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(56134..56262)
                     /locus_tag="VUX16_000627"
     CDS             complement(56134..56262)
                     /locus_tag="VUX16_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HET8123638.1"
                     /translation="MKANYPIYRPLTKRKFRVSDHYIYPHEFAVLDPNGYFLRFSE"
     gene            complement(56373..56516)
                     /locus_tag="VUX16_000628"
     CDS             complement(56373..56516)
                     /locus_tag="VUX16_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET8123639.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(56528..57355)
                     /gene="xth"
                     /locus_tag="VUX16_000629"
     CDS             complement(56528..57355)
                     /gene="xth"
                     /locus_tag="VUX16_000629"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET8123640.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
BASE COUNT        16751 a        10512 c        12903 g        17282 t
ORIGIN      
        1 gcggtgtagc tcagctggct agagcgtccg gttcataccc gggaggtcgg gggttcgatc
       61 cccttcgccg ctataattat cttgtcggac ctttagctca gctggttaga gctctcggct
      121 cataaccgag tggtcgtagg ttcaagtcct acaaggtcca tttgaatatt ggaggattac
      181 ccaagtccgg ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaaaag cgtgcgtggg
      241 ttcgaatccc acatcctcct tttatattaa cgcgggatgg agcagctcgg tagctcgtcg
      301 ggctcataac ccgaaggtcg taggttcaaa tcctgctccc gcaataaggc tcggtagctc
      361 agttggtaga gcaatggatt gaagctccat gtgtcggcgg ttcgattccg tctcgcgcca
      421 ttttattgat agtatttatg cgggtgtagt ttagtggtaa aactacagcc ttccaagctg
      481 ttgtcgcgag ttcgattctc gtcactcgct ttgaactttg ttcaaattac caagtttttt
      541 aacttgggcg cgtagctcag gtggttagag cgcacgcctg ataagcgtga ggtcggtggt
      601 tcgagtccac tcgtgcccat taattggaga attactcaag aggctgaaga ggacggtttg
      661 ctaaatcgtt aggtcgggta actggcgcaa gggttcgaat cccttattct ccgttttaat
      721 gagagtttgt aactctcttt tttattttta gagacaataa aacttcagat ccgtaaaact
      781 taattgaatt actaatctga agttattttt atatcgttta tattataatt gtgttatttt
      841 acttccaact attgagagaa atttcgccac tatttagcca gatttctttt ccgttatcac
      901 attgaactaa aagttttcca ttttctgaga tgtctttagc aagtcccttg tagtcttttt
      961 gctctagtgt gaaagtgact tcttttccta gaatgaatga ctgttttttg tataggtata
     1021 atagctcttc tgctggtgtt tcgaagaaag tacgccagat ttctatgatc aattcattcc
     1081 ttgttatagg agctgtagct ttaaataagc tggcagcttt ttcttttaat tcctgaggga
     1141 agtctttaat agtgaaattg atacctactc caataatgat atctgtgact aagccagttt
     1201 ctacagaggt cattgcttca gtaaggattc ctccaatttt atgattgttt agatagatat
     1261 cattgaccca ttttatgtcg atatctatta aagttaggtt cttaatggct ttgtagacag
     1321 ctccagctac aagtagtgtg taggatggta atttgtcata ggggagattt ggtttaagat
     1381 ggagtgtcat ataaatacca ccttgtggtg agtagaagga acgttgaaaa cggcctcggc
     1441 ctgctgtttg ataggaagct agatagaggg tatttgcttc atggcctaaa tcaattgctt
     1501 cttttgcatc tagttgtgtt gattttgttt cgggtttaaa gctgacttta attggaagat
     1561 tttcttctag aatctctgga agaataaggt caccattcat cagtttgtat cctctatttt
     1621 tgatactatc aatttcaatg ccttcttgtt ctagtcgctt gatagctttc caaattgatg
     1681 ttcggcttag ggatagtttt tctgcgattt tttctccgct gatatagtcg gtttctttag
     1741 ataggatttg gtagacagct tggtaggatt tcataatgtt gcctttctca ctagttggta
     1801 ttgagagtat tcttttcttg tatgacttgg agtctgatta aagtattgtt tataagcttt
     1861 cgaaaaatgg agtggatctg aaaaacctac cgagtatgca attaccttga tggactcttg
     1921 ggtattttcg agaagttgtc tagctcggtg cattcgaacg tagagtaggt attctttggg
     1981 tgataaggta ttaaattctt tgaatacgct tgataagtag cttctgtgaa cggatagttc
     2041 ttttgctaaa tcttgaattg taagtgattg aggatagtgg ctatcaatta atcgtttgca
     2101 ttcaagatag agttggtggg ttgatgaaat attctttttt ttctgattgg gagcaatagt
     2161 tcccagatga aacatcagtt catgaagttg tcccatgata tggagttgag ctaattcact
     2221 tgattttgta atctgagcga agcggacaat gtctgagatg agttttgcag tagtctgggt
     2281 atgacaagtt tcagattgga tgagatagga ttgatcagaa atttgagaaa gagcaaaata
     2341 atcaggggat ttccctccag tgattcctaa ccagtagtag gcccaaggtt ctttactatc
     2401 tgcttgataa aaggttagtt cctctggttt taatagaaag aaatctcctt cttttaaatc
     2461 aacaatttta cccttgtaat aaaattttcc ttgtccttta gtaatgtaat gtagaacgta
     2521 tgtatcacga atggctggac caaaagagta attaggtgtg cattcctcat atccataaaa
     2581 gcttagggca aggtcgattg ttccagtctg gtattctgaa aaaactaaca tgtgctacct
     2641 cctacctaac attttaccat attcttgaga catttttcta ttttggaaag cgatttcagg
     2701 tgataaaata taatcaataa agtgatgagg tgaagtaaat gggagttagg atagagaata
     2761 atctatttta tgttgagagt aaaaatctaa gtttgattat tgaaaatcga aatggctact
     2821 tacttttgaa acatttagga aagactatta agaactataa aggttccaat agtgtttatg
     2881 aacgagacca tgccttttca ggaaatccaa cggctactaa tcgaaccttt agtttagata
     2941 ctcagcgaca gatttttgga caacatggct taggagattt taggaaacca accatacagg
     3001 ttcagcatag tgtaactgaa gtaacagact ttcgatttgt agaagcaaag attttaaaag
     3061 gtcagaatgg tccacagggc ttaccttctc cacatagcat ggacgataca gagactcttg
     3121 tcttaatgtt agaagattct aaggctcaac ttagtctgac tttgtattat actactttta
     3181 ataatgatgc gactattgct agctacagta aattagataa taatagtaat caggaagttg
     3241 tcatccataa agatttttct tttatggctg attttccagc tgcagattac gaaatagtaa
     3301 ctctgcaggg tgcttatgct cgtgaaaaga ctgttagacg tcaacaggta gaacaaggaa
     3361 tcttttcgat tagctcaaac cgaggtgctt ctggtcatgc tcaaacacca gctcttctac
     3421 tatgcgaaca aggagtcaca gaggatgctg ggaatgtgtt tgctattcaa ctaatgtata
     3481 gtggcaactt tgaagctttt gttcaaaaaa atcaattgaa tgaagttcgg gtggctattg
     3541 gcattaatcc agaaaacttt tcttggaagt tagctcctga ggaatacttt gaaacaccgg
     3601 tagctttagt gacccattca gatcagggat taactggtat tagtcatgaa agtcagaatt
     3661 ttgtactgaa gcacattatg ctaagtgaat tttctaaaaa agaacgtcca attctaatca
     3721 ataactggga agctacttac tttgactttc agagagaaaa actgttagag ttagcagatg
     3781 aagctaagaa agttggcatt gaactttttg tattagatga tggttggttt ggcaatcgtt
     3841 ttgatgataa tcgtgcttta ggtgattggg ttgttaatga ggaaaaactg ggtggaagtc
     3901 tagaaagtct gatttcagct atccatgaaa gaggtttgca gtttggactt tggttagaac
     3961 ccgaaatgat ttctgtagat agtgatttgt atcgtcgaca tcctgactgg gctattcagg
     4021 ttcctgacta tgagcatact tattctcgga atcaattagt acttaatctt gccaatcctc
     4081 aggtagtaga atacttgaaa agtgtcttag atcaactcct atcttatcat gatattgatt
     4141 acattaaatg ggatatgaac cgcaatatca ctaagctagg gaatggatta acttatctag
     4201 agacacagat gcaatctcat cagtacatgc tggggcttta cgaactcgtt tcttatctga
     4261 cagagaagca cagccatatt ctctttgagt cctgctctgg tggtggtgga cgaaatgatc
     4321 ttggtatgat gcgctatttc ccacaagtct gggctagtga taatactgat gccattgcac
     4381 gtttaccaat tcaatacggt tcatcctatc tctatccaac catttctatg ggggctcatg
     4441 tgtcagcagt accgaatcat cagatgggac gaatgacacc attagaaaca cgtggccttg
     4501 tagcaatgat gggaaatttg ggctatgaac ttgatttgac aaatttatca gatgaagaga
     4561 aagctacgat tgctaatcag gtgaacttgt ataaagaatt acgaccagta gttcagttag
     4621 gacagcagta tagactaatt aatcctgata ctgtatccaa tgaagcagct gtacaattta
     4681 attacggaaa tcaaacgatt gtaacctacg ttcgcgtttt atctgttgta gagaccatgg
     4741 aaacaacttt aaaattaaaa aatttggatg aagagggact atataaatta caggaaaatg
     4801 gcgaagttta ctcaggtgca gaactaatgt atgcgggcct aactgttatc ttatcccaag
     4861 gagatttttt gagtagacag tatattttta gaagactatg ataagggtgt ataaatttat
     4921 aaaggaggct ttctaatgga atggtataaa aaaatcggac ttcttgcaac tacaggttta
     4981 gctttggttg ggctcggcgc ttgctccaac tatggtaaat ctgcggatgg cacagtgacc
     5041 atcgagtatt tcaaccagaa aaaagaaatg accaaaacct tggaagaaat cactcgtgat
     5101 tttgagaagg aaaaccctaa gatcaaggtc aaagtcgtca atgtaccaaa tgctggtgaa
     5161 gtattgaaga cacgcgttct cgcaggagat gtgcctgatg tggtcaatat ttacccacag
     5221 tccatcgaac tgcaagaatg ggcaaaagca ggtgtctttg aagatttgag caacaaagac
     5281 tacctgaaac gcgtgaaaaa tggctacgct gaaaaatatg ctgtaaacga aaaagtttac
     5341 aacgttcctt ttacagctaa tgcttatgga atttactaca acaaagataa attcgaagaa
     5401 ctgggcttga aggttcctga aacctgggat gaatttgaac agttagtcaa agatatcgtt
     5461 gctaaaggac aaacaccatt tggaattgca ggtgcagatg cttggacact caatggttac
     5521 aatcaattag cctttgcgac agcaacaggt ggaggaaaag aagcaaatca ataccttcgt
     5581 tattctcaac caaatgccat taaattgtcg gatccgatta tgaaagatga tatcaaggtc
     5641 atggacatcc ttcgcatcaa tggctctaag caaaagaact gggaaggtgc tggctatacc
     5701 gatgttatcg gagccttcgc acgtggggat gtcctcatga caccaaatgg gtcttgggcg
     5761 atcacagcga ttaatgaaca aaaaccgaac tttaagattg ggaccttcat gattccagga
     5821 aaagaaaaag gacaaagctt aaccgttggt gcgggagact tggcatggtc tatctcagcc
     5881 accaccaaac atccaaaaga agccaatgcc tttgtggaat atatgacccg tccagaagtc
     5941 atgcaaaaat actacgatgt ggacggatct ccaacagcga tcgaaggggt caaacaagca
     6001 ggagaagatt caccgcttgc tggtatgacc gaatatgcct ttacggatcg tcacttggtc
     6061 tggttgcaac aatattggac cagtgaagca gacttccata ccttgaccat gaactatgtc
     6121 ttgaccggtg ataaacaagg catggtcaat gatttgaatg ccttctttaa cccgatgaaa
     6181 gcggatgtgg attaggagta gagagactat gaaaaaagta ttacaaaaat attgggcatg
     6241 ggcttttgtg gtcatccccc tcttgttaca agcaattttc ttctatgtgc cgatgtttca
     6301 aggagccttt tacagtttta ccaactggac aggattgact tataactaca aatttgtcgg
     6361 cttaaacaac tttaagctcc tcttcatgga tccaaaattc atgaatgcga ttggctttac
     6421 cgcaatcatt acgattgcca tggtggttgg tgagattgca ctcgggatct tcattgcgcg
     6481 tgtcttgaac tctaaaatca aaggccaaac cttcttccgt gcttggttct tcttcccagc
     6541 tgttttatct ggtttgacag tggctttgat cttcaagcaa gtcttcaact acggtcttcc
     6601 agcgattggg aatgcccttc atattgaatt tctccaaacc agtcttttag ggactaagtg
     6661 gggagcaatc tttgcggctg tctttgtcct tctttggcaa ggggtggcta tgcccatcat
     6721 catcttccta gctggtttgc aatctattcc aactgagatt acagaggcag caaggattga
     6781 tggtgcgact agcaagcaag ttttctggaa cattgaattg ccttacttgc taccaagtgt
     6841 ctctatagtc tttatcctag ccctaaaagg tgggctgact gcctttgacc aagtctttgc
     6901 catgaccggt ggtggtccaa acaatgccac aacctcactt gggctcttgg tttataacta
     6961 tgcctttaaa aacaaccaat tcggttatgc caatgccatt gccgtaatct tgttcttctt
     7021 aattgtagtg atttcgatca tccaattgag agtatctaag aaatttgaaa tttaagagga
     7081 gaagcatgat gaaacaagat gaaagaaaag ccctgattgg caaatacatt ctattgattc
     7141 taggatcggt tctgatttta gtgccgctcc ttgctaccct ctttagttct ttcaaaccca
     7201 ctaaggatat tgtagataat ttctttggct ttccaaccaa cttcacatgg gacaacttta
     7261 gccgtctctt agctgatggg attggaggct attattggaa ctctgtcgtc atcactgtct
     7321 tgtctttact tgcagtaatg atctttatcc ctatggcagc ctactccatc gctcgcaata
     7381 tgagtaaaag aaaagccttt accatcatgt ataccctctt aatcctcgga atcttcgtcc
     7441 ctttccaagt catcatgatt ccgattacgg ttatgatgag taaactcggt ttggctaata
     7501 cctttggttt gatcttgctc tacttgacct atgcgattcc acagaccctc tttctctatg
     7561 ttggctatat caaaatctcg attccagaaa gtctggatga agcagcagag atcgatgggg
     7621 ctaatcaatt tacaacctat ttccgcatca tcttcccaat gatgaaaccg atgcatgcga
     7681 caaccatgat catcaatgcc ctttggttct ggaatgactt catgttgcca ctccttgtct
     7741 tgaaccggga ttccaaaatg tggactctgc ctttgttcca atacaactac gcaggccaat
     7801 atttcaacga ctacggacca agctttgcct cttacgtggt cggcattatc agtatcacca
     7861 ttgtctatct cttcttccaa cgccatatca tttcaggaat gagcaacggg gcagtgaagt
     7921 aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc tcaaaacact
     7981 gttttgaggt tgtggatgaa actgacgaag tcagtaacca tacctacggt aaggcaacgc
     8041 tgacgtggtt tgaatttgat tttcgaatag tataagaaga gctcatggaa tctatagtct
     8101 ttgacacaga ggaagagttc agcttgttga taattctatg tagaaaacaa gaaagtagta
     8161 ctttgtttat cacagtctat attagtacga gtttgatgat aaatagagat ttaaaatgaa
     8221 ttttatttat gaagccagat catatgagac ttggcttcaa ttagaaaaag gagagtaatg
     8281 atgccaattc aaaataaaac catgttgatt acctattctg atagccttgg aaataatctt
     8341 aaagacttat atgataattt ggaagagcat tttggagatg ctattggagg agttcacctt
     8401 ttaccatttt tcccatcaac aggtgatcgt ggatttgcgc cagttgacta cgacgaagtg
     8461 gactcagctt ttggtgattg ggaggatgtt aagcgtttag gtgagagata ttatcttatg
     8521 tttgatttta tgattaatca tatttctcgt caatccaagt attataagga ctatcaagaa
     8581 aaacatgaag ccagtgaatt taaagatctc tttttaaact gggataagtt ttggccagaa
     8641 aaccgtccga cacagtctga tgtagattta atttacaagc gtaaggatcg tgcaccaaag
     8701 caagagattg tgtttgaaga tggttcagtg gaacatttgt ggaatacctt tggtgaggag
     8761 cagattgatc ttgatgtgac caaagaagta actatggaat ttatccgtaa gaccattcag
     8821 cacttggcaa gtaatgggtg tgatttgatt cgtctagatg cctttgctta tgcagtgaag
     8881 aaattggata ctaatgattt ctttgtggaa ccagatattt gggatttatt ggacaaagtt
     8941 cgagatatcg ctgctgagta tgggacagag cttttacctg agattcatga acactattcg
     9001 attcagttta aaatagcaga ccatgattac tatgtttatg attttgctct tccaatggtg
     9061 acactttata ctctttacag ttccagaaca gagcgtttgg ctaagtggtt aaagatgagc
     9121 ccgatgaagc aatttacgac gctagatacc catgatggga ttggagtagt agatgtcaag
     9181 gatatcctga ccgatgagga gattgactat gcttcaaatg aactttataa ggttggagcc
     9241 aatgtcaaac gtaagtactc tagtgccgag tataacaact tagatatcta ccaaatcaat
     9301 tcaacctact attcagcgct tggagatgat gatgtcaagt attttctcgc tcgtctaatt
     9361 caagcttttg ccccaggtat tcctcaggtt tactatgtgg gtctattagc aggcaagaat
     9421 gacttgaaat tattagaaga aactaaagaa ggtcgaaata ttaatcgtca ttactatagc
     9481 aacgaggaaa tagcaaaaga agtgcaacga cctgttgtga aggcccttct caatctattt
     9541 tctttccgta accgttcaga agcctttgat ctagaaggga ctactgagat agagacacca
     9601 acagctcaca gcattgtaat caaacgtcaa aataaagata agtccgtaac agcagtatca
     9661 gaaattgatt tgcaaaatca gacttatcgg gtaattgaga atggagttga agtaacattt
     9721 tgaagccttg atatggtgga taaaataggg tttttatttt ggaaaacgtt tcctttgttt
     9781 tcaaattgct aaaaaagtgg tacaatatag gatagcttac tattatctga atcagctgat
     9841 ttggagagaa aggattcatt ttgaaatcaa taggctttat tgaaaagctg aaggggttgt
     9901 ctagtaaaga gctgatttta ttgggaatta tcctgagtat ctttttaccc ttttatcttt
     9961 ttgtagttgt actctgttta tatattatca gtttgatttt tacaggagac atgaaaagta
    10021 ttcttcagaa aatgggggag catccgatgc tgcttctttt tcttagctat agtactgtta
    10081 tatccattct tgcacaaaat tggatgggtc ttgtggcttc agtaggaatg tttctattta
    10141 ctattttctt tttgcactat cagtcgattt tatcccataa attctttcga ttgattttgc
    10201 agttcgtctt gtttggtagt gtcttgtcag ctgcttttgc cagtttagaa catttccaaa
    10261 ttgtgaagaa atttaactat gcttttcttt cacccaatat gcaggtgtgg catcagaacc
    10321 gggcagaagt gaccttcttt aatcctaatt attatggaat tatttgttgt ttctgtatta
    10381 tgattgcttt ctatctgttt acaacgacca agttgaattg gttgaaagta ttctgtgtga
    10441 ttgcaggctt tgttaatctc tttggtttga actttactca aaatcgaact gcctttcctg
    10501 ctattatcgc tggagcaatt atctatctct ttacgactat taaaaactgg aaggcctttt
    10561 ggcttagtat tggggtcttc gcgattggtt tgagtttcct cttttctagt gatttgggag
    10621 ttcgaatggg tactttagac tcttctatgg aagaacgcat ttctatctgg gatgctggga
    10681 tggccttgtt taagcaaaat cctttttggg gtgaagggcc attgacctat atgcactctt
    10741 atcctcggat acatgctcct tatcatgaac atgcccacag tctttatatt gatacgattc
    10801 tgagttacgg aattgtgggt accattttat tagttttgtc ttctgttgct cctgttcgct
    10861 tgatgatgga tatgagtcag gagtcgggga aacgtccgat tatcggcctt tatctatctt
    10921 tccttacagt ggttgctgtg cacggaattt ttgacttggc tctcttctgg attcagtcag
    10981 gctttatttt cttgctagtt atgtgcagta ttccattgga gcatcgaatg ttggtatcgg
    11041 acatgacgga ttaagtttta taagtttgaa atcttctacc ttgggtagga gattttttta
    11101 tacgatgggc atgtcgtgca tctgaggtgt aagtcctctg tagggatcca ctaccggtga
    11161 atacaatagc gctccccaag cctgactatc gtgaggtagc ggattaaaat ggtctgggga
    11221 tagatcgttt taagtctgac gcaggaaata agaattgtca gagaaagcaa tagtgaaatc
    11281 gtaggctatg aatagaaacg tgatagcgag gagcatatag tggataaggt agcgagaaat
    11341 tttaaagtat aaaagatagt cttaatctat atatgtaaat cacaaaagta attgaattcg
    11401 gaataaggtt ggtgtgaaaa gacatagtaa actgaatctt gaatactaga atgatacttc
    11461 tacaatattg ttataattta atttgaattc caaaatcaca ttgttccgtc cgtatttcat
    11521 tttactgtat gtcttcctaa actccaaagt ttctgcgtca aatttcctat tttcactgta
    11581 gtctttgaca cttcgaacga caatttgaat catatattca aaaaaaaatg aaaaatttgt
    11641 gccaacaagc ctaaatattc tgaaaatttg tttgattttt aatggataat gtgatataat
    11701 ggttgtcaat ctataattca cataaacaga ggagtagaaa atgaaaaaaa atcgtgtatt
    11761 tgctacagca ggtcttgttt tattagcagc aggtgtactt gcagcatgca gttcttcaaa
    11821 atcatctgat tcatcagccc ctaaagctta tggctatgtt tatacagcag acccagaaac
    11881 cttggactac ctgatttcaa gtaaaaatag tacaacagta gtgacttcaa atgggattga
    11941 tggtttattc actaacgata attacggtaa tcttgctcct gcagttgcag aggattggga
    12001 agtctctaag gatggtttga cctacactta taagattcgt aaaggggtta aatggtttac
    12061 ctctgatgga gaagaatatg cagaggtgac ggctaaagat ttcgtgaacg gtttaaaaca
    12121 cgcagcagat aaaaaatcag aagctatgta tttagctgaa aattcggtta aaggcttggc
    12181 agattatcta tcaggaactt caacagattt ttcaacagtt ggtgtcaagg cggttgatga
    12241 ttatacgtta caatacactt tgaaccagcc tgaaccgttc tggaactcta agttgaccta
    12301 ttctattttc tggcctctga atgaagaatt cgaaacatca aaaggaagcg attttgctaa
    12361 accaacagat ccgacatcct tgctttataa tggtccattc ttgttgaaag ggttgactgc
    12421 aaaatcttct gtagagtttg taaaaaatga gcaatattgg gataaagaaa atgtccacct
    12481 agatactatc aatctagctt actatgatgg atcagatcag gagtcgctag agcgtaactt
    12541 cactagtgga gcttatagtt atgcccgtct ttaccctacc agctccaact attctaaggt
    12601 tgcagaagaa tacaaggaca atatctatta cacacaatca ggctctggga ttgctggtct
    12661 gggtgtgaat attgatcgcc aaagttacaa ctatacttct aaaactacag attcagagaa
    12721 agtagctact aagaaggcat tgcttaacaa agatttccgt caagccttga attttgctct
    12781 tgatcgctca gcttactcag ctcaaatcaa tggtaaagat ggagcagctt tagcagttcg
    12841 taatttattt gtaaaaccag actttgtttc agctggtgag aagacctttg gtgatttagt
    12901 cgctgctcaa cttcctgctt atggtgatga gtggaaaggt gtgaatttag ctgatgggca
    12961 ggatggttta ttcaatgctg acaaggccaa ggcagagttt gcgaaagcta agaaagcttt
    13021 agaagcagac ggcgttcagt ttcctattca tctggacgtt ccagtagacc aagcatcaaa
    13081 aaactacata tctcgtattc agtcctttaa acaatctgta gaaacagttc ttggtgttga
    13141 aaatgtcgtt gttgatattc aacaaatgac aagtgatgaa ttccttaata ttacttacta
    13201 tgctgccaat gcttcatctg aggattggga tgtatcagga ggagtttcat ggggtccaga
    13261 ctatcaagac ccatctactt acctggatat tttaaaaaca actagcagtg aaactacaaa
    13321 aacatattta ggatttgata atccaaatag cccttcagta gttcaagttg gtttgaaaga
    13381 atacgataaa ttagttgatg aagctgccag agagacaagc gacttgaatg tccgttatga
    13441 aaaatatgca gcggctcaag catggttgac agatagttca ctctttattc ctgctatggc
    13501 ttcttctggt gcagcaccag tgctttcacg aattgttcca tttactggag cttctgcgca
    13561 aacaggctct aaggggtcag atgtttactt caaatatttg aaattacaag ataaagtggt
    13621 gactaaggaa gagtatgaaa aagctcgtga aaaatggttg aaagaaaaag ctgaatcaaa
    13681 tgagaaagct caaaaagaat tggcaagtca tgtgaagtaa ataatttcta atagaacttt
    13741 ctctccatga ggagaaggtt cttttgggat ttttaaagga aataatatga aaaaatatat
    13801 ttttatgcgt gttttgcggt cattggtttc gattttctta gtaacgactt tgacctacac
    13861 gattatctat accttggttc ctcgaaaatt gattttcaag caggatccta actataataa
    13921 aattgcgaca acggctgata aacgtgataa ctatgaaaat actgtgtttg agcgtatggg
    13981 ctacattgag tattacgata ctaaagagtt gcaagaaaag gcaagtagca tggattcttc
    14041 tgtaacagta gaagcaaatg cgaccaataa agctatttat gaaaagtaca tcaatcaatt
    14101 aggtcatggt tggactttgg gagaatttac tgaaagtggt caattctatg ctactcgtga
    14161 aattccaatt tttgaacgtg tttttcactt ctatgctaac ttgattgaca ttgaccatac
    14221 aaataaaatc caagaccctg aaaatccaga cttgaaacgc taccttcgtt ttgaaaatga
    14281 tccagctatc ggatggtcat tggtcggttc aggaactaaa cataaatatc tcttgtactt
    14341 taacagtcag ttcccatttg ttcatcaaaa ctttgtgaac ttgaatttag gtgactctta
    14401 cccaacctat gctaatacac cagttcttca ggttattact caaggtcaag gacaaaccaa
    14461 aactgcccaa gttcagttcc caacaggtaa gaaaacgtct tctgtaaata tttactcaag
    14521 aacctacaag tcacctagtc aggctgactc tcgtgaagta gctagctatg ggaaagatga
    14581 tccttataca gcgactgaaa gtaattacca atatccatct atgattgtca gctctgctat
    14641 tactggtttg attggtttgg ttcttgccta tgctcttgcc gtgccacttg gttcagccat
    14701 ggctcgtttc aagaacactt ggattgatag cctctcaaca gggactttga ccttcttgct
    14761 tgctcttcca acgattgcct tggtttacat cgttcgattg attggatcat ctattgccct
    14821 tccagattca ttccctatct tgggagctgg agattggcgt tcttacgttt taccagcagt
    14881 catccttggt ttgttgggtg ctcctgttac agccatttgg attcgtcgtt acatgattga
    14941 cttgcaatct caagactttg ttcgtttcgc tcgtgcaaaa ggtttgtctg aaaaagaaat
    15001 ttcaaacaaa cacatcttta aaaatgccat ggttccgctg gtttcaggaa ttcctggtgc
    15061 cattattggg gttatcggtg gtgcaaccct tactgaaaca gtcttcgcct tcccaggtat
    15121 gggtaaaatg ttgattgact ctgtaaaagc atctaataac tctatggtcg ttggtcttgt
    15181 cttcatcttt acatgtattt ctatcttctc acgtcttttg ggagatattt ggatgactat
    15241 tattgaccca cgtattaaat tgactgagaa aggaggcaaa taatgtctac aatcgataaa
    15301 gaaaaatttc agtttgtaaa acgtgacgat tttgcctctg aaactattga tgcgccagca
    15361 tattcttact ggaaatcagt gtttaaacaa tttatgaaga aaaaatcaac tgtagtcatg
    15421 ttgggaatct tggtagccat cattttgata agtttcatct acccaatgtt ttctaagttt
    15481 gatttcaatg atgtcagcaa ggtaaacgac tttagtgttc gttatatcaa gccaaatgcg
    15541 gagcattggt tcggtactga cagtaacggt aaatcgctct ttgacggtgt ctggttcgga
    15601 gctcgtaact ccatcctcat ttctgtgatt gcgacagtga ttaacttggt tatcggtgtt
    15661 tttgtcggtg gtatttgggg tatttcaaaa tcagttgacc gtgtcatgat ggaagtttac
    15721 aacgtcatct caaacatccc acctcttttg attgttattg tcttgactta ctcaatcgga
    15781 gctggattct ggaatctgat ttttgccatg agcgtaacaa catggattgg tattgccttc
    15841 atgatccgtg tgcaaatctt gcgctatcgt gacttggaat acaacttggc gtcacgtact
    15901 ttgggaacac caaccttgaa gattgttgcc aaaaatatca tgcctcaatt ggtatctgtt
    15961 attgtgacaa ccatgactca aatgcttcca agctttatct catacgaagc cttcttgtct
    16021 ttcttcggtc ttggattacc gattacagtg cccagtttgg gtcgtttgat ttcggattat
    16081 tcacaaaacg taacaaccaa tgcttacttg ttctggattc cattgacaac ccttgtcttg
    16141 gtatccttgt cccttttcgt agttggtcaa aacttagcgg atgctagtga tccacgtaca
    16201 catagatagg agtagaaatg acaaaagaaa aaaatgtaat tttgactgct cgcgatattg
    16261 tcgtggaatt tgacgttcgt gacaaagtat tgacagccat tcgcggcgtt tcccttgaac
    16321 tagtcgaagg agaagtatta gccttggtag gtgagtcagg atcaggtaaa tctgttttga
    16381 caaagacctt cacaggtatg ctcgaagaaa atggtcgcat tgctcaaggt agtattgact
    16441 accgtggtca ggacttgaca gctttatctt ctcacaagga ttgggaacaa attcgtggtg
    16501 ctaagattgc gactatcttc caggacccaa tgactagttt ggaccccatt aaaacaattg
    16561 gtagtcagat tacagaagtt attgtaaaac accaaggaaa aacagctaaa gaagcgaaag
    16621 aattggccat tgactacatg aataaggttg gcattccaga tgcagataga cgttttaatg
    16681 aatacccatt ccaatattct ggaggaatgc gtcaacgtat cgttattgcg attgcccttg
    16741 cctgccgacc tgatgtcttg atctgtgatg agccaacaac tgccttggat gtaactattc
    16801 aagctcagat tattgatttg ctaaaatctt tacaaaacga gtatcatttc acaacaatct
    16861 ttattaccca cgaccttggt gtggtggcaa gtattgcgga taaggtagcg gttatgtatg
    16921 caggagaaat cgttgagtat ggaacggttg aggaagtctt ctatgaccct cgccatccat
    16981 atacatggag tctcttgtct agcttgcctc agcttgctga tgataaaggg gatctttact
    17041 caatcccagg aacacctccg tcactttata ctgacctgaa aggggatgct tttgccttgc
    17101 gttctgacta cgcaatgcag attgacttcg aacaaaaagc tcctcaattc tcagtatcag
    17161 agacacattg ggctaaaact tggcttcttc atgaggatgc tccaaaagta gaaaaaccag
    17221 ctgtgattgc aaatctccat gataagatct gtgaaaaaat gggatttgcc catctggctg
    17281 actaggagga aggaaatgtc tgaaaaatta gtagaaatca aagatttaga aatttccttc
    17341 ggtgaaggaa gtaagaagtt tgtcgcggtt aaaaatgcta acttctttat caacaaggga
    17401 gaaactttct cgcttgtagg tgagtccggt agtgggaaaa caactattgg tcgtgctatc
    17461 atcggtctaa atgatacaag taatggagat atcatttttg atggtcaaaa gattaatggt
    17521 aagaaatcgc gtgaacaagc tgcggaattg attcgtcgaa tccagatgat tttccaagac
    17581 cctgccgcaa gtttgaatga acgtgcgact gttgattata ttatttctga aggtctttac
    17641 aatcaccgtt tatttaagga tgaagaagaa cgtaaagaga aagttcaaaa tattatccgt
    17701 gaagtaggtc ttcttgctga gcacttgact cgttaccctc atgaattctc aggcggtcaa
    17761 cgtcaacgta tcggtattgc ccgtgccttg gtcatgcaac cagactttgt tattgcagat
    17821 gagccaattt cagccttgga cgtttctgta cgtgcccaag tcttgaactt gctcaaaaaa
    17881 ttccaaaaag agctcggcct gacctatctc ttcatcgccc atgacttgtc ggttgttcgc
    17941 tttatttcag atcgtatcgc agttatttac aagggtgtta ttgtagaggt tgcagaaaca
    18001 gaagaattgt ttaacaatcc aattcaccca tatactcaag ccttgctttc agcggtacca
    18061 atcccagatc caatcttgga acgtaagaag gtcttgaagg tttacgatcc aagtcaacac
    18121 gactatgaga ctgataagcc atctatggta gaaatccgtc caggtcacta tgtttgggcg
    18181 aaccaagccg aattggcacg ttatcaaaaa ggactaaact agtaatggtt ttataatttc
    18241 catgtcaatt tttatggaaa ttaggctctt tgtcaactgt agtgggttga agtcagctaa
    18301 gctcgagaaa ggacaaattt cgtcctttct tttttgatgt tcaaagcgat aaaaatccgt
    18361 tttctgaagt tttcaaagtt tcgaaaacca aaggcattgc gcttgataag tttgatgaga
    18421 ttattggtcg cttccagttt ggcattagaa tagtgtagtt gaagggcgtt gacaatcttt
    18481 tctttatctt tgaggaaggt tttaaagaca gtctgaaaaa gaggatgaac ctgctttaga
    18541 ttgtcctcaa taagcccgaa aaatttctct ggttccttat tctggaagtg aaaaagcaag
    18601 agctgataga gctgatagtg gtgtttcaag tcttctgaat agctcaaaag cttgtttaaa
    18661 atctctttat tggttaagtg catacgaaaa gtaggacgat aaaaacgttt atcgctcaat
    18721 ttacggctat cctgttgaat gagtttccag tagcgcttga tagccttgta ttcatgggat
    18781 tttcgatgaa actgattcat gatttggaca cgcacacgac tcatagcacg gctaagatgt
    18841 tggataatat ggaaacgatc tagaacgatt ttagcacacg gaaaaatctg tttagccaag
    18901 tcatagtaag gactaaacat atccatcgta atgattttca cttgacaacg aacggctcta
    18961 tcgtagcgaa gaaagtgatt tcggatgaca gcttgtgttc tgccttcaag aacagtgata
    19021 atattaagat tatcaaaatc ttgcgcaatg aaactcatct ttcccttagt gaaggcatac
    19081 tcatcccaag acataatctt tggaagccga gaaaaatcat gctcaaagtg aaagtcattg
    19141 agcttgcgaa tgacagttga agttgaaatg gaaagctgat gggcaatatc agtcatagac
    19201 attttttcaa ttaacttttg agcaattttt tggttgatga tacgagggat ttggtgattt
    19261 ttctttacca ggggagtctc agcaaccatc atttttgaac agtgatagca cttgaaacgg
    19321 cgttttctaa ggagaattct agaaggcata ccagttgttt cgaggtaagg gatcttagac
    19381 ggtttttgaa agtcatattt cttcattaga cttccacaat cagggcaaga tggagcctca
    19441 taatccagct tagcgataat ttctttgtgg gtatccatat tgatgatatc tagaatcttg
    19501 atgtttgggt ctttaatatc gagcagtttt gtgataaaat gtaattgttc catatgaatc
    19561 tttctaatga tggttttgtc gcttttcatt ataggtcata tgggactttt tttctataac
    19621 aaaataggct ccataatatc tataagggat ttacccacta caaatattat agagccgaaa
    19681 aaggctgaga tctggtgtct cagtctttta tttcttgcgt tttgcaaaat ctacaaatct
    19741 aaatttctct aacttatggc gactttcggt aaactgaaat tggcgtccgt cttggagata
    19801 gacttttgat ttaatcgaaa cgacataagg gtctttgcca atgtccatga gaatcttgtc
    19861 tcggtcgctt gagtggtcaa tggtgatttc cttctgagca taatcaataa ggagtttgag
    19921 gccattttct atataagaat agatagactg ctcagcaatt tggcgagtga gatttgggat
    19981 gagttccata tccagatagt ccgtatccag aacggatacc agatcatcca ccacacgctg
    20041 gcggcccacc ttccaaacca tccgaaactc taggaaaccg gttatcagtg aggatttttt
    20101 atcaataata atcttgtcca gactgaccac gttggtttta gagcgcagtc caagttcttt
    20161 aactagttct tggtagctgg ttaggttgga tacagggaaa ttgacggttt cttctttgac
    20221 gacttgagaa ccttgccctc ttatcttttt gatcaatcct tcctcttgga ggagagacag
    20281 ggcctttcgg acggtatcac gactcacttg atattgctcc ataaggtcgt gctcgctagg
    20341 aaggaaatct ccgacagcgt aagtctcgtt ttgaatggtt tcttggattt gcttaaataa
    20401 ttgttggtat ttcttcattt tgcctgctta aataggtttt tagtctagtt taatgaacac
    20461 ctgtatctat tttaccatac aagtgctaga aaatttacaa aaaaacaccc tttttatacc
    20521 aaacaagttg cagacaagtt tggtatcgtt tacaatatac ttatcaaatc aaacttgctt
    20581 tgacaagtat aaggagaatc aaatgggaaa atttgaacaa gaagccaaag atctgcttca
    20641 ggcaatcgga ggcaaagaaa atgtgactgc cgtaactcac tgtgcgacac ggatgcggtt
    20701 tgttttagga gatgataaga aggctaatgt taaagctatc gagtcaattc cagctgttaa
    20761 aggaaccttt acaaatgcag gtcaatttca ggtaatcatt ggaaatgacg tgcccatctt
    20821 ttataatgat tttacagccg tttcaggtat tgagggtgtt tccaaagaag cagccaagtc
    20881 tgcagctaag agtaatcaaa acgtggtcca acgtgttatg accactctgg cggaaatctt
    20941 tactccgatt attccagcct tgattgttgg tggattgatc ctcggtttcc gtaatgtctt
    21001 ggaaggtgtc cattggtcga tgttggatgg caagaccatc acagaatcct ctcagttttg
    21061 ggcaggggtt aatcacttcc tctggttgcc tggtgaagct atcttccagt tcttaccagt
    21121 agggattact tggtctgttt ctcgtaagat gggaaccagc caaattttgg gaattgttct
    21181 cggaatctgt ttggtatcgc ctcagttgct caatgcctat gcggttgctt caacgccagc
    21241 agctgatatc gcggcaaact gggtttggaa ttttggctat tttactatta atcgtatcgg
    21301 ttaccaagcc caagttatcc cagccttgct tgcaggtttg agtctgtctt atcttgaaat
    21361 cttctggcgc aagcatatcc cagaagtcat ttctatgatt tttgtacctt tcttgtcatt
    21421 gattccagcc ttgattttgg ctcatactgt tttgggacca atcggttgga caattggaca
    21481 aggactttca tcagttgtct tggcaggttt aactggtcca gttaaatggc tcttcggtgc
    21541 aatttttggt gccctctacg ctccatttgt catcacaggt ctgcaccata tgaccaatgc
    21601 cattgataca caattgattg cggatgctgg tggcactgcc ctatggccaa tgattgctct
    21661 ttctaatatt gctcaaggct cagccgtgtt tgcctattat ttcatgcatc gccatgatga
    21721 gcgtgaggct caggtttcac ttcctgcaac catttcagcc tatctcggtg ttacagaacc
    21781 agctcttttt ggggttaacg taaaatatat ttatccattt gttgctggga tgactggttc
    21841 agcccttgca ggcatgttat ccgttacttt taatgtaact gcggcttcta ttggtatcgg
    21901 tggtttgcca ggtattctct ctattcaacc tcaatacatg ctgccatttg caggaactat
    21961 gctagttgcg attgttgttc caatgctctt gactttcttc tttcgcaagg ctggtctctt
    22021 cacaaaaata gagggcgata cgaacttgca ggcagaattc gttgctcaag aagaagcaga
    22081 atttgtgagc catgaaccag tagaacttac ttcggtagaa attatcagcc cactaactgg
    22141 ccaagtgaaa gaattgagtc aagcgacgga tcctgttttt gcatcaggtg tcatggggca
    22201 aggtctggtc attgaaccaa gccaaggtga gttgacctct ccagttaatg gaacagtgac
    22261 ggttcttttc cctaccaagc atgccatcgg cattgtctct gacgagggag ttgaattgct
    22321 catccacatc ggtatggata cagtaggtct tgatggcaaa ggttttgaaa gtcttgtagt
    22381 ccaaggagat cacgttatag ttggccagca actgattcgt tttgatatgg atgtcattaa
    22441 ggctgcaggt ctggtgacag aaactcctgt tatcatcacc aaccaagatg cttatacagc
    22501 gactattact ggaacttatc cgacaacgat ccaagctgga gcatctctca tggtcgctac
    22561 acgaatctaa tactcttcga aaatctcttc aaaccacgtc agctctatct gcaacctcaa
    22621 aatagtgttt tgagcaacct gtggctagct tcctagtttg ttctttgatt ttcattgagt
    22681 ataattgaaa tagcacaaat agggacggaa gactgcttcc tcccttttat cagaaaagga
    22741 gaaacagatg acacttgata aaggaaaagt agtctatcaa atctatccaa aatcttacaa
    22801 agacaccact gaaaacggta ttggggattt ccgtgggatt atcgaaaaaa ttccctattt
    22861 agccaaacta ggtgtggata tggtctggct caatccattc tatccaagcc ctcaacggga
    22921 taatggttac gatatttcag attatatggc agtggatcct ctttttggtg atatggctga
    22981 ttttgaggaa atggtgtgtg tcggtaaaga gcacaagatt gactttatgc tggacatggt
    23041 acttaatcat tgttcgacag agcatgaatg gtttcagaaa gccctagctg gtgataagta
    23101 ttatcaagac tttttcttca tccaagacca accaacagat tggcagtcta agtttggtgg
    23161 ttctgcatgg gcgcctttcg gggatactgg gaaatactat cttcacctat ttgatgagac
    23221 ccaggctgac cttaactggc gcaatcccaa tgtccgtaag gagcttttca aggttgttaa
    23281 tttctggcgc gacaagggtg tcaaaggttt tcgatttgat gtgatcaatt tgatcggtaa
    23341 ggacgaggtt tcagtggact gtcctgaaaa tgaagggaag ccagcttata cagacaaacc
    23401 catcgttcat aactatttgc gtatgatgaa ccaagccact tttggatctg acgatagctt
    23461 tatgacagtt ggggaaatgt cttctaccac catggaaaac tgtgtccttt attcgtcgcc
    23521 tgatcgtcag gaattatcca tgacctttaa ttttcatcac ctcaaggtgg actataagga
    23581 tggacaaaag tggaccttgg ctccctttga ttttgaagag ttgaagagtc tttaccatag
    23641 ttggggtaag gaaatgagtg ataaagacgg ttggagtgcc ctcttttgga acaatcacga
    23701 tcaaccacgt gccttgaacc gttttgtcga tattcaaaac ttccgcaagg aaggagccac
    23761 catgctagca gccagcattc acctgtcacg tgggacacct tatatctaca tgggtgagga
    23821 aatcgggatg attgacccag actatgattc tatggctgat tatgtggatg tcgaatcgct
    23881 taatgcctat cagatgctct tagaagaagg aaagagtcag caagaggcct tccagattat
    23941 tcaagctaag tcgcgtgata attcacgtat tcccatgcag tgggatactt ctgaaaatgc
    24001 aggattttca acaggcactc catggttgaa agtcggtaaa tcctataaag atatcaatgt
    24061 agaaaatgaa atcaaaggtc tgattttcac cttctatcaa gacttgattc gactgcgtaa
    24121 ggaaatgcca atcatttcag aaggaaatta caaaccagcc tttgaagata gcaaacaagt
    24181 ctacgctttt gaacgccagt ttgaggatca aaagttacta gtgctcaata acttttatgc
    24241 caaagaagtg gaaatcgact tgccagcagt ctaccaaaat ggacagattt tgatttcaaa
    24301 ctatgaagat gcagaagtgt ctgagaaaat tctactcaaa ccctatcaaa cactggctat
    24361 ttatgtaaat taatactctt cgaaaatctc ttcaaaccgt gtcagtttta tctgtaacct
    24421 caaagcggtg ctttgagcaa cctgtggcta gcttcctagt ttgctctttg attttcattg
    24481 agtataaact tagcaaggag acctcttttt cagaaaagca gggttctttt tgctgtctat
    24541 tccatccttg aaagtgtaga acaaactggt cagggtggct agtttgtggt ataatgaaag
    24601 ggattcaaaa agaaacagga gaaaaatgat ggatttactt ttagcaattg tattgattgt
    24661 gctagctttt ctaggaggag ctcttggagg aatgtacttg gttcgtaagc aaatcgaaaa
    24721 agaatttgct gacaacccac gtttgaatgc tgaagcagtt cgtactcttt tgagtgcaaa
    24781 tggtcaaaaa ccaagcgaag ctaaggtaca acaagtttac caccaaatca tccgccaaca
    24841 aaaggcagcc cttgctaaca ataaaaagaa aaaataaata aggaaaagtc tgggatgaaa
    24901 gttccagact tctcactatg ttggttatgg tttagggatg agactttttc cttgcattct
    24961 attgatattt gattatgatt aagagagagg tagttgacat tctatcaagc tgtcggtcag
    25021 ttcgttcagt acaaggaatc ataatgaacg atcaatcaga aaaaagacta gaaagaagac
    25081 tgtatggata atcgaccaat tggttttttg gattcgggtg tcgggggctt gaccgttgtg
    25141 cgcgagctca tgcgccagct tccccatgaa gaaatcgtct atattggaga ttcggcgcgg
    25201 gcgccctatg gcccccgtcc tgctgagcaa attcgtgaat atacttggca gctggtcaac
    25261 tttctcttga ccaaggatgt caaaatgatt gtcattgctt gtaacactgc gactgcggtc
    25321 gtctgggaag aaatcaaggc tcaactagat attcctgtct tgggtgtaat tttgccagga
    25381 gcttcggcag ccatcaagtc cagtcaaggt gggaaaatcg gagtgattgg aacgcccatg
    25441 acggtacaat cagacatata ccgtcagaaa atccatgatc tggatcccga cttacaggtg
    25501 gagagcttgg cctgtcccaa gtttgctccc ttggttgagt caggtgccct gtcaaccagt
    25561 gttaccaaga aggtggtcta tgaaaccctg cgtcccttgg ttggaaaggt ggatagcctg
    25621 attttgggct gtactcatta tccactcctt cgccctatta tccaaaatgt gatggggcca
    25681 aaggttcagc tcatcgatag tggggcagag tgcgtacggg atatctcagt cttactcaat
    25741 tattttgaaa tcaatcgtgg tcgcgatgct ggaccactcc atcaccgttt ttacacaaca
    25801 gccagtagcc aaagttttgc acaaattggt gaagaatggc tggaaaaaga gattcatgtg
    25861 gagcatgtag aattatgaca aataaaattt atgaatataa ggatgaccag gactggtatg
    25921 ttgggtctta tagtattttt ggtggcgtta acagtttgag cgactataag acagattttc
    25981 ctctgtttga attctccaaa atatttggag atgaagagta tggtttcccg ctttcagtta
    26041 ctgttttacg ctatggttct acctaccgtt tgttctcctt tgtggtagac atgcttaatc
    26101 aagaaatggg acgaaacttg gaagttattc aacgtcatgg ggccctgctc ttggttgaaa
    26161 atgggcaact cttgtatgta gaattgccta aagaaggggt caatgttcat gatttctttg
    26221 agacaagcaa ggtcagagaa accttgttga ttgcgactcg taacgaaggt aaaaccaagg
    26281 aattccgagc tatctttgat aagttaggct acgatgtgga aaatcttaat gactaccctg
    26341 acctgcctga agtagcagaa acaggtatga cctttgaaga aaatgcccgc cttaaggcag
    26401 aaaccatttc tcaattaacg ggcaagatgg ttttggcaga tgattctggt ctcaaagtcg
    26461 atgtccttgg tggcttacca ggcgtctggt cagctcgttt cgcaggtgtg ggagcaactg
    26521 accgtgaaaa taatgccaaa ctcttgcacg aattggccat ggtctttgaa ctcaaggacc
    26581 gctcggctca gttccacaca accctagtcg tagccagccc aaataaggaa agtttagttg
    26641 ttgaagcaga ctggtcaggt tatattaact ttgaacctaa gggtgaaaat ggctttggct
    26701 atgatcccct cttccttgta ggagagacag gtgagtcatc agctgaatta accctggaag
    26761 aaaaaaatag tcaatctcac cgtgccttag ccgttaagaa acttttggag gtatttccat
    26821 catggcaaag caaaccatca ttgtaatgag cgattcccat ggcgatagct tgattgtgga
    26881 agaagtccgt gatcgctatg tgggcaaagt cgatgccgtt tttcataacg gcgattctga
    26941 actacgtccg gattctccac tttgggaggg catccgcgtt gttaaaggga acatggactt
    27001 ctacgccggc tacccagaac gtctggtgac tgagcttggt tcgaccaaga ttatccaaac
    27061 tcatggtcac ttgtttgaca tcaatttcaa ctttcaaaag ttggactact gggctcagga
    27121 ggaagaggcc gctatctgcc tctatggtca cttgcatgtg ccaagtgctt ggttggaagg
    27181 caagatcctc tttctaaatc caggttctat cagtcaacca cgaggtacca tcagagaatg
    27241 tctctatgct cgtgtggaga ttgatgatag ttacttcaaa gtggactttt tgacacgaga
    27301 tcacgaggtg tatccaggtt tgtccaagga gtttagccga tgattgccaa ggagtttgag
    27361 actttcttgt tggggcagga ggaaactttt ttgacccctg ctaaaaatct agctgtgttg
    27421 attgataccc acaatgcgga tcatgcgacc ctcttgctca gtcagatgac ctatacccgt
    27481 gttcccgttg tgacagatga aaaacagttt gttgggacga ttggactcag agatattatg
    27541 gcttatcaga tggagcatga cttgagccaa gaaatcatgg cggatacgga tatcgttcat
    27601 atgacaaaaa cggacgtagc ggttgtttcg cctgatttca ccattacgga ggtcttgcac
    27661 aagctagtag atgagtcctt cttaccggtt gtggatacag agggtatttt ccaagggatt
    27721 attacgcgca agtccatcct caaggccgtt aatgccctct tgcatgattt tagtaaggaa
    27781 tatgagattc gatgccaatg agagacagga tttcagcctt tttagaggaa aagcagggct
    27841 tgtctgtcaa ttccaagcag tcctataagt atgatttgga gcaattttta gacatggtag
    27901 gtgagcggat ttctgagacc agtctcaaga tttaccaagc ccagctagcc aatctaaaaa
    27961 tcagcgccca gaagcgaaag atttcggcct gtaaccaatt tctctacttt ctctatcaaa
    28021 aaggagaggt ggacagcttt taccgcttgg aattagccaa acaagctgaa aagaagacgg
    28081 aaaagccaga gattctatac ctagactctt tttggcagga aagcgaccat ccagagggcc
    28141 gcttgctagc gctcttaatc ctagaaatgg ggctcttgcc cagtgagatt ttagccatca
    28201 aggttgcgga catcaatctg gattttcagg tgttgcgaat cagcaaggct tcccaacaga
    28261 ggattgtcac cattcccacg gccttgcttt cagaattgga acccttgatg gggcagacct
    28321 atctttttga aagaggaggg aaaccctatt ctcgtcagtg ggcctttcgt cagttagaat
    28381 cttttgtcaa ggagaaaggt tttccatcct tatcagctca agtcttacgt gaacagttta
    28441 ttttaagaca aatagaaaac aaggtcgatt tgtacgaaat tgcaaaaaaa ttaggattaa
    28501 aaacagtcct gaccttagaa aaatatagat aatggatatt aaattaaaag attttgaagg
    28561 acccctggac ttgctcttgc atctggtttc taagtaccag atggatatct acgatgtgcc
    28621 cattacggaa gtcatcgaac agtatctagc ctatgtctca accctgcagg ccatgcgtct
    28681 ggaagtgacg ggtgagtaca tggtcatggc tagtcagctc atgctgatta agagtcgtaa
    28741 actccttccg aaggtagcag aagtgacaga cttgggggat gacctggagc aggacctcct
    28801 ctctcaaatc gaagaatatc gcaagttcaa gctcttgggt gagcacttgg aagccaagca
    28861 ccaagaacgg gcccagtatt attccaaagc gccgacagag ttgatttacg aagatgcgga
    28921 gcttgtgcat gacaagacga ccattgacct ctttttggct ttttcaaata tcctagccaa
    28981 gaaaaaagag gagtttgcac aaaatcacac gactatcttg cgggatgagt ataagattga
    29041 ggacatgatg attatcgtga aagagtcctt gattggacga gatcaattgc gcttgcagga
    29101 tttgttcaag gaagcccaga atgtccaaga ggtcatcacc ctctttttgg caaccctaga
    29161 gttaatcaaa acccaggagc tgatcctcgt gcaagaggag agtttcggag atatctatct
    29221 catggaaaag aaggaagaaa gtcaagtgcc tcaaagctag acttgataga gaggaaagat
    29281 gagtacttta gcaaaaatag aagcgctctt gtttgtagcg ggtgaagatg ggattcgggt
    29341 ccgccagtta gctgaactcc tctctctgcc accgacaggc atccagcaga gtttaggaaa
    29401 attagcccag aagtatgaaa aggacccaga ttccagtttg gctttgattg agacaagtgg
    29461 tgcttataga ttggtgacca agcctcaatt tgcagagatt ttgaaggaat actctaaggc
    29521 gcctatcaac cagagcttgt ctcgggctgc ccttgagacc ttgtccatta ttgcctacaa
    29581 acagccgatt acgcggatag aaattgatgc catccgtggg gttaactcga gtggagcctt
    29641 ggcaaagttg caagcttttg acctgataaa ggaagacggg aaaaaggaag tattggggcg
    29701 ccccaacctc tatgtgacta cggattattt cctagattac atggggataa accatttaga
    29761 agaattacca gtgattgatg agcttgagat tcaagcccaa gaaagccaat tatttggtga
    29821 aaggatagaa gaagatgaga atcaataagt atattgccca cgcaggtgtg gccagtagga
    29881 gaaaagcaga agagctgatc aagcaaggtt tggtgacggt taacggccaa gtggtgcgtg
    29941 aactagcaac cactatcaag tcaggcgaca aggtcgaagt tgaaggtcaa cctatctaca
    30001 acgaagaaaa ggtctattat ctgcttaaca aaccacgcgg tgtcatttcc agtgtaacag
    30061 atgacaaggg tcgcaagacg gttgtcgacc tcttgcccaa tgtcaaagag cgcatttacc
    30121 ctgtgggtcg tttggactgg gatacatcag gagtcttgat tttgaccaat gatggggact
    30181 ttacagacga gatgattcac cctcgtaatg agattgacaa ggtttatgtc gcgcgtgtta
    30241 aaggtgtggc caataaggac aatcttcgcc ccttgacccg tggtcttgag attgatggta
    30301 agaaaaccaa gccagctgtt tatgaaattc tcaaagtgga cccagtcaaa aatcgctctg
    30361 tggtgcagtt gaccatccat gaagggcgta accatcaggt taaaaagatg tttgaagctg
    30421 ttggtctcca agtagataag ttgtctcgga ctcgtttcgg acacctagac ttgacaggac
    30481 tccgtccagg agaatcccgt cgtcttaata aaaaagaaat cagccaacta cacaccatgg
    30541 ctgtaactaa gaaataatga aacgaatttt aatagcgcct gtgcgctttt accaacgttt
    30601 tatctcacca gtctttccac cctcttgtcg ctttgagctg acttgttcca actacatgat
    30661 tcaggctatt gaaaaacatg gttttaaggg ggtattgatg agcttggctc ggattttacg
    30721 ttgtcatccc tggtcgaaaa caggtaagga ccccgttcca gaccactttt cccttaaacg
    30781 aaatcaagaa ggggaatgag gtggggtaaa tagatttcaa aatgataaaa acgcatccta
    30841 tcaggtttga ataaacttga taggatgcgt tttagaatgt caaaatttta tactcttcga
    30901 aaatctcttc aaaccgcgtc agctttcatc tgcaacctca aaacagtgtt ttgagcaacc
    30961 tgcggctagt tttctagttt gctctttgat tttcattgag tattaaattg agtttgaagt
    31021 ggcttatttc aaagcttttt gtatgtcttc aatcatgagt tttgttgatt caagtccgcc
    31081 tccgcttaga taccagaggt ctggtgttag ttggataatc ttaccatttt tagcagcagg
    31141 tgtttcagcg ataagggcat tttctaggac accgtcgttg ctagagttgt ccccaccgat
    31201 ggcaagggta cggttgatga caaagaggat gtcagggttg atttctttga cactttcaaa
    31261 gctgacttct tgtccgtggc gtgagtcttc aaattttgta tcagttggtt tgaatttcaa
    31321 ggtttggtac aagaaagaga aacgagattt ggcaccaaag gctgccattt ttccttcatt
    31381 aaggaggatc gcaagggctt ttttgtcaga gctttcattt ttagtagcga cttcttggat
    31441 gctcttgtct agcttggcca attcttcctt ggctttttgt gtaccagttt cgccgaaggc
    31501 acttgctaag gattcgatat tagccttggt agaagtccag tagtcgtcct tgcttgcttg
    31561 gaagagaacg gttggggcga tttctttgaa tttgtctacg aatttttgtg tacgtggtga
    31621 agcgataatc aaatcaggtt caagggcggc gatagcttct aaatcaggtt ctttcataga
    31681 accaacattt ttgacagttc ccactaggtc ttttagataa gtcggaacag tttttgtagg
    31741 cattccgacg atattttttt caaatcctaa agcgcgaata gtatccgcag cgccgaggtc
    31801 aaaggtcaca atcttttcag gaactttgga aagtttgacc tcgtccagtg aacttttaat
    31861 ggttacctct gttggagcag agctactggg ctctgtctga ctagtgcttg agtttgtact
    31921 acatgcacca agtaggagca agaaactggc cactagggca atgaaataaa gtttaaggga
    31981 tgttttcata atttctcctt tttaaaatgt gataacgatt tagggagtct cttaatctta
    32041 ttgactaaga gactgaaggt tctctaactt gagcttttat gttactagct atagatacag
    32101 atctttttgt cattgatatc agctagcgtg atgggaatct cataaagttg actgagcagg
    32161 tcagcctgca tgatttgatc ggttcttccc ttgctaaaga cctggccgtc cttgaaggcg
    32221 acaatttcat ctgcatactg actggccatg ttgatatcgt ggaggacgat gataatggtc
    32281 ttgccgagtt cctccaccag tcgtcgaaga atctgcatca tgctgacgct ttgcttgata
    32341 tcgagattgt tgagtggttc gtccagcaag ataaagtccg tatcctgggc cagtaccata
    32401 gcgataaaga cgcgctggag ttgcccccct gacaggctat tgatgtagcg gtcttttaag
    32461 ttggtcagtt ccaaatagtt cagagtttct cggatttttt cccagtcttc tgatctaagt
    32521 cgacctcggc tgtagggaaa acgtccaaaa ctgaccagtt cttcaacagt caatttggct
    32581 tggtaattga ttttctgttt taggatggtt agttcttggg ccagttcttg cgaattccag
    32641 ctctcgattt cacgtccttt gatactgaga actccctgat ctttcttggt tagtctgctc
    32701 atgatggaga ggagagtcga ttttccagca ccatttggac caataaaggc tgtcagtttt
    32761 tgaggactga cttcaagcga aatgccttgc aaaatatcct gtttttgaat ggatttgtca
    32821 atgttttcca gtttcactga cgagacctcc tatatagtaa gataaagaat aagaagccac
    32881 ccacactctc aatgatcata ctgatacgaa tttccagtgc aaagactcgt tcaatcaagg
    32941 cttgccccaa ggttaagcta ataaatccaa ccagaatggc cactataaag agtaacttgt
    33001 gctgatagtc tttgacaatc aggtaggtga ggttggccag cataaagccg aagaaggcca
    33061 taggtcctac caaggcagtg gccgttgagg tcaaaagcac gattccccag aggagctctt
    33121 tctgttcttt ttcaacatcg agtcccaata tctgagccgt ttctctttgc aggtgcaaga
    33181 catctagaac gactgctttt cgaaagaaaa agattgtcaa agcgaggatg ttcagagaac
    33241 cgatggctag gatggaagtg ttgagatgtt gaaaggaggc aaaaagacta ttttgcagtt
    33301 tatcgtattc gtttggatcc attaggactt gaaggaaggt gctgatattt cgaaagagac
    33361 ttctgagcgc tagacagttc agcaggatga agaccaggtc ttgcttcatc agtgtcttca
    33421 agtaaccttg taaggcgaga aagaagaggg actggacaag aagtaagact aggaattcta
    33481 agatagggga tttgccaagt tgaagaaact tgctttcaaa aaccagtagt agggtttgta
    33541 gtaggacgta gaaggattca attcccaaaa tactaggcgt caggaagcga ttttccgtca
    33601 gggtttgaaa actaatggtc gaaatcccag tcgcgatggc taccaagaga taaacgatga
    33661 tcttttggga acgcaacttc caagcaaagg ctgacaagtg agtgatgggc caaaagtaga
    33721 gaagacaagc tccgatggca agaataatga gaatccagaa gagcttggta tgtttgcttt
    33781 tagtctgcat cttttcgtcc ccctctccag agaagtagga taaagacgag actaccgatg
    33841 attcctagca agagactgac agacaactca tagggcctaa tcagaactcg ggataggata
    33901 tcgcaagcca gaactagatt ggcaccaacc agtgcgacca tgagtttggt ttgacttaga
    33961 ttatctccat agcgcttgcg aacaagattg ggaacgataa ctccgagaaa tggtaggcca
    34021 cccacggtaa tcatggtgac gcttgtcgtt agcgccacca gaaagagggc cagtttttca
    34081 agtagggagt aggaaatccc caaactctcg ctggtttctt tccctagatt catgatggtg
    34141 aaggtttggg ataatttcca aacggttatc aggatgatga ggcctaagaa gagccactca
    34201 tactgatggg tctgaatcat ggagaaggag ccctgggtcc aggcagtcat actctgaacc
    34261 agattgaaac gataggcgat aacttctgtg actgagccga taatcccgct atagatgatc
    34321 ccaatcagag gcaacaccca cctttccttt acagtaaaaa tggtcataaa ggctaggaag
    34381 aagagggtga atacgatgga tgaaacaaaa gcgaagagca tcttttgggt cagactagcc
    34441 gatggaaaga caaaaaggct cagcaccatt cccagtttgg cggcttcagt cgttccaact
    34501 gtactcggtg cagcaaactg attttgggta atagtctgca tgagaaggcc tgccatactc
    34561 atactagagg cagtcaggag aatactgata gttcttggga gacgggactc ttgaaaaagg
    34621 agccaggtct gctggtcgaa atcaaatagc tttccccatg aaaaatcact ggtcccaatg
    34681 ctaatagaga gaaagactag gagtagaagt aagccaatta aataatgaga aagtttcata
    34741 ccccgtcctt tcatgtagat ttggtatcga aagatatctg cggatataaa tgtaacatta
    34801 tttttctaat ctgtcaataa aatttctgac aatttaataa atataacaag gagagagcaa
    34861 caagactttc tcctttgtta tcctattcta aaatgttttt accttaatct gataaaataa
    34921 tatcttcgag ggagtagcta gccgtccaat caagatattg tttagctttt gaagcatctg
    34981 ctaggacact ggctgggtca ctagcacgtc gagcaacaat ctcgtgtggg attttttaat
    35041 ttagtaattc ttcagcagtt ttaaagattt ctttgatagt atagcctttt ttagttccta
    35101 agttaaagat ttgagaagaa ctgtcttctt gaaataggta gttcattcct ttaacatgag
    35161 cctatgcaag gtccaagaca taaatgtaat ctcgaataca tgaaccgtca cgtgtatcgt
    35221 agtcatctcc aaatattttt aagctatcat tttgtcccaa tgcggtcttg ttgatatttg
    35281 gaatgatgtg agttggattt ttcacacgca gaccgtttga agcatccatt tcagccccag
    35341 aagcattaaa gtaacggaaa ataacatatt tccagtcgta gcgattggcc atccagtaaa
    35401 tcattcgttc gcccatcagt tttgtctctg cataagggtt gacagggtcg agcagggtat
    35461 cttcagtcac cggcttgtca atacagttat ttccatagag agaagcagtc gaagagaaca
    35521 tgattttttg aatgccaact tcagataaga ctttgagaac ttggttcata ccagcaacgt
    35581 tggcagtgaa gtatttactt ggattttcaa tactttcgct cacaacaatt tcacctgcac
    35641 aatggaggac agcatcaatc tgattttctt ctaagtaagc ctttaaggcg ctagcatcat
    35701 aaacatccag ttctttaaag ctagcacgac tatccacagc cgctcgattt cctgtggaga
    35761 gattatcgag gacatgcacc tgatagccag catttaaaag agctttaacg gtatgggagc
    35821 caatgtagct agtcccacct gtaacaagaa ttgttttggt catgattttt tccttttcta
    35881 gttttgtact atagtaaatt gaaataagat atgaacaact ctattaggaa agtcaaatta
    35941 atttctagaa atgttttagc agctacagcg tactattcca aactcaacca actatatatt
    36001 taaagaaaga agaaagggaa gtcaactatt ttctgtaaat ttcatgaaaa atctaaacaa
    36061 ctttgatggt gtattgtttt tttgtttgga aataaatatt cgagttaatt ttggaatgtt
    36121 tactagattt tgcactacat gcaagagaat actatccttt tctaagatag agcaggacta
    36181 agatactaac ttagaaatcc accttcccac tatccttctc ctataaaaag tggtaaaatg
    36241 gatgaaagaa agaaggaact gaaatgacaa cattattttc aaaaattaaa gaagtaacag
    36301 aacttgctgc agtctcaggt catgaagcgc ctgtccgtgc ttatcttcgt gaaaagttga
    36361 caccgcatgt ggatgaagtg gtgacagatg gcttgggtgg tatttttggt atcaaacatt
    36421 cagaagctgt ggatgcaccg cgcgtcttgg tcgcttctca tatggacgaa gttggtttta
    36481 tggtcagcga aatcaagcta gatggtacct tccgtgtcgt agaaatcggt ggctggaacc
    36541 ccatggtggt tagcagccaa cgtttcaaac tcttgactcg tgatggtcat gaaattcctg
    36601 tgatttcagg ttctgttcct ccgcatttga ctcgtggaaa ggggggacca accatgccag
    36661 ccattgccga tatcgttttt gatggtggtt ttgcggacaa ggctgaggca gaaagttttg
    36721 gcatccgtcc tggtgatacc atcgtaccag atagttctgc aattttgaca gccaatgaaa
    36781 aaaatatcat ctcaaaagct tgggataacc gctacggtgt cctcatggta agcgagctag
    36841 ctgaagcttt atcaggtcaa aaactcggca atgaactcta tctgggttct aacgtccaag
    36901 aagaagttgg tctgcgtggc gctcatacct ctacaaccaa gtttgaccca gaagtcttcc
    36961 tcgcagttga ttgctcacca gcaggtgatg tctacggtgg tcaaggcaag attggagatg
    37021 gaaccttgat tcgtttctat gatccaggtc acttgcttct cccagggatg aaggatttcc
    37081 ttttgacaac ggctgaagaa gctggtatca agtaccaata ctactgtggt aaaggcggaa
    37141 cagatgcagg tgcagctcat ctgaaaaatg gtggtgtccc atcaacaact atcggtgtct
    37201 gcgctcgtta tatccattct caccaaaccc tctatgcaat ggatgacttc ctagaagcgc
    37261 aagctttctt acaagccttg gtgaagaaat tggatcgttc aacggttgat ttgattaaac
    37321 attattaaac cataagggag gtggtaggga tggcagaacc aaacctagaa agccttataa
    37381 aagatcttta caatcatgct cgacatgatt tgagtgaaga tttagttgct gctctcctag
    37441 agactactaa aaaactgcct actacaaatg agcaattgca ggcagttcgt ctctcaggcc
    37501 tggtcaatcg tgaattgctc ctaaatccca aacatccagc acctgagttg ctcaacttgg
    37561 ctcgctttat caaaagagaa gaagccaagt acagaggaac tgcgacttct gcgcttatgt
    37621 atgaggaact ctttaaaatg ctttgattcc attgtggatc aaagcatttt ttataagacc
    37681 tatctcgtga gcgttcaaat agtagtaaca aggaatcatg agaagtcagc cgagaccata
    37741 gtagtgaaga aacttctgta atggaagtgg agtgaagtga ggaatcgtca aacggtaggg
    37801 gataggctgt ttgaagggtg ctacgaaaaa gatagggtaa ggtgaaatta tagcggaatg
    37861 aaataagata tgaacaaatt gattaggaaa atcaaatgaa tttatagaaa tcttttagca
    37921 gtcatggcgt cctattctag tttcaaaatg ctataaatac gaacaaattg attgggaaat
    37981 tcaaatcgct ttctatcaat gttttagaag atacagtgcc ctagtccaac ttcaatatac
    38041 tataaaagaa cagatggaag caattatgat ttacttctat ctttaaaata aatgatctga
    38101 taggaaaaat gtgtcccctc ataaaaaata ggatagtacg gatggaaggc ttttgtagac
    38161 tggaggacga aggaatttag aaactctcgt taaaagttag ttgagccgga gtatggtggt
    38221 gtgaataatt atcaaaaatt atttccaaat cgaaatagtt gacagttaga acgatgagtg
    38281 ttacaattat tttattcatt tcgacatcga aataaattgg aggtgttatg aaagatagtc
    38341 atttgctagc ccatcatatt cgtttgttga atgggcggat ttttcaaaag ttactgagtc
    38401 aagatcctga ggctctttat aggggtgaac agggcaagat tttagcggtt ttatggaata
    38461 gtgaaactgg ctgcgcaact gcgacagata tcgcgcttgc gactgggctt gcgaataata
    38521 cgctgacgac tatgataaaa aagctagagg aacaaaagct tgtaattgtt agtccgtgtg
    38581 gaaaagacaa gcgtaagaag tatttagttt taacggagtt aggcaagtcc cagaaagaag
    38641 tggggcatcg tgtcagtcag aaattggata ctatctttta caaaggattt tcagaggaag
    38701 aaattcacca atttgaaggt tttcaagaaa gaattttggc gaatctgaaa gagaagggaa
    38761 atgaggttta gaatatgtca caacaagtga aaaatgctca caacctatac atccatgcca
    38821 ttcaagacgg acgagttgct gaggctcaag cccagtctgt aggggatacc tatatccaac
    38881 attcgacagg tgttcctgac gggaaagaag gatttgcagc cttctttgca gatttctttg
    38941 agcgtcatcc agagcgtcag attaagattg tccgcaccat tgaggatggc aatctggtct
    39001 ttgttcatgt tcatcaatat ctgaatggtg gagaagctca atgggtgacg acggatactt
    39061 tccgtgcgga tgagaatggt tgtattgttg agcattggga tgtcattgac tactatcgaa
    39121 cacctgaaaa tgaccaacta gatcaaattt ttggagattt tgaaatcaag gatttggata
    39181 agaaagcaga aaataaaaag ctggttcgcc gtttcttgac agaaattttc caaaatgggg
    39241 agctagagca gtggagtgat tatgtggcag acgatttgat tcagcataat catgagattg
    39301 gacaaggaag tgctgcttat aaaaactatg tggctgaata tagtgtcact tttgactttg
    39361 ttttccaact cttaggacaa ggaaactatg tggttagcta tggtcagact cagattgatg
    39421 gcgttgctta tgcccagtac gatatcttcc gtttagagaa cgggaaaatt gtggagcatt
    39481 gggataataa ggaagtcatg cctaaggtag aagacttgac taatcgaggg aagttttaaa
    39541 ttgaggacaa agaatgattg aatacaaaaa tgtagcactg cgctacacag aaaaggatgt
    39601 cttgagagat gtcaacttac agattgagga tggggaattt atggttttag tagggccttc
    39661 tgggtcaggt aagacgacca tgctcaagat gattaaccgt cttttggaac caactgatgg
    39721 aaatatttat atggatggga agcgcatcaa agactatgat gagcgtgaac ttcgtctttc
    39781 tactggttat gttttacagg ctattgctct ttttccaaat ctaacagttg cggaaaatat
    39841 tgctctcatt cctgaaatga aggggtggag caaggaagaa attacgaaga aaacagaaga
    39901 gcttttggct aaggttggtt taccagtagc cgagtatggg catcgcttac ctagtgaatt
    39961 atctggtgga gaacagcaac gggtcggtat tgtccgagct atgattggtc agcccaagat
    40021 tttcctcatg gatgaaccct tttcggcctt ggatgctatt tcgagaaaac agttgcaggt
    40081 tctgacaaaa gaattgcata aagagtttgg gatgacaacg atttttgtaa cccatgatac
    40141 ggatgaagcc ttgaagttgg cggaccgtat tgctgtcttg caggatggag aaattcgcca
    40201 ggtagcgaat cccgagacaa ttttaaaagt gcctgcaaca gactttgtag cagacttgtt
    40261 tggaggtagt gttcatgact aatttaattg caacttttca ggatcgtttt agtgattggt
    40321 tgacagctct atctcaacat ttgcagttgt cacttttgac cttgttacta gctattttgc
    40381 ttgcgattcc cttggctgtt tttcttcgct atcatgagaa gctggccgac tgggtcttgc
    40441 agattgcagg tattttccag accatcccgt ctctggcctt gttggggctc tttatccctt
    40501 tgatgggaat tgggaccttg ccggctttga cagctctagt gatttatgcg attttcccta
    40561 ttttgcaaaa tactatcact gggctgaagg gaattgatcc gaacctgcaa gaggctggga
    40621 ttgcctttgg gatgaccaga tgggaacgtc tcaagaaatt tgaaattcca ctcgccatgc
    40681 ctgttatcat gtctgggatt cggacggcag ctgttttgat tatcggtacg gcaaccttgg
    40741 cggccttgat tggagcaggg ggactgggtt cctttatcct gttgggaatt gaccgtaata
    40801 atgccagttt gattttgatt ggggcacttt cttctgcagt gcttgctatt gcctttaact
    40861 tcctactaaa agtaatggaa aaagcaaaat tacggacgat tttctcaggt tttgccttgg
    40921 tggctttatt actgggtctg tcttatagtc cagctctttt ggttcaaaaa gagaaggaaa
    40981 acttggttat tgctgggaaa ataggtccag aaccagaaat tttggccaat atgtataagt
    41041 tgctgattga agaaaatacc agcatgactg cgactgttaa accgaatttt gggaagacaa
    41101 gcttccttta tgaagctctg aaaaaaggcg atattgacat ctatcctgaa tttactggta
    41161 cggtgactga aagtttgctt caaccatcac ccaaggtgag tcatgaacca gaacaggttt
    41221 atcaggtggc gcgtgatggc attgctaagc aggatcatct agcctatctc aaacccatgt
    41281 cttatcaaaa cacctatgct gtagctgttc cgaaaaagat tgctcaagaa tatggcttga
    41341 agaccatttc agacttgaaa aaagtggaag ggcagttgaa ggcaggtttt acactcgagt
    41401 ttaacgaccg tgaagatgga aataagggct tgcaatcaat gtatggtctc aatctcaatg
    41461 tagcgaccat ggagccagcc cttcgctatc aggctattca gtcaggtgat attcaaatta
    41521 cggacgccta ttcgactgat gcggaattgg agcgttatga tttacaggtc ttggaagatg
    41581 acaagcaact cttcccacct tatcaagggg ctccactcat gaaagaagct cttctcaaga
    41641 aacacccaga gttggaaaga gttcttaata cattggctgg taagattaca gaaagccaga
    41701 tgagccagct caactaccaa gtcggtgttg aaggcaagtc agcagagcaa gtagccaagg
    41761 agtttctcca agaacaaggt ttgttgaaga aatgatggga cagagacttt aaacatactg
    41821 aactcaactt ccttaaacga ctagataaaa gaatgctcag acaatttcgt ctgggctttt
    41881 ttgatgtgag aatgactgaa tgtcacttaa aatggaaaga aagagaaaat tttcatgatt
    41941 ttctaaaatt ttactgtaaa gacacttgac tattcataaa atagatgtat aatattttgt
    42001 gaactactta acaaataagg ggtttcagct catgtcgact aaggttagaa atcttgtgta
    42061 taggcagttc attatctaat agagcgttgc gtccgaaagt ctatccagac acggctcttt
    42121 aaaaacaaaa ggagaaatga tgcatactta tttgcaaaag aaaattgaaa atatcaaaac
    42181 aaccctaggt gaaatgtcag gtggttaccg tcgtatggtt gcggctatgg ctgatttagg
    42241 attttcagga actatgaaga ctatctgaga tgacctcttt gcccatcgta gttttgccca
    42301 gtggatttat ttgctggttt taggaagttt tcctctctgg ctggagttgg tttacgaaca
    42361 tcgtattgtt gactggattg ggatgatttg tagcttgaca gggattatct gtgtaatctt
    42421 tgtatcggaa ggtcgagcaa gtaattatct ttttggcttg attaactctg ttatttacct
    42481 tattttggcc ctacagaaag gcttttatgg tgaggtgctg acgacacttt acttcacagt
    42541 catgcagcca attggacttc tagtttggat ttatcaggca cagtttaaga aggaaaagca
    42601 ggagtttgtc gcgcgtaaac tggacggcaa gggctggaca aagtatcttt ccattagtgt
    42661 gctttggtgg ttggcctttg gcttcattta tcagtctatt ggtgccaatc gtccctatcg
    42721 tgattcaatc acagatgcaa ccaatggggt agggcaaatc ctcatgacag ctgtttaccg
    42781 tgaacagtgg atattctggg cggctaccaa tgtcttttca atctatctct ggtggggaga
    42841 aagcctgcaa attcaaggga aatatctaat ttatctcatt aacagtctag ttggttggta
    42901 tcaatggagc aaggcagcta agcagaatac tgatttactt aactaggaaa agatgtttga
    42961 aagtgctgtt ttgagatttc gattaaaaca gatatagttg ataatcaagg atttatagta
    43021 tgaaaaagag gatcggcggg tcctcttttg ttgttgaaaa gataaaaaac tcagtaacct
    43081 agaaataaga caactgaagc tttactctat attcaatttt taggaatgag aaggtctaga
    43141 taaaattgga caacttcctg atctgtgaaa tcttgacctt ttttgagcca ccaggtcaat
    43201 gtctcgataa agttggacat gaccaagtgt tggaggtaag aagtaggcag attagggtgg
    43261 gcttctttta aattatcagc tagcacggaa tagacgtggt gctcaagctc tctctagagt
    43321 tgacggagga agtagtcatt tttggaaaat agcagactgg tgatatggtc ttggttttta
    43381 tgaaaatgga gaaagaggtg ggcgaggtag tcctcggttg aaatggcttg ctctctttca
    43441 aaaagatgat ggaagaggta gcggcagagc tggtccagaa gaagctcctt actctcatag
    43501 tgacagtaaa aggtggatcg tcccacatct gcgagatcaa tgatatcctg aacagtagtg
    43561 gcctcgtagc ccttagcatt caaaagttgt ataaaagctt gatagatggc ttttttggtt
    43621 ttgctgatac ggcggtcaat gttagtcata tggacactta aggcaaattg ttcagaactg
    43681 aataaagctg acgttttgct tctatccttt ctttgagttt tagtggataa tgataatgaa
    43741 caaggtgttc ataaatctat tataacaaag gaatgagaaa tatgaaggca aaatatgctg
    43801 tttgggtggc ttttttctta aatttgactt atgccattgt tgagtttatt gcaggtggaa
    43861 tatttggttc tagcgctgtt cttgctgact ctgtgcatga cttggtagat gcgattgcaa
    43921 ttggaatatc agctttttta gaaacaatct ccaatcgtga agaagacaat cagtacacct
    43981 tgggctataa gcggtttagc ctgctaggag ccttggtaac agctgtgatt ctcgtaacgg
    44041 gctctgttct agtcattttg gaaaatgtca cgaagatttt gcatccgcaa ccagtcaatg
    44101 atgaggggat tctctggtta ggaattattg cgattactat caatatgtta gcgagtctgg
    44161 tggttggtaa gggaaagaca aagaatgagt ctattctgag tctgcatttt ctggaagata
    44221 cgctagggtg ggtagctgtt atcctgatgg cgattgttct tcgatttacg gactggtata
    44281 tcctagatcc tcttttgtcc cttgtcattt ctttctttat tctttcaaaa gcccttccac
    44341 gtttttggtc tacactcaag attttcttgg atgctgtgcc agaaggtctt gatatcaagc
    44401 aagtaaagag tggcctggag cgattggaca atgtggccag ccttaatcag cttaatctct
    44461 ggactatgga tgctttggaa aaaaatgcca ttgtccatgt ttgtctaaaa gaaatggaac
    44521 atatggaaac ttgtaaagag tctattcgaa ttttcctaaa agattgtggt tttcaaaata
    44581 ttaccattga aattgatgct gacctagaaa ctcaccaaac ccataagcga aaggtgtgtg
    44641 acttggaacg gagttatgag catcaacatt agaaaaaagt gaaaaatact tgggtactat
    44701 cttatttgga atagagtaat ttctttatta tttaaatatt tcaaaaattg gtaagagaag
    44761 agcattgtat aaactccaga tatatgattg ttaatgataa aaatttttcg attagataca
    44821 aaatgcttga cttggagtca actcaaagtt atataataag ataagtgagt tagaatagcg
    44881 tgaattcagt gaatgaaatg agaggaggtt agcgtgtgaa tattaaatct gccagtgatt
    44941 tgttgggaat ttcagcggat acgattcggt attatgaacg ggttggtctt gtgccaccga
    45001 ttactcgtac tgctactggg attcgtgatt ttcaagatca ggatatcgaa gcgctggaat
    45061 ttattaagtg ttttcgttcg gcgggtgtct ctgtagatag tttagttgac tatatgtcgc
    45121 tctaccaaaa gggagatgaa acgagagagg agaggcttgg tattttagaa gaggaaaagc
    45181 aaaaattaga ggagcgcttg tctcagctac agacagcttt aaatcgttta aatctcaaaa
    45241 ttaaacttta taaggaagga aaattttaaa tgaaatcagc agtatataca aaggcaggtc
    45301 aggttggact tgcgtccgca aataatagaa gcggatgatg tgattattcg tgtggttcgt
    45361 gcgtgcgttt gtggttcaga tttatggagg taccgtaatc cagaaacgaa agctggacac
    45421 aaaaatagtg gacacgaagc gattgggatt gttgaagaag ctggggaagc cattacgacg
    45481 gtgaaaccag gtgattttgt gattgtccct tttacacatg gatgtggtga gtgtgatgcc
    45541 tgtcttgctg gatttgacgg ttcttgcgac aatcatattg gcaataattt ggggggtgat
    45601 tttcaggcag aatatattcg cttccactat gcaaactggg cgctggttaa aatccctggt
    45661 caaccttctg actatacaga agggatgctc aagtcccttt tgactcttgc agatgtcatg
    45721 ccgacaggct atcatgcggc gcgtgttgca aatgttcaaa aaggggacaa ggttgttgtt
    45781 atcggtgatg gggctgttgg tcaatgtgct gtcatcgcgg ctaagatgcg tggagcatca
    45841 caaattatcc ttatgagccg tcatgaagac cgtcaaaaga tggctatgga gtcaggtgcg
    45901 acagctgttg ttgcagaacg tggtcaagaa ggaattacca aggtgcgtga aatcctcggt
    45961 ggaggagcag atgcagcact tgaatgtgtt ggtacggagg ctgctataga acaggcgcta
    46021 ggtgttcttc ataatggagg gcgtatgggc tttgtaggag tcccacacta taataatcgt
    46081 gctcttggtt cgacatttat gcaaaatatc tctgtagcag gtggggcagc ttctgctaca
    46141 acatacgata agcaattttt actaaaagcc gtccttgatg gtgatatcaa tccaggtcgc
    46201 gtctttactt caagttataa actggaagat atcgaccaag cctataaaga tatggatgaa
    46261 cgtaagacaa ttaagtctat gattgtaatc gaataaaaaa cgaataggag ttttagaact
    46321 ctattcgttt tttatgttat cctattcttg atttagggta ctttctctta atgtcagtct
    46381 ggttcccagc atggtcaggc tagggatttt ccgaccgtgg aggacttcct tgttaagaat
    46441 atccatacct gctcgcccca tttcttcagt ataaactgtg atgctggaga ggggaggata
    46501 aacctgcttg gtcaggctgg tgtcgttaaa ggaaatgagg ctgacacggt ctggtaggct
    46561 gattccagct tcttggagcg cacgaagggc accgatggct aaactatcgc tggctgcgaa
    46621 aaatgctggt gggagttggt ctcccaagtt ctgaatggct tccttcatca agtcatagcc
    46681 agactgggca gtaaagtttc cttgaaagat cagttcatca tgatagattc cttttgcttg
    46741 actgtagttt ctgaaatttt ccagccgctt atcctcaatg atttcttctt ggtcagttgt
    46801 ttcttcaagg cctgttagaa tcccgatacg gtccattcct tggctgagga aataatcgac
    46861 aacctgtttc atagcagtgt aaaaatccgt gataatacag gtatgtccca gggaaagtgt
    46921 atcgctgtct agaaatacaa gaggcttttg gtattcttca aaggcagaaa tctgagctcg
    46981 actaaacttt ccgatgcaga gaatcccaat cacttcctcg cttagggtaa aagggtggtc
    47041 attaaagtag cgcaagatat cgtagtccaa ctcttgggct cttttttcta ttcctaggcg
    47101 aatctggtag tagtagaggt cgtctagctc cccttgttcg ctgacccatt gaataatggc
    47161 aatcttttgc ttgggtttat gggactcgcc tgtcttgagg tgcttggtgt agcccagctc
    47221 ttcagcaacg gttaaaatac ggtgtctggt ttcttctgta acagataggc tctggtcgcg
    47281 gttgaggaca cgggatacgg tcgcgataga gacagaggct agctgtgcaa tgtcttttaa
    47341 ggtagccata aatcctcctt gattaggtta gtatatcata tttttcttct ttttactgat
    47401 attttactaa aattttagta aaaaggattg accttgggaa attccttgga tacaatagaa
    47461 gaaaacgatt acacgttaag gtggcttaac ggacagtcaa aggagaaatc atatgacaca
    47521 acatcttact gctgaaactc ttcgcaaaga ctttcttgct gtttttggtc aagaagcaga
    47581 ccaaactttc ttttcaccag gtcgtatcaa tttgattggt gaacacacag actacaacgg
    47641 tgggcacgtt tttcctgcta ctatttcctt gggaacttac ggtgcagctc gtaagcgtga
    47701 cgaccaagtt ttgcgtttct actcagctaa ctttgaggac aagggcatta tcgaagtgcc
    47761 tctcgctgac ctcaagtttg aaaaagagca caactggacc aattatccaa aaggtgtcct
    47821 tcatttcttg caagaagctg ggcacgtgat tgacaaaggt tttgattttt atgtttatgg
    47881 gaatatccca aatggtgctg gtttgtcttc ttcagcatcc ttggagctct tgacaggggt
    47941 agtggcagag catctctttg atttaaaatt agagcgtttg gatttggtta aaatcggaaa
    48001 acaaacagaa aataacttta tcggagtcaa ctctggtatc atggaccagt ttgctattgg
    48061 tatgggggct gatcaacgtg ctatttacct tgataccaac accttagagt atgatttggt
    48121 gccacttgat ttgaaggaca atgtcgttgt tatcatgaac accaacaaac gccgtgaatt
    48181 ggcggattct aaatacaatg aacgtcgtgc tgagtgtgaa aaagcagtgg aagaattgca
    48241 agttgccttg gatattcaga ccctgggtga attggacgag tgggccgttg accaatatag
    48301 ctatttgatt aaagatgaaa atcgtttgaa acgtgctcgc catgctgtgc ttgaaaacca
    48361 acgtaccctt aaagctcaag cagcccttca agcaggtgat ttggaaacat ttggtcgttt
    48421 gatgaatgcg tcacacgttt ctctggagcg tgattatgaa gtaactggtt tggaattgga
    48481 tgctcttgtt cacacagctt gggcacaaga aggagttctc ggtgctcgta tgacaggggc
    48541 tggttttggt ggctgtgcca ttgccttggt tcaaaaagat actgttgagg cctttaagga
    48601 agctgtaggc aaacactacg aggaagtagt tggatacgct ccaagcttct atatcgctga
    48661 agttgcaggt ggcactcgcg tccttgacta gtcaaaagga ggctctatag tgaccttagt
    48721 agataaattt gtaacacatg tcatttctga aagttcattt gaggaaatgg atcgaatcta
    48781 cctgacaaac cgtgttttgg cacgagtggg agaaggtgtt ttggaagttg agaccaatct
    48841 ggataaattg attgacctca aggaccagct agttgaggaa gccgttcgat tagagacgat
    48901 tgaggatagt cagactgcgc gtgaaatcct tggtactgaa ctgatggact tggtgactcc
    48961 ttgtccgagt caggtcaatc gtgacttctg ggaagcctat gcctactctc ctgagcaagc
    49021 gatagaggat ttttatcaac tcagtcggaa aaatgactac atcaaactca aggccattgc
    49081 taaaaatatc gcttatcgtg ttccatctga ttatggagaa cttgaaatta ccatcaatct
    49141 ctctaagcct gaaaaggatc cgaaagagat tgcggtagcc aagttggtgc aagctagtaa
    49201 ttatcctcag tgtcaacttt gtttagagaa tgagggttac catggtcggg tcaaccaccc
    49261 agctcgcagc aaccaccgga ttatccgttt tgaaatggtt ggtcaggaat gggggttcca
    49321 gtattcgccc tatgcttact ttaatgagca ttgtatcttt ttagatggcc agcatcgtcc
    49381 catggccatt agtcgtcaga gttttgaacg tctgttggct atcgtagagc agtttccagg
    49441 atattttgct ggatctaatg ccgacctgcc gattgtgggg ggctctattc taactcatga
    49501 tcattatcag ggaggccgtc acgtatttcc tatggaattg gctcccttgc aaaagacctt
    49561 ccgatttgct ggttttgagc aggtcaaggc tggaattatc aagtggccaa tgtctgtcct
    49621 acgcttgact tcggattcca aagaggattt gattaactta gctgataaga ttttccagga
    49681 atggcgtcag tattcagatt ctagtgtgca gattttagca gagacagacg ggacaccgca
    49741 tcacaccatc acaccaatag cgcgtaagcg tgatggacag tttgagttgg acttggtctt
    49801 gcgagacaat cagacttcag cagagcatcc tgatggcatc tatcatcccc acaaggatgt
    49861 ccaacatatc aagaaggaaa atatcggctt gattgaggtc atgggcttgg caatcttgcc
    49921 accacgtctg aaagaagaag tggagcaagt cgctagctat cttgtaggag aagctgttac
    49981 agttgccgat tatcatcagg agtgggcaga ccaactcaaa tcccaacatc cagacctaac
    50041 ggataaagaa aaagcccttg caatcgtcaa ggactctgtg ggtgctatct ttgtgcgtgt
    50101 acttgaggat gcaggagtct acaagcagac agaacaaggg cagacagcct ttatgcgctt
    50161 tgtggaacat gtcggaattt cactagacta ggagctttct ccttgcacag tcctataaaa
    50221 agtagtatca tagtgtcgtt tgaaatatca ggaggaaacg atgaaagact ttcattttga
    50281 cgctatatct gcctttgaaa attacgaaat tgaaaaaatg agagatggtc acgttgtggt
    50341 gacgaccaaa gtagtgaact cgtcgctcaa ctactatggc aatgcccatg gtggctatct
    50401 attcacgcta tgtgaccaaa tcagtggttt ggtggttatc tcgctgggac ttgatggggt
    50461 gacactccaa tcctctatca actaccttaa ggcaggaaaa ctcgacgatg tattgaccat
    50521 taaaggagaa tgtgtccatc aaggccgtac aacctgtgtg atggatgtgg atatcaccaa
    50581 tcaagagggc agaaatgtct gtaaagcaac ctttaccatg tttgtcacag gccagcggtc
    50641 agaagaaaga caggtaagga tataaagagt aatttaatag agtgaggtga attttggaat
    50701 ttataagatt tgccttactc attttttgat attgatatga tttaattcta aaatagaaaa
    50761 tttagtaatg tggtagaaaa tacaagagtt gtgttttaat ttctatggta taattaaaag
    50821 catgaagata aaagaaataa agaaagttac tttacaaccg ttcacgaaat ggacaggtgg
    50881 taaaagacaa ttattgcctg ttattagaga attaatgcct aaaacctata acaggtattt
    50941 cgaacctttt gttggaggtg gagctttatt ttttgatttg gctcctaaag atgcagttat
    51001 taatgatttt aacgctgaac taataaattg ctatcaacaa attaaggaca atcctcaaga
    51061 attgattgaa attttgaaag ttcatcagga atataattca aaagaatatt atttagattt
    51121 acgttctgca gatcgtgatg aaagaataga tatgatgtcc gaagtacaaa gagctgcacg
    51181 tattctatat atgttgagag tgaactttaa tggtctatat cgtgtgaatt ctaagaacca
    51241 atttaatgtt ccatatggac gttataagaa tcctaaaatt gttgatgagg aattgatatc
    51301 tgctatttca gtttatctaa ataacaatca actagaaatt aaagtgggag attttgaaaa
    51361 ggcaattgta gatgttcgaa caggagattt tgtgtatttt gaccctccat atattccatt
    51421 gtctgagacg agtgcattta cgtcttatac tcatgaggga ttctcttttg cagatcaagt
    51481 aagattaaga gatgtcttta agagattaag tgatacagga gcttatgtta tgttatcaaa
    51541 ttcttctagt gctttagtag aggagttgta taaggatttt aatatacatt atgttgaagc
    51601 tacccgaact aatggagcaa aatcttcaag tcgaggaaaa atttctgaaa ttatagtcac
    51661 aaattatgaa aaataacgaa tataagtatg gaggtgttct tatgacaaaa ccatactaca
    51721 ataaaaataa gatgattctt gttcattcag atacgttcaa gttcttatca aaaatgaaac
    51781 cagaaagtat ggatatgatt tttgctgatc caccttattt tttaagtaat ggtggaatat
    51841 ctaattctgg gggacaagta gtttctgttg ataaaggaga ttgggataaa atttcttcat
    51901 tcgaagaaaa acatgagttt aatcgtaaat ggattcgcct agcaaaagaa gttctgaagc
    51961 ctaatgggac ggtatggatt tcaggtagtt tgcacaacat atactcagtt ggaatggcat
    52021 tagaacaaga aggttttaaa attctgaata atattacttg gcagaaaaca aaccctgccc
    52081 ccaatttatc ttgtcgttat tttacccatt ctactgaaac cattttatgg gccagaaaaa
    52141 atgataaaaa agctcgtcat tactacaatt atgatttaat gaaagaattg aatgatggaa
    52201 aacaaatgaa agatgtctgg accggttctt taacaaagaa agttgaaaaa tgggctggga
    52261 aacatccaac tcaaaaacca gagtatttgt tagaacgtat tattttagcc tctactaaag
    52321 agggtgacta tattctagac ccatttgttg gtagtggcac tacgggtgtt gttgcgaagc
    52381 ggttaggtag aagatttata ggtatcgatg ctgaaaaaga atatttaaaa attgcaagga
    52441 agaggttgga ggcagaaaat gaaacaaact agaaattttg atgagtggtt gtcaacgatg
    52501 accgacacag tagctgactg gacttattat acagattttc ctaaggttta taaaaatgta
    52561 tctagtataa aagttgctct aaatattatg aatagtctta ttggtagtaa aaatatacaa
    52621 gaggattttt tagacttata tcaaaattat ccagaaattt tgaaagttgt gcctctactt
    52681 attgctaaac gtttgagaga tacgattatt gttaaggatc cgataaaaga tttctatttt
    52741 gattttagta aacgaaacta tagtattgaa gaatatacta tgtttttgga aaaatcaggt
    52801 atatttgatt tattgcaaaa tcatttagta tcaaatttag ttgactacgt tacaggtgtt
    52861 gaggttggta tggatactaa tgggcgcaaa aatcggactg gagatgcgat ggaaaatatt
    52921 gttcaaagct atcttgaagc tgaagggtat attttaggag agaatttatt taaagagatt
    52981 gaacaaaatg aaatagagga aattttttct gtcgatttat ctgctattac gaatgatggg
    53041 aatactgtga aacgttttga ttttgtcata aaaaatgaac aagtgcttta tctgattgag
    53101 gttaattttt attcaggaag tggttcaaaa ttaaatgaga cggctagatc ttacaaaatg
    53161 attgctgaag aaactaaagc tattcctaat gttgagttta tgtggattac tgatggacaa
    53221 ggttggtata aggctaagaa taatttacga gaaacatttg atattttacc attcttatat
    53281 aatattaacg atttggaaca taatatttta aagaatttga aataggtcca attcaattag
    53341 atgggaattg ggattgattg tatttataat caatttgtga taaacaaaaa agaggctcgc
    53401 acctcttttt cttatttctt tttatgattt aatacggcat tgaggacaat ggcgagtagg
    53461 ctggctacga cgattccgtt tgagaagaac atttggaagg ctgtcggcat gctgacaaag
    53521 agattactgt tgttgagacc gacacctgca gcgattgaaa cagctgcgat aaggaagttg
    53581 tgttcattgt tagcaaagtc aactcgggcg aggatttgca tcccttgaat agatacaaaa
    53641 ccaaacatca ccagcatggc accgccgagg acggagcttg gaatgatttg ggcaagggca
    53701 ccaaacttag gaagcagtcc aaggagaacc aggaaaccag ctgcgtagta gattggcagg
    53761 cgttttttga tgcctgacaa tttaaccaaa ccaacgtttt gtgaaaatcc ggtgtaaggg
    53821 aaggtgttaa agattcctcc gagaagtacg gccaaacctt ctgcgcggta accgttgcga
    53881 aggcgcgtgc tgtcgattgg atcctttgtg atatcagaca aggccagata aacaccagtt
    53941 gactcaacca tagacaccgt tgcgatgata cacatcatga caatagatga gatttcaaag
    54001 gttggcatcc caaagtagag tggagttggg acatggacaa gtggagctac cgcaacagga
    54061 gagaagtcca ccaagcccat agtagcagca atggcagttc caacaaccag accaatcaaa
    54121 atagagatag acttgataaa tcctttggta aagatgttga tcaagaggat aatcagaaca
    54181 gtaatagctg caagcaagag actttgacca gttggctctg gaacgttatt tcccatattt
    54241 ccaatagcga cagggatcaa ggttaaacca atcgtggtaa taacagatcc tgttacgata
    54301 gatgggaaga gattggctac ttttgagaag atgcctgaaa caagaaccac gtaaatccca
    54361 gatgcgataa gggcaccaaa catagcgcca ctaccatggc tttgcccaat cataatcaag
    54421 ggagcgaccg actggaatgc aactccaaga acgactggga gtccaatccc aaagtatttg
    54481 ttgagttgga gttggaggaa ggttgccacc ccacacatga agatatctgt agaaatcagg
    54541 taggtcaact gctcagctga atagccaagg gctgtcgcaa tcatgatggg aaccaggata
    54601 gatcctgagt acatggctag taagtgctgc aagccaagaa cggctgcttg cgagtgtttt
    54661 tcttgagttt gcattagaga tctgcctcct taaatacgac ctgaccattt tcaaaacgat
    54721 ccaaacgagc aagtgatagg acagggtagc ctgctttttc aagcaaatca cgaccatctt
    54781 ggaaggattt ctcaatcacg ataccgatag cttggactgt ggcaccggcc tgttcgatga
    54841 tttgaatcaa gcctttagca gcttggccat tagcaaggaa atcgtcgata atcaaaacct
    54901 tgtcctctgg tgagaggaat ttttcagcga tagaaacggt gctggtcacc tgtttggtaa
    54961 aggagtagac ttgagcagtt aagatgcctt cgttcatggt gatgttctta gcttttttgg
    55021 cgaaaatcat gggaacgttt aaggcttcag ctgtaaaaac ggctggggca atacccgacg
    55081 cttcaatggt tacgaccttg gtaatgccag tagcagcaaa tttttccgca aaaaccttac
    55141 caatctctcg catcaagcta aagtcaactt ggtgggttaa aaaggaatct accttgagga
    55201 tgttatcacc caagatatgc ccatccttga ggatgcgctc ttctaataat ttcataagac
    55261 ctcctaaagt ctaaaagtta atttacttgt tgtttaaata tttctatagt gatccctttt
    55321 gctaatacta tatatttgat aaaactatta cgagcgaagc gagtcttatc aaatatttcc
    55381 tgatgtagtg gtatcataga caataatctt gttattgtct atgacgggat ttttgagagt
    55441 aaaatagttc ggggaactat tttagcctaa gcctagaaat gaaagagcta ggggctcaaa
    55501 aattagggat gaaattccct ggattcctga aattattcac aggataattt cacctcccgt
    55561 ccgcactaat taagggaaat attaaaaata ttcaaaaaag acctacttaa tctctaagta
    55621 agtcccccaa ataggcatgg caaaaacggc catatctcac tgctgactta cttattgtta
    55681 ggtgttccgg caccttgtag aaacgtcgtg ccaattcacg acataaacaa gtaaaacgat
    55741 attcaatttt aaataggctt gagccaatgt ttttatttta cactaaataa ctttagaaat
    55801 caactatttt gttagtgttt tggtttaaaa aacgaacaaa cagaagagag ggcgaacaaa
    55861 aaactccgtt gtaagctaac atttatacta aatgaaaatc aaagagcaaa ctaggaagct
    55921 atccacaacc tcaaatcact gttttgaggt tgtggataga attgacagag tcagtatcat
    55981 atacctacgg taaggcaacg ttgatgtggc ttgaagagat tttcgaagag tattagaaga
    56041 tttttccatc ataaaaggca tactatcaag tttttaaaca cctgacaata tgcctttttc
    56101 taactttaaa gacttttccc aatttttatt attctactcg ctaaatctta aaaaatagcc
    56161 atttggatcc aaaactgcaa attcatgagg atagatatag tgatcactga cacgaaactt
    56221 tctcttggtc aagggacgat aaataggata gtttgccttc atcactcttt aatagagttt
    56281 tgaaacatcc tttatgccaa aggagagatt gactccacga ccaaatggat aggtcagttc
    56341 agctagttga tcctttgttc cctcctctaa cattagttga cactcttcaa gagaaagaga
    56401 aagttttctt ctggacgttg gtattcaatc ctaaaaccca gtaaaccaca gtagaaggac
    56461 cgggactgtt cgatattcga tacaagcaac tcgggaatga ccgcattgta gtccatatag
    56521 aaaatcctta caagtcaatt tccaagacaa tcggtgtatg gtcttggcga gcacctgagt
    56581 caatcatatc agatttagtg accttgtcag cgatacggtt acttgtgagc cagtagtcga
    56641 ttctccagcc tgtattgttg attttagaag ttttgctgcg ttgtgcccac caagtgtagc
    56701 gttcaggaac atcgccatga acatggcgga aggtgtctgt aaatccagtt gccaaaaggt
    56761 tggtaaatcc agcacgttcc tcgtcagtaa atccaggtga acggcggttg ctagcaggat
    56821 ttgcaaggtc gatttcattg tgggctacgt tgtagtcacc ggtcgcaagg actggttttt
    56881 ctttgtctag ttcagccaaa tactcagcat atttggcatc ccagacttgg cgttcttcca
    56941 agcgtttgag accgtcacca gcgtttggag tgtaaacttg ggttacgaaa aatgcatcaa
    57001 attctagagt gatgatacga ccttccaagt ccatggtaga aggggcaccg atttctggga
    57061 agctgatagt aggtgtaagt tctttcttat aaaggaacat ggttccagca tagcctttac
    57121 gggcaggctc ttgggaagaa cgccacgtgt tttcgtagcc tgggaagagt tcttctaaaa
    57181 tttccacgtg tttctttgta ggtcctttgg cagaaagctt ggtttcttgg atagcaatga
    57241 tatcagcatt ttcagcgacc aaggtttgta ggacttcttg ggacaatttg gcacgagctg
    57301 agtcactagt tagggcagcg tttagggaat caatattcca tgagataagt ttcataaagt
    57361 tacctttttc attcagatta tagattttat tataccaaaa aaagatctat ttccccaacg
    57421 tatagtttga aaaattactc tctttcgt
//
LOCUS       DAVDZK010000009        56221 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVDZK010000009 DAVDZK010000000
VERSION     DAVDZK010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56221
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.009"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(128..1000)
                     /locus_tag="VUX16_000630"
     CDS             complement(128..1000)
                     /locus_tag="VUX16_000630"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET8123641.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            1236..2546
                     /locus_tag="VUX16_000631"
     CDS             1236..2546
                     /locus_tag="VUX16_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET8123642.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            complement(2912..3106)
                     /locus_tag="VUX16_000632"
     CDS             complement(2912..3106)
                     /locus_tag="VUX16_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET8123643.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(3566..4294)
                     /locus_tag="VUX16_000633"
     CDS             complement(3566..4294)
                     /locus_tag="VUX16_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET8123644.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQYYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            4452..5862
                     /locus_tag="VUX16_000634"
                     /pseudo
     CDS             4452..5862
                     /locus_tag="VUX16_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            5880..7175
                     /locus_tag="VUX16_000635"
     CDS             5880..7175
                     /locus_tag="VUX16_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET8123645.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYIFAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFTLMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            7180..7488
                     /locus_tag="VUX16_000636"
     CDS             7180..7488
                     /locus_tag="VUX16_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET8123646.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTINMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            7485..7793
                     /locus_tag="VUX16_000637"
     CDS             7485..7793
                     /locus_tag="VUX16_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET8123647.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(8714..11365)
                     /gene="adhE"
                     /locus_tag="VUX16_000638"
                     /gene_synonym="adhC"
     CDS             complement(8714..11365)
                     /gene="adhE"
                     /locus_tag="VUX16_000638"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET8123648.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWISQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGHNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVKKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTSFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(11665..12075)
                     /locus_tag="VUX16_000639"
     CDS             complement(11665..12075)
                     /locus_tag="VUX16_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123649.1"
                     /translation="MENLKSFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     ILKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            complement(12062..12505)
                     /locus_tag="VUX16_000640"
     CDS             complement(12062..12505)
                     /locus_tag="VUX16_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET8123650.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNVSDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYQRVQEGCKVWLERLEKESEDGKS"
     gene            complement(12552..12851)
                     /gene="yajC"
                     /locus_tag="VUX16_000641"
     CDS             complement(12552..12851)
                     /gene="yajC"
                     /locus_tag="VUX16_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET8123651.1"
                     /translation="MNPNYTFLIMLALMVGLIFFTQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            complement(12968..14944)
                     /gene="tkt"
                     /locus_tag="VUX16_000642"
     CDS             complement(12968..14944)
                     /gene="tkt"
                     /locus_tag="VUX16_000642"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET8123652.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLR
                     INPAQPNWINRDRFILSAGHGSMFLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFVQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSIPSTDVFDKQDAAYKEEILPNAVRRRVAIEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            complement(15058..16149)
                     /gene="ulaG"
                     /locus_tag="VUX16_000643"
     CDS             complement(15058..16149)
                     /gene="ulaG"
                     /locus_tag="VUX16_000643"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET8123653.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKVTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            complement(16282..17934)
                     /locus_tag="VUX16_000644"
     CDS             complement(16282..17934)
                     /locus_tag="VUX16_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET8123654.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVV"
     gene            complement(18113..18817)
                     /locus_tag="VUX16_000645"
     CDS             complement(18113..18817)
                     /locus_tag="VUX16_000645"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET8123655.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            complement(18819..19682)
                     /locus_tag="VUX16_000646"
     CDS             complement(18819..19682)
                     /locus_tag="VUX16_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET8123656.1"
                     /translation="MVRPIGIYEKAIPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKAPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            complement(19686..20351)
                     /locus_tag="VUX16_000647"
     CDS             complement(19686..20351)
                     /locus_tag="VUX16_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET8123657.1"
                     /translation="MTKRIPNLQVALDYSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     IKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            complement(20368..20853)
                     /locus_tag="VUX16_000648"
     CDS             complement(20368..20853)
                     /locus_tag="VUX16_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET8123658.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            complement(20929..21210)
                     /locus_tag="VUX16_000649"
     CDS             complement(20929..21210)
                     /locus_tag="VUX16_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET8123659.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            complement(21233..22690)
                     /locus_tag="VUX16_000650"
     CDS             complement(21233..22690)
                     /locus_tag="VUX16_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET8123660.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKSTVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            complement(22821..23444)
                     /locus_tag="VUX16_000651"
     CDS             complement(22821..23444)
                     /locus_tag="VUX16_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET8123661.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            complement(23495..24481)
                     /locus_tag="VUX16_000652"
     CDS             complement(23495..24481)
                     /locus_tag="VUX16_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET8123662.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVNAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     ANRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            complement(24500..25324)
                     /locus_tag="VUX16_000653"
     CDS             complement(24500..25324)
                     /locus_tag="VUX16_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET8123663.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQTQKDLENRKRKAKKKAQKTK"
     gene            complement(25299..25670)
                     /gene="rnpA"
                     /locus_tag="VUX16_000654"
     CDS             complement(25299..25670)
                     /gene="rnpA"
                     /locus_tag="VUX16_000654"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET8123664.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGGLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            complement(25819..27009)
                     /locus_tag="VUX16_000655"
     CDS             complement(25819..27009)
                     /locus_tag="VUX16_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET8123665.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPKKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEVAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            complement(27060..28013)
                     /locus_tag="VUX16_000656"
     CDS             complement(27060..28013)
                     /locus_tag="VUX16_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET8123666.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            complement(28074..28661)
                     /locus_tag="VUX16_000657"
                     /pseudo
     CDS             complement(28074..28661)
                     /locus_tag="VUX16_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(28798..29211)
                     /locus_tag="VUX16_000658"
     CDS             complement(28798..29211)
                     /locus_tag="VUX16_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET8123667.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            complement(29189..29650)
                     /locus_tag="VUX16_000659"
     CDS             complement(29189..29650)
                     /locus_tag="VUX16_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET8123668.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVESNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(29613..29873)
                     /locus_tag="VUX16_000660"
     CDS             complement(29613..29873)
                     /locus_tag="VUX16_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123669.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(29878..30282)
                     /locus_tag="VUX16_000661"
     CDS             complement(29878..30282)
                     /locus_tag="VUX16_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET8123670.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQMISNGGQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(30275..30601)
                     /gene="comGC"
                     /locus_tag="VUX16_000662"
     CDS             complement(30275..30601)
                     /gene="comGC"
                     /locus_tag="VUX16_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HET8123671.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKEDGRITEEQAKAYKEYNDKNVGA
                     NRKVYD"
     gene            complement(30603..31619)
                     /locus_tag="VUX16_000663"
     CDS             complement(30603..31619)
                     /locus_tag="VUX16_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET8123672.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGESFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(31567..32508)
                     /locus_tag="VUX16_000664"
     CDS             complement(31567..32508)
                     /locus_tag="VUX16_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET8123673.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAVKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(32584..32949)
                     /locus_tag="VUX16_000665"
     CDS             complement(32584..32949)
                     /locus_tag="VUX16_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET8123674.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(33100..34157)
                     /locus_tag="VUX16_000666"
                     /pseudo
     CDS             complement(33100..34157)
                     /locus_tag="VUX16_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
     gene            complement(34320..35471)
                     /gene="nagA"
                     /locus_tag="VUX16_000667"
     CDS             complement(34320..35471)
                     /gene="nagA"
                     /locus_tag="VUX16_000667"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET8123675.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(35624..37441)
                     /locus_tag="VUX16_000668"
     CDS             complement(35624..37441)
                     /locus_tag="VUX16_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET8123676.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPSYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHRMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(37539..38681)
                     /gene="tgt"
                     /locus_tag="VUX16_000669"
     CDS             complement(37539..38681)
                     /gene="tgt"
                     /locus_tag="VUX16_000669"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET8123677.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            38811..39668
                     /locus_tag="VUX16_000670"
     CDS             38811..39668
                     /locus_tag="VUX16_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET8123678.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(39696..40339)
                     /gene="pcp"
                     /locus_tag="VUX16_000671"
                     /pseudo
     CDS             complement(39696..40339)
                     /gene="pcp"
                     /locus_tag="VUX16_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(40446..40805)
                     /locus_tag="VUX16_000672"
     CDS             complement(40446..40805)
                     /locus_tag="VUX16_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET8123679.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKDLLGVFLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            complement(40816..41154)
                     /locus_tag="VUX16_000673"
     CDS             complement(40816..41154)
                     /locus_tag="VUX16_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET8123680.1"
                     /translation="MTRYQILLFLLEHSLCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            complement(41560..42702)
                     /locus_tag="VUX16_000674"
     CDS             complement(41560..42702)
                     /locus_tag="VUX16_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET8123681.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPEHSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(42868..43488)
                     /locus_tag="VUX16_000675"
     CDS             complement(42868..43488)
                     /locus_tag="VUX16_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET8123682.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(43492..44772)
                     /locus_tag="VUX16_000676"
     CDS             complement(43492..44772)
                     /locus_tag="VUX16_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET8123683.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(44833..46317)
                     /locus_tag="VUX16_000677"
     CDS             complement(44833..46317)
                     /locus_tag="VUX16_000677"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET8123684.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALRERLAA
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNDAVKTAELMNALNTQGQYELTDFDAEILELFVAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVCHKTTVAAADMQVAVEAYLGL"
     gene            complement(46393..47670)
                     /locus_tag="VUX16_000678"
     CDS             complement(46393..47670)
                     /locus_tag="VUX16_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET8123685.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFSLNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(47932..48408)
                     /locus_tag="VUX16_000679"
     CDS             complement(47932..48408)
                     /locus_tag="VUX16_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123686.1"
                     /translation="METRNEKFRRLSEARMTKVFSILNILRNQSDKSKYSFSEADIKE
                     LFGALEQKGEEIKEFFTSPITIKTVNLKQEFNYSSTDTSNDKEVYFKKLSTARVEKIF
                     SLMNLLTNLSNKSNYSYNDWEIEELFTAYDEEVKKCKVFFEEKRTVFKYSEQAIKY"
     gene            48562..48843
                     /locus_tag="VUX16_000680"
     CDS             48562..48843
                     /locus_tag="VUX16_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123687.1"
                     /translation="MFKELIEFVNSSTEGQFKAFQVKANAITGDVIISQNVTPITDAL
                     KNRLGLKTVQTSLARKLAYASTRRHYKDGTTMMEDILAGKTRRHANSYI"
     gene            48905..49147
                     /locus_tag="VUX16_000681"
     CDS             48905..49147
                     /locus_tag="VUX16_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123688.1"
                     /translation="MKSLYKYLFYLFFIGFAGTLCYVLLLTNAFSPIFEAATILMEII
                     VVIFLIICIDLIASPTGSAEENIKNENVKSNNPCEE"
     gene            49110..50474
                     /locus_tag="VUX16_000682"
     CDS             49110..50474
                     /locus_tag="VUX16_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001242574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HET8123689.1"
                     /translation="MRMLNQTIRVKSKYPYLIRPRNITITRLSIQVFLFLLLVSSWLA
                     AIPFIARLVFSMFFISLLFLVERFFHSDVIEKLRNKLNIREALFYMLISLTLYDDIDN
                     EVVDTAVLYFDVSENDKVIICVPLFGNRYLKTLKNLEEYLCPTLGLSLIFKKEEIDKI
                     VYVLGKIEEIEQYVFNTNTLTREFFKDIPSPIIKLSNTQQFSLKSNTNIGIYGRTGTG
                     KTIALQWYLFNALAKGCGTVDGTYLGIVDGKGADLYALGKLLEEEIGNQVTVGTSPTS
                     LAKLSREFVEIMNERFEVIKQNSSLNADAYDLGMIPNFLFVDELASIRDSCCGSSKQA
                     KELWNEILQNLGLIARKGRQAGCHLVLSTQDPNAENIPVELRNQISAVLYLGGPGADR
                     LKMAFSMCELENVPTVSDRKGEALFYADGLNSVEPVLTIVPFVDVKTKQEFLQIVKNI
                     LPNY"
     gene            50572..50886
                     /locus_tag="VUX16_000683"
     CDS             50572..50886
                     /locus_tag="VUX16_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123690.1"
                     /translation="MKLNDFLKPELLGNRFFAVKGYTEVLDRETNKPVALRLNVSIQD
                     ENSDFFMEMIQVKINTLSPTASVQEMANNKTCPVSLKDLNVGQFNGNLWFACSDVLPV
                     TK"
     gene            50920..51309
                     /locus_tag="VUX16_000684"
     CDS             50920..51309
                     /locus_tag="VUX16_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006268423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123691.1"
                     /translation="MQTFNYDDFKNEKGIVSFSEAEQIYSSLLNSSNQLDKEFQEEWT
                     TFVLLCVEYASARGKWLTLSREEKLANDESRTVTHNKVIYQLKILKGLASEQGNDVAW
                     FEQFNDDRKRIGDFACYVAYIYALNAR"
     gene            51476..52243
                     /locus_tag="VUX16_000685"
     CDS             51476..52243
                     /locus_tag="VUX16_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET8123692.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIDVINLIGNHDAYYLLGEQAPFSIQNLEVFFAV
                     KELLQDLKLQVAYQLDDYLVSHAGFNLIFDPKEWHFNLYTKEHEEELDILAYTIGPMR
                     GGKALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHFEVISTDWATDKILKQLPRL"
     gene            52429..53208
                     /locus_tag="VUX16_000686"
     CDS             52429..53208
                     /locus_tag="VUX16_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HET8123693.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTDIKSKEKLQR
                     RTFDELTPEEQEQRLERMKKTRLEAKWNLLRLVDCNYDDNTSFLTLTTKENISDRNHF
                     KDLLKTFIKRFNYHIFNTKKSKLKYLTVLEKQKRGAWHAHILLFSVPYVPHRQLLELW
                     EHGAVRINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDRFY
                     TYEDFNYDSSVVLYETEYISKVYKDGQYFDNHVKYKKIKLD"
     gene            53225..53428
                     /locus_tag="VUX16_000687"
     CDS             53225..53428
                     /locus_tag="VUX16_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HET8123694.1"
                     /translation="MIATVTKNDLVALGFSEGTSKRIIRQGKELLITRGFTVYQNKRI
                     GTIPATIVSELLGFDVQNSTLKE"
     gene            53432..54565
                     /locus_tag="VUX16_000688"
     CDS             53432..54565
                     /locus_tag="VUX16_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET8123695.1"
                     /translation="MAIRKGKDGNWIVDISNGFDPITLKQRRIVRKGYKTKKEAIEAE
                     HYLRSVELKERFYGAKITIPILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     YNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYTSN
                     PANLIKKLPIEKTKMQFWTVKEFQHFLTLFETEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFTSNTIHITKSVYVNKGISHVSTTKTKAGTRRIIINKKLSHELQQWQQKQKHL
                     LEQFTSDSMTLQVFQGSPITITKNAVEKQYKKILERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            54606..55043
                     /locus_tag="VUX16_000689"
     CDS             54606..55043
                     /locus_tag="VUX16_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET8123696.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVDSFVATDEE
                     KAAAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            55259..55495
                     /locus_tag="VUX16_000690"
     CDS             55259..55495
                     /locus_tag="VUX16_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET8123697.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAFIEKI
                     EDMYDIKVADEAYKKWVECSKKSISHEEMMRRYG"
     gene            55488..56219
                     /locus_tag="VUX16_000691"
     CDS             55488..56219
                     /locus_tag="VUX16_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET8123698.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEKL
                     NYIFKSNANNFETDVRNEIKNNIKFNPFINWFKKRYRDERYYETETQIFVHAGIDEEA
                     EKLWKELTSSEIFTNKFLITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYFI
                     DGDVTNSKTIPVLYYDTITQKYHFL"
BASE COUNT        17311 a        11758 c         9867 g        17285 t
ORIGIN      
        1 aagattatac cacattgtgt actatttttg gttcatttta ctatatttga agaggcgttt
       61 aaactatctg acataaaact cgttctagag gaaagacatc ctttaaaaag ttagtttatt
      121 ttacaactta gacatcaagg taggttaacc ccttcatgga aaaatcaaga ctcttagcac
      181 tatgggttaa actaccactg gagacgtaat caatcgctaa accacgaaaa cggctaatag
      241 tggtcatatc aatatttcca gaacattcaa tccgagaacg tcctgcaatt agggtaatgg
      301 cctgttcaat ctgttccaat gacatattat ccaacatgat aatatcagca cccgccgccg
      361 cagcttcttc ggcagcagca aggctttcca cttccacctc gaccattttc acaaaaggag
      421 cataggcacg cgcttgagca attgcctttt gaacactacc tactgccgca atgtgattgt
      481 cttttagcat gatagcatct gataaattaa agcgatgatt atagccaccg ccaactctca
      541 cggcatattt ctcaaaaaga cgtaaattag gagtagtttt tcgagtatca aataccttaa
      601 tgcaatcatc gcctaaggct tctacataag cagctgtcat cgaagcaatc cctgataaat
      661 gttgtaaaaa attcaaggca acgcgttcac atgttaagag acttctcacc gagcctatga
      721 tttctaaaac caaatcgcca ctagtcaaac gatccccatc cttaaattga tgaggattct
      781 ggaaggtcac ctcggcatca aatagggtaa aaaccctttg aaaaacggtt agtcccgcta
      841 aaacaccagc ttccttggca aaaagcgaca ccttggcttg gccatgatga tcaaaaatgg
      901 cattggtact gtaatcttcg gaatgaacat cttctcgcaa ggctgctttc aatgtatcat
      961 ctatttgaaa aggggttaaa tcagttgaaa tgattgacat cactaagtcc tctattttta
     1021 atatcacttg taagcactag aggcaattac tattaacttc cataggaaat cacaagcctg
     1081 aatacctcat ttttaattct aacaagtgtc aatacaattg tcaagacaat tgtatttttt
     1141 tgtgtataat agtcaagtac caataggaaa caggtggtct tttgagcgcc aaaattgcca
     1201 acctatttcc atattctaac tgaaaggaca attcaatgat tcatttaata atgattagcg
     1261 ccattgctct agccattgga attggttacc gcaccaaaat caatattggc ctgctggcta
     1321 ttgctttttc ttacctcatc gcaaccactc tcatgggatt aagccccaaa gaacttcttc
     1381 atttttggcc aacctcactc ttttttacca tttttagcgt ctctctcttt tataacgttg
     1441 caacaactaa cggtactctt gatgttttgg ctcaacacat tctctaccgc acacgcaccc
     1501 accctaacgc cctctacatg attttatacc tgatggcaac ccttttgtct gctttaggtg
     1561 ctggattttt cactactatg gccgtttgct gtcctctagc gattaccctc tgtcaaaaag
     1621 cggacaaaca ccctttgatt ggagctcaag ccgtcaattg gggagcttca ggaggggcta
     1681 atttgataac cagtagctca ggcattgtct ttcaaggcct gtttaagcaa atgggatggg
     1741 aagagcaagc tttttcactt ggcaatcata tctttatcgt cagcattatc tacccactca
     1801 tcgtcttgct tttattatcc tgttacagtc actatagtaa gggaagaaca aactcatcct
     1861 tgactattga ccaaccacca ctcctcagca aggttcaaag acaaaccacc ttgctcatga
     1921 tcagcagcat ggttttggtt tggctttttc ccttgttgca tctcattttc ccaaacatcg
     1981 cctggatagc tacttatcga aaaacatttg atattggctt tgtctcaata ctcatggtct
     2041 gcctcgcctt aaggctcaaa ttagggaagc aagaagccat tttggctaaa gttccctggg
     2101 ctacaattat catgctctgc ggcatgagct tactaatgtc tctagcggtc aagtcaggtt
     2161 tagtcacact gatagggcac ctcatgacaa catccattcc tcatttctgg ttacctctgt
     2221 tcttttgtgt gatagccggg gtgatgtcac tctttagttc caccctatcc gttgtagctc
     2281 cagccctctt tcccatcatt gctatcatca gtgctcaaaa tcctcagatt gatattcact
     2341 tactcacaac agccaccgtt attggcgctc tatctactaa tatctcaccc ttttcatcag
     2401 ctggttctct cattcaactc tcacttccca atatagagga acgcggcctt gccttcaaaa
     2461 agcaaattat tctgggtgtc cccatcagct taagtttggg actcttgacc acctggattc
     2521 tcatccttct agcttcctta agttagattc attatctaac ttaagggtgg acttggtata
     2581 ataaagtaga cacaaaatta agtggaaacg aggaaaagtc attatgccaa gaaaaacctt
     2641 tgataaagcc ttcaaactct ctgctgtaaa cctcatcctg taaaaataat tagttcaact
     2701 ttaaaaattc atcccaatag tctttatcga tggattcaag aatatgaaaa atatgaagaa
     2761 agtgcgttcc caggacatgg gagcgcactt cgtcatactc aatttgagat gtagtgaaat
     2821 gaaataagaa caggacaaat agatcaggat agtcaaatcg atttctaaca atattttata
     2881 agtagatgtg tactattcta gtttcaatct actatagtaa agttgacttt cctgtaccat
     2941 ttttaccagt aattaatgtc acgtctgaac tcgaagtatc aaaagaaata ttatcaaaca
     3001 atatacgatg atccacccta tacgaaatat tttctacttt cattttttct ccttttgaac
     3061 taatagcaaa agaaacagtt ctgttttcat actctttccc cttcatctat attattcgta
     3121 atgaaaaata aaaaaataaa atttttttaa atgattatga ttcagaattt gtttaatata
     3181 ttaaaataat atataagcaa ataaattggg agattgaaat tcatttctag caatttgtta
     3241 gaagtcacag tctactattc taaccacagt atactatatg tgttacaaga aaagactcaa
     3301 aaacttctcg tcagtgtaag aatgtttgaa acactattta aaactaaata actataagaa
     3361 gtagatcagg tgaacaattt cagtacctac tctataagct atacgaagat atttttcaac
     3421 atgatggata aaacgatcac tcttttaaag ccatcttatt tagaaaagag aaaccattta
     3481 agcatagatg ggaccttctt gccctgtttt aaatttttct taaactagag tctgtaaaag
     3541 attggcttca ttttcacatt ttctcctagg aggaatgtcg taatgcaaaa gaattaaatt
     3601 caaataaatc atagcgatga cgactaatcg agtactcaaa cggagttccg ttatccaaat
     3661 aagccacttg ttctacttca aataccggtt ccgttggaag gagctgcaag taatattgct
     3721 cattttctga actagaagaa gctcgtaaga tttttgtagc actggcaata tgcaatccta
     3781 actttccttc aatgtaattg taaatcgatt tttgtaaaat atcttcagta atacctggaa
     3841 taacatcggt actcatataa gtttgttcca gaacataagg tttaccgtca ataatacgca
     3901 ggcggtaaat attataaact ggactctgca aagcgacctg tagtttttct gctaaaaatt
     3961 catttgcaaa ttctaatttg aagtgaataa tcctcgagtc aattgtagaa tgagcatctt
     4021 cagatatttt tgtcagtccc cggatatctc tttctggaac gattaatttt ctttttgagc
     4081 tgccacgaga gagaacaaag gttccctgcc cacgttttct aaaaattaag ccctcagaaa
     4141 ctaacaagtc taaagctttt ttgatcgtca ttcgactaca ggcaaactgt ttagctaatg
     4201 tcatttcatc aggcaattgt tcgttcatgg tatatttatt acaaagaatc ttttcacgaa
     4261 tctcattgta aataaataaa tattttgtac tcatttaatc tggttctctc tataatattc
     4321 taatagtagt ataacaaagt tcaagaaatg aggcaaacac aagatatgta tcaacaattt
     4381 ttaaaaatgt ctagacaaat tttaaaatta tgctatactt tatgtatagg ataatagaaa
     4441 ggaggttgag catgaaaaaa aagttagtat ttcctaatct gttttggtgg ggagctgctt
     4501 ctagcggacc tcagacagaa ggtcaatatg gaaaagtaca tgaaaatgtg atggactact
     4561 ggttcaaaac gcatccagaa gattttttcg ataatgtcgg acctcttgta gccagtaact
     4621 tttttcatac ttacaccgaa gatttccact tgatgaagga aattggagtt aattctttcc
     4681 gcacttccat ccaatggagt cgactcatca agaatttaga gacaggtgag cctgatccaa
     4741 aaagtattgc tttctacaat gccatcattg aagaagctaa aaagaaccag atggatcttg
     4801 tgatgaattt acatcatttt gatttaccag tggaacttct tcaaaaatac ggtggttggg
     4861 aaagcaaaca tgtagtggag ttattcgtga agtttgccaa gactgctttc acatgctttg
     4921 gagataaggt tcattactgg acaactttca atgagccaat ggtcattcca gaagcaggat
     4981 acttatatgc tttccattat ccaaatctaa aaggaaaggg aaaagaggcc gtacaagtca
     5041 tctataatct aaaccttgct agtgcaaaag tgattcaact atatcgctca ttaggacttg
     5101 atggaaagat tgggattatt ttaaacttga cacctgctta tccaagaagt aattctccag
     5161 aagacttaga agcaagtcga tttacagaag acttctttaa caaagtcttc ttgaatccag
     5221 ctattaaaag gaactttccc agaaagattg gtaaaacagc tagagagaga tggcgtgtta
     5281 tggagtcata ccgaaaaaga gcttcaactg atgaaatcaa atacggttga ttttcttgga
     5341 gtaaactact accatccaaa acgtgttcaa gcacaagcaa atcctgagga atatcagacg
     5401 ccctggatgc cagaccaata cttcaaagag tatgaatggc cggagcgtcg catgaatcca
     5461 tatcgtggtt gggaaatttt tccgaaagcc atttatgata ttgctatgat tgtgaaggaa
     5521 gaatatgata atattccatg gtttatcagt gaaaacggaa tgggtgttga aaacgaagca
     5581 cggtttatcg gtgaaaatgg agttatcgat gacgtgtatc gtattgaatt ttatgaagaa
     5641 catttaagat ggctacataa agccattgaa gagggaagtc actgttttgg ataccacgct
     5701 tggaccgcat ttgattgctg gtcttggaat aatgcatata agaatcgtta cggatttatc
     5761 tccgttgatt tagaaacgca aaagagaacc atcaagagct caggaagatg gtatcgcaaa
     5821 gtaagtgaca ataacggttt tgaagtagaa attgaggagt aaagagagga gatattcaga
     5881 tgaaaaactc aaaatttata gatcaatttg ccacctttgc tggtaaacta gggaaccaaa
     5941 ttcatttaaa aaccctaaga gatgcattcg taacagtaat gccattatat atttttgcag
     6001 gtttaatcgt tcttttgaac aacacggtat ttaagtggat tttccaaggg gatacattaa
     6061 caagattcca atattgggga ataacaattg caaacggtac tttaagtatt tcaggtatga
     6121 ttattgctgt aatggttggt tatttcttag ctaaaaacag agatttcgaa aacccgttag
     6181 cagcatcaat gctatcatta gtttctttaa ttgtgatgat gccaaataca gtttctgtag
     6241 ttcctgacgg agcaaaagat gcggtaaaca tttcaggtgt tctttcattc aacaacacag
     6301 gtacaggcgc aatgttcgcc ggggttatcg tagcgattat tgcaacagaa ttattcattg
     6361 aattatcaaa cgttaaagct ttacaaatga accttggtga aaatattcca ccagctgtta
     6421 gtagatcatt tagcgtatta cttccagtca tgaccgttat ctccttattt ggggttgttt
     6481 cagcattatt attcaatata actggaatga acttaatctc aatcattaca atctttattc
     6541 aagaaccaat tcgtcatatt ggtacaagct taatcggggt cattattatt tactctttag
     6601 gaaatatgtt atggctattt ggtattcacc aagcagttat ttacagtgcc atcctagaac
     6661 cattactatt aattaacatt actgaaaaca tcactgcagc aaataatgga caagccattc
     6721 cacacatcat caacctatca caaatacaaa cattcacttt aatgggtggt agtggatcta
     6781 cattatgttt attaatagca acattcttag tgagtcgcaa tgctgtctct aaaaacgtgg
     6841 ctaaattatc ttttggacct ggtatcttca atatcaatga accagtatta ttcggttacc
     6901 caatcgttta taacatttca ttagctattc catttatcac agttccagtc cttggtattt
     6961 taatcagcta cttagcaaca gttacaggat tcatgagtcc tgcatttata caagttcctt
     7021 ggactacacc agtattctta aatgcatggt tagcaacagc aggggacgtg agagcagttc
     7081 tagttcaatt catcatcttt gcacttggag ttcttctata cattccattt atcaaagtta
     7141 atgacaaagt tgttgaacaa gaaatggaag gttaagatta tgaaacaaat tttattagta
     7201 tgtaatgcgg gaatgtcgac aagtatgctt gttaaaaaaa tgcaacaaag tgcgactgaa
     7261 cgtgggattg aaatttctat ccaagcaaaa tcaatgacag aagctaaaaa gaatatccat
     7321 gaagcagatg tcattctaat tgggccacaa attcgttatg agttacttgc tgtgaaagaa
     7381 attgcaggaa atatccctgt agataccatt aatatgcggg attacggaat gatgaatgga
     7441 gcaaaagttc tggaacaagc acttgcatgg ataggagaaa taagatgaca gaagaaatgg
     7501 aatatatctg ttttcagctc attgccaata gtggagcagc caaatcatcc tttattgaag
     7561 ccatccaact agctaaggca ggaaatttaa aagaagcgaa aattaaagtt gaagaagcgg
     7621 aagactcctt agtagaagcg cacaagattc actctaatct catacaaaaa gaagctactg
     7681 gagaaaaaat aggattctcc ttgctattta tgcatgcaga agaccaaatg gcttcaacgg
     7741 agattattca gttgctatct aaagaattca tcgatctcta tcaaaataaa taggaacact
     7801 gtcgttccca tctgtcttta ttaatgacgg ctacattata ggaacctcca aaagttggac
     7861 aaaatgattg aaaggattgg atcctgcatt acacaagatc caatcctttt cttttactct
     7921 agtttttata atatgttgaa tctagaatag tccactgtag tttctaaaaa attgctggaa
     7981 atggatgtta agctccaatt tatttgttta tatcttattt cagtttacta tactagctta
     8041 ttattctagt gaaaaattga atgagccact atttatttaa tatgtatgat gagggaatga
     8101 ctcaaaaact tcttgtcgat ataagaatat ctgagatagt attttaaaac gaaaggacta
     8161 taaaagctca tttccttcgc gcttatttta tagagatcta tcattatact ctttagaaat
     8221 caaaaagcaa cacaccttgt catcgttttc tcgttttctc gtttgctctt tgattttaat
     8281 tgggccttag taaatactac tcttaaatta aactatagtg aattgaaata agatgtgaac
     8341 aactctatca ggaaagtaaa attaatttct ataaatgttt tagcaattgt ttcgtactat
     8401 tttagattca ttttattata ctatattttt tatatagtat agtaaaatga aataagaata
     8461 gaataaatcg atcaggacag tcaaatcgaa ttctaacaat gttttagaag cagatgtgta
     8521 ctattctagt ttcaacctac tatatatttt gtttctattc tagtttttca aaaagggcaa
     8581 aaaggcctca acatcataaa aaggcatcct atcaggtatt caaaaacctt gataggatgc
     8641 cttttatcat agaaaaatta ctggttcttt ccctcaaatt gagtttttgt cttgcttcta
     8701 gactgataaa caattattta cggcgccctg gtctttcttt gtagccatag tatgcatctt
     8761 cgatgatttc ttgcatatgg tctaccattg gaagacgtgg gttagctggt gaacattggt
     8821 cttcataagc caggaaggct aattcacgag aatgttcttt ccattctttt tcgtcaattc
     8881 cttggtctct aaaattcatt tggatcccaa tacgttcacc gagttcgtag acagcttttg
     8941 cgtaagattc aaccccttct tctggagtag aagctggaag tccaagcatg cgtgcgatat
     9001 cttggtattt ttcatctgca cggtagtagt tgtacttagg ccatgttgct gtcttagctg
     9061 gacgtgtacc gttgtaacgg ataacgtacg gaagcaagat ggcatttgta cgtccgtgaa
     9121 ctgtgtggaa ttgcgcacca atcttatggg ccattgagtg agaaatacct aggaaggcat
     9181 tggcaaaggc cataccagcg attgttgaag cgttatgcat tttctcacgt gagtggaagt
     9241 ctgcattctt aactgagctt tcgagatttt caaagaccaa tttaatggct tgaagtgcta
     9301 aaccatcagt gtagtcacta gccatttgtg atacgtatgc ttctgtcgcg tgagtcaata
     9361 cgtccatacc agtatcagca gcaacaaatc ctggaactgt caataccaaa gcaggatcta
     9421 cgattgccac agttggtgtc aatgagtagt cagcgattgg gtatttacgg ttgtttgctt
     9481 tatcagagat aacggcaaat gatgttactt cagatcctgt accagatgta gttggaatcg
     9541 cgatgaattt agtcttctta ccaagcaatg ggaacttgaa ggcacgttta cggatatcca
     9601 tgaatttttt gacaaggtca cggaagtcca cttctggttg ctcgtagaag agccacatta
     9661 ctttggcagc atccattgga gacccaccac cgagtgcgat gatggtatct ggtttgaagg
     9721 cacgcataat ctcagtacca cggtttacag ttgtgatatc tggatccggt tctacatccg
     9781 caaagatttg gtaaacaacc ttattgcgac gaaggtccag ttgttcgatg atacgatcaa
     9841 ggaaaccaag ctctaccatg gcatggtcag taacgatcat gacacgttca acgtcacgac
     9901 atttttgaag gtattgaatt gaatcacgtt caaagtatgt ttttgaagga agtttcatcc
     9961 attgcatgtt atttctccgt cttccgactt ttttgatatt caagaggtta atggcactaa
    10021 cgttatcccc aactgagttg tgtccgtaag aaccacatcc aagtgtcaat gatggcaaga
    10081 aggcattgta aacgtccccg ataccaccaa aagtagaagg tgagttacag ataacacgaa
    10141 tagctttaac agctttacca aattctttag tcaattcttc gtcagctgtg tggatagctg
    10201 ctgagtgtcc aagaccgtta aattcaacca tttgacgagc cttagtaata ccatcttcac
    10261 ggctttcaga tttcaaaact gcgataactg gtgacaattt ttcacgagtc aatggctcat
    10321 tttcgccaac ttctttacat tctgcagcaa gaatgtttgt tccttctgga actgtaaatc
    10381 ctgcttgttc tgcaatccaa gttgctggtt taccaacgat gtcagcgttc aattttgcac
    10441 cagcacagtt tttgctgttt gctttgacgc cgaagcagaa ctcttcaaga agagcttttt
    10501 cttttttgtt tacaaagtaa gtgtggtaag atttgaactc tgctacaaat tcatcgtaaa
    10561 tttctttatc aatgataact gcttgttcag atgcacagac cataccgtta tcaaatgatt
    10621 tagacatgac gatatcgtgt gctgcttgac gaatgtttgc tgatttttca acataagctg
    10681 gaacgtttcc ggcacctact ccaagagctg gtttaccaca tgaataagcc gccttaacca
    10741 tggcattacc acctgttgca aggattgtcg caacaccttc gtggttcata agggcacttg
    10801 ttgcttccat agatggttga ctaatccatt gcacacagtt ttcaggagca ccagctgcga
    10861 tagctgcatc gcggacgata cgagctgcat gagcagatga ttcttgtgct gatggatgga
    10921 aggcaaagac gattgggtta cgtgtcttca atgaaatcaa tgatttgaag attgctgttg
    10981 atgttgggtt tgttgttgga gtaataccac aaacaacacc aactggttca gcaataagag
    11041 tcaatcctgt tacatcgtct tcttcgataa cgccaactgt cttagtgtgg cgcatgttgt
    11101 ttactacgtg ttcacaggca aacaagttct tagttgcttt atcttcaaat acaccacgtc
    11161 ctgtttcttc aaaggcatgt aaagccaatt ctccgtgggc atccaaagct gctactgatg
    11221 ctttggcaac gatgtagtca acttgctctt gatccaattt acgcatttct tcaagggcaa
    11281 ctagagcttt ttgaaccaac tcatctacgt gtttttcagc aacgagtttc ttttcctctg
    11341 gtgtcacagt ttttttatca gccatatttt cctccatagc tttcaaggat cgatatcctt
    11401 tgttaatttt ttcacaagtt tattataacg cattatttca actttgtaaa cagtttcata
    11461 aacatttcac aaagaatttt taaactcttg tgaaactttt ctcattttct tttcttatca
    11521 ggttttatct ttgaagtttg tgaaatttat ttcaaatatt ttttatttca caaacttgct
    11581 tggaagaggg atttggaaag aaaaggattt gcaagtaagc gcttacttaa aacttctaac
    11641 aatacctcct ttgataagga ggctttattt ttgttgaaaa acgccttgtt taaaagtccc
    11701 ttcataaaca acttcttgtt ctgttgttag ttttcctttt ccttcagcct gaccatttac
    11761 aaaatcacct tcgtaggtcc aaccttcttt agattgaaaa gtaccttttc cattgaaggc
    11821 tccattgttg aagccacctg tatattggtc tccattttgg aaggtaatgg taccttgtcc
    11881 attcatttta ccacggacaa gactgccgtc gtaaacaatc gttccattat cgagttttag
    11941 aatacctttt ccgggaatat ttagaaaaaa gacgagtaca gcacaaaaaa caatggtaac
    12001 tactgctaaa agctctaaac gtggacgagt cagatagaca cgatactttt cataaaaact
    12061 cttaagattt tccatcttca ctctcctttt ctaaacgttc taaccaaact ttacaaccct
    12121 cctggacacg ctgataggtt tcctcaaaat ctcctgtata ccaaggatct ggaacacttt
    12181 cagatgaaaa tgagtaaatc ttatcttgac agtctactgg acacatctga cgtaagtcgg
    12241 aaacatttga agcgtccatt ccgataatat aatcaaaggc ttcaaaatct tccttactaa
    12301 tctgaagcga tgtcttgttc ttgtcataag gaatctcata ctgttgaaaa attccctgag
    12361 tccccttatg aatcggattg ccatgttccc aagaggaagt tgctcgactt tggatttcgt
    12421 agttatctgt cattgatttc ataacaaact cggccatagg gctacggcaa atatttccta
    12481 gacagacaaa gactaatttt ttcatcccat ttcctttctt ttatagaaaa acgggagttc
    12541 gtgatcccgt cttatttttc aattgcgcct tctagtgaag ctgtttcttt cagcggtaat
    12601 actgtcttga tagcagctag ttcaaaagtc aagtaaactc catctacgtc aagaactatt
    12661 gttcccttct ccgtatctac ttcatcgact gttccataaa gtccaccgat tgtaatcact
    12721 tcatagcctt tttgtagttt atttaagctt tccatacgtt tttgtgcttg tttcttttga
    12781 gagcgttgcg taaagaatat caagcccacc ataagggcta gcatgattaa aaatgtataa
    12841 tttggattca ttgtcttctc ctttgtcttt tacataggac tactatatca aatttcggct
    12901 acttttacaa gattgtacct tacttttctg gtaagaaaaa ccagagcttg cgccctgatt
    12961 tttaggatta tttcaagttt cgaacaactt ttacaagatt ttctacagta aagccatatt
    13021 ctgccaatac ttttggtgct ggggcagagg ctccgaaggt atcaatacct agaacggcac
    13081 catcgagacc aacatatttg taccagtttt gacttgcacc catttcaatt gcaacacgac
    13141 ggcggactgc atttggaaga atttcttcct tgtaagctgc atcttgttta tcaaagacat
    13201 ctgtagatgg aatgctgact acgcggattt tttcgccttg actagccaat tctttagcag
    13261 ctgagacagc aagattaacc tctgaacctg tcgcaatcaa gatggtatca aagtcggctg
    13321 cattttcata tacaacataa gcacctttag caaccttgtc gaagtctgtt ccatcttcaa
    13381 cagtcaagtt ttgacgtgtc aagacaaggg cagttggtgt tttctcactt gtcactgcaa
    13441 ggtaccaagc tgcttgagtt tcacgcgcat ctgctggacg gaaaacattt agatttggca
    13501 tagcacgaag acctgctaaa tgctcaactg gttcgtgagt cggaccatct tccccaactg
    13561 cgattgaatc atgggtaaag acataagtca caggaagtcc ttgtaaggct gacaagcgga
    13621 cagctgcctt cacatagtca gagaagacga agaaagttcc accgtataca cgaagtccac
    13681 catgaagggc catcccgttc aagattgttc ccattgcaaa ttcacgaaca ccaaactgaa
    13741 tgttacgatt caagcgattg gcatcgtctt gaagtccatc cgtcttgata taagtcatgt
    13801 ttgagtgagc aaggtcagct gatccaccta ggaaggttgg taatttagct gccacaacat
    13861 tcaaggcatc ttgacttgaa ttacgagttg cttgagaaaa accattttct aaagctggga
    13921 agtctgctgg agtcacttcg actggatcac gtccgtcgat gatggcttct acttctgcag
    13981 ccagttccgg atgagcttct ttataatctg caactaattt agtccaagct tgataagctg
    14041 atgcgccacg gtctgcaaca tgttctttga aatcagcata tacttgttct ggaatttcaa
    14101 atggttcgta gtcccaaccg agggcttgac gagttgatgc agtttcatct gctccaagag
    14161 gggcgccgtg tacagcatta gttccttgtt tgtttggaga accgtatcca ataaccgtct
    14221 tcacttcaat caaagatggc ttgcctgaag cttttgctgt ttcgatagca gcatggattg
    14281 cttccaagtc tgttccattt tcaaccaagg cagtatgcca accgtaggca ttgtaacggt
    14341 cacgaacact ttctgtaaag gaatcctttg tctcaccatc caagttgata tcatttgaat
    14401 cataaagaac aaccaactta tcaagttttt gcaagcctgc gtatgaagct gcctcgcttg
    14461 agacaccttc catcaagtct ccgtctccac agataacgta agtatagtgg tcaaagatat
    14521 tgtagccttc acggttatat ttagctgcca agaaacgttc tgcttggaca aaaccagtag
    14581 cagttgaaat cccttgccct agaggacctg tcgtagcatc aatccctgcc gtatgaccaa
    14641 attctgggtg acctggtgtt tttgaacccc attgacggaa gctcttaatc tcatccatgc
    14701 tgacatcttc aaaaccagaa aggtgaagaa gagcataaag gaacattgaa ccatgaccag
    14761 ctgaaagaat aaaacggtca cggttaatcc agtttggttg agctggattg atacgaagtt
    14821 gttttgtaaa gaggctgtaa gccatcggag ccgctcccat aaccacacct gggtgacctg
    14881 agttggcttt gttgatagcg tcaataccta ggaaacgaat tgcattaaca gatagatttg
    14941 acatagaatt tcctttctat ttgaggtgat tattgaatca cacattctat tttactatta
    15001 tatgaaaatt atccgtatgt tgcaacatac ggataacctc caaagaatat ttttatatta
    15061 taacaaagct ttaaattgaa tgttagagtc ttgttcaaaa caatcatcaa aaccacgtgg
    15121 atgatggtat tctactaagt gttgatcttg aggataagtg tacttaccgc caacttccca
    15181 gataaatgga tggaaatcgt attgcaagcg atcttttcgc attttccaaa gttctagaat
    15241 ctcattagta gaagccatga agttagacca aatatcatag tgaactggga taatgacttt
    15301 ggtacgcaga ttttctgcca tacgaagaag gtcgatagat gtcactttgt cttggatacc
    15361 taccggattt tcaccatagt tattcaaagc aacatcaatt ttaaagtctt taccatgttt
    15421 tgcaaaatag tttgagaagt gagaatctgc accgtgatag atggttccac ctggtgtttc
    15481 aaagatatag ttaacagcct tttgagccat ttcctcatct gtaacagcta agccagcaag
    15541 ttcaccgcct gtctcatcag caccgttcac tgggagagtt accaagcaag tacggtcaaa
    15601 tgattctact gcatgaatct tcatatcttt taattcgata gtgtcacctg gtttaacaac
    15661 gatgatacgt tcttttggaa caccccatcc ttcccagatt cgtccacagt ggtaaggacc
    15721 gataaactta acatgctcta acttaggatt gttgagaatt gctgcagctg tgtatgggtc
    15781 gatatgatca ctgtggaagt gtgaaactaa gtaatagtct agttcgttga tagcaaatgg
    15841 atcgataacc attggctgaa cacgcaagtt tggttgcagc ttacgaacac ctgccatatt
    15901 tgccatttgg tgcccacgaa ccatatcttt cacttttttg gttgattttc cacggtttga
    15961 ccaaaggtcc atgacaacgt tagcaccagc tggtgtctta atccaagtac cacagttgcc
    16021 tagccaccac atggcaaagt tgccttcagg tacgacttct tcttcgattt cttcgttcaa
    16081 ccatgttccc cactctggga aagtggctaa aatccatgac tctcttgtaa tttctttgac
    16141 gtttggcata tgttgcctcc tttggatata attgttatct ttgagattag tataccaccc
    16201 ttcaaaacac taaaaaagac caagaaaaac acaggtttgt gttcatcatt ggactgtcct
    16261 tcaaatatct tccaaaaaag attaaactac tatttcttga tttataagtg tttgaacctc
    16321 ttcttggaac ttactagcca acttgctgtc tacaatataa gacgaaataa gactagaaag
    16381 attttcactg aaacttttgc tcttattacg aaatatattg tgtttaagat agtctagcat
    16441 tttcaaaata tcttctgctt caaggatagg attaaccctt aaaatcggaa atctgctatc
    16501 caaatcatca ttagtagtaa tcactacatc aacttgtgca atatcttcca cactcttaaa
    16561 ttgttctgtt gtaaatacag tgtcaatttg ctcatttgga aaataaagtt tgcattgttt
    16621 cagcaaaagt ctcgaaaccg caacaccttc atcacaaacg agataaactt ttttcatatt
    16681 tttttgagac gatggtgtat actttaaaaa tcctccaata tgaatcgtca aataggcaat
    16741 atcatcgtct gttagccgaa taaaccatgc tccttctaaa atttccgcag attttctagt
    16801 gactaaaaat aattctccat acttggatcg aatttgtttt gttagaggat ttttagaaaa
    16861 aataccgtaa gtctttctaa ataacaaggc tttacagtgg atcatcaaat ttcgtaacaa
    16921 atcatccttg ttctcaatct ccattcggat ttgtgattca aaataccaga taaattcttc
    16981 taaagcaagt tttaattgcc gaaaatcatc actttctgca tgaatatcca aatctttacg
    17041 ataggagagg aggagaacag ctacaagaga aacttcaagt cctgacaaag aaatttcaaa
    17101 cttttgaaac aaccgttctc ctaatttctt agacacctga tactctattc tttttcttat
    17161 caaagaaaat tctttctcta tatcctgatg tctttcttga tactgttcaa cattatgaca
    17221 gcttaacagc aaataaggta gaacctgcaa cataaaagtt atttcatgat gatttatttt
    17281 cttccctaaa tcttgttcaa ctaaaggaac ctgttcctta aaaaattggt tcatttcaac
    17341 agaaagcaaa cactcatcat ctaacctctc tttcatctta tcttctaaaa tagatacaaa
    17401 agtggcattt tcttccataa aaatatgata tagaagcgat tgaagatact gaattttatt
    17461 aagagggtgg gcatgaaggt ggtatccctg tgacttgctc acttgcaaga tcacctgata
    17521 ttgttccaaa gttagttgat aacgaatact attcaaatca ttgagaacag tattcctaga
    17581 tacctctgtt aactctatca atttttcaat cgtaatacgt tctttagaaa tacctatcca
    17641 tagtaacatt atcatcatac gttcatgcgc actcatgata taatcgtacg aatctacttc
    17701 cgataatagt ttacaacaag catctctctg ctcttccgtt aagtgaatac caattcgtgg
    17761 aatactaatg atgtgaagcg cctcgtcacc cagagcagca ttgattttgt caatgtgata
    17821 ataaattttc cttcttgact ctttcaaatc tttcgaaatc gccataatcg ttttggacgt
    17881 ttcttgatcc atcaaatatt gaagcaaatc acaacttgcc ttatccagta ccatattaaa
    17941 aaatccccca aatctattga tatcacagca attcttttta ttttaccata tatatatcaa
    18001 gcgctatttc taaaaaatct tttaaaatta cttcaactcc aactttactc tcaataaaaa
    18061 tcaaatgtaa aaagaggagc taaatttatc tttttctcct ccttcatcgt tcttactttt
    18121 gaccataata agcatttggt ccatgtttac gttggtagtg tttttctagt atgtactggg
    18181 gagcaggtcc aactcttgga ttgatttgtt ctgtaaagcg attcatcttt gatacttcct
    18241 ctagtacgac agagtgataa acagcattct ctggattttt gccccaggtg aatggaccgt
    18301 gattgcgtac aacaattcct ggtacttcaa ccgggttaag tccgcgatgt tcaaactctt
    18361 ctacgataac caggccagta tctttttcat aggccacttc tacttcgtcc ttggtcaaac
    18421 tacgggcgca agggattgaa ccgtagaaat aatctgcatg ggttgttccg tagaaaggaa
    18481 tatcacgacc tgcctgagcc caaccaacag cttctgtcga atgggtgtga accacactac
    18541 caatttctga ccaagcctta tataattgca catgagttgg gaggtcggaa gatggtctta
    18601 aatccccttc taggatctta ccatctagat cagtcactac catgttttca ggtgtcaatt
    18661 cgtcataatc cacgcctgat ggtttgataa caatgacacc gagttcgcga ttgacttcag
    18721 atacattccc ccaggtaaat ttgacaagtc catgttttgg caatgattga ttggcatcac
    18781 agactcgttt acgcatagca ttgattactt gattcatctt acatcaaacc tgctttctta
    18841 atgagtggat agagaaaagc ttgcgcctct tgaatggctg cgcgtgtttc ttctactgtt
    18901 tcacaatttt cagaccacat ttcgattagg aaaggtccat tataattggt ttcctttaaa
    18961 atatcgaaag cttcttccca tttgacacaa ccttgcccga aaggtacatc tcggaactgg
    19021 ccctttgaac tttctgtcac tgcataagta tccttgagat ggagagctgc gatggcatga
    19081 tgaccaagat aaaactcact atagatatca ttatgccatg cagacacatt accaatatct
    19141 ggatatacaa agaggaaggg agagtcaatc tctttttcta tagccaaata tttttcgatg
    19201 ctattgatga aaggatcatc cataatttca atagcaagta ccacctgagc ttcttcagcc
    19261 cagtcacagg cttttctcaa atttttgata aaacgttggc gtgtctgggg tgccttttcc
    19321 tcatagtaaa catcgtaacc agctaattga atcgtacgaa ctcccaagtc ttgagctaat
    19381 tcgatacatt ttttcataag ttctagagat ttttcctcta gaactggatc ttttgatccc
    19441 aatgggtagc gacgatggcc tgaaaaacag atagaaggaa tacgaacacc agtttcatag
    19501 attgctttga caacttccaa gcgttcttcc ttactccagt caagtcttgc taaacgctcg
    19561 tcacgttcgt caatagacat ctcgacaaaa tcaaagccta actccttggc aaaatttaaa
    19621 cgttctagcc aagtaaagtg tgttgggatt gccttttcat aaattccaat tggacgtacc
    19681 atgatttacc cccaaattcg tttgatttca tccttgaagg cacgcgctgc tcctgctgga
    19741 tccacagcct ctgtaattcc acgacctgcg ataaaggtaa agacatcaac accttcaaag
    19801 agtttgagag tatctacatc tagaccacct gttacagata cacggaagcc catgtcaatg
    19861 agttttttaa tcttattaag gtctttttca ccccaagttt caccagcaag aagagcatca
    19921 cgagattggt gataaatagc ttgtgagata cctgcatcta gccaaagctg agcttgttca
    19981 aaagtccaat cgccataaag ctcgatctgg atttcgcctc gttctcctcg ttcagtcttg
    20041 atagccttta gagctgcttc catagtaggg atggttgcac aacagataca agtcatccag
    20101 tctgctccac gaaccgcatt atttttagca actgttccac cagcatcagc acattttgtg
    20161 tctgccacaa taatcttatc tgggaaaagg ctacgcaaga cttcagccag ttcacttcca
    20221 acttgaagca agcaaacagt tccagcttcg ataatatcta cttcctgacc aacagaaaca
    20281 gctgctttaa tcgctccttg caagtctgaa tagtctaatg caacttgtaa attaggtatt
    20341 ctttttgtca tttctttatt cctctttcta actttccaaa tccaatcctt cgagataagg
    20401 gctatcctta gattcttcaa tcatagccaa gacatcttct ttagtctggc aagcctgtaa
    20461 acgtgcaata gaatcttcta attcaaacag ggcaataatt tgtggaatgg ctacacttgt
    20521 gtgaattttt gagcttgttg ctgctagtgc caacaaaaca gatacctctt tcccatctga
    20581 aaatacaaca ggattttgta aggtaatcaa tgaaaaggca tcactttgca caccagcttc
    20641 aggtctagcg tggggcatag ccatacctgg catcaagata tagtaaggcc catactcttc
    20701 agtcgattca atgatagcat cgtaatactc tggcaaaatt gccccacttt caattaaggg
    20761 atctactgct accttgactg cttctttcca attgttagcc tctaaaccta gtcggatcga
    20821 gtcattgtca attaaagctt gttttaaatt catatctgcc tcctttattt aagagggaga
    20881 aggacagaaa cgataactct cagtttctgt ccagccccct ccaacctttt actgtagtgc
    20941 ttgactgagt ttttcggtga tttctttatc atccatcaag ttatcaagcc caattaactt
    21001 cccattagtt cgcccttcca attcttgaat caaatgaaga gaagcgatta cgatgtcata
    21061 tcctactgct aaacctttag cttcaccgac actgcatgaa ttgactgtaa aatctgtttg
    21121 attaagctta cggagagcat tttcaacctt catcttgata accattgatg aacccattcc
    21181 atttccgcac gctgctaata ctttaaccat tttatttctc cttttctaga tactaagctt
    21241 cttcttgaac ttcaccgttg taatatttct ctttatcttt tgctttggca aattgaagtt
    21301 gaggaataac aagcaagaag agacacacaa gtacataacc aacaatacca aggtatttga
    21361 agatatatcc aaatccaagc catgggaatt caaagtcgat atttccatgg tagccaccat
    21421 aagatgccaa atcgagaagg gccacacaaa gagctcctag agcaacttga aggacacctg
    21481 atataaagga aaggataaca gccgctttcc atccgccgcg tttatcagcg tagactgcaa
    21541 tggctgcatt gtcaaagaac actggtacaa atcctgtaat aataagaatc ggatttttaa
    21601 agacgatgag caaaacaatt gtaatcaatt gaccaatcaa accaaaggta aatcctgaca
    21661 agacagcatt tggagaacca aatccataag aagctgcaac gtcaaccgct gggaatgaac
    21721 ctggcaacaa tttgtttgaa ataccttgga aggcgtttgt caactcagat acgaacattc
    21781 ggacaccttg catcaaaacg aacaagtaaa ctgagaaggt aaaggctgtt tggataatgt
    21841 acataaagaa atcttgttta gcaggattga atagagttcc tgaagtgatg acttctttat
    21901 tagacataat gtctggaccc aagattaaaa gaatggctcc gaagaatacg agcatcaagg
    21961 tagcagatgc aacaactgta tcgtggaaga ttgagaggaa cttaggtaat ttaagattgt
    22021 ctaaactttc ttctttctta ccaaagcgtc ctgctacttt atctacaaac cagattgcaa
    22081 attgctgttg gtgaccaatc gcaaatccgc caccaccagt caagcgttga gttgcctcaa
    22141 cagtcatatt tgaactaact gcccagtaaa gtccacagat gataccaatc gctgctgtac
    22201 cgtaagcatt gcgcaattgt ggtactaaga atagaaccat aagagatact gttgcagctt
    22261 gttgtaccat gatgtgacca gtaataaaga gggttcttac cttcgtaatc tttcgaagag
    22321 ctacgagcaa gatatttatt ccaaaaccaa tcaatagagc tgtagttgca gttccaacaa
    22381 aatctggaaa ctctgctgca attttgttgt ttgctgcagc aagtccaaag taagggtcga
    22441 taaccgctgc accaatttgg aatttgtagt taagagctgc taagattgga cgaaaggttg
    22501 taaccaaacc accagcaccc acgttaagca acatataccc tactgttgat ttaacaaacc
    22561 ctgaaaaaac gtcatgggca ggttttttca aaagtgcata tcctatcaac accaataaac
    22621 ctacgaaaaa tgcgggattc tgcaaaatat tgctagaaaa ccaatttaga acacttgaaa
    22681 cgacttccat aattgttctc cttttgaatt gtttttgtaa gtttattata taatgcgaaa
    22741 gcgcaaacaa aaagaccaag aattacacag cggactgttc actcttggac tgtatgattt
    22801 atgatgtttt acaaattatc ttattttctc gtagctagat aatagggaag aattttagaa
    22861 taagacttca ataagccttc tacgatttct tcttcagacg aattttctgt cataggaaca
    22921 tctaccttca ctaaaacttt tcgaacttct tgactcctca ccttctcgcg taaagtacga
    22981 cgcttttctt cattcgcctc ccaccgttga ctttgaccat tagagtaggt tagataataa
    23041 atccctttaa cggttggaat gtctaaaact ttggtctgct tgcccagtgt ttgctcatcc
    23101 ttcttacgtt cgatgaaact gacttccaaa gaaattccaa agtcagtaga tgtcccatac
    23161 aaacgtaagg ccatcatagg ttctgtcact tgtccgtctc tctgtagata aacccaaaaa
    23221 tgtggtctca aacgctgggc ctgattcatc cactgactag tctgttggag ttgccattct
    23281 ggatggcttg cttgaaaggc tttggccagt tctgtaaaag cctttcgggc ctcttgtcct
    23341 ttgtggcgga acgccagcat cttctctcgc tctgctcccg ctttatcagg actacggtac
    23401 tgcaaaccag aaaagtctag atagtctctt atcttattca acatcagttt aacctcctct
    23461 aactagcaaa aaatcaggtc aaccctgatt ttacttattc tgtatctaca acaacatagc
    23521 gatttggctc atcaccttca gagtaactag tcacgccatc catacgtgaa ataatacgat
    23581 ggataatctt gcgttcgcta tttgacattg gatctgtttt atgactgcga ccttcttcca
    23641 aaacacgatt cgccaatttt tgcgcatagg tctgcaagac ttctgcacgg tgttcgacat
    23701 aatcattgac attgattgta acgtagaagg ttttggaata gcggttgtaa agataatttt
    23761 gagccaacag ttgcaaggcc ttcaagactt taccatggta gccgataata cgacctggtt
    23821 cgttggtgtc aatttgtaga ttgatgctac gacggttata atcatttgaa agtgtagctt
    23881 caacatccat gtcatccaca atcgcttgaa cataggcagt cacatccgta gccacctggg
    23941 caatatcata actttgctcg accttcaagc ccatctcttt caagtcttga ttttcagttt
    24001 gatcttgctc agtttcaagg tcatcagcgc ctgcttcttc cctcatcgct tcctcgattt
    24061 gaagttcatt taaaatctca atgtgaccag tttcttctaa gatagtgctg gcatgtcttt
    24121 catgttttaa gatttcagcc ttgacttcat cagaaatacc ttgaccttct tcctctattt
    24181 ttttaatagc attaaccaca tgaccaaggt caacggtttc ttcactaacc gtcttcacag
    24241 gctcgttcaa atcattgatt tttttcggaa cgccttttac tacctgttga tttgctttga
    24301 caacagtcgt ttcactaatc gcttcaatat ccacttgggc tggtttttta ccaaatagac
    24361 caagaaagcc ttttttctcc ctagaaatga ctttgatatg agccttcatt cttggaatat
    24421 ctaattcttt caatcctttc tggattgctt cttcaacagt tgaacctgta aatactacca
    24481 ttaccagatt cctccttatt tatttcgttt tctgagcctt tttcttggct tttctttttc
    24541 tattttccaa atctttttgt gtctgtacta cggcctcgcg ctctgcgata atcttgaatg
    24601 gattattcaa gaaataggtt tgcaagactt gataagcatt agacactgtc cagtataggg
    24661 cgactccacc tggcgcataa actgcaaaga taaaaatcaa gactggaatc ccatacatca
    24721 tcgcagtcgt agcgccattt cgctcagaca aagctttgtt ggacaaccaa gtacttaaaa
    24781 aggtgaatac tgctgctaaa atcggaagaa caagggttgt atccacacta ccaaggttaa
    24841 tccataagaa atgacctgtc tttaaaaagt caactcttga tagggcttgg aacagggcca
    24901 aaataaccgg catctgaatc aaaatcggcc aaagagagtc tgactgtctg acacccattt
    24961 ctttaaatac tttacgcatt tcctgctcta gtttggttct gctttccata tctcgacctg
    25021 gatattgttc tcgaagcgcc ttaatgcgtg gctgagcttc ctgcattttc ctagaagcca
    25081 ccatttgcac ctgaaagact ggcaagagga ctgtacgaat caagaccgta aagagaataa
    25141 tccccactcc gatactaata tcaaacgata aaaagcgaat gatttccgca aagaagtaaa
    25201 ccaatttact ccaaaaatca gccgattcgg ctgtaatatc gctagttacc ccattagtcg
    25261 cacaggctgt catgattaac agagacagtc ctagcaaact agtcaacttt agtttctttt
    25321 tcactcccat ttccttcccg gtaaatcttt gataatttta atacatggag tagatttttc
    25381 tccatctctg cgtatcccaa ggtttcgact ccttttcgag caatgacaac aaagtcgaca
    25441 tcttctacca gacccccttt tgcattctgg ataatatgcc gaatccgtcg cttaatttga
    25501 tttctagtga cggcattccc cagttttttg ctaactgata gacctactcg aaaatggttt
    25561 ttctggtttt ctaattggta gaccacaaat ttgcgattag caaaacttgt cccctccttg
    25621 aaaatcgcct taaaatcttt ctctcttttt acacgaaagt ttttcttcaa aactcaactc
    25681 catctattaa attactacta ttataccata tttttcaaaa aagccaatca tagcaaggtt
    25741 ttggacaatt tcatcagaaa aagaagctgg aaaaataact ttcccaactc cttgtattga
    25801 atattttttt agtttcactt attttttcaa gcgttcaacg tcacgggcaa tgactaattc
    25861 ttcatctgtt ggaataacca agacacggat tttagctacc tctgttgaga tgtctcctgt
    25921 aacgccaaag acattctttt catcatcaac atcacaacca aaccacgaaa tccctgagat
    25981 tacatcacga cggaaattct ctgcattttc accgacacct gctgtgaaaa caatggcatc
    26041 tgctccattt agcactgcaa ggtactgacc gatatgtttt tggatacggt caacatacat
    26101 ttcataagcc aagctagcct cgtgattccc ttctgctaca gctgcttcta tatcgcgcat
    26161 atcgctagaa ttagcagaaa ctcccaaaag acctgattca cggttaagaa cacgactgat
    26221 atcttctggt gtgttaaaat cctctgtata ttgcattaaa taaggaatga tagctggatc
    26281 aatatcccct gtacgcgttc ccatcataat accaccaaga ggagtgaacc ccatagaagt
    26341 gtctacagat ttgccggctt tcacagctgt aattgagcct ccgttaccaa tatgacaggt
    26401 aattaacttc aagtcttcta atggacgtcc caagagtttt gcagcttctc ctgctacaaa
    26461 ctggtgactt gtaccatgag caccgtattt acgaaccttg ttttctgtgt aatattttgt
    26521 tggtagaggg tagcgataag ctttctttgg catacttgtg tggaaggaag tatcaaaaac
    26581 aactacactg gtaatgtctg gcaacaattc cttgaaggca cgaacacctg ctgcattggc
    26641 cgggttgtgt agaggagcca acaaactcaa ctcttcaact ttttctaaaa catctccctc
    26701 aacaactgtt gattctttga aatattctcc accagcaaca acacgatgtc caacacctgt
    26761 aatctcgtca taagccttga taatatcgaa acgaatcaag tcatccaata aaattttaac
    26821 ggcttgtgta tgattttcaa tatccaaaat ttgttgttca gaacggccgt caaattttac
    26881 agttgaaatt gaatctttca aaccgatacg ttcaatcaaa cctttcgcca atactttttc
    26941 ttctggcatt aagtataatt gccatttcaa acttgaactt cctgcattga ttgcaattgt
    27001 ttttgtcata acatgatacc cctttttaag cgttttcaac tattataaca aaatctattt
    27061 tatatttcag taccttgagt ccatttttga aaattttctt taaatttcat taaaacactt
    27121 gcatcttgca agctagcaag tggataaaca aaaggctcca ctgctatttc acttttcttc
    27181 tgtaggataa aaatagtctt agattgttta gcattagcaa agagattttc aggtaaacta
    27241 atcatagcaa ccagacttgc ctcctctttc aaccagactt tcaacaaatc actttgagga
    27301 ctggtcaaca aatcactcgg agctagaaaa atagcatatc catctgactt aaggtactta
    27361 aacccttgtt ccatgagcaa gtgatgagcg taagtatgtt cttggctaga agcaacttga
    27421 tggcgcgacg caacggcatc atcaggataa tagccaacag gcaagtcact gatgaccaca
    27481 tcgctttctt tgagcatttg tgggcgaacg gcatctcctt ggacaaagcc agcctgcaaa
    27541 ccaattacat ctgccatgct agctgccaga tcaatcagca aatcatccac ttccattccc
    27601 aagtaatcca cctttttatc aagcgaggtc aagaaagtag cgcctagaat tcccatccca
    27661 gaacccattt cgaggatagt aatttcctcc tctgtaaaca actcttccac aataaatacc
    27721 aaaagtaagg caatagcatc tggcgtaaac tggtgattgg cctgcaaggg ttctgtttgc
    27781 ccagccttca tcaagagaaa ctggtaggtc ttgagccatt cttctttgcg tagtgctaaa
    27841 cgcttaaggg cctgattgtt gtctttgacc tggtttagct cagtttcacc atccagatag
    27901 atgctatttt gctccaccaa ggcgtcataa aagttggtcg ccaaatcact ttggatgact
    27961 tggacattct ctagtaaata gatataagct tgttcaattt tttcaaaatc catattccta
    28021 tcttatcaaa tttcccttct tttttccatc cttatagaaa aatcactccc tgactaggcg
    28081 agtgattttt gggatactgt taaaaagaat tctgagtgat tcccttgaaa caggtcttca
    28141 gcgctataga gaatctgact atgcacagat gaaaaaccat gctcaattag cttgttttcc
    28201 agttcagcta aatcaaatcc atgatgatta gcttctgtct tggtaaaatc agcaatgatg
    28261 agtttcccat cttccttcaa atgttgatga aacagtgaga gatccgcatc caaatcaggc
    28321 atatgatgaa gaacccgact aacagcaagg caatcaaact ctttctccaa gggatttttc
    28381 ggtaaatctt gctccaaaaa ctggatattc ttgattgctt gctgctccgc tttcaaacga
    28441 gcttactcca acattttctc agaaatgtct acaagagtaa ctgacttagc ctgcttggct
    28501 aggggcaagg ctaatagacc cgtgccacca ccgaaatcta aaattacttt gtctgataaa
    28561 atatcaatct gtttctcgac tgcttgacat accaagtttg cgaggaagat atttttaggg
    28621 gagtcgaaag tttctgcttt gtggttaaaa tcatgtttca tatctttagt ttagcacaaa
    28681 gtatagtaaa ctgaaataag atataaacaa atgaattgga gcttaacatc catttccagc
    28741 aattttctag aaactacagt ggactattct ggattcaacg cattatagtt gaattgacta
    28801 ggaattctct ttcttttcag gcttctcttc tgattttttc ttctccactt tttcgcttga
    28861 atcggtcgct acctcttcct ttttatctct tttctcttct ttgattttga ctgaaggaaa
    28921 cagaaactca tattggctct tagacgtacg aacagtcgtc accaagcttg ttttcttgtt
    28981 ttgatagctt acctgaccta gattaaagac ctgttcccca ctttcttgct cggctttatc
    29041 cttggttcgt ttagccatgg caaaagcaac caatttttct ttatttaaag catagtcttg
    29101 atagtgggcg atttgtcggt tcaaataaaa ttgcaacaaa agactaaaga tggctgctat
    29161 ggtgactgcg tagaggagaa cacctgcctt aactttcttc tttttccaca cgatagatga
    29221 actccctttc taagcctttt tgaaactgga aacgaaaatg aaccagttga ttgtcctctg
    29281 taatctgagc tgatttgagg ccataaacca taggctgata cccccgtcca ctagcatcgg
    29341 ttttacgaaa atcgtctgac tttgacttac cgatggcgat gtccttgcca tcttgcttca
    29401 tgtataggcg attgctttct actttttcga actgcgaacg gtctaattct gcctcaagtt
    29461 ggtccacaaa caagagccac tccttttgct cgctttgttg ctggtagcga acttctgaaa
    29521 tgaggagctg actcatagct tgaaaaagga gtaatccccc actgatgaca atgagggcaa
    29581 gcagggattc taacaaggta aaagccttga ccttatggct ctttgattgc caacaactgt
    29641 tctgaaccat ggtagacctc caatcccttt tcactagaaa atacctgaat ctcaactccg
    29701 ttgatgctta cctgattttg ccccgtctgc aaggccatct tagctaccct caagacttct
    29761 tccttttgca agatttttgc ttcctcttgc ctattttttt gaatttgtcc caaaaggagg
    29821 gtcgcaatgc tggcaaagat agctagagcg actactgctt ccagtaaaat cactgcccta
    29881 attttttgtt tccttaatgc gtttaatttt tccatttcct agatataatt gatagcgaat
    29941 cgctccttta ctggtctgaa attcaacctt agccagggac gaattgcccc cagctcggtc
    30001 aaatgtaata ctttggcctg atggtgcctg aattccttta ggaactgtca acttttgacc
    30061 gccattgcta atcatctgcc catccaagtt cagactagtc ttttgttgac tagctacact
    30121 gcgtttttgg gtttcccgat agagttcttc aaactccata aagaaaatct gttcctctac
    30181 cgctgcaaaa gtggactgga cagagccgga caagcccaag gcaaggatac tcacaagtcc
    30241 caaaactaag agactttcca gcatggtaaa ggccttaatc atagacttta cgatttgctc
    30301 ctacattttt atcattgtat tctttataag ctttagcctg ttcttccgtg atgcgtccat
    30361 cttcttttaa cttgcttagg ctagcatctt cattcttttc caagctataa agttctgcct
    30421 ggctttccac caccttaaca acagctgctt ttcctttgtc attgactgct tctttttgct
    30481 tggtcagatt aggtacaaag agcaagaaaa gcacgctgat aatcagcaag accaccaaca
    30541 tttccaccaa tgtaaaagct ttaaccttag cttttttcaa gaatgtcatc atttttttca
    30601 ttttaaaaat ttacctccat attttgatac atgggcatga gcattgccgc ataaagtaaa
    30661 acgataatca gtgccacaaa gataaaaacc agtggctgca ccaaattcat ggtgcggttg
    30721 actcgggtaa aaaaggcttc ccaagttttt tcagcataga tttccaactc actacccagc
    30781 ttggacttaa cttccccata ctctatgata agactcaatt ccttcctaaa gaaaggatag
    30841 gttcctatcg tctgagaaaa ttcacggcca tttttcaggg tttgagccag atcttgaccg
    30901 atttctttaa agagctggga accttgttcc tgcatcattt gaaaaatctg cgtcagctcc
    30961 attccctgtg aaatcatatt cccccattca cgtgcataat aggctgtcaa gtaggtctgc
    31021 acaaagattc caataaaggg aaggcgtgct aagatagaaa agacactcat cttagaactt
    31081 cttttataaa aagttagtgc taaaagggca agcacggaaa caagccctac catgcctaga
    31141 aaaatttggg gcagattacc gataatttgg gtggcaatat tgctactatc cagttgtggg
    31201 agcaggtaat tccgtagccc cagcataatt aagagaagaa aacccagcaa aatcaaagga
    31261 taggtcgcta cttcaattaa ctttttcttg accttggcca gattgtctag atattcttct
    31321 atctttccca aactcaggtg gagattgcca tgaacttcag ctagggataa ctgagtgaca
    31381 atagcacttg aacatcccaa actttccatc atttctgaga atgattcccc ctgagacaag
    31441 cccacacgca tctgggtcac acactgcttg tccaacaaag cactcctatc taaaaaggag
    31501 atggtctcca ccagatgaaa accgctagaa aagagattgt taaatagggt gatgatattt
    31561 ttttgcttag ctgtagctaa ttttttccgt ctcagcctga agacttgtga tatgtccatc
    31621 tttaagaagc tggtcaattt gctcattcca cttgactgct tggtgttctt gataatctct
    31681 gtttgcaaag tcaacgattc ctcctccccc gattaatctc tggtagcaga ctccttgcaa
    31741 aacaactgcc aattcttctt cactcacacc caactccagc agacgctcat aaacacctcg
    31801 gatactcttg gcatgaatgg ttgaaaagac tgtcgcacct gtcaaactag ctctgaccac
    31861 tgcacgcgcc gtctcgctgt cacgaatttc tccgataatc aagagatctg gtcgatgacg
    31921 caaggaaagt ttgattagat tttcataggt taggccgatt gcttcgttca actgcaactg
    31981 aagcatgtcg tcctgcttga tttcgacagg atcttcgatg gacataactt gctgcccttt
    32041 aaagagtgac ttggacaatt catgcatcaa ggtcgtctta ccactcccaa ccggaccagc
    32101 aaaaagatag agtccccgtt gcctgtactg cttgcctaat tcttcaatat cctgaaacca
    32161 aaaatgcagg tcctgctcct catcgtgcaa caaacggata accaaactct catgcccccg
    32221 ataatcgcct acagtagata aacgtagaga cgctatcttc tggtcatagg cataatcaca
    32281 ggaacccagt tgactacgtc ttttttctcc cacattcata cccgccacaa acttaaagtg
    32341 actgataacg gctgcaaact tttcaaaatc atagctacca attttacagc gctcgtctcc
    32401 taccctcata tgaagctcat aggcgtctaa cttagggaca aaatagatat cctgcgtccc
    32461 ttttttccga gctgaacgaa tgatttcttg tgcaatttct tgaaccatac ttacctcctc
    32521 acctatacta ttcgcaaaga gttagaaaaa taaaaaaagc aactccaaaa aagttacttt
    32581 tctctatttt aatttcatac ggcaagaacg attcctttcc tgactagttt gtttttcata
    32641 gcctgagcgt agtttttcgt ctgggataac ctgctcatcc tgcaaaagag ccaaagaatg
    32701 gtattgttgt aaatactcat cacattcatc acaccagcgt tggtcttccg ggtcccaaaa
    32761 aatggtcatc aagtcgcttc tacttttata aagaggggat tcttgttcca atctaaacca
    32821 gcaagttttg tagtatttga gagcatcata atactggtca aattttctac ttgctacaat
    32881 atcttcttcc caaccttcta agaaccacca cggttcaaaa tctccgtaca tttctataac
    32941 acgatacata ttcattcatt cctttgtacc gtatattata accaattccg ccagacaagg
    33001 aaagaaatat gctcatttct taattttttg ataaaaaatc cagccatctg atggatgact
    33061 gaatttctat ttacttatgt acaaaaatat ttttactact tagacttctg agatatcgtt
    33121 ttcgataatg accttaatgg catggtggtc tgctgcctta ctgaagactt cgtaggcttt
    33181 ttcaatttca ctgagtttga aatagtgagt taccaatttt tctggttcaa tcttatgact
    33241 ttcaagtgct ttcaacaatt gtggagtcgt atttgtagat accaaaccag ttgttacatt
    33301 gatgttgcga atccaaagtt tatctaaatc gaattcaact ggtttaccat gcacaccaca
    33361 gttggcaacc gttccgtcta caccgataat cttttgacag aaatcaaatg ttgcaggaat
    33421 accaacagct tcgatagcga catcaacacc acgaccatct gtcaaatcat aaatttcttt
    33481 aatggctttt tcagggtctg aagaattaac cttatgagtc gcaccgaatg atagggcagt
    33541 ttccaagcgg ttatcgtcta ggtctaccat aatcaattta gctggtgaat agaattgggc
    33601 tgttaaaaga gcagccaatc caactggacc tgaaccaata atggctacgc tgcaaccagg
    33661 ttctactttc ccttttaaga caccaatttc atatccagta ggcagaatgt ctgacagcat
    33721 aaccaaagct tcgtctgaca agtcttctgg agtatggtaa agagtattat ctgcatgagg
    33781 gacacgtaga tattcagcct gcataccatc aatcaagtga ccgaaaatcc agccccttcg
    33841 tcttcacagt gggcataaat tcctttttta cagtagtagc atttaccaca ggcacagacg
    33901 caagaaatca agaccttgtc accttttttg aagttggaaa ctccttcccc aacttcttca
    33961 acaatcccaa tcccttcgtg gccaagaatg gtaccacttt ggcaagtagg aacatcccct
    34021 ttgataatat ggaggtctgt tccacaaaga gtggttttta caatacgcac aatagcgtct
    34081 gttggcttgc gaataactgg tttgtctaca tcaacaaaag aagcaagtcc tggtttaaca
    34141 taagtatagg cttttataaa gcactcctcc gtttttttat ttgtactatt tatagttcaa
    34201 ttgtaagcct ttttctttgt ttcttcaagc tttttttgtg atttttttaa ctttttattt
    34261 accagtaaag taccctatat aaaaaagcag aagctagtct ctaacttctg ctttctctct
    34321 tatgcttgat aacgttttac gccatctagg taggttgcta ccaattccaa atctttatct
    34381 aatacgatga agtcagcgtc gtagccttca cggatttggc cacagacgtc atcgatgtga
    34441 acggatttag ctgggttgaa gctggccatc atgactgctt catgcggatt cgcaattccc
    34501 cattcgacca cattcttcaa accatctttg agtttgagga tagaacctgc caagttacct
    34561 gtcgatttga ggcgtgcagt tccatttgca acgacaactg ggaattctcc caacatataa
    34621 tctccgtctt ccaatccccc agctgtcata cagtctgtga taagagcgat gttttctgtt
    34681 cctttttgtt tgataagaat ttcgcaagcc tttggatcta cgtggtgacc atcacagatc
    34741 aactctgcat aggtatgtgg caattggtac atggctccaa ccatacccaa ttcacggtga
    34801 gtcaacccac gcattccatt gtaggcatgc acccaaacac tcgctccagc atcgactgct
    34861 tttttggctt catcaaaagt cgcatttgaa tgtccaagag caaccgtcac accttcgccc
    34921 gtaactgtac gaacaaagtc ttccacccca tcacgttctg gtgcaagggc aattttatta
    34981 agcaagccat ttgccgcttt ttgccaagaa tgaaactcct caacacccgg gtctctcata
    35041 taagttggat tttgtgcccc cttaaaagtt tctgtgaaat atggaccttc ataataaatc
    35101 ccacgaatct tagcacctgt tgcttcttta taatggtttc caagattttc agtgactgca
    35161 agcaattgct cataagtggc tgttaaagtt gtgggtaaga aactggtaac accggtacta
    35221 agaagtcctt cactcatagt atgcaatgta ccttcaatgt tgttgtccat cacatctaca
    35281 cctgcatatc catgaatatg agtatccaca agacctgggg caatgctata acctgtatag
    35341 tcaatcacct cagccccttc aggaatctgc tctacatgtt tcccaaactt gccgtccaca
    35401 agttccaagt aaccacctcg acgaactccg tgtgggtaga aaaactgatc cgctttaata
    35461 tagttaggca taatgttaac ctccttaaaa gattgattct acaatttatt atgtcaatta
    35521 cattataaac ctttcttttt tatttgtaaa tggtatagac ctattttttg gagatatttt
    35581 aaaagagctg gatttctcca actcttctct tttttaatac aagttatttt gatttaaccg
    35641 gcttgtcttg agctgtctgc aaagctgtgg caatcgtatc tgcatacaat tttgctcctg
    35701 cttcgatagt gctactctca ctcccgaaat gaacctggtc tgttcctgcc caaatttctg
    35761 gatgctcttt cgcaacttga ttccaatctg ctatcgtaat gtaaggtgtc ttctctgcca
    35821 attctctcat ataggcagca gccttctcaa cgatggcata ggtctctttt gtcttatctc
    35881 cctcataagg agtcaccaaa atcatacggt gtcccttagg aagatttttc acgatactgt
    35941 cccagtcatc cttgtaattc tcaggattat ttaccccagt cgcaatgacc accgtcttag
    36001 gtaaaaattt attctggcta ttatttagca tgatttcatt tgcggtcttg gttgttacgc
    36061 tgacctgcgc gttaatctgt gctccaggaa gagctgtctg tagtgctgta tttgccctta
    36121 aagccactga gtcaccaatt aacatagtgc catcagcaat tcccaaactg tttgcatctg
    36181 cccgttctgc catcaccttg gtctggccaa tatttgttgc agcttgcttc aagccattaa
    36241 cagtcaagtc tgtctcaaac gctcccactt gtggtgccaa caaggtcacc atgcagacaa
    36301 tgaaggtcaa gattcctgta cctgctgcaa gaattgcgtg aatataaggc aggggacgaa
    36361 gagtttgtaa aataggtgtg ttcttgcctg caatccaagg ttccaataca tagaatgaca
    36421 gactggcaaa gccataagaa caaatcagag tcagtaatac agcaagaaga tttgatgtca
    36481 actgtgagaa aatgatatag gaaggccaat ggaaaagata aaccgcatag ctagtatccg
    36541 ctaaaaagct gataatcttc ggctcctgta tatgatgtgt cttttcatgt aagacacgcg
    36601 ccgccagaat catggcaaga gctgcaagac tggcaagcaa gaagccgata agataggcaa
    36661 aaagataagt gaatttgaca aagaaagtca aaagaactag gaaaccaaag cctcctccaa
    36721 aaactaccaa agtctttcgt aaatcccaga ttttatccaa ctgcttgacg agggaagtcg
    36781 tctgacgaac gcctacaata gttgctaaca tacttcccaa aaagaatgga tagacatgag
    36841 ttaaactgga gaaataaaca gaggaataag aggtcactag aaaactacca ataaacatgg
    36901 agaagaaact gatcaagaag gcagcagcag ataagagaaa gaccatcccc ttcaactgac
    36961 catttgattt agcttgtttg gataagaacc aaactgccaa tccccaaaga atatagtagt
    37021 gaacctcaac tgccaaactc caattatgaa caaacaaatg aggaatgaac tgagattcat
    37081 aactcccacc tgttaggagt tcatagaagt tggtcataaa gcctaagacg cccgcaatct
    37141 ggccaccaat tccagcaaca tagtcttggc gaaccaagaa agtaaaaggc atggtcacca
    37201 agaccatcaa aaccacaggt ggcacaatcc gataaaagcg tcttctaaaa aatcctatca
    37261 aatcaatctc attgttctta gaaaattctt caatgagtag agctgtaatc aggaaacctg
    37321 aaaatgtgaa aaagacatct accccgaaaa atcctccagg aaagatcgtc tgaaagaagt
    37381 gatacaagag taccaaaagt aaacctataa tcctaatcaa ggaaaaccat ttaatgcgca
    37441 tacgagttta ttcttccttt cattgtacac tttattctat caaaaaaaga agaaaaatcc
    37501 taagagaaaa cttaggattt ttttatatca attccatttt agaaattacg tcctgactta
    37561 ttatagccat atttttccac aaaatactca cggaattcca agagattgtc atccatgatg
    37621 gcttgtcgca cttgcttcat caggttaagc aagaagtaaa gattgtggta gctagtcaag
    37681 cggataccaa aggtttcatc agccttgagc aggtgacgaa ggtaagcgcg tgtatagtta
    37741 ttacatgtgt agcagtcaca ctcaggatcc agtggcgtaa agtcctcagc aaactgggca
    37801 tttttcacaa ccaaacgtcc ttgactggtc atacaagtcc cgttacgagc aattcgagtc
    37861 ggtaagacac agtcaaacat atccacccca cgaatgaccc catcgatcaa gctatctggc
    37921 gctcccacac ccatcagata acgaggttta ttttcaggta gcagttgagt tgtaaagtcc
    37981 aagaccgcat tcatctcttc atgggtttct cccactgcca aaccaccgat agagtagcct
    38041 gagaaatcca tgctgacaag atcatgagct gattggcggc gaaggtcttc aaatcctgca
    38101 ccttgcacaa ttccaaacaa accttggtca tgtggacgac ggtgagcctt caaaccacgc
    38161 tcagcccaac ggctggtacg ctcgatcgat ttcttaacgt agtcataagg ttgataaaac
    38221 tgaggacatt catcaaagga catcatgatg tctgaaccca gattattctg aatagagatg
    38281 gctttttctg gggataggaa catcttagaa ccatttagat gatttttaaa ggttactcct
    38341 tcttctgtga tattacggct atctgctaaa gaataaacct gaaaaccacc actatctgtc
    38401 aagataggct ggtcccaatt catgaacttg tggagaccac cagcgcgtgc aatgagttca
    38461 tctccagggc gaagccagag atgataggtg tttgatagga taattcccga acccatctcc
    38521 ttcaattctt caggtgactg agttttgaca gtggcttgtg tcccaactgg cataaacata
    38581 ggtgtcggaa aggtaccgtg gggagtgatg atttctccta gacgagctcc tgtgtgtttt
    38641 tctttcttaa tcaaacgata tttgattggt gaatctgaca ttttttacct ccgaagctgg
    38701 gaaagacagt cccagttcat acagtgtgcc caaggacaca ctgtatgatt ttatcaaaaa
    38761 aagtaggaac tgtcacgaac tatgtataag aactatggta taataagaga atgaactatc
    38821 caaaaattga tttaaaaaca attcgtcagg agtcaaaaca ttttcaggct gacacccccc
    38881 gtctctttct cctctatatc cttcccagta tgctggtcat cttatctagt tttcttaatc
    38941 ccttatctcg gatccacggg actgttttag aacagccatt tttcagcata cttggccaaa
    39001 tacttcaagc ctacctcttt cctctactag tctcctttat cgggactatt cttttgacca
    39061 gttccgtcta tgcaacactg acactcatga aagattctaa aacggagcca tctgtaaaaa
    39121 acagcctagc tctctttgat gaggagcgct tttctcaaac ctttttgacc ctacttctca
    39181 aacgtttcta tctcttttta tggagtatcc ctaatttact tgggatttac ctcctctttt
    39241 atagtagctt tttagccaaa aaattcgtca ccctacatcc tgagtttcca aatctagatc
    39301 tctcatcagt tgaaaccgag cgtttcctca tggtctttgg actctacttt cttgcaagtc
    39361 tcatcttgat cattgtaggg aatatcctct atattccaca gtattatgcc tattcacagg
    39421 tggaatttct tctctgttat agtctagacc taggacaggt cccaccaaga cgaatcctaa
    39481 aaactagccg ttcctttatg aagggctaca agttccagca ctttgtccta gatttacagc
    39541 ttcttccttg gtacttcctc aattggatta cctttggcat tgctagtttt tcactcctac
    39601 cttatatcca atgcactaaa attatgtttt accgagcagt attggctcga aaacgtccaa
    39661 aagcttgaag gtttttcccc tcaagctttt ttctatcaat gagtttctcc gcctaccaac
    39721 ttgagttcct gatctccatg ttctatcata gcgccgattg ctgcttctat ccctcgccga
    39781 atatccacta aactcatagc tggaatagtc ggtctgttca ccacctgttc catcatataa
    39841 ggaatatgca taaaacctgc cttaacatat ggaaatttct tttctaccaa atagagagcc
    39901 tgatacatca aatggctgca gacaaaagtc cctgccgtat tggaaacaga ggccggcaat
    39961 ccttcttttt tatagcttga accatcgctt taatcggcaa actactaaag taggccgaag
    40021 caccatctgg gcgaatggga cggtcaatcg gttgattatc ttcgttatca gaaatgcgtg
    40081 catcgtcttg attaatggcc actcgttcag gtgtcaaact agttcttcca ccagcttgcc
    40141 caatacaaag gacaaagtca ggttgataac gattcatctc ttcttccaat acttgagcag
    40201 atttgtgaag aactgtcggc acctctagcc aacggacctc agcaccatgg atttcagctg
    40261 gtaaaccttt aatggcctcc aaagctggat tgcccttttc ccctccaaag ggctcaaaac
    40321 ctgtcactaa tactttcatt tctaactcct caaaaccaat tcaatgagac ttttttctta
    40381 aaaacaagta taacatattt cccttattct ggattaaaaa ggattagcga gattagaatc
    40441 gaccttcaag tgtatttaaa gagtaaaata ctaatcaagg ccaaaatagc tgatccacct
    40501 tgtttcaaaa taattttttt atccgctgtt aaagagccgt aagtcgcagc accaatcaca
    40561 aataagacaa aaatagtcac aatttctaaa ttctgtgaga aataaatgcc atacaagaga
    40621 aagactccta gcagatcctt ataaattcct tgatttttga acaatgaact tactgacgga
    40681 tgagccaatt cttccttttc catattaaat acacgactag tcgcatctga ttgcgtggca
    40741 atactttcca aataaaaaat gtaaaaatgc tccaaagcaa cgatcgttgt taaaataatt
    40801 gacatctatt tctccttaaa tttctatatt ttcaataccc aaaaccaatt tatttaataa
    40861 acggctgagt tctgttctct caaactctgt taagatactt tccatctctt ccttaacctt
    40921 gatatgttgc agagggggat tcaccactaa ctgctccttg gcatacttcg cagcctctac
    40981 caacacttcc cgctgatttt caggattacg atgacgctcc accaaacctt ccgtttccaa
    41041 aatcttgaaa tgccgtgtca aagcagcctg atcaattttc aaacgctcct gaaccgccat
    41101 ttggttacaa agagaatgct ccagcaaaaa cagtaaaatc tgataccgtg tcaaactaat
    41161 cccaagcctt tttcaaacaa ttgcgtactc gcttgctcag acaagcggag ttgatacagt
    41221 aaatcttgaa tctctatcat ttcttcctcc tatccattga cttatcaata gttgaccaat
    41281 caattgtgat ataaagtaaa atagattgca agaatgttgc ttggattatt acaagataat
    41341 aactttccat tttccattca aattgatact caatgaaaat caaagagtaa actagaaagc
    41401 tagtcgcagg ttgctcaaaa cacagctttg aggtttcaga taaaactgac gtggtttgaa
    41461 gagattttcg aagagtatga caaagaaaaa acgaacgaga atcgctttcc atcacgaaag
    41521 ctagatctca ttcgtcaaaa tgatgttatc aagtcgggtt tatccattca ttgaaacgtg
    41581 aacgtgatca tagtgatttt ctgtcacact accacggtct ggcattgggt tccaagtgtt
    41641 agctggccca tatttgctat cgaatggagc atagaaacgt tgtttccaga tgatgtaact
    41701 aatgccacgg ctggccatat tttgaatagc atattccgca atcttatccc ctaattctga
    41761 atgttctggt accataaaat cgatagccaa accttttccg tgatctccac tgtctcctgg
    41821 acgataacca ctaaaggatg taatgccaaa caagttagca atttcttctt taaaggcagc
    41881 tgtttgtggt tgaagacctg cattttcaga ttttgctact gcaagtccag cataatcggg
    41941 cgcagctgga gcctcgtaag ttgttgaaat tattttcgtc tcttctggtt gataagtaga
    42001 aactgctgct gtagctccat ttgatgatgc tacttctttt gcttctgaac ttgttgtagt
    42061 tacttccact gctgatgcag cttgagggct tgcttgtgtt tcctgcttct cagctggagt
    42121 cgtttcctga ggagttgctt cttcaactgg gcgagttgtt tcggtcgttt gctcctctgg
    42181 gacagaagtg cccgtagatg gtgccacttc ttcagaagca atcactgtct ttgtaacttc
    42241 tgaacttgat gctacttctt ttggagcttc tgcaattggt tgagaaaggt ctgcaacctg
    42301 aacagtttga tcatcaacgg tcacttgatt agtggtcaaa tctgctgtcg cagttgtcac
    42361 ttcttcacta gagtctgctt gaggtgtttg gatttcaact tctgttactt cttctgcttc
    42421 attgacagtc gttgtcaaaa cagtttctgg gaaaatcaag tccatattag tgattttatt
    42481 cagattcgca agcactgtga catctacacc caaggcttct gcaatggtgc tcaaagtatc
    42541 accatactgt acggtataac ttgttttgtt gtccgtttta gtcaaatcgt tttggatttg
    42601 ctcaacacta cgtgcagtcc aaagaacttc ttctgcttga gttgccaata ctggggcaaa
    42661 tgacaaggct actgttgacg ctaataacat tcttttcttc attctttcaa attcctttca
    42721 aatgagtacc tgtctatcat aacacaaaaa atgtagaaaa aaagccctct cgggcctatt
    42781 taacagaact gtctattcct tgtaacaaac taggttactt gaaatagttt gttaggtctc
    42841 tgtcacaaaa ctgacacaat ctttttatca cttagtctca aaaatacggg aaatatctgc
    42901 taacgcttga atcctgtgat tcccttcata agtagactct aaaaagttga tgctttgaat
    42961 cccactattc tgggcaaatt ccacatccag agtccgatcc cctatataat aagtattatc
    43021 agaattcaac tgatacttat ctagcagata ggtagccgct tctggacttg gcttccgcac
    43081 aaagccactc tgactggtta aaatctctgt aaaataggat tccaccccca agtccttgag
    43141 aatggtaaaa gcgttgttcc ccttatgagt atatataaac tgctgaattc ctgattcgtc
    43201 tgcccaagct agcacctcac gcgcacctgg catcaaaact acctgagcat tcttctcagc
    43261 cagactctgg gcacgcacct gatttagcac ctcaacatcc agatttctat cttctgccac
    43321 ccgcacaagc aaatcttgca ccgaatactt gaagataaac tctctcacct tctccttatc
    43381 ataaggaata gaaaactgag caaaagtctc ctcaatccct gataaaatcg cttcgtaaga
    43441 gtccaataaa gtcccgtcta aatcccaaat aaaagctgtt ttttgcattt cctatccttt
    43501 caagctcata tagcgctggt aacgatagcg tagaaataac cagcgaaaac cattatccaa
    43561 gagagaccct gcccaaatac caggcaagcc ccaaccaagc acaatcccca tcagatatcc
    43621 tgtcccaatg cggatacacc acatgcctat acttgtcgca taaaaaggga ggcgtgcatt
    43681 tcctaatccc tgccagactg ccgtatagat gactgttcct gtcgtcatag gggtcccaag
    43741 tagtgaaaac agtgtcacta gaacactagc ctccaccgct agagagtcag tcgtatagag
    43801 atgagttaat ggtacaccca agacatatat actaaaggac aggggcaaca tgaggaacag
    43861 agaaagccaa aaggtttgtt tactcaaact agcaactctt ttccaatcat cctctccaac
    43921 tgctcgggcc aacagcatga ccgttgccgt agcgacgcca aaggcaggca tatagttaaa
    43981 ctgggtcaag acttctccga ttgcattccc agcaactgcc tccgtcccaa aagaaacgac
    44041 caaggcaatg atcactacat ctccagccct catcataagt cgctctccag ctgctggtaa
    44101 agccaaggtc aacagttcct tatctaaacc aaaagttggc ttcccataag gcagttttaa
    44161 ttgtgaccac aaaatcacaa gaccaaccaa acgagacaca attgtccccc aagcaacacc
    44221 agctatcccc atatccagaa caaaaatagc tagacttgaa aaaagaatat tcaaggcatt
    44281 ggataaaaaa ctaacataga gaggcagacg tggattatgc gttgcacgaa tcaaggctcc
    44341 cagactagtc attaaaccta agagaacaat cgatccgcct accaaagata gatacagtcc
    44401 accactctca gctacatccc tctccgtccc caaaagtcct atcatctctt tcccagcgaa
    44461 gatggacaaa aatcctaaaa ggaaacttaa tagtaaggta atcttcaacg cctcagtcac
    44521 atgataggcc aacttcgact ggtctttctg ccctatgctt tttgaaataa cactggaaat
    44581 agcagctccc agagcgatga aaatcgcctg ataaatggtg ataatattac cagctaccga
    44641 aacccctgaa atagctatca atcctaaatg agcaaccaaa taactgtcca ccattcccat
    44701 tagcatctgc aaaaagtttt cacccatagc tggcaatgca atattaagaa tgtctttatt
    44761 tttcttaaac aatctctcct cctgatgaaa agaaactcag ttggtttccc aaccgagttt
    44821 actccctcta tcttaaagtc ctaaataagc ctcaaccgct acttgcatgt cagcagctgc
    44881 cactgttgtc ttgtgacaaa caggagctgt ctcaagccca tcaactgctg gtggcactgc
    44941 aacgcctgag atttcatgta attgagccaa agcttcaaag tctgttaaac ctgcttttcc
    45001 agttacagct tctactgcaa ctactgggaa cttgtaggga ctagctgttg aagcaatcac
    45061 tgtcttagtc gcatcatcag taaccgcttg gtattttcta taaactgctg aggcaaccgc
    45121 cgtatgtgga tcctcaatat aagaatctaa ctcataaaca cgcttgattt ctgccgctgt
    45181 ttcttcctca gtcgcatatt cagctacaaa gagctccaga atctctgcat caaaatcagt
    45241 cagttcatat tgtccttgtg tattcaaggc attcatgagt tcagccgtct taaccgcatc
    45301 attccccaaa agatggaaaa tcaaacgctc caagtttgaa gataccaaga tatccataga
    45361 tgggctggtt gttaccttaa actcacgttt cttgtcgtaa acacgtgtct tgaagaagtc
    45421 tgtcaaaaca ttgttgtcat ttgaagcaca gatcaattta ccaactggga gaccgatttg
    45481 tttggcataa aaggcagcca agatatttcc aaagtttcct gttggtactg tgaagttaat
    45541 cttatcacca gccacgatct caccagtctt gaccaactga gcataggcat aaacataata
    45601 aacaatctgt ggcaccaaac gaccgatatt catagagtta gcagatgaaa attgcaactt
    45661 gttggccgct aatctttcac gaagagccac gtcgttaaac atgtgcttca catttgtttg
    45721 cgcatcgtca aagttaccat caatagcaat aacatgagta ttgtcgccag tttgagtggt
    45781 catttgtaac tcttgaatct tgctgacacc atcctttgga taaaagacga taatctcagt
    45841 accaggcaca tccgcaaacc ccgccatagc agctttcccc gtgtcaccag atgtcgctgt
    45901 caagataaca atcttgttct ccaaaccatg tttcttagca gcagtcgtca taaagtatgg
    45961 caaaatagac aaggccatat ccttaaaggc aatcgttgaa ccatggaaaa gttccaaatt
    46021 gtattgccca tctaatttca ctaatggtgc aatagctgga gtatcaaatt tactatcgta
    46081 ggcattgttg atacagtagt ccaactcctc agctgtaaag tcatctaaaa atgctgacaa
    46141 aactagctta gcaacttcct ggtaagaagc atctttcaat ttgtcaaagt ccaaatctac
    46201 ctttggataa gtaaccggtg taaacaaacc gccgtccgtc gccaaacctt gcaaaattgc
    46261 ttggctggca gttactgtat tgttggcatc acgcgttgat tgataaacta atgtcattac
    46321 tctctatcct ttatctatag tctcgtccat tatatcatga tttttcagaa aattctccct
    46381 ttataagaga aattataggc tcaattcttc tctcaaaggc tgtaaatagg tcatttcttc
    46441 cttatttctc accactagtc cctcctcagc tagtaggagt aagtctttgg aaaattcaat
    46501 aatcgtagtt tcttcctcat ctgtaagatt tttcttagaa aattgtctcc ttaaagactt
    46561 gtaatcataa ccaaatactt taaagaaagg tgctgtttct aagtaagctt ctaacttgtc
    46621 taaattaacc aataatccca agtgaaaagc tgcagaagca aaagttctat caagtggctg
    46681 tgtacacaca ctacgaaact caactgttcc tcgagtcgtt aagtcttggt actggtaact
    46741 acgatgagtt tcaaaatcct tctcttgggg gtaaataata acctcatccc cattcagaga
    46801 aaatgcttgg atttcaggcg tagccaaata gtccccagcc tgaataggat aaaaataata
    46861 ggtctgccca tcacgttccg cagtaaaaat cgcagaatga tttagatagt caaaaaaatc
    46921 agcttcatca ttaaggagtc tagcattgac cccaacattc tctggataga taccatgcat
    46981 agattcttcc cagaaaatat cccttgaaat tttcgtatcc caatccgcac ccgaaaattc
    47041 agagtttgca aataaataag ccttagccgc ttcaatttga gtaaaagcat taatcacccg
    47101 caagtagttg gtttttgaaa tatccagctg aacctggctc ccacagataa aagtaccata
    47161 ttcagggaaa tgatgtaaat ctgatttaat aatatttcta ctcaaattca aataatccat
    47221 caacatctga tagcgtggat aagccactgg acaattctca tttttatccc agttgggatg
    47281 gataccacag ccaacaatag catgatttga ttcagctaac tttctctgaa ttacattcat
    47341 ataattattg aaacgatttt cgacctcttg aatcgtttca gccttaccaa atgcaaactc
    47401 aatcgttgta taggaaactt caaataaaat agcatcctga cttatcggat ctactaactg
    47461 gatcagattg ccaaaatcat ctacctttgc tacggtgaga tccaaagtag aaactaaata
    47521 atgaaataga tcctttataa cttcaacatc tgtagcatcc ccttctaaac ttgcaacagg
    47581 atactccaac tcaattccga caaacaattc aggattttct ttaatatttt tcaaataccg
    47641 atgttttaat aaatcgatag aacaagacat actaccctac actttcttaa tctaaataaa
    47701 atttgaataa ctataattat accaaaaata atataaaaaa ggaacgaaga ataacaacgt
    47761 tcctaacact atactatacc ggcggccggg gtcgaaccgg cacgtccttg cggacactgg
    47821 attttgagtt tgattctatg atattcttaa cttcataaat ctagtaaaat caaattttca
    47881 ataaattatt tctatcgcaa aaacgataga ttttttcttt ttagtaacat tttagtattt
    47941 gatagcttgc tcactatatt taaatactgt tcttttctct tcaaaaaata ccttacactt
    48001 tttcacttct tcatcatagg cagtaaagag ttcttctatt tcccaatcgt tataactata
    48061 atttgattta ttgctaagat ttgtaagcag gttcattaat gaaaaaattt tctccactct
    48121 tgcagttgat agtttcttaa agtatacttc cttgtcatta cttgtatcag tagaggaata
    48181 attgaactct tgttttagat taactgtttt tatagtaata ggactagtga aaaattcctt
    48241 tatttcttcg cccttttgtt ctaacgcccc aaaaagttct ttaatatcag cttctgaaaa
    48301 agaatacttt gatttatcac tttgatttct cagtatattt aagattgaaa aaaccttagt
    48361 catccttgct tctgacaatc ttctaaattt ttcatttcta gtttccatag tttctccaat
    48421 aagtaaattt tatttcttta tcctatatat tatcatatag cgagattttt ttcaaatatt
    48481 gcattttatg attttgtgta gtataatatc ctatatagag ggatatcctc taaatataat
    48541 acccaaaaag gaggggttct tatgtttaaa gaacttatcg aatttgttaa ttcctcaaca
    48601 gagggacagt ttaaagcctt tcaagtcaag gctaatgcaa taacaggaga tgttatcatc
    48661 tctcaaaatg taacacctat cactgacgcc ttaaaaaatc gtctaggatt aaaaactgtg
    48721 caaacctctt tagcaaggaa gttagcttac gcttctactc gtcgccacta taaagatggt
    48781 acaacaatga tggaagacat cttagctggc aagacacgtc gccatgcaaa cagctacatc
    48841 tagatgactg ggggagctaa cttctcccct ttatcttttg attgaaatag aaaggagtga
    48901 catcatgaag agtctctata aatatctttt ttatttgttc tttattggat ttgctggcac
    48961 actctgttat gtgttgcttt taacaaatgc cttttcacct atctttgaag ctgctacaat
    49021 attgatggag attatagttg ttattttttt aataatctgt atagacctga ttgcttcccc
    49081 tactggttct gctgaggaga atataaaaaa tgagaatgtt aaatcaaaca atccgtgtga
    49141 agagtaaata cccttacttg attcgtcctc gaaatattac cattactaga ctatctatcc
    49201 aagtttttct ttttttacta ttggtatctt catggcttgc tgcaatccca tttattgcac
    49261 gtctagtctt ttccatgttt tttataagtc ttcttttttt agtagagagg ttctttcatt
    49321 ctgatgttat agaaaaattg agaaacaagc tcaatatcag agaagctttg ttttacatgt
    49381 taattagttt aactttatat gatgatatag ataatgaagt agtagataca gccgttttat
    49441 attttgacgt ttctgagaat gacaaggtta ttatctgtgt cccattattt gggaaccgtt
    49501 atctgaaaac cttgaaaaat ttagaggaat atctctgtcc cacattgggg ttgtccttaa
    49561 tttttaaaaa agaagagatt gataaaatag tatatgtgtt agggaagata gaagaaattg
    49621 aacaatacgt tttcaatact aatacattaa ctagggagtt ttttaaggat attcctagtc
    49681 caataatcaa gctatcaaat acccaacaat tctctctgaa atcgaatact aatatcggta
    49741 tttatggacg cactggaaca ggtaaaacaa tagctctcca atggtattta tttaatgctc
    49801 ttgctaaagg gtgcggaact gttgacggta cttacttagg cattgtagac ggaaaagggg
    49861 cagacttata tgcattaggg aagctacttg aagaagaaat aggaaatcaa gtcactgtgg
    49921 gtacttctcc aacctcttta gcgaaattgt caagggaatt tgtagaaatt atgaacgaac
    49981 gttttgaggt tatcaagcag aacagttccc taaatgctga tgcttatgat ttaggaatga
    50041 tacctaattt tctatttgta gacgaattgg catcaatacg cgatagttgt tgtggctcta
    50101 gcaaacaggc gaaagaactt tggaatgaaa ttctacaaaa tttaggattg attgcccgta
    50161 aaggaaggca ggctggttgt cacttagtat tatccacaca agaccctaat gctgagaata
    50221 ttccagtaga attgagaaat caaatatcgg cagttttata ccttggaggt ccaggtgctg
    50281 atagattgaa gatggctttt agcatgtgcg aattagaaaa cgttcctact gtatccgata
    50341 gaaaaggaga ggctctcttt tatgctgacg gtttaaattc agttgagcct gtattgacaa
    50401 tcgttccatt cgttgacgta aaaaccaaac aagaattttt acagatagtt aaaaatatac
    50461 tgccaaacta ctaatgacgg tatttttctc tgttggaata ggaattcttt tcaatagaga
    50521 aaaagagcca accgactgca ttgcaggagg taagaaagaa aggaatttat catgaaatta
    50581 aatgattttt tgaaacccga actactaggc aatcgcttct ttgccgtgaa agggtataca
    50641 gaagtattag acagagagac taataaaccc gtagctttac gacttaatgt gtcaattcaa
    50701 gatgagaatt ctgatttctt tatggagatg atacaagtca aaataaatac attatcgcct
    50761 actgcttctg ttcaagagat ggcgaacaac aaaacttgtc ctgttagtct taaagattta
    50821 aacgtagggc aattcaatgg aaatttgtgg ttcgcttgtt ctgatgtttt acctgtaaca
    50881 aaatagctaa gattaaataa tatataaagg agttttacaa tgcaaacttt taactacgat
    50941 gattttaaga atgaaaaggg gattgtttca ttttctgaag cagaacaaat ctattctagt
    51001 ctccttaatt cttccaatca acttgataaa gaatttcaag aagaatggac aacatttgta
    51061 cttctatgcg tagagtatgc ctctgcacgt ggtaaatggc tcacactctc aagagaagag
    51121 aaacttgcca atgatgaatc tagaactgtt actcacaata aagttattta tcaactaaag
    51181 attttaaaag gtttagcaag tgaacagggc aatgatgttg cttggtttga acaatttaac
    51241 gatgacagaa aacgtattgg cgactttgct tgctatgtag cttatatcta tgccttaaat
    51301 gctcgataga caattagagg atattatagc tatatattac tctatgtctg atattcatgg
    51361 aaattattaa ataacatctt aagaataatt aattctattt atctatcacc gaaacaatgt
    51421 gctataactt aattcgattc ttagactaat atcaaaaata aagaggggaa tatatatgaa
    51481 gacgttatta attggtgatt tacacttaaa atctcaactg attttaccca ttgttgacaa
    51541 aattatccaa acacataata ttaagagaat catttttctt ggtgattacg ttgatttaca
    51601 tggtcaaact aacaatatcc aactttatgc caaagacctc acttttttat actcttggaa
    51661 aatagataaa gagcaaaacg gaatagatgt aattaatctt ataggtaatc atgatgctta
    51721 ttatttactg ggagaacaag ctcctttctc aattcaaaac ctagaggtct ttttcgcagt
    51781 taaagaattg ttgcaggatt tgaaattaca agtagcttat caactagatg attatttagt
    51841 cagtcacgct ggtttcaatc tgatatttga cccaaaagaa tggcatttta acctctatac
    51901 caaagagcat gaagaagaat tagatattct agcttataca ataggaccaa tgcgtggtgg
    51961 gaaagctctt ggggggtctc ctttatgggc acattttaga gaattagaac tgcttcccaa
    52021 ccaagacttt cctaaacaaa ttgttgggca tacccctaaa gaatctattg atatttctaa
    52081 aaatgttatt ggtatagata ctttttcatt atatattgac aaagataata aatatcaatt
    52141 tattggtaat ggagatttac tcgtttatga ccaaggacat tttgaggtca tttcaacaga
    52201 ctgggcaaca gacaaaatat taaaacaatt accacgacta taaatttaat agctacttct
    52261 catcatgtac ctaagcaaaa ctgccgacta agtcggcaag ctggaagtgt gtttagcgga
    52321 gcggtgctta gtcacatgat agaagtaggg aggagcaatg ctcctcttag tttatttatt
    52381 atatagacaa tcttttggcg aaagccaacc taaaaggaac tattttttat gacctcatat
    52441 aataaaaaaa tagtccgcac ttcttcctat attgaaattt gggaatatga aaagccaata
    52501 ttttcaaaag gaaaatccat tttagatact gatattaaaa gcaaagaaaa attacaacgt
    52561 agaacatttg atgaacttac acctgaagaa caagaacaac gtctggagcg tatgaaaaaa
    52621 actcgcttag aagcaaagtg gaacttactc cgattagtcg attgtaatta tgatgacaat
    52681 acttcatttc taaccctgac cactaaagaa aatattagcg acagaaacca cttcaaagac
    52741 ttactaaaaa cttttataaa acgctttaac taccacatct ttaataccaa gaaaagtaaa
    52801 ttaaaatatt taacagtatt agaaaagcaa aaacgtggag catggcatgc tcatattctg
    52861 cttttcagcg ttccttatgt accacaccgt caactcttgg aactttggga acatggagca
    52921 gtacggataa ataaagttga tgtagacagc aaagaaaatc gcggtcgata tgtcacaaag
    52981 tattttgaaa aagggattgg acaagaattg ttggaaaact tcggaaagca agcctatttt
    53041 tcatcacgca acttaaaaaa gcctgatgaa gatagatttt atacttatga agattttaat
    53101 tatgatagtt cagtcgtact atatgaaacg gaatacatta gtaaagtcta taaagacggt
    53161 cagtatttcg ataatcatgt aaagtataag aaaataaaac tagattaata aaggagtaag
    53221 ttacatgata gcaactgtta ctaagaatga cctagttgcc cttggtttct ctgagggaac
    53281 atctaaacgt attatccgcc aagggaaaga gctactgata acacgaggct ttacagtcta
    53341 tcagaataaa cgaattggta ctatacctgc tactattgta agcgaattac tcggttttga
    53401 tgttcaaaac agtaccctca aggagtaaaa tatggcaatt agaaaaggta aagacggtaa
    53461 ttggatagtt gatattagca acggttttga cccaataaca ctaaagcaac gtagaattgt
    53521 cagaaagggc tataagacaa aaaaagaagc tattgaagca gaacactact tacgaagtgt
    53581 agagttaaaa gaacgcttct atggggctaa aataactatc cccatactat atgaactact
    53641 aaaggaagaa gatagtataa atcatcgaaa agcaagctat atcaatacac aagataataa
    53701 ttacaacaaa cacatcaaag attatttttc tatggtatat aatgtcggaa aactaaccta
    53761 tgaagacatc taccaattta gagaacatct taggcaaaaa gtagctaaaa attctgataa
    53821 acctttaagc acaaacacta tcaacaaaat catgatttta ctcaaaaaga tttttgatgt
    53881 tggtttgcga aaaggctatt acacctccaa tccagcaaat ttgataaaaa agttgccaat
    53941 cgaaaaaaca aaaatgcagt tttggacagt caaagaattt caacattttt taaccttgtt
    54001 tgaaactgaa gaatataata tcaagttact ctttactgtt ctattcttta caggactacg
    54061 acttggggaa gcattagcac taacatggca agacattgat tttacaagca atacaattca
    54121 cattacaaaa tcagtttatg taaacaaagg aataagtcat gttagcacaa caaagactaa
    54181 agctggaaca agaagaatta tcattaataa gaaattgagc catgaactac aacaatggca
    54241 acagaaacaa aaacacctat tagaacaatt tactagtgat agcatgaccc tacaagtgtt
    54301 tcaaggctca cctattacaa ttacaaaaaa tgcagttgaa aaacaatata agaaaatact
    54361 tgaacgtgat agcacactaa aaaaaatacg catacacgat tttaggcact cacacgcttc
    54421 cctgctgatt aaccaagggg aagattatct agttgtaaaa gagcgactag gacatgcttc
    54481 tataacaacc acgattgata cctactctca cttgtaccca agtaagcaaa aggatttagc
    54541 tgataaacta gatgatttac tataaagtaa ttgagtttta taaatggaaa gtttataatt
    54601 aaatcatgga tacatcacaa gtaataaaag cacatgaagt agctaaaaaa gcacactttg
    54661 gacaaattga tagagcagga attgactaca ttaaacaccc tgaaacagta gatagttttg
    54721 tcgcaactga tgaagagaaa gctgccgcct atctacatga tgtaattgaa gatacttcac
    54781 taaccctact agacctaaaa aaggaaggtt tttcaaaaaa cattatagaa gccgtcgata
    54841 tactcacaaa gaaaaaagga caagattatc aatcttatct caatctagta aagaaaaatg
    54901 aactcgctag agttgtaaag ttggcggatt tacggcataa ttcagattta acaagactac
    54961 cattaattac tgaaaaagac ttagagagaa ataagaaata cagttctgct attagatttt
    55021 taagagcaaa gaaaaaaagt tagtaactaa actataaaat tttataaaga gaaaacaaaa
    55081 gacaaggctt ataaactttg tctttattac tatactggcg gtcggtctcg aactggcata
    55141 tccttgcaga tactacaatt ttattaaaat aaataactat aaaaagtgaa attttttatt
    55201 gagaaaattt tagactagga gtataatgta tctaaaataa ctattaggtg gctgttatat
    55261 gaataatgtt gttactacac aaatttctat tcaacttagt caagagttaa attctttatt
    55321 aaatgctatt gttgaagaaa ataatacaac aaagactgac tttattagac aagcttttat
    55381 agagaaaatt gaagatatgt atgatattaa ggtcgctgat gaagcttata aaaaatgggt
    55441 tgaatgtagc aaaaaatcta tctcacatga agaaatgatg agacgctatg gctaaattat
    55501 acgcaatatc tgatatacat ggatacttgg atgaattcag agacgctctc aataaagtaa
    55561 atttaaacga taaagataat cgcctatttt tactaggaga ttatcttgat aatggacttc
    55621 aatcttttca agtcatttcc aaaataatcg aacttgagga ggtttatcct aatcaaatta
    55681 ttactcttct agggaatcat gaagaatggt tttatgattg gttgatttta gataaaccta
    55741 ctgcttcagc atttccagaa acaataaaaa gcttcttctc tccagagaaa ttgaactata
    55801 tttttaaatc gaatgctaac aactttgaaa cagatgttag aaatgaaatt aaaaataata
    55861 tcaaattcaa cccatttata aactggttta aaaaacgata tagggatgaa cgctattatg
    55921 aaaccgaaac ccaaattttt gtccatgctg gcattgatga agaagcagaa aagctttgga
    55981 aagaactaac gagttcagag atatttacaa acaaatttct tattaccact ggtagatttc
    56041 ataaagctat tatttcgggc catattgctt cttgggaagt agctaaagat agaagatacc
    56101 taggtaagat ttactatgat agtaaaagtc attactttat tgatggagat gtaacgaata
    56161 gcaaaacaat acctgttctt tactatgata caattaccca aaaatatcac tttctataac
    56221 t
//
LOCUS       DAVDZK010000010        52142 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVDZK010000010 DAVDZK010000000
VERSION     DAVDZK010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52142
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.010"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(102..1229)
                     /locus_tag="VUX16_000692"
     CDS             complement(102..1229)
                     /locus_tag="VUX16_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET8123699.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKKDSQTRVVKKGTKPQVLVQEIPIETEYLDGPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(1944..2495)
                     /locus_tag="VUX16_000693"
     CDS             complement(1944..2495)
                     /locus_tag="VUX16_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8123700.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(2744..3568)
                     /gene="nadE"
                     /locus_tag="VUX16_000694"
     CDS             complement(2744..3568)
                     /gene="nadE"
                     /locus_tag="VUX16_000694"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET8123701.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(3565..5025)
                     /locus_tag="VUX16_000695"
     CDS             complement(3565..5025)
                     /locus_tag="VUX16_000695"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET8123702.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(5141..5629)
                     /locus_tag="VUX16_000696"
     CDS             complement(5141..5629)
                     /locus_tag="VUX16_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123703.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(5619..5828)
                     /locus_tag="VUX16_000697"
     CDS             complement(5619..5828)
                     /locus_tag="VUX16_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8123704.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(6214..6393)
                     /locus_tag="VUX16_000698"
     CDS             complement(6214..6393)
                     /locus_tag="VUX16_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123705.1"
                     /translation="MMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQYLVVITTII
                     LLCFFTLKKSKKYSF"
     gene            complement(6726..6935)
                     /locus_tag="VUX16_000699"
                     /pseudo
     CDS             complement(6726..6935)
                     /locus_tag="VUX16_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773444.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6951..7796)
                     /locus_tag="VUX16_000700"
     CDS             complement(6951..7796)
                     /locus_tag="VUX16_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123706.1"
                     /translation="MEVINVSKHYGHSIILKDINFALNKGEIVGQVGRNGVGKSTLMK
                     ILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLI
                     QELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVL
                     KNLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSAT
                     DRDIFITKQEFGDIVQEEGLSITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIY
                     LNRSK"
     gene            complement(8179..8907)
                     /locus_tag="VUX16_000701"
                     /pseudo
     CDS             complement(8179..8907)
                     /locus_tag="VUX16_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(9167..9478)
                     /locus_tag="VUX16_000702"
     CDS             complement(9167..9478)
                     /locus_tag="VUX16_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123707.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(9493..10779)
                     /locus_tag="VUX16_000703"
     CDS             complement(9493..10779)
                     /locus_tag="VUX16_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET8123708.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDNIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            11403..11585
                     /locus_tag="VUX16_000704"
     CDS             11403..11585
                     /locus_tag="VUX16_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET8123709.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLCFNEKFGTENT"
     gene            11595..11957
                     /locus_tag="VUX16_000705"
     CDS             11595..11957
                     /locus_tag="VUX16_000705"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET8123710.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEHLRAVTGID
                     LLSILTDIANKKTGVKSK"
     gene            11954..13144
                     /locus_tag="VUX16_000706"
     CDS             11954..13144
                     /locus_tag="VUX16_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET8123711.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSIEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIADHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(13325..14551)
                     /locus_tag="VUX16_000707"
     CDS             complement(13325..14551)
                     /locus_tag="VUX16_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET8123712.1"
                     /translation="MAKTRYSGVFVDTKGKYFYETELGIDRISGKRIRKKSRKDSNGK
                     PFSTAREAYLELTRVKREYHKAHTYANYNMTVKQFILDCYIPYYKSYVEESTYAVRIK
                     NLEKIAERFYNKTLRGLTIEDIQNYRIWLLSSKDENGSGYSQAYASLIFGMFRKSLDY
                     AVEMGYLETNISKKAKAIPKGKAIVPYWTKVEFERVIAQICLDDFYEHLNFVMLWTFF
                     MTGIRVNEGMALWWNDIDFDKKRMRVHHMLILKSRKNWQRNAYTKTSDGKRIISLDDD
                     TISILKRWKDRQKEIGLGNETDFIFTYDSLPMIKSTLARIIQRYSELANVKRIQGKGL
                     RHSNASYLINEFNVSVLILSKRLGHSSPEITLKHYSHLWRGADESIAEIMSGNISIHT
                     APKTKIQFNGNQNLKR"
     gene            complement(14555..14749)
                     /locus_tag="VUX16_000708"
     CDS             complement(14555..14749)
                     /locus_tag="VUX16_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HET8123713.1"
                     /translation="MKPLISKDDLIKLGYKKHTAISIIQAVKQDLVYNKGIPFYNNRR
                     LGLVPRERVENLIGVKLDEE"
     gene            complement(14757..15569)
                     /locus_tag="VUX16_000709"
     CDS             complement(14757..15569)
                     /locus_tag="VUX16_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123714.1"
                     /translation="MTRELYNTKIIQYNSNTFEVIYYRKAKFRRLGETDTTVSNTSKS
                     PSEKELYQQANRIKRRIRHYMLCNDFDLFWTLTFNDEKINSHDYLIVKKKIRTWLKAQ
                     REKYGKFHYIFIPELHKNGRLHFHGVTGGFSPKLTKARNTKTGRLINKNGKQVYNVDS
                     YQLGFSTVTKIDSSEKVANYITKYITKDLLAIPSGYKQPKYFSSRGLIKPIVSYENLE
                     RNYFEGLTPSFSVGHLDNLEYKEDIAIYNLSIDDNEEIIQNSTDTRIKIRKE"
     gene            complement(15673..17082)
                     /locus_tag="VUX16_000710"
     CDS             complement(15673..17082)
                     /locus_tag="VUX16_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HET8123715.1"
                     /translation="MIVSKIKRKLSKYDCREYTPTYLSVSETIESRKERQYSLIKKLL
                     KVFLISVIITFLSSHFPLLSTIYKISIVISSVLLDIFIWYIVVKFLFSTYSPIWKYRF
                     LSILRLATERLDLIQLPSNKIQIKTVEWKFYKENERIIIELNPSGTIPNIQQVKEITR
                     RLTEFLIQATNEDWNILESTVQNSYVVIKYGKSNPRYTVSELFKITDEDYYINYKPIK
                     LYDNICFDIASEANQQIIIAPSGAGKSLYLATLAGLLIKQGHSISLIDAKQTSLGATF
                     ENLGIPVARNAEEIILLLEQMVFEMEDRYKRYFAFSSVDFGTTYKHFSLPAHYLIFDE
                     VLAALECGTSAQQKEMVRLLKILALKSRASGQGLLVLASQKLLASDLPRAVTEQCQTR
                     IILGNSSSISEETFYSVMGKEKIDLLAEYRGGVGKGYILTPKTNGIKYFETPYFDLDS
                     IDFKNKIRDFQTIPRKQIE"
     gene            complement(17079..17516)
                     /locus_tag="VUX16_000711"
     CDS             complement(17079..17516)
                     /locus_tag="VUX16_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123716.1"
                     /translation="MENNFGKVSFNSPSLKNLLIGTSNVEHTPTSAFVIECRDVPKRN
                     EKNEVIDGTISKKVLLALQSEIVKAIQEVGGDLSSIKPFTIEIYNDESFLKKINNELI
                     IAKTIDLEGALLALKWVSDGRNGGAYREFKLIISEIKLSGAKS"
     gene            complement(17701..18387)
                     /locus_tag="VUX16_000712"
     CDS             complement(17701..18387)
                     /locus_tag="VUX16_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123717.1"
                     /translation="MSSKQFNNLCKQKFPNSCHFIFKKCSQRIQKKYKDLKLKRHIDL
                     HSDEKLIGKILNYSNLSDLSRNNPYLITPSVLNYFVNEEHYFNDENEVLWGRDIDEYL
                     EDFFIEMILDIQGIPEYSKHLLNLSLTNTGDIKEYFQQHFPLASSSYNELKDKFIDFT
                     YNQFDTIEILENDSVFLFRKKDSVTLSPKNKESYLSYQKLPEKLDLLAKYILLPMIDK
                     LTLESLIYRK"
     gene            complement(18392..18607)
                     /locus_tag="VUX16_000713"
     CDS             complement(18392..18607)
                     /locus_tag="VUX16_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000626832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET8123718.1"
                     /translation="MISYKPFYETLFKQGKTEYELIFHHGLSSNTLHRMKKGKPITTA
                     TLDTLCFILNCNVYDVITYIPDDIEEV"
     gene            18722..20086
                     /locus_tag="VUX16_000714"
     CDS             18722..20086
                     /locus_tag="VUX16_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123719.1"
                     /translation="MKLEDFQTFPFKSVQEYISDKEKAIKFSFLLQGDEPDRSELMKL
                     IYKDIFEWYDDKVHSGDTLITYRTAIFRKYYGKSYSKLSRDKQREILNIIKSYTEYDD
                     DFPFEFELDNKEKNVYQICNNYQIGNFGIFPKGRINPKRAQSPYNDYFDLTLSVIWDL
                     YDGTLTPDDEFKRAILDEKEYFDQFKDFETFLSDNFLTVFFDDEGYLIRLSEIDDFEE
                     YVRISNQIIYTRGLAILTYLQSMYDDNSELPTQQLEEKKTVPRPTTKELAHRTLKIAE
                     EEIDKISKFDEYYNELEFNLHKEKFETTKKRIYGAIVLFLFIVSLFFYTSEIIMFIWI
                     LSTVLYVADKIRIVKEKIKYDKIINATQEKYREEKKKLLSTLRKEYYSIPTEFRTYNH
                     ISGIQYFLNADIASNLQQAIHYYSNEYNSKRMQDQIYSLHHSNTILQDRIKELELERE
                     LEKY"
     gene            20107..20499
                     /locus_tag="VUX16_000715"
     CDS             20107..20499
                     /locus_tag="VUX16_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123720.1"
                     /translation="MTKFNLQSNQIYSELSKFEIEEILYNATKQLNGSVERQSSEEIS
                     YSGQGNFFDYMKHPGLSRYTCWQVLVTISDLGDKRKVELTAVGESPISYLLNNFLSFI
                     TFYTLFQRHRNLNFGISKEKAKYLSNLL"
     gene            complement(20685..22247)
                     /gene="guaA"
                     /locus_tag="VUX16_000716"
     CDS             complement(20685..22247)
                     /gene="guaA"
                     /locus_tag="VUX16_000716"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET8123721.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREINPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPSDFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIQK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRVLGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            22389..23087
                     /locus_tag="VUX16_000717"
     CDS             22389..23087
                     /locus_tag="VUX16_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET8123722.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(23130..24026)
                     /locus_tag="VUX16_000718"
     CDS             complement(23130..24026)
                     /locus_tag="VUX16_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET8123723.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMILAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLIPLKDLFLEK"
     gene            complement(24035..24970)
                     /locus_tag="VUX16_000719"
     CDS             complement(24035..24970)
                     /locus_tag="VUX16_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET8123724.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKVGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(24967..25692)
                     /locus_tag="VUX16_000720"
     CDS             complement(24967..25692)
                     /locus_tag="VUX16_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET8123725.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLVSISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(25776..26411)
                     /locus_tag="VUX16_000721"
     CDS             complement(25776..26411)
                     /locus_tag="VUX16_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET8123726.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(26413..27240)
                     /locus_tag="VUX16_000722"
     CDS             complement(26413..27240)
                     /locus_tag="VUX16_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET8123727.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(27262..27598)
                     /locus_tag="VUX16_000723"
                     /pseudo
     CDS             complement(27262..27598)
                     /locus_tag="VUX16_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(27599..28315)
                     /locus_tag="VUX16_000724"
     CDS             complement(27599..28315)
                     /locus_tag="VUX16_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HET8123728.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRVQAPLVIKEVNGIKVALLAYSYGFNGIEQYISKEDYNRYLSD
                     LNEDKMKAEIERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSEMVEKDGDKKLIIY"
     gene            28828..29439
                     /locus_tag="VUX16_000725"
     CDS             28828..29439
                     /locus_tag="VUX16_000725"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET8123729.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            29484..30212
                     /gene="rlmB"
                     /locus_tag="VUX16_000726"
     CDS             29484..30212
                     /gene="rlmB"
                     /locus_tag="VUX16_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET8123730.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNLEKVKELAT
                     EKKVSISWISKKSLSEMTEGPVHQGFVLRVSEFAYSELDCILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(30251..31162)
                     /gene="trxB"
                     /locus_tag="VUX16_000727"
     CDS             complement(30251..31162)
                     /gene="trxB"
                     /locus_tag="VUX16_000727"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET8123731.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(31228..31452)
                     /locus_tag="VUX16_000728"
     CDS             complement(31228..31452)
                     /locus_tag="VUX16_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET8123732.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(31530..32273)
                     /locus_tag="VUX16_000729"
     CDS             complement(31530..32273)
                     /locus_tag="VUX16_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET8123733.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(32273..33073)
                     /locus_tag="VUX16_000730"
     CDS             complement(32273..33073)
                     /locus_tag="VUX16_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET8123734.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMDISAPDTVQTDVKGDLR"
     gene            complement(33231..33587)
                     /locus_tag="VUX16_000731"
     CDS             complement(33231..33587)
                     /locus_tag="VUX16_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET8123735.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNREAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(33581..34111)
                     /locus_tag="VUX16_000732"
     CDS             complement(33581..34111)
                     /locus_tag="VUX16_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET8123736.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGEPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(34111..34605)
                     /locus_tag="VUX16_000733"
     CDS             complement(34111..34605)
                     /locus_tag="VUX16_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8123737.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            34740..35186
                     /locus_tag="VUX16_000734"
     CDS             34740..35186
                     /locus_tag="VUX16_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET8123738.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYINQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            35183..35830
                     /locus_tag="VUX16_000735"
     CDS             35183..35830
                     /locus_tag="VUX16_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET8123739.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMITGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(35851..36432)
                     /gene="pdxT"
                     /locus_tag="VUX16_000736"
     CDS             complement(35851..36432)
                     /gene="pdxT"
                     /locus_tag="VUX16_000736"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET8123740.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(36433..37308)
                     /gene="pdxS"
                     /locus_tag="VUX16_000737"
     CDS             complement(36433..37308)
                     /gene="pdxS"
                     /locus_tag="VUX16_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET8123741.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLRKDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(37460..38839)
                     /locus_tag="VUX16_000738"
     CDS             complement(37460..38839)
                     /locus_tag="VUX16_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET8123742.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            39134..40057
                     /locus_tag="VUX16_000739"
     CDS             39134..40057
                     /locus_tag="VUX16_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET8123743.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            40117..40722
                     /locus_tag="VUX16_000740"
     CDS             40117..40722
                     /locus_tag="VUX16_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET8123744.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDVIFDDFRIFVKITEKLRNAQELLRKDAEEFNWENL"
     gene            40740..41984
                     /locus_tag="VUX16_000741"
     CDS             40740..41984
                     /locus_tag="VUX16_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET8123745.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(42101..42358)
                     /locus_tag="VUX16_000742"
     CDS             complement(42101..42358)
                     /locus_tag="VUX16_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET8123746.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRVV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(42400..44436)
                     /locus_tag="VUX16_000743"
     CDS             complement(42400..44436)
                     /locus_tag="VUX16_000743"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET8123747.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGGRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYALLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTLKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(44696..45613)
                     /gene="glyQ"
                     /locus_tag="VUX16_000744"
     CDS             complement(44696..45613)
                     /gene="glyQ"
                     /locus_tag="VUX16_000744"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET8123748.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQCCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(45806..46567)
                     /locus_tag="VUX16_000745"
     CDS             complement(45806..46567)
                     /locus_tag="VUX16_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET8123749.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QPVIWSDFNAATQIIRESAVPTYTNNRRVVMTPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLHIVGHELAHWSEHFLDDFDGSDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTDKTLPLLNWFVQQKLIEKEI"
     gene            complement(46840..47682)
                     /locus_tag="VUX16_000746"
     CDS             complement(46840..47682)
                     /locus_tag="VUX16_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET8123750.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTTAVQSGAPRVD
                     DVDF"
     gene            complement(47796..49187)
                     /locus_tag="VUX16_000747"
     CDS             complement(47796..49187)
                     /locus_tag="VUX16_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET8123751.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYGIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(49422..49799)
                     /locus_tag="VUX16_000748"
                     /pseudo
     CDS             complement(49422..49799)
                     /locus_tag="VUX16_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            50032..51009
                     /locus_tag="VUX16_000749"
     CDS             50032..51009
                     /locus_tag="VUX16_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET8123752.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGKQVQLPIQQAPHT
                     MTEEVAAFSHMIQQPDLNLYQTWLDDAGSVHELLYTMRQTAGIRFEAEK"
     gene            51006..52088
                     /locus_tag="VUX16_000750"
     CDS             51006..52088
                     /locus_tag="VUX16_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET8123753.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGSEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLNNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
BASE COUNT        16059 a        10902 c         8901 g        16280 t
ORIGIN      
        1 acttttttat agtcgctata agatgacctt atctatagct ttttatatat aattatatat
       61 tcagacatac tattatcaat tttgtcgcag ggaggaatct gttaacgcac ccattcacca
      121 ttatcattga ctctatagcc atctatactt gtattgaccg ctaactcacc cgatgcattt
      181 acataatacc atttaccacc aacttggaac cattgattaa ctttcataga accgttgctg
      241 ttgaggtagt accatgaacc attaacttgt acccaacctg ttgccatgga accatcagta
      301 ttataaaaat accacatacc attttcttgt ttccagcctg ttgttggagc aactgcttta
      361 gctggttcta ctgctacatc tgttccttgg ttagatgtaa cagatacagg atacgaagga
      421 atagatgatt gctcaggaac aacaactttt tcaggttctc tcgtccctct ccttatacgt
      481 ctttttacca tctctttagt aatttgacga gaagtagttt cttcaattgt tccatcacgt
      541 tcatctacag catagattgt agtaagagta attttaccaa tttctcctac ttcttgacct
      601 ttatcaagag ttgggccatc gagatattct gtttcgattg gaatttcttg gacaagaact
      661 tggggcttgg ttcctttttt aacaactctt gtttgagagt cttttttttg acttaaagta
      721 ctctcagtta cttgtccact ctttccatct acatcataag ttatcgttgt aactgttttc
      781 ccattctttc ctagagtaat ctcttgctcc tgtcctgcag aaaggtcatt gtctgcttca
      841 tatttagtag caaatggaac aagaacttct tcaaccttgc ttttagctgg aactttgata
      901 actgtatccg tggcttcttt tctatcaaca gtaacctgtt cggtaacatg accagtctct
      961 ggattaacat cgtaggtcct tgtcgtagtt acatagccat cctctccatc aattgtaaca
     1021 ggattttcac tacggtcttt tgtttcatct ttttcataac gaattcgcgt acttgaaatt
     1081 ttcttggtta ctaccttagg tttagtcgct acttttacaa taatatcccc attgtcagcg
     1141 tcatcatact ctattccctc ttctttatct ctagtatcat ctctgacata ttgaatccca
     1201 tcagcagcat gaacaaaact tgtattcaga ttcctcctaa aaataaactt agcccgatta
     1261 ccgcagaacc aaaaatcttt ccgagtttac gtattgcata gcgcttatta gtattagatt
     1321 ttgccattac atcctacttc tagtatagca tcttttctat caaacgttaa acaatatact
     1381 ttatatataa aatagactta gaatgatata ttgattattg aactaacact ttaactatat
     1441 cgtaatcaat ctcatatata aaggattgca gacatcttat ctaaatacat gctaatatat
     1501 ttagatacaa acattccaac ttgataattt tcactcatct ttcatcattc cttatacaac
     1561 tatgcagtat aaatagaata gttttctcat cagaatgaga ctattttaat attagataat
     1621 ttgatagaaa aaacatgaat aaaattggtt gaatttaatt ccctaactcg atagaggatt
     1681 ctattttaaa tttaacaaca gctaggatta cactataaaa agtacattac cacctgttcg
     1741 gctggagaat ctagtcgatt agctccctct tagttacaag cttaaagcga ttttttaact
     1801 aatactaaac cagattaaag aaggaactag aacatctgtc ttgtactaat caatatgcta
     1861 ttttaaagtt tcaaataaac ttggaatgct aattattata tttacaataa atagttgact
     1921 tcgatagaaa cagaaaatag aattcaacat tcttccctac ttataccata ataaataaga
     1981 tccgcaagat agccttttct ctctacacca ttaacaatgg tttgtagata ggacattcca
     2041 gccttttcca tgacacgacc tgaagctggg ttgagactgg cataacgtgc tctgaccttt
     2101 tgaaaacctg cttgagtaaa acaaaagtcc aagatagctt tcaaagtctc tgtcatcata
     2161 ccatttcccc agtaagcctt gcctaacaca tagccaattt cacagcttaa atcagcctcg
     2221 tctatcttaa caatgctgat atctcctatc acttgctctg ggttttcttt tagacaaatg
     2281 gcccatttat aatagttgag attagtatag gaagcaaccc aattgcaaat cgagtttcga
     2341 gtgatttcga catcaggatg gggatcccag gtaacatagg tcagattctc agcggatgaa
     2401 gcccaatttt gaaacatggc ttctgcatca ctctccacaa atcttcttaa aatcaaacgt
     2461 tctgtctgta atatttgcgt accgatagat ttcatgatgc tacctcactt ccttatttct
     2521 atgctcgtag taaaaaggct caactcagta acagctagaa aacgagtttg tcttctaatt
     2581 tcttgacgca gtcgctgcct ggtttgaaat gcgctctagc aatctttttc aaacctagtc
     2641 atcgttgcag gggtaagacg atgaaatcga actcttcgag ttaccgaatc tgcctcattt
     2701 tcttatttca agataagagg ctgaaaacct ccaatggagg tttttactcc caaaagtcat
     2761 caaatacagt gatgggtaag tggcgtttgt gttggccttt gtgccaccag ttttcaatgg
     2821 tcgcttgagc ttctgggctg attgttttgc cttctaggta atcgtcaatc tctgcatagg
     2881 tgactccaag tgcgacttcg tcagctaggc ctggtttgtc ttcttctagg tctgccgttg
     2941 ggattttttc ataaagggct ggctctgcgc caagtttctg caagagctgt tttccttggc
     3001 gtttattgag gcggtaaaga gggagaatat ccgcaccgcc gtcaccaaac ttggtaaaga
     3061 aacctgtgat attttccgcg gcgtggtctg ttccaatgac cgctccgcta tgggaaccag
     3121 caagggcata ctgagcaatc atacggcaac gtgccttgat attccccttg ttgaagtctg
     3181 aaacaggact acctgtcgct tcaactgcag ctgtcatggc atcagctgac tccttgatat
     3241 tcacaaccaa gctgacatct ggctggatga aggctagggc tttttgagca tctgcttcat
     3301 cagcttgcac tccgtatggc agacggacag cgataaattt gtagctgtcg tctcccgttt
     3361 cagctcgcag ttcttccata gctaattgcg ccaaacgccc tgccaaggtt gagtcttgtc
     3421 ccccagaaat ccctagtaca aaggttttta ggaagggatg ttttttcaga tatcttttta
     3481 agaaatcaat agaacgacgg atttcttcct gggcatcaat cactggtttg acacccagct
     3541 cttggataat cgtttcttgc aaactcattc ttcttctcct tcaccaaggg cttccttgcg
     3601 catcttatca atcaagtcca tcttatcttg ccatacatca cgcgccaaat ccactggata
     3661 gtgctgcgga ttgagcacac gcttatactc atcccacaac ttgtcaaatt ctttacgggc
     3721 ataatcctga atgtcagtca aactaggcaa gttgtaaact aatattcctt ctttgaagat
     3781 atccaccaag agaggaacgg catcaaaatt acgaaccgtc ttcttgatgt atgtataggt
     3841 cggatggaac atcttgattt ctgtcatgtc gctaatatcc acaccatcat aagtgatata
     3901 gtcgccttct gacttgcctt tttcacgact ggtaatgcgc cacacctgct tcttacctgg
     3961 cgtagagact ttttccgcat tattagacag cttaatcgta ttgcgcatct gaccagtttc
     4021 atcttcgatt gcaacaatct tgtaaactgc accaagagct ggctggtcat aagctgtaat
     4081 cagcttggta cccacgcccc agacatcaat cttggccttt tgcatcttga ggttgaggat
     4141 agtattttcg tccaaatcat tagaagcata aatcttagcc tctgtaaatc cagcctcgtc
     4201 cagttgctga cggactttct tagaaatgta ggcaatatcc ccagagtcaa tccgcacacc
     4261 cataaagtta atctgatcac ccagctcacg cgccacctga atggcagctg gtacaccgat
     4321 gcgaagggtg tcataggtat ccacaagaaa gacacaattt ttgtgggtcg cagcgtaagc
     4381 cttgaaagct tcatagtcat tgccataaac ctgtaccaag gcatgggcat gggttcccaa
     4441 aacaggaatg tcaaagagct tacccgcacg cacgttgctg gttccattgg caccaccaat
     4501 caccgctgcg cgtgttcccc agatggccgc atccatttct tgagcccgac gtgtcccaaa
     4561 ctccatcaag ggttcatctt cgataaccga acgaatacga gctgccttcg tcgccaccaa
     4621 ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc aactgacatt gggctagagg
     4681 tccttccacc tgcacaatcg gttcattagc aaaaaccaaa tccccttctt gggcagaacg
     4741 aacggtcaac tccaacttga aattgcgaag gtaatccaag aacgccccat gataaccaag
     4801 cgactccaaa taggctatat cactatctga aaaacgcaag tcttcaagat agttcacaat
     4861 tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa ggctgttggc ggaaatatac
     4921 ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag taaacctgca tcatgttaat
     4981 ctggtacaag tccgtgtgca atgtcaaact atcatctgga tacatacttt tcctacttcc
     5041 ttagctagaa acccatgaaa attttcaaga actttcatgt attccaataa attagtacta
     5101 ttatatcaca ttttagctgg attgagaaaa gagtaacaag ctattctcca ctctccaatt
     5161 catccatatc ttgttcaaat tttttctgag cccattcgcc atagctctta agaccaagat
     5221 tgccaataaa gacccatgga aggtaaatga tataagtaat gacccaagca gacaggtatt
     5281 taaaattcaa aggattgtgc tgataaattt ctatgttgaa ttgataattc tgcaacatca
     5341 aaagagccgt aatagccaag gttaggaaaa aacaacccaa aatcgtaaaa tgaaaacgac
     5401 tatagtaggt cactcccaga taacgggcac gattgaaaaa gtaaaatgtc cctatgatga
     5461 taacgattag cagcatatta gaattaaaaa ggcttggtgc taatactgaa atgatataag
     5521 ataggagcga caaagcaatg cagatataga aactttcaga gcccgcttta ttgaacagtt
     5581 gttcttctct ttcgtctagt aattgataat aataaaatct atttttcatc ttcttcctcc
     5641 caaaatagtt ggtctagggt tttccctaaa catctgcaaa tagactggca gagcgagaga
     5701 ctgggattgt attttcccgc ctctatcaaa ccaatagtct ggcgtgtcac cccgacagcc
     5761 tctgccagtt gaccttgtgt taaatcacgc tctacccgag ctaattttaa ttttaaattt
     5821 ttagccacct tcgtcctcct tatagtttta atactcatct actcttaaaa aatccaaaac
     5881 caacacaagc tatcagctat ttattataac cccattaatt tgcactccag tattatcttc
     5941 agccgaaaat cagtatttta ggttgtttga aataaacttc ctagtttact cttttatttt
     6001 tatttagtat tagctttagt aggatctttt aaacgagttt ttattgctta tatttcttgt
     6061 ttagtttagt tggtttcata tcactattat ataatgcttt tggaaatgag cctagtataa
     6121 gtcaaaaacg tgttgaatag tgaaagcagg agcataccaa gatgactgat ttttttattg
     6181 tattttaggt atgcaaaata atactaaatg aaactaaaat gaatacttct tgcttttctt
     6241 gagagtgaaa aagcacaata aaatgattgt agtgattacc acaagatact gactaataga
     6301 catcgtattt gaagccacaa atacaggtaa agaataaaaa ggaagaagtt caattgcttt
     6361 gataaacaaa tcattactag tattcatcat catcgtattt aatatattag ggataaagag
     6421 tagtaaagct actaaaatac caagccactt ttcaatttgt ataaatagaa aatgtaagat
     6481 aatagaaaat aaaacaggac taacaaaatt gtattgacta caatagctac tataaaatct
     6541 aatcctaaat cacctggaat acccaattta cttactatga ctagtaacac aatgccattc
     6601 aaagcataaa taatggaaac tgagatggca tatagaaaat tagacaagac gtaaatcatc
     6661 cgattcttct gttgattata aaacaaactt accgtattgt gggaaaaatc tctactaatg
     6721 actcgattag catgtataac agccattaac ataccgagca tagcataaaa gtttgaaata
     6781 tgcttaatac caagcgatgt cccttgagtc tttagaataa agaatgtaac caatatcggc
     6841 ggtataaacg agataagcaa accgagatat attacgcctg atgaatataa atttcttata
     6901 ttttccttaa gaaaattaaa tttatttaat ttcatgatta taaccttcct ttattttgaa
     6961 cgatttagat aaatatcttt gagcgtctct tttttagttt caaaatcaac tactttaata
     7021 gagttttcgt taaaaaattt aaaaagctca ctactttgaa tattcccaga catagtaatg
     7081 ctcagtccct cttcctgaac aatatcccca aattcttgtt tggtaatgaa aatgtctcta
     7141 tctgtagctg atgaaaaagc tatctcaaac aagaaattat gactatcttt tcctactttt
     7201 tgaaatgtca aaagcccgtt ctccaagaaa agaaccctct cacaaatttc ttcaatatct
     7261 tctaatttat gactcgatat taaaattccc acattttcat gtaaagctaa attttttaga
     7321 accgataaaa ctatttgtga tgattcaata tctaaaccat tagtcggttc atctaaaatc
     7381 aatatatcag gttccgtaac gagagttaga agcaaagcta atttttgttt tgtacccaaa
     7441 gaataggtct ttactttttt attaatagac tgagtcaaat ctaactcttg gatcaaactt
     7501 ctaaatcttt cttgattgta gtcaacacca tataaatttg acaaatattt taaattctct
     7561 aaacctgttt tagataaaaa taattttggt tcttcgatta aatacccaac attatcactg
     7621 cttataatat tacctgaagt cggttgatta ttctgaacaa gaattttcat caacgtactc
     7681 ttaccaactc catttctccc tacttgacca acaatttcac ccttgttaag tgcaaaattt
     7741 atatctttga gaatgattga atgaccataa tgcttactta catttataac ttccattttg
     7801 taattcctcc attaatattc tcggttttct ctttgattct cattaatttt aaaaagttgc
     7861 gcctcttttt aacaacatta tatcatatat ctaacttaat gcaatatata aatgtcattt
     7921 tgtaaaattt tattaataaa aaactctcta caacaaaata atagagagtt ttctgcttat
     7981 taattttttt caaaatatct aagacatcgc ttctttgttt aatttgatag gctttgatac
     8041 ctaagctccg actttatcac ttaaaaaata aaaaaggaca gctaatctct tgcgcatcaa
     8101 gggatttcgc cattctttaa tctcgtttaa gtgttgtata tggagctttg cataattttt
     8161 taacactaaa caactacatt aagcacgaac tgtgacgctg gttccatctt ccttataaag
     8221 attgataagc ccctctttaa gagctcgaac catgtctcct gattgaacag gttgtgggac
     8281 tttaatagtc aatagttcca ttggatttgg agcgcggtcg attttattgc ctttggcatc
     8341 atgcaaatct tcaatatagg tttcaaaatg acggaaacct ggaccataaa actcaacttg
     8401 gtccccttcg ttaatgacat ttcgttgacg aatagttgct gtttgtgccg catcatcata
     8461 agaaaccact tcagcgacaa acttgtactc aggaatttta cgacgagcac caaacaactg
     8521 ctcattttca gatggtgtac catagtaaaa tcctgtagcc agttcacgtt gggcaaactt
     8581 ccacatctcg tccaccaagt cttgtttgat agcttcaaac ttttcaggac tttcaagata
     8641 ggcatccaca gccgccttgt agcagttggt tactgttaat acatagtgaa tagactccat
     8701 acgtccttcg atttttagac tgtccacacc attttcaatc atatctggaa tgtggtcaat
     8761 catagacatg tcaacggctg acattgaaaa ttcttctgga atctcaccct gcaaactctt
     8821 acgttctttc ccaaatggca tatcgtaaag gtcgtacttc caacggcatg actgagaaca
     8881 tccaccacgg ttggcatcac gcatactcta gacggattgt tttgacaatt ctaacctttt
     8941 agactttgca taataactgt taaacagtcg aaaattatcc cagttttaac aagtagtcaa
     9001 aataccagat aaagtaaaaa gaggctagga aaaaagtctt taaaatctta aaaacgcata
     9061 gtatcaggta ttgaacaatc ttgatattat gcgttttatt gtgggaagat ttacttcatt
     9121 ttctcttgga attgagtttt ctcctacttc aaaactagat gatctgctat ttaaaatagc
     9181 gttccttatg attttggcaa cctggattaa agcgagaaaa acaaaagagg caacttaagc
     9241 tttctttata ttgcttatat gttaatagtt ttagacaaac accacataaa ataggcttat
     9301 cctgtatcaa agataaggga taaggctcaa aagggtgatt ttctaatgaa tcatgacacc
     9361 gataacaagc ataatacttt ttacaatcat agcattgtaa agcaataata tccagcttgc
     9421 tatggtaatg aatgcatctt gtttgcttat ccactaagaa accctgtgcc tctatcattt
     9481 ccttttcctt tcttaagctc gaactgtgac gctggttcca tcttccttat aaaaattgat
     9541 gagtccttct tttaatgcac gaaccatgtc tccagcttga acgggttgtg ggactttaat
     9601 agtcaatagt tccattggat ttggagcgcg gtcgatttta ttgcctttgg catcatgcaa
     9661 atcttcaata taggtttcaa aatgacggaa acctggacca taaaactcaa cttggtcccc
     9721 ttcgttaatg acgtttcgtt gacgaatggt tgctgtttgt accgcatcat cataggaaac
     9781 cacttcagcg acaaacttgt actcaggaat tttacggcga gcaccaaaca actgctcatt
     9841 ttcagatggt ataccgtagt agaaacctgt tgccaattca cgttgggcaa ccttccacat
     9901 ctcgtccacc aagtcttgtt tgatagcttc aaacttttca ggactttcaa gataggcatc
     9961 cacagccgcc ttgtagcagt tggttactgt tgatacgtag tgaatagact tcatacgtcc
    10021 ttcgattttt agactgtcca caccattttc aatcatatct ggaatgttgt caatcataga
    10081 catgtcaacg gctgacattg aaaattcttc tggaatctca ccctgcaaac tcttacgttc
    10141 tttcccaaat ggcatatcgt aaaggtcgta tttccaacgg catgactgag aacatccacc
    10201 acggttggca tcacgcatac tcatgtggtt tgaaagagta caacgtccag agtatgaaat
    10261 acacatagct ccatggacaa aggcttcaat ttcaacatct gtacgtttgc ggatctcagc
    10321 taattcttcc attgaaacct cacgcgctaa aacgacacga gtcaagccta gctctttcca
    10381 gaactcaagg gtttcatagt tagtggcact ggcttgggta gaaaggtgga tttcaaggcc
    10441 tggtgcttca gtcgctgcaa tcataatcaa ggctgggtca gatacgataa ctgctgcaat
    10501 cccgatatca cgcagtttac ggaaccactc accagcacca gcttcatttc cttcgtgcat
    10561 aaccatatta gccgctacat agaccttggc accatacttg gccgcaaact gcacgccttc
    10621 ttccatctgt tcgaaagtaa agtttcccgc acggctacga agaccatagg cctgaccacc
    10681 gataaagaca gcatctgctc catactgaac agctaccttt agcttctcta aagtccctgc
    10741 aggtgataaa acctcaggac gttttaatgt ttttgtcatg atttctccta tttgcaatat
    10801 aaaagtttga catttttcct tctcatttta tagtaaataa aggataaaat caagcctaga
    10861 cggattgttt tgacaattct aatcttttag actttgcata ataactgtta aacagtcgaa
    10921 aattatccca gttttaacaa gtagtcaaaa agtctagaaa agtaaaaacc agtatccaaa
    10981 gatactgact cgtaaaaata cataaattag tccttagatg actactccca ctctgttgct
    11041 cctataatgg aaaaggattg atacagtcta gaatatcgct tttttattta ttattctgat
    11101 ataaaactgt tagaattgat tttttgtttt atacccaaat atgaatagag acgtagctaa
    11161 taagttgaat aacatatttg gaaaaatgag aaatagcaat attactagaa cttttagaaa
    11221 caatcaatat ttaaaaagaa aaaagctcaa agaatttatt aaaccatgtt ataatagata
    11281 tagctataat tttatttata acaagaggat agaaatgacc gaattagaaa gaaaaaatcg
    11341 aaaaattagc taagaaatat tctgataact taaacatcaa agttcaagag agagttcgtg
    11401 aaatggcaaa tgataataag agccattatt tgatatacag agttttaggt atttcatttg
    11461 aagaaggaga aaatatcgat ttgtatcaaa ataaaggtcg ttttttatac aaatatgctg
    11521 gttcattttt agaagaagct gcagtactat gctttaacga aaaatttggt acagaaaata
    11581 cttaaaaagt taacattcct aattctgaaa gtacaaaacc taagactttt gaaattgatt
    11641 gtttagtcgg agaaaaacac gcatacgaaa taaaatggtg ggatgcaact acagatggag
    11701 accatataac taaagaacac actagaataa aagttattca taacaaagga tatataccaa
    11761 ttcggttaat gttctactat ccaaatagaa ctcaagctat aaaaattcag caaactttag
    11821 aaacattgta taacggtatt ggagggaaat attatggaga ttctgcctgg gaacatttaa
    11881 gagcagtgac cggtattgat ttacttagta ttctaacaga tattgcaaat aaaaaaacag
    11941 gggtaaaatc aaaatgacag tattaaaagg agataactta gaaatattaa aaactattga
    12001 atcctcaagt attgatttaa tctatatgga ccctcctttc tttacacaga aaacccaaaa
    12061 attatctaat aacaaaaata ttatgtattc aatcgaagat acgtggactt cgattgagga
    12121 ttacaaagaa tttttgtctg taagattaga agaatgcaaa agagtgctaa aaaatagtgg
    12181 cagtattttc gttcattgtg ataaaattgc agatcatcat attagattaa ttttagataa
    12241 tatctttgga gcagatatgt ttcaaagcga aattatatgg aactataaac ggtggtctaa
    12301 ttcaaaaaag ggattattga acaatcatca aaacatttac ttttattcaa agtcaaaaga
    12361 ttttaaattt aatacaattt ttacagagta ttcttctact acaaatatcg accaaatact
    12421 agtagaacga aaacgaaatg gaaactctaa aactatatat aaagttgata ataatggtaa
    12481 ctatattcta gcaaaagaga aaaatggagt tcccctttca gatgtttgga atataccatt
    12541 tcttaatcca aaagctaaag aaagagtagg ttatcctaca caaaaaccta ttctgttatt
    12601 agaacaaatt ataaagattg ctactgataa aaatgatata gttttagacc cgttctgtgg
    12661 aagtggaact actttagtag cctccaagat tttgaataga aattatatgg ggattgattt
    12721 atctgaggaa gctatcaata taactcagca acgtctggaa aatgttataa aaacaagttc
    12781 aaatttattg aataaaggaa tcgaagcata tagaaccaaa actgaggaag aggaaaacat
    12841 tcttaaatta ttacaggcaa aaattgttca aagaaataaa ggaattgatg gttttttacc
    12901 taaacatttt caaaaaaaac cgatacctat aaaaattcaa aaaaataatg aatgtctgaa
    12961 tgagagtatc tctttattac agaatgctat aaactccaaa aaacttgatt ttggagtagt
    13021 tataaaaact cattcagata atttattatt tgattttgat acgattcctg aaaatataat
    13081 agtagttgac cattttgaac ttacaatcga aaaatggtta agtaaaagtc aacagttact
    13141 atagtttgca aattatttac agaaagaaca aaaaatgctc tgaaacactg atttcaaggc
    13201 attttttgtt agtttaaaat tactcccact caattaacaa tttcataggt ttagtgccag
    13261 aaaaccttga tttattaagg tttacaatgc cttttaaata tatttggcgg gatttctggc
    13321 ggggttatct ttttaggttt tgattcccgt tgaattgaat ttttgttttt ggagctgtat
    13381 gtatggatat attcccactc attatttcag caatagattc gtcagctccg cgccaaaggt
    13441 gtgagtaatg tttcaaagta atttctgggc tagaatgacc taaccttttc gacaaaatta
    13501 agacagatac attaaactcg tttatcaaat aagaagcgtt actatgacga agtcctttac
    13561 cctgtattcg ctttacatta gctagttcag aatatcgttg aataattcta gctagtgtag
    13621 attttatcat tggaaggcta tcatatgtaa atataaaatc agtttcattg cctaaaccaa
    13681 tttctttctg tctgtctttc caacgcttta aaatagaaat cgtatcatca tctagggaaa
    13741 taatacgttt gccatcactt gttttggtat aggcatttct ttgccagttt ttccttgatt
    13801 ttagaataag catatgatga acacgcatac gctttttatc aaaatcaata tcattccacc
    13861 aaagtgccat tccttcattt actcgaatac ctgtcatgaa aaaagtccaa agcataacga
    13921 aattaagatg ttcataaaaa tcatcaagac agatttgagc aataacacgc tcaaattcta
    13981 ctttagtcca gtatggaacg atagcctttc ctttcggaat agctttggct ttcttagaga
    14041 tattagtttc caaataaccc atttctacag cataatcaag agactttcta aacataccaa
    14101 agattagact agcgtaggct tgagagtagc cagaaccgtt ttcgtctttg cttgacagta
    14161 accatatccg atagttttga atatcttcaa tagtcaaacc acgtagtgtc ttgttataaa
    14221 atcgttcagc aatcttttca agatttttga ttctgacagc ataagtactt tcttccacat
    14281 acgatttata atatggtata taacaatcta aaataaactg cttgacagtc atattgtaat
    14341 tagcgtaagt atgagctttg tgatactctc gttttacccg agtcaattct aaatacgcct
    14401 ctctggcagt agaaaaaggc ttaccgttgc tatcttttct acttttcttt ctaatacgtt
    14461 taccactgat tctatcaatg cctagctctg tttcatagaa atattttcct ttcgtatcaa
    14521 caaacacacc gctataacgt gtttttgcca tttgttattc ctcatctagt tttacaccga
    14581 taaggttttc taccctttcc cgtgggacta gtccaagtct acggttattg tagaatggta
    14641 tacctttatt atacaccaaa tcctgcttta ccgcttgaat aatactaatt gcagtatgtt
    14701 tcttatatcc tagttttatc aagtcgtctt tactaatcaa tggtttcata cgcttactat
    14761 tcctttctga tttttattct tgtatcagtt gaattttgaa taatctcctc attgtcatct
    14821 attgatagat tgtaaatcgc aatatcttct ttgtactcaa gattatctaa atgacctact
    14881 gaaaaactgg gggttaatcc ctcaaaataa tttctttcta aattttcata gcttactatc
    14941 ggttttatta aaccacgaga tgaaaaatat tttggctgtt tatatccact tggaatagct
    15001 agtaaatctt ttgtgatata ttttgtaatg tagttagcaa ctttttcaga agaatcgatt
    15061 tttgtaacag tactaaatcc taattgatat gaatcaacat tatagacttg cttgccattc
    15121 ttatttatca atcgaccagt tttagtattt cttgcttttg ttaattttgg actaaaaccg
    15181 cctgttactc catgaaaatg aagccgtcca tttttatgta attctggtat gaaaatgtag
    15241 tgaaattttc catatttttc acgctgagct ttgagccaag tgcgtatttt cttttttacg
    15301 attaaataat catgggaatt gattttttcg tcgttaaaag ttaatgtcca aaataaatcg
    15361 aaatcattgc acagcatgta gtgacgaata cgccttttta tcctattggc ttgctgatag
    15421 agttcttttt cacttggact tttagaagta ttagatactg tagtatcggt ttctcctagt
    15481 cttctaaatt ttgcttttcg atagtatatg acctcgaaag tatttgaatt atattgaatt
    15541 atttttgtgt tatataattc tctagtcatt agtcctccgc ttatcatgcc tgcatgtcaa
    15601 gtagcaggct aatatacaca tctagcgagt cctggcttgc ttatgagcaa gccggctcac
    15661 tagatagtta gttcattcta tctgctttct tggaatagtt tgaaagtccc ttattttatt
    15721 tttgaaatct attgaatcta aatcaaaata cggagtctca aaatatttta ttccgtttgt
    15781 tttaggagtt aaaatatatc cttttccaac tcctcctctg tactccgcca aaagatctat
    15841 tttctcttta cccatgacac tgtaaaacgt ttcttcagat atactggaac tattccctaa
    15901 aataattcta gtttggcact gctctgtgac tgcacgcggt aaatcagaag caaggagctt
    15961 ttggcttgca agaacaagca atccctgtcc agaagcccgt gattttaagg caagtatttt
    16021 tagtagccta accatttctt tttgttgcgc tgatgttcca cattccaaag ctgccagcac
    16081 ttcatcaaaa attaaataat gtgcaggtaa agaaaaatgt ttgtacgtgg tcccaaaatc
    16141 aactgaagaa aatgcgaaat atcgcttata tctatcttcc atttcaaata ccatttgttc
    16201 tagaagtaga ataatctctt ccgcattacg tgcgacagga atacctagat tttcaaatgt
    16261 cgcacctaaa gaggtttgtt tagcgtcaat taaacttata gaatgacctt gtttaattag
    16321 taacccagct agtgtggcta gataaagtga cttcccagca ccactaggag ctattataat
    16381 ctgctgatta gcctcactag ctatatcaaa acaaatatta tcataaagtt ttattggctt
    16441 ataattgata taataatctt catctgttat cttgaatagt tcactaacag tatatcttgg
    16501 atttgatttt ccatatttta taacaacgta actattttgc acagttgatt ccaagatatt
    16561 ccagtcctcg ttagtagctt gaataagaaa ttcggtcaac cgccttgtta tttcttttac
    16621 ttgctgaata ttaggaattg tccctgaagg attgagttca attataatcc tttcattttc
    16681 tttataaaat ttccattcaa ctgtttttat ctgtatttta ttagagggaa gttgaattag
    16741 gtctaaacgt tctgttgcaa gtctaagaat gcttaaaaat ctgtacttcc atataggaga
    16801 gtaagtagaa aataagaatt ttactacaat ataccatata aaaatatcta acagaacaga
    16861 agatataaca atacttatct tgtagatagt gcttaataaa ggaaaatgtg atgaaagaaa
    16921 ggtaatgata acagatatta ggaacacctt taacagtttc ttaataagag agtactgcct
    16981 ttctttacgg ctttctatag tttctgaaac agataagtaa gtaggggtat attcacgaca
    17041 atcatattta ctaagtttcc tttttatttt agatactatc atgatttagc acccgataac
    17101 tttatttctg aaataatgag cttgaattct cggtacgcac caccatttcg accatcagat
    17161 acccatttta acgctaataa tgctccttct aaatctattg ttttagcaat gattaactca
    17221 ttattaattt tttttaaaaa agattcatcg ttgtatatct caatagtgaa aggttttatg
    17281 ctacttaaat ctccaccaac ctcttgaata gccttaacaa tttctgactg aagagccaat
    17341 aaaacttttt tacttattgt tccatcaatg acttcatttt tttcattacg tttaggaaca
    17401 tctctacatt caataacaaa agcactagta ggagtatgtt ctacattgga cgtaccaatt
    17461 agtagatttt tcaagcttgg tgagttaaaa ctcacttttc caaaattatt ttccatttgt
    17521 tacctcttta tctttgtgtg cacactagat taatttcatc aagcagttca tgacctcctt
    17581 gacagtcata ttgtctcatt tttaattagt tgaaatgtgg ggataaaaat tttttgacaa
    17641 caaaaaaatc cccacgcgaa gtggggaaaa tatgctatac agtactaaat aaaaatttta
    17701 ttatttacga taaattaaac tttcgagtgt tagtttatct atcattggta ataaaatata
    17761 ctttgctaat aagtctaact tttctggaag tttttgatag ctaagataag attccttatt
    17821 tttaggtgat agtgtgacag agtccttttt cctaaataaa aatactgaat cgttttctaa
    17881 aatttctata gtatcaaact gattataggt aaaatcaata aatttatctt ttaattcatt
    17941 gtaagaagaa cttgccaaag gaaaatgttg ttgaaagtat tctttgatat ctcctgtatt
    18001 tgttagtgat aaattcaata agtgcttaga atattctggt attccttgaa tatcaagaat
    18061 catttcaata aagaaatctt ctaaatattc gtctatatca cggccccata atacttcatt
    18121 ctcatcatta aaataatgtt cttcattaac aaagtaattc aatacacttg gagttattaa
    18181 atagggattg ttcctactta aatcagataa attggagtaa tttaatattt tcccaataag
    18241 tttttcatct gaatgtaaat cgatatgtct tttgagtttt aaatctttgt atttcttttg
    18301 gattctttgt gaacattttt taaaaataaa atgacatgaa ttaggaaatt tttgcttaca
    18361 taaattattg aattgcttac ttgacatata tttaaacttc ttctatatca tctggaatat
    18421 aagtaattac atcatataca ttgcagttca aaataaaaca tagggtatct aatgtagctg
    18481 tagttattgg ttttcctttt ttcattctat gtagtgtatt gctggataga ccgtggtgaa
    18541 aaattaattc gtactctgtt tttccttgtt taaacaaggt ttcgtagaag ggtttatatg
    18601 aaatcatcgt tctcatctct tttctaaata gataatttca ttttatctct attaatttgt
    18661 tgactatact caataaattg actataatta gagggagagt aattgattgg aggattttat
    18721 attgaaactt gaagattttc agacttttcc atttaaaagt gtccaagaat atatttcaga
    18781 caaagaaaaa gcaataaaat tcagtttctt attgcaagga gacgaacctg accgttctga
    18841 attgatgaaa ttaatatata aagacatttt cgaatggtat gatgacaaag tacatagtgg
    18901 cgacactctt ataacatatc gtacagcaat ttttcgaaaa tattatggaa aatcatatag
    18961 taagttatcc agagataagc aacgcgagat tcttaatatt ataaaatcat acactgaata
    19021 tgatgatgat tttcctttcg aatttgagct tgacaataaa gaaaaaaacg tttatcagat
    19081 ttgtaataat tatcaaatag gaaattttgg aatttttcca aaaggaagaa taaatcctaa
    19141 aagagcacag tctccttata atgattattt tgaccttact ctatcagtaa tatgggactt
    19201 atatgatggc acattgactc cagatgatga gtttaaaaga gcaattttag atgaaaagga
    19261 atattttgac caatttaaag attttgaaac atttctatcc gataacttct taactgtatt
    19321 ttttgatgat gaaggatatt taattcgatt atctgaaatt gatgattttg aggaatatgt
    19381 aagaattagt aatcaaatta tttatactag agggcttgct attctaacct accttcaatc
    19441 aatgtatgat gataatagtg aattgcctac ccaacaactt gaagaaaaga aaacagttcc
    19501 tagaccaact accaaagagt tagcacatcg aactcttaaa attgcagaag aagaaataga
    19561 taaaatttct aaatttgatg aatattataa tgaacttgaa tttaatcttc ataaagaaaa
    19621 atttgaaact acaaaaaaac gaatatacgg tgctattgtt cttttcttgt tcattgtatc
    19681 actatttttt tacacttcag aaattatcat gttcatttgg attttatcta cagtactata
    19741 tgtagcagat aaaatcagaa ttgttaaaga aaaaataaaa tacgataaaa taataaatgc
    19801 gactcaagaa aaatataggg aagaaaagaa aaaattatta tctactttgc gaaaagagta
    19861 ctactccatt ccaactgaat ttagaacata taatcatatt tcaggtatac aatatttttt
    19921 aaacgctgat attgcatcaa atttgcaaca agctattcac tattattcaa atgaatacaa
    19981 ttctaaaaga atgcaagacc aaatttatag cttacatcat tcaaacacaa tattacaaga
    20041 tagaattaag gagctcgaat tagaaagaga gctggaaaaa tactaatcaa aaaggagaat
    20101 actacaatga caaaatttaa tttacaatca aatcaaattt atagtgaatt aagtaagttt
    20161 gagatagaag aaatactgta taatgctaca aaacaattga acggtagtgt tgaacggcaa
    20221 agttctgaag aaatttcata ctctggacag ggaaattttt ttgattacat gaagcaccca
    20281 ggtttaagta gatatacatg ttggcaagtc ttagttacta tatcagattt aggggataaa
    20341 cgaaaagttg agctaactgc agtcggagaa agtccgatta gttacctact aaataatttt
    20401 ctatcattca ttacttttta taccttattc caacgtcatc gtaatcttaa ttttggcata
    20461 tcaaaagaaa aggctaaata cctttctaat ttgttgtaga agataattta tatacaaaaa
    20521 actctcttag tacatattca cactaagaga gttttttgta atctatttgc caagtttggc
    20581 gggaaaattg gcggggtaac ttttctaaaa agataaattt ataccattct aacttctata
    20641 aacccgatag aatcggtgta aaacattcat ttttactttc tatattattc ccactcaact
    20701 gttgcaggtg gtttacttgt aatatcgtag acgatacggt taacatgatc cacttcattt
    20761 acgatacgta cagagatttt ttgaaggact tcccaaggaa ttttggcaaa gtcagctgtc
    20821 ataccatcga tagaagtgat agcacggatt gcaatcgtgt agtcatacgt acgaccgtca
    20881 cccataacac caactgaacg aacgcctgtg ttaacagtga agtattgcca gatatcacgg
    20941 tcaagacctg ctttagcaat ttcttcacga agaatagcat ctgactcacg aactgtttca
    21001 agtttttctt cagttatttc acccatgaca cggatcgcaa gacctggtcc tgggaatggt
    21061 tggcgccata cgatatggtc tggcatacca agctctgtac caaggacacg aacttcgtct
    21121 ttataaagag tattgagtgg ttcaatcaat tcaaactgca tgtcttctgg aagaccaccc
    21181 acgttgtggt gtgacttgat agtttgagct gtatccgtac cagactcgat cacgtcggta
    21241 tataaggtac cttgagcaag gaatttcaca tctttgagct tgcttgcttc gtcatcaaat
    21301 acatagacaa actcgttacc gataatttta cgtttttgtt cagggtcaga aacacctgca
    21361 agtttatcaa ggaaacgctt agctgcatct gctttgacga tattcaaacc aaacttacca
    21421 ccaagcatgt ccataacttg gtctgcttcc cctttacgaa gaagaccgtg gtcaacgaag
    21481 atacagatta attgatctcc aattgctttt tggagaagaa ctccaacaac tgaggagtca
    21541 acaccgcctg atagaccaag aaggacacgt ttatcaccga cggtttcacg aattttttgg
    21601 atctgcatat cgatgaagtt atccattgac cagtcgcctt tagctttaca gatgttaagg
    21661 gcaaagttac gaagaatatc atttccgtat acagaatgac gaacttctgg atggaattgg
    21721 ataccgtaaa tatgtttatc agggttttca atggctgcgt atgggcagtc agcggatgta
    21781 cctgtacgaa caaagtcaga aggaatttca gtaactgcat caccatggct catcaataca
    21841 gtttgttcat caggtgttga ttcaaaaaga gctgatggtg tatgtgttag ggttgattga
    21901 ccgtattcac gatttccagc atcacctgca ggaacaactt ttcctccaag cttatgggtc
    21961 aataactgca taccgtaaca aattcccaaa ataggaattc cgagttcgaa gatttctggg
    22021 tcaatatcaa atgaaccatc ttcatataca gaatttggac cacctgaaag gatgattcct
    22081 acaggattga tttcacgaac ttcagcagct gaaattttat ggctttttag ttctgaaaaa
    22141 acaccaatct cacggatacg gcgtgaaatc agctggttgt actggctacc atagtccaat
    22201 acgatgattt tttctacatc ttgcaaatca gttgaaatgt tgctcatctt tttcctttct
    22261 caaaagaaat atcttttctc aatattctat cacaaataag ggcgaattac caactaaaca
    22321 aggcgaagtt tgactttttc tagtttattg gggtacaata gagaaaagat agaaatgaag
    22381 tgaaaaatat gctacctgct tatatgaaaa tccatgatca gataaaaaag gatattgacg
    22441 agcaccgttg ggctattggt gagaggcttc ccagtgaaag agatttagct gagcagtttg
    22501 cggtcagtcg catgaccctc cgccaagccg tatctctatt agtcgaagaa ggcgtcttag
    22561 agcgccgtgt aggaagcggc acctttgttt ccagtactcg agtacaagaa aagatgcgag
    22621 ggacaaccag ttttactgaa attgtcaaat cccaaggtaa agttccctct agccagctca
    22681 tttcctacaa aaaaaccatt cccaatgagc aagaagttgc caagctagga atttttccaa
    22741 cggacaatat tatccgaatg gagcgggtcc gctatgccga ccaagttccc ctagtttatg
    22801 aagttgcttc tattcctgaa aaattcatta aggactttaa aaaagaagaa atcaccagtc
    22861 atttcttcca aaccttgcaa aaacatggct atcgtatcgg caaatctcaa cagaccatct
    22921 atgctcgcct tgctaaagaa aagattgccc actatttgga agttgaaaaa ggacatgcta
    22981 ttcttggatt gactcaggtt tcctacctag aagatggtac tgcttttgaa tacgtaaaaa
    23041 gtcaatatgt aggcgaacgc tttgaatttt atcttgaaaa taattagatt accacgcaaa
    23101 aactctctgt cacggacaaa gagtcttttt tatttttcta agaataaatc tttcaaagga
    23161 atcaaagtta cagcaaacaa tatcattgcc ataccaagaa aatcaatggg ataaaattgt
    23221 tcattcatta ttaagaaggc aaagaaaacc gccgatattg gctcaattga agccaacaag
    23281 cttgacttga ccggtcctat cagactggct cctttaagga aagctgtata ggcaaagaca
    23341 gtcccgataa ggataatgcc tgcaaacgca aggagaaaat caagactagt tgggatatcg
    23401 gcctgtagaa cccctgtaaa aggaagggcg accaaacctg ctatgaccat tcccacacca
    23461 atgaccaagc tgctccccca ctttttaatc aaggctatgg gtaaaatgat atacagagca
    23521 taagtcaagg cagaaaagag accccagaac aggccagcag gtgtcatgga taactggtcc
    23581 aactgcccat gtgttgcgat caggaaggtt cctccgatgg cgaatatgat ggaaactatc
    23641 tctcccagtg tcggtgccac cctatccttg atacagctat aaattaaaat tccgacagga
    23701 caaacatact gaagcaccgt cgctgttccc gcattggtct cctgaatagc agacagatag
    23761 gcgaattggt tgagaaaaag accaatcaga gcaaaaataa gaagagacag caaactcttt
    23821 ctatccttta aaaagaccag tattttatcc tttgcagtag cataagccaa gatcatgaga
    23881 attccaccag cgattaaaag acgcaagttg gtcaagacca gagccgaaat tccgtgtgcc
    23941 attaggtatt ggccactcgt tcctgacaac ccccaagcaa taccagccac aactgttagt
    24001 aaagtccctt ttaaactatt tgacatgtct ctccttactc ttctttacga atcaagttca
    24061 tcacttgatt gcggtctaat atccattgag ctctctcgtc cttttcatag gtacgattcg
    24121 ataggaaaat agtggcttct tgcttctgac gattccacat gataaaggta cctgtatagc
    24181 ccgtatggtc tagccaatct ccttccaaat tccatgctaa agaacgttcc ttgtcatcca
    24241 aaggagaaaa attttgattt aagtctcttg caaaatcatc tgctaaatag tgttctaaaa
    24301 agatttgtaa atcctttata gtcgaaaata aaccagcact cccagcatgt ctacccagga
    24361 gacgagcctt gggatcatgc actatgcctg cctctacacc tctaactgtt ggaacagcaa
    24421 gctcaactgg cccaaccttg gtttccgtca ttccccaagg tttccagact tgatccttta
    24481 aaatcacatc caaatcttga ttaaaaattc tttccaaaat aaagcccaac agcaaaaaat
    24541 ggacatccga ataaagaaag gctggctgac ttcgtctatt gagatgaaac atcgcttcct
    24601 ttaattcagg ggctgttaaa agatcacgat taggaataaa aggatcaagg tctgttgcat
    24661 gagtcaagag ctggcgaata gtgatgtctg gataatcact ctcaggtaaa aaatctatta
    24721 ccagtctatc aatatctaat tgacctattt cccacaagaa ggtacaaact gtgccaaccc
    24781 caacaacctt actgacacta gctaggtcat aaactagtcc tgcctcagtc tgcaagccat
    24841 gctctgggtc actctggcct aaatagaact ctgtccattg attgtcctta aaatacgcaa
    24901 aagaggctcc gggataaatt cctgcctcga tttgttcttc tattttttta ataatcttgg
    24961 tccacttcat acttcttcaa accacaattc aacattattt ctatctttac aaaggaagaa
    25021 tttttcagac ttaggaataa aatattcagt agactcaaac ttctggcgaa gacttgctat
    25081 gtctaattca ttgaccaaga acttgagcat agataagtcc caggtaaccg tattgtccac
    25141 agtcaaatcc tgcccctgag ctggaataaa atcaagggat gccccaattt cagatgattc
    25201 caagaaactt tcgatatcag ttgggagatg taattccata gaaatctcaa atttacttaa
    25261 agaaattgat accaaatctg tttgaaattc aggcttttct cctacttcta ctagacttgc
    25321 tctgtcatct tccgcatgaa tcaaaatcaa atcatcttct ggtgagaaaa tttcaaaagc
    25381 gtagccattt tgacctttat ataatcgatg aatcgaatct gttttagata agattccttc
    25441 aatttctaag ggattttcca ccttgacaat caatctagct agtttttttc ttccctctac
    25501 cttacgagta cgcatactgg gagcttcttc taaaaccagc ttttcaagac ccgtttggtc
    25561 acctagtgac agaaaggccg attcttctaa caaggccttc attccaaggg tttcaatata
    25621 aaatgtttca tttaattttc tattattagc ttttaaagta ggaataatcc gtacaatctg
    25681 atttacattc ataaattcct ccgtcacttt ttattttaaa ggattttaga attttttaca
    25741 agatattatg ctcaaattta acattattta gctatttagt aaagatagtc tttcaaggct
    25801 tttgacaaag cctgataacc agcaatactg aggtgcagtc catcagttgt atattctttt
    25861 ttgagttggc ctgcttggtc tgtcaaacaa tcaaatactg gcacaaattc cacctgcata
    25921 taggcagatg caagctcttg ataggcttga ttccagttct gaattttttc attcgagcgg
    25981 atatagactg cctgctggta ctcctctctc tcattgacag gcaaaatgga aagcaattta
    26041 atctctgtca atggataatc gcgagcaacg gattgaatga tagcttcgag attattgaga
    26101 gcctcattca caggaacatc ctttccgata tcatttgtcc caatcagaag aaaaatttta
    26161 tctactgctc caccatatag atgagcatca aggttctcta gtaacagtcc tgtctgatag
    26221 ccacgaattc ctcgattgac aatcgtcttt gaagtcccaa atagctcctg tagaggataa
    26281 tactcgacaa tggaatcccc aataaaaaga atgtttggtt ctacaacaga aatgtgattt
    26341 aggtgacgat acttagtttg aattttttct tgttccttta ggagccaatt ttctaataac
    26401 tgtactgcca cttcattctc ctttttctaa ccagttttcc aaaacttgat aaactcctcc
    26461 ttggctgttg gctggtgcta gagcagtcgc cacagctttg gctttctcat cagcattttc
    26521 catcgcatag gcaattccag ccatttcaag catttcaaca tcattttcac tatcaccaaa
    26581 agccatgatt tcttgggatt tcaagtccca gcgcttgagt aattcctcca agccccatgc
    26641 tttatgaatc ccagcttgga ggatatcaat gcaaccatag ccactggata cagctcggac
    26701 acggccatca aagagagcat tgatttcttc caaaaccgaa ctcaaacgtt cctcaccaac
    26761 aaccatgctc atcttgagca caccaccaaa gaggtcagat gttaattcat ccacaaattg
    26821 catccgttgg tagaattttt caatcatttc tggagtcata aaactttcaa gatctgtaaa
    26881 aatcgtacct tccttgacaa aatcaccctt catccccgtt acaacaaact ggtcctgaca
    26941 cgctcgaccc ttgaaatgag ccaaagcctt gttgacaatg gcgtcatccc atgtctgagc
    27001 ctgaatcaat tcattgtttt caaaaatacg agcgccatta gcaacaacca gaaccactcg
    27061 atccaccaag ggactcagta gttgtctcat gcggtgaatt tcattgcccg tcgcaatgac
    27121 aaaacgaatg cccctttgat ccaactgatc taaaatcttt tccaatcgtg ggagatcaag
    27181 ctgaccccta gcatccagca aggtcccatc catatctgtc gcaattacct taatcatcat
    27241 ttactttcct ctggattcaa gctaatacca cttcaatccc acatgttcat tcatttcttt
    27301 ataggctgta tcaattcgtt ccttagtcgc ttcatctaac tggtcacgat gactgccacc
    27361 cctctataaa atcttccaaa atataagttt ggtaatgata caagggatat ccttctggtg
    27421 aaaaggttcc ctttggtgtt cgattgaccc aagtaggatg agctttagct gttccgatag
    27481 ttgtttttcc atccttcttc ttgatggtga catccatgag aacaccacgt tcagtccact
    27541 tagcattctc ttcatctccc atagattcaa ttcgttgatt ggaaatgaag ttccccattt
    27601 aatagataat gagtttctta tctccatctt tttcaaccat ttcagatggt tcaacaacgt
    27661 gaggatgccc tccaaagata atatccgctc cccaatcgat catcttgtga taaagagctt
    27721 tttgttcttc agttggttcc aatcgatact caacacccat ctgaagcatg ataatggtga
    27781 tatctgcttc cttctctgcc cgttcaattt cagccttcat cttatcttcg tttaaatctg
    27841 aaagataacg attatagtct tccttagaaa tatactgctc aattccattg aaaccatagg
    27901 aataggctaa caatgcaacc ttgataccat tcacttcctt aatgaccagc ggagcctgaa
    27961 cacgtggttc gtgcgtataa actccgattg gagtgattcc agctttctca ataatatcgg
    28021 ccgttgaaat aactccctca atttgcgaat ccaaaatatg attatgagct aaatccagca
    28081 catgataacc tgcctcctta atagcatcca taacttcaac aggagcatta aagagaagat
    28141 aacccgctaa ataatgatcc ttattaatgg ttccttcaaa atcaccaata gctaaatctg
    28201 cttgcttgag ccaaggagtc acatactcaa aattttcatg aaagtcatag gtaccgtctt
    28261 cttttttagc tgaaaagaaa agtccatcgt ggtagagcaa atccccgtgg gccataattc
    28321 tggcagtttt ttcctcttcc tactcctgag acttttgctt agtcccctct tgagaaatag
    28381 tatctcgttt ttgactagtc aagggattcc ttggaagctt tcaaacaaca agaccaagcc
    28441 cattgataaa ccaactgcta gcaagagtat cgccacaaat cccttattgc tccacttgcg
    28501 ataactccta aaaagtttac caagcccttc ataaaacgaa aagctaaacc accctgattt
    28561 cgattttgtc ttctttgtat cttcgttctc cctactttct tatgcaagcc ttttcttttt
    28621 attatatcac agataagtat ttctttcaca attgaattga acttcctatc tattttctat
    28681 aaatcctaaa tgccataatg ctttcaattc ttgtcatttt gtgatatcat gtagaggaaa
    28741 tgaactaatc cacagtggct tattccaagt ataccacttg ggctttggca gtagctaact
    28801 gcactaaaca taatataagg agagaaaatg tctgcaatag aacgtattac aaaagctgct
    28861 cacttaattg atatgaacga tattatccgt gaagggaatc ctactctacg cacggttgct
    28921 gaggaagtca ctttccccct atctgaccag gaaatcatcc taggcgaaaa gatgatgcaa
    28981 ttccttaaac attcccaaga tcctgtcatg gctgaaaaaa tgggactccg cggtggtgtt
    29041 ggactggctg ctccccagtt agatatctca aaacgcatta tcgctgtttt ggtacctaat
    29101 attgttgaag aaggcgaaac tccacaggaa gcctacgatt tggaagccat tatgtacaat
    29161 ccaaaaatcg tctctcactc tgttcaagat gctgctcttg gcgaaggaga aggttgcctg
    29221 tctgttgacc gtaacgtgcc tggctatgtt gttcgccatg cccgcgttac tgttgactac
    29281 tttgacaaag atggagaaaa acaccgtatc aaactcaaag gctacaactc cattgttgtt
    29341 cagcatgaaa ttgaccacat taacggtatc atgttttacg atcgcatcaa tgaaaaagac
    29401 ccatttgcag ttaaagatgg tttactgatt cttgaataaa gaaaatcccg ttgcaagacg
    29461 gggttttgtg ttataataga ggcatgaaaa caaatgatat tgtctatggt gtccacgccg
    29521 ttaccgaagc cctccttgca aatacaggaa acaaactcta cctccaagaa gatctccgag
    29581 gtaagaatct tgagaaagtc aaggaactag ctacagaaaa gaaggtgtcc atttcttgga
    29641 tatcaaaaaa atctctctct gagatgactg aaggtcctgt tcatcaaggt tttgttctac
    29701 gagtgtctga atttgcctat agcgagctag attgcatcct tgcaaaaaca cgccaagaag
    29761 aaaatccact tctattgatt ctagatggtc taaccgatcc ccataatctg ggttctatct
    29821 tgcgaacagc cgatgcgacc aatgtttcag gtgtcatcat tcccaagcac cgtgctgtcg
    29881 gagtaactcc tgtcgttgcc aaaacagcca caggtgctat tgaacacgtt ccaattgccc
    29941 gagtgaccaa cctcagtcaa accttagata aactcaagga tgaaggcttc tggacctttg
    30001 gaacggatat gaacggtact ccttgccaca agtggaatac aaaagggaaa atcgccctca
    30061 tcattggaaa tgaaggaaaa ggtatctcta gcaacataaa aaaacaggtc gatgagatga
    30121 ttaccattcc gatgaatgga catgttcaaa gcctcaatgc cagtgttgct gcggcaattc
    30181 tcatgtacga agttttccga aatagactat aaaaaagttt ccagtcatct gattggaaac
    30241 ttttttatga ttaactatgt tctgtaatga atttataggc ttcttgacca gcgatagctc
    30301 catctccaac cgctgttgtt acttggcgaa ggtctttcaa gcgaacatct ccaactgcaa
    30361 agataccgtc gactgcagtt ttcatgtggt tatccgtcac aatccatcct gcctgatctt
    30421 ggatattcaa ttctttaaca aaatcgctaa gagggtccaa tccaacatag ataaagacac
    30481 caccgaaggc ttgttctgtc acttgacctg ttttcacatt ttcaaatacg actgattcta
    30541 ctcggttttc acccttgatt tcccttacta cagaatccca gataaagctg attttttcat
    30601 tcgcaaaggc gcgatcttgt aaaacctttt gggcacgaag ttggtcacga cggtgaacaa
    30661 tggtaacagt cttagcaaaa cgagtcaaga agagtgcttc ttcaacagct gaatctccac
    30721 caccaactac caataaatct tggtcacgga agaaagcacc atcacacaca gcacagtaag
    30781 aaacaccacg actgttcagt tcttcttctc caggcactcc caaaggacgg tgtttagaac
    30841 cagttgctac gataacggta cgtgtttcat atgtttggtc atcagtcatc actttcttaa
    30901 aatcaccatg gtcttcgaca ttttcaacat aaccataaat gtgctcaaca ccaagatttt
    30961 caagtggttc aaacatcttt tcagccaatt caggtccact aatattagcg tatcctgggt
    31021 aattttcgat atcagatgta ttattcatct gaccacctgg cagaccacct tcaatcaaag
    31081 ctacttttag attgcttcga gcagcataca aggccgcagt catccctgca ggtccagcac
    31141 cgataataat agtatcgtac atatagattc cttctttctt gttgtaacta tctttattct
    31201 aactctttct tgtcaatcac gcaaggatta tgccttgaaa acaagaatta aactcataac
    31261 cgcaaaggat aatactggga caaccaagac tccaatcata atcatatcat agagatgggc
    31321 ttggcgagcc ttggctgtct tatcaactcc cgacatggct ctcagaccaa tccaaatccc
    31381 taaaaaaatc agaacaagga tggtggtcaa gatcaaactc tcgaaatata aagaaaatag
    31441 ttgcagtagc atgatttctc tcatttctat cttttttaaa gagtaaactc agctagtcca
    31501 actaactgag ttttccttta tctattatat caaatataag tccgtttgta actagcgaag
    31561 aattcttttg tccgctcttc tttaggggtg tggataatct catccggtgt tccagactcg
    31621 atgattttcc ccttatctaa gaagagaatc ttatcagcca cttgggctac aaaggacatg
    31681 tcatgactaa ccaaaatcat ggtttgacct gacttagcag catctgcaat agacttttct
    31741 acttcaccaa ccaattctgg gtcaagggct gaagttggtt cgtctaagag caaaacatct
    31801 ggtttcatag caagcgcacg cgctagggca acccgttgct tctgtccacc tgataaatgg
    31861 cgaggataat ggttttcacg gtccgaaagc ccaaccttag ccaactcttc cttggcaatc
    31921 ttagtcgctt cttggtcaga taatttcttg acaacaacca agccttcttt cacattatca
    31981 agtgctgttc ggcgttcaaa caaattaaac tgttggaaaa ccatagacaa cttacgacgt
    32041 agggcaagga tttcttcttg agtgatttta gaaaaatcaa ctgaaaaacc atcaatctga
    32101 atagagccac tgtcaggtgt ttcaagataa ttgagactgc gaagaaaggt tgattttcca
    32161 gctcctgaag aaccaatcaa ggctacaact tccccttttt gaatatccaa gtccagatga
    32221 tccaagacag tctgtcctga aaaggatttg cttaaattcg aaatcttaat cattaacgaa
    32281 ggtctccttt cacatctgtt tgcactgtat caggtgcaga aatatccatt tttctctcga
    32341 tgaaacgacc gaggctttca attccgatat tgaccaccca ataaacaagg gcaacggaga
    32401 tgaagcgttc aaaatagcga taatcagctc cacctagaat ctgagcttgg gcaaagactt
    32461 ccacaacacc cgcactaaaa gctagagatg ttcccttggt caaaccgatg agggaattaa
    32521 tcaaggttgg agtagctacc accgctgcat taggaataat cactcgtcga taaacttgcg
    32581 ctcgggtcat acccagactg cgtgccgcct caatctcacc aggattaact gagagaatgg
    32641 ctgcacgaat ggtttcacta gcataagctg cctcattaaa ggcaaaggcg acaatcgcaa
    32701 aagctgcagc tggaatcgca ttgatattga gaccagttcc ccattgctga ttgagggctt
    32761 tcaaagccaa agggattccg tagtaggtca acatgagttg caccaaaatc ggtgtccctt
    32821 ttaagaaact aacaaagaag gcctgcaagg gatataaaat cttgacacga ttgatcttca
    32881 caatggcaaa aagaagcgcc aaaaccaagc caaaaagggc accaccaatt gtcaacataa
    32941 ttgttgttgg aagttgttgg acaattctag ggattccatc aaagaccgaa cgtaggctaa
    33001 acagcttgcc atccggaatc aattgcatca agttttggta ccaatctgat gctaaaatcg
    33061 ttgtaacatt cataaaaaca tcctcttctg ataatgattc attctaccat gcttctgccg
    33121 tcaatgaaat tatttgctac ggtcagatac agactttgtc tacctactag tttatcatac
    33181 tttgaaacag ggaagttata tattttatct atcaaagaga tagataaaaa ctatttcagt
    33241 cccagttctt cataagattt tcgataaccg atttgcttaa cagttccatt ttctactaaa
    33301 atgggccgtt ttaacaacat accgtcactt gctagcaact cagccgcttc tcggtttgac
    33361 aaacttccta ccttatcttt tagccctaat tcacggtatt tgataccact ggtgttgaaa
    33421 aattgcttca attcaaatcc tgaggtttct agccaattca aaatgacttc ttggctaggt
    33481 gtttcttcca cgatatggac ggctttatag tccacaccta attgatttaa ttcttgtttt
    33541 gcttttttac aagttgaaca tttggggtat tcgataaatt ctaacatgtg cttctccttc
    33601 tattgtttct atctttaaaa tctactcctt catgctccaa gagccaagct ttcttttcca
    33661 ctcctgcagc ataacctgtc agacgcttgc ctgctcccaa cacacgatga caaggtacta
    33721 ggatagacca aggattgcgt cccactgctc caccaattgc ttgagcagaa gccacttgca
    33781 ggtcttgagc aatttgtcca taggtcactg tctgaccata aggaatgccc tgtaaatagt
    33841 cccaaactct cttttcaaaa ttcgttccga ttggcgccaa gagcaagttg gataaatcct
    33901 gaggctcgcc tttaaagtaa tcatctaagc aagcaataac tgggtctaaa ataggatgac
    33961 taacaacttc ttctatcgtt tcatctccta gtcccctctc aaaatgcttc tgctcctgaa
    34021 cccaaattcc atacaaataa tggtcatcag ctacaagtga tagaatacca attggtgagg
    34081 agtagagtat ttttacatac ttcttttgca ttatttcttt aatttttgat aggccaagcg
    34141 ttcgccatct actggcacct taccaacttg tttaaaacca agtttttcaa aaatatgttg
    34201 cataaccttg ttttcagcat gcgtatctga gcgaaaatca agataatcaa aaccttcaat
    34261 caagccctct aagaaggttt gagcaactcc ttttccctgc acatctgctg ccacagcaat
    34321 acggtgaaag actagatact ctgactctcc agcttgccag tttccctcat aaatagcttc
    34381 ataggcctcc tctggactct tggtcacagc agcataggct agcagttctc cctcttccaa
    34441 ggctacgtag gcttgccctg agatgatatc atcgataata acatctgcat ttggatagcc
    34501 attttgccac tggtcactac cagcatctgc taaacatttt ttggcatcct ccatcacctg
    34561 catgatggca tctacttcat ttggaaaagc taaacgaatt tccatctttt ttcctcattt
    34621 ctgactagtt tctcccatca tagcataatt taagtatttc tacaagcagt taaaacttga
    34681 ctttgtgttt ttgttatttt ataatctagt tatcaaaact atataaaaag gagttgaaaa
    34741 tgaaaactac cttttcctac ccaaaatggg cagaaattcc aaacattgac ctctatctgg
    34801 accaggtttt gctctatatc aatcaggtct gcgcccctat ctctcctaat aaagacaagg
    34861 gcctaacagc atctatggtc aacaattatg tgaaaaatgg ttacctgaca aagcctgaca
    34921 aaaaaaaata ccaacgccaa cagattgccc gtttgattgc tatcacaacc ctcaagtctg
    34981 tattttctat tcaagaaata gcccagacac ttaatactct acaaactcaa gcaagttcag
    35041 accaactcta cgatgctttt gtggactaca tgaaccaagg aattgaccca gctaacccta
    35101 ttatccaaac cagctgccaa accgttaaac tctatcatca aactctagac ttaatcgatc
    35161 atactcaaga ggaggtaatc caatgaacac tagtcttaaa ctcagcaaac aactcagttt
    35221 tggagaggag attgctaata gcgtgaccca tgctgtgggt gcagtcatca tgcttatctt
    35281 gctgcctatt tcatccatct atagttatga agcacacgga tttttatcct ctatcggcgt
    35341 ttccattttc gtcatcagtc tctttctcat gttcctatca tccaccattt atcactctat
    35401 ggcctatggt tcgacccaca aatatgtttt gcgaatcatt gaccattcta tgatttacgt
    35461 tgccattgcc ggctcataca cgcccgttgt cttgaccttg atgaataact ggtttggcta
    35521 tctgattatt gtcatccaat ggggaacgac catctttggt attctctata aaatctttgc
    35581 taaaaaggtc aatgagaaat ttagccttgc tctttacctg attatgggct ggttggttct
    35641 ggctatcatt cctgccatta tcagtcaaac gacacccgtt ttctggagtc tcatgataac
    35701 tggcggactc tgttatacag ttggagctgg attttatgcc aagaaaaaac cttatttcca
    35761 catgatttgg catctcttta tcctagctgc gtccgcactc caatacatcg ctattgttta
    35821 ttacatgtaa aaaagttgag aagttcaatc tcaacttttt tctttacaca tattgataaa
    35881 gtactggtgc aagcgcacat catcagtcaa ttctggatga aaagaactta ccaacatatt
    35941 tttttcttgg gctgcaacaa tttgattgtt cactgttgct aaaatttcta caccctcacc
    36001 aacactactg ataatcggac cacggataaa ggtcattgga atcttgccaa ctcccttaca
    36061 ttctgcttcc gtgtagaaac ttcctaattg gcgcccataa gcattacgct cgaccaccat
    36121 atccatagtt cctagatgac tctctttctg agaagtgatt tccttagcca gcaaaattaa
    36181 gcccgcacag gtcccaaaca ctggtaagcc agatagaatg gcttctcgga tgggaagtag
    36241 catgttctgg tcacgtaaga gcttgcccat ggttgtagac tcaccaccag gcaaaatcaa
    36301 acccgacaag tcactctgat cttgctgaaa atcatctaga tttctgagtt ctacactctc
    36361 gacacctaat tgatctagca cttttgcatg ttctgcaaag gccccttgca aggccaatat
    36421 tccgattttc atctattttc ctcgttcagc catgagaatt tggatttcat tttcattaat
    36481 accaaccatg gcttctccta aatcttcaga gatttgagct aggatttgag gattacggaa
    36541 gttagtcaca gccttaacaa tggcactcgc tcgtttaaca ggatctcctg acttgaaaat
    36601 acctgaaccg acaaagaccc cctctgcccc taattgcatc attaacgcag catctgctgg
    36661 cgttgcaaca cctccagcag cgaaatttac aactggcaat tttccatgtt catgaacata
    36721 ttggaccaat tctacaggga cttgcaaatc cttggcagca acataaagct cgtccttacg
    36781 taagttttga atgcggcgaa tttcctgatt catcatacgc atatgacgaa cagcttggac
    36841 gatatcccct gtccctggtt ctcctttggt acgaatcatg gaagcgcctt cagcgatacg
    36901 acgcaaggct tcacccaaat ccttagcacc acagacaaaa ggaacttgga attctttctt
    36961 gtccacatgg aaacggtcat cagctggaga tagaacttca ctctcgtcga tataatcaat
    37021 ttcaatagcc tctaaaattt gagcttcaac aaaatgcccg attctgacct tagccattac
    37081 tggaatacta accgcttctt ggatttcctt aatcatcttt gggtcgctca tgcgggaaac
    37141 tcctccagct gcacgaatat cagccggaat tcgttccaag gccatcacag ctgccgcacc
    37201 agcagcttct gcgatacgag cctgttcagg attctgcaca tccataataa caccaccctt
    37261 gagcatctgt gccaagtttt tatttagttc ataacgattt tcagtcattt gttttatcct
    37321 catcatttgt attggttgct accttttcat tttaagtcag aacagaatga agcacaagat
    37381 aaaaaaacta taattgtatg gggacagatt ggctaaaaac tatctgacct taacttaagg
    37441 ccagatagct cattcatttt tatttttcag ccgtaagggc agccattgtg atgtagttgt
    37501 atggtttatt gaagtgtggc aagaagaaga ggtctgtcaa tgccaattta tcaattgtca
    37561 catgctcttg gatagcaagt gagaacatgt ggattcccat gctaattgca atatcatgtg
    37621 aaaccatttg ggcaccaaga atttcacggc tatctttgtc aaagacaatc ttaattgcta
    37681 cttcatggtt gtcatgtttc atgaattctg gtttttgaag atcgttaaag cctgtttcag
    37741 ttgcgttgta accagcagct ttcgcttttt caagagtcaa accagttgaa accatgtgaa
    37801 gaccgtagat tgagatacca tttgaacctt gaacaccgat tccttccaat tcatgtccac
    37861 aagcgttgta ggcaccaacg ataccagtgc gaacagcatt tgaagcaaga gcgatatagc
    37921 ttgtatcttt acgagcattg tcataaacag tcgcacagtc accaacagcg taaacgcctg
    37981 ggatagatgt ttcttgtttc ttgtctacaa ggaaggcacc gttgcggaag agttcgatct
    38041 taccatcagc aagggctgtg tttggacgga aaccaactgc aaggataacc atatccacgt
    38101 caaagctttc tttgtcagta atcaagcgtt caactttacc atcaccttcg attgctttaa
    38161 cagtttgacc tagagccaag cggatgttgt gatcttccaa gtttttcgcc atcatttgtg
    38221 tgaagtcttt gtcatagtaa ccgttcaaga cagtatcaac gatatcaaca aggacaactt
    38281 cttttccaag acgttcaaag gcttcagcaa gttcaacacc gatgtaacca ccaccaacaa
    38341 cggcgatacg gtcgagatgt tggctcttgt cagaaagttt attgataact tcttcagcat
    38401 tttggtacaa tttcacgaat tgtacgtttt caagagttgc tttaaattcg cggtttcctt
    38461 taacaatttc aacaccttcg attggtggca agattggtgt agaacctgta gcgaaaatca
    38521 atttctcgta tgattctttg tgttcttttc cttcaacttc tgctgtaacc actttgttat
    38581 catagtcgat tgaaagaact ggtgaattca tataaacctt agcaccttta gcttctaatt
    38641 tgtctttatc agaatagaac aagccttcag caccgtcaat ttgttcacca atccaaagag
    38701 ccattccaca tcctaggaaa gagatgttag agttttgatc aaatacaaca atttcgttct
    38761 catttccaaa attatccaac atggtattga tacatgctgt accagcgtgg ttagcaccga
    38821 ctacaacgat tttactcata aaaaatttcc tgccttcatt ctaaatttac cttactagta
    38881 taccatttac cgttagcgtt tacaaggggg gtactattat ttcagcattt tttatcaaaa
    38941 ataattcccc atttatcctg ttttcaagcc tcatgaattt tatgagcata tttcttgact
    39001 ttttccaaat tttgtttgtg aaaattctaa ctttatggta ttctaataac atgaaaataa
    39061 aatgtaaggg cttcaattta gataattatt ttatattaca acttattttc tataagagaa
    39121 aggagttggt agcttgactc ttcgttcaca ttctgaacgg ctaatgggga ctactatcac
    39181 tatttcatta gtggatgaac aagccgatat ctttctccaa aaatcctttg acttgctcaa
    39241 agagcttgaa taccgcttca acgccaatag tcaagaatct gagttgatgg aaatcaatta
    39301 tcaagcagga atatcccccg tcacggttca tccagacctg tttgagctga tttcacttgg
    39361 gttagagcat agcctagcgc tctctagcca cctcaatatc agcattggtc ccttaattca
    39421 aacctggcgt atcggttttt cagatgccaa ggtcgcccag cctcaagaaa ttgaatcggt
    39481 gctgcctcta atcaatcctc atggtatcga gttagattct tctacttcta ctgtgttttt
    39541 aaaacagaaa ggaatgaaga tcgatctagg ttgtttagcc aaaggataca gtgcggataa
    39601 ggttgcccaa tttcttagga aagagggggt gacttctgcc ttgatcaatc tgggagggaa
    39661 tatcctgacc attggaaaaa atcaggcaag aggggataac ccatggcaaa tcgggattca
    39721 agacccagcc aatcctaggg gaaatcattt aatgaccatc cctgttgtca ataaatctgt
    39781 cgtgacttca ggcatttatg aacgtcacct gaccgtcgat ggacaagatt accatcacat
    39841 ttttgacagt caaacaggat atcctgttga aacggaacta gcgagtctaa caatcatctc
    39901 tgataaatca gtcgatggcg aaatctggac gactcgactc tttggagaaa gacctgcttc
    39961 tatcctctgg caagtcgaaa gtttggaggg catcgaagtc atcctcatcg ataaagaagg
    40021 ccacctaagc tgttcttcag gaattcctac tctatagaga caactgtttc aatggaattt
    40081 taaaattgta ttatgtaaaa agagaaagga aatctcatgt taaaacttat tgctattgtt
    40141 ggaacaaatt caaaacgttc tacaaaccgt caattgcttc aatacatgca aaaacacttt
    40201 gctgacaaag ctgaaattga acttgttgaa atcaaggcca ttcctgtctt caacaaacca
    40261 gctgacaagc aagtacctgc tgaaatattg gaaattgctg ctaaaatcga agaggcagat
    40321 ggcgttatta tcggtactcc tgagtatgat cactctattc cagctgtttt gatgagcgct
    40381 cttgcttggt tgtcttatgg tatttaccca cttttgaaca aaccaatcat gattacaggt
    40441 gcttcttacg gtacgcttgg ttcatctcgt gcccaattgc aacttcgtca aatcttgaat
    40501 gctcctgaaa tcaaggcaaa tgttcttcca gatgaattct tgctctcaca ctctcttcaa
    40561 gcatttaacc caagtggcga cttggttgac cttgatgtta tcaagaaatt ggatgtcatc
    40621 tttgatgact tccgtatctt tgtaaaaatc acagaaaaat tacgtaatgc acaagaattg
    40681 cttcgcaaag atgcagaaga atttaactgg gaaaatttgt aagataggag accgaaagaa
    40741 tgaaatttgt tggacttgtt ggatcaaact acgatcaatc atataaccgc aaactcttgg
    40801 aatttatccg tcgcaatttc aaattcaaat ttgaattaga agtacttgaa atcgacgaag
    40861 ttccaatgtt taaccaagac gaaaaatggg acgaaagctt ccaattgcgt ttcttgtata
    40921 acaagattac acgtgctgat ggtgtcatta tcgccactcc tgagcacaac cacactatct
    40981 cagcttcact caaatctgta cttgaatggc tttcatacga agttcatcca tttgaaaaca
    41041 agcctgttat gattgtgggt gcatcatact atgaccaagg aacatcacgt gctcaagttc
    41101 accttcgtaa aatccttgat gctccaggtg ttaatgccta cacgcttcca ggtaacgaat
    41161 tccttcttgg taaagctaag gaagcttttg ataacaacgg aaatatcacc aacgaaggca
    41221 ctgttaaatt ccttgaaact tgcttagata actttgttaa atacgtagga gtcgtttcga
    41281 aattgaaaaa accaaaacca atcgaatcag aagacttgga ttgtggaaaa ccaatcgcta
    41341 caaccatcac agaagttgac cctgacgatc cagaatgggt agaaaaagtt gcagcaatca
    41401 ctggtgctgt ttctggtgat acctatgtca aattggacca cggtatccta acagttaacc
    41461 aaattgatat gttcttgaaa gctatgccat ttgaattgac atacgctgac gacaacaacc
    41521 aattcctcta ctacaacaac gctcaccaag atccagacac tatgttcgct aaacgtgtac
    41581 cacctcaatc aggtagccgt atgtcgactg ttcatggttc tcttccacca gcacgtatga
    41641 agaacgtaga gtgggttatc ggaacacttc gcaacggaaa ccaagaatac gtccgtacga
    41701 tcgttccagg ttctcctgca ggtgttatca acactcacaa ctaccaagca atgtactatc
    41761 ctgatggatc atacgctggt atcaatgaaa tcgtctttaa cttccaacca tggcttgact
    41821 ggtacctaaa agagactggt caacgtttgg tgggtggtag cggaccattt gctcctgctg
    41881 ccggaggtca tggagacgcc gatgctactt ctggcgcttc tgattcaggg gatgctggag
    41941 gccacggtgg tgacgcagac gctacagccg gtgcaagtta ctaatgatag tttttaggaa
    42001 ccattatggt tcctttttta gcgaaaaaag actagcaaac acaaactgct agtctctttg
    42061 ttatcgtttc atctatcttt gttaaaagaa agaatacata ttatgaattt gggtcatcaa
    42121 gactacggcc atgtaatcct ttttcacgtt gtacttggcg tagtttttct ggtgtaacat
    42181 cgtttccttc ttcgtccaca attttgattc cttcaatgtg gtgacgaaca acgcgacgat
    42241 aaccttcgat gtactcctca cgtagtttgg cttgttccac tttttcttct ggtgttaagc
    42301 cttctgtttt tttcttttta gcaagctcat tgatacgagc aatttttttc ggatccattt
    42361 cttctcctct gtaataagat aaagtccgtt tatcaaattt tatttagtgt taatttggtt
    42421 aaaacaagca aacttagctg ctttcttggt tagttgtgac aagattgcca aacgattttg
    42481 acggacagcc tgatcttcag ccattaccat agtattttca aagaaagcat caatgactgg
    42541 gctaagcgca aagagttgtt tcaattgctg acttgcaggt cctgataaaa cgagtgtttc
    42601 tactgcttct gccaaagctt tttcttggtc attctcaaat agtgctgaat caactgtagc
    42661 aaccccttct gccttctcag ccaggttaaa ggcacgagaa agtgattcaa cagatggttt
    42721 aaaatcttct tccttgctta cttctacgag agcacttgct gcttccaaca tatctgccac
    42781 aacaaagttt gaacctgcaa gaactgcttc cttgatatct tttagagtag agcccatcat
    42841 cttatcaaca cgagccttga taaagtccat aacctctgct ttattttcat aagtcaaact
    42901 gtcaaatttc aatgcataaa ggctatcaat cagctcatcc atagcaatgt gccaaccaaa
    42961 ggcatccaag atacgaacca caccttgggt cgcgcgacga agggcatacg ggtcattaga
    43021 acctgatgga atcaaaccta ctgagaagaa actcaaaatc gtatccaatt tatctgcaat
    43081 agcaagcact gcaccaacct tgctctctgg aagttctcct tcagctgatg taggcatgta
    43141 gtgttcacga atagcagctg ctaccgctgg agtttcacca gcaagaaggg catatttttc
    43201 acccataatt ccttggagtt cgtcaaattc accaaccata cctgtcaaca agtcaaactt
    43261 gtaaatggct gctgcacgag caaggtcaac tgtttcatcc actgacaaac cagctttttc
    43321 tgccaaaagt acagtgattt gacccgtacg aatcatgtgt tcacgaaggg aaccaatctt
    43381 ctcatggaag gtgacattgt ttaatttttc aacaagatct gaaatcacca atttttggtc
    43441 ttcacgccag aagaattctc cgtcttccaa gcgggctacc aagacttttt catttccttt
    43501 gatgacattt ttcaaacgct ctgcgtttcc gttacgaaca gaaatgaagt ttggcaagag
    43561 ttttccatct tgatcacgaa caacaaagta acgctggtgt tccttcatag aagtcaccaa
    43621 gacttcttct ggaacttcaa ggtatttagc atcaaaactt cccatgaagg cagttgggta
    43681 ttcaaccaaa ttcaagactt cattcagcaa atccgcatca atttcgatac gtacaccatg
    43741 ttttgcctca attttcttga tttggtcaac aatcatttgc tcacgttcac atggatctgc
    43801 gattacaaac tgcttacgaa ggtcttcttc atagctcaag gctgactgaa ttttagtttc
    43861 tttccccaag aaacgatggc cacggctcac acgacctccc ttgatatcaa ggaaatccaa
    43921 gtcaaactct tgctcatcca agagaacagt taaagtgtga acagggcgga tgtattcaaa
    43981 gctatttcca gcccagtgca tgctgacagg gaaagtcaat gacttcaaga catctacaac
    44041 accaggaaca atggcctcaa ctgcttgacc aacttcttcc ttagtgacat agacatattc
    44101 ttcacccttg atttcacgga attcgatatc ttcaacagtc aagccttttc cacggacaaa
    44161 tccttgagct gctttggtga agtttccatc actatccaag gcaattttct ttgctggtcc
    44221 cttgaaatct tctgtcaaat cagactgttt gtctgataaa ccagtcacac gaacagccaa
    44281 acgacgtggt gttgagaagg tttgaatggc ttcaaaagac aggcggtttt ccttgaggaa
    44341 ggctgccatt ttttcgccta gttgtttttc acttggtgtg acaacatagg ctggtaattc
    44401 ttcaagaccg agttctacta ataagttttt tgtcatgttt tctcctttac attttcttca
    44461 atcttttttg atatgcacct taggtactgg ggacgtcgct aactaactct gtgagtctgt
    44521 atggaaatcc aatgctaaat ttatcaagat ttccaacaat ctcatcaaag tggatttagc
    44581 tgactgattt ttgaacctaa ggtttcaaaa atccccacat aacagtacgg cggtgcatat
    44641 ccctctagca agtcttcgac ttgcctctaa cgattttaga gtacagtatt actcactatt
    44701 ctgcgtcttc tgctaaaagt ttaactcgtg tttcttcatc caaaagtggg taacctaggc
    44761 gtttgcgttc tgcaacaaag gttttggcta caacacgggc caagttacgg atacgagcga
    44821 tatagcctgc acgctctgtt acagatacgg caccacgcgc gtcaagcaga ttaaaggtat
    44881 gtgaacattt gagaacatag tcataggcag ggtgtaccaa gccttcttct aatgcacgac
    44941 cagcttcttt ttcaaactta tcaaagtttt caagcaacat ttcttggtcc gaaatttcaa
    45001 atgaatattt tgagtgctca tactcaggct ggataaagat ttctccgtat tttacaccat
    45061 cagcccactc gatatcatag acagagtcta cttcttgaat gtaagaagcc aagcgctcca
    45121 aaccataggt aacttccgca gtcacagggc cagttgccaa tccaccgact tgttggaaat
    45181 aagtgaactg agtgatttcc attccgtcaa gccaaacttc ccaaccaaga ccagctgaac
    45241 cagttgatgg gttttcccag ttgtcctcaa caaaacgaat atcgtgctcc aaaggattga
    45301 ttcccaattt ttccaaagac tcaaggtaaa gttcttggat atttgatgga gaaggcttca
    45361 tgaccacctg gaattggtgg tgttggtaga gacggttagg gttttcccca taacgaccgt
    45421 cagcaggacg acgtgatggc tctacataag ctgcattcca tggctcaggt ccgatagcac
    45481 gaaggaaagt gtaaggactc attgttcccg cacctttttc attatcataa gcctgcataa
    45541 gcatacaaca ttggtcattc caaaattgtt gcaaagtaag gatgatttcc tggaaagtca
    45601 atttcttaga cattgtttac tcctttttat ataaattact tgcgacatga gtctgcctcg
    45661 tcgattatac gaggcaagac gagttagtac tgcgtctagc tcaggcactc tagtgctgag
    45721 cgtggggcag tccgactgta aggaggtttc tgccactgat gcagtgaaat gttaatttct
    45781 tagacattgc ttactccttt agtttttata tttctttttc aattaatttc tgctgaacaa
    45841 accaatttaa caagggaaga gttttatctg tatttgccca tagatgataa gaatctaaga
    45901 ccgcttgtac actacctaaa ttttctacca acttatctac tgtcaaaaag ctgcgccagt
    45961 attcataaaa aatacttgca tagttcttat cataagtcga agaaccaaaa tcattcaatg
    46021 aatgccaacc atacttcttc tgaaaaagtt ctactagaga ttgattacaa attttttccg
    46081 cttgaaattc ctcttctgtc aagaaatact tgcgactaat atattcaacc atcccctctt
    46141 cgaaccagat ataagagtca gaaccatcaa aatcatctaa aaaatgctcc gaccaatgag
    46201 ctaactcatg tcctacaata tgtaagagga aattttcaga taaagaatga tagtgacttt
    46261 ctattgcttg agtttgctca gaacactcgt agtccatcaa ctgatacaaa tacaactctt
    46321 tccaaacagc taaatcaggc gtcataacca ctcgtctatt atttgtatag gttggaacag
    46381 cactttccct aataatctgt gtagcagcat taaaatctga ccaaataacg ggttgcggta
    46441 aatcacagac tgcaagttca ttctttaaaa aagattgata atctttcaac ttttcagtat
    46501 ttcttactac aaaatcacga aatgtagcta gttgactatc gtcttttaca agataaaggt
    46561 tgtccacggc tctcctttct ttcacacaat agactgaata agcaaaagaa ccacatctga
    46621 caatcctagg ttgatttaac ctaggggcgt cagaaacgcg gttccaccct aatttattac
    46681 ttcattgttt ttgaaaatac tacagaaagc gccagctcat tattttgccc tacttggctc
    46741 ccactgtccc aagctcgctt gaagaacgcc ataagacttt ctttcctgct gactattata
    46801 tcaaaaatta gaataatgta caattctttt tatgattttc tagaaatcca catcatcaac
    46861 tcgtggagcc cccgactgaa cagcagtcgt ttttaaggtt tctctctcct catgactcag
    46921 ttcaattcca aaacaatcaa gattagcttg aatacgagag gttgtgacag attttggaag
    46981 tggtaaaaat ccttctgcca agctccaggc caaggctatc tgagcaaccg attttccgtg
    47041 atttgctgct atttcttgga cttgcttgct atcaaacagt tctccttgtc caaaaggccc
    47101 ccaagcttcc aataaaattc ccttttcacg acagtaagct acgacttcct cttgatacac
    47161 acctggcgcc aagcgaactt gattgaccgc aggaacgata gttgcagttt caagcaaggc
    47221 atccaaatga tggggaagaa aattgctaac gccgatagca cggattttcc cttcttgata
    47281 gaggtcttcc atcgctctcc aaacttccgc attgcgagtt ttccatgcgt cattttctct
    47341 gagcggtttt gggttcggcc aatgaatcaa atacaaatcc aaataatcca agcccagttt
    47401 ttctatagat ttttccaaag cttgacgagt ttgctcatag gtttgctgac tattccaaag
    47461 cttggtagtt acgaacattt cttcacgtgg aactccgcta tctttgattg cttgaccaac
    47521 actttcttca ttctgataaa tcgccgccgt atcaatatga cgataaccag ccttcaaggc
    47581 ttctaacact gcacgatagg cttcttctcc atccttagcc ttaaaagttc caaatcccaa
    47641 tactggaatt tctactccat tatttaattg ataggtattc atatgcttct ccttctattt
    47701 tctttatcat ttatagcata atttttttgc taattagtac tatcttctgt aaaaaataag
    47761 tctatcacat atctgacaga cctatttttt cttgcttatt catcacgact atagtacagc
    47821 tcatgagctt ttaggcgagt attgagcatc tctggtatgg tcacaaaggt ataaccttga
    47881 tttttcaaat actcaatgac ccttggcaag gcattgactg tcggactgtg aatatcatgc
    47941 atcaaaacga tagatccgtt agctacttga tgctgaattt ctgtcaaaat agatgcttca
    48001 tttttactct tccagtccag actatccaca tcccacatga taaagctcaa atccaagcta
    48061 ttgcgaatat catctgtaat agcaccataa ggtggacgca tgagtttaga actagaaccc
    48121 agcactttag ttagcacatc ctcagtatca gtaatctgct ttttagcttc atcaagagag
    48181 agttgcgaga gaatcggatg gctccaacta tggtttccaa caacatgacc ttcagatttt
    48241 atcctcttca ccaagtcctc attcccagaa acatttttcc caagcacaaa gaaagtcgct
    48301 ttaataccat atttagctag ggtctctaat acctgcgggg tcgttgctgg atttggacca
    48361 tcatcaaagg ttagagcgac aactttttga tatttcttat caaagtaaga ttggtacaag
    48421 gccgcatctt tttcgagtaa gtacgaagat tggataacat caaagaaagc agatactggc
    48481 aaggctatct cttctaaatt ttcaaccaca ggacttggat aaaggataat ctgactatcc
    48541 ttgtaatcaa aattccatgc agacaagtct tggtcagaga agttttttac aatctgctca
    48601 ctctggtctt gctctatttt tttatcctct atgaaggagg tcaactcttt tatcagctgt
    48661 tccttagcct tactagcatc tgaaaacagt tggtcaagtg taaaaggttg cccatcttct
    48721 gttaagtgaa cctttcctag actggtcttt tcagtctctt caaccttaaa agcaactaaa
    48781 tcatagattt gtttggtcac attacgatta acgactccct ttaaacctga ctcttcttgc
    48841 tctgtatagt agaaaacaag attgtcctta ctttctagct tgtccttaac atcttgattt
    48901 atcaactccc taacagagga aatcactttc tccccttgga gaggataata ggcaatcact
    48961 tcggcttgcc cctgacgaaa atgctccttc tgatttccct cactcaattg atcatctttc
    49021 tcttttttga gcgattcaat cttttgctca aaactttttt gctggtagat cttaaaagca
    49081 ataaatccgc ctaataggca aatagaaatt gctaaaatac caatcaaagc caataataca
    49141 tgtctcgttt tcccgtgtct gccacgtcct agtctacttt tattcatatt tatatcataa
    49201 caaatttgag caataatttc aatgatacaa tttggcaatc cacaattcct ctagcaagcc
    49261 aaagcatctt acatcaactc caacatccgt atctgtagag attatgtagt tttctatcta
    49321 tggaatttct agtagattga agctagaata gtagacctat acttctaaaa cattgttaga
    49381 aatcgatttg attgtcctga tcgatttgtc ctgttctcat ttcattttac tataaaacta
    49441 tgaaaagcta ggtcatctga gaagtaatta ctatcgacaa ttgcgatagc gtatactggt
    49501 gcgatttgtt tgtagctctg gtgggtatca ccttcacgtt ggcgaatttt ttctaggttt
    49561 tgattaacct gactgcgcag ataagcccat aggcgattga tgaaaaaatt ctgatgatga
    49621 acctgaattt cgatgataac ttagattcca ttatctaact ccgccaagac gtctatacta
    49681 gtatagaaat cctgcgctga gtagggcatg gaaggcaaga cgtgaatgtt acttccctcc
    49741 aaaatcgtca cattttttgc tggcaagtcc agcatatcgc ggataaattg acaaatcatt
    49801 agttgggctg atacccggat gtctgagaat cctccttttc ctccttctat tatagcacat
    49861 ttttaaatct aggtttgcta gattctatgc ttctatctat ttattcggaa aagaaagctt
    49921 ttcttcagaa gaaagctagt agcttatttg aaattttctc ctctctgttg gatagtcccg
    49981 tctatctatg ttataatgaa agaaggattt aaaatcggaa aaggagtatt tatgctaaaa
    50041 ttaggtgtca tcggaactgg cgctatcagc catcatttca tagaagcagc ccataccagt
    50101 ggagaatacc aactggtcgc aatctattct agaaaactag aaactgcagc aacctttgct
    50161 tctcgctatc agaatatcca actattcgat caattagaag tcttcttcaa atcttctttt
    50221 gatttagtct atatcgccag tccaaactcc ttacattttg ctcaggcaaa agctgccttg
    50281 tctgctggta aacatgttat tctcgaaaag ccagctgtca ctcaaccaca agaatggttt
    50341 gatttgattc aaacagctga aaaaaataac tgttttatct ttgaagcagc tcgtaattac
    50401 cacgagaaag cctttactac tatcaaaaac tttttagcag ataagcaagt gttaggagca
    50461 gatttcaact atgccaaata ctcttccaag atgcctgact tgttggctgg acaaacacca
    50521 aatgtctttt cagaccgttt tgctggtgga gccctcatgg atttggggat ttatcccctc
    50581 tatgctgctg ttcgtctttt tgaaaaagct aatgacgcga cttaccatgc tcaacagctt
    50641 gacaatagca ttgacctaaa tggagatggt atcctcttct acccagacta tcaagttcac
    50701 atcaaggctg gaaaaaacat cacttccaat cttccttgcg agatttatac aacagatgga
    50761 accttgactc tcaacacgat tgagcatatt cgctcagcta tttttaccga ccaccaaggg
    50821 aagcaagtcc agcttcctat ccaacaggct cctcatacga tgactgagga agtcgctgca
    50881 ttttcacaca tgatccagca accagatctg aatctctacc aaacttggct ggatgatgca
    50941 ggctctgttc atgagctact atataccatg cgccagactg ctggcattag atttgaggca
    51001 gaaaaatgaa aaccaaacta ccgactgaat ggcaagaact gagtgaccaa ctcggtttcc
    51061 aagaattcac ccccattcaa actcaactat ttgagcccct tcttgctgga gaaaacctcc
    51121 taggagtgag ccaaaccgga actggtaaga ccctagcgta tctcctacca agtcttctca
    51181 gactacaaaa gaaaaaagcc caacaactct tgattctagc accaaatacg gaacttgctg
    51241 gacagatttt tgatgtatgt aaaacgtggg cagaagctat cggattgact gctcaactct
    51301 tcctttcagg ttcaagtcag aaacgacaaa ttgaacgcct taaaaagggg tcagaaattc
    51361 tgattggaac tcctggccgt atctttgaac tcattaaact taaaaaaatc aagatgatga
    51421 atgtggaaac catcatcctg gatgaatttg accaattact agatgattct cagattcact
    51481 ttgtagagaa aatcactcac tacgcacctc gtgaccacca actggtctac atgagtgcca
    51541 cgaccaagtt tgaccaagaa aagattgtgc cgaatacacg cactattgat ctctctgatc
    51601 aaaaattgaa caatatccag catttctaca tgcaggtaga ccaacgtcat cgagtggata
    51661 tgctacgaaa actggctcat gtagaggatt tccgtggtct agtcttcttc aatagcctgt
    51721 cagaccttgg gaatgccgag gaaaaactac agtatcgtga tatattggct gtttccctcg
    51781 ctagtgatgt taatgttaaa tttagaaaaa tcatcttaga aaagtttaaa gataaccaac
    51841 taaccctgct tcttgcaact gaccttttgg ctcgtggaat tgatatcgat agcctagaat
    51901 gtgtcgtaaa ctttgatatt cctagagata gcgaaaccta cacacaccgt gctggccgta
    51961 ctggtcgtat gggcaaggaa ggttatgtta tcactctcgt cactcatcca gaagaaatca
    52021 aaaaacttaa aaagtttgca agtatccgag aaattgtcct aaaaaaccaa gaactctata
    52081 tcaaataaag ccccattgct ctatacacat ccagtgtatg gagctttttt ataagcaatt
    52141 ca
//
LOCUS       DAVDZK010000011        51013 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVDZK010000011 DAVDZK010000000
VERSION     DAVDZK010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51013
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.011"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(341..1528)
                     /locus_tag="VUX16_000751"
     CDS             complement(341..1528)
                     /locus_tag="VUX16_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HET8123754.1"
                     /translation="MKKIVFASALALTLAGAVLTNDVFANDRLVATQSTDSNVLTSEV
                     LKPSSGNVLVGIKGEFLPPHQQSILDAINKIRKEAADEGLVDKYVPVKWSVDHEKTAF
                     VRAAEVSVTLKAERLSSKNNWTAFPSGNSLSGEALDLNPDGFLKAIENWHAEKANYVA
                     KKKDKTSKEFSFYYENLINPKFTYVGLAAFKNAASPQKAATVALALGTTTSSEELAGG
                     YGSAVQYTEVTASNLSTVKSKAMVVETPLKDFRKSTSDQSGWVQSNGKWYFYESGDVK
                     TGWLKTGGKWYYLNDLGVMQTGFVEVDGSVYYLSNSGAMFTGWGTDGSRWFYCDGSVA
                     MKTGWYKENGTWYYLDEEGIMKTGWFKVGQHWYYANGSGALAVSTTTPDGYRVNANGE
                     WVS"
     gene            1684..1761
                     /locus_tag="VUX16_000752"
                     /pseudo
     CDS             1684..1761
                     /locus_tag="VUX16_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(1827..2993)
                     /locus_tag="VUX16_000753"
     CDS             complement(1827..2993)
                     /locus_tag="VUX16_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET8123755.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDC
                     NLLLLQPAASNDAGFAMTSSFMSMMLTALLVFDPIEFAVKSERFEVVSSLARKVLDNA
                     EDVKELVDLDFKRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INEDTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            complement(3291..3683)
                     /locus_tag="VUX16_000754"
     CDS             complement(3291..3683)
                     /locus_tag="VUX16_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET8123756.1"
                     /translation="MTKSLILVSHGRFCEELKGSTGPQDNIYTVALLPEDGPEEFTAK
                     FEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINASLTGA
                     DADYKSRAAESIVKVNDLLADFDDDEDE"
     gene            complement(3690..4505)
                     /locus_tag="VUX16_000755"
     CDS             complement(3690..4505)
                     /locus_tag="VUX16_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET8123757.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            complement(4492..5397)
                     /locus_tag="VUX16_000756"
     CDS             complement(4492..5397)
                     /locus_tag="VUX16_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET8123758.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            complement(5425..5901)
                     /locus_tag="VUX16_000757"
     CDS             complement(5425..5901)
                     /locus_tag="VUX16_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET8123759.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            complement(5898..7685)
                     /locus_tag="VUX16_000758"
     CDS             complement(5898..7685)
                     /locus_tag="VUX16_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET8123760.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPASLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEERGVTCPLFTSDGPWRATLKAGTLIEDDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHCYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            8033..8749
                     /locus_tag="VUX16_000759"
     CDS             8033..8749
                     /locus_tag="VUX16_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET8123761.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            9066..13001
                     /gene="strH"
                     /locus_tag="VUX16_000760"
     CDS             9066..13001
                     /gene="strH"
                     /locus_tag="VUX16_000760"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET8123762.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEVS
                     STPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVNSKESNTDKTDKDKPAKKDEA
                     KAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDL
                     HLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDL
                     INYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESACTVDLGNEQAVA
                     FTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEK
                     FIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASS
                     KLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPI
                     IGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYT
                     AESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKRE
                     VEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTIT
                     ANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPG
                     HMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIF
                     NFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYED
                     KDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAYP
                     LSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRQSAEYKEEEIFELMTAFAD
                     HNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLV
                     ANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQ
                     ENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGL
                     APTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGK
                     EVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAE
                     ESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(13056..14354)
                     /gene="purB"
                     /locus_tag="VUX16_000761"
     CDS             complement(13056..14354)
                     /gene="purB"
                     /locus_tag="VUX16_000761"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET8123763.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(14417..14644)
                     /locus_tag="VUX16_000762"
     CDS             complement(14417..14644)
                     /locus_tag="VUX16_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET8123764.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            complement(14654..15745)
                     /gene="purK"
                     /locus_tag="VUX16_000763"
     CDS             complement(14654..15745)
                     /gene="purK"
                     /locus_tag="VUX16_000763"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET8123765.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            complement(15732..16220)
                     /gene="purE"
                     /locus_tag="VUX16_000764"
     CDS             complement(15732..16220)
                     /gene="purE"
                     /locus_tag="VUX16_000764"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET8123766.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            complement(16418..17680)
                     /gene="purD"
                     /locus_tag="VUX16_000765"
     CDS             complement(16418..17680)
                     /gene="purD"
                     /locus_tag="VUX16_000765"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET8123767.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            complement(17802..19349)
                     /gene="purH"
                     /locus_tag="VUX16_000766"
     CDS             complement(17802..19349)
                     /gene="purH"
                     /locus_tag="VUX16_000766"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET8123768.1"
                     /translation="MTKRVLISVSDKVGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYIKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAANKYGLTMVFT
                     GVRHFRH"
     gene            complement(19374..19883)
                     /locus_tag="VUX16_000767"
     CDS             complement(19374..19883)
                     /locus_tag="VUX16_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET8123769.1"
                     /translation="MLESKQTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            complement(19967..20512)
                     /gene="purN"
                     /locus_tag="VUX16_000768"
     CDS             complement(19967..20512)
                     /gene="purN"
                     /locus_tag="VUX16_000768"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET8123770.1"
                     /translation="MKKIAVFASDNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            complement(20509..21531)
                     /locus_tag="VUX16_000769"
     CDS             complement(20509..21531)
                     /locus_tag="VUX16_000769"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET8123771.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLVSSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            complement(21568..23010)
                     /locus_tag="VUX16_000770"
     CDS             complement(21568..23010)
                     /locus_tag="VUX16_000770"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET8123772.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            complement(23103..26828)
                     /locus_tag="VUX16_000771"
     CDS             complement(23103..26828)
                     /locus_tag="VUX16_000771"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET8123773.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNVGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVAIVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELETALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVCVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            complement(26885..27592)
                     /locus_tag="VUX16_000772"
     CDS             complement(26885..27592)
                     /locus_tag="VUX16_000772"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET8123774.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            complement(27762..29111)
                     /locus_tag="VUX16_000773"
     CDS             complement(27762..29111)
                     /locus_tag="VUX16_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET8123775.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLINQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            complement(29124..31277)
                     /locus_tag="VUX16_000774"
     CDS             complement(29124..31277)
                     /locus_tag="VUX16_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET8123776.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKEQKNGLFSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVVSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            complement(31992..32222)
                     /gene="blpU"
                     /locus_tag="VUX16_000775"
                     /pseudo
     CDS             complement(31992..32222)
                     /gene="blpU"
                     /locus_tag="VUX16_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
     gene            complement(32425..32716)
                     /locus_tag="VUX16_000776"
                     /pseudo
     CDS             complement(32425..32716)
                     /locus_tag="VUX16_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(32762..32995)
                     /locus_tag="VUX16_000777"
     CDS             complement(32762..32995)
                     /locus_tag="VUX16_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET8123777.1"
                     /translation="MKEKEIFDSIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            complement(33001..33993)
                     /gene="plsX"
                     /locus_tag="VUX16_000778"
     CDS             complement(33001..33993)
                     /gene="plsX"
                     /locus_tag="VUX16_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET8123778.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETEVVAQTAREFSGE"
     gene            complement(33990..34760)
                     /gene="recO"
                     /locus_tag="VUX16_000779"
     CDS             complement(33990..34760)
                     /gene="recO"
                     /locus_tag="VUX16_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET8123779.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(34757..35926)
                     /locus_tag="VUX16_000780"
     CDS             complement(34757..35926)
                     /locus_tag="VUX16_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET8123780.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTSQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            36075..37085
                     /locus_tag="VUX16_000781"
     CDS             36075..37085
                     /locus_tag="VUX16_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET8123781.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            complement(37198..37278)
                     /locus_tag="VUX16_000782"
                     /pseudo
     CDS             complement(37198..37278)
                     /locus_tag="VUX16_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(37313..37750)
                     /locus_tag="VUX16_000783"
     CDS             complement(37313..37750)
                     /locus_tag="VUX16_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET8123782.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(37835..40468)
                     /gene="polA"
                     /locus_tag="VUX16_000784"
     CDS             complement(37835..40468)
                     /gene="polA"
                     /locus_tag="VUX16_000784"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET8123783.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDY
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYGGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            complement(40971..41192)
                     /locus_tag="VUX16_000785"
     CDS             complement(40971..41192)
                     /locus_tag="VUX16_000785"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123784.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGIEQGREEGLEEGLKVGL
                     VNLVRQGLLTPEVASEQLGMTVAEFESLL"
     gene            complement(41185..41301)
                     /locus_tag="VUX16_000786"
     CDS             complement(41185..41301)
                     /locus_tag="VUX16_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET8123785.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            complement(41516..41869)
                     /locus_tag="VUX16_000787"
     CDS             complement(41516..41869)
                     /locus_tag="VUX16_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET8123786.1"
                     /translation="MTVRHPGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINRLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            complement(41987..42955)
                     /locus_tag="VUX16_000788"
     CDS             complement(41987..42955)
                     /locus_tag="VUX16_000788"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET8123787.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(43100..43915)
                     /locus_tag="VUX16_000789"
     CDS             complement(43100..43915)
                     /locus_tag="VUX16_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET8123788.1"
                     /translation="MKKNSILFIFILLLCIGLQYETIYYTDGSISGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKNALILSLLGGMFLSGWLSSFANTYIHDLLGGLFPD
                     SAFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGTASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKIGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(43940..44437)
                     /locus_tag="VUX16_000790"
     CDS             complement(43940..44437)
                     /locus_tag="VUX16_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET8123789.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENGPF
                     QEYLKEELGVDMSDQDFLPFQDIEESVREDMKLLIESSLIPDDVIISGAIYDVDTGSM
                     TVVEL"
     gene            complement(44510..45874)
                     /gene="radA"
                     /locus_tag="VUX16_000791"
     CDS             complement(44510..45874)
                     /gene="radA"
                     /locus_tag="VUX16_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET8123790.1"
                     /translation="MIAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEIEVAEVK
                     NARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGK
                     STLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEV
                     ERIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKE
                     GTLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLN
                     PSQVFLEERLDGATGSSIVVTMEGMRSILAEVQALVTPTMFGNAKRTTTGLDFNRASL
                     IMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVG
                     ELGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITPPKEIQVIGVTTIQEVLK
                     KVFA"
     gene            complement(45885..46400)
                     /locus_tag="VUX16_000792"
     CDS             complement(45885..46400)
                     /locus_tag="VUX16_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET8123791.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSDMGRQQVQKLSK
                     NPLLSSAEIIVSSAVARALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENRGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(46402..46845)
                     /locus_tag="VUX16_000793"
     CDS             complement(46402..46845)
                     /locus_tag="VUX16_000793"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET8123792.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(46902..46999)
                     /gene="ffs"
                     /locus_tag="VUX16_000794"
     ncRNA           complement(46902..46999)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VUX16_000794"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(47032..47499)
                     /locus_tag="VUX16_000795"
     CDS             complement(47032..47499)
                     /locus_tag="VUX16_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET8123793.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCILFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVETGILEDECAAIMQDFFRNRRKK"
     gene            complement(47700..48986)
                     /locus_tag="VUX16_000796"
     CDS             complement(47700..48986)
                     /locus_tag="VUX16_000796"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET8123794.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKEIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(49217..49453)
                     /locus_tag="VUX16_000797"
     CDS             complement(49217..49453)
                     /locus_tag="VUX16_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET8123795.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            49719..50530
                     /locus_tag="VUX16_000798"
                     /pseudo
     CDS             49719..50530
                     /locus_tag="VUX16_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(50565..50774)
                     /locus_tag="VUX16_000799"
                     /pseudo
     CDS             complement(50565..50774)
                     /locus_tag="VUX16_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(50940..51013)
                     /locus_tag="VUX16_000800"
     tRNA            complement(50940..51013)
                     /locus_tag="VUX16_000800"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(50977..50979),aa:Asn,seq:gtt)
BASE COUNT        15182 a        12141 c         9459 g        14231 t
ORIGIN      
        1 ataaatcgat agaaatttct attgaaatat acttaaaaat atactgcaat tttttataga
       61 agaatacaat gaactgcaac aatagaaaac ggaaacaaaa tctagacaaa taagtgagga
      121 gtttcaaact aattacagta ttttttaatt agattaccga ttatgctttt aatatactat
      181 aaaatattag ctcataatag aaaagtctga gattgaagcg acaaagaatc caatctttat
      241 aaaccaaaag aggtcaatgt ctgccatcaa cctctttctt atatttcatt ctttttgcta
      301 agtaagatga atactttacc tatgacttgc tcttttcagc ctagcttacc cattcaccat
      361 tagcatttac acggtaacca tctggtgttg ttgtgctaac agccaaagcg cctgaaccat
      421 ttgcatagta ccagtgttga cctactttaa accaacccgt cttcatgatc ccttcttcat
      481 caaggtaata ccatgtacca ttttccttgt accagcctgt tttcatagct actgagccat
      541 cacagtagaa ccatctgcta ccatctgttc cccagcctgt aaacatagcg cctgagttac
      601 ttagataata caccgatcca tcaacttcta caaatccagt ctgcataaca cctaggtcat
      661 tcaagtagta ccatttacca cctgttttca accagcctgt cttcacatca ccagactcat
      721 aaaaatacca cttgccatta gactgcaccc agccagactg atcagacgta gattttctga
      781 aatctttcaa cggtgtttct acaaccattg ctttactttt aactgttgaa aggtttgagg
      841 cagtcacttc tgtgtactga acagcagaac catatccacc agccaattcc tctgaagaag
      901 tcgtagttcc tagagccaaa gcaacggttg ctgccttctg aggactagct gcatttttaa
      961 aagcagcaag acccacatag gtaaatttag ggttaatcaa gttctcataa taaaatgaaa
     1021 attcttttga tgttttatct ttctttttcg ccacatagtt cgccttttca gcatgccaat
     1081 tctcaatggc ttttagaaat ccatcaggat tcaaatctag ggcttctcca cttaggctat
     1141 taccagatgg aaatgcagtc cagttgtttt tactggaaag acgttcagcc ttcaacgtaa
     1201 cggatacctc agcagcgcgt acaaaagccg ttttctcatg gtcaactgac catttgacag
     1261 gaacatactt atctaccaaa ccttcgtcag ctgcttcttt acgaatttta ttaatggcat
     1321 ctaaaataga ttgttgatga ggaggcaaaa attctccttt gattccaacc aaaacattgc
     1381 cactagaagg ttttagcacc tctgaggtca atacattact atcagtagat tgtgttgcaa
     1441 ccagtctgtc attcgcaaaa acatcatttg tcaaaactgc tcctgccaag gtcaaggcca
     1501 aggcgctagc aaatacaatt ttcttcattt ctttcttact ccttattgta gtttgaatat
     1561 tatcttaaca gatacctttt ctctcaatca aacaaaccat agaaagcgaa ttgacaatct
     1621 atggtttgcc tgatgatgta caaatcctct tgtcaagaat tcataaacac tgtcttatac
     1681 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gctgctcaaa gcactgtttt
     1741 gaggttgtag atagaactga cgaagtcagt aaccatacct acggcaaggc gacactagta
     1801 tggtttaaag agattttcga agaatattac ttttgatatt cgtggatgat aacaccttgt
     1861 accacacggt ttacggtacc tgtaggagac ggtgtatctg gtttattttc taccttgagt
     1921 gaagtcaata gagcaaagag ttgagcatat acgatgtatg ggaagacacg gtaaatatca
     1981 ttcaagacac cgccacaacc aagggccact tctttgacat tttcaagacc aaaggcttga
     2041 tcactcaaaa gcacaacacg acgagcaatc tggtcaccag caacttcacg aaccaagtct
     2101 aagtcgtact tgcgagtgta gtctgtcgtt gtaccaaaga ccaagacaac tgtatcttcg
     2161 ttgataagtg attttggacc gtgacggaag ccaactggac tttcatacat agtcgcaact
     2221 tgaccagctg ttaattccaa aatcttgagc tgagcttcat gagcaagccc aaagaaagga
     2281 ccagcgccta ggtagatgac acgcttaaag tctaggtcaa caagctcttt gacatcttct
     2341 gcattgtcta gaactttacg ggcaagacta gaaacaactt caaaacgttc agatttcaca
     2401 gcaaattcta taggatcaaa gaccaagaga gctgtcaaca tcatagacat aaagctagaa
     2461 gtcatggcaa atccagcgtc attagaagca gctggttgca agagcaagag attacagtca
     2521 tcaccgtgag cttgaagagc caatttacca tctgctgcac aagtaatcgt cacttgataa
     2581 agctcatcca ccaaggattt ggccaaatca acagtcgcca cactttcagg cgagttccca
     2641 ctacgagcaa aagacacaag gacagttgcc acatcttttt tcaaataggt tgctggattg
     2701 gcaacgatat ctgttgttgc aatggcattg aaattccatt tgcgttcgtc atagacttcc
     2761 ttaaagtaag gtagcaaggt atctcccaca taagcagaag tcccagcacc tgtcaagata
     2821 accttaatat agtcatgttt atcagcgatt tcttgtagga aggctgcaat ttcttcacgt
     2881 tttgcttgat aaaattcaaa agcttctctc catacatcag gttgttggta gatttcacgc
     2941 gtagtgattt ctgcacccaa ttcgagcaag tcttcttttg tataatgtag cattgagttc
     3001 ctctttttct attaaatatg ggaatgggag taagctccat tcccatgtat attctatata
     3061 aaatgctcta acgattttca cgttgtcaca tgaattgaat cgagttccaa ctaaaatctg
     3121 taggaaacta gccgcaggct gctcaaagca ctgctttgag gttgccggat aagactgacg
     3181 aagtcagctc aaaacaccgt tttgaggttg cagatagaac tgacgaagtc agtaacatat
     3241 acctacggca aggcgacgtt gacgtagttt gaagagattt tcgaagagta ttattcatct
     3301 tcatcatcat caaaatccgc taacaggtca ttaactttca caatgctttc tgcagcacgg
     3361 ctcttgtagt ccgcatctgc gcctgtaagg ctcgcattga taaattcaat caccattgga
     3421 agattcatcc ctgcgtaaag gtcaatatca cgaccttcca tgatcaagcg actcaccaca
     3481 ttacaaggtg tcccaccgag aagatccgca aagactagga aatcatccaa cccttcaata
     3541 acagcttcaa atttagcagt aaattcttct gggccatctt ctggaagaag agctactgtg
     3601 taaatgttgt cttgtgggcc tgtgctacct ttaagctcct cacagaagcg accatggctc
     3661 accaaaatta atgatttagt cataaggaat tacattccaa gtgcaaagtg accaagggca
     3721 gaaagagcca aagcaagtac gataataata ccgatagctt tagtagagtt catacctttt
     3781 ttaccaagca accagaagat aaaggcagta aagattgctg gaagcaaacg tgggaagatt
     3841 tggttcaaga tgtcttggaa atcaatcatc ttttcaccga ttggcaactt gtaagaaatt
     3901 tcaaagttaa tcactgttgc tacaagagca cccatcatga agacaccaag tacagatgca
     3961 gcgtcaatca aagctgtcaa ggtactttgc atgttgttga taaggttaac cccttctttg
     4021 taagcaaatt ccaactgttt ccaacggaag atgtcatacg ctactgcaac tgcaatccaa
     4081 aggaagatcc cccaaggttg gccagcgata gccatagttg ctgcgactga ccccatgata
     4141 gcaggtacaa gtgaaccaaa gattgtatcc ccaagaggag cgaatggtcc catcaaacct
     4201 gtcttgatac cgttaacagc gtcttttgaa cctacaccat ctttttcttc catggcaagg
     4261 tcaaaaccag cgataatggt atggaagaat ggtgaagtat tgaagaattg agtatgaact
     4321 ttcatcattt ctttcaattc aggagttcca tcaccataca ttttacgcaa ctgaggcaag
     4381 atcatgtaaa ggtaaccaga agcttgcata cgttcgtagt tccaacctaa ttggaaagta
     4441 aacaagctac gtttgttgat ttgattaaaa tcttcttttg taagtttgta attagaattc
     4501 gtcatcttcg atttccccac tttctgatgg tgtagaaggt gctgctacag ctactttttg
     4561 gctatttttg aagtgaagca ctgcaaggaa aatacctacg atagaaatac caatcataga
     4621 caaacctttg aagttgttca cgaaaccaat tttttcagca acttcagcag gaagagtacc
     4681 tacgatacca gcaacagcgc caccaagacc tgttacatat gagtaaagaa cagtcaacat
     4741 agctgtcaaa ccaaatccca tagcaaggta gtgaaggtta cgtttaactg gaaggtaacg
     4801 aagcaagatt gcaaatccaa gacctggaag catacgtcct gcgagtgtca agccatctgc
     4861 aacccatttg taggcttcaa caaagtctac tactgattgt acaaaggcac caccaaaagc
     4921 aagggcaaag aagactggaa gggcacgaga tagagcccac ggaatcgcac caagcaagta
     4981 gttgcgttca atacctttat agtcaaagcg ttcgattgca gcatccacac ggtgagcgaa
     5041 gaaggtagta gtcatacgac caagaacgtc gaagtaagtc aagagagctg ctactggtac
     5101 agcgattgta gtaattgcaa gcggtgcatc aattccttgt gaaacagaga aggctgtcgc
     5161 aagaaccgca ccagaagttg cgtcgatacg agaagcacca ccgaaggtac caaccccaag
     5221 aacgaacagt tgcaagttac caccgataag taaaccagta gtcacatctc ccatgattaa
     5281 accagtaatg aaaccagcaa atacagggga acctgcagat gaaacgatcg tcaactcatc
     5341 acagatttga taagctgagt acaaagtgag aagtaaaatt tgccaccatt gtatcataac
     5401 aatgacctcc taaaaatttt tttcctattt taataagctc aaaaagtctg aaattggatc
     5461 atttggaacc atctgagcag taagtttaac acctttttct gccagtttgt ggaagtcttc
     5521 cacatccttg tctactacgt tgatagaacg tgtaatagaa cgagtttctg gtgtttgaga
     5581 catattccca acattaagag tttcaagtgg tacacctgct tctaccaaac caaggaagcg
     5641 gtccggttta cgagccacga taaagagacg ttggctatcg tatttgccag caagaatatt
     5701 ggctgcagct ttctcaactg gcaaaatact caatttcaca cctggtggtg tcgcaagttt
     5761 caaaccactc ttttcaatat cgttgttgac aacttcgtcg tctacaacca taatgcgtga
     5821 aacatttagt tttccagccc aaagattggc tacttgtccg tggatcaaac gtccatcaat
     5881 acggcatcct acaattgtca taagttttcc ccctttatat gttttagtgt aggtttacga
     5941 gttaaatgaa tctcttcttt atattgacct tctgtttcaa agataatgat gcggttggca
     6001 ccttccttga gatagcaatg agggatataa agtgagagag ttgggccaac gttccaaaaa
     6061 cgtcctagat tctgcccatt gacaaaggca actcccttac caaactcaga caagtctagg
     6121 taagtatctt ttggctcttc gactgtaaag tcataagcgt aaaaggctgg ttgtccttga
     6181 gtccatcctt ttgaaaaatc aattttctca ggattgtcta gtgggagtgg atagtgtttc
     6241 cagtttagta agaaatgcag atccttacag acccctgtcc gaattccctt acgttgcgta
     6301 tccgctaaga acttatgccc atagttgaca cgccccatat tttctatcaa gatatctaac
     6361 ctagatagcc ctttcttttt accttgataa aaaatatctt ccccaatctc tgtctgatat
     6421 tgagttttaa cccactgacc atcgacatac agctgagccc tatctcgacc atcaatgata
     6481 cgaagtcttt cttcttctgc atcccagttt gtttctgttc gataaagtag gtagccataa
     6541 ctttgtccca gctcctccat cttttgagga tagagacttt ctacaggact tgacaagcta
     6601 tctaaggttt caaacaaaga aactttttca actagtggaa tagcatccaa ctccatactc
     6661 tctttgtaga gtggttccaa ctgcggatac tctgaaaaat gtgttgccat catcttcttg
     6721 actgcaagat atttagcagt tggatttcct tcttcatcca gaagggcatc gtaatcataa
     6781 gacgtaactt gtggcaggtc caaagttcct cgagctgagc aaccattcat gaaaccaaag
     6841 tttgtaccac cgtggaacat gtaaagattg atagagcctt gttccaaaac ctctcgaact
     6901 gcatctgcca attccttagg atcccgtgtg ataatcggtt ctttccagcg attaaaccaa
     6961 ccatcccaga actccataca catgagtggc catttcttcc catgttcatc aaagaattcc
     7021 tgcatctgtg aaaagttgta aggtgcctta gaaccaaagt tccctgttac aaagagatca
     7081 tcttctatta aggttccagc tttcagagtt gctctccatg gaccatctga tgtaaagagt
     7141 ggacaggtta cgccacgctc ttccatcaac tgtcgaatcg ctctcaggta agccttatct
     7201 tctccgtaag aaccatactc attttcaacc tgcatcatga gaatattgcc accattgtcc
     7261 aacaaacgag gcaccagtct tggcaataac tgatcatagt agcgaccaac tgcctcgata
     7321 tatgctgggt cggatgagcg aattcgcatg ttcttggtca agagcgaagc tggtaagcca
     7381 ccgaattccc attccgcaca gataaatgga gacggacgca caattgcgta gagacccaaa
     7441 tcctgcgcta tttggagaaa tttctctaaa tccagatcac cttcaaaatg aaactcacct
     7501 tcacgaggct cgtgtaaatt ccaagcaaca taagtctcta ccgtattaaa accaagagcc
     7561 ttcaagttat agagcgaatg ataccaatcc tctggaggaa ccctaaaata atgaatggca
     7621 ccagataaaa tcttaaatga ttttccatcg agatagaaat catctcgtat ctcaaatcgt
     7681 gtcataaaac taccttccga ccgcgaaagt ttgcgctttc atttgttgtt atattaatta
     7741 taaaccaatc tgtttgaatt gtcaatagaa attgtcggga tatttactgc atttttacta
     7801 ttatacacac attcaattag tttcaaacat ttttagaccc atttcaaacg ctctttaaat
     7861 tcggaatata ggacctaaaa taattttgta tagaatacat tgataaaata tgagcaatcc
     7921 ctatatcgct taatttttca aactattatt ctaatttttt attcaaaaga ctactatttt
     7981 tttcgctttt atggtaaaat tttctatgga gaaggaaaat agaggtaaaa atatggcaat
     8041 tcccaaatat caatacataa aagacgaatt aaaaaataaa atcatctctg ggcagtttag
     8101 cagtggagat aaattttaca ctgaagcaga actcatttca atgtacgatg tcagctctat
     8161 cacagttgtt cgcgccttaa acgaccttgc caaagatggc tatattgtcc gccaacaagg
     8221 aaaaggaacc ttcgtttcac gtgcacgcaa acacaagctt gtagagtttt cagatattga
     8281 actcttcaat gctaaagatg ataaggtaac tgttctttca attgaacgcg gaaacaagct
     8341 tgtttacttg gaaaaattgg gtctacgcgg cgatcaattc tactacaaga ttgaacgtat
     8401 ccgcgaatca aacggtgtcg tttatatcta ccatacatcc tacatcccag aacaatatat
     8461 caatgcaaat tatccaaacc ttgaatacta tagttctatc tataatcgtt tcaagttaga
     8521 ctaccacatt cacatgaatg atgaacactt tgaagaaatc aacgaaatag tctttccaac
     8581 tccagaacat gcggcttcag tcctcggagt cgatgaacaa ttccctactg tcctacaaac
     8641 taaaatcacc aaactcgaat caactggcca agttttagaa tacagtgaaa cttacaaacg
     8701 atctgattac tacaagatta aattcatctc atgtgaccgt gatcactaag aagaaagcct
     8761 gagcctaatc gctcgggctt tttctatgct tattatacca caccaaaaag gtagcgctta
     8821 cttatttttg gaagattcta taatttgtgg aatattttat agaaatagaa ccaaaaatta
     8881 tattagatat atatatgcat ttttttccga ccaatctgaa atcttaagtt taaattttat
     8941 atttttttat acttattata gttttttgtc atctcctctt gactctcgtt aatataagaa
     9001 ataaaataag ggcgttgatt tatataatcg ctatcaatat aacaatgcaa tcaggaggtt
     9061 ttgcaatgaa acatgaaaaa caacagcgtt tttctattcg taaatacgct gtaggagcag
     9121 cttctgttct aattggattt gccttccaag cacagactgt tgcagccgat ggagttacta
     9181 ctactacaga aaaccaaccg accatccata cagtttctga ttcccctcaa tcatccgaaa
     9241 atcggactga ggaaacacct aaagcagagc ttcaaccaga agctccaaaa actgtagaaa
     9301 cagaaactcc agctactgat aaggtagcta gtcttccaaa aacagaagaa aaaccacaag
     9361 aggaagttag ttcaactcct agtgataaag cagaggtggt aactccaact tctgctgaaa
     9421 aagaaactgc taataaaaag gcagaagaag ctagccctaa aaaggaagaa gcgaaagagg
     9481 ttaattctaa agagtcaaat acagacaaga ctgacaagga taaaccagct aaaaaagatg
     9541 aagcgaaagc agaggctgac aaaccggaaa cagaggcagg aaaggaacgt gctgcaactg
     9601 taaatgaaaa actagcgaaa aagaaaattg tttctattga tgctggacgt aaatatttct
     9661 caccagaaca gctcaaggaa atcatcgata aagcgaaaca ttatggctac actgatttac
     9721 acctattagt cggaaatgat ggactccgtt tcatgttgga cgatatgagc atcacagcta
     9781 acggcaagac ctatgccagt gacgatgtca aacgcgccat tgaaaaaggt acaaatgatt
     9841 attacaacga tccaaacggc aatcacttaa cagaaagtca aatgacagat ctgattaact
     9901 atgcaaaaga taaaggtatc ggtctcattc cgacagtaaa tagtcctggt cacatggatg
     9961 cgattctcaa tgccatgaaa gaattgggaa tccaaaaccc taactttagc tattttggga
    10021 aggaatcagc ctgtactgtc gatcttggca acgaacaagc tgtcgctttt acaaaagccc
    10081 ttatcgacaa gtatgctgct tatttcgcga aaaagactga aatcttcaac atcggacttg
    10141 atgaatatgc caatgatgcg acagatgcta aaggttggag tgtgcttcaa gctgataaat
    10201 actatccaaa cgaaggctac cctgtaaaag gctatgaaaa atttattgcc tacgccaatg
    10261 acctcgctcg tattgtaaaa tcgcacggtc tcaaaccaat ggcctttaac gacggtatct
    10321 actacaatag cgacacaagc tttggtagtt ttgacaaaga catcatcgtt tctatgtgga
    10381 ctggtggttg gggaggctac gatgtcgctt cttctaaact actagctgaa aaaggtcacc
    10441 aaatccttaa taccaatgat gcttggtact acgttcttgg acgaaacgct gatggccaag
    10501 gctggtacaa tctcgatcag gggctcaatg gtattaaaaa cacaccaatc acttctgtac
    10561 caaaaacaga aggagctgat atcccaatca tcggtggtat ggtagctgct tgggctgaca
    10621 ctccatctgc acgttattca ccatcacgcc tcttcaaact catgcgtcat tttgcaaatg
    10681 ccaacgctga atacttcgca gctgattatg aatctgcaga gcaagcactt aacgaggtac
    10741 caaaagacct gaaccgttat actgcagaaa gcgtcacggc cgtaaaagaa gctgaaaaag
    10801 ctattcgctc tctcgatagc aaccttagcc gtgcccaaca agatacgatt gatcaagcca
    10861 ttgctaaact tcaagaaact gtcaacaact tgaccctcac gcctgaagct caaaaagaag
    10921 aagaagctaa acgtgaggtt gaaaaacttg ccaaaaacaa ggtaatctca atcgatgctg
    10981 gacgcaaata ctttactctg aaccagctca aacgcatcgt agacaaggcc agtgagctcg
    11041 gatattctga tgtccatctc cttctaggaa atgacggact tcgctttcta ctcaatgata
    11101 tgaccattac tgccaacgga aaaacctatg ctagtgatga cgttaaaaaa gctattatcg
    11161 aaggaactaa agcttactac gacgatccaa acggtactgc actaacacag gcagaagtga
    11221 cagagctaat tgaatacgct aaatctaagg acattggtct catcccagct attaacagtc
    11281 caggtcacat ggatgctatg ctggttgcca tggaaaaatt aggtattaaa aatcctcaag
    11341 cccactttga taaagtttca aaaacaacta tggacttgaa aaacgaagaa gcgatgaact
    11401 ttgtaaaagc cctcatcggt aaatacatgg acttctttgc aggtaaaaca aagattttca
    11461 actttggtac tgacgaatac gccaacgatg cgactagtgc ccaaggctgg tactacctca
    11521 agtggtatca actctatggc aaatttgccg aatatgccaa caccctcgca gctatggcca
    11581 aagaaagagg gcttcaacca atggccttca acgatggctt ctactatgaa gacaaggacg
    11641 atgttcagtt tgacaaagat gtcttgattt cttactggtc taaaggctgg tggggataca
    11701 acctcgcatc acctcaatac ctagcaagca agggttataa gttcttgaat accaacggtg
    11761 actggtatta tgttataggc aatcacaaac aagatgaagc ttaccctctt tcaaaagcag
    11821 ttgaaaattc tggtaaagtt ccattcaatc aactagcttc taccaaatat cctgaagtag
    11881 atcttccaac agtcggaagt atgctttcaa tctgggcaga tagacaaagc gctgagtaca
    11941 aggaagagga aatctttgaa ctcatgactg cctttgcaga ccacaacaaa gactacttcc
    12001 gtgctaatta taatgctctc cgcgaagaat tagctaaaat tcctacaaac ttagaaggat
    12061 atagtaaaga aagtcttgag gcccttgacg cagctaaaac agctctaaat tacaacctca
    12121 accgtaataa acaagctgag cttgacacac ttgtagccaa cctaaaagcc gctcttcaag
    12181 gcctcaaacc agctgcaact cattcaggaa gcctagatga aaatgaagtg gctgccaatg
    12241 ttgaaaccag accagaactc atcacaagaa ctgaagaaat tccatttgaa gttatcaaga
    12301 aagaaaatcc taacctccca gctggtcagg aaaatattat cacagcagga gtcaaaggtg
    12361 aacgaactca ttacatctct gtactcactg aaaatggaaa aacaacagaa acagtccttg
    12421 atagccaggt aaccaaagaa gttataaacc aagtggttga agttggcgct cctgtaactc
    12481 acaagggtga tgaaagtggt cttgcaccaa ctactgaggt aaaacctaga ctggatatcc
    12541 aaaaagaaga aattccattt accacagtga ctcgtgaaaa tccactctta ctcaaaggaa
    12601 aaacacaagt cattactaag ggcgtcaatg gacatcgtag caacttctac tctgtgagca
    12661 cttctgccga tggtaaggaa gtgaaaacac ttgtaaatag tgtcgtagca caggaagccg
    12721 ttactcaaat agtcgaagtc ggaactatgg taacacatgt aggcgatgaa aacggacaag
    12781 ccgctattgc tgaagaaaaa ccaaaactag aaatcccaag ccaaccagct ccatcaactg
    12841 ctcctgctga ggaaagcaaa gctcttcctc aagatccagc tcctgtggta acagagaaaa
    12901 aacttcctga aacaggaact cacgattctg caggactagt agtcgcagga ctcatgtcca
    12961 cactagcagc ctatggactc actaaaagaa aagaagacta agtcttttcg ataaaaaata
    13021 aacagcgaga ttgaagctcg ctgtttattt tttaattaat cacctagtcc aagacgttca
    13081 aagatatcat ccactcgttt ggtgtaataa actgggttga agatttcatc gatttcttct
    13141 tgagtgagac gtgatgttac ttctgaatct gcctcaagaa gtggtttaaa gtctacttgg
    13201 ttgtcccaag agtaggctgt ttttggttgc accaagtcat aggcttgctc acgggtcatg
    13261 cctttttcaa tcaatgtcaa catagcccgt tggctaaaga taagaccaaa agtcgagttc
    13321 atgtttcgga tcatattttc tgggaagact gtcaagttct tgacgatatt tccaaaacgg
    13381 ttgagcatgt agtcaatcaa aatggtcgta tctggtgtga tgatacgctc agctgatgag
    13441 tgagaaatat cgcgttcgtg ccagagagcg acgttttcat aagccgtaat catgtgacca
    13501 cgaatgacac gcgccagacc agtcatattt tcagaaccga ttgggttgcg tttgtgaggc
    13561 attgctgaag accctttttg ccctttagca aagaactctt ctacttcgcg ttgctcagat
    13621 ttttgtagac cacgaatctc agtcgccata cgttcgattg aagtcgcaat gctggcaaga
    13681 accgcaaagt actcagcgtg aaggtcacga ggaaggactt gtgtagagat ttcttgggca
    13741 cggatgccaa gtttatcgca gacatactcc tctacaaatg gtgggatatt ggcaaagttc
    13801 ccaaccgcac cagaaatctt accagcttct acaccagcag ctgcatgctc gaaacgctcg
    13861 atattgcgtt tcatttcgct gtaccaagtt gccaatttaa gaccaaaggt tgtcggctca
    13921 gcgtgcacac catgagtacg ccccatcatg atggtgaact tgtgctcctt ggccttgtca
    13981 gcgatgatat tagtgaagtt ttcaaggtca cgacggatga tgtcgttggc ctgcttgtag
    14041 aggtaaccat aagcagtatc caccacgtcg gtagaagtta acccatagtg aacccacttg
    14101 cgctcttcac caagagtctc agaaaccgca cgcgtgaaag ccaccacatc gtggcgcgtc
    14161 tcctgctcaa tttccaaaat acggtcgatg tcaaagtccg ccttcttgcg aatcaaagcc
    14221 acatcttcct tagggatttc ccccaactca gcccatgcct cgtcagagag gatttccacc
    14281 tcaagccaag cacggtattt attttcttca ctccaaatat tcgccatctc agggcgagag
    14341 taacggttga tcatgtgtta atttttcctt tcttcttaag ctgttgggaa taagctatct
    14401 aggtaaacca agatttctac tcaaactcct ctttttcaat aaacacagac gggtaatgat
    14461 ctagtgtatt caaatccgta tccagcggta catcatagat agctaaataa ttttcggggt
    14521 attgtgcagc tagttcttca tatttagctt gtaccttatc ttggtcagca ctggcataca
    14581 acacttcaac aactgctcca gtcttatcct tttcaataaa tgtattaacg ataatttgta
    14641 tcatagactt gtcctaaaaa tcaatccctt ccccaaactc ttccacacta tccggcacat
    14701 cactaaacaa agtcacatgt cccatcttac gattatgctt tgcttctatt ttaccataca
    14761 tgtggaggtg ggcgcttgaa ttttctgtca catattgctc agcagcctcg acatgctgac
    14821 cgaggacatt aagcataacg gctggcgcat ggagtttgat gactggtaat ggtgctccga
    14881 gaacacccag aatatgggtg tcaaactgag agaaatcaca ggcttcaata gaatagtgcc
    14941 cagagttatg tggtcgtggg gcgatttcat tgacaataac gtcatcatca gtcgcaaaca
    15001 tttccacaca gagagttcca gacaagttga gttgttctgc gattcgcact gccatagctt
    15061 tagccttgtc tgctagactt tcagaaatgc gggctggtac gatggtctta gacaggatat
    15121 tgttgcggtg gatattttcc tgaactggga aaaacgtcac ctccttgcca tttcctgaca
    15181 cgatgacaga aatctcaagg tcaaagttga caaattcttc caagacgcag tctgctgagt
    15241 ctgctagcgc ataggctgct tccaagtctg cttctgaacg aataaccttt tgtccatgac
    15301 catcgtagcc accagtcgca gtcttgagga catagttttt cgacaagtcg atatctgcca
    15361 agtctaggct agaagtcacg accttgtagg gtgccacagt gacttgagcc ttgtttgaca
    15421 aaaagtcctt ttcaaaaata cgattttgcg aaatgcggag cagatctgtt ccttgaggga
    15481 gttgtccatc cttgataacg gcatccaaac cgtcagcgtc gacattttca aactcgtaag
    15541 tgaggacatc gcaacggtct gccaactgac ggagggcgtc cacatcgtta taaggtgcca
    15601 caatgatttc cgccacgcga gaggccgggc aatccgccgc aggatccagc gcgataacct
    15661 tgtggcccat gtagatagca gaaatggcca tcatctgacc cagttgaccg ccaccgataa
    15721 ttccgattgt tttagatgag ctcatttgac gactcctctg cgatttttcc ttgttcttca
    15781 gcaaagttgg caagtgcatc cgcaatggac ttatcttcta cagagaggag acggagggca
    15841 aagagagctg cgttagtcgc tccagcttca ccgatagcca tggtcgcaac aggcacccca
    15901 cccggcatct gaacgataga atagagtgaa tccactccac taagagcacg agacttgact
    15961 ggcacaccaa tgactggaag ggttgttttg gcagctacca tgcctggcaa atgcgctgcg
    16021 ccaccagcac ctgcgatgat gatcttgatg ccacgactac gggcttcttc tgcatgtttg
    16081 aacatgaggt ctggtgtacg gtgtgcggaa acaactttct tttcgtaggc tacaccgaag
    16141 cggtctagga cttctgctgt tttttgcatg gttgcccagt cggattttga gcccatgatg
    16201 atggaaatta ctggtttcat ttcttctcct ttttcctctt tttcaacaat caccttagct
    16261 tgtgagggac ggcagcagcc accaaaggtg tctcatgcct aaattggaaa cccaaggtct
    16321 ccaagtttcc ccctgaccag aacattcact gttctggtct tttcaccacg acgaccatta
    16381 tcgtgtttgg cgactacggc gcgttattct tatatcttta cttaattgcc ttgcttccga
    16441 tatctgttcg gtagaagagt ccttctattt tttgttggga tagttcttgg tagatgctgg
    16501 cttgggcttc tttgacggta tctgctgtgg taacgagcat ataaactcgt ccgccgtttg
    16561 agagcagtgc tctgctattt tccgcaaact tagcccctgc atagtaggtg atgacatcgc
    16621 cttctgtctt tgctggcaac tcaacgcccc tttcatagtc tagcgggtag cccttggatg
    16681 cgacaaccac acccagagtc acacccttgt ccgtccacat gatatttggc tccttgctat
    16741 ccaggatatc tgtgatattt tgagcaaagt cagaggtcaa gcgaggcaag ataatctgag
    16801 tttctggatc tccgaaccga gcgttgaact caatgacttt cggtccatca gctgtcagga
    16861 taagccctgc gtaaagaact cccagataag ggcgaccttc tttaatcatc ccttctagaa
    16921 ctggcttgac aatggtgtca accgctgtat caactacact ctgtggtaag tgtggaactg
    16981 gcgcataggc acccatacca cccgtgttag gccctttgtc gccatcgtag gcacgtttgt
    17041 ggtcctgagc cgttggcatg atgtagaact tatcaccatt gacaaaggca aagagtgaaa
    17101 attcctctcc ttcaaggaat tcctcaataa ccacgcgcgc acctgagtca ccaaatttat
    17161 tgtccaaaag catctcatga gcggcttcga ccgcttgctc aaccgtctca gcaacgacga
    17221 cacccttccc aagcgccaag ccatccgcct tgactacgat aggcgcacca tgcttttcga
    17281 tataggcctt ggcttcctcg aaatctgaaa atgtgccata ggctgctgtc gaaacaccat
    17341 atttgaccat gatttccttg gcaaaatcct tggaccactc cagctccgct gcagccctag
    17401 tcggaccaaa ggccttaagc ccagcttggt taaaatcatc cacgatacca gcagcaaggg
    17461 catcatctgg accgataaag gtccaagcaa catcattggt ctttgcgaag tcaatcaatt
    17521 tagaatgttc ggaaatagag atatttacca attccaaacc atccagagtc atcccatcat
    17581 tcccaggagc tacaaagact ttttccacgt cttttgattc aagtaacttt ttagcaatcg
    17641 catgctcacg accaccagaa ccgacaacaa gcagtttcat tcctcaacct cttttgcgaa
    17701 ttatttacca acattatatc aaaaaagttc gttttaatct tgtttcagtt agcattttaa
    17761 gccaaaaaag gaaagaaact gttttcttcc cttttatctt cttaatgtct aaaatgtctc
    17821 acacctgtaa agaccatagt caagccgtat ttattcgctg cttcgatgga ttcttggtca
    17881 cggacagagc caccgggctg gatgatggcc ttaattcctg ctttggcgat ttcttccacg
    17941 ttatccgcaa atgggaagaa ggcatctgaa gcaaggaccg ccccgtccag acgatctttg
    18001 gcttggtcaa tggcaaggcg aacagaagcc acacggttgg tttgacctgg accaacacca
    18061 agtgtcatgt ggtcgttggt cacgataata ccatttgatt tgatgtactt gatagccttc
    18121 caagcgaact caagagcagt cgcttctgtc tcagttggct gacgtttggt caccacttgc
    18181 cagtcagctg ggctttcctt gaccacgtct tgattttgca cgagaagtcc accgactaca
    18241 cctgtgtatt ctgcttccac ttcgctagcc tcttgagcat taaatggcaa ggcaaggata
    18301 cgcaagtttt tctttttatt gatcaaaata gctagcgctt catccgtata gcttggtgca
    18361 atgatgattt cgaggaaaac gccgtgcatc ttctcagctg tcgcagcatc cacctcacgg
    18421 ttgaggacga caatcccacc aaagatagat actgggtcag actcataagc gtagtcccaa
    18481 gcagtctcga tgtcatcagc ttgaccaatt ccacatggat tcatgtgttt gagagccaca
    18541 acggttggac tatctttgaa gtcacggatg atacggatag cagcatctgc atcacggata
    18601 ttattaaatg acaattcttt cccgttgagc tgtttggctg aagcaataga gtaatctgta
    18661 ggcaaagctt tctggtaaaa gtccgcgtct tgttgaggat tctcaccgta acgcattggt
    18721 tgcttgaggt cataagtcaa agtgagtttt tcaggcttgc tttcacccac ttgagctgtg
    18781 aagtattctg caatcaaggc gtcataagcc gctgtgtgac gaaatacttt ggctgctaaa
    18841 cgttggcgag tttcataaga ggtttcgccg tttgctgcca attcgtccaa aaccacagcg
    18901 tagtcagcag gatctaccac aactgtaaca ctggcatgat ttttcgctgc tgaacgaagc
    18961 atagacggcc caccaatatc gatattttca actgcatcag cataagtcac atctggttta
    19021 aggatagttt ccttaaatgg gtaaaggttg accaccacaa ggtcaatgag ctcaatcttg
    19081 ttgtccttag ccgcttccaa gtggctatcc aagtcacgac gagcgagaag ccctccgtgg
    19141 atatttgggt ggagggtctt cacacgaccg tccatcattt ctgggaaacc agtcacatca
    19201 tcgatagcaa tggtatccac cccagcatta tcaagggcaa ccttagttcc acctgttgag
    19261 ataatctccc aaccaagttt tttgagttct tgggcaaatt caacaatgcc cactttgtct
    19321 gagacgctga ttaagacgcg tttagtcatt atattctcct ttttaatcat tagttaaaca
    19381 ccaattaaat gcagtaacag taaaacaaga taagcaaaac caaggctaag catacctaag
    19441 atattgatcc attttctagt ctgtgatttg aacactctta taaaaatttg ataaatcagt
    19501 aagcctacac agacacctag cgtatttaaa gtcaaatccg ttatatctgt tatacctatt
    19561 gctaaaatat actgtaaaca ctcaaacaat aaactaatca agaaacctgt cccgactatt
    19621 cttaaactag ataaattagt ttttatcaaa gggaaacaaa cacctaatgg aataaaggaa
    19681 atcagattaa ataacatttc agcaaaaaca atttttccat cgactattag tggttctgaa
    19741 aatggaatcc aattgatata ccttggagct aagaaaaatg ctataaattc aggatttgtt
    19801 tcaaacttaa ataagattcc ccaagttaat aacatcagat agacataaaa tacatatcga
    19861 gttgtttgtt tagattctaa cattacaaat acctccgttt gaagccgtct tcaacaaaca
    19921 ctgactccaa tttaaaatca aagatatcat atgaatcatc aaaaagtcaa tctgtaaata
    19981 gagccttcac tacttccgga tacaacctgt actctgcttc atgtatgcga gcttcaaatc
    20041 tgtcaatggt atcatcagct agtcgtggca cacgaacctg tttgatgacc tggcctgtat
    20101 ccacacccga atccacccag tgaatggtca caccagactg acccacgcca gcattccaag
    20161 catcctcaat cccatgagct cctggaaatt ctggcaagta ggctggatga atgttgacaa
    20221 tccgaccttc ataagccgac aataaggttg gtccaacgat tttcatgtag cctgctaggc
    20281 aaaccaagtc aatctggtgt tcttccaaga gttcgacaag ggctgcttcg tagtctgcct
    20341 tgctctcaaa ctccttgagt tcaaaagcat aggacagaac gccgagctgc tttgcacgct
    20401 caagcacata ggcatcacga tggtctgaaa agacaaactc cactggaaat tcttcggcaa
    20461 tcacctgaaa atttgagcca ttatcagagg caaaaaccgc tatttttttc atttgataat
    20521 gacactttcg ttttctttct tgacgatgcg accaatttca tagactgctt catccaacaa
    20581 ttcttttaca cgctctacat tttcagggct gaccgccaac ataagtccca cacccatatt
    20641 gaagatttca aacatttctt cgtgtttaat ctgaccatat ttttcaaggg ctttgaaaat
    20701 tggaagcact ggaactttgc tttcatcaat ttcagcagct aggtcatctg caaacatacg
    20761 agggacattt tcgataaagc caccacctgt gatgtgggca atgccgttga ccaactcttc
    20821 tttgatgagc ggcaagacag ccttgacata gatacgagtc ggctcaagta gaacttcctt
    20881 aagtttcttg ccttccaatt ctggtaggac ttcctcacct gtgtaatccg caaagacacg
    20941 acgaaccaaa gagtaaccat ttgagtgaat cccacttgaa acaagtccga gaagaacatc
    21001 tccctctacc acctttgaac cgtcaatgat ttgagatttt tcagccacac cgaccgcaaa
    21061 accagccaag tcatagtcgt cttcgccgta catgcccggc atttcagccg tttccccacc
    21121 gatgagggca gcaccagcct gcacacaacc ttctgccaca ccagcaacca cttgttctag
    21181 cttagctggt tcattcttcc ctgtcgctac gtagtcgaga aaatagaggg gttccgcacc
    21241 tgcagcaatg atgtcgttga cacacatggc cacacagtcc tgcccgatgg tatcgtgctt
    21301 gtcgtacttg atagccaaca tgagcttggt tccgacaccg tcagtccctg aaatcaagac
    21361 gggttcttta accccagtct tggaaaggtc aaacatacca ccaaagccac caagagctcc
    21421 catgacacct gcacgctccg tacgggccac gtgcttttta atccgttcaa caacttcata
    21481 acccgcttca acatccacac ccgactgggc atatgcattt ttatttgtca tttgtttttt
    21541 ccttttcttt aatggagaat ctgtcgccta cttgtaaaaa ctggtctttt cttccaaact
    21601 tctacgatag tcttcttcgt agtcatagag aggcgttggg tagtcaccgt caaagtaagc
    21661 gacacagaga ccaccgttcg gcgcatctgt ttcgatacca atcgactcaa tcaagctatc
    21721 aattgaaaga taagtcagac tgtccgcacc aatgatttgg cgagtttctt cgaccgtatg
    21781 attggctgca atcagctcct gacgggtctg gatatcaatc ccgtagaaac atggatacgc
    21841 tagtgcagga cttccaatgg caacgtgaac ctcagtcgca cccgcttctt tcaagagctg
    21901 aacgatacga cgagaggttg ttccacgtac aatggaatca tccaccatga ccacacgttt
    21961 gcctttgaca acacccgaaa cagcagacag tttcatccgc actccttgct cccgcaattc
    22021 ttgagtcggt tggataaaag ttcgctgggt gtattggttt ttgatcagac ccatttcatt
    22081 tggtaagcct gattcttccg caaatcccat agccgcgctt agggaagaat tgggcacacc
    22141 aactacaata tctgcctcat gcttaaattc tcgcgccaat tgcgctccca ttctcttacg
    22201 tgccgtatgg acattgacac cgtggatatt agaatcaggg cgggcaaagt agatatactc
    22261 catagaacaa atcgccaact gggtatcatc tgtatagctg tcatactgaa tgccctcgtc
    22321 atcaatgatc acaatctcac ctggcttcaa atcacaaatc cactcggcac caatgacctc
    22381 aaaagcacag gtttcagagg aaacaaccac cgctccgttg gccattttcc cgatagaaag
    22441 cggacgaaag ccattagggt caagagccgc aatcaacttg tcctcaaaca gcaagatata
    22501 ggcaaaacca cctttgacaa ggctgagcgc ttccttgatt ttgcccatca ggctaggatt
    22561 atgactgcga cgaatgaggt gagccaagat ttcagagtcc gaagtcgcgc tgaaaattgc
    22621 tcctctttgt tccagttctt tcttgagaga ggctgcattg gtcagatttc cattatgagc
    22681 caaaccaaac tgcatatcgt gaaaacggaa gaggaagggt tggatgttat caacagaagc
    22741 ttcgccagca gtcgcataac gcacatgccc aatcgcacca gctcctgtca atttatccaa
    22801 attagctgga tttctgaaaa cttctgataa aagccccatg tcacgatggc gcttcagttg
    22861 tccttgatca ttggagagga ttcctgcccc ctcctgacca cggtgttgaa gactgtggag
    22921 tccaaaatag gtcaacttag cagcatctgg atgtccccaa ataccgaaaa caccacattc
    22981 ttcattaaga gattttactt cgtatgtcat tttttatacc taattttcat ttgtaatcat
    23041 caagagctag atttacatga cttttacatt actgatacta tctattagaa aatctgtaag
    23101 tcttattttc cagtgaaatg tttaaccgct gatgcgaaca ggtgttggtc tttattgcct
    23161 gggatatttt ggaaaagacc atcctcataa cgttctgagt ggcccatctt accgatgatt
    23221 tgaccattct tgctggtaat tccttcgatg gcatggacag aaccattcgg attgtactta
    23281 gaatccatac ttggtttacc gttaaagtca acgtattggc tgaaaatttg tccattgtca
    23341 cggagctctg caaattcctc agccgtcacg acaaacttcc cttcaccgtg cgaaacagga
    23401 atagcgtgga tatcgcccac ttgcacacca gccaaccatg gtgagttggt attggcaatg
    23461 cgagtttcca ccatcttggc cacgtgttgg ttggcatcat tgtagaagag ggttgggcta
    23521 gtactgttag cagcttcaaa gtttccgtag ggtaggagac ccgatttgac taaggcttgg
    23581 aatccattac aaataccgat aatcaaacca ccacgggcga taaagctatc aatagccaca
    23641 cacacttttt cattaagcag gatattgacg ataaacttag ctgaaccatc tggttcatcc
    23701 gcagccgaga atccaccggc aaagaagaga atattagtct tgtcgatatt gtcaaccata
    23761 gtttcaactg acttgacaat agcttcttca ttcaaggtca cgaatggcac caaattgacc
    23821 tctgcacctt ctttttcgaa ggccttagct gaatcatatt ctgagttggt tcctggaaag
    23881 actgggatgt aaaccacagg tttttcaacc ttttctttgg ctttaatcac aacatctgat
    23941 gccacagctg gtacttcttc tagttctttc gcttgggtaa attctgttgg gtaaacttct
    24001 tccaatgtcc cttgaaatgc actgtcaagc ttgtgtccat ctagcttcac accgttgaca
    24061 gtcagtgtaa agtctgcttt cgtttgtcca accttctcta ctccagcaat ttcttcagga
    24121 gatgtgaaga caaagccgcc taattgagct gtcaaagctg tttcaagttc aggcaaggtc
    24181 acctctgcac caatatagtt tccaaaggta gcaagagcca aactttcaac tacaccaccg
    24241 tatttgacag ctgatgcaga tgtcacttta tggtcagctt ggatggcttc aaactgagca
    24301 aaatttttct taatcaagtc aaaatcaatc tctgcagaga gggcttgacc tgggatgtag
    24361 tagatatttt ccccaacagc tttaaattct ggagagagca ccttacggct atctgccgtc
    24421 gtcaccccaa aggcaaccaa ggttggcgga acggtcaatt cttcaaaggt accagacatg
    24481 gagtccttac caccgataga tggcaagcca agctgaattt gtgcttcaat agaacctaga
    24541 agagcagcta ctggctgacc gaaacgctct gcttgtttat ccatacgctc gaaatactct
    24601 tggtaagaga aacgagcctt ggaccagttg gcaccagcag ccaccaaacg agcagttgct
    24661 tcgataaccg cataagcagc accgtggtat ggagaccatt cagctacata tgggttgaaa
    24721 ccttgagcaa tgaccgacgc agtatgagtc acaccgtgtt gaactggcaa tttctgcaca
    24781 gatgcctcag ttggtgtgag ttggtaacga ccaccaagtg ggtgattaac cgttgagcgt
    24841 ccaacagagc agtcaaagat agtctgtaat cctttttgac ttgcatggtt gaggtcagat
    24901 agaaccgtaa gggtatctga ttccagtgtt tcagcagatg tttgacgctc ttctgggagt
    24961 ttgacatcct tgtccacaac tttggcatcg acaaccacgc gcacaccatt ggtgtcaagg
    25021 aaacgacgct ccaagtcaac gattgtctca ccattccagt gcatgacaag atttggtttt
    25081 tcagttacta tcgccaccac aacagcatca atattttctt tgttacattc ggcaacgaag
    25141 gcatccacat cttcaggacg aaccacgacc gccatccgtt cttgtgattc agagatggca
    25201 atttctgtac cattcaagcc ctggtattta agaggcacct tgttgaggtc gatttcaaga
    25261 ccgtctgcca attcaccgat agccacacag acgccgcctg ccccaaagtc attggacttc
    25321 ttgatcagac gagtgacatt gccattacgg aagaggcgct gaatcttgcg ttcttcgatg
    25381 gcatttcctt tttgaacctc agcaccagca gtctctacag actcaactgt ttgaacctta
    25441 gaagagcccg tcgcaccacc gacaccatca cgacctgttt tgcctccgag aaggatgatc
    25501 acatcacctg cttcaggttt ttcacggaca acattgccct tgggagccgc accaacaacg
    25561 gcaccaagtt ccatacgttt agctacaaag cctgggtgga agtattcacg aacgtaggtt
    25621 gtggcaagcc caatctggtt accatatgaa gaataaccat gagctgctgt tttagaaatg
    25681 acttgttgtg gcaatttccc agcacgagtt tccgaaatcg gtgctgtaat atcaccagca
    25741 cctgaaatac gcatggcttg gtaaacatag gaacggcctg acaacggatc acgaatagct
    25801 ccaccgatac aggtagccgc tccaccaaat ggctcaattt ctgttggatg gttgtgggtt
    25861 tcatttttaa acatgaggag ccaaggttcc ttgacaccat caacatccac ttcaatttca
    25921 actgagcagg cattgatttc gtcagagact tccatatcat ccaatcgtcc gttagcacgc
    25981 tcataacgac cgaaaatagt cgccatatcc atcaaggttt gtggtttttc agaccgacct
    26041 aactcctcgc gcatggcaat atacttgtca taggttgact gcaattgctt ttgaaattta
    26101 gaagctgaaa agtcgatgtg tttcaactct gtctcaaaag tcgtatgacg gcagtggtca
    26161 gaccagtaag tgtccaaaac cttgagttca gtctcagttg gcacgcgccc gattgactta
    26221 aagtagtctt ggataaagag caaatcatcc acttccatgg ccatcccttg ctcggccttg
    26281 tagcgagcaa agtcttctgc tgtatagctt tcaaagaaag tcaattttgg aatggtcttg
    26341 tctgactctg aaaactcctg cttggcaatc cctgtcgtga tatccttgaa acgagaatca
    26401 actggattga gcaggtagtt tttgacagct tccaactcag tcgcatcaat atctttattc
    26461 accaagtaaa gttgggctgt gttgactgtc acgtcactcg aacttcccaa caaaagcaag
    26521 gcttcctgtg acgaagctgc acgctggtca aactgccctg gcagactttc aatggcaaag
    26581 aaagcatagt tagcaagatc cgcctgcaca gatacttcat ctaaaacatg gtcggttccc
    26641 tgctcagaga aaatgtgctt ctctgcaggt gcaaacaagt cctcagccaa gtcaaataca
    26701 tcatatactt gcacaatacg aatacttttc aagcttgaca gtcccacgtt gtgctggagc
    26761 tctctaacca aactctctga cttgacctga aaatcagcct ttttttcaac aaaaatacgt
    26821 ttatccatca attcttattc ctttatttca gctcttgcaa tattcccaaa cagccttgag
    26881 gttgttattt taaaccctgc aacttttccc aaacaatctc ataaacgtcg gttagttctc
    26941 ccaatcctct acggaaaaca tccttatcca tgtggttgcc atcagcgtcc cacaagcggc
    27001 agttatctgg tgaaaattcg tctgccaaga taatcttgcc atccttgtca aaaccgaact
    27061 ctagcttaaa gtcaatcaat ttaagcccaa tctcagcaaa ccagactttc aatagttcat
    27121 tgatacgacg cgtttcttcc ttcaagtagg caatctgctg gtcacccgca atctgtagga
    27181 atttcacatg ctcatcattg ataaatggat catccaaatc atcatttttg tagtaaaatt
    27241 cgacaatcgg agtctccaag gcgattccct catccacacc aaaacgtttt gaaaaggaac
    27301 cagcagtata gttgcggagc acgacttcca aaggaataat cttaaccttt ttattgagtt
    27361 gttccgtgtc tgaaagtttc tccacaaagt gagtcgccac accagccgca tttaatttct
    27421 caaaaataaa agatgaaatc tgattattca agactccctt acctgcaatc tgctccttct
    27481 tgacaccgtt gaaagcagtc gcctggtcct tgtaagttga aataataaga ttttcatcct
    27541 cagttgtata gatatcttta gcttttcccg aatagatcaa ttgttttgac attttaaagt
    27601 tcgcctttcg tattacttga gcacatttta ccacaaaaaa ccaaaaaaca caagaattca
    27661 accgaataaa tagcagatgt ttttcaaaaa ttgtaaagaa aaaactgcaa gaagaatctt
    27721 tctcacagtt taaaaattat ttaactctaa aaacacgaac attactcttt gttcaaaaat
    27781 tgatccaaat aataacgtag gtaacttttc ttgcccgtaa tcatctgtag acggccttcc
    27841 accccgtacc taagtttttc agcctgctcc gaagttagat tagtctccgc ctcgatttta
    27901 aagaaattcc ctttctcagt cttagtagct gtcgcatcaa tacttgtaat agtagaatct
    27961 agaaaaagtt gattcccggc atcatgagtc gtagtatagc gaacagaatc accgaccttg
    28021 attcttgcta catcttttga acttagatag gctgtgagtt tggctttccc ttctctttcc
    28081 aaagatggat aaagttgggc tagtagggca ccttctgcaa ccatgctaga atcactggtc
    28141 tcaggattaa gatgaagcac cccatcctca cttgccgtaa ttttcccctt gtctaaaaga
    28201 tttccctgta ccttcttacc tgactctgcc tccaagattt tctgggctag aagggtcaat
    28261 tcctgaccaa cctttgccaa gtgttgggat ttaagggatt ccaattgact gcttaaccct
    28321 gacgcatagg cttgctgggt acctgaacct gcatactgga cacggtaagt agcaagacta
    28381 gattctaact gagaaatctg tgcttcaacc tgtgcaactg cctgaacctt agtttgggga
    28441 ttttcctcgc cctgagactt gtaggactgg taaagagagt aggctagatt ctgactggcc
    28501 aaggaagcac ctgtttccat agctgactta gctgtctggt aatcgcgaat tttagcctct
    28561 gtttgattga tgaggttgcc gatttcggct tgggtttggc tagctgctgc attctgggac
    28621 gcgatggtct cattttgttg cgatgtacta gccctaagac tgcctgcttg actgatgtag
    28681 tcgcgaaagg tggcttggta gccaaactta tcctcctctg gaaagtggtt ctccccttct
    28741 tgcaggctct tttgcagata ctccaattgc tttttttgat cctttagcat gtccaactga
    28801 ctggcatagg actccgcttg gacaccctct gccccttctt ggtattgaac caaaagatcc
    28861 cccttcttaa ccagcttatt ttcttccaaa tgattgacaa gaatacgatt gttgctagtt
    28921 gactggatat ttgcaaggat acgactaggt tcgacagtag ctctagtgga caagctcatc
    28981 tccttttctg caacagttgc aaagccaagt aaaaacacga gcagaagggc catgggtaca
    29041 atcacactac tggaaaaatt atggtaacga cgattataaa actccgcact ttctaaaaat
    29101 tctggtttca tcctctcctc tttctagcta ttgaccaaat gggcgtaaaa gccaccctgt
    29161 gcaagcaaat cagcatgctt tccttcttcg acaatcttgc cctgatccaa gacaaccacc
    29221 ttctctgtcc gctcagcaat agtcaagcgg tgagcaatga aaatcaaggt cttgtccaaa
    29281 gccatgagat tatcgacaat ccgcttctct gtcaaaatat ccaaactgct agtcgcctca
    29341 tccaaaatca agaccggcgc atctgtcaag agagcacgcg ccaaagcgat tctctgacgt
    29401 tgaccacctg aaatccctgc cccatccgaa gtcaattctg tctgataatt cagtggcatg
    29461 cgctcgatat cctctcgaat ctctgccaat tcgaccgccc gtaagatatc ttcctgtgtc
    29521 gtcccctcct tggctcccaa aagaagattc tccaaaatcg ttccgttaaa gacatagggc
    29581 tgttgaggca gatagtttat gtactggcgc agggcttttt tatcaatctg attgagattg
    29641 acactaccca gactaatctc cccttgactt gggtcgtaaa aattaaccat catcttggcc
    29701 aaagtcgtct tacctgaccc tgaaatcccc acaaaagcca ccttagaccc ttggggaacg
    29761 gttaaattga tatccgacaa gacgtctcga ccatagccat acttgtaatg aacctgcttg
    29821 aaggtcatat ctcccttcat caagctcaaa tcctcaactg ttttcttctc ctcaaactca
    29881 gaagctacta gatacacttc atttagacgg ttattggcaa cctgcgctgt ctgaagcttg
    29941 gtttgcagat tgatgatatt ttccaaagga ttggtaaagt aaaccagcaa ggtattatag
    30001 gtaatcaact gccccaaact catcttgcca tccatgacca gaacagcccc catccagaga
    30061 atgccgacat taagcaagag atgggcaacc tttttcagag ccttttgctg actctctgct
    30121 cgactatagg taaaggattt cttcagataa tccacaaatt ccttgtcaat tttttggtaa
    30181 cgctgacttt cactggtcaa ggacttgata gtctcaatac cgttgatgtc ctcaatgata
    30241 gaagaagaca caaccgcatt ggcttccatg gtatcccgat tcatcttttc aaacggcttc
    30301 ataaaggcaa agataatcac tgtgtagata ggaagcgcca ataaagtcat gaaaaagaga
    30361 ttggtatttt gtgaaaatag aacaagggaa ataatgacaa ccgttgacac atctaggaaa
    30421 atcgaaagga tggtcgaagc cagcgcatcg atgatactgt tagcatctgt aaaacgagac
    30481 acgatttccc ctgtcctgcg tgtcgcaaag aaggacatag ggaggtgaaa aacatgcttg
    30541 atataggaca aaatcacgtc aatcgacaag cgttgcccca aaacaagcaa gagatactcc
    30601 tgagcgtaag acaagatttg ctggaggatg tagacgatga ctagcccaat agaaataatc
    30661 cctagtgtcg aacgcatctg atctggcaca taggtatcaa tgatagactg cagataataa
    30721 gaacccacaa tgttaatcac ggttaccaag agtgttgcca aaacgatatt ggcaatcaag
    30781 ccacgctgct tcactaatat agggataaaa gagaacagac catttttttg ttccttatga
    30841 ggcttgtagt ctggactagg tgccataaaa agagtcactc ctgtccattc ttccgcaaaa
    30901 cgctcacgtg gcagtttggt caacttcacc ccgggatctg gatcggcaat atgaatgcta
    30961 tccttatcct gcccagtcac cacatagtag tggagcaatt tcccttcctt aagcacatgg
    31021 gcaacaaaag gaaaagtcaa atccggcaag tcaaaaagcg tcatatccgc cttaatggct
    31081 cgcgtctcaa aaccaatctc ctctgccacc ttgaccaagc ccaaagccgt cgttccatcc
    31141 atggtcgtct tagccaattc tcgcaagtga gccaaaaaat aataactacc atagtagcca
    31201 aaaaccatgg ctaatgaagc tacaccgcag tccatctgat ccacttgcgg acgatagtga
    31261 cgtttcccaa atttcatatt catctccttt tccctaatac tcaatgaaaa tcaaagagca
    31321 aactaggaaa ctagccgcag gctgctcaaa acactgtttt gaggttgtag ataggactga
    31381 cgaagtcagt cacatatata cggcaaggcg acgttgacgt ggtttgaatt tgattttcga
    31441 agaatataaa ctcatctgat aacaactatc ttaccccaat cactaaacaa aaactggact
    31501 tccttcccaa atgagcctat ctccctccca actgcacttt ttggataaaa aaataggcag
    31561 aacaagagtc ctgcccacta aaaatatgct attgaaagga aaatgatttt ttactgacac
    31621 cctaggcaag cttgaaacaa ataaatcatt gatagtaaca cttacgacat cctatttatt
    31681 acttcaattt ctaatgtctc tgctatttct aagctaccta tggtatgatc tatccctagt
    31741 cagaatagat aacaccgttc taaattacga ttcatagtta ctcctttttt gactcgttac
    31801 tataagactc ctctttacat gcgcaaaata attttgattc agattcatca tttatagttt
    31861 tgattatttt ttaacagatt tttctgtttt cttctccgaa gactttaaaa atttttttct
    31921 aattaaatca tccatataag gaccaaatat accaactact aaaccaataa taaaactttt
    31981 aaaatccata attaccacca acatgtcgct tcataggcca cacctccaag tatagctcct
    32041 cccgcagcac cagttgctgc accttgccat gttcttgttt taattcctag ctgaagacct
    32101 cgtgctactc ctcctccaac acctgctttg gcaaaatctc cccaattgca tccgccacct
    32161 tcaactcaag caagcatctc agtatccata atttcaaatt gtgacatctt ttttgtattc
    32221 ataacgaata cctctttttt atttttaata tttgtcttgt tacaaacttg acaagtttag
    32281 tataacagta tctattaatt tttttcatcc aaatcttgaa ttggcatcga aacgtcttga
    32341 attagctttt ttgtttcaaa atcatctcta tttttaaaaa agatgttttc taatcacttt
    32401 tttactatta gacttcctgc aaaactagaa tcctagttca tgattgataa taccagcaat
    32461 caaattcatt cgtaatccga agcgtttacg atgatttcga taggttgttg aaaacatttt
    32521 aaacgttttt actttggcaa agatattctc aaccttgctt ctctccttag atagcgcatg
    32581 attacaggct ttatcttcaa ctgttagcgg cttgagtttg ctggatttac gtggaagttt
    32641 gtgcttgagg atatatcttc atgagccctt gataaccact gtcagccaag attttaccag
    32701 cttgtccgat atttctcatt tctaaaaacc atctacttcc gttgacttgg aactccgatt
    32761 gctattttcc ttgaatgatt ttaaccacat ctcctacact ttggagttgg tcaatttcct
    32821 catcgctgat ttcgatacta aattcatcct ccagcgtcaa gataaactcc atcaaatcaa
    32881 ctgagtcagc atccaagtcg tctttcagac tcaaggattc tgtcacgaca aagtcctctc
    32941 cctgtcgctc ttggataatg gtcacaatac tgtcaaaaat ttctttttct ttcatctctt
    33001 ttattctcct gaaaattcac gcgcagtctg ggcaactact tctgtttcta gcatggtacg
    33061 aatctggcga atcgtactat aaacagcctt ggcatcgctt gagccatgag tcttgacaac
    33121 aggtgccttg acaccaaaca agaccgctcc accaacatct gaataattga gctgtttttt
    33181 caaacctctg aggctgtcct tgagaaggag ggcacctagt ttcgctcgaa gaccaccacc
    33241 tgtaatagct gtcttgagca agcccatgat tcccatagct gtcccttcga tggatttgag
    33301 cacagcgttt cccgtgaaac catctgccac aacaacatct gcaacaccat tcatcaaatc
    33361 acgcgcttcc acgtttccga taaagttcaa actttcatca gccgccagta attcataagt
    33421 ttccttacga agcgggtcgc ccttgctact ctctgttccg ttgttgagca aaccaacacg
    33481 tggttgcgca atgccacgaa cattcttggc atagaaagaa cctaggacag cgtattgatg
    33541 gaggtgctgg gctgtatttt ctgcattagc accgaggtca agcatgtcaa aacctttccc
    33601 atctacagtc ggcaatgttg acataagtcc aggacggtcg atattcttga tacgacccac
    33661 gatgaagaat ccagcagcca acaaagcacc tgtattccca gccgaaagga cagcgtctgc
    33721 ttcaccatct ttgacagcct tggctgccaa taccatactg gcatttttct tattccgaat
    33781 agctctcgta ggttcatcat ccgaatcaat cttctcatcc gtatggataa tgctgacgcg
    33841 ctctgtcgct gtcagatatt gcttgatttt agcttcatct ccgtagagtt gaacctcgat
    33901 atctgaaaag tcagataggg cttgattgac accctcaacg atggcctgag gtgcgtaatc
    33961 gccccccatg gcatctactg cgattttttt catttctttt cctcttttag taattgtccc
    34021 cagtctgcta gggaatcaat aaatttcttt gattttaggt gaatcccaac gtactcttca
    34081 tatagttgat ccataaattg gcgtagctct tgcttgattc caggcttgag cgaaatggtc
    34141 tccaaagtct caaaatcaat agcttgaaat tgattgagca gataggggat attgggattg
    34201 agatggcaac gtctctcatc ctcatgataa tgctctggac agagacaggc tccatatttg
    34261 aaagaaaagt caaaagcctg accaacccga tggcagaaga cacactcatt aaaattgagg
    34321 ctgattccaa atcgagtcaa aatttgaatt tcaaaaatat tggtcaaaac ctgataatcc
    34381 aagcctgctt ccatcaactc caaagtcttt tgcaaaaaag caaacaaggg agcatcctgc
    34441 tgattgtcct gcaaactagc atctgcaaga gctgccacat aggtcgcata ggccatgaca
    34501 aagaggtcac tattaatctt gggaaaagtc atgacctcat gatagtcttc gatgtaactg
    34561 agtccgtcat cattgattcg caagagaaat cgtgccagca ccaagggctg aataacaggc
    34621 gccagcttag actgaccagc gtgtttgaca aaaaacatgc atttgccaac ctgctctgta
    34681 aaaattttga caagcttgtc atcctcacga aaattgcgat tgtaaagcac caagccttga
    34741 ctcgtgatag actgaatcat gcttctctca tatactcctc aagtcgtttc atggcttctt
    34801 tgatagtctc catgctggct gcataagata ggcggacgta gccttccccg taacgtccaa
    34861 aggctgcacc agggataaag gcaacggcct tcttctgagc aaaatccttc agaaaagcaa
    34921 aggagtcttg attgtagccc gctggaattt tagcaaaaat atagaaggca ccgtctggtt
    34981 tgataatctc aaaaccaaga gcagtcattt tttcgatgat atagtcccga cgctggatat
    35041 attccttctt catgggctcc gcatcatttt taccagccgt caaggcttct accgcagcat
    35101 gttgcgccat ggtatttgcg gcagtgacca agtattggtg actcttgatt aactgggatg
    35161 tgaaggccgc aggagcgaaa atcagcccca aacgccaacc tgtcatggca tgcgatttag
    35221 acaaaccatt gataataata gcctggtctc tcaacatcgt tcctagagac acatgggctt
    35281 cgcctgtgta ggtcaattct gagtaaacct catcacagac aacaaaaatt tcgtacttgc
    35341 gtaaaacagc tgccaaggcc tctaactgct ctcgactgta ggtaattcct gtcggattgg
    35401 ctggatagtt gagaataacc gccttgagct tatcaccctg ctccaaaatg gccttctcca
    35461 acatctcagg agtcaagaca aaaccatttt cagtcgtatc aatctcaaca atttctgccc
    35521 caactaagtt aacaatcggt tcatagcctg gataagcagg agctggcaaa agtaccttgt
    35581 ctccctcttc caaaatagcc gtcaaagtcg cagataaagc ctctgtcgcc ccaattgtaa
    35641 ccaagatttc attttcagga gcatagtcca gttggtactt ttccttaaca aagtcactag
    35701 ctgcctgacg tagagtcagc agaccactca tccctgtata gtaggattgg ttctgatcaa
    35761 tcgctcgctt ggccgcctcc ttgacatggt ctggcgttgt aaaatcaggt tcccccaagg
    35821 tcaaacgcaa gaccccagga atctccgaaa tagcctggtc aaactgacga atcaacgaaa
    35881 cttgaatttt atctaactgt ttattaaagc gcttagttaa gtccatagat acctcctact
    35941 ttcaaaacgt atctctatta tactacaaaa gccccccgac cgcaaaaata cattagagga
    36001 tagctttcca ctttctattt tacttttcct gtttataggt ctataatggt aatagatttt
    36061 atttggaggt ttttatgtca tttctatcaa aaaatggagc aggtatcttg gcctgccttc
    36121 tcatttctat cgtatcttgg tacttaggag gattcttccc tgtgattggc gcgcccgttt
    36181 ttgccatttt cataggcatg ctcctacatc cctttctctc gtcctataaa caactggatg
    36241 ctggtttgac ctttagttcc aagaagttgc tccaatatgc cgttgtcttg cttggttttg
    36301 gtctcaatat ctcgcaggtc ttcgcagttg gccaatcttc actccctgtc atcctgtcca
    36361 ctatctcaat agctctgatt attgcctacc tcttccagcg tttctttgcc ctggatacaa
    36421 aactggctac cttggttgga gtaggttctt ctatctgtgg gggttctgcc attgcagcga
    36481 cagcgcccgt tattgatgct aaggaaaagg aagtagccca agccatttcc gttatctttt
    36541 tcttcaatgt cttggctgcg ctcatctttc caaccctcgg cacctggctt catctatcca
    36601 atgaaggctt cgccctcttt gcagggactg cggtcaacga cacttcctct gtaacggctg
    36661 ccgccagcgc ttgggacagt ctttaccaaa gcaataccct cgagtctgca accattgtta
    36721 aactcacgcg caccctagct atcatcccca tcactctctt tctctcctac tggcaaagtc
    36781 gcgagcaaaa aaataagcaa ggcttacaac tgaaaaaagt cttcccactt tttatccttt
    36841 acttcatcct tgcatcgctc ctaaccaccc ttctgacctc tctcggtgtg tctagtagtt
    36901 tctttacccc tctcaaacaa ctctctaaat tcctcattat catggccatg agtgccatcg
    36961 gtctcaaaac taatctggtc gctatggtca aatccagtgg aaaatccatt gttctcggag
    37021 ccgtctgctg gattgccatc atcctcacca gccttggtat gcagaccctt atcggcattt
    37081 tctaatactc ttcgaaaatc tcttcaaacc acgtcaacgt cgccttgccg tatatatgtt
    37141 actgacttcg tcagttctat ctgcaacctc aaaacggtgt tttgagctga cttcgtcagt
    37201 cgtatctaca acctcaaaac agtgttttga gcagcccgcg gctagtttcc tagtttgctc
    37261 tttgattttc attgagtata acacaaaagg tagcccatca gctacctttt tcttatgctt
    37321 cctcaatcaa gcgagtatgt tctctcttga tacagcgatt catcacgata tcatcacatc
    37381 caccatcacg caaaatctct ttcgcttcta aactttcaag tcctagctgt gcccaaaaaa
    37441 tcttggcatc agctttgaga aaatcacgcg ccacatcggg cagaaattca ctgcgacgat
    37501 aaacattgac aatatctaca ggaaaaggaa tttcagcgag gctagcataa gccttttcac
    37561 ccaagatttc gccacctgcc gccttgggat tgactgggat gattttatag ccccgagcct
    37621 gcatttcctt tgtcactcga ttgctggttg tttcttcacg gtcagacaaa cccaccacag
    37681 caagggtttt actcgttgcg agatactgac gtatcacgcc atcacttgga ttgataaatt
    37741 cttgactcat agaaatcctc ctttttcatc agtatagcac attttgaaaa ggtttgcaga
    37801 attctactac aaaaaaggag gactagcccc ctttttattt agcctcgtac caggttgctc
    37861 cttcattctc atctgcgata agaggaacac tgagttgaat ggcttcttcc atggtttgtt
    37921 tcaccaattt tttcatctct accaattcag atttaggcac ttcaaggacg atttcatcgt
    37981 gcacttgtaa cagcatctta gtctgataac cacctgcaac caaggcttta tccagctgaa
    38041 tcatggcaat cttgagaata tctgctgccg aaccctggat aggtgagttg atagcagttc
    38101 gctccgcaaa accacgaata ttgaagttgc gcgaattgat atctggcaac tcacggcgac
    38161 gcttaaagag ggtctctaca tagcccttat cacgcgcctc ccgcaccact tcatccatgt
    38221 agtttttaat acctggaaaa cgttcaaagt aggtatcaat gtaggctttg gcttccttac
    38281 gactaattcc caaattatta gacaagccaa agtctgaaat cccataaacc actccaaagt
    38341 taactgcctt ggcattgcga cggtcatttg cagtcacatt atcaggacgc tcaatgccaa
    38401 agacccgcat ggctgtcgaa gtatggatat ctgccccctc ttggaaggcc ttaatcaagt
    38461 gctcatcctt agaaatatgc gccaaaacgc gcaattcaat ctgtgaatag tcagagctga
    38521 gtagcacact atcctcccac tctggcacaa aagccttccg aatcaagcgc ccttgttcca
    38581 atcgggcagg aatattttgc aagtttggat ccacactaga caaacgcccg gtctgggtca
    38641 aatcctgcat atagcgagta tgaatctttc catcagccaa aatccagtcc tgcaagccaa
    38701 ttacataagt agattgaatc ttagcaattt gacggtaatc caggattttc ttaacaatcg
    38761 gagcaatagg agcgagacgc tccaacacat ccactgctgt cgaataacct gtcttggttt
    38821 tcttagtgta ttctagagga agtcccaatt tctcaaagag aagcacgccc aactgcttag
    38881 gcgagttgac attaaactcc tcaccagcca gctcgtaaat ctcttgagtc agtttttcaa
    38941 tgacaagctc attttcagcc tgcatctcaa gcaaggtctc tttcttgacc acaatcccag
    39001 caatttccat cttggcaaga acaaaagcca gaggttgctc catatcataa agaagctcta
    39061 attgcccatt ttcgctgagt ttttcaagta aaataggctc tgtttctacc aaaacagcaa
    39121 gtttacaagc taagtgttcc aaaaatttct cacgttcagg aatggccttt ttaacaccct
    39181 taccgtagaa agtttcatca tcaaccaagt aagtctgacc ataaagacta gcgatggtcg
    39241 caatttcatt gtcctccaca gtcgaaagga ggtatttagc caaacggatg tcaaaagcag
    39301 gcgcctgcaa atccacacca aaacgttgca aaagaacttt aaccttctta aagtcataaa
    39361 ctctcagaga tgttttttct aagaaatcct tgaaaatcgg gtcttgcaac agctcaagct
    39421 tgtctgtggc atagagctta tccccacaag accaggcaaa tccaaccaaa ttatccgtat
    39481 ggtaattctc accaaaaagc tcaaagtgga agatagactc ttcactcagc atatcttgac
    39541 tgatttggtc aacaatagta aaatccaaac cctcagccac atcagctgac gacacattta
    39601 aagcctgctt gagctgtttg aatcccatct catcgtaaaa tttcccaaga ttttcaacat
    39661 ctggaccacc atagaccaag tcctctaaac caatcgcaat cggtgccttg gtatcaatgg
    39721 tcgctagtgt tttagacaaa aaggcctgtt ccttgtcatt gatgagattt tccttcatct
    39781 tagaagtctt cattccatca atattttcat aaatcccctc aagcgaacca tgctccagca
    39841 agagcttaat acccgtcttt tcaccgactt tggtcacccc agggatatta tccgacttat
    39901 cacccatgag cgccttgaga tcgataaact gagctggtgt gaggcccatt tcttccatga
    39961 ggtaatctgg cgtaaaggcc tcaaactcag ccacaccttt cttggaaatt tcaaccaccg
    40021 tatgctcatc cgtcagctga atcaaatcct tgtccccact gacaatggta atatcaaaac
    40081 catcctgctc tgctagctta tccagcgtcc caatgatgtc atccgcctca tactgagcca
    40141 gctcatagtg acgaatcccc atataatcca gcaactcacg aatgaaagga aattgctcac
    40201 gaaactcatc aggagtcttg gcccgaccac ccttatagtc cgcatacatc tctgtccgga
    40261 aggtcgtctt tcccgcatca aaagccacca aaatatgact cggctcaacc cgctccaaca
    40321 aatgactcaa catcaactga aaaccataaa tcgcattggt atgcaaacca gccgcattct
    40381 taaaacggtc caactgctga tacagcgcaa aaaacgcccg aaaagctaca gaagacccat
    40441 caatcaataa taattttttc ttatccatac acccattata aaggaaagaa tcaaaaaata
    40501 ccattgggaa gagctagagc aagtattttt caaacttttt ccgaataaat agatagagcc
    40561 agagaattta gtaaacctag atttaaaaat gtgctataat atagtatatt gaatctataa
    40621 tagtacacct tgactgctaa aatatttcta taaattaatt tgactttcct gatagagtta
    40681 ttcacatctt atttcaactc actatagaag gaggaaaagg agggctgggt ggctaacttc
    40741 attatagaac tttcaaaaag atgaaaaaat agcgtcaaag aggctttttt ctctttaaaa
    40801 caggaaatct caaagacaat cttgcgacta tccaaactgt acgaataacg agacataact
    40861 tacttcgcta atactatctt ataaaaagat agaaatgtca agcaaaaatg acaagtattt
    40921 tgataataga cttgccatcc catcaacttt ctactatata aagtatgaac tcatagcaag
    40981 gactcaaact cagccacggt catgcctaat tgctcactcg caacctcagg tgttagaaga
    41041 ccttgacgta ctagatttac taaacctact tttaatccct cttcaaggcc ttcttctcgt
    41101 ccttgttcaa taccttcagc cctagcggtt tccaaggcat agtcctgtgc taacaagact
    41161 tgttcttctc gcatatgtag ttgactaaac attttcctgt cctcctcgga ccagctcttg
    41221 tagtccagca gttgatttgc ttgggtaatg gctcgttgcg gttgctgggt aaagggcttg
    41281 ttgccgaaaa actccaacca tggcttgcga accttgtctt tgctggtttc tctgtatttt
    41341 ttaattccaa gaatgccatc ttaaccagat ggttttcctg tccattgttg gtaatcgcca
    41401 atacctcacc tgttgtgtct tcgcgcatac taaagctatg aaaagccagg tcatctgaga
    41461 aataattact atccacgata gcaatggcgt aaacaggagc gatgtgtttg tagctctagt
    41521 gagtatcacc ttctcgctga cgaatttttt caagattttg attaacctga ctgcacaggt
    41581 aagcccacaa gcgattgatg aaaaaattct gatgatggac ttgaatctca ataattactt
    41641 gagtaccgtt atccaactcc gccaagacgt ctatactggt ataaaaatcc tgcaccgagt
    41701 aaggcatgga gagtaatacg tgaatattgc taccctccaa aatggtcaca tttttggctg
    41761 gcaaatccag catatcgcga ataaattgac aagtgatttc tggattgcta aagattttct
    41821 tagctaccaa gtcattggtt gggctaatgc ccggatgacg tacagtcata tttcttctct
    41881 ttttattata tcacagtttt aaatctagct ttactagatt caccgctact atctatttat
    41941 ttggaaaaaa gacgaaaaaa cctgagaatc atctcaggct tggtcattaa atttttttct
    42001 caatatcgaa aagtggagaa agtggtcgtt tttcatgaat acgtacgata gcatccccta
    42061 ggagatgagc tattgaaatc tgctcaatct tatcaatcaa acgctcttct ggcagataga
    42121 tggtatccaa aacaaccaat ttcttaatag ctgatttttg gatattgtcc gtagcaggac
    42181 cagaaagaac tgggtgcgta cagcttgcat agacttcaac agcaccagct tccgcaagag
    42241 catctgccgc atgacaaatc gttccagcgg tatcaatcat atcatcaatc aagatacaag
    42301 tcttgccttc aaccttaccg atgatgttca taacttcact agtattcatc ttatcaacgc
    42361 tacgacgttt atcaataata gcgatagatg ttttcaaaaa ttctgccaac ttacgagcac
    42421 gagtcacccc tccatggtcc gggctgacaa ccacatagtc agaaccaacc ataccacgac
    42481 gctcaaaata atctgcaatc agaggagcac ccatcaaatg atccacagga atatcaaaga
    42541 atccttgaat ttgcgcagca tgcaagtcga tggtcaataa acgatccact ccagctactt
    42601 caagcatatt tgcgacaagt tttgaagtga ttggctcacg cgctctcgcc tttctatcct
    42661 gacgtgcata cccatagtaa ggcatgacaa cattgacaga ttctgcactc gcacgcttca
    42721 aagcatctac cataatcaaa atttcaagca gattgtcatt tacaggcgaa ctagttgatt
    42781 gtaagataaa gacgtgtttc ccacggattg attcttcaat gttgacctga atctctccat
    42841 ctgaaaattg gcgaacactt gatttcccca actctatccc aatctcctgc gccacacgtt
    42901 ctgccaattc tttattagaa gaaagggcaa acagctttaa atcagaaaaa gacatgattt
    42961 cctccggtat atatgtataa cttgtgcttt tcacaagatt ttccatctac cattgtagcg
    43021 ctttttgcac tatttttcaa tcaaaaataa aagaagggca ccatatttgt acccttgcat
    43081 cattcttttg aaaaatattc taggtcatca actcattatg tttctcaaca aagcaataag
    43141 catgataaaa accatagaga gcaatagccg taaccactgg aatcgctaaa ggcaactctg
    43201 tttccaactc cacaaaagga gagttaaaca agaagtgagt tcccaaggct agacctagga
    43261 aaataagtcc ctgtttcttg ccaatcttct gtcctttata ggctctgtaa agcaagtaaa
    43321 cccccaccac agccagacct gaaaaagtcc agtgagaggc aattcctgag atgatacgct
    43381 ctaaaatcct cgaaatagta aagtcaaatc cctccggtaa atccgtacga atatagccaa
    43441 tatcctcaat catttggaat cccaaaccag aagcagtccc tagtaaaaac aaagatttta
    43501 attttcgcac aggaatcaaa gctaaaacaa aaacaagtgg caacaatttc aagggctctt
    43561 ctaccaaagg agccacaatc gcactttcaa aggcatttaa aaaagcacta tctgggaaaa
    43621 gaccacccag taaatcatgg atataggtat tcgcaaagct agacaaccag cctgaaagga
    43681 acatcccacc caataaagac aagatcaagg cgttctttgg caattcccat tttttcccaa
    43741 tacggaaaag gaaataaaga gccggaatca tgtaaaagag agctagaaag atagaaactc
    43801 ccattagtcc atattccgcg cctgatatcg aaccatccgt atagtagatg gtttcatact
    43861 gtaaaccaat acatagcaat aaaataaaaa taaataaaat actgtttttc ttcatacact
    43921 ttctttctaa atgaattttt tacaattcta caactgtcat acttcctgta tccacatcgt
    43981 aaatggcacc agagataatg acatcgtctg gtattaggga agattcgata agcagtttca
    44041 tatcctctcg cacactctcc tctatatctt ggaagggcaa gaagtcctgg tctgacatat
    44101 cgacacctag ttcctctttc agatactcct gaaaaggacc attttcaaag gtctgagcac
    44161 cacagtctgt atggtgcagc accacaatct ctcttgtccc catttgttgt tgggaaataa
    44221 ctagcgaacg aatcatgtcc tcagtcactc gaccacctgc attccgcaag atatgagcat
    44281 ccccaagtgc caagcctaga gcttgtgcaa cgtgcagacg tgagtccata caggtcacaa
    44341 tggctactct tgttttgggt ttaagtggca gatttaactg cccatgtagg gcaacataag
    44401 cctgattggc ttgcataaac tgttcaaaat acgacacgat tccctccttg aaaatttgat
    44461 agtcaaatat ttctcctatc ttatcatttt taagaggatt tgtcacggat tatgcaaaaa
    44521 cctttttcaa aacttcctga atggtagtca caccaatcac ctgaatttcc ttgggcggag
    44581 tgatccctgt caaagaattt ttgggtacat aaatcttagt aaagcccagt ttagcagctt
    44641 cgttgatgcg ttgctcgata cgattcacgc gccgaatctc tcccgtcaag cccagttcgc
    44701 ctacaaaaca ttcctgagga ttggtaggct tgtctttata gctcgaagca atagcaaccg
    44761 caacggccaa gtctatcgca ggttcatcca atttgacacc gccagcagat ttgagatagg
    44821 catcctgatt ttgcaagaga agacctgccc gcttttccaa aacagccata atcagactag
    44881 cacgattaaa atcaagtcct gtcgtcgtac gcttagcatt tccaaacatg gtcggtgtca
    44941 ccaaagcctg aacttccgcc aaaatcgaac gcatcccttc catggtcaca acgattgatg
    45001 aaccagtcgc tccatccaaa cgctcttcta ggaaaacttg actcggattg agtacctcaa
    45061 ccaaaccgcc cgactgcatc tcaaaaatcc caatttcatt ggtagaacca aaacggtttt
    45121 tgaccgctct caagatacga aaggtatggt ggcgctcccc ttcaaagtaa agcaccgtat
    45181 ccaccatatg ctccaacata cgaggtccag ccaaggtacc ctccttggtc acatgaccta
    45241 cgataaagat ggcgatatta tttgtcttag ccaactgcat gagctcagcc gtcacctcac
    45301 gcacctgaga aacagacccc tgcacccctg aaatctcagg agacataatg gtctgaatgg
    45361 agtcaataat aaggaaatct ggttggatgc gctctacttc tgcacgaaca ctctgcatat
    45421 tggtctctgc atagaggtaa aactcgctat caatatcacc caagcgctct gcacggagtt
    45481 taatctgctg ggcagactct tcaccactga cataaagaac cgttccaact tgagacagct
    45541 gggtagagac ttgtaggaga agggttgatt ttccaatccc aggatcccca ccgatgagga
    45601 cgagacttcc tggtaccact ccgcctccaa gtacacggtt gaattcctcc atctccgtct
    45661 tggttcgatt gacattgatt gaagtcacct cagccagttt catgggcttg gttttctcac
    45721 ctgtcaagga cacacgcgca ttcttgacct cggcaacctc aatctcttct acaaaagaag
    45781 accaagaccc acagttgggg catcgtccca gatatttagg ggaattatac ccacaatttt
    45841 gacatacaaa tgtcgctttt ttctttgcga tgataaacct ctttctatat ctctaactca
    45901 cactcaatca cttggcaaaa atcaatcttc tcatttggca caaactggcg catgagcatt
    45961 cgatgagcaa caactaccac agtctgatgt tctcgatact tagacataca ttctagaaac
    46021 cgagacttca tttccgtagc tgtctcatat tgaataggac tattaggaag taactccccc
    46081 ctgttttcta aaaacagtct tctagctgtt tcaaagtttt ctattcctgt tttatagacc
    46141 tgccattcat gtaataaagg ctctactctt aaaggaagac ccgtagcaca gaccacatac
    46201 gaagccgttt ctaaagctct tgcgactgca gaagatacga ttatttcagc tgacgagagt
    46261 aaaggatttt tgctcaattt ctggacttgc tgccgtccca tatcagacaa gggtgccaaa
    46321 tctatcccaa atcctatata agaacgctcc tctaactcac ggtaatctgg ctccccatga
    46381 cgtacaaaga taatcttcat tctagtgccc tgtcgatcca aatccaccag ttcgaacgcc
    46441 atcagccgca tctccatctg caattaagaa agtagcaaaa acagcctgga caatacgctc
    46501 cccaacttca agaacaacct cttggtctgt gatattcttc atctgcgcaa aaatatgccc
    46561 ttcatttcca ggatttccat aataatcccc atcaatgacc ccaactgagt taattaaaac
    46621 caagcccttc ttacgaggat ttgaagaacg atcatagagg tagagaacct cagtcggctg
    46681 catataagcc ttaacccctg tcggaaccaa gacaatctct cctggcgcaa caactgtacg
    46741 cacagcaacc tttaagtcgt aaccagccgc atgcgctgtc tcacgcttgg gcaataaatt
    46801 ttcatctgta aaactcgaaa ccaattcaaa accacgaatt ttcataattt tctcttttct
    46861 attatcattt attctagatt attctatctt atttattcgg aaaaagcacg aaaaaaagag
    46921 cacacaattc aaatcgctta gggctgctgg attcctcccc tgacccgctt cacgcagaac
    46981 tgttgctcca ctatttatta tatcacattc ctattcattt taaaagcaaa attatttttt
    47041 ccgtctattt ctaaaaaagt cctgcataat agctgcgcat tcatcttcca aaattcccgt
    47101 ttcaacctct acacgatggt taagacgctc atctgtcaag atatcgtaca aacttccagc
    47161 agcgccaaat ttctggtttt tagccccata gaccacattt ggaatacggg caagcccaat
    47221 cgccccacta cacatgacac aaggttcaat ggtcacaaaa agtatgcaat ccagcaagcg
    47281 ccagctctcc tcactcaagt tcgcatcctc tatagccata atttccgcat gcataaccgc
    47341 tcgctgtaat tcctcacgcg cattatgccc acgaccaatg atttccccat ctttgacaat
    47401 cacacaacca attggaattt catcgtgttc aagagcaatc tcagcctctc tcaaagcctc
    47461 cctcataaag acttcttttt cttcaagcgt ataatacatc tcttttctct tttcctactt
    47521 atcgatttta ttattatatc atgaatccca acacaaaaaa agccaccgaa tgcggtgact
    47581 ctatagggag attattatga aaaagaaaag tttaggatat ttgttacaac aagttaggag
    47641 gtcttcttgt aactgtctat agtatacccg acctatctta aacaaatctt aaaaatctct
    47701 taggaccaaa cactttctaa aatatttgtt tgttcacgac caggacctac tgagaaagta
    47761 gaaatacgaa cgccaaccaa ttcactcaca cgacgaacat agttacgcgc attctcagga
    47821 agatcttcca aattgcgaac tccggtaata tcttctgacc aacctggcaa ctcttcatag
    47881 ataggcttgc aacgtttcaa ttgctcaaga ctagctggat agtagtcaat acgttgaccg
    47941 tcaagatcat aggccacaca gattttcaca gtatccaaac cgctcaaaac atcaatagag
    48001 ttcaaagaaa ggttagtaat accagaaaca cgacggctat gacgcatcac aactgagtca
    48061 aaccaaccta cacgacgtgg acgaccagtt gttgtaccat actcatgacc cacttcacgg
    48121 atacgttctc ccacttcatc aaacaactca gttgggaaag gaccatctcc tacacgactc
    48181 gtataagctt tacatacacc tacaaccttg tcaatcttgc ttggaccgac accagaacca
    48241 attgtcacac caccagctac agggtttgat gacgtaacaa atggataagt accttggtcg
    48301 atatctagca taacaccttg tgcaccttca aaaagcacac gtttgccatt atcaagcgca
    48361 tcattcaaga taacagatgt atctatcacg tatttcttga tttgttgacc atattcgtaa
    48421 tattcttcaa aaatatcatc gaaaacaatc tctttactgt catacaattt ttcaaaaaga
    48481 cgattctttt cagcaaggtt acgttctaaa cgctcacgga aaatatcttt atctaaaaga
    48541 tctgcaatac gaattccaac acgagcagcc ttgtccatat aagctggacc aattccctta
    48601 attgtcgtac caatcttatt gtcgccctta gcttcttctt gcaagcgatc caactcgata
    48661 tgataaggca aaataacatg cgcacgatca gaaatacgca agttatcagt tgttacacct
    48721 tcctcatgaa gatagctcaa ctcttttaca agagatttag gatttacaac cataccattc
    48781 ccaatgacag atattttttc agggaagaaa atcccagatg gaatcaagtg caacttaaat
    48841 ttcttaccgt caatcacaat cgtgtgacca gcattatcac caccttggta acgtgcaatc
    48901 acttctgcat tcgctgaaag gaagtctgta atcttccctt taccttcatc accccattgg
    48961 gtacctacaa caacaactga agtcataatc ttgtctgagc cctcaggctc ttcctttctc
    49021 acatacatgg caggactctc acctgcaatt atatcttaca atttattata ataaaaaatc
    49081 gcctttttat caagaagaaa caatagaaag atttgctatt tccaactatt aaaaaatgat
    49141 ttagaaaaat tactagctat ttactattat ctttccataa aagagtaaat tagttcggaa
    49201 atttagtaaa attacctcaa caagaaataa aaccccgatt cattaccaat ttttcaagat
    49261 acaaacgata agcaacacga taatggtaaa cgataaaatc cctacgacaa ccaatgccat
    49321 atctcactaa ataataaatt aaaaatttaa aatgaacatg ttcccagtca aaattatcac
    49381 caaatgtagg accatactct tcttcaatac tatcatagaa attagccatc tgctcataaa
    49441 ttttttgtaa cataatcaaa tactcctttt cttttttata aacttattct aacaaaaaat
    49501 tttacacatt cactatcaat tcctgaattg ttaaaatacc agcctcaaca agataaaaat
    49561 aggaaaagtt gacagaatag aaacaaattt gctacctaaa tttcaaacga ttaaagttct
    49621 aaaaagaccg ccttaaaact tttgggtaaa tcctattaga actataatat ttttatatag
    49681 gtattatggt tctgattttc tagtataaaa aaattcaaac tagaattttt cttagaaaag
    49741 gccgttttaa gtgctatcat tgctcaaaaa tggaggtcgc tgagacttct atcgtcaaga
    49801 agaatcacca aatccctcgt atcatcaacc aaaagattgc tcaaaagtta attgaaaaga
    49861 tttctatgac cgatattgct catcagctat cagctggcca ttttaacttc aactgtcatt
    49921 cgaaagctca atgacttcca ctttgagcat gatttttcgc gtcttcctga gattatgtcc
    49981 taggacgttg aaacagtccg gggagtgact gtttcaatcg ggagatggag atgagcttta
    50041 ttgctcagga ctttgataag ctcaatatca taactgttct tgagagcaga acacaagcca
    50101 tcatccgaaa tcccatggat acaaggctat caagcgctac tggaagctca ttcaacaaga
    50161 tagtcagaaa ctgagtgata aacgatttta tcgccctact tttcgtatgc acttgactaa
    50221 taaagaaatt ctagataaac ttttgagcta ttccgaaaac ttgaaacacc actataatct
    50281 ctatcagctc ttgcttttcc acctcttttt cagactctgt ttaaaacctt cctcaaagat
    50341 aaagagaaaa tcgtcaacgc ccttcaatta ccttattcca aattccaacg ccaaactgga
    50401 agccaccaat aatctcatca aacttatcaa gcacaatgcc tttggtttta ggaactttga
    50461 aaacttcaaa aaagaaagga cgaaatttgt cctttctata tcttcgcttt cttcaaccca
    50521 ctacagttga caaagaaccg aaaaatgtct cgcctctaat atagtcaatt gaaacaagaa
    50581 caagacaaaa gagcctcgta aaaggtattg caacgtggta ataccttttt gaggttcttt
    50641 ttgatatgag cccatgtttt ctcaatagga ttgtactcag gtgagtaggg aagaagaggt
    50701 aaaagtttat gcccaaactc ttcacataaa agttctagct tacccattct atggaatctt
    50761 gcattgtcca taatatagta gattgaaact agaatagtac acctctactt ctaaaacatt
    50821 gttagaattc gattttactg tcctgatcga tttgtcctat tcttatttca ttttactata
    50881 acacgaaata tattattatt acataacaaa aaagaggtct aaacctctta actaaattac
    50941 tccgccagta ggactcgaac ctacgacatc atgattaaca gtcatgcgct actaccaact
    51001 gagctatggc gga
//
LOCUS       DAVDZK010000012        48914 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVDZK010000012 DAVDZK010000000
VERSION     DAVDZK010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48914
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.012"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            91..789
                     /locus_tag="VUX16_000801"
     CDS             91..789
                     /locus_tag="VUX16_000801"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET8123796.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            780..4319
                     /gene="smc"
                     /locus_tag="VUX16_000802"
     CDS             780..4319
                     /gene="smc"
                     /locus_tag="VUX16_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET8123797.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLHRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLGSEEATLKTLQDEMARLTESLEAIKFQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKENCQERLATIARDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEQVAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKMQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            4316..5110
                     /locus_tag="VUX16_000803"
     CDS             4316..5110
                     /locus_tag="VUX16_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET8123798.1"
                     /translation="MTIKLVATDMDGTFLDGSGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            5110..5928
                     /locus_tag="VUX16_000804"
     CDS             5110..5928
                     /locus_tag="VUX16_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET8123799.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDDHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYTKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPNNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAVANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            5932..7221
                     /gene="ftsY"
                     /locus_tag="VUX16_000805"
     CDS             5932..7221
                     /gene="ftsY"
                     /locus_tag="VUX16_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET8123800.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDIEPAFTEAEEVS
                     QEEAEVESSEESVFQEEDSQDTVEENLDLEPVVEVSQEEVEEFPNSQEVTEEEKLEHE
                     GTIEENNSEVLEPETPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVTEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(7267..8754)
                     /locus_tag="VUX16_000806"
     CDS             complement(7267..8754)
                     /locus_tag="VUX16_000806"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET8123801.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKFFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(8903..9643)
                     /locus_tag="VUX16_000807"
     CDS             complement(8903..9643)
                     /locus_tag="VUX16_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET8123802.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(9643..11808)
                     /locus_tag="VUX16_000808"
     CDS             complement(9643..11808)
                     /locus_tag="VUX16_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET8123803.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYQIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            11981..12934
                     /locus_tag="VUX16_000809"
     CDS             11981..12934
                     /locus_tag="VUX16_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET8123804.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLTILISSVLFTLLHVGNAGLTPLS
                     LVNLFLFGVAMALYLLKIDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            13011..14999
                     /gene="uvrB"
                     /locus_tag="VUX16_000810"
     CDS             13011..14999
                     /gene="uvrB"
                     /locus_tag="VUX16_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET8123805.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            15009..15572
                     /locus_tag="VUX16_000811"
     CDS             15009..15572
                     /locus_tag="VUX16_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8123806.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            15538..16047
                     /locus_tag="VUX16_000812"
     CDS             15538..16047
                     /locus_tag="VUX16_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8123807.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQMWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAIGDLKVVGFISYGNFRDETMQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            16100..16567
                     /locus_tag="VUX16_000813"
     CDS             16100..16567
                     /locus_tag="VUX16_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET8123808.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRSPDTNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLRS
                     SEEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYRHRTEDDWEKKIF"
     gene            complement(16564..17079)
                     /locus_tag="VUX16_000814"
     CDS             complement(16564..17079)
                     /locus_tag="VUX16_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET8123809.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALEQLGYLVKD"
     gene            complement(17091..17618)
                     /locus_tag="VUX16_000815"
     CDS             complement(17091..17618)
                     /locus_tag="VUX16_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET8123810.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(17900..18463)
                     /locus_tag="VUX16_000816"
     CDS             complement(17900..18463)
                     /locus_tag="VUX16_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET8123811.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(18447..18998)
                     /gene="coaC"
                     /locus_tag="VUX16_000817"
     CDS             complement(18447..18998)
                     /gene="coaC"
                     /locus_tag="VUX16_000817"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET8123812.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(19010..19699)
                     /gene="coaB"
                     /locus_tag="VUX16_000818"
     CDS             complement(19010..19699)
                     /gene="coaB"
                     /locus_tag="VUX16_000818"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET8123813.1"
                     /translation="MKILVTLGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEIQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            19930..21600
                     /locus_tag="VUX16_000819"
     CDS             19930..21600
                     /locus_tag="VUX16_000819"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET8123814.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRAVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVTKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            21928..23103
                     /gene="mutY"
                     /locus_tag="VUX16_000820"
     CDS             21928..23103
                     /gene="mutY"
                     /locus_tag="VUX16_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET8123815.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            23159..23863
                     /locus_tag="VUX16_000821"
     CDS             23159..23863
                     /locus_tag="VUX16_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET8123816.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            23856..25205
                     /gene="vicK"
                     /locus_tag="VUX16_000822"
     CDS             23856..25205
                     /gene="vicK"
                     /locus_tag="VUX16_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET8123817.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            25207..26016
                     /locus_tag="VUX16_000823"
     CDS             25207..26016
                     /locus_tag="VUX16_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET8123818.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVNS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            26107..26349
                     /locus_tag="VUX16_000824"
     CDS             26107..26349
                     /locus_tag="VUX16_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET8123819.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            26351..26605
                     /locus_tag="VUX16_000825"
     CDS             26351..26605
                     /locus_tag="VUX16_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET8123820.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            26652..27428
                     /locus_tag="VUX16_000826"
     CDS             26652..27428
                     /locus_tag="VUX16_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET8123821.1"
                     /translation="MNKKWLFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELHRMIKDLVEKIS"
     gene            complement(27684..28670)
                     /locus_tag="VUX16_000827"
     CDS             complement(27684..28670)
                     /locus_tag="VUX16_000827"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET8123822.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            28864..31332
                     /gene="gyrA"
                     /locus_tag="VUX16_000828"
     CDS             28864..31332
                     /gene="gyrA"
                     /locus_tag="VUX16_000828"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET8123823.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDVVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQFLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            31332..32075
                     /gene="srtA"
                     /locus_tag="VUX16_000829"
     CDS             31332..32075
                     /gene="srtA"
                     /locus_tag="VUX16_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET8123824.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            32319..33116
                     /locus_tag="VUX16_000830"
     CDS             32319..33116
                     /locus_tag="VUX16_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET8123825.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVGMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            33264..34523
                     /locus_tag="VUX16_000831"
                     /pseudo
     CDS             33264..34523
                     /locus_tag="VUX16_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            34619..35893
                     /locus_tag="VUX16_000832"
     CDS             34619..35893
                     /locus_tag="VUX16_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET8123826.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            35903..36781
                     /gene="truB"
                     /locus_tag="VUX16_000833"
     CDS             35903..36781
                     /gene="truB"
                     /locus_tag="VUX16_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET8123827.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAIGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSQLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            37022..37324
                     /locus_tag="VUX16_000834"
     CDS             37022..37324
                     /locus_tag="VUX16_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET8123828.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            37432..38070
                     /gene="udk"
                     /locus_tag="VUX16_000835"
     CDS             37432..38070
                     /gene="udk"
                     /locus_tag="VUX16_000835"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET8123829.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            38198..39538
                     /locus_tag="VUX16_000836"
     CDS             38198..39538
                     /locus_tag="VUX16_000836"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET8123830.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            39516..39728
                     /locus_tag="VUX16_000837"
     CDS             39516..39728
                     /locus_tag="VUX16_000837"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET8123831.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            39725..40600
                     /locus_tag="VUX16_000838"
     CDS             39725..40600
                     /locus_tag="VUX16_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET8123832.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            40593..41408
                     /locus_tag="VUX16_000839"
     CDS             40593..41408
                     /locus_tag="VUX16_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET8123833.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMIQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            41401..41832
                     /locus_tag="VUX16_000840"
     CDS             41401..41832
                     /locus_tag="VUX16_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET8123834.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            41839..43506
                     /gene="recN"
                     /locus_tag="VUX16_000841"
     CDS             41839..43506
                     /gene="recN"
                     /locus_tag="VUX16_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET8123835.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKERIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKINKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDNVTEAALTQARELLRNREK"
     gene            43508..44236
                     /locus_tag="VUX16_000842"
     CDS             43508..44236
                     /locus_tag="VUX16_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET8123836.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHEAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDSKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHYFIENDGFVAED"
     gene            44315..46138
                     /gene="lepA"
                     /locus_tag="VUX16_000843"
     CDS             44315..46138
                     /gene="lepA"
                     /locus_tag="VUX16_000843"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET8123837.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGDTYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPVINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPEPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNGKTFDVTEVGIFTPKAVDRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAESLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNQTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEE"
     gene            46551..47027
                     /locus_tag="VUX16_000844"
     CDS             46551..47027
                     /locus_tag="VUX16_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET8123838.1"
                     /translation="MGLDHFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVYNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEPLYAYIAEAIA"
     gene            47066..47371
                     /locus_tag="VUX16_000845"
     CDS             47066..47371
                     /locus_tag="VUX16_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET8123839.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGFDVHCDAVMVKDVN
                     EDLIKGYDIFTPIAATDLGFDPGIPVIEAGLILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            47419..48894
                     /locus_tag="VUX16_000846"
                     /pseudo
     CDS             47419..48894
                     /locus_tag="VUX16_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
BASE COUNT        14764 a         8839 c        11093 g        14218 t
ORIGIN      
        1 ccaaatcccc tccagtcccg ttttaaagtg actcaggggg ctttttttga tataataaaa
       61 aggactgtta tcagttagaa agaggttagt atgaaagaat tacaaactgt actaaagaat
      121 cattttgcaa tcgaatttgc agacaaaaat ttactggaaa ctgcctttac tcatacgagt
      181 tatgccaatg agcaccgcct cttaaaaatt tcacacaatg aacgcttgga atttttagga
      241 gacgctgttc tacagttatt gatttcagaa tatctatata aaaaatatcc taaaaagcct
      301 gaaggtgacc tatcaaaact ccgtgctatg attgtccgtg aggagagttt agctggtttt
      361 gcgcgtgatt gccagtttga ccagtttatc aagttgggta aaggggaaga aaaatctggt
      421 ggtcgcaatc gtgacaccat tcttggtgat gcctttgaag cctttcttgg tgcccttctt
      481 ttggataagg atgtggccaa ggtcaaggaa tttatctacc aagttatgat tcctaaggta
      541 gaagcaggcg agtttgagat gattacagac tacaaaaccc atctccaaga gttacttcag
      601 gtcaatggtg atgtggctat tcgttatcag gtgatttctg aaacagggcc tgctcacgat
      661 aaggtctttg atgtagaagt tcttgttgaa ggtaagagca tcggtcaagg ccaaggtcgt
      721 tctaagaaat tagcagagca ggaagctgcc aaaaatgccg ttgagaaagg gctggattca
      781 tgtatttaaa ggaaatcgaa attcaggggt tcaagtcttt tgctgataag accaaggtcg
      841 tttttgacca aggtgtgacg gcagttgttg gacccaatgg atctggaaag tccaatatta
      901 cagaaagtct gcgttgggcc ttgggggagt caagtgtcaa gagtctccgt gggggcaaga
      961 tgccggatgt catctttgct gggaccgaaa gtcgcaaacc gctcaattat gcttctgtag
     1021 ttgtgactct ggataatcat gacggattta tcaaggatgc aggccaagaa atcagggtag
     1081 aacgccatat ctatcgtagt ggagatagcg aatacaagat tgacggcaag aaagtccgtc
     1141 tgcgtgatat tcatgacctt ttcttggata caggtttggg acgagattcc ttctctatca
     1201 tttcccaagg gaaggttgag gagattttta attctaagcc tgaggaacgc cgagctattt
     1261 ttgaagaagc tgcaggagtt ttaaaataca agactcgcag aaaagaaact gagagtaaac
     1321 tgcaacaaac tcaggataat ctagaccgct tagaggacat tatctacgag ttggataatc
     1381 aaatcaagcc tcttgagaag caagctgaga atgcccgtaa gtttttagac ttggaaggac
     1441 aacgtaaggc tatttattta gacgttctgg ttgctcaaat caaggaaaat aaggcagaac
     1501 tagagtcgac agaagaagag ctggctcagg ttcaagaact cttgatgagt tattaccaaa
     1561 agcgtgaaaa attagaagaa gaaaatcaaa ctcttaaaaa gcaacgccaa gatttacagg
     1621 ctgaaatggc caaagaccaa ggcagtttga tggacttgac tagtctgatt agtgatttag
     1681 aaagaaaatt agccctatcg aaactggagt ccgagcaagt ggccctgaat caacaggagg
     1741 cacaagctcg tttggctgct ttggaggata agagaaattc actcagcaaa gaaaagtatg
     1801 ataaagaaag ctctttagct ctgttagagg gaaatctagt ccaaaataat caaaaactcc
     1861 atcgtttaga agctgaattg ctggctttct cagacgatcc tgatcagatg attgagctct
     1921 tacgtgaacg ctttgtagct cttttacaag aagaagcgga tgtctcaaac cagttgaccc
     1981 gtattgagaa tgagttggaa aatagtcgtc agctttctca aaaacaagca gatcaactag
     2041 aaaagctgaa agagcaattg gctatagcta aagagaaggc tagtcagcaa aaggaagagc
     2101 ttgaaactgc caaggagcag gttcagaaat tattggctga ctaccaagct attgccaagg
     2161 agcaagagga gcagaaaact tcctatcaag ctcaacaaag ccaactcttt gaccgtctgg
     2221 ataatctcaa aaacaagcag gccagagctc aaagtttgga aaatatcctg agaaatcata
     2281 gtaactttta tgcaggtgtt aagagtgttc tccaagaaaa agatcgccta ggtgggatta
     2341 ttggtgcagt cagtgagcat ctgacctttg atgtttatta tcaaactgcc ctagagattg
     2401 ccttaggggc aagtagccag catatcatcg tagaagatga agagtcggca accaaagcta
     2461 ttgatttcct taaacgaaac agagccggtc gtgcaacctt ccttccgttg acaacaatca
     2521 aggctcgtac gatttctagc cagaatcaag atgctatcgc tgtaagtcca ggtttccttg
     2581 ggatggcaga tgagttggtg acttttgata ctagactgga agccattttc aagaacttgc
     2641 tagctacgac ggctatcttt gataccgtag aacatgcgcg tgcagcagct cgccaagttc
     2701 gttatcaggt tcgtatggtg acattggatg ggacagagtt gcgcacaggt ggttcttatg
     2761 caggtggtgc caatcgccag aataacagca tttttatcaa gccagaactg gagcaattac
     2821 aaaaagaaat tgctgaagaa gaagcaagct tgggttcaga agaggcgact ttgaagacct
     2881 tgcaagatga gatggccaga ttgaccgagt cattagaagc tattaaattt caaggagagc
     2941 aggcacgtat tcaggagcaa ggcttgttcc tcgcttatca gcaaactagt cagcaagttg
     3001 aagaactgga aactctttgg aaactccaag aagaggaaat agatcgtctt tccgagggag
     3061 attggcaagc ggataaggaa aactgccaag agcgccttgc tacaatcgcc agagacaagc
     3121 aaaatctgga agctgagatt gaagagatta agtccaacaa aaatgccatc caagaacgct
     3181 atcagaactt gcaagaacag gtagcgcaag ctcgtttgct taagacagaa ctgcaagggc
     3241 aaaaacgtta tgaagttgct gatattgagc gtttaggcaa ggaattggat aatctggata
     3301 tcgaacaaga ggaaatccag cgccttcttc aagaaaaggt tgacaatctt gagaaagttg
     3361 atacagaatt gctcagtcaa caggcggaag aagccaaaat gcagaaaaca aacctccaac
     3421 aaggtttgat tcgcaagcag tttgagttgg atgatattga aggtcaactg gatgatattg
     3481 ctagtcattt ggatcaggct cgccaacaga atgaagagtg gattcgcaag caaacacgtg
     3541 ctgaagccaa gaaagaaaag gtcagcgagc gcttgcgcta tttacaaagt caattaacag
     3601 accaatatca gattagctat actgaagctc tagaaaaggc gcatgaattg gaaaacctca
     3661 atctggcaga gcaagaggtg caggatttag agaaagctat tcgctcactg gggcctgtca
     3721 atatagaagc tattgaccag tacgaagaag ttcacaatcg tctggatttc ctaaatagcc
     3781 aacgagatga tattttgtca gcgaaaaatc tgctccttga gaccattaca gagatgaatg
     3841 atgaggtcaa agatcgcttt aaatcaacct ttgaggccat tcgtgaatcc tttaaagtga
     3901 ccttcaaaca gatgtttgga ggaggtcagg cagacttaat cttgactgag ggagacttgt
     3961 tgacagctgg ggttgagatt tctgttcaac ctccaggtaa gaaaatccag tcgcttaacc
     4021 tcatgagtgg tggtgaaaaa gccttatcag ctcttgcttt gcttttttct atcattcgag
     4081 ttaagactat cccatttgtc atcttggatg aggtagaggc tgcgctggac gaagccaatg
     4141 ttaaacgttt tggggattac ctcaaccgct ttgacaagga cagccagttc atcgtcgtaa
     4201 cccatcgtaa gggaaccatg gcagcggctg attctatcta tggagtgacc atgcaagaat
     4261 cgggggtctc aaaaattgtt tcggttaagt taaaagattt agaaagtatt gaaggatgac
     4321 aattaaacta gtagcaacgg atatggacgg aaccttccta gatgggagtg ggcgctttga
     4381 tatggatcgt ctcaagtctc tcttggcttc ctacaaggaa aaagggattt actttgcggt
     4441 ggcttcgggt cggggatttc tgtctctgga aaaattattt gctggtgttc gtgatgacat
     4501 tattttcatc gcggaaaatg gcagtttggt agagtatcaa ggtcaggact tgtatgaagc
     4561 gactatgtct cgtgactttt atctggcaac ttttgaaaag ctgaaaacgt caccttatgt
     4621 agatatcaat aaactgctct tgacgggtaa gaagggttct tatgtgctag atacggttga
     4681 tgagacctat ttgaaagtga gtcagcacta taatgaaaat atccaaaaag tagcgagttt
     4741 ggaagatatc acagatgaca ttttcaaatt tacaaccaac ttcacagaag aaactcttga
     4801 agctggggaa gcttgggtaa acgaacatgt tcctggtgtt aaggccatga caactggctt
     4861 tgaatccatt gatattgttc tggactatgt tgataagggt gtggctattg ttgaattagc
     4921 taaaaaactt ggtatcacaa tggatcaggt catggctttt ggagacaatc ttaatgactt
     4981 acatatgatg caggttgtgg gacatcctgt agctcctgaa aatgcacgac ctgaaatttt
     5041 agaattagca aagactgtga ttggtcacca taaggaccag tcggttatag cttatatgga
     5101 gggcttataa tggcagatat aaaattaatc gcattggact tggacggtac cttgctgact
     5161 actgataaaa ggctgacgga tcgcaccaag gcaactttga aagctgcgcg tgatcgtggt
     5221 atcaaggtcg tattgacaac tggtcgtccc ttaaaagcca tggatttctt tctccatgag
     5281 ctaggaactg acgaccacga agatgagtat acgattactt ttaatggtgg tttagttcag
     5341 aaaaatacag gagaaatcct tgataaaaca gtcttttcat atgatgatgt ggcacgtttg
     5401 tatgaagaaa cagagaaatt atcactgcct cttgacgcta tctcagaagg aactgtttat
     5461 caaattcaat cggaccaaga aagtctttat accaaattca atccagcctt gacctttgtt
     5521 ccagtggact ttgaagactt atctagtcaa atgacctaca acaaatgcgt gactgccttt
     5581 gctcaagaac ccttggatgc agccattcag aagatttctc cagaattgtt tgaccaatat
     5641 gaaatcttta aatcacgtga aatgttgcta gaatggtcac caaataatgt tcataaagca
     5701 acaggtttgg caaaactaat cagtcatctt ggaatcgacc aaagccaagt gatggcttgt
     5761 ggtgacgagg ccaatgacct ctctatgatt gaatgggcag gtctcggtgt tgccatgcaa
     5821 aacgctgttc ctgaagtcaa ggcagtcgca aatgtggtaa ctcctatgac caatgatgaa
     5881 gaagctgtcg cctgggctat cgaagaatat gtgctaaagg agaactaaga tatgggatta
     5941 tttgaccgtc tattcggaaa aaaagaagaa cctaaaatcg aagaagttgt aaaagaagct
     6001 ctggaaaatc ttgatttgtc tgaagatatt gagcctgcct tcacagaagc tgaggaagtt
     6061 tctcaagaag aagcagaggt tgaaagttct gaagaatctg tgttccaaga agaggatagt
     6121 caagacacag tcgaagaaaa tctggattta gagccagttg tagaggtttc tcaagaagaa
     6181 gtagaagaat ttccaaactc acaagaagtc acagaggaag agaagcttga gcacgaagga
     6241 actatagaag aaaataattc tgaagttctt gaaccagaaa ctcctcaaac agaagaaact
     6301 gttcaggaaa aatatgaccg cagtcttaag aaaactcgca caggtttcgg tgcccgcttg
     6361 aatgccttct ttgctaactt ccgctctgtt gacgaagaat ttttcgagga actggaagaa
     6421 ctgctgatta tgagtgatgt tggtgtccaa gtcgcttcta acttaacgga ggaactacgt
     6481 tacgaagcca agcttgaaaa tgcgaagaaa cctgatgcac ttcgtcgtgt catcattgag
     6541 aaattggttg agctttatga aaaggatggt agctacgatg aaagcatcca cttccaagat
     6601 aacttgacag ttatgctctt tgttggtgtg aatggtgttg ggaaaacaac ttctatcgga
     6661 aaactagccc accgctacaa acgagctggt aagaaggtca tgctggttgc agcagatacc
     6721 ttccgtgcgg gtgcagtagc tcagctagct gaatggggcc gacgagtaga tgttccagta
     6781 gtaactggac ctgaaaaagc tgatccagcc agcgtggtct ttgatggtat ggaacgtgcc
     6841 gtggctgaag gtatcgatat tctcatgatt gatactgctg gtcgtctgca aaataaggat
     6901 aaccttatgg ctgagttgga aaagattggt cgtattatca aacgtgttgt gacagaagca
     6961 ccacatgaaa ccttcttggc acttgatgca tcaacaggtc aaaatgccct agtacaggcc
     7021 aaagaatttt cgaaaatcac acctttaacc ggaattgttt tgactaagat tgatggaact
     7081 gctcgaggag gtgtggttct agccattcgt gaagaactca atattcctgt aaaattgatt
     7141 ggttttggtg aaaaaatcga tgatattgga gagtttaact cagaaaactt tatgaaaggt
     7201 ctcttggaag gtttaatcta atcagaagca aaaatcctgc aaggcataaa cttgcaggaa
     7261 atttttttat tcgaaacgac catcttgacg ataggcgata tccggttgcc aagtccattt
     7321 ggcaccgaat ttttcaagta ggtcaaagct ggcttgaggt cccatgcttc cagctttata
     7381 gtcatgaagt ggggcaccat tttcagccca gagcttttca atacggtcaa tcaacttcca
     7441 tgacgcacca acttcatccc agtggctaaa gttagttgag ttgttattta ggacatcata
     7501 aatcaatttt tcgtatggtt ctggagaagc accagttgca gtcgcatctg tacggtaatc
     7561 aagtgagtta ggagccaagt taaattcttc tcctacttgc ttcccattta ggctaagaga
     7621 gaagccttct gttggttgaa tatagatagt caaaatattt ggagcaagtg gttctccaaa
     7681 gatagaatcc atttgtttaa agacgatgtt gacatgagtt cctttttcag tcagtcgttt
     7741 acctgtacgg aaaaagaaag gaacactacg gaatcgatcg ctgtctacaa agaaggcacc
     7801 agatgtaaag gtttcagttg ttgattctgg attcacattt ggctcgctac gataagagat
     7861 gtatttcatg ccatcaatct taccagagcg gtattgccca cggataaagt gttctttgag
     7921 ttcttcatca gttggatgat agaggttttt aaagacctta atcttttcag cacgaatctc
     7981 gtcttttgtg aagcttgctg gtttgtccat ggcgaggagc gaaagaagtt gtagagtgtg
     8041 gttttggacc atgtcacgga gggcaccgga ttggtcatag tagccaccac gttcttctac
     8101 acccaagcgc tccgcaaagg taatttgaac attgtcgata aaatccttgt tccaaacgtt
     8161 ttcaaaaatc aagtttgcaa agcgaactgc aaagatgctt tggatcattt ccttaccaag
     8221 ataatggtcg atacggaaaa tttgttcttc gtcaaatgtt gctaggagtt cgtcattcaa
     8281 cttgcttgca gttgcgtaat ctgtaccaaa tggtttttca acgatcaagc gctcaaaacc
     8341 tttgccatcg acaatgtttt cagatttgag gtgtttggca atggttccaa agaactgagg
     8401 tgccatagac aagaagaaga acttattgtg ttcagcttgg tatttttcat taagctcagc
     8461 ttgtaattga cgcaaagcaa tataatgttc cgaatcattg acatcatggc tttgatagta
     8521 gaagtggcta gcaaattctt gggcttgctc ggtactatct gccaaatcaa ggatggactc
     8581 gacaactaca gattcaaaat attccttact ccaaggtcta cgggcagttc caataacggc
     8641 aaagtgcttg gaaagattgc cggatttata taatctaaaa agggaagggt agagcttgcg
     8701 tttagccagg tctccactcg caccgaaaat tgtaacaata accttagatg acatctagct
     8761 acctaatttc tatttttatt cctagtcttg ctaggtatga ggaaacctca tttcataaac
     8821 ttaattctaa cataattttc cgaaaaatca aaaattccaa tacgaggtag aaaaactgca
     8881 aggaaatcct tacagtttga gtttagacgt ttaagacctt atctaagaac tctttcagac
     8941 gagggtgttg tgggttatca aagatttggt caggtgttcc gtcttcaagg aactcgccat
     9001 ctgcagtaaa gataacgcgg ttggcaacct gacgagcaaa tcccatctca tgggttacga
     9061 taatcatggt catgccttgc tcagccaatt ccttcataac gttaagtacg tctccaacca
     9121 tctcagggtc aagggcagaa gttggttcat cgaagagcat gatgtctgga ttcattgcta
     9181 ggccacgagc tatggccaca cgttgttttt gaccacctga taggctatct ggattggcat
     9241 tagctttatc tgctagtcca accttttcaa gcaactccat tcccaatttc tcagcttctt
     9301 ccttagtcat caacttgtgc tcaataggag caaaggtgat gttgtccaat acagacatat
     9361 gagggaagag gttgaagtgt tggaatacca tgccgatatt ttcacggacg tggtcaacat
     9421 tggttgtttt ttcagttaaa tcatagccgt tcacagtgat gtgaccgcta gtgacttctt
     9481 ctaaaagatt gaggctacgg aggaaagttg acttaccaga acctgaagga ccgatgatac
     9541 aaacaacatc tccttcatag aacttagtcg taattccttt taggacttca ttttttccat
     9601 agtgcttgtg taaatcattt acatcaattt ttaattttgc cattaacgaa tcctcttttc
     9661 taagcgtttc gctagtctag tcaaaagtgt gataattaca agatagaaga tagcaaggat
     9721 tgcatacatc ttgaaacttt ggtagttacg agcaatgata atcttaccag tttggaagag
     9781 ttcaaccaaa ccgatagcag atacgatagt tgtatcttta agagcgataa cgaattggtt
     9841 gacaaagttt ggcaacatca atttagttgc ttgtggcaag ataatcttac gcatggtttt
     9901 tccataagag atacccaagc ttcggctggc ttccatttgg ccaactggaa cggcctgaat
     9961 accaccacga acgatttcag cgatataagc agccgcattg agtgagaggg caatggttcc
    10021 agctacaaag tcgttaattg ggctttgttg gcctgtgata gactcgatga agtttggaat
    10081 cccccagaag atgaaggctg caagaatcat caatggaata ccacgaataa cgtcaacgaa
    10141 aatctcagag atgactcgaa gagatttgta tgggctaacg ctaaacatac cgaagataat
    10201 tccgatgaca atggcaatag caaatgagat aagagctaga gcaagagtga taccaagacc
    10261 gctaaggagt tgtttgtagt tgttttgaag caagccccag agcgttgttt cgtcaacagt
    10321 acttgttgaa gcagttgaag attcgctagc taggtatttg tcaagaatct tttggaattc
    10381 accgtttgct ttaaggtttg caagtccgtt gttgaacatt tcaatcagtt ctggatttgc
    10441 tcctttttta acggcaaagg ctgtttcacc gattggagtt ccagagattg gagttttcaa
    10501 tttttgacct tggctgatag aatatttgag aacaggttca tcatccataa cagcatcaat
    10561 ggcaccagtg tttaaactgt catacattga tgaaccatca gcgaaggttt taatttgata
    10621 accgtatttg ctttgatttt ctgttaggaa ggtttgagaa gcagttccgt ttttaacacc
    10681 gactgtcttt ccttttagat cttcataaga agcaatattg cttgattctt tgacaccaag
    10741 aatggtatta gcagtgtagt atgattctga gaagtcaaaa gttgccttac gagcatctgt
    10801 gacagacata ccagcaatga taccatcggc ttgaccagct tggacagcac tgatagcagc
    10861 atcaaaacca gggttggtga tttcaatttc aaaaccttgg tctttagcga ttgccttaat
    10921 caattccata tcaataccag tgtattggtt gcttgaattt tggaaaacaa aaggtgcaaa
    10981 agaagaatcg ctggcaatga tatatttagc cttaacagga atagctttta atcctgctag
    11041 agtagttgta gttggcactg ctgaagatga tgaagcagtc catttcttga taattttatc
    11101 aagactacca tcttttttca tttcagccaa ggcttggtta aattcagtaa ccaggtgctc
    11161 gtatttactt ccttttttca caccgaaagc aaaacttcct acagcttcac catccatttc
    11221 aatatggagg tcttgacctt ggttaatggc atattcgata acaggtttgt catccatcat
    11281 ggcatcgatg gcaccagcac tcaagctgtt attcattaaa tcaccagtgt caaatgtttt
    11341 aatagtaaag ccgtatttat ctttgattgt ttcaaggaaa cgttgagcgg cagttccgtt
    11401 tttaacacca acggttttgc cagttaattg gtcgtacttg ctaattttgt gtgactttgt
    11461 agtagcaatg acaacttttg tatcatagta agtatcagac atggtgaaga ctttttcacg
    11521 ttctttagtc tttgtcatcc ctgccatgat agcgtcggct tgcccagctt gaaccgcatt
    11581 gactgctgcg tcaaatccag gataggacat ctgaatgttc cagcctttaa tctcagcgac
    11641 tttgttaata atgtcaacat caattccttt ataagtttga tctgaatctt taaactcaaa
    11701 aggtgcatag gcggtatcag aaacaatctt aatcgtttct gctttggcaa tacctagtga
    11761 gaaaattggg aataaaatta gcaaaaatgc tagaaatttt ttcttcattt ttagtctcct
    11821 tttccgaata ttctctcatt atatcagaaa aagtaaaaaa aggcaaattt ttatattttt
    11881 cgtgtcagaa aatataacat tgatttttcc ttttctttct tgaattgcta ttaaaaagtg
    11941 ctataataat agtgtatata gaagaaaaga ggacggggat atgaagaaca aaagaatatt
    12001 taaagacttc caagcttcaa aaatgagttt aaacatttac acaagcccct tgttagcctt
    12061 tgtttttgtc ttcataggag agtttgtggc ttatacttta tatggtatta gtttgttagc
    12121 tctcatcgga cttgctagaa attttggaga ggccggtcaa aatcttgcaa gctacttgca
    12181 gaccttgcat cagagcttga cggataaaac aagtgatttt cgtttaattt taggattact
    12241 ggcctttggt tttattctta acactgtgtt cagatggaca agaaaagttg agaaaagacc
    12301 tattcgaacc ttgggatttt atagagagaa ttgcctcagc aatcttctga aaggatttag
    12361 tctaggcctg gcactttttc ttctgacctt gttaggttta gtggtcttag gtcaatatcg
    12421 tttggaatcc attcacttga atccttattc tcttgccttt gtcgtcttta ctatcccatt
    12481 ttggatttta caggggacag cagaagaagt ggtggcccgt gcttggctac ttcctcaatt
    12541 ggcctcaaga accaatctaa aacttactat tcttatatct agcgtacttt ttactctgct
    12601 tcatgtgggg aatgcaggtc tcacccctct atctctagta aatctctttt tattcggagt
    12661 tgccatggct ctttaccttc tcaaaattga tacagtttgg ggtgttgcag gtattcatgg
    12721 tgcttggaat tttgctcagg gtaatctctt tgggatttta gttagtggtc aaccgtcagg
    12781 aacgtctctg atgacctttt taccacaagg caatcaagat tggctatcag gtggttcttt
    12841 tggcatagaa ggttccatta tgacaagtct ggtattacta ctgctgattg tctatcttgc
    12901 taataaatta aagaaagaaa atgaaaggat gtgacttcgg tccgtccttt tcttcgtgaa
    12961 aatactataa gtatgctaaa ataggaatag cacatggaga gaggattctt atgatcaatc
    13021 acattacaga taatcaattt aaactagtat caaaatatca accatcagga gatcaacccc
    13081 aagctatcga gcagttggtg gataacattg aggggggaga aaaagctcag attctgatgg
    13141 gggcgactgg aacagggaag acctatacta tgagtcaggt catttctaaa gtcaataaac
    13201 caactctggt tattgcccac aataaaactc tggctggtca gctctatggg gagtttaagg
    13261 aatttttccc tgaaaatgca gttgagtatt tcgtatccta ctatgattat taccagccag
    13321 aggcctatgt cccttctagc gatacctata ttgagaagga tagttctgtc aatgacgaga
    13381 ttgacaagct tcgccactca gctacctcag cccttttgga gcgtaatgat gttattgtcg
    13441 tggcctcagt ctcttgtatc tatggtttgg gttcgcccaa ggaatacgct gatagtgtcg
    13501 ttagtctccg tcctggtcta gagatttctc gtgataaact cttgaatgac ttggtcgata
    13561 ttcagtttga acgtaatgat attgatttcc aacgcggaag atttcgcgtt cgtggggatg
    13621 tggtagagat tttcccagct tcccgagatg aacatgcctt tcgagtagaa ttttttggag
    13681 acgaaattga ccgtattcgt gaagttgagg ctctgacagg tcaggtgttg ggagaagtgg
    13741 atcatttagc gattttccca gcgacacact ttgtgaccaa tgacgaccac atggaagttg
    13801 ccattgcaaa gattcaggcc gagttggagg agcagttagc tgtctttgaa aaggaaggta
    13861 aactgcttga agcccagcgt ttgaaacagc ggacagagta tgatatcgaa atgttgcgtg
    13921 agatgggcta taccaatggg gttgaaaatt attctcgcca catggatgga cggagcgaag
    13981 gagagcctcc ttatacgctt ctcgacttct tcccagatga tttcttgatt atgattgacg
    14041 agagtcatat gaccataggg caaatcaagg gcatgtacaa tggagaccgt tcgcgtaaag
    14101 aaatgctggt taattatggt ttccgtttgc cgtctgcttt ggacaatcgt cctctccgtc
    14161 gggaggagtt tgagagtcac gttcatcaga ttgtttacgt ttcagcgaca cctggtgact
    14221 atgaaaatga acagaccgag acagtgattg agcaaatcat tcgtccaacg ggactcttgg
    14281 atccagaggt ggaagtccgt ccgactatgg gacagattga tgacctcttg ggtgaaatca
    14341 atgcccgcgt tgaaaaaaat gagcgtacct ttatcacaac tttgaccaag aaaatggcag
    14401 aggacttgac cgactacttc aaggaaatgg gtatcaaggt caagtacatg cactcggata
    14461 tcaagacctt ggaacggacg gagattatcc gtgacctgcg cttgggtgtc tttgatgtct
    14521 tggtcggaat taacctgctc cgtgaaggaa ttgacgttcc tgaagtgagc ctcgtagcta
    14581 ttctcgatgc tgacaaggaa ggtttccttc gcaacgaacg tggactcatc cagactattg
    14641 gacgtgctgc tcgtaacagt gaaggccatg tcatcatgta tgcagacacg gttacccagt
    14701 ctatgcaacg tgctatcgat gaaactgccc gccgtcggaa aattcagatg gcctataatg
    14761 aagagcatgg tatcgtacca cagacaatca agaaagaaat ccgtgacctg attgccgtga
    14821 ccaaggcagt tgctaaggaa gaggacaagg aagtcgacat caatagcctc aacaaacaag
    14881 agcgcaaaga actcgtcaag aaactagaaa aacaaatgca agaagccgtc gaagtgcttg
    14941 actttgaact ggcggctcag atccgtgata tgatgttgga agtcaaggcc ttggattagg
    15001 ggaatagtat gatttattta agaaagttaa agagagaaga tttgatgtct ttatgggaaa
    15061 tggcttattc acaacttaat ccagtttgga aacagtatga tgctccctat tatgatgatt
    15121 atcagtattt ttcaaatttt aaagaattcg aactacaaaa atcagaatcc attttaagca
    15181 actcaaatcg ccttggtatt tttgttgatg ataaactagt tgggactgtt tcgcgttatt
    15241 gggtatgtaa acaaacaaga tggatggaat tgggaattgg tatttatgat aaaaaattct
    15301 ggaacactgg tattgggaaa gttgctatgt tgcagtggat agataggacg tttcaggatt
    15361 acttggagtt ggagcatctg ggtttgacaa cttggtcagg gaatcttggt atgatgaaac
    15421 ttgctgaaaa attaagaatg aaaaaagaag ctcatattcc aaaagttcgt tattatcaag
    15481 gtaaatattt tgatagtatt aaatatggta ttttgagaga agactgggag aaaataaatg
    15541 acggttatta tcaaatcaat ggaaactcct aaagagatag aaggtaaatc ccttgttcac
    15601 tggcaaatgt ggagagaggc ttatgatgac cttttgcctg cagaatttca ggagacaatg
    15661 acattagaaa gatgtcgact ctttagtcaa aagtatccag aaaatacatt gattgcgata
    15721 ggtgatctga aggtagttgg ttttatcagt tatggtaact ttcgtgatga gactatgcaa
    15781 gctggtgaaa ttattgcttt atatgtttta aaagactatt acggaaaagg cattgcacaa
    15841 aagttaatga aagcagcttt gactgctctg aatcattttt ctgaaatttt cttatgggta
    15901 ttgaaagata acaagcgagc cattgctttc tatcaaaaaa tgggttttac ttttgatgga
    15961 caagaaaaga tacttgaact tggaaagcct ataaaggaaa aacgaatggt attctattct
    16021 aaaataattt taaaaagtag aagctaatgg cactggtacc aagtctgaaa atttaataaa
    16081 ttagaaagcg agtaaattta tgtcccgttc ccaattaacg attttaacca atatttgtct
    16141 gattgaagac ttagaaactc agcgcgtagt catgcagtat cgctctcctg acaccaatcg
    16201 ctggtcaggt tatgcctttc ctggaggtca tgtagaaaat gatgaggctt ttgcggagtc
    16261 tgtcattcgt gaaatctacg aagaaacagg gttgactatc caaaatcctc aacttgtcgg
    16321 cattaaaaat tggccactag atacaggtgg gcgctacatt gttatttgtt ataaggcgac
    16381 tgagttctct ggtacccttc gctcttcaga agagggagaa gtttcttggg tgcaaaaaga
    16441 ccagattcca aacttggatc tggcctatga tatgctacct ctgatggaga tgatggaagc
    16501 tccggacaaa tcagagtttt tctaccgtca tcgtacagaa gacgattggg aaaagaaaat
    16561 tttctaatcc tttactaaat aaccgagctg ctccaaggcc tcctcgatat agtggaggtc
    16621 ttgttgtgtt tcggcttcga ctaggtggta atggatgcca tctgtcaatt cagatagagg
    16681 tctaaagtca gaatgctcga cttgttctag aaaatgttgc acatctctgc gacaagacag
    16741 tttaagcaag gtttcaattt ctccataaac gggatggtca atcaaggtat tctggacatg
    16801 cccaccatta tcgacaatag caaggagttc ctgaccgatt tcttcaactt catgtttcac
    16861 tttgaaaagt ttgtgaacat aaggattggt atcaatttgc ttatagatgt agccacgatt
    16921 ggtggatagg ataggagcgc catcggctct caaaattgca atgtcctgca caatgacctg
    16981 acgtgtgaca tgaaaatgtt ccgccaaact ttggccatta agggctttag gagcttcttt
    17041 caagagttgg agcagggctt gtttgcgatc ttttgtcata gcttttcctt ttaacggcgt
    17101 tttcgaagca ctttatagac agctagtgct aatgtatagt ctaccatact atggataatt
    17161 gtgccaaatc caactagcac aaatagaaca tagaacatgt tttctacatt ggtacccgaa
    17221 gttgcgtaaa aaaggacaca ggctaatact tcagcaaggg catgaacaac agccaaaaca
    17281 aagttgaaaa cccaggaaga ttttggttta tctagggtat cggggaattt ttgtaggtaa
    17341 agagctccta aagcaccaaa agatatatgg gaaaaagccc gaaaaacgat aaccatggga
    17401 tagccagcca tcaaaaatcc aaaactagag gctaggatga caaaaactgc catcaagggc
    17461 gacaagaaca tggctataaa aatagcgatg tggctcccca aagtatagga agcaggtgga
    17521 atgacaatct tgaaaggcat aacaattgga atcaaaatcg caatagccgt taaaagggct
    17581 gtcattgtca taaattgtgt ctttttccgt gtattcacaa gaatctcctt tttaactgca
    17641 tatacactag tatggtacaa taaaccagac aataaagcaa gaatttactt gggtttatag
    17701 atcatttttt agttaaaagt tatagtagat tgaaactaga atagtccacc tctacttcta
    17761 aaacattgtt agaaatcgat ttggctgtcc tgatcaattt gtcctgttct tatttcgttt
    17821 tactatagta aagatttcat taaaaagaaa ctgtatagag caaaatctcc accttcaggt
    17881 ttgaaagcgg agattgtttt tattttttca aggtttgtag tcgtggaaca atggctaggg
    17941 ttagaattgc agaaatgacc aattcagcaa ttgaatttgt tgagataacg gttgccagaa
    18001 gaagttggat atttccgtta taaacatttc caaataggaa gaagattcct ccaaggacaa
    18061 agatagtatt tgtcaaggaa ccaagagccc cagctaaaat cagaccagtc ttgtttttca
    18121 tcagtttata gactaagtaa ggagttaaac caatcaaaat acgtgggaca atggcaatga
    18181 tagctgagta gatgtttccg tttggtacga agggagagaa gaggtagctt gtcggtagaa
    18241 tcgtaatcgt gttaaccgtc aagctaagta atcccatcaa aaatccaagt gtaaccccaa
    18301 ctcgtggacc ataaataatg ctggcaataa tgacaggaat atgaacaatg gtcggtttga
    18361 ttggaaatgg aaaaaggtta aagataagtg agctcagaaa gtgtatcacg agcatggtag
    18421 caaaaaagat agcaatgggt gcaatattag agcgtttttt catcgatagt ttcctttatt
    18481 ctttctaaaa taattgtgag gtcagctaaa gctcctcgtc cgtggtctcc acaagctagt
    18541 agggattcct taggagcaat cagctgatag ccgtaggttt ctaatgtttt cagattattc
    18601 tgagttactg gatggtcata catttttgta ttcatagcag gagctattag tttgggaata
    18661 tgacttggta gggctagagc tgtactggtt accatgttgt ccgcaaatcc gtgagctagt
    18721 tttgcaatag tgttagcagt tgcaggtacc acgataaata aatctgcttt ttttccaagt
    18781 tcgatatgat tgacctgatc aggatagggt tctttcatga catccaagtg gacaggattc
    18841 tgtgagagta cctgtagtgt caaaggttgg ataaactctg tagcagcctg agtcattaag
    18901 acagtgactt gatggccttg tttttttaga gaactgacta aatctgccga cttataagag
    18961 gcgattgaac ccgttacagc caagagaatg tttgccatag ttttcctttc taagaatgat
    19021 aggcttgaat tttttcaagg aggagttctg caatttcttc tttagtctgg actgtttgaa
    19081 gctgattttt ctcaacaaat atagctcggt gctgatctgc tgaaatttga gtcaggtcat
    19141 tcgcgatgat taaatctgct tgattcttga taagactttt tcgtgcaatg tcaaccagat
    19201 gatcttcggt aacatcaacc agcagtttga aaccaatcag atgaatagta ggattccatt
    19261 ccttgactag ggatatgatt ttgggtgtct ttttaaggaa caaaacctga acctcatcag
    19321 ttgaagaaat cttggcctga tgattctgct tgcttaaaaa ttcttttaga ttggagctag
    19381 cctgaacttc ctcaagccct gtcatataaa caggagtgta gtcagaaaca gccattgagt
    19441 ggatcaagac ctgataatcc tgaacacgtt cttgtatttc tattagaagg tccttggtat
    19501 tggtaatttc tcgaatactt aggttaggat gaggctctgg cttcagagct cgttttgtcg
    19561 taattaaaca aacttcatgc cctgcagaaa gcaaagtctc tgtgataatt ttccccaagt
    19621 gacctgtaga atggttagtg atagagcgga cgctatcgat agcttcactg gtaccgccca
    19681 atgtaactaa aattttcata gcactattgt acacaaaaat aagcggtaag taaaatgaaa
    19741 gtgataaatt tttggtaaaa acgaagattt actatagttt caaactataa agccatataa
    19801 aatttaagaa aggactctaa aagccttaaa aaacagagat atttacgaac gtttagagag
    19861 ttttagggtg ttaaaaatct tgttttgtga tataatgaat tatcatataa gaggttagag
    19921 gaattttgaa tgaaaacaga tattgaaatc gcacagagta ttgagttgaa gccaattgtt
    19981 gatgttgtag agaaacttgg tatttcttac gacgatttgg agttgtacgg aaagtacaag
    20041 gctaaactca gctttgataa aattcgtgca gttgagagca atccagtcgg taaattgatc
    20101 ttggttactg ccatcaaccc aacacctgca ggtgaaggaa agtcgacgct taccattggt
    20161 cttgcggatg ccttgaacaa gattggcaag aaaaccatga ttgctatccg cgaaccgtct
    20221 cttggtccag tcatggggat caagggtggt gctgctggcg gtgggtatgc acaagttctg
    20281 ccaatggaag acatcaacct ccactttact ggagatatgc atgctattac aactgccaac
    20341 aatgcccttt ctgccttgat tgacaaccac ttgcaccaag ggaatgagct gggaattgat
    20401 caacgtcgta tcctctggaa acgcgctgtg gacttgaacg accgtgcgct ccgccatgtg
    20461 actgttggtc ttggtggtcc tctaaacggt attccacgtg aggatggttt tgatattaca
    20521 gttgcttcag aaatcatggc aattctttgc ttggcaacgg acatcgagga cttgaaacgt
    20581 cgtttggcga atatcgttat tggttatcgc tatgaccgta cgcctgtttc tgtaggtgat
    20641 ttgcaggttg agggtgcctt ggctttgatt ttgaaggatg ctattaagcc aaacttggtt
    20701 cagacaattt acggtacacc tgcctttgta cacggtggtc catttgccaa tatcgctcat
    20761 ggatgtaact ctgttttggc gacgacaaca gcccttcact tggctgatta cactgttact
    20821 gaagctggtt ttggtgcgga ccttggtgct gagaaattcc ttgatatcaa gacaccaaac
    20881 ttgccaacat ctccagatgc agttgttatt gtcgcaaccc ttcgtgccct taagatgaat
    20941 ggtggtgtga ctaaagacgc tctgactgaa gaaaatgtag aggcagttcg tgcaggtttt
    21001 gctaacttga aacgccacgt tgaaaatatc cgtaagttcg gtattccagc agttgtagct
    21061 attaacgaat ttgtatctga tacagaagct gaaattgcag tcttaaaaga actctgtgcc
    21121 tcaatcgatg taccagttga attggctagt gtctgggctg atggagcaga aggtggagta
    21181 gcacttgccg aaacagttgt taagacaatt gctgaaaatc cagctaacta taaacgtttg
    21241 tatgataatg acctttctgt ccaagaaaag attgaaaaaa ttgtcactga aatctatcgt
    21301 ggtagcaaag tgaactttga gaagaaagct caaacacaaa ttgctcaaat cgttcaaaac
    21361 ggttgggaca aattgccaat ctgtatggct aaaactcaat acagtttctc agacaatcca
    21421 aatgcgcttg gagcaccaga aaactttgaa attaccattc gtgaattggt accaaaatta
    21481 ggtgcaggct tcatcgttgc cttaactggt gatgttatga ccatgccagg tcttccaaaa
    21541 cgtccagcag ctctcaacat ggatgttgaa agcgatggaa ctgtactagg cttgttctag
    21601 tggattgaaa ttgactttaa gtgagtttgg aaataatatc caagctcatt ttttctcaga
    21661 ctgcaagcag ttcatcaata agatttatac tcttcgaaaa tctcttcaaa ctatgtcagc
    21721 ttcaccttgc cgtaggtata tgatactgac tctgtcagtt ctatccacaa ccttaaaaca
    21781 gtgttttgag caacctgcgg ctagcttcct aatttgctct ttgattttca ttgagtataa
    21841 gtagatagaa aagttatata ctatctattg aaaatattat aaatcagata caaagacagg
    21901 tgaaaccttc tgtgttatac tagagatatg ttagatttga aagaatacgg tatcgtcatg
    21961 tggccggagg agaaagtcat ttctttccgt gagaaacttc tcgcttggta tgatgaaaac
    22021 aaaagagatt tgccttggag gagaagtaaa aatccttatc acatctgggt atctgaaatc
    22081 atgcttcagc agaccagggt ggatacagtt atcccttact acgaaagatt cctggactgg
    22141 tttccaactg tcgaaagtct ggcaactgcg cctgaggaga gtttactgaa agcttgggag
    22201 ggcttgggct attattctcg agttcgcaat atgcaggctg cagcccagca gattatgact
    22261 gactttggtg gccaatttcc aaatacctac gaaggaattt ccagcttgaa agggattgga
    22321 ccttacacag caggagccat ttccagtatt gcttttaact tgcctgagcc agctgtagat
    22381 ggtaatgtca tgcgggtctt ggcgcgtctg tttgaagtca accacgatat tgggattcca
    22441 agtaatcgaa aaatttttca ggcaatgatg gagatcttga ttaatccgga tcgtccgggt
    22501 gattttaatc aagccttgat ggacttaggg tctgatattg agtctcctgt aaatcccaga
    22561 cctgaagaaa gcccagtcaa ggactttagt gcggcatatc agaatggaac catggaccgt
    22621 tatccaatta aatctcctaa gaaaaagccg gttcctattt atcttaaagc cttagttgtg
    22681 aaaaattctc aaggacaatt tttacttgaa aaaaatgaaa gcgaaaagct cttggcaggt
    22741 ttttggcatt tcccctttat agaagttgat aacttttcgc aagaagagca gtttgacctc
    22801 tttcatcagg ttgcggaaga aagtgtgaac tttggtccca gtccagaaga gagtttccag
    22861 caggactatg acctagatgt tgattggctt gatgtttgtt ttgatacagt ccagcatgtt
    22921 tttagtcatc gaaaatggca tgtacagatt gtagcaggtc aggtgagtga cttccatgat
    22981 ttttcagata gggaagttcg ctggctttca ccagaagaat tcaagaatta cccacttgcc
    23041 aaaccccaac aaaaaatctg gcaggcttat gcacaagcca acttagacag tagccaagac
    23101 tagctattgt gtcttctgac tatttttttg gtataatagt agagaaaaag gtgaacatat
    23161 gaaaaaaata ctaattgtag atgatgagaa accaatctcg gatattatca agtttaatat
    23221 gaccaaggaa ggttacgaag ttgtaactgc ttttaatggt cgtgaagcgc tagagcaatt
    23281 tgaagcagag caaccagata ttattattct ggatttgatg cttccagaaa ttgatggttt
    23341 agaagttgct aagaccattc gtaagacaag cagtgtgccc attcttatgc tttcagccaa
    23401 agatagtgaa tttgataagg ttatcggttt ggaacttggg gcagatgact atgtaacgaa
    23461 acccttctcc aatcgtgagt tgcaggcgcg tgttaaagct cttctgcgtc gttctcaacc
    23521 tatgccagta gatggtcagg aagcagatag taaacctcaa cctatccaaa ttggggattt
    23581 agaaattgtt ccagacgcct acgtggctaa aaaatatggc gaagaactag acttaaccca
    23641 tcgtgaattt gagcttttgt atcatttagc atcgcataca ggtcaagtca tcacgcgcga
    23701 acacttgctt gagactgtct ggggttatga ctattttggt gatgtccgta cagttgatgt
    23761 gactgtacga cgtctgcgtg agaagattga agatacgccc agccgaccag agtatatctt
    23821 gacacgccgt ggtgtagggt attacatgag aaataatgct tgatttactg aaacaaacca
    23881 tttttaccag agattttatc tttatcctga ttttgttagg tttcatcctt gttgtgaccc
    23941 tcttattact ggaaaataga cgtgataata ttcagttgaa gcaaatcaat caaaaggtta
    24001 aagatttgat tgcaggagat tattccaagg ttcttgatat gcaaggtggg tctgaaatca
    24061 ccaatattac caataatttg aatgacttgt cggaggttat tcgtctcact caggaaaatc
    24121 tagaacaaga gagtaagagg ctaaatagta ttctgtttta tatgacagat ggggttcttg
    24181 cgaccaaccg tcggggtcag attatcatga ttaacgatac agccaagaag caactggggt
    24241 tggttaagga agatgttctg aatagaagca ttttggaatt gctcaagata gaagaaaact
    24301 atgaattgcg tgatttgatt acccaaagtc cagaattgtt gctagattcc caagatatca
    24361 atggtgaata tttgaacctt cgagttcgct ttgccttgat acgtcgagag tctggcttta
    24421 tttcaggttt ggtggctgtt ttgcatgata cgacggagca ggagaaggaa gaacgcgaac
    24481 gaagactctt tgtttccaat gttagccatg agttacggac tcctctgact agcgtaaaat
    24541 cctatcttga agccttggat gagggggctt tgtgtgaaac tgtagcacca gactttatca
    24601 aggtttctct tgatgagacc aaccgtatga tgcgcatggt gacggatctc ctccatcttt
    24661 cacgtattga taatgctacc agtcacctag atgtggaact gattaacttc actgctttta
    24721 ttacctttat cctcaatcgt tttgacaaga tgaaaggaca ggaaaaggag aaaaaatatg
    24781 agttggtgag agattatccc atcaattcta tctggatgga aattgataca gataagatga
    24841 cgcaggttgt cgacaatatt ttaaataatg ctattaagta ttcgccagat gggggtaaaa
    24901 tcactgtcag aatgaagaca actgaagacc agatgatttt atccatttct gaccacggtt
    24961 tggggattcc taagcaggat ttaccacgta tctttgaccg tttctatcgt gtggatcgtg
    25021 ctagaagtcg tgcacaaggt ggtacaggtc taggactgtc tatcgctaaa gaaattatca
    25081 aacaacataa gggctttatt tgggccaaga gtgaatacgg caagggttca acctttacca
    25141 ttgtgctccc ttatgataag gatgcagtga aagaagaagt atgggaggat gaagtagaag
    25201 actagaatga gtgaaatagg ctttaaatac agtattttag cgtcgggttc cagtggaaat
    25261 tctttttatc tggaaacctc aaaaaagaag cttttagtag atgcaggctt gtctggcaag
    25321 aaaattacca gtctgctagc tgaaattaac cgtaagccag aagacctgga tgccatcttg
    25381 attacccatg agcattcaga tcatatccat ggagtaggcg ttttggctcg caagtatggt
    25441 atggatcttt atgccaatga aaagacctgg caagctatgg aaaatagtaa atatcttggc
    25501 aaggtgaatt cttcgcaaaa gcatattttt gaaatgggta aaaccaaaac ctttggagat
    25561 atcgacatcg agagttttgg tgtaagccat gatgcagtcg caccgcagtt ctatcgcttt
    25621 atgaaggatg ataagagttt tgtccttttg acagatacag gttatgtcag tgaccgtatg
    25681 gcgggcattg tcgaaaatgc ggatggctat cttatcgagg ccaaccatga tgtagagatt
    25741 ttgcgatcag gttcttacgc ttggcgactc aaacaacgaa tcctatctga ccttggtcac
    25801 ctttctaacg aggacggtgc tgaagctatg attcggacgc taggaaatcg tactaagaag
    25861 atttaccttg ggcatttatc taaggaaaat aatatcaagg aactggctca tatgaccatg
    25921 gtcaatcagc tggctcaagc tgatctggga gtcggagtag actttaaggt ttatgatacc
    25981 tcaccagata ccgcaacacc attgacagag atataaaaag aacgctgaga aggtgttctt
    26041 tttatattga ctgaacacat aaaaagtaat acaatggtgt taccattaaa aaagggagca
    26101 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
    26161 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
    26221 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
    26281 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
    26341 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
    26401 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagaccc
    26461 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
    26521 taattatcga gttatcgtac aaattgtaga tgatgaatta gtcgttgcta ctctagaagt
    26581 tggtcatcgg agagatattt attgaattaa agctgagtaa taacagtata gaaagtaagg
    26641 atagtaaaaa tttgaataaa aaatggttat ttgcagatta ttatgataca acaattattt
    26701 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg attgatttgg
    26761 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
    26821 gttggcgctt ttttattact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
    26881 tattgactat tctcccttta aatgctattt ttacagtgtt tcgattagga cgtatcttcc
    26941 gcttagcaag gctgacaaaa ttactgaaac tgactcgttt acttagaata attggactta
    27001 caggtaaatt agaaagaaaa attagtagat tcttacggac aaatggcctg atttatatct
    27061 tatatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
    27121 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggttatggtg
    27181 atattgttcc agtttccctt tttgggaaat ggctagcagt tttactgatg cttgtcggta
    27241 ttggaacaat agggatgcta acaagtgctt tgacgaactt ttttgtaaag gataatccag
    27301 atgaacagat aaaacttgat aaactcaaag acgaattatc gagccaaaga atattaatag
    27361 agaaacaatc tgaaaaaatc gaagaactac atcgaatgat aaaagactta gttgaaaaaa
    27421 tatcataaag gtgagacaaa acaaaacttg attcgaggag aaatcaagta agttttgaca
    27481 caatagaacg catattatca ggtataaaaa tttgataata tgcgttttat agagaaatga
    27541 aataaaattt gaacaaatca attaggaatt taaagcattt tataacaacg ttttagagta
    27601 atggggtgct atttcaactt caacctacta taatacagaa agaaacaact ccctgatgat
    27661 tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc tggatttttc
    27721 catgcttcgt caataatagc ttgcaattct ttagcagatg cttgcatttt ttgagtttct
    27781 gcatcgttca atggaatgtt tactggacga acgataccat gtgcaccaac aacagctggt
    27841 tgaccgataa agacattctc aactccgtat tgaccttctt ggaatactga aagtggaagt
    27901 actgcgtttt catcgtcaag gattgcttta gtgatacgag caagggctac tgcgataccg
    27961 tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac accttcgaac
    28021 aattcaatca attcagcttc ttgaacattt tgagtgtctt taaggaattc ttcaaggttt
    28081 acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg ttcacccatg
    28141 atgtaggcgt gcactgaacg agcatccaca tccaattttt cagcaagtgc ttgacggaaa
    28201 cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa accagagaat
    28261 ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa gatacctttg
    28321 aaaccagatt caacaacttg agttacgatt gatttgttga tagcaaggtt tttacctaca
    28381 aggtcaagac gagtttcacc tggtttttga ggtgcacctg cagtgatcac aacaaggtca
    28441 gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt gaaggcaagg
    28501 gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg aatttcgata
    28561 attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga tgaacctaca
    28621 gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat tgttttaaac
    28681 atctccttaa ttttattagg ggattttccc tagacaactt cattctatca cttttaaaaa
    28741 actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt ttagaggctg
    28801 aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat gaggcattta
    28861 ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa ggcaagtttt
    28921 atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg agatggctta
    28981 aaacctgttc accgtcgcat tctctacgga atgaatgaat tgggtgtgac cccagacaaa
    29041 ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca cccacacggg
    29101 gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta ccgttacatg
    29161 cttgtagatg gtcatgggaa ttttggttct atggatggag atagtgctgc cgctcaacgt
    29221 tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat caacaaaaat
    29281 acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt cttgccagcg
    29341 cgttttccaa accttttggt taatggagca actggtattg cggttgggat ggcaaccaat
    29401 attccacctc ataatctggg tgaaaccatt gatgtagtga agttggtcat ggataatcct
    29461 gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc aactggtgct
    29521 cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg ttcgattgtc
    29581 ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgcat cgttgtaaca
    29641 gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg cttggttcag
    29701 gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga aggtgttcga
    29761 tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa cctcttcaaa
    29821 atgacccaaa tgcaaaccaa ttttggtttc aatatgctcg ctatccaaaa tggtataccg
    29881 aaaattttgt ctcttcgtca gattttggat gcttatatcg agcaccaaaa agaagtggtt
    29941 gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat cttagaaggt
    30001 ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc tagtgaaacg
    30061 gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg tcaaagtcaa
    30121 gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa gattcaatct
    30181 gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc taagcctgaa
    30241 cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt ttctgataaa
    30301 cgccgtacag agttgatggt tggacagttc ttgagtctcg aggatgagga cttgattgaa
    30361 gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt ggatcaggac
    30421 gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt gaaagatgat
    30481 gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt cttcacaaac
    30541 aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg gactgccaaa
    30601 gggctaccag tagtcaatct cttgaaattg gatgaagacg aaagtattca gacggttatc
    30661 aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg tcacggtatt
    30721 gtgaagagaa ccagtgttaa ggagtttgcc aatattcgtc aaaatggtct caaagcgctg
    30781 aatttaaagg atgaagatga gttaatcaat gtcttgttgg cagaaggaga tatggatatt
    30841 atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt tcgtggtatg
    30901 agtcgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac agttgttggt
    30961 gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg atatggtaag
    31021 cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat gcagacagct
    31081 aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg ggatgaggat
    31141 ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa tatttcacaa
    31201 acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc tcagatagtg
    31261 actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa tgaaacagaa
    31321 ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa aatctgctga
    31381 caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt aatactcaaa
    31441 ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag gtatcaaaag
    31501 agaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct gtcaaagcta
    31561 tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca gttattgggg
    31621 gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt gataatgtta
    31681 atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa ggaaattata
    31741 gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta ttttctcctt
    31801 tagataatgc taaaaatggc atgaagattt atctaaccga taaaaataaa gtttatactt
    31861 atgaaatacg tgaagtcaaa cgtgtgacac cggatcgtgt tgatgaagtt gatgatagag
    31921 atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca gaacgtatta
    31981 ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctgat gaaatcctaa
    32041 cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa tcatggattt
    32101 cactgatttt ttaagatttt cataaaaata tagtaaaatg aaataagaat aggacgaatc
    32161 gatcaggaca gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag
    32221 tttcaatcta ctataaactt ttatgaaata tagaaaacgc ttcctaaaac ctaaagtttg
    32281 tgatataatt atcaagaaaa aagatttagg agtttattat ggtttcttca gaatttatct
    32341 caaagattga atttgcttgc aataagaaag aaagtcttta tagtcaaagc aaatttaagt
    32401 atgcgattcg ttcgatgttc gcaggtgcat ttttaacctt cagtactgct gcaggtgcag
    32461 ttggggctga cttgattaat aaaattgcac caggtagtgg acgcttcctc tttccattcg
    32521 tttttgcttg gggcttggcc tacattgttt ttttgaatgc cgagttggtc acttcaaaca
    32581 tgatgttctt gactgctggt agtttcttaa aaaaaatctc ttggagaaaa acagctgaga
    32641 ttttactata ctgtaccttg ttcaacctta tcggagcctt gatagcaggg tggggctttg
    32701 ctcattcggc agcctatgcg aatctgacac acgatagttt catctcaggt gttgttggga
    32761 tgaagttagg ccgctcaaat gaattggtct tgcttgaggc gattttggca aatattttcg
    32821 taaatattgc gattctgtca tttattttgg tcaaagatgg tggtgccaaa ctttggcttg
    32881 tgttgtcagc tatttacatg tttgtattct taacaaacga gcacattgcg gcgaactttg
    32941 cttctttcgc gattgtgaaa ttcagtgttg ctgcggattc aattgccaac ttcggtgttg
    33001 gaaatatgct tcgccactgg ggtgtgactt tcatcggaaa ctttatcgga ggaggcctct
    33061 tgatgggtct tccatatgcc ttcctcaata aaaacgaaga tacttatgta gattaagaaa
    33121 atgagcacga ttgagtcgtg cttttttcat tttcaaaata aggtaatagc tatttcttat
    33181 atcaaaatat agaaaactga tatttgtaaa ctataactca aggtgctaca atatccttaa
    33241 taaaataata tggaggtcac cttatgactc gtgattttaa atttgaaact ctacaactac
    33301 atgctggtca agttgtggct ccagctacta agtctcgtgc agtgccgatt tatcaaacaa
    33361 cattttttgt ttttgatgac acgtaggaag gtgccgatct gtttgccttg aggaaatcag
    33421 ggaacattta tactcgtatc accaatccta caacagctgc ccttgaaggt ggtgttgaag
    33481 cgctagcaac agcatcaggt atgactgcag tgacttatac gattttggcg cttgcccatg
    33541 ctggtgagca tgtagtggct gcttcgacta tttacggtgg aaccttcaat cttttgaaag
    33601 aaccccttcc tcgttatggt atcacaacaa cctttgtcga tgttgataat ttggaggaag
    33661 tagaagcagc tatcaaagac aataccaagc ttgtcttgat tgaaaccttg ggtaacccct
    33721 tgattaatat tccagacctg gaaaaactgg cagagattgc tcataaacat caaatcccac
    33781 ttgtgtcaga caatactttt gcaacacctt atttgattaa cgtcttctct catggcgttg
    33841 acattgccat tcactctgcg actaagttta tcggtgggca tggtacaact attggaggaa
    33901 taattgtcga tagtggtcgt tttgactgga cggcttcagg gaaattccct caatttgttg
    33961 acgagagtcc aagctgccac aatttgagct atactcatga tgtgggtgca gcagccttta
    34021 ttatagctgt tcgagttcaa ttgcttcgtg atacaggtgc agccttgtca ccattcaatg
    34081 ctttcctctt gctacaaaga cttgaaaccc tttcacttcg tgtggaacgc catgtacaaa
    34141 atgctgagac aattgttgat tttcttgtca accatcctaa ggtagaaaag gtaaattatc
    34201 caaaacttgc agatagtcct tattatgcct tggctgagaa atacttgcca aaaggtgtcg
    34261 gttcaatctt taccttccac gtcaaaggtg acgaggagga agcacgcaag gtcattgata
    34321 atttagaaat cttttctgac cttgcaaacg cggcagatgc taaatcgctt gttgtccatc
    34381 cagcaacaat cactcacggt caattgtcag aaaaagacct agaagcagca ggtgtcacac
    34441 caaatcaaat ccacttgtct atcggtcttg aaaatgtaga agatttgatt gaagacttac
    34501 gcttggcctt ggaaaaaatt taaagtaaaa gaagataaac agtgggtttt gactcactgt
    34561 ttttgatttt ccctcaggca tgatataatg gttacagaag tctagaaaga ggaatgtaat
    34621 gaacgaaatc aaatgtccca actgtgggga agtctttaca gtaaatgaaa gccagtatgc
    34681 tgaacttttg tcccaagtga gaacggcaga gtttgataag gaactacacg ataggatgag
    34741 gcaggaactg gccttggctg agcaaaaggc tatgaatgag caacagacta aactggctca
    34801 gaaggatcaa gaaattgcgc aattgcagag tcaaatccaa aactttgata cagaaaaaga
    34861 attggccaag aaagaagttg aacagacaag ccatcaggcc ttattggcta aggacaagga
    34921 agtacaggcc ttggaaaacc agttggcgac cttgcgtttg gagcatgaaa atcaattgca
    34981 aaagaccctt tctgacctag aaaaagaacg caatcaggtc aaaaatcagc tcctactgca
    35041 agaaaaggaa aatgagttgt ctttggcttc tgttaagcaa aactacgaag cccagctcaa
    35101 agcagccagt gaacaagtcg agttttataa gaattttaag gctcaacaat ctacaaaagc
    35161 gattggggaa agcctagaac agtatgcaga gagtgagttt aacaaggttc gtagtttcgc
    35221 ctttccaaat gcttactttg agaaggataa caaggtctct tcgcgtgggt ctaaagggga
    35281 ctttatcttc cgtgagtgtg atgaaaatgg agttgaaatc atttctatca tgtttgagat
    35341 gaaaaacgaa gcggacggaa cagagaagaa gcacaagaat gcagattttt acaaggaatt
    35401 ggacaaggac cgtcgggaga agaactgtga gtatgccgtt ttggtgacca tgcttgaggc
    35461 tgataatgac tactttaaca cagggattgt tgacgtcagt cacgagtatg aaaaaatgta
    35521 tgttgttcgt cctcaattct ttatccaatt gattggtctc ttacgtaatg cggcgctaaa
    35581 ttccctaaaa tacaagcagg agttggcctt ggttcgcgag caaaatattg acattacgca
    35641 ttttgaggaa gacttggatg cctttaagct agcttttgct aagaactata attcagcttc
    35701 gactaacttt ggaaaagcta ttgatgaaat cgacaaggcc atcaaacgca tggaagaggt
    35761 taagaaattc ctgactacat ctgaaaacca actccgtcta gctaacaaca aattggaaga
    35821 tgtctctgtt aaaaaattga cccggaaaaa tccaaccatg aaagcgaaat ttgaagcatt
    35881 gaagggggag tagaaagcaa aaatgaacgg tattatcaac ttaaaaaaag aagcaggaat
    35941 gacctcgcat gatgcggttt ttaaactgcg taagattttg ggcaccaaga aaattggtca
    36001 tggtgggacc ttggatccag atgtagtggg tgttttgccc attgcgattg gcaaggcgac
    36061 ccgcatggtt gagtttatgc aggacgaggg taaaatctat gagggggaaa tcactctggg
    36121 ctattccacg acgactgagg atgctagtgg ggaagtggtc gcagaaaccc ctgttttgtc
    36181 tcccttggat gaaaagcttg ttgatgaagc gattgcgagc ttgactgggc ctattaccca
    36241 gattccccct atgtattcgg cagttaaggt taatggtcgc aagctctatg agtatgcgcg
    36301 tgctggtcag gaagtggagc gtccagaacg tcaggtgacc atttatcaat ttgagcgaac
    36361 aagtccgatt tcttatgatg gccaacttgc ccgattcact tttcgtgtaa aatgcagtaa
    36421 agggacttac atccgtactt tgtcagttga tttgggtgaa aagcttggtt atgcggctca
    36481 tatgtctcag ttaactcgta ctagtgctgc tggcttacaa ttagaagacg cactgacctt
    36541 ggaggaaatt gctgaaaaag tagaggctgg gcaattagat tttctccatc ctttagagat
    36601 tgggacaggt gaccttgtca aagttttcct aactccagaa gaagctacag aagttcgctt
    36661 tggtcgtttt attgagctag accaaacgga caaagaactg gctgcctttg aagatgataa
    36721 attgttagcc attctagaaa aacgaggcaa tctctataag ccaaggaagg tttttagcta
    36781 gattgtttag gaataaaaat cgggtgatag ataacaattg cttgataaaa ccccatacta
    36841 atagtagaat agttttggga attataatat tccaattgtt gcgagttgta gatactcaaa
    36901 taatctatat agaaatttag aggtgtgaaa tgaagcaact taaaattctt tcagataaat
    36961 atttagagtc cattacaggt tctggtggga acttaggccc aggatttggt gtgataattc
    37021 catgatgcga aatgagtttc gagaaagggt ggagcaactt cttcaacaaa aagaaataaa
    37081 tgaaaatagt gagttgagtc acctgtttcg tcttgctata caaaatttag acagaaatga
    37141 aaaataccaa tcggtcatgg ccaatttgag tcaagggttg tcactttacc tcatgacgca
    37201 tcattaccag gcacctaagt ctgtcattga ttttggttta tggattgcca aagctcctag
    37261 ccaggaaaga gggagactgg ctttcttgca gatgcttgct caaaccctac agggctttcg
    37321 ttaaaactgt cgaacatcag agggaagact ctggtgtttt ttgctgatga gactataaat
    37381 tttgtaaaaa atgtgataga atagacgacg gataaaataa cggaggatag catgcaaaat
    37441 agaccaatca ttattggagt gacaggtggt tctggtggtg gtaaaaccag tgtttcaaga
    37501 gccattttat cgcattttcc tgatgaaaag atttccatga ttgagcatga ttcatactac
    37561 aaggatcagt ctcatttgac ctttgaagag cgtgtcaaaa ccaactatga ccatcctttt
    37621 gcctttgata cagacttgat gatcgagcag attaaggaat tgttggcagg gcgtccggtg
    37681 gacatcccga cctacgacta tacagagcat acacggagta gcaagaccta tcgtcaggag
    37741 cctcaagatg tctttatcgt tgagggcatt ttggtcttgg aggacaagcg tctgcgcgat
    37801 ttgatggata tcaagatttt tgtggatacg gatgacgatg tgcgcattat tcgtcgtatc
    37861 aagcgtgata tggaggagcg tggccgtagc cttgatagcg ttattaacca gtacttaggt
    37921 gtggtcaaac caatgtacca ccagtttatc gagtcaacta agcgttatgc tgatatcgtc
    37981 attcctgaag gggttagcaa taccgtggct atcgacctgt tgacgaccaa gattgcaaag
    38041 attttggaag aagctcgaaa cagcaaataa tcacatgtgg aggccttgcc tcctttttct
    38101 atttttccct cataatggta cataaatgga gatttttagg catatttttg gtataataat
    38161 acccatgaaa gagcaagtaa atgaatagta ggtggagatg gaaaagtatt tatcggtaac
    38221 aactttgacc aagtatctga aaatgaaatt cgataaagac ccatacttgg aacgggtcta
    38281 tttaactggt caagtttcca actttcgtaa acgacctact caccaatatt tctccctaaa
    38341 ggatgaccat gcagttattc aagcgaccat ctggtctggg atttatcaga aattagggtt
    38401 tgacctggaa gaaggaatga agatcaatgt gattgggcgt gtacaggtct atgaaccaag
    38461 tggtagctac tccatcatca ttgaaaaagc tgagcctgat ggggttgggg cgcttgcgat
    38521 tcagtttgaa caacttaaga aaaaattgac agaagaaggc ctgtttcaag aacgcttcaa
    38581 gcaagctcta ccccaatttt ctaagagaat tggggtagta accagccgta gtggagccgt
    38641 tattcgagat attatcacga ccgtcagcag gcgattccca ggtgttgaca tccttcttta
    38701 tccgaccaag gttcaaggtg aaggggctgc ggaggaaatt gcaagaaata ttgcgcgtgc
    38761 taatcaacgg gacgatttgg atttgctcat tattggtcgt ggaggtggtt ctattgagga
    38821 tctctgggcc tttaacgaag aaattgtggt acgagctatt tttgaatctc gtttgccagt
    38881 tatctctagt gtggggcatg agacggatgt gaccttggca gattttgtgg cagatcgacg
    38941 cgctgcaacg ccaacagcgg cggctgaact ggcaacacct gtgaccaagt tggatgtatt
    39001 aactcatttg caaaatcagg aaaaacggat ggcaacggca gtccgaaatg ttctatctaa
    39061 gaaacaagag gctttgaaaa aatgcagtca gtctgttatc tttagacaac ctgagcgctt
    39121 gtatgacggt tatttgcaac gcttggacca actgcaactg cgtttgaaac aaagtttgcg
    39181 aactcggatt tctgataaca aacaattagt tcaagcaaga actcatcaat tagtacaatt
    39241 atcacctgtt accaaaatcc aacgctatca agaccgttta ggacagttgg acaagctctt
    39301 aggtagccaa atggcgttag tttatgacgc caaggttgct gaggccaagc gactttcgga
    39361 agctttgctc atgttggata ctagccgaat cgtggcgcgt ggttatgcta ttgtcaaaaa
    39421 agaagagtcc gttgtagatt cggttgagag tttgaagaaa aaagaccaag taacgctttt
    39481 gatgcgagat ggtcaagtag aattagaggt taaagatgtc aaaacaaaag aaatttgagg
    39541 aaaatctagc agaactggaa accattgtcc aaagtttgga aaatggtgaa attgctctgg
    39601 aagatgcgat tactgccttt caaaagggca tggtcttgtc aaaagagctc caagctacgc
    39661 tggacaaggc tgaaaagacc ttggtcaagg tcatgcaaga agacggaaca gaaagtgatt
    39721 ttgaatgaaa aagcaagaaa aattagctct tgtcgagtcg gctttggaag atttttatgg
    39781 agaccagcag tttgcctcta gtttacggga gtctgttctc tattctattc atgctggtgg
    39841 caagcgtatt cggccttttc tcttgttaga agttctggaa gccttgcagg ttaccatcaa
    39901 acctgctcac gcgcaggtag ctactgcctt ggagatgatt catacaggga gcttgattca
    39961 cgatgacctt cctgctatgg atgatgacga ttatcgaaga gggcggttaa ccaatcacaa
    40021 gaaattcggt gaagctatgg ccattttggc tggagatgcc ttattcttag acccatatgc
    40081 cttgattgcg caggcagatt tgccaagtca gatcaaggtg gacttgattg ccaacttatc
    40141 ccttgcttca ggtagtctgg gtatggtggc agggcaagtt ttggatatgg agggcgaaca
    40201 ccagcacttg tctctggaag aacttcagac tattcatgcc aataagactg ggaagttact
    40261 agcctatcct ttccaagcgg cagctattat agctgaattg tcacctgaaa tgcaggtgaa
    40321 gctgaaaact gtgggtgaat tgattggact tgcttttcaa gtcagagatg atgtactgga
    40381 tgtgacagct agttttgagg aaatcggcaa gacacctcaa aaggatctgc aggcagaaaa
    40441 atcaacctat cctgccttgt tgggcttgga agagtccatt gccttttgta accaaaccct
    40501 ggatcaagct aatgaaaaat tagaagaaat tgcccagcag cttccctttg aaacagaatc
    40561 gattgtaagt gtagtagaaa gtttgagaat caatggctaa ggaaagagtg gatgtactag
    40621 cttataaaca ggggttgttt gaaacgagag agcaggccaa gcgaggtgtg atggctggcc
    40681 tagtcgtagc agtccttaat ggagaacggt ttgacaagcc aggagagaaa attccagatg
    40741 acaccgaatt aaaactcaag ggggagaaac tcaagtatgt cagccgtggt ggtttgaaac
    40801 tggaaaaggc cttgcaggtc tttgatttgt cggtggatgg cgcgactacg attgatatcg
    40861 gggcctctac tggaggtttt accgatgtca tgatacagaa tagtgccaag ttggtctttg
    40921 cagtcgatgt tggtaccaat cagttggctt ggaaattacg ccaagaccca cgagttgtca
    40981 gcatggagca gttcaatttt cgctatgctg aaaagactga tttcgagcag gagccgagct
    41041 ttgccagtat tgatgtgagt ttcatttccc ttagtctgat tttgccagcc ttgcaccgtg
    41101 tcttggctga tcaaggtcag gtggtagcac ttgtcaaacc tcagtttgag gcaggacgtg
    41161 agcagattgg gaaaaatgga attattcgag atgctaaggt tcatcagaat gtccttgaat
    41221 ctgtaacagc tatggcagta gaggcaggtt tttcagtcct tggcttggac ttttctccca
    41281 tccaaggtgg acatggaaat attgaatttt tagcgtattt gaaaaaagaa aagtcagcaa
    41341 gcaatcagat tcttgctgag attaaagaag cagtagagag ggcgcatagt caatttaaaa
    41401 atgaataaaa aagaaagact tgaaaaaatt agaagattgg tgacagatta tcaaatcggc
    41461 acgcaagaag aaattgtaga acatttgaaa gaagcaggta tcactgccac tcaggcgacg
    41521 gtatcccgag atatcaaaga gttaggtatt gtcaaaattc ctttgagaga caacacctat
    41581 gtctacgaat taccaaaatc aatcgtaaaa agtctgcaac tggctgaaga caatatcgaa
    41641 tcggctgaat tgatggataa gatgatcaat ctccaagtta ttccaggaaa tacggctttt
    41701 gtaaaagctc agttaatcga gacttttgca gacaagattt ttagctgttt gactgatgat
    41761 agctcgattt tagtcattgc cagaagtgga agtctagcag aggaaatctt tgaacaagta
    41821 aaaaattggt aggtctatat gttacttgaa atttcgataa aaaactttgc cattattgaa
    41881 gctatttccc tcaattttga aaaggggatg actgtcctga ctggtgaaac gggtgcaggg
    41941 aagtcgatta tcattgatgc catgaatatg atgttgggag ctcgtgcgac gacagatgtt
    42001 attcgtcatg gtgcaccaaa ggcagagatt gaggggcttt tctcagttga gaatagtcgt
    42061 cttttacagg aaatttttga tgagcaaggt ttagaattag gtgatgaaat tatcatccgt
    42121 cgggaaatct tgcaaaatgg tcgtagtatc agccgtgtaa atggtcagat ggttaatctg
    42181 tctgttttgc gagctattgg gcaacatctt gtagatattc atggtcagca tgaccatgag
    42241 gagttaatgc gtccccaact gcatatccag atgttggatg aatttggtga tgccgctttt
    42301 tgggacttga aagaaaccta tcaaacgagt tttgatgcct atcggaaaat gcgcaagcag
    42361 gttctggaag tcaagaaaaa ccaacaggaa cacaaggaac gtatcgaaat gttggaattt
    42421 caaatggcag agattgaggc agcaaacttg caggctggag aagacttggc tctcaaccaa
    42481 gagcgagata aactcctcaa ccacaaaaat attgcggata cactgaccaa tgcctacagt
    42541 atgttggaca atgaagattt ttcaagtctg gccaatgttc gttcagctat gaatgacatg
    42601 gaaagtgtcg aagagtatga tcctgaatac cgtgaaattt caagctctct gtctgagacc
    42661 tactatgttt tagaagacat tagcaaacgt ttggaagcta tcattgagga ccttgatttt
    42721 gatggcaatc gcctcatgca ggttgagaat cgtttggacc tccttcatac tattactcgt
    42781 aagtatggtg gaactgttga tgatgttttg ctttattttg ccaagattac ggaagaatac
    42841 aatctcttga caggcaataa tctttcgtct gaggacatgg aagcagagct taagaagttg
    42901 gaagtcaatc ttgtcaattt ggcaggtcaa cttgcttctg ctcgtcataa tttagctcag
    42961 caactcgaag ctgagattaa acaagaactg caagatcttt atatggaaaa agcccagttt
    43021 caggttcgtt ttagtaaggg aaaattcagt cgtgagggaa atgaaatggt tgagttttat
    43081 atttcaacca accctggaga agactttaaa cccttggtta aggttgcttc tggaggggaa
    43141 ttatctcgtc tcatgttagc cattaagtct gccttttcac gtaaagaagg caagactagc
    43201 attgtctttg atgaggtgga tacgggagtt tcaggtcgtg ttgctcaagc tattgctcag
    43261 aaaattaata aaattggtca gcatggtcag gttttggcta tctcccattt gccacaagta
    43321 attgcgattg cagattatca attctttatt gagaagatta gtaatgacca ttcaacggtt
    43381 tcgactgttc gtcttttgac ggtcgaagag cgagtggagg aagttgccaa gatgttggca
    43441 ggtgataatg tgacagaagc agccctgacg caagccagag aattgttgag aaacagggag
    43501 aaataagatg acagattatt atgtaattgg agatgttcac ggaaaagctg ggatgctgga
    43561 agaccttctc aaaacctggg atggtcagcc ccagttgctc tttctaggtg atttgattga
    43621 cagaggtgag gatagtcacc gtgttcttga aatggtcaag gacttggtgg acaatcaagg
    43681 ggctatctgt ttgtccggaa accacgagta tatgtttttg acttggctag atgacccaga
    43741 agaaagttat gaccattatc gtcgcaatgg tggagataca accattaact ctatcctagg
    43801 tcgtcccttg gatgcaccag ttgatggagt agaagatgcc aaacgggttg ccgctgaagc
    43861 ggcagacttg gtcgaattca ttcgtcaaat gccatttgta gtagagacag acaagtatat
    43921 ctttgttcac gcaggtattg atttgacctt ggatgattgg catgaaacaa cagattataa
    43981 aaaagtctgg ctcagaaaac cgttccacga agccgaaaat catactggaa aaactattgt
    44041 cttcggtcat acaccggtct atggtttgtt acagcaagaa cgcggtacat ctgagctttg
    44101 gactacagaa gatagcaaga ttggcatgga cggaggagct gtctatggtg gggtccttca
    44161 cgggattgtc tttactgacc agggaatgac agaacactac tttatcgaaa atgacggctt
    44221 tgttgctgaa gattagtact cctagcaggg tatggtcttg tcaaaatgtc aaaaacaatt
    44281 tataataaat agataccctg aaaggaagag aatcatgaac ttagaagaat tgaaaaaacg
    44341 acaggagaag atccgtaact tctctattat cgcccatatt gaccacggga aatcaactct
    44401 agcagaccgc attttggaaa aaacagagac ggtttcaagt cgtgaaatgc aggcccagct
    44461 tttggatagc atggatttag aacgggaacg tgggattacc attaagttga atgccatcga
    44521 gctgaattac acggcaaaag atggcgatac ttatatcttc cacttgattg acactccggg
    44581 gcacgttgac tttacctatg aagtttcacg ttcgctcgct gcctgtgagg gggctatttt
    44641 ggtggtcgat gctgcccaag gaattgaagc tcaaaccctt gctaacgttt atctggcctt
    44701 ggacaatgat ttggaaatca tgcctgtcat taataaaatt gacctgcctg ctgcagatcc
    44761 agagcgcgtg cgtacggaga ttgaggatgt gattggtttg gatgccagtg aagcagtttt
    44821 agcatctgcc aaggctggca tcggtatcga agagatccta gagcaaattg tagaaaaagt
    44881 accagaacca acgggtgatg tgacagcgcc tcttaaagcc ttgattttcg actctgttta
    44941 cgatgcttac cgtggggtta ttctccaagt tcgtgttatg gatggggtgg ttaaacctgg
    45001 ggataagatt cagctcatga gtaatggcaa gacctttgat gtgacagaag ttggtatttt
    45061 tactccgaaa gcagttgatc gtgatttcct tgcgacgggt gatgttggtt atattgcggc
    45121 ttctatcaag acggttcagg acacccgtgt cggtgatacc gttactttgg caaccaatcc
    45181 tgcggcagag tccttacatg gttacaagca gatgaatcct atggtctttg cgggtctcta
    45241 cccaatcgag tcaaacaagt acaatgacct gcgtgaagcg cttgaaaaat tgcaactgaa
    45301 tgatgctagt cttcagtttg aaccagaaac atctcaggcc cttggatttg gtttccgttg
    45361 tggattcctt ggacttctcc atatggatgt tatccaagaa cgtttagaac gtgagttcaa
    45421 catcgacctc atcatgacag ctccatccgt tatctataag gttaatcaaa ccgacggtga
    45481 gtcaatggat gtgtctaacc catctgagtt tccagaccca actaagattg cgaccattga
    45541 agagccttat gttaaagctc aaataatggt accgcaagag tttgttggag cagtgatgga
    45601 attggctcag cgtaagcgtg gggattttgt gactatggat tatattgatg ataaccgtgt
    45661 caatgttatc tatcaaattc cgcttgctga aattgtcttt gacttctttg ataaacttaa
    45721 gtcttcgaca cgtggttatg caagctttga ctacgaattg tcagaatatc gcccatctaa
    45781 gctggtcaaa atggacatcc ttctcaatgg agacaaggtg gatgccctca gctttatcgt
    45841 tcacaaggac tttgcctacg aacgtgggaa actcatcgtt gataagctca agaaaattat
    45901 ccctcgccaa caatttgagg ttccaattca agcagctatt ggacacaaga ttgtggctcg
    45961 tactgatatc aaggcccttc gtaagaacgt acttgctaaa tgttatggtg gtgacgtttc
    46021 tcgtaagcgt aaactgcttg aaaaacaaaa agctggtaag aaacgcatga aagctatcgg
    46081 atcagtagaa gttccacaag aagccttcct tagcgtcttg agcatggacg aagaataagt
    46141 tattataatt gttttcttgt tcacaggaaa tttacataag aatcaatagt aaaacaggct
    46201 taaattggcc tgttttttta gtttttatac tcttcgaaaa tctattcaaa ccacgtcagc
    46261 gtcgccttgc cgtagatatg atcactgact tcgtcagtct tatctacaac ctcaaaactg
    46321 tgttttgagc aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtattag
    46381 aacagaaaaa atgctggtag tatttgtttg tgtgtttatt tttatataac aaactacaaa
    46441 cgaaacaaaa atataaaaaa agagacaaaa atcaacagaa aactattgac aacggtttca
    46501 tatagtgtta tacttatggc ataaagttaa tggaaagaag ggaaaacttt atgggattag
    46561 atcatttctt tgacaaaaac cttgtgtttt gcttagaagc ggataatcaa gaacatctct
    46621 ttgatcaggt tgcaacttta ttggaagaac gagaaattgt aactccaact tatcgtgaag
    46681 ccttgatcac gcgtgaaaag tcatttccaa ctggcttaga tatggaattt ttgggtaagg
    46741 atttgccgaa tgtggctatt cctcatacag atattgttta taatctagct gaaaaagttg
    46801 tggtcgttcg attagagaaa ccggtgactt tccacaatat gattgcgcca gataaggaag
    46861 tagaagtatc cttgctcttc tttatcatca ataactcaag ttcaagtcaa accaacattc
    46921 ttgctcagtt gatggacttc tttactggaa atggtcatct tgaagaccta tcaaaaattt
    46981 ctgaaccaga acccctctat gcttatatag ctgaagcaat cgcttaatct tgtttattaa
    47041 aaatattaaa tcggaggaaa tccatatgat taaaattctt gctgcctgcg gtgcaggtgt
    47101 taactcaagt caccaaatta aaagtgctct tgaagaagaa ctttcaaacc gtggttttga
    47161 tgttcactgt gatgcggtaa tggtcaaaga cgttaatgaa gatcttatca aaggttatga
    47221 catcttcaca ccaattgctg cgacagacct tggttttgac ccaggtattc cagttatcga
    47281 agctggacta atcttattcc gtatcccagc aatgagtgct ccagtatttg acaatattga
    47341 agcagctatc aaagaacacg ggttaagcta attttaattt gttaacattc atataacata
    47401 aaaaagggag gaactgttat gtatgcaatc tttgacctaa tcggaaaggt tttcaatccc
    47461 atcttagata tgggtgggcc tgtcatcatg ttaatcattt tgacagtatt ggctttactt
    47521 tttggagtga aattctccaa agcgcttgaa ggtggtatca aacttgccat cgctcttaca
    47581 ggtatcggtg ccatcatcgg tatgcttaac actgctttct cagcgtcgct tgcaaaattc
    47641 gttgaaaaca ctggtatcca attgagtatc actgacgttg gttgggcacc acttgctaca
    47701 atcacttggg gttctgcttg gacactatac ttcttgctca tcatgttgat tgtcaacata
    47761 gtgatgctag ctatgaagaa aacagataca cttgacgttg atatcttcga tatctgacac
    47821 ttgtctatca caggtctttt gattaaatgg tatgcagata acaacggtgt gagtcaaggg
    47881 gtttcactct ttattgctac agcagctatc gtccttgttg gtgtgttgaa aattatcaac
    47941 tctgacttga tgaaacctac atttgatgac cttcttaacg ctccaagttc atcaccaatg
    48001 acatcaactc acatgaacta catgatgaac ccagttatca tggttttgga taagattttt
    48061 gaaaaattct tcccaggtct tgataaatac gactttgacg ctgcaaaatt gaacaagaaa
    48121 atcggtttct gggattctaa attctttatc ggtttcatcc ttggtatcgt tatcggtatt
    48181 atgggaactc cacatccaat tgcaggagtt gaagatgcag ataaatggcg tcttgttatc
    48241 agaggatggt tgtctcttgg tttgactgcc ggtgtatctt tggaactctt ctcacttatc
    48301 ggttcatggt tcattgcagc cgtagaacct ctttcacaag gtattacaaa cgttgctact
    48361 aaacgtcttc aaggacgtaa attcaacatc ggtcttgact ggcctttcat cgctggtcgt
    48421 gctgaaatct gggcttgtgc caacgtactt gctccaatca tgttgattga agctgttctt
    48481 ctttcaaaag tcggaaatgg tatcttgcca cttgcaggta tcatcgctat gggtgttact
    48541 ccagctctct tagttgtaac tcgtggtaaa ttgctccgta tgattatctt cggaacactc
    48601 ttgttgccac tcttccttct ttcaggtaca cttattgcac catttgcaac agaacttgct
    48661 aaaggtgtag gtgccttccc agcaggtgtg agccaaactc aattgatcac tcactcaact
    48721 cttgaaggac caatcgaaaa acttcttggt tggacaattg gtaacactac aactggtgat
    48781 atcaaagcaa tccttggtgc tgtagtcttc cttgtattct atatcggtat ctttgcttgg
    48841 tacagaaaac aaatgatcaa acgtaacgaa gagtacgcag caaaagcaaa ataatgcgct
    48901 cctataaaat gtaa
//
LOCUS       DAVDZK010000013        48368 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVDZK010000013 DAVDZK010000000
VERSION     DAVDZK010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48368
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.013"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(431..886)
                     /locus_tag="VUX16_000847"
     CDS             complement(431..886)
                     /locus_tag="VUX16_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123840.1"
                     /translation="MGAARDFLELINYKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(1212..2900)
                     /locus_tag="VUX16_000848"
     CDS             complement(1212..2900)
                     /locus_tag="VUX16_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HET8123841.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQLFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DHHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPALYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNC"
     gene            complement(3063..3896)
                     /locus_tag="VUX16_000849"
     CDS             complement(3063..3896)
                     /locus_tag="VUX16_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET8123842.1"
                     /translation="MDYKEKLENKAKEYFEYVETKITEKALDATHFAEEASREQYDAV
                     VVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLEINQDIDGAIDELDFDLT
                     NKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILTYAVNTMKSVMTDQVFNI
                     KVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANILILKDASIFSKLSVIPDL
                     LKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPVEIKVLAQRVEVFSKPKE
                     D"
     gene            complement(4058..4912)
                     /locus_tag="VUX16_000850"
     CDS             complement(4058..4912)
                     /locus_tag="VUX16_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET8123843.1"
                     /translation="MLGAITGDIVVSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(4970..5728)
                     /locus_tag="VUX16_000851"
     CDS             complement(4970..5728)
                     /locus_tag="VUX16_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET8123844.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMEIRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYELDIGVTRDGRTLVVEVNDGYALGNCGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(6029..6595)
                     /locus_tag="VUX16_000852"
     CDS             complement(6029..6595)
                     /locus_tag="VUX16_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123845.1"
                     /translation="MVILELYQNDYSKDLVAFNSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESCGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(6863..8221)
                     /gene="rlmD"
                     /locus_tag="VUX16_000853"
     CDS             complement(6863..8221)
                     /gene="rlmD"
                     /locus_tag="VUX16_000853"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET8123846.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTDSFI
                     KASAQTGVDRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVECVSLLEK
                     RN"
     gene            complement(8295..9269)
                     /locus_tag="VUX16_000854"
     CDS             complement(8295..9269)
                     /locus_tag="VUX16_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET8123847.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVTFFKSFGS"
     gene            complement(9343..9957)
                     /gene="pmp23"
                     /locus_tag="VUX16_000855"
     CDS             complement(9343..9957)
                     /gene="pmp23"
                     /locus_tag="VUX16_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET8123848.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSISG"
     gene            complement(9957..10931)
                     /locus_tag="VUX16_000856"
     CDS             complement(9957..10931)
                     /locus_tag="VUX16_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET8123849.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSENLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(10939..12195)
                     /locus_tag="VUX16_000857"
     CDS             complement(10939..12195)
                     /locus_tag="VUX16_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET8123850.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVESLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMALIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFRETADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHIVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQAPDFRIISGGTENHLFLVDVTKIVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     AENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(12256..12687)
                     /locus_tag="VUX16_000858"
     CDS             complement(12256..12687)
                     /locus_tag="VUX16_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8123851.1"
                     /translation="MLRDLRETDVKAICEINQEALGYSFSPEDTASQLAKLSQDSHHF
                     LLGYEDAASHVLLGYVHAEVYESLYSKAGFNILALAISPQAQGQGIGKSLLQGLEQEA
                     KRRGYGFICLNSADHRLGAHAFYEKVGYTCDKVQKRFIRIF"
     gene            complement(12689..13291)
                     /locus_tag="VUX16_000859"
     CDS             complement(12689..13291)
                     /locus_tag="VUX16_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET8123852.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDCVYQLKRR
                     PRDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TVGFRMPSHPITLDLIRETGPLIGPSANISGQTSGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTILDLSGDKVKILRQGAIKREDILAQLPEISFEEE"
     gene            complement(13275..14114)
                     /gene="prmC"
                     /locus_tag="VUX16_000860"
     CDS             complement(13275..14114)
                     /gene="prmC"
                     /locus_tag="VUX16_000860"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET8123853.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLATHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLEENLQVLDIGTGSGAIALALAKNRPAWSVTAADISQDALELASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREGESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPALFKKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(14114..15193)
                     /gene="prfA"
                     /locus_tag="VUX16_000861"
     CDS             complement(14114..15193)
                     /gene="prfA"
                     /locus_tag="VUX16_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET8123854.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(15190..15780)
                     /locus_tag="VUX16_000862"
     CDS             complement(15190..15780)
                     /locus_tag="VUX16_000862"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET8123855.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            15903..16085
                     /locus_tag="VUX16_000863"
     CDS             15903..16085
                     /locus_tag="VUX16_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET8123856.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            16222..17595
                     /gene="mnmE"
                     /locus_tag="VUX16_000864"
     CDS             16222..17595
                     /gene="mnmE"
                     /locus_tag="VUX16_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET8123857.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(17642..18577)
                     /gene="dapA"
                     /locus_tag="VUX16_000865"
     CDS             complement(17642..18577)
                     /gene="dapA"
                     /locus_tag="VUX16_000865"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET8123858.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(18633..19709)
                     /locus_tag="VUX16_000866"
     CDS             complement(18633..19709)
                     /locus_tag="VUX16_000866"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET8123859.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(20294..20366)
                     /locus_tag="VUX16_000867"
     tRNA            complement(20294..20366)
                     /locus_tag="VUX16_000867"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20331..20333),aa:Thr,seq:ggt)
     gene            complement(20466..20975)
                     /locus_tag="VUX16_000868"
     CDS             complement(20466..20975)
                     /locus_tag="VUX16_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET8123860.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(20973..21069)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            21098..21529
                     /locus_tag="VUX16_000869"
     CDS             21098..21529
                     /locus_tag="VUX16_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET8123861.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQILIIIINYILSKIYIFRK"
     gene            21611..21988
                     /gene="mscL"
                     /locus_tag="VUX16_000870"
     CDS             21611..21988
                     /gene="mscL"
                     /locus_tag="VUX16_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET8123862.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(22030..23124)
                     /gene="hemH"
                     /locus_tag="VUX16_000871"
     CDS             complement(22030..23124)
                     /gene="hemH"
                     /locus_tag="VUX16_000871"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET8123863.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEDRLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILEEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTIRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            23279..24502
                     /gene="pepT"
                     /locus_tag="VUX16_000872"
     CDS             23279..24502
                     /gene="pepT"
                     /locus_tag="VUX16_000872"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET8123864.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNLLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(24538..25167)
                     /locus_tag="VUX16_000873"
     CDS             complement(24538..25167)
                     /locus_tag="VUX16_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123865.1"
                     /translation="MSKANQLLEQIHEEGIRKSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETGSDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            25132..25353
                     /locus_tag="VUX16_000874"
     CDS             25132..25353
                     /locus_tag="VUX16_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123866.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(25430..26077)
                     /locus_tag="VUX16_000875"
                     /pseudo
     CDS             complement(25430..26077)
                     /locus_tag="VUX16_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521835.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(26181..26741)
                     /locus_tag="VUX16_000876"
                     /pseudo
     CDS             complement(26181..26741)
                     /locus_tag="VUX16_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(26967..29144)
                     /locus_tag="VUX16_000877"
     CDS             complement(26967..29144)
                     /locus_tag="VUX16_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET8123867.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQAKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKKEGINAEQIVIKITAQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SSNHGVDSNDKAVVAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSN
                     QIGQPTLPNNGLTTPSPSLPVNPDVSHEEHEEDGHGFDANRIIAEDESGFIMSHGNHN
                     HYFFKKDLTADQIKAAQKHLEEVKTSHNGLDSLQSHEQDYSGNAKEMKDLDKKIEEKI
                     AGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVGIGHSHSNYELFKPEE
                     GVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVSFSFPPELEKKLGINM
                     LVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFKYTIASKDYPEVSYDG
                     TFTVSTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDALVRVFDEFHGNAYLEN
                     NYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYIVEVPILEKENQTDKP
                     SILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLTETRNSTSNSTLEEAPAVDPVQE
                     KVEKFTASYGLGLDSVIFNMDGTIELRLPSGEVIKKNLSDLIA"
     gene            complement(29342..31822)
                     /locus_tag="VUX16_000878"
     CDS             complement(29342..31822)
                     /locus_tag="VUX16_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET8123868.1"
                     /translation="MKFNKKYLAGSVAVLALSVCSYELGRHQAGQAKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKKEGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQIAYRTANGVAVPHGDHYHFIPYSQMSPLEEKLA
                     RMIAIKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENHLSKKTQETHALVAKKESVASRDREFYDKAYNLLTQAHK
                     ALSENKGRTSDFHALDKLAERLNNESSNKVKLVDDLLTFLAPITHPERLGKPNAQIAY
                     TDDEIKLAKLAGKYTTEDGYIFDEHDIESDEGNAYVTPHLNHSHWIKKDSLSEAERAA
                     AQAYAKEKGLQAPNSTEATEAKTEATGTEAIYNRVKAEKKVPLEKIPNHLQYTVAVQN
                     GHFIIPHFDHYHNLKFAWFDEGLYSAPEGYTLEDLFATVKYYVEHPDQRPHSDNGWGN
                     ASDHVRKHQADQDSKPDENKEHEEVSEPTRPESDEEENHAGLNPSADNLYKPSTDTEE
                     TEEEAEDTTEEAEVPQVERSIIEVKITEAEALLAKVTDSRIQQNAMETLAGLQSSLLL
                     GTKDNNTILAEVDSLFALLKESKPTPIQ"
     gene            complement(31830..32747)
                     /gene="adcAII"
                     /locus_tag="VUX16_000879"
     CDS             complement(31830..32747)
                     /gene="adcAII"
                     /locus_tag="VUX16_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET8123869.1"
                     /translation="MKKQNLFLVLLSIFLVCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLDRVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQSKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            complement(32890..34281)
                     /locus_tag="VUX16_000880"
     CDS             complement(32890..34281)
                     /locus_tag="VUX16_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET8123870.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLA
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWHIKLDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSQLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLMPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNTCTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMETWIAFLVALLIGSLI
                     YFTYGYKHSTIEE"
     gene            complement(34403..34969)
                     /gene="sdbB"
                     /locus_tag="VUX16_000881"
     CDS             complement(34403..34969)
                     /gene="sdbB"
                     /locus_tag="VUX16_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET8123871.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEEAKKTQAPEQSPKQQQQTPVQ
                     QIAVGKEAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPD
                     RDFEILTVIAPGIQGEKTVEQFPQWFQDQGYKDIPVLYDTKATTFQAYQIRSIPTEYL
                     IDSQEKIGKIQFGVISNADAEAAFKEMN"
     gene            complement(34980..35687)
                     /gene="ccdA2"
                     /locus_tag="VUX16_000882"
     CDS             complement(34980..35687)
                     /gene="ccdA2"
                     /locus_tag="VUX16_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET8123872.1"
                     /translation="METIVFSISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWLGLIRTLCFIAGISLIFFILGFGAGYFGHVLYANWFRYVMGVIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSVFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMAIPFLVLALASGIVMPYFSKLKRHMMLLKKIGGFLIILM
                     GILLLLGQVNVLAGIFE"
     gene            complement(35918..36334)
                     /locus_tag="VUX16_000883"
     CDS             complement(35918..36334)
                     /locus_tag="VUX16_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123873.1"
                     /translation="MKAALNSLKDVPANASDSKPAQDKKDAKQGTEDSKDSAKMTETT
                     SVPPGVIVVSLLVLLGVIAFWLVRRKKESEIQQLSTELTKILGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETEAKLVEELKSILAKLK"
     gene            complement(36621..37118)
                     /locus_tag="VUX16_000884"
     CDS             complement(36621..37118)
                     /locus_tag="VUX16_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET8123874.1"
                     /translation="MKKIEVKGLAKTVKDKAIQNIENAQDETTLNTAKNNGITNIGKV
                     TLPRTTKKAEAKEAINAAAEAKKTEISNRFDLTIEDKSRALQQVDQEANDAKIAVDKG
                     VTNKDVEQAKVVGIDAINNINPQPTSRPLSTPQPQPSTPTQPDQGDTETPTTPSSPSA
                     QPSQL"
     gene            complement(37072..37245)
                     /locus_tag="VUX16_000885"
     CDS             complement(37072..37245)
                     /locus_tag="VUX16_000885"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123875.1"
                     /translation="MSDAVTIPTPTTPTLDKDGAKNEVEQAFSTKTSNIDKDNSLTNE
                     KNRSERISENSKR"
     gene            complement(37524..38247)
                     /locus_tag="VUX16_000886"
                     /pseudo
     CDS             complement(37524..38247)
                     /locus_tag="VUX16_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(38609..40372)
                     /locus_tag="VUX16_000887"
     CDS             complement(38609..40372)
                     /locus_tag="VUX16_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET8123876.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDTYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     SQEDPEYTDLLLKKALEFFEF"
     gene            complement(40381..40971)
                     /locus_tag="VUX16_000888"
     CDS             complement(40381..40971)
                     /locus_tag="VUX16_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET8123877.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTNVPLKSFINGLTGITAETLKDAPPVEKVIKEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            complement(41069..41560)
                     /gene="rocS"
                     /locus_tag="VUX16_000889"
     CDS             complement(41069..41560)
                     /gene="rocS"
                     /locus_tag="VUX16_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET8123878.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            complement(41637..42329)
                     /locus_tag="VUX16_000890"
     CDS             complement(41637..42329)
                     /locus_tag="VUX16_000890"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET8123879.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIVTGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKTLD"
     gene            complement(42346..42660)
                     /locus_tag="VUX16_000891"
     CDS             complement(42346..42660)
                     /locus_tag="VUX16_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET8123880.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            complement(42672..43217)
                     /locus_tag="VUX16_000892"
     CDS             complement(42672..43217)
                     /locus_tag="VUX16_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET8123881.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            complement(43227..44606)
                     /gene="glmU"
                     /locus_tag="VUX16_000893"
     CDS             complement(43227..44606)
                     /gene="glmU"
                     /locus_tag="VUX16_000893"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET8123882.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVASISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            44750..45550
                     /locus_tag="VUX16_000894"
     CDS             44750..45550
                     /locus_tag="VUX16_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET8123883.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFFES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            45645..46487
                     /locus_tag="VUX16_000895"
     CDS             45645..46487
                     /locus_tag="VUX16_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET8123884.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            46487..46969
                     /locus_tag="VUX16_000896"
     CDS             46487..46969
                     /locus_tag="VUX16_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET8123885.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGNKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYHIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            46969..47589
                     /locus_tag="VUX16_000897"
     CDS             46969..47589
                     /locus_tag="VUX16_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET8123886.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(47842..47937)
                     /locus_tag="VUX16_000898"
                     /pseudo
     CDS             complement(47842..47937)
                     /locus_tag="VUX16_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            48216..48350
                     /locus_tag="VUX16_000899"
     CDS             48216..48350
                     /locus_tag="VUX16_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET8123887.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFEINNSNIRYMIKLIDR
                     "
BASE COUNT        14170 a        10130 c         8547 g        15521 t
ORIGIN      
        1 tttttataaa tccattatag cataaaaaag cataacgcac caaaaatggt gcgttatttc
       61 ttgtttgtct atcctaaact ttacttctat aaaagtcacc taaagagcca taaatattta
      121 ttcttgtatt aattttttcg atgcgcaaac gatatctaca aatacatcta taacgattca
      181 ccttttagga tttttattgt caaaattgtc tttatctaca aagacaaaat gcttataaaa
      241 tagcttgaaa tcaaggatta tcaccttttt cgttgtagca acactccaca tgtgattatt
      301 aggctattag caaagcgtat ccaatacctc aataaagtgt tgtttttact gatattttaa
      361 ctatattgta tagtctacta tttaaatctc aattaggata ttttatagaa tacccaaaat
      421 tcaacaataa ctaaaagtaa gattccattg tatttccttg ttggtctttc atatcacgaa
      481 ttttattttt cagaatatta aagttacaaa tttcatctct aatatcgtta tccgctctgt
      541 agccattaat catctcagtc agagttttcc ctttactacc attctttata gtagtattta
      601 ctctttttat actgctttca aaaggctcat atgttttata cttaattact tcgtctttaa
      661 aattaaataa aggtgtatcc ggcttagcat tccataaaat aatcaaccac attatagcat
      721 tataaagctg ctttgcagtt tcattccact tttcaggttg taaatttcca ctccctgtat
      781 tgtcatattc ttgtctatta tttacatgag aatcacctac aagcggatta aaaagaggta
      841 gccctttgta attaattagt tctaaaaaat cccttgccgc acccatgcaa cactgaataa
      901 cttccttctt gccatcaatt ttactctcag cgataaatac ataatattca tcttcaatag
      961 ttgctcctgc atcactatgt ttttgttgat ttgctaacag cttaatatgt gctttaggct
     1021 aaacttcaaa atctctaaca attctttgtc ttgtttcatg tcctctacaa ttcatttaag
     1081 ttctccttta caagtttagt aactagcctt attatactat ataagatatg aaatgtacca
     1141 taatcttcat caactagttt ttagaaaatc acaaatccat ctggagagat gacaagctga
     1201 ttctccaatt cttagcaatt gcttgctagt gctactgctt ctttctctaa aagataatct
     1261 tctgttgatt ggttgaatat tgctttgagg atccgtcctt cgtatttcca ttccagagct
     1321 actagatcag atttgatttc ttgaaggcta tacttgccat gcgaaatgat tactgacgcg
     1381 tatttccgaa tcttaattag cctcttcata aagttcagca tatcattgtc acttgataca
     1441 cgttcccaag gcatacaacg acggcaatct ggatctggtc ctccagtcaa ggctagctcg
     1501 gttccgtaat aaatgcacgg tgttcctttt tgtaaaaaga gaaaggctaa ggctgattta
     1561 accagttgaa catcttcatt ggccgtccac aggattcgct ctgtatcatg tgaatccaag
     1621 agattaaaca tgacctctga aatctgctgc ttgtaataca tagactctcc attgatttca
     1681 tcgatgaact ggtctgtctt cttaattcct cgtaagaaat agtccttgat actatcagat
     1741 aaaggataat tcatgacggc atggaactca tctccattta gccaaggctg agatgtatgc
     1801 cagacttctc ctaggatata aagagcagga tttttagcta aaactgcctt acgaaaatcc
     1861 ttccagaact gatggtcaat ctcattagcc acatccaaac gccaagcatc gatattaaac
     1921 tcttcaatcc aataagtcgc aacctttaaa agataattct tgacctctgg attggctgta
     1981 tttagcttag gcatatagtc ctcgaaacca aaaacatgat agggtaagtc tctcttatta
     2041 actagctttt cagttgtcac tgggaattgt tgaatatgga accaatcctt ataagcagac
     2101 tgttcaccat ttttgacgac atttttccat tgaagagatt gcgaaccaat atgattaaat
     2161 accgcatcca gcatgacttt catgccacga tgatgcgctt gatccaccag ttcccgaaag
     2221 gtctccttgt ctccaaaatg atggtcaatt tcaaagtaat ctgtcgtatt gtacttgtga
     2281 ttgcttgtag attcaaagat gggacaaaga tatagtccag taatacccaa gtcttgcaag
     2341 taatccatat gatcaataat cccctgtaaa tcaccaccaa agaaatcatc gctcttaggt
     2401 gtgacagatg aatcccagtc taaagtccct tctgggttta atagagcatt gccattggca
     2461 aatctttcag gaaatagctg ataccatacc gtatttgaaa cccagtcagg aaccttgcag
     2521 gcatcaatct catgaagata aggcaactta aatccattcc caattgcatg aagattttct
     2581 agagaatttt ccacacaccc tttatcgcca tacaaaatat tttgaccttc tgtatctctg
     2641 agctcaaaga gatactggat acgtgcaaag tcaactgaca cttcaacctg ccaatggtca
     2701 aataaggtac cagaagttat cttgaccatt tcttttgtat cctgataaaa ctcctccata
     2761 aagataaaag ggtccccata gtgcaagttg atgctttcaa tgtccccttt cttagttcga
     2821 attcgaatat ggagtttctt atccttataa agataggcat actccgactc aggcctatgg
     2881 taaatagcac tcaattccat caatttgtct cctaaagtat tcattcaaat tttacgcaaa
     2941 cgttttcaaa cttaatgaat ccagtatact atttttgtaa actatttgca aggaatgtcc
     3001 gttgttaaag gaactatctt ttaaagtata caaaaagcct taaaaaaggc tttctctata
     3061 tactaatcct ctttcggttt tgaaaatact tctactcgct gagctaggac tttgatttct
     3121 acaggtaggt tatctgattt atctccgtca acatctgact ccaattcact atctgaagag
     3181 attttaatat tacgcgcttt gatatactcg atattatcat ttgcgacaac atcccctttt
     3241 aataaatcag gaatgacgga taatttggag aatatagagg catctttcag aatcaaaatg
     3301 ttggcatagc cgtccttgtt ttcttcaaag attttcttat cagcgaagta atttgtcaaa
     3361 aggaccaaaa catggctagc ttcaccaaca taatttccat tttctgtctc aaccttaatg
     3421 ttaaagacct gatctgtcat gacagacttc atggtattta cagcataggt taaaataccg
     3481 aattttgttt tgtcctctat ttcaacattg tgaatcgcct caggcagaga accgatacta
     3541 aagatataac caaaatagtt gtcatttgct ttaccgatat caatcttatt ggttaaatca
     3601 aaatccagtt cgtcaattgc gccatcgatg tcttgattga tttccaaaag ttttgtaatg
     3661 aggttacccg taccgcctgg gataatccct aacttaggaa tgtagtctct ctcatcaata
     3721 cctgaaatga cttcattgac agttccatct ccaccaaaca caaccactgc atcatactgc
     3781 tcacgagaag cttcttcagc aaaatgtgtt gcatccagcg ctttttcggt aattttggtt
     3841 tcaacatatt caaagtattc ttttgcttta ttctccagct tttctttgta atccaaagcc
     3901 ttctcgccac agaagtaggg ttgataatta ccattgcttt tttcattgat tttatcctta
     3961 attttaaaca gaaatgttta catttcgtcg tatgcaagta aatgtaatcc tattatacaa
     4021 tgaaaataca gaaaagagaa atctgacgta ctggagatta atacgctttt attctatttt
     4081 cccatcgcct aactacatcc tttaagggtt catccaagta agaataggcc ttatccttga
     4141 tccaatcagg aataccgtaa gctgcctctg ctatgctaca agtgattgct gcgagagtat
     4201 cactgtcgcc accaagtgag atggcatttc ttatcgcatc ttcgaagtct ctactttcaa
     4261 gaaaggcgat aatggcttga gggacagttt cctgacatgt ttcgttaaaa cgatagttag
     4321 gacggatttc atctaaagtt tgagatagat tgtaatcgta ttctttttct atataatcct
     4381 taattcgtct tttacactct gtaggattgt cgttaattga ttgctcgtac tctctacaat
     4441 aaccaccaaa gtaaaaacga catagaaaga tagcatcagc tgtagccata gcgcctttga
     4501 caccttctgg atgattatga gttacctctg cagaaagact cgtaagtcct ctagatgatg
     4561 gccatatacc agttttcgca taaaaaccac agtccatgat ccaagcacat ggagaaatac
     4621 gcatagctga tccattccca aagctattat aaggctcacg gttatcgctg tttagccatg
     4681 cattaaaccg agcaccgtaa tcagcattcg gatacattct gccatatttc ttcatcgcgt
     4741 caatgaagtc gtctttttgt ccaccattca taattgcttc tgcaacagca caggtcataa
     4801 ccgtgtcatc tgtaaaaaag cagtccttcc gaaataaagg aaagtccttt gttttgatat
     4861 tgttccattc gtaaacagaa acgacaatat ctccagtaat tgctccaagc atcagattcc
     4921 tccttgttca ttttgatgct ttttatattg gttatctacc atatttattt tagaaaataa
     4981 catcctgttg gattttaaaa atttcatttt tttcaaaata gggttttacc atttctttcc
     5041 acctagctct atgaaaattg attgatttta aaggagatag gccacaattt cccaatgcat
     5101 aaccatcatt tacttcaaca acaagtgttc tgccatcgcg agtaacaccg atatctagtt
     5161 cataagctat tggcgcatct ttccaacatg atatcgcttc atcaattaca cttgcatcaa
     5221 attgtgcatg ataatcacct gtatagggtc gaacatctaa tacgcgacca tctaacacaa
     5281 aacaacgcca ttcagctatg aattctacaa cctcactaat ccatatagga tagtcgaaag
     5341 gtagaccaat acctattaaa tcatgggttc cattaacaac tcttccagta aagacttttg
     5401 aaccagcttt aggcttaata aattttcccc aattatcagg tatattcaca atctctccta
     5461 aaataccagc ataaatcttt cgaccataaa actctttaag ctcaatagga taatcataaa
     5521 ccggaacgtt taagcccatc atttttagta atgctctaat ctccattata taatctacaa
     5581 ctatatcttc acttgttaac tcttttattt cagaaaaaga ttgatataaa ataacttctt
     5641 ctccttgtaa gtaggcacct acttgagcat tgtatttatt aattgaaacc tcacttggta
     5701 atttactttg tctaatataa acaaccattt catcactcct atatcactag tgtcaactgg
     5761 cttttataat acattagttt aaaagtggag aggattttta acacagtaac tttaaatctt
     5821 tggtattaaa aaattttcac aatatttata gaaataaaat ctgtctcaaa tcagttatca
     5881 aatctagtat aaattatgag cggccactct aatactttcc ctctaaacaa gaaaaagact
     5941 tacactcaag ggttttctta cccccttcgt tataacgttt tgactctttt actagcaaag
     6001 gtatatattc acaaggaact ttggttgact attgaatctc tccaacttct tctttaacat
     6061 atccttctac atcttcaatc tctacaaaca ttgggtctaa gtgacacaag aaatgccaaa
     6121 cttcgatccc tttttttctg taaagaatcg cttcaccgtc ttcacttccg aaaaagcttc
     6181 tgtcgatttc atatccgcag ctttctaaga agtcttttgc tttacgatag ttcgtttctc
     6241 ttgtttcgac ataggcttta acttcatggt tgttaacgac atatgcatca atttttgaat
     6301 atccttcgat cactctatca tttttgaggg ataaatttga aatctctttc caaataatgt
     6361 ttacattttc ctcaggatcg aacataaatt tagataaagg aacaatattt ccgttaaaaa
     6421 taatttccat ataatccggt atgtttttag gattaaaata ctccacttca aaaccatctt
     6481 ctgtttccag agtgtatccc gggatttgag ctacaaaggc tttcccatct tctatggaat
     6541 taaatgctac taaatcttta gaataatcat tttggtacaa ttccaatata accatcgata
     6601 atctctccat tttcattatc aggctaatgt aaataagcac gtcacctgac caattcaggc
     6661 tctctgtatc atctcatcat atttcctact tactttacga gtcctatacc cagaacacac
     6721 cttatcgacc ttcggtctca cctcgtcgca ttggctgaac atctactttt acttcgctga
     6781 tgcttcaact cgtacaagca gtgataccgc ctcagcgtga tgcctcagtg ggactcaaaa
     6841 ggttcaggga accttttgag gattaattgc gtttctctaa caaactcaca cattcgacgt
     6901 gatgcgtttg aggaaataga tccaccggct ggactttctt caattcatat cccaattctt
     6961 ggtagagttt aatatcacgc gccatggttg cgacattgca ggaaatatag gcgatgcggt
     7021 ctactcctgt ttgagcgctt gctttgataa agctatcggt caatcccttt cgtggtgggt
     7081 cgaccaagat aacggttggt tgaatacctt ccttgagcca tttcttcatg gcattttcag
     7141 ccgtgtcaca gacatagtgg gcgtttgaaa tattgttcag ctgagcattt tttttactat
     7201 tctcaaccgc ttctggaatc agttcaacac cgtagacttc tttaacatgc ttggcgactg
     7261 ataaaccaat ggttccaata ccagaataag catcaataac cacgtcatct ttttttaact
     7321 ctgcaaagtc aatggctgtt tgatagagtt tctccgccat ttcagtattg acttggtaaa
     7381 aggctgggcc agcgatttgg aagtcatttc ccaacatctg gtccgtaata tagtcttgac
     7441 cataaagagt gcgccactcc ttaccaaaaa tcgcattggt attctggtcg ttgatatttt
     7501 gcatgacaga cacaatctct gggaactgct tgataacttg ttcaatcaat tggtcaacac
     7561 gaaaaacttt tggacgagtt gtcaccaaaa cgaccatgat ttgtcctgaa tagtgaccac
     7621 gacgcaccac aagattccga atcaatccag actgttcctt ttcgtcataa ggttttaaat
     7681 caaaacgacg gagcaggtct cgaagagcta ctacgacttg gtcaatgaca ggatcctgga
     7741 taaagaaatc ttcaaggggc atgaggttgt gcgaattctt acggaaaaat cctgtttcca
     7801 agacaccatt cactcgacga acgggcacct gcgccttatt gcgatacttg actggatgtt
     7861 ccataccaag cgtttcagca acttctacat ctgcaattcc agcaatcttg tagagactgt
     7921 ccttgacttg cttggtttta aacttgagct gttctggata agaaaggtgt cctaaatccg
     7981 cgattcctga acgcaggtaa gccaaatcta gatcttgatt acggtgtggt gactggacaa
     8041 ggtatttttc aacttttcca aagccaatct ttttattgac cttgaggaca cgcatgagaa
     8101 ttttttcact cggtaaagca ttctctacaa aaaagaccaa accatctacc ttggcaactc
     8161 ctgccccttc atgggtcaag tcaacaattt caacttctac aatatcattt ttctttaaca
     8221 ttcttttctc tttctattgg ccgacaaaaa agacggcaac gttacggtta ccatccatta
     8281 taccatgaaa tttcttaaga accaaaactc ttgaagaagg tgacaagggc ttgccagagg
     8341 gagcttaaga agttaccacc gtcctctagc gccttatccg catcaaagtt aaggttgata
     8401 tttttaaaac tgtcgccagc ttgtgatacg atgctttgtt taaggtcatt tagggtttta
     8461 gtgaaatctg cattgctgag gatatcactc tttgagagat tcaaggcaaa attgatgatg
     8521 atattgatct ggtttcctgt tatgacctga tcaagtttgt aattttttaa ggtatcttca
     8581 acaatcttgc ggatatcttc ttctgtcaga tttcccttgc tttctttagc tttggcgagt
     8641 cctgacttga tatcagctag ggcaacgttt aatttattag catcatagcc tgatttgtcc
     8701 ttgttttcag cattgatatc tgacaaagcc ttcaactctt cttgagccaa atctttatta
     8761 gcttgtggca ccttggctcc attagcctct agcgaatagt aaatccctgc taaagcactt
     8821 tctcctgtaa ctggaatagg ggctgctaca gtgattttgg catgttccat acccagcgtt
     8881 actgctgcgt ttcggtacat atcctgagtc accttagtga tattttctgg tgtttcaatc
     8941 ttgacctcaa gtggcgattt gtcacctagc ttttgaatct tggctgatga atacaactgt
     9001 aagctagagt cattggccac attcatgatt ttagaataaa catcaggtgt catggtcttg
     9061 agttctttgg tatctgttga ggcattgtac cccagttttt taagagtttg atttttttgg
     9121 tcttcagata gggaagaacc taggacatat tcaggttgga cataggtttc atcgataact
     9181 ttttgaacat ctgttgctgc atggacgcta ttcatagctg ttactgccca caagatcgca
     9241 gcgctagtca gaaagagttt ctttctcata gggaatttcc tcctttactt ctttagagta
     9301 atatatctat cttaaagaaa acttataaca aaaacacctg gtctagccag atattgaaaa
     9361 gagagtgaaa catttgatga tgtaaaggtt aagtcgtacc tgtctagaat aataatagtt
     9421 tcctccattt acatagagtt cagcaccgtg aaaaatggaa atggggtgaa tataactata
     9481 agtctttcca gtcgtattac caagcaaggg ggcaacagtc tcacgagagt actgtttggc
     9541 tagagccaag gtattttcct tgccattttg ggcgataaaa tcgatatagg caggtccaaa
     9601 attataggct tgaacagctg tccagatatc tacacccttc ttctgcgcca gatagagatt
     9661 gcctgtcaga gtttgaatgc cttgccgaat gctagaggca ttatcattga tggtgttggt
     9721 tgaaccactt gcagactcac tagactgcat aacatcgcct tcttttcctt ttgtttcagt
     9781 ataaatcata gcaagcacaa gctcttcgtt tgctggagtg tctttttcac tcaagatttc
     9841 tcgcaccatg ggttgatagg tcatgacttg tttgacatct tgatgaacgc ggtaagcttt
     9901 atagccagca aaaaggaaga ctgctagtac aagcactctt cgaattcgtt taaacattat
     9961 ttactttgga tatcctcgat atttttgatt aagatagagt aggttccatt ttcgttttgg
    10021 ataaactcaa cagactcggc gtcttgatag acgttattgg gaacgatgag ttcaattcca
    10081 tttgataagg agagtttttg gttttcaaat ttctttaatt ggcgactggc atcaatttca
    10141 tcaaattgaa caggttctgg tacggcttct ttgacttggt caataaagct caaacgagcc
    10201 gtcagattgt tgtcaaaaag gtcattagcc aatttctcag gtgacaattc attgctttct
    10261 tctagattgt tgaaaatagc tgatttgacc ttggattgaa attgaaaatc atctgtgtta
    10321 aaagattcgg caattctctg ggctgttttt tccagttcct tgatggattt cttaggtgaa
    10381 atcttggggg caacagctag gagattttct gaaaaatagt tcaaaaaagt cccgttgtac
    10441 ttgattcgtt tttcaatcag atggtacttg cgactctgaa gattgactac caaggcctcg
    10501 tcagcacccg ttccaaatcc aggcaggtta ttctgagtca gcttgattgg attatcaact
    10561 tctcctccga ggtgggtcaa ggtctcccgc agggcaattc gcaagaaagc gaaatgttct
    10621 acaccttctt tagaaaattg aacaaaaatc aagtcattgg tcttgagatt ttcagaaatg
    10681 ctaaactcct ctttccagag attagccagc gttactgatg tctccaacaa atcgtctgta
    10741 atatgattga agaagggatt ttcttcttcg aaaatcccag tcttggcttc atctgaatac
    10801 acatgttcaa tttttttacg caggtattct tcgatttttg gagtaatatt gagaaactta
    10861 tctgctaaga acagctcggt atcatccgga ctgaactggt gaataatggc tttcttaata
    10921 taaatgtcca taaaagtttt agtcctcgta taatgggaag gcatctgtca attctttgac
    10981 tgcacttctc acttcttcta atacagcctc attttctgca tttttaaggg ttttaatgat
    11041 gagttcagcc actttgcgac tttcttcttc accaaatcca cgtgcagtaa tggctgctgc
    11101 tccgatacga atcccacttg tcttgaatgg tgacaaggtt tcgtaaggga ttgaattttt
    11161 atttagggta atattgactt catccagcaa gttttgagca acttttccgt tttctacaat
    11221 cttagtcaca tcaacaagga agaggtggtt ttcagttccg ccagaaataa tacggaaatc
    11281 aggggcttgc aagaagacat ccgccatagc cttgctgttc ttgataacat tggcagcata
    11341 ttccttgaag gctggatcca aaacttcttt gaaggaaact gccttagcag ccacaatatg
    11401 ctccaaagga ccaccctgaa taccagggaa aatagctgaa ttgattttct tagctaaatc
    11461 ctcatcattg gtcaaaatca aaccaccacg aggaccacga agggttttgt gggtcgttgt
    11521 tgtagtgata tgagcgtatg gcactgggct tgggtgaaga ccagctgcaa ccaagccagc
    11581 gatgtgggcc atatcaacca tgagcttagc cccaacagca tctgcggttt cacgaaattt
    11641 tgaaaaatcg ataatttgag aataggctga agcaccagct acaatcagtt ttggttttac
    11701 ttcttgggct tgtttcaaga tagcatcaaa gtctaagagt tccgtttcag gatcaacact
    11761 ataagaaaca aagttgtagg tttgaccaga gaagctaaca ggagccccat gagtcaaatg
    11821 accacctgct gccaaatcca ttcccataac cgtatcacct ggctcaatca aagccatgta
    11881 agccgcacag ttagcctgac ttcctgagtg aggttggaca ttggcaaatt tagcaccgaa
    11941 aatttctttt gcgcgttcaa tggctagaga ttctaccaca tctactacat cagttccacc
    12001 ataataacgg cgtcctgggt aaccctcggc atatttgttt gtcaagatag acccttgagc
    12061 tgccataaca gccttggaaa ctacgttttc cgaagcaatc aactcgatat tgttttgttg
    12121 gcgttcttct tctttggcaa tagcattcca gagatcagca tcgtatgctt taaaatcatc
    12181 tttatcaaaa atcataggtc ttctccttta ttttgtgact agtccattag tttgatttta
    12241 caataagaaa ataaactaaa agatgcgaat aaaccgtttc tgcactttat cacaagtata
    12301 accaactttt tcataaaatg catgagctcc cagacgatga tcggcagagt ttaagcagat
    12361 aaacccataa ccacgtcttt tggcttcttg ttccaaccct tgtagtaaac ttttaccaat
    12421 accttgacct tgcgcttgag gtgaaattgc taaggctaag atattaaatc ctgctttgga
    12481 atagagtgat tcgtaaactt cagcgtggac atatccaagt aaaacatgac tagctgcatc
    12541 ctcatagcca agaaggaaat gatgggaatc ctgagataat ttagctagtt gactagctgt
    12601 gtcctctgga ctaaaagaat aacccaaagc ctcttggtta atttcacaaa tggctttcac
    12661 atcagtttct cttaaatctc ttagcatctc attcctcctc aaaagaaatc tctggcaact
    12721 gagcaagaat atcttctcgc ttaatggccc cttggcgtaa gattttcacc ttgtctccag
    12781 acaaatccaa aatagttgaa tcctgtccag ttagaaaagc atcgtcttcc agacccagaa
    12841 cttcttggtc aaaatccttc aaaatttgtt caaaggttac accacttgtc tgacctgaga
    12901 tattggcaga cggcccaatc aagggacctg tctctcgaat taaatccagt gtgatagggt
    12961 gactgggcat ccgaaatcca acagttgcaa ggtcagaatt tacccaatag ggaactcggt
    13021 cattggcttc gagaataatg gtcaaggggc ctggcaaaaa ggtctctaca agtttttgta
    13081 gataagctgg ctgattcttt gaaaagtgca agatgtcctc taaagaggca acattgagat
    13141 tgagcgcctt gtctctagga cgacgtttga gctggtaaac acagtcaact gctttttcgt
    13201 ctagcgcctt ggcaaaaaga ccataaaccg tctctgtagg tagaacgaca gctccaccat
    13261 tttccaactc ttgtctaatc ctgtccatca tcaaccacga ccatcctatc ttgaccaaat
    13321 tggtccttga gtgttcgaac tcttttttca ggaagatgtt tcttaaaaag cgcaggaaca
    13381 ctttgacctt gcttgtatcc aatttcaagg taaatcttac caccatcttt gagatagtct
    13441 tttgcatctt ccgcaattct acggtaaata gctaggccat cctcgtctgc aaagagagct
    13501 agatgaggct ccgaatacaa gacattcaag cctacctctg actcaccttc acgagagata
    13561 tagggtggat tggaaacaat tatatcatat ttttcagaaa tttctgtaaa acagtcagat
    13621 tttttaaaaa atatttgaag attttgattt ttagcatttt ctgatgcaag ctctaaggcg
    13681 tcttgggaaa tatctgctgc tgttactgac caagctggtc tgttttttgc taatgctaga
    13741 gctatggcgc cacttccagt cccgatatct aggacctgaa gattttcctc aagattttca
    13801 gttagaataa gctccactaa ctcctctgtt tctggacgag gaatcaaaac ccgttcatcc
    13861 acctttaaat gcattccata aaaatctgcc tgtccaatga tgtactgagc tggcttgtga
    13921 gttgctagtt gctggtaaat atcttctaca aattgttttt cttcctctgt tgtcacctcc
    13981 tgctggaggg caaaaataaa gtctgtaaaa gatagatttt tcagactacg atagacaaaa
    14041 gagaggcttt ccgcttcctc tccttgtctt atcaactctt cttcaaaatt tgaaaataat
    14101 tgagctaatt tcattatttg tttaattctt ctagtttttg tgtttggtca taaagcacca
    14161 aggcatccac aacttcgtcc aatttaccag acaaaatcgt atctagtttt tggagggtca
    14221 agccgatacg gtggtctgtg acacggtttt gtgggaagtt ataagttcgg attcgttctg
    14281 aacggtcacc agtaccgatt gtcgacttac gctcagcgtc ctgctcatct tgagcaatct
    14341 gagcaaagtg gtcagcaaca cgggcacgaa tgattttcat ggccttctca cggtttttct
    14401 gctgggtacg ttcttcttgc atctcaacct tgatattggt tggcaagtga acgatacgca
    14461 cggcagtcgc aaccttattg acgttctgac caccagcacc tgatgcgtgg taaatatcaa
    14521 cacgaagatc ttttggatcg atatcgtatt ctacttcttc gacttcaggc atgacaagaa
    14581 ctgtggcagt tgaggtatga acacgacctt ggctttctgt cacggggaca cgctgcacac
    14641 ggtgggcacc tgattcatac ttaagcttag agtatacaga ctgacctgaa accatagcaa
    14701 ccacttcttt aaaaccaccg acaccattca tagaggcttc catgacttca aagcgccaac
    14761 cttgggcttc cgcatacttt tggtacatag ttagcaaatc tccagcgaaa agtgccgctt
    14821 cgtctccacc agctgctcca cggatttcaa ggatgatatt cttgtcatcg tttggatcct
    14881 ttggaaggag caaaattttc agtttttctt catattcttc tttttcagcc ttggcatctt
    14941 tgagttcttg cttggccatt tcttccaagt ccgcatctcc gcctgattcc ttaatcatct
    15001 cttcggcatc gacgatattt tgaaggactt gtttatactc acggtaggct attacggtgt
    15061 cacgattgga agcttcttct tttgaaagct ccataaaacg cttggtgtct gaaacgacat
    15121 cagggtcact cagcaattct cctagttctt cataacggtc ttctacagct tgtagttgat
    15181 catagatgtt catttttctt cattctcctt attgatttca ggggcaaaat aatgtttacg
    15241 acaaaccgag atataggttt cattaccacc aatctggatc tgttctccat cgtaaacggg
    15301 cagtccatcc tgtgttcgca acaccatggt cgcctttttc ttgcaatact gacagatggt
    15361 cttgatttcg tcaatcttgt ctgctaaaag caagagatat ttggaacctt cgaacaattc
    15421 attgcgaaag tcatttttca agccaaaagc catgacgggt atgtctaact cgtctacaac
    15481 acgagctagg tcataaacat ggtggcgttt gagaaactgg gcttcatcga ccaaaacaca
    15541 gtaaggtttt tctggtaggt ctcggatata gccaaagata tccgttgttt cctcaatcgc
    15601 aagggcaggg cgtttcatgc caattcgact cgacacatag ccaacaccgt cacgcgtatc
    15661 cagagccgag gtcataatca caacaccttt tccttgctcc tcgtagttat aggccacttt
    15721 gagaatctca atcgttttac cagagttcat ggtcccataa cgatagtaca actgtgccat
    15781 gtttcttgct tcacgtccat ttctaaattt ttgctacatt ctagtatatc ataattttct
    15841 taagctttaa acggcaaaat gtggtaaaat ggaagaaatc aaaactagtg gaggaagcta
    15901 ttatgccatt tgtacgcatc gatttatttg aaggacgcac gctcgagcaa aagaaagctc
    15961 ttgctaagga agtaacggaa gcagttgtcc gcaacactgg agcccctcaa tctgctgtcc
    16021 atgtcatcat caacgacatg ccagaaggaa cttacttccc acaaggggaa atgcgtacta
    16081 aataagctag cttaagcaga attgcttagg ctttttcaat ctccaagtag cattcattga
    16141 agaaatatcc taaatttgtt acaatttgaa aagaaacttg gagaatttcc aagaaaagag
    16201 ctattaatta aaggaaacat tatgattaca cgtgaatttg ataccatcgc tgctatctct
    16261 actccactag gtgaaggggc tattggtatt gtccgcctga gcggaacaga cagttttgct
    16321 attgcgcaaa agatttttaa aggaaaagac ttgaacaagg ttgccagcca cactctcaac
    16381 tacggtcaca ttattgatcc tctgactggt aaagtcatgg acgaggttat ggttggggct
    16441 atgaagtctc caaagacctt cactcgtgag gatattatcg agattaacac ccacggtggg
    16501 attgcggtga ccaatgaaat tctccagcta gctattcgtg aaggggctcg gttggcagaa
    16561 cctggtgaat ttaccaaacg tgctttttta aacggtcgcg tagacttgac acaggcagag
    16621 gctgtgatgg atatcatccg tgccaagact gacaaggcca tgaacattgc ggtcaaacaa
    16681 ttagacggct ccctttctga cctcattaac aatacccgtc aagaaatcct caatacactt
    16741 gcccaagttg aggtcaatat cgactatcct gaatatgatg atgttgagga agctactact
    16801 gccgttgtcc gtgagaagac tatggagttt gagcaattgc taaccaatct tcttagaaca
    16861 gcccgtcgcg gcaaaatcct tcgtgaagga atttcaacag ctatcatcgg acgtcccaac
    16921 gttgggaaat ccagccttct caacaacctc ttgcgtgagg acaaggctat cgtaacagat
    16981 atcgctggga caacacgaga tgtcatcgaa gagtacgtca acatcaatgg tgtacctctc
    17041 aaattgattg atacagccgg tattcgtgaa acagatgaca tagtggaaca aatcggtgtt
    17101 gagcgttcga aaaaagccct taaggaagct gacctagttc tgctagtact aaacgctagt
    17161 gaaccactaa ccgcccaaga tcgccaactc ctagaaatca gccaagatac caatcgcatt
    17221 attctactta ataaaaccga cctgccagaa acgattgaaa cttcgaaact acctgaagac
    17281 gttatccgta tttcagtcct taaaaaccaa aacatcgaca agattgaaga gcgaatcaac
    17341 aacctcttct ttgaaaatgc tggcttggtc gagcaagatg ctacctactt gtcaaacgcc
    17401 cgtcacattt ccctgattga aaaagcagtt gaaagcctac aagccgttaa tcaaggtctt
    17461 gaactaggga tgccagttga cttgcttcaa gttgacttga cccgtacttg ggaaattcta
    17521 ggagaaatca ctggagatgc tgctccagat gaactcatca cccaactctt tagccaattc
    17581 tgtttaggaa aataagaaaa atccatgatc cttcattcgg tcatggattt tattgtcttt
    17641 attagtaatc tggtcttaag acccctgtta cagttgcctt agttgcttcg tagtcgccat
    17701 ctacgacaac cttgataatg cgtttggcat cttcttctgg tgctggaaca agaggtagac
    17761 gagtgggtcc agcttcaaat cccatatagt taagaattgc cttaactgga gcaggacttg
    17821 gataagagaa gagagcatta accttaggaa tgaatttacg ctgaattgct gcggctttct
    17881 tcatatcgct ttctgcaatg gcagtaaaca tctcgtgcat ttcatcccca tttgtatgag
    17941 aggcaacaga aataacccca tccgccccaa ggttcatggc atggaaagca tctccatcct
    18001 cacctgtata aatcaagaac tcttcaggct tgtgctcaat caagtaagcc atattagcca
    18061 aactagtaca ttctttgaca ccgataatat ttggatggtc agccaaacga agcatggttt
    18121 ctggagtcaa ttcgacaact acacgccctg gaatgttata gataataatt ggtaggtcag
    18181 aagcatctgc aatagcctta aagtgctgat acatcccttc ttgagaaggt ttgttgtagt
    18241 aaggaacaat agcaagccca gctgcgaaac caccaaattc cgctacttct ttgacaaact
    18301 caatagagtc acgcgtatca ttagtaccta cacccgcaat caaaggaacg cgtccattga
    18361 caaccttttg tacagccgca aacaactcca actcctcatc gtgggtcaaa gttggactct
    18421 cagcagtcgt tcctgcgaga agaattccat ccgtatgatg ggccaataaa tgctcaatca
    18481 aggctggaat agcatcaaag ttaatggaac catcctcatg gaagggggta ataaaggctg
    18541 taatgatttt acattctttt aaatcttgat aagacacgaa aacacctctc tatttcaaag
    18601 aaggagttca tctgaactcc taaacgatat gactatttta attcaaattt caattcggct
    18661 gttggacgaa ccaatccacg ttcatgaaga gtttcagcaa tctgaactga gttccaagca
    18721 gcacctttga gaaggttatc tgaaacaacc cacatgtgaa ttcctttttc tgcatccaag
    18781 tctttacgga tacgaccaac aaaggtatca cgcgaaccaa ctgcattgat ggcttgagga
    18841 tagatttgat gagctacatc atcttcaaga acagcacctg ggaaggctgc gatagctgct
    18901 tttacttctt cgattggagc cacttctttt gtttcgatat aaacagactc agagtgagct
    18961 gacaagactg gaatacgcac acatgttgca gatactgcaa tgctatcatc ttccataatt
    19021 ttcttagttt ccttggtcat cttcatctct tcgtaagtgt aatcattgtc agtgaagaca
    19081 tcgatttgtg gaagagcatt gaaggcgata ggataatgtt tcttgtcacc gcctgaaggt
    19141 aagatttccg catgcaaatc acgtggtttc actccatcat tcaagacctc acgaagttca
    19201 cgttgtgtct caagaattgc tcccatacca gcacctgaaa cggcttgata agttgaaaca
    19261 atgatacggt ccaagcccca tttttggcga accggttcaa gagccaccat catttggatt
    19321 gttgaacagt tagggcaggc aatgattccg ttgtgggcat caagtgcatg agcattgacc
    19381 tctggaacaa ccaaaggaac atctggattt tgacggaaat aagatgtatt atccactact
    19441 accacgccag cttttactgc gtatggtgca tacttagctg atgtcgaacc acctgctgaa
    19501 aagagagcaa tatcaactcc ttcaaaagct gtttcagtcg tttcttcaat cgtaatatct
    19561 tgatctttaa atttcaatga cttacctgct gaacgtgcag aagcaaggta acggatttta
    19621 tcgattggaa gtgttgattc ttccaacatt tttatcatct gagcaccgac agcacctgtc
    19681 gcgccgacta cagcaactgt atatcccata aataacctct ttcggaattt tctaaaaatt
    19741 tctataatag aagtattata ctactttttc catgaattgc aaagcttttt catcattttt
    19801 tggaaaataa aaatcccagt cgctagacta gggattaaga ggcatcttca tgtgatgagc
    19861 aggttcacac aactcatcaa ggtccgctcc tgcgttatga cctccttatg ctcaatagta
    19921 gcccgaagac tacctatcga ctcatcgcat ctactattct actaaagaga atgactttgg
    19981 tcaacagacg aaactcttta tactcttcga aaatctcttc aaacttcgtc agcgtcgcct
    20041 tgccgtatgt atggttactg acttcgtcag tttcatctac aacctcaaaa acatgtttta
    20101 agctgacttc gtcagttcta tctacaacct caaagcagtg ctttgagcaa cctgcggcta
    20161 gtttcctagt ttactctttg attttcattg agtattagtt ttatttacac aggtgcataa
    20221 gaaatatatt ggaaaaattg ggggcagaca taacaaaaac ccttgtaaat caagggcttt
    20281 tctgtctatt taatgctaat tgccgggatt gaaccggcga cctcatcctt accatggatg
    20341 cgctctgcca actgagctaa atcagcttac ttaagaagta tactatattc agaaaaactt
    20401 gtcaagtttc cttagaaatt ttccatagga aaaagccagg taagaactac ctagcttatc
    20461 ttcttctatt tacttaaatc aattcgacga ccaattttac caataataat cgctccaata
    20521 atcaatgaag caaattcacc gattcctgtt gtaaaccaag taaggaagaa tggtaattct
    20581 gctacaatat ttaactctgc agcgatagta aacatggaaa ttgaaaagag gattgaaaag
    20641 aagaaatgat cttttcgaat caatccgtta aagaggtaat ccttgctata ttttgcaaaa
    20701 agccaaacac ctaaactgag gaatactaag gttgaaccac caccaacaaa gacatctagc
    20761 agtccgaagc taaagaaatt agcaatcata caaccgatgg taactccgat gatgtactta
    20821 ggattgtaaa aagccataaa gttcatcatt tctgaaatac gaaactgata agcaccatag
    20881 ctgatggcat ttagaggcgg tgtgacagtc aaaacgacgt agatagcagc gacgattgca
    20941 atatctgcaa catcacgaat agttaatttt ttcatctttt ctcctttggc ggttgcccgc
    21001 gtgtaatatg cttggtgaaa gaagctaagc accaagggtt gctttattca accctactag
    21061 tatagcacaa tagcctgctt tatgctatac ttaacacatg aaaattccta ttcaaaaatt
    21121 ttttaacaat gaaatcttag cctatctctt ttttggcctt gcgacaactc tagtttcgat
    21181 tctctcacga ctagtcattt atcaactaag tcatcaggaa ctcctggcta ctgccctagc
    21241 aaatattatc ggtatcctat ttgcctttat cacaaatgat acgattgtat ttaagcaaaa
    21301 aaagaaaaat agacttatcc gtttagtgaa attttctctt gctcgccttt ctacttttct
    21361 gttagacttg tttttaactt ttctctttgt aacccaattt cctcacatca tagggcaatt
    21421 cgtaactgaa aacattgata agataaatgc tattgaaaca ataattgcac aaatactcat
    21481 tattatcatc aattatatct tgagcaaaat ctatattttt agaaaataat gctccattta
    21541 tgagcctttt aattgccttc tataatgatt taggatacaa tgaaacacga aacattgaaa
    21601 ggaaaacagt atgttaaaaa atctaaaatc gttcttgctt cgaggaaatg ttattgacct
    21661 tgctgtcggt gttgtaattg cctctgcttt tggtgctatc gttacttcac ttgtaaacga
    21721 cattatcact cctcttattt taaatcccgc tttgaaagct gctaaagttg aacgtatcgc
    21781 tcaactttct tggcatggag tcggctatgg taacttctta agtgctatta tcaattttat
    21841 ctttgtgggt accgccctct tctttattat caagggcatt gaaaaagcac agaaactgac
    21901 tggcataaag gaagaaaaaa ctgccgaaaa aaaaccaacc gaattggaag tccttcaaga
    21961 aataaaagct ctccttgaga aaaaataatc gattaaaagg atctagcgca aagctaaatc
    22021 cttttttctt tactctttgg gtaacttgcc tgctttttca agcatttttt tgataagata
    22081 aggcatctta acattctccc gccctttttt ctcaatcagt tttttcacaa attctggcat
    22141 ttgtaaatct tcagattcag ccaaaatgtt tttcgtctcg tctgaaggaa ctaactcatc
    22201 aaaggtctct tcttctggta gaaattcctt aaactcttga ttttcattga ctctaattgt
    22261 attgaccaaa gcatcaatca aacgagaatc tgtatttggc attggtggac gatggtagtt
    22321 taccccaaat tcctgacata agtcataaca ttccacatca ttgtcaaaca agacctcaat
    22381 atgctcactg atgaaactaa taggtacaaa aatataatgg tctggatgtt ctgtctgttc
    22441 tctgagatac tccaaaacat ctggtttaat ccatggaata ccaatatcac tctcactctg
    22501 ccaagtgttg gtatattgtt ctgaactcaa gcccagtttt tcagcgacta gcttgctatt
    22561 ttcgaaaatt tggtctatat aaggatcacc aaagtccaag gcaaaaatag gcacactatg
    22621 ggctgaaaag atgactttaa agctgtcttg ctttacttct tcttctaaaa tcttagcaat
    22681 ttcatctgcc caatagttta agagcgcttc ttcctgatac cagtccttaa tgaccaaaaa
    22741 ttgaatttgt ttgctttcta aaaatttttc atagcccatg acagagtaga aagaataatg
    22801 gggctccaaa atcaagcaaa tacactgttc aattccgtct gcttccattt gaccgatcac
    22861 atctggaata aagggactgg aaaacttatt agcaaagtag acactgtatt cattccccag
    22921 cctatcttct accaaggcaa cctcttgacg ggtaattttt tgcagaggcg tgcctccaat
    22981 tcgtacataa ttatcataga gagtctgaat ctcgtggtct tggggtctca ccccacgacg
    23041 aatatttgtg aaaaaatcag ctacaccttc aaaggtaatc tcttctggtg aaccgaaggt
    23101 catcattaaa attgcttttt tcatgactgc ttccttgtga tgtttttatc aagtttattt
    23161 tatcattaat tcatcgataa gtaaacgcta acatagggac attctcaatc ttctgtcttt
    23221 tgtttttctc ttctttctat gatacaatgg aaaaaataaa ttcaaaagga gtttttttat
    23281 gacttatcca aatctcttgg accgcttctt aacctacgtt aaggtcaaca cgcgctctga
    23341 tgaacactct actactactc caagtacaca gagtcaggtt gacttcgcaa caaatctcct
    23401 aattcctgaa atgaaacgtg ttggactgca aaatgtttac tatctaccga atggttttgc
    23461 tattggaacc ttgccagcca acgatccgtc tttaacacgt aagattggtt ttatatcgca
    23521 catggatact gctgatttta atgctgaagg agtcaatcca caggtaattg aaaactacga
    23581 tggtggtgtg attgaactag ggaattctgg tttcaaactc gatccagccg acttcaagag
    23641 tcttgaaaaa tatccaggac aaacgctcat cacaacagat ggaacaacct tgctaggtgc
    23701 tgatgacaag tcaggaattg ctgaaattat gacagccatt gaatatctaa ctgctcatcc
    23761 tgaaattaag cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa tcggtgttgg
    23821 tgccaataaa tttgatgcag aagattttga tgtggatttt gcctacactg ttgatggtgg
    23881 tccactaggt gaacttcagt acgagacttt ctcagccgct ggtgctgaat tgcatttcca
    23941 aggccgtaat gtccaccctg gtactgccaa agggcagatg gtcaatgccc ttcagctagc
    24001 aattgatttt cataatcaac ttccagaaaa tgaccgacct gagttaactg aaggttacca
    24061 aggtttttac catctaatgg atgtgacagg tagtgttgag gaggcgcgtg caagctacat
    24121 cattcgtgat tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc aatctatcgc
    24181 tgataagatg aatgaagaac ttgggagcga ccgtgtcact ctcaacttga cagaccagta
    24241 ctacaatatg aaagaagtca ttgaaaaaga tatgactcca attaccattg ctaaagccgt
    24301 tatggaagat ctaggtatca cgcctattat cgaaccaatc cggggtggaa cagacggctc
    24361 taagatttcc tttatgggaa tcccaactcc gaatatcttt gcaggtggcg aaaatatgca
    24421 cggacgtttt gaatacgtta gccttcagac tatggaacgt gcagttgata ccatcattgg
    24481 catcgtagct tataaaggct aaaaagacga ggtggctcag ctacttcgcc tttcttttta
    24541 ttctactggt ttttcttgat ttccagtagt tgtagaagat tctgttgttt cattttctga
    24601 agttgattca gcaggtttag aatctcttgt attgcttggt ttgttttcgt cgctaccagt
    24661 ttcaatgtta gattctgcag ttgcgtttgg ttggttctca gcactggtgt tatcaccatt
    24721 tgcttcagca tttcttgctg gacttgtttc ttcacttgcg ctagcttttg actggatttg
    24781 atgattcaaa actagaatag cttttgtcga ttcaagtaaa gctgttttgt ctttactctt
    24841 agcagaaagt tgatctaata atgcatccac cttatcaaag tccgcatcag atccattatt
    24901 actttctaaa taagagtgaa gcgacatgag aatatcgtag agtttttgat agagtacaag
    24961 tgtctgagga tcttgctcag cattttcctt ttcttgttga agggcgctag cgatacgagt
    25021 caagacatct tttacctgac tgtttacttc atccaagtct gcatcagcct tgtttgtggc
    25081 agcttttaga ttttctactt cttctgccaa ggattttctg attccttctt catggatttg
    25141 ttccaagagt tgatttgcct tgctcaaaag actttctact tcttccttgc tatctgtcgc
    25201 agattattgg ttgccatcta ccatgtactc ctaaaacagg agagttataa tccaagatta
    25261 caaggcctta cagaaataag aaatccagat aagacaatgt tcgtccaaga cgctattcgc
    25321 ttcgcacagc agcacggatt caatatgctt taattttaaa gtttaggtgt caagacctct
    25381 ttttagtgtg cccaaaattt agagaagtaa tcaatcaact aacttttatt tttttcaaac
    25441 tttcagtaaa ctgacctaaa gctaactcaa tctgtctttg ttcgataggc ttgtctttgt
    25501 agatgcttct gctatcagct agaagttgat ctacttttgc caagactgcc ttctcatcaa
    25561 aagttccagg ttgatagttg gattgcaggg atggaatctt gtttttcaaa gccgcttcat
    25621 atcccttagt ttgaaccttg atgtagtgat tgtggtcgcc atgaggaatc acaaaacctt
    25681 ctgaatcttc acttataatt cgattggcat caaaaccatg accatcttct tcctcatggt
    25741 ggacatgtag tgacggatta cttaatacag aactagaaga acttcctacc tcttccgtgt
    25801 tagagtgtga tgggggattg ttaagagatg acttaggaat atagtgatag tgatccccat
    25861 gtcttactat ataagcatca cctgtatctc tgacaatatc attagggtta aagacataac
    25921 catcatctac tgcagaaaca ccattattcg gtgtcaccgg caaagattga ctgagagctg
    25981 tagtattccc tgataattat acttttgcga ctgctaattc acctgccgac aagtcactct
    26041 caggaatgaa atgatagtga ccaccatgtg gtactatagt agattgaaat agaatatgag
    26101 caaattgata aggagatttt aaagtaattt ctagcaatga tttagaaact atgatgtgct
    26161 attctaaatt caactcacta tatataacca tcatcggtag tataacgtcc ctgtaatttt
    26221 gctacagata cttctgcact agctccttta tcgtctttac catgttcttg tttttggcga
    26281 ttgatttcat cttttgttcg tacattttct gcatgagctt gatctttaag gtaaacataa
    26341 tactttccat ctaccttaat aatatatcct cccttaacct aactgacgat atcttgatct
    26401 ttcggctgat agttgggggc tttcattaat agctcttcac taaagagcgc atcaaaagga
    26461 actttatcat tatagtagtg ataatgatcg ccatgagaag ttacataacc ttgacctgta
    26521 atcttaataa caatttgttt tgcttgaatt ccttcttttt gactaaccta gtctggagtc
    26581 aaattttcag tcttcttagt gtctttatta ctgtttacat atgaaacacg atttttatct
    26641 gtattggcct gttagctatg ttggttcaga gcataaacac acagacttaa ggaaaggata
    26701 acaacagatc cagctgctat atatttcttt ttaaatttca taattacctc atttctataa
    26761 ttatttatat gatgtcttca ttattaaatg attaaataaa ttgattaacc aattaattaa
    26821 ctagtaaata ttccacctct ttttaagttg tatgtcaaga gattttatat attaataata
    26881 aaatgaaatt ctcccaaagt cagagtttta tttctaactt ttgaaagaac ttcatttttg
    26941 attcagactt tttctactgc tattccttac gctatgagat cagataaatt cttttttatc
    27001 acttctccac ttggcaatct taattcaatc gttccatcca tattgaatat aacactatct
    27061 aagcctaatc cgtaactagc tgtaaatttt tctacttttt cttgtacagg atctactgct
    27121 ggagcttcct ctaacgttga attactagta ctattcctag tttcagtaag tttttctttt
    27181 tctaccttct cactagtctt tggttcttct accttttcat caagttttga gttttcttgt
    27241 gctttattcc ttttaaattg tggtagaata cttggtttat cagtttgatt ttctttttcc
    27301 aagataggta cttccacaat ataagtcgat tgattgtcca aataagcatt tgccatgaag
    27361 gttacaggaa ttttatttcc ggccgttctg gttgttcctt ggtttaattt cggaatcggt
    27421 aatttgattt caccaacttt atagttattt tctaaataag catttccatg aaattcatca
    27481 aacactctga ctaaagcatc agttccttta ggcactgcaa attgagggtt cactcttaaa
    27541 taagtatccc ctgcatggaa aggatagaaa atcgtttgac tggccatttt gtaagctaaa
    27601 gaggttgaaa ctgtaaatgt accatcataa cttacttctg gataatcttt tgaagcgata
    27661 gtatacttaa atgtttgtcc tggtaaataa ggttgatcta attcaaagtt tgcaatattc
    27721 cctactcctt ctccaaatac tttaccagat actttctcca atacttttcc atctggtgtt
    27781 attaatttta ctagcatatt gatacctaat tttttctcca attcaggcgg aaaactaaaa
    27841 gaaacgcgtt tttgaccatt ggctagagta aagttttgat tattaaacgt actatttttt
    27901 aacaaattaa caacattcgt taattcttct ccagtataaa ctttattccc ttctttttta
    27961 gcaactcctt cttcgggttt aaacagttca tagttactgt gagaatgacc aattccaacc
    28021 ggtttatgtt catcaatcgg atctgcatga tggtgatctc catgcggata aataatcgca
    28081 tttttttctt tattcacgac aatactttca cgtttgacac catattgttt cataatgcca
    28141 gcaatttttt cttcgatttt tttatctaaa tctttcattt ctttggcatt acctgaataa
    28201 tcctgttcat gagattgcaa agaatctaat ccattatgac tagttttaac ttcctctaaa
    28261 tgtttttgag cagccttaat ttgatcagct gtcaagtcct tcttgaagaa gtaatgatta
    28321 tgattaccgt gactcatgat aaatcctgat tcatcttcag caataatacg attagcatca
    28381 aagccgtgcc catcttcttc atgttcctca tgtgaaacat caggattgac tggaagagat
    28441 ggcgaaggtg ttgttagacc attatttgga agagtcggtt gtccaatttg attcgactta
    28501 ggaatatagt ggaagtgatt gccgtgaggg acaatataag catcacccgt gtcctcaatg
    28561 atatcagatg cattgaagat atacccatca tccgttgtat aacgtccttg agctctggca
    28621 gcaactactg ccttatcgtt agaatcgaca ccgtgattac tactatgttc ctgtttctga
    28681 cgtttaatct cttcttttgt ccgaatatta tccgcatggg ccgcatcttt aaggtaaaca
    28741 tagtattttc cgtctacctt aatcacatag ccacccttga tttcattgac aatgtctgaa
    28801 tccttcaact gataattcgg atctttcatg agaagttctt cactgatgat ggcatcataa
    28861 ggaaccttgc cattatagta atgataatgg tctccatgtg aggtcacata accttgagcc
    28921 gtaatcttga taacaatttg ttctgcgttg atcccctctt tcttactgac ttcatctggt
    28981 gtcaaatttt ctgccttttg accagcctga tcaccatcta tataagcaac tcgattagac
    29041 tctttcttag cctgaccagc ttggtgacga ccaagttcat aggaacaaac acttagggca
    29101 aggactgcca ctgaacctgc tagatatttt ttattgattt tcataaatcc ctcatttcaa
    29161 taaatgatga agctttttct caacttcttt tacttgatta aatagttttc taaaccggtt
    29221 atttaaccag taaatggttt actatttaaa attacttttg tcaagtttct gttacgtttt
    29281 tctaaaaaag agaagcaaca cgaaaggtta cttctccata aaatatgctc cattcatttt
    29341 actactgtat aggagtcggt ttactttctt ttaacaaagc aaagagacta tctacttctg
    29401 ctaaaatagt gttattgtct ttcgttccga gaagaagact gctttgtaga ccagccaatg
    29461 tctccatagc attttgttga atacgagaat ctgttacttt cgcaagtaaa gcctccgcct
    29521 ctgttatctt aacttcaata atagaacgct ctacttgagg aacttcagct tcttctgtag
    29581 tatcttcagc ttcttcctct gtctcttccg tatcagtgct tggtttataa agattatctg
    29641 ctgaaggatt taaacctgcg tgattctctt cttcatcaga ttcagggcga gttggctcac
    29701 ttacttcctc atgttcctta ttttcatcag gtttactgtc ttggtctgcc tgatgcttac
    29761 gaacatggtc gctagcgtta ccccaaccat tatctgagtg aggacgttgg tcaggatgtt
    29821 caacatagta tttcactgtc gcaaataaat cttctaaagt atacccttca ggagctgagt
    29881 aaagcccttc atcaaaccat gcaaacttaa ggttatgata gtgatcaaag tgaggaatta
    29941 taaagtgacc attttgtaca gctacagtat actgtaaatg attcggtatt ttttctaatg
    30001 gtaccttttt ctcagctttt acgcggttat agatagcttc tgtccctgtt gcctctgttt
    30061 ttgcttctgt tgcttcagta gaatttggag cttgtaagcc tttttcttta gcataagcct
    30121 gagctgctgc tctttcagct tcagataagc tgtctttttt aatccagtgg ctatggttca
    30181 agtgtggagt gacgtaggca tttccttcat cactttcaat atcatgctca tcaaagatat
    30241 agccatcctc tgttgtatat ttacctgcta atttcgctaa tttaatttca tcgtctgtat
    30301 aagcaatctg agcatttggt ttgccaagtc gctctggatg agtaattggt gctaggaatg
    30361 tcaataaatc atctaccaat tttactttat tagaagattc attattcaag cgttctgcta
    30421 atttgtctaa ggcatggaaa tcagaagtac gccccttatt ttcagacaag gctttatgag
    30481 cctgggttaa cagattgtaa gctttatcat aaaattctcg gtcacgagaa gcgacacttt
    30541 cttttttagc aactagagca tgtgtctctt gagttttctt agacaagtga ttttcaatag
    30601 catcaatctt atccttagcc aagtctttag caaaaacata gtgactgaca ccagcaattt
    30661 ccacaacata gccttctcca acttttctaa caacctgttc tactgcaaaa tcagtttgtt
    30721 ttttctcagt tgatggttga acttgcggtt ttggtgctgg tttcaaataa tgcattcctg
    30781 gcaagactgc accattttgt cccttgatag ctatcatacg agccaatttt tcttccaaag
    30841 gtgacatttg tgaataaggg ataaagtgat aatggtctcc gtgcggtaca gcaacaccat
    30901 tggctgtacg atatgctatt tgtgccggat caaatactag gccatcagat tctacatggc
    30961 gttctgataa gggtttagca tacaattcac gtaaaaggct tgaaatgttt tccccttgat
    31021 tttgatgata agttggagtg acagtcagat tgtggttctc tgacaatctt ggttgagctg
    31081 gatttgcatt atgactagaa cttgaagaag gacgagatcc ctgcttccca ttccaatagg
    31141 cttgggcagc agctaattca ctggcagaca aatcactctt aggaatatag tggaagtgat
    31201 tgccgtgagg gacaatataa gcatcacccg tgtcctcaat gatatcagat gcattgaaga
    31261 tatacccatc atccgttgta taacgtcctt gggatctggc tgcagcaaca gcattatctg
    31321 ctcttgagtt atgattatga ctgcgttcct gcttctgacg tttaatctct tcttttgtcc
    31381 gaatattgtc cgcatgggcc gcatctttaa ggtaaacata gtattttccg tctaccttaa
    31441 tcacatagcc acccttgatt tcattgacaa tgtctgaatc cttcaactga taattcggat
    31501 ctttcatgag aagttcttca ctgatgatgg catcataagg aaccttgcca ttatagtaat
    31561 gataatggtc tccatgtgag gtcacataac cttgatccgt aatcttgata acaatttgtt
    31621 cggcgttgat cccctctttc ttactgactt catctggtgt caaattttct gccttttgac
    31681 cagcttgatc accatctata taagcaactc gattagactc tttcttagcc tgaccagctt
    31741 ggtgacgacc aagttcatag gaacaaacac ttagggcaag gactgccact gaacctgcta
    31801 gatatttttt attgaatttc attctttcct cactttaatt cttctgctag aatactcata
    31861 ttttcttcaa gattttctaa ataggtcttg tcattttgtg ggtctgactc taaaggattc
    31921 agagttttaa gacccacacc tgttgatttg acaagagttt cagctacttt tgaagaagcg
    31981 ttactttctg taaaaatcgt tttaacctta taggtcttaa caaattcctg aatttctgtt
    32041 agttgtcgtg gacttggttc ttgttcagga gagatacctg caataccaag ttgattgagt
    32101 ccaaatctct tagctaaata agaaaaggct gtatgttgtg ttacaaatgt tttctgagtc
    32161 gctttttcaa atttagactg gaatttctta gtcaattcct gagctttttt gataaaggct
    32221 tgcgcatttt tctggtaagt ttctttatgc tcactatcca cctctgaaag tttatcagcg
    32281 ataatctgag cttcttcgcc agctttttca ggatctagcc aagtgtgagg gtcatagagc
    32341 gttttttcat caactccatc ccctgcttct acatcttcta gccctgggac acggtctaaa
    32401 gtcattccct ctgaagcctc taagaccttc actttagatt tttttagatt gggatctaaa
    32461 cttcctgccc aagattctag cgtatgagaa tggtaaacaa agacatctgc atcatagatg
    32521 gccgcgatgt catttgccga aggttcaaag gagtgaatcc cactactcga ctgaatcatc
    32581 cgaacatcat tcaagtcacc agaaacctcc ttgaccatgg catagatagg ataaaaactg
    32641 gtcacaattt tcatcccttt cccagtctgg ctttcttttt gaccacaagc tcccaagcat
    32701 acaagaaaga tacttaacaa gactaaaaat aaattttgtt tcttcatgaa caactcctta
    32761 accatttaat taactagtaa acattctact cctaaaaatt taatctgtca agatattttt
    32821 agaaaaaaat tgaaatttct ttcacatata aaaatctgct gagtttcaac aactcaacag
    32881 acttccactt tattcttcta tggttgaatg cttatagcca taagtaaagt aaataagact
    32941 tcctatcaac aaagcaacga ggaaagcaat ccaggtttcc atattatact gcaacatgaa
    33001 ggatagacaa atgatgattg ataaaatggg taacagaggt accaatggtg ttttaaattc
    33061 cccagctttg ggcattcctt tttctttccg taagcgaatc agaccataag ccagcatgat
    33121 caagtaggct aaggtacaag tatttaagaa ggctgcaata ctagctaatg gaaacattcc
    33181 tgctgctact gctgaagcta gacctgtcaa gatagtagca ttttttggta ccttgcttgt
    33241 ttttgttaat tctttaaagg cagcaggcat taacccgtca cgcgctaaac tgtaaatcat
    33301 acgcgatagt gcataggtca tcgaaataca aactgtaatc aaggtcaaga tagccactaa
    33361 tgacacatag ttagctgccc aactaatccc aacgctacga agagcaaagg caacggcatc
    33421 atcgacattt agttgactat agtgaaccac accagtcaag acaagcgtca ccaaggcata
    33481 gagaatggtt acgatagaaa gtgataagac aatccctcta ggaatattct tttgaggagt
    33541 cttgacttca tctacagcca tagagatgga ttcgaagcct aaaaatccaa agaacatcaa
    33601 ggacgcacca gccataatac cagtactagc accatagatt tgtccaaaac cataaggagc
    33661 aaaattactc caattatcaa gtttgatatg ccaaattcct actaaaacaa agagagctaa
    33721 agccgagaat ttcagaatga ccaaaattga attaaagcgt aaggctgctt tagcattgag
    33781 taaaacaagc gatgtcacta atgccaagac aagaataggc aataaatcaa caaatgttcc
    33841 tgcctgagga ttaaaggtac catttaaagc ctgaggaagg gctatcccgt attgagagag
    33901 caagccttta aaataagctg cccaacccga agccacacct gatatggctg tcatgaactc
    33961 catcatggtt aaccagccag ccaaccaagc tggaaattct cctaaaatag catagagata
    34021 actgtaggca ccacctgtag cgggtactcg cgaggcaaat tctgcaaaaa atagtgctga
    34081 taatcccaca cataaggcag aaataacgat tgaaatcact agggctggac ctgctagagt
    34141 tgcggctgca gtacctgtga ttgtaaagac acctgtccct accatggctc cgatacccag
    34201 caaaatcaaa tcccataact tcaaatgcct gtgcatctca gttttatcca aacttacatt
    34261 ctttgttcta aatatattca tctttgacct ccaaaataaa atgatgattc tattttacca
    34321 taaatatagg agatatgtga atatttataa aatgtttttc taaaaaaatc tgactacatc
    34381 ttgtaatcag attttatcga ttctagttca tttctttaaa tgctgcttct gcatccgcgt
    34441 tgctgataac accaaattga atctttccaa tcttttcttg actatcaatc aggtattctg
    34501 taggaatgct tcgaatttga taagcttgga aggttgttgc tttggtatca taaagaactg
    34561 ggatatcctt ataaccttga tcttggaacc attgtgggaa ttgttcgaca gttttttcac
    34621 cttgaattcc tggtgcaatg acagtaagaa tttcaaaatc gcgatctggt tttgcagcta
    34681 attccatcaa ctcaggcata cttttcttac atggaccaca ccatgaagcc caaaacttca
    34741 agtagacttt tttaccctta aaatcagata acttcacttc tttgccatcc atggattgca
    34801 atgtgaagtc tggagcttct tttccaacag caatttgttg tacaggcgtt tgttgctgtt
    34861 gttttgggga ttgttctggt gcttgagtct ttttagcctc ttcttcacca caggccatca
    34921 gtacaactaa tgacaagagg cttaaaccag caaacattac ttttttcatt tgttctcctt
    34981 tattcaaaaa ttcctgctag aacattgact tgtcctaata gtaacaaaat tcccattaaa
    35041 ataatgagga aaccaccaat tttcttcagt agcatcatat gacgcttgag tttactaaaa
    35101 taaggcatca ctatgcctga agctagagcc aagaccaaga aaggaatggc catgcccaga
    35161 gtgtaaataa gagtatagat agctccttgc caggcgccat tgcctccaga agccgcaagt
    35221 gctaagacag aacttaaaac cggaccaata caaggcgtcc aaccaaagct aaaggtaata
    35281 ccaagtaaaa aaactgacca ataacgatta gaatctgatt ttttaaaggt aaaacttttt
    35341 tgaacttcta atttcttcaa atgaaaaatt tccatctggt gaagacccaa aatgataata
    35401 ataactccca tgacatatcg aaaccaattt gcatagagaa catgaccaaa gtaaccagca
    35461 ccaaagccta gaataaagaa aatgagagag atacctgcga taaagcaaag tgttcgaatc
    35521 aagcctaacc agagaacctt tctcccaaac aaagaaaagc tttttgcact ttcttgatca
    35581 tccaataaaa tcccagcata gactggcaga agaggaaaaa tacaaggaga aaaaaaggat
    35641 aaaacacctg ctagaaaaac agagattgaa aatactatcg tttccaataa agaaccaact
    35701 ttcttaatca ttctaatcct attttactat attcaatttt atttgtaagc tttctgctac
    35761 gcaaattcgt cttgaacact attggaccaa tcttttcttt tgctagtcaa ggcggatctt
    35821 atccccaaaa atagccaaaa agcaacgaca aggattactc gtcgctgctt ttgtgaacgg
    35881 aaatgtcttt taggtctgac gtttcagaaa tcacatttta cttgagttta gcaaggattg
    35941 atttaagctc ctctactagt ttagcttctg tctctgctga gccattttct tcttttacga
    36001 aatcaagggt ttcttggaga aggttttggg ctttggcaag gactttttta tccgcttttt
    36061 ctgcatctag ttgtccgaga atcttggtca attccgtact taattgctgg atttctgact
    36121 ctttcttacg gcgaaccaac cagaaggcaa tcacgcctag gaggacaagt agactgacca
    36181 caatcactcc tggtggaact gaggttgttt cagtcatctt agctgaatcc ttactatctt
    36241 ccgttccttg tttggcatcc ttcttgtcct gtgcaggctt gctgtcgcta gcatttgctg
    36301 gcacatcttt gagagagttc aaggcagcct tcacagactc tactgcagta tgcagacctt
    36361 actctgtcaa ggcacgaagt tcagaacttg tcaacttgct cttgagctgg agcttgcgtg
    36421 ctcgttgagc tagccgaagc gcttgctacc actctaggat cttgagtcgg agctgagctt
    36481 ggagctggga caggatttgc aggttgacta ggagcagtta tggtatattg aaactagaat
    36541 agtacatatt gacttctaaa acattgctaa aaatttattt gattatcctg attattttgt
    36601 cctatttctg tttcatttta ttataattga gacggttgag cacttggact agatggagtt
    36661 gttggtgtct ctgtgtctcc ttggtctggc tgagtagggg tagaaggttg cggttgaggc
    36721 gtagaaagtg gacgtgaagt tggttgtgga ttgatgttat tgatagcatc gattcctacc
    36781 acttttgcct gttctacatc cttatttgtt acgcccttgt ccaccgcaat cttagcatcg
    36841 ttcgcctctt gatctacctg ttgcaatgct cttgacttat cctcaattgt caaatcaaaa
    36901 cgattcgaaa tttctgtttt cttagcctct gctgccgcat tgatggcttc ttttgcttca
    36961 gctttcttag tagttcttgg taacgtgact tttcctatgt tagtaattcc attattcttc
    37021 gctgtgttca acgttgtttc atcttgagcg ttttctatat tttgaatagc tttatctttt
    37081 actgttttcg ctaatccttt cacttctatt tttttcatta gttaaagaat tatccttatc
    37141 tatattagaa gttttcgttg aaaatgcttg ttctacttca tttttcgccc catctttatc
    37201 taatgttgga gttgttggag ttggtattgt taccgcatca ctcatgtctg atgtagatct
    37261 ttctacatta atatttccac cataagtagc tggtatatat tctctgtctc tagctatgtt
    37321 tctagtagtt attttatctc cagcttgtaa tgcttcatcc ggtgtccaac tagcagttcc
    37381 gtttacagca gtaattgttg ctttttagtg ttatttaaat aaaattcaac aatagaatca
    37441 ttagaatttc tcgctgttga tttaactatc actcgtttac ctgcaacatt ttccaaattt
    37501 tctaccgtag acttcctgca aaactagaat cctagttcat gattggtaat accagcaatc
    37561 aaattcattc gtaatccgaa gcgtttacga tgatttcgat aggttgttga aaacatttta
    37621 aacgttttta ctttggcaaa gatgttttca accttgcttc tctccttaga tagcgcatgg
    37681 ttacaggctt tatcttcaac tgttagcggc ttgagtttgc tggatttacg tggagtttgt
    37741 gcttgaggat atatcttcat gagcccttga taaccactgt cagccaagat tttaccagct
    37801 tgtccgatat ttctgcgact cattttgaac aacttcatat catgacaata gttcacagtg
    37861 atatccaaag aaacaattct tccttgactt gtgacaatcg cttgagcctt catagcgtgg
    37921 catttctttt taccagaatc attcgctaat tcttttttta gggcgattga tttgtacttc
    37981 cgtcgcatca atcattaccg tgtcctcaga actgagagga gttcttgaaa tcgtaaaacc
    38041 attttgaaca agagttactt caccccattg gctccgacgg attaagttgc tttcgtggat
    38101 accaaaatca gccgcaattt cttcataagt gcggtattct cgcacatatt gaagagtggc
    38161 cataagaagg tcttctaggc ttaatttagg ttttcgtcca ccttttgcgt gtttaagttg
    38221 ataagctgtt tttaatccag ctaacatctc ttcaaaagtg gtacgctgaa caccaacaag
    38281 acgcttaaat catgcatcag ttagttgttt acttgcttca tcattcatag aactactata
    38341 ccatattttg tttcgcagga agtataattt aatttactag atttgatgct tctatctatt
    38401 tattcggaaa agaaattaaa aatcttccca atttctagta atattttaga agttatagtg
    38461 tagcattcca acttcaaagc actataaagt aaattgaaac aagaacaata caaacaattc
    38521 tcgtaaacgg attgcaacca caaaaaagca agcattcaca agaatactta cctatcatgg
    38581 gaggaacaac cgttcctctt ttttattact aaaattcaaa gaattccaat gcttttttca
    38641 agagcaaatc cgtatattct ggatcttctt gggatacttc tatttcccgc tgaacttttt
    38701 ccaaatcatc tgtaatcact ccatctactc ctaagtgaag agatttgctg atagcttctg
    38761 aatcattgac agtccagaca taaagtttct gatccgttgt ccatagtttg cttacaaaat
    38821 attcatccaa ggttgagtac tccatagtat atcctgtcgc tcttgtttta ggaaagacag
    38881 aattgtaggg catgatgaaa taaactggca gttcggcatc atactgtctt actttttcga
    38941 caacatggta gtctaaagac tggatttgat gtccataaat cttgagcttt gcagcataac
    39001 gggctaaaaa gcggttcatc atgtctggac tatctttttt actggtttta atttcaatta
    39061 gtaatttttg accaagttcg ttggctcgac tgagataatc ttcaaagctt gaaattttag
    39121 tctggtagcc attttcaaaa atatcaatcc ctttaagctc ctccaagttt aagtcttgag
    39181 gacttttatt gatacctgct agatttttca agttagcatc atgcatcatg acaaactgcc
    39241 catcttttgt ttcctgcacg tccgtctcca ccaagtctgg tttgagttgt gctgtagttt
    39301 ccaaggactc tactgtattt tgaatcccat ttgcattgga aacccctcgg tgagaaataa
    39361 gttgaggtag atgaaccatg ggagcctcca gataaatata accttctaag gcaaagaaaa
    39421 gactggcaca agtcatgaca ccccatcgca cgatgtgatc tttttctctc ctaggaagca
    39481 tatccagctc ctttcctgtc aaaaatgaaa caaatttaac caaaaaataa gtcagagcca
    39541 tataatagag atttttaatc acgacaaaat tcaaaatacc aagaatcaga gactctctct
    39601 gagtgatatc atctaccaaa gtttgagcca ataataaagg aatcaaagga agataaaata
    39661 ataaatgtgc tttgagcaag atgtaaaata aattccaagc ataaaaagta actctcttct
    39721 tggttttctc caagctaaac atcactgctt ctcgaacagt cagctgatca tatacaatct
    39781 tcggaagggc aaacatcaat ctgacagaga catagagaaa gataagagat agaagtagga
    39841 tgctcagcca ccacatccaa tatgtatctt ctaaataagc ttggataaac tctggaatga
    39901 cgattttatt aagataataa atcttcagca ttttccgtat aaaaggaaaa agcatagcta
    39961 tatagaaaaa gataaacaag gctttagcgc aagttagctt tttcataaat ccaaaacttt
    40021 catggaaaac cttgcggata tactcaatta gccttcgctt ttcattatag aggagatgac
    40081 gagcgccaat aaagaggagt cctatttgaa aataagcaac cagaaggtta attacaatca
    40141 aggctaaaaa agctagacta atcaatggag aatgagtaag gatggctaag acattgttat
    40201 aggaaataaa aagataacct gtctgatcta ataagaagct agccaaccat gaattgaatg
    40261 gtacccacaa atactccact atcataaaaa tcaagaaaaa tagaaagagg attttatcaa
    40321 gattgaggta aatctgttta agacccaatt ttttaggttt ttcaggtttc ataggcactc
    40381 ctagtcaaat aattgagaca agtccaagcc accaaaagga ttgtttgata agctactttc
    40441 tgtctctaac aattccctag cttgatccga ctctaagaag gattcgtaaa cacgcgccgt
    40501 catccgagca tcctctaaac tattatgaga ctgaccttga aatccaagaa atgaggcaac
    40561 agtttgcaat ttgagattgg caataccatg taaatctgaa ctccgacgtt caaaagcttc
    40621 atcatacaaa tccaccttgt actgttggct atagtctaaa ccatgctctg ctaaaatagg
    40681 taaatcactt ttagcagcat tgtagcctat catcagcaaa gaacccacaa actcttggaa
    40741 ttcttttata actttctcca ctggtggagc atcttttaag gtctcagccg taatccctgt
    40801 caaaccattg ataaaacttt ttagaggtac attggtatga acataggaat cataggcatc
    40861 gatttcccga ccatctctaa aacgcactgc cgatacttga atcaagtgtg tttgtccttc
    40921 gtgctgatta aattctaagt caaaagcaat gtaatcttct aatcgttcca ttctgtacct
    40981 ctcctctact gtctctgttc taatcaacta tactattcac aaacaaaaga agccatcagg
    41041 ttagcattta acctaaacag ctccttgatt atcctccaaa taaacgagca aaaaagcctt
    41101 tcttagtgga ttggacttct tcttttgctt ggtccagctc tagcttaaga ttttcttgat
    41161 ccttcatggc ttgaagggtc aattgttgtt gctgatctaa ttgtttgtct ttctcagcaa
    41221 tctgacggtc tttgatacgc atctgctcgt ctttttctga taactgacga tccttggctt
    41281 ttaattgttc ataaagacga agaatttctg cattcttctc atccactaga atctccatca
    41341 gttcacgttg tttgacatct tcactgacag gttcatcttc aaaaatcgtt tttttataga
    41401 tttcttctag cttaatcaag ccacttctgg taacaactgt tacccctttg tcatttttat
    41461 ctgtgtcttc ttctggtaat tctttgacac ggttattgat tgcttggcga gataatccta
    41521 agacctctgc aatctcactg acggtcattt caatactcat aatatcctct gaaacgtttt
    41581 ctagcttttc tttacttaaa tcttatcata agctagaaaa actgtcaaat ttccgcttaa
    41641 tctaaagtct tcaaaaaggt caacaagact tgggcagagc gacgtccagc ttcgataata
    41701 aactcatcaa aaaagatgtt tgcttcatgg ttggcattgt cactcatagc tctgatgact
    41761 aagactggga gattgagggc atgcgctgct tgagcaatag ctgccccctc catctccacg
    41821 gctaaaactt ctgggaaatg ggacttaatc gcttctatct tgtcatttcc tgcaacaaaa
    41881 ctatctcctg taacaatcaa accaagatgc cagttttggt ccaattgaga taaactctct
    41941 tggatttgag caacaaaggt tttgtctgat tcgaaataaa gcggttgttg cgccatttgc
    42001 ccataagcat agccaaaagc tgtgacatcc acgtcatgat aggctaattt gtcagcaatc
    42061 acgacatccc caacagcgat accttctgct actgccccag ctgaacccgt attaataagg
    42121 gcatccacct ggaaatgatc agccaaaatc gccacactca tagcagacat gaccttacca
    42181 attccacttt ctacaagaac gacttcatga gaagcaatgg ttcctgtatg ataggtattc
    42241 cccaaaacaa cttgctcctg ggtattatct aaatgctgga ccagataagc cagttcttct
    42301 ggcatagcag caataattcc tattttcatt tcaattcctt ttctattaca aaagtttcat
    42361 tgctaaaaca agcaaaatca agagaaagat gaccgcaaat aagattttat tcaacttaga
    42421 attgaagaca tttctcttgg tattttcaat acgacggctt ttatgaatag atggttcgac
    42481 ctgaatcttc aaggtttcct ggctaaaacc atgatcctta ggattggcat aaccaaaacg
    42541 ggaagaagag gttggtaaaa tcttagtttc ctcattatca tctagcaaag gaggacctga
    42601 aattttttcg cctctattag ctctttcaat catttcatcc gttaataaag atttacccat
    42661 actgacctcc tctatttttt ctgcaactcc caatactgaa cagccataat tgtcttggca
    42721 tcacagatat gacctgattg gattaattct ttcgcttctt ctaagctcac ttcaaggact
    42781 tccaaggttt catcctcatc ctgcggacgc ggattttcca cttttgtcaa atcgcttgct
    42841 aaatatagtt ttaacttctc attacaaaag ccaatagctg aataaaaatc gtacaagagt
    42901 tctaatttcc ctgtataggc tgtttcttcc tctaattcac gaagggcagc tgccacaggg
    42961 gctgtgtttt ctcctacctc caattttccg gctggaattt cgtaagagac agcctcgata
    43021 gctttgcggt actgcttgac caagataagt ttttgttcat ccgttactgc taaaacacag
    43081 acagccccat tgtggaaaat caaatcccgt tgggcagttc ccttgccttc tggtaattca
    43141 acctgatctt ggaccagttt aaatattggt ccttgataga tttcttttcg gctaagcgtt
    43201 ttttcttcaa actccatgat aggttcctac tggttcttag gatgatgagg aagacgtgtt
    43261 gcatattcgt ctttattgat ctgacgaccg cgaccaatag caatagcatc tgctggcacg
    43321 tctttagtaa tagttgaacc agcaccaacg agggaattgt caccaagttc tactggtgca
    43381 ataatggttg aatttgaacc aacaaagaca ttgtctccaa tgactgtctt gtatttgttt
    43441 ttgccatcat agttgactgt aatagttcca gcaccgaaat taacgttgct tcccacttca
    43501 cagtttccga tataagtcaa atgaccagcc ttggtattct caccgattga agatcctttc
    43561 acctcaacaa agttaccaat atgaacttgg gcacccagac ttgaatttgg acgaatgtga
    43621 gcataaggac cgactgtcac accgtctgca acactacttt cctcaatcat agaattggta
    43681 atgaccgctc ctgctccgat agtgctgtcc actacataag taccgtttgt caaaacagtc
    43741 tcagcaccaa ttttcgtttg ccctttcaag gtaacattgg cttcgatttg aacttccgga
    43801 gcaatctcaa catcaatatc gatataagtt gcttctggat tgacaaagct aacaccgttg
    43861 accatgtgtt tatgattgat gcgacgacgc ataactgact cagctgtcgc aagcgccaca
    43921 cggtcattta ccccaagact ttcatcaaaa tctttcaaag tataagcgcc aactttttca
    43981 ccagtttcac ggaaaatacc aatgacgtct gtaatatagt attcgccttg agcgttattg
    44041 gtattgatat ttttcaaagc ctcaaacaaa cgctcgttgt caaagacgta tgttccagtg
    44101 ttgatttcct tgatttgctt ttcaaaatct gtagcatcct tctgctcaac aatacgaaga
    44161 acctcagcat tgtcattacg aacaattcgt ccatagccaa aaggattatc cgtttcagca
    44221 gtcaagatag tggccacatt tttatgattg atatggaaat caatcaagtt tttcaagctt
    44281 tcaccagtga ttaaaggagt atctcctgca atgaccaagg tgtgtcctga caaaccttct
    44341 aagataggtt ctgtcatcat aactgcatga ccagttccca gctgttcaga ttgagtcaca
    44401 aattctgtct gtccagccaa gacctcctca accaattctg ccttgtgtcc tacaactgtt
    44461 actgtctttt caggttggat agctcccaca ctacggaaaa catgttccaa catagaaata
    44521 ctcgcaacct tgtgcaaaac ttttggcaaa tcagatttca tgcgagtccc tttacccgct
    44581 gctaaaataa tggcaaaatt tgacataatt ttctcttttc tgtagaaatt cccttttatt
    44641 ataccatatt tcaaatcatt ccgcactctt gaatgaaaaa atgctctaaa gtctcttcct
    44701 taacccattt ttttgatttt ttttgatttt tagggtagaa ttataagata tgagaaaaca
    44761 aattcatcca cttattttat ttagtttttt ggggattatg atgttcattt taatcatcaa
    44821 tcgcccactt aatgacaacc aatcgtttaa aacaaaatcc aatatagcac agattgaagc
    44881 acaggctttg aaacacttag acaaaccgat tattgacctc tctggctggc agcgtcctga
    44941 ggaaatcaac tacgatgccc tctcacaaaa tatttcaggt gctattgttc gtgttcacag
    45001 tggtgctcaa acgacaaaag aaaatgatgc ttcatttatc aatggaatag acaaggccta
    45061 taagagtcat atcactgaac ttcaaaagcg gaatgtccca gttgctgtct acgcttatgt
    45121 agctggaaaa agtgtccaag aaatggaaaa ggctgccgaa gttttctaca atgctgcctc
    45181 tccttacagc cctagttact attggcttga cgtggaagac aaaaccatgt ctaatatgaa
    45241 cgaaggtgtc gaaaattttc gagcaaaact agcatcacta ggtgctaaaa acatcggcat
    45301 ctacgttggt gtctacttca tggaagaaca cagtattgat acaggcaagt ttacctctgt
    45361 ttggattccg tcctacggct cagactcagg attttttgag agcagtccta aaactgattt
    45421 agattatgat attcaccaat acacatctaa aggaaaaatt gccggctttg accacgattt
    45481 agatatcaac gttatctctc ccttaaaaaa taaagaagaa acctttcgaa aactcttttt
    45541 aaaaccttaa aagcatttgt ttatcatttg ctttttcttt ttgtgtctga ttgtgataca
    45601 atatagtaag gattttttga aatagaaata gttggaggaa atatatgctc tcatggttag
    45661 cacgcgttat taaagggatt gtaattgctc ttggatttat cctaccggga atttccggag
    45721 gagttctagc agcaatctta ggaatctatg aacgaatgat tggctttctg gcccatccct
    45781 ttaaagacct taaagaaaat gttttgtact ttattccagt tgccatcggt atgcttctgg
    45841 gaatcggctt attttcctac ccgattgaat acctgcttga aaattatcag gtctttgtat
    45901 tatggagctt tgcgggagct attatcggta cagttcctag cctcctcaaa gaatcaactc
    45961 gagaatctga ccgagacaag attgatttag cttggttatg gacaaccttt atcatttctg
    46021 gattaggact ctatgcctta aattttgtcg ttggaacctt aagcgccagc tttcttaact
    46081 tcgtcctagc aggtgcacta ttggcccttg gcgtcttggt tcctggcctc agcccatcga
    46141 atttactttt gattttggga ctctatgctc ctatgttgac tggttttaaa acttttgatc
    46201 tcttgggaac cttctttccg attggaattg gtgcaggtgc aactctcatc gttttttcaa
    46261 aattgatgga ttatgcctta aacaactacc actcacgcgt ctatcatttc atcatcggta
    46321 tcgtcctatc aagtaccctt ttgatcttaa ttccaaatgc aggaaacgct gaaagtatcc
    46381 aatacacagg actttcactt gtcggttatg tcatcatcgc cttcttcttt gcgctgggaa
    46441 tctggcttgg tatttggatg agtcaattgg aggataaata taaataatgg caaaaaaagt
    46501 taaaatcaaa aaaacattgg tggaacaaat cctatctaaa gcagctatcc ctcatcaggg
    46561 gattcaaatc aatgccctag aaggagagct tcctcaaggt tatgaacgag atcagatttt
    46621 caaaaccttg gcgcttttgg gaaacaagac cggaccgatt atcggaattg tccctatcac
    46681 tcagcacttg tctgaaaaga aactagctaa aatttctggc aataaaaaag tgagcatgat
    46741 tccacaaaag gacttagaaa aaacaactgg ttacattcat ggagccaata atcctgtcgg
    46801 aattcgtcag aaacacaatt atcacatttt tatcgataaa attgctctag atttggatcg
    46861 aatgattgtc tctgcaggcg aagtcggaca cagcattatc gtcgcgccac aagacttggc
    46921 tagctttgta aaggcagact ttgtagatat tttggaggac atcaagtaat gaaactctac
    46981 tttgtccgcc acggtcgtac cctctggaac caagaaggtc gttttcaagg tgctagcggt
    47041 gattctcctc ttcttcctga atccattgaa accctaaaac gacttggcca gtatctcaag
    47101 gaaattcctt ttgatcagat ttattcaagt gatttacctc gagcggtcaa atctgctgag
    47161 attatccaaa gtcaactcca taccccctgt tctttagaaa tcgttcctaa tctccgtgaa
    47221 tggcaacttg ggaagttaga aggtttgaaa attgcaaccc tggaagctat ttacccgcaa
    47281 caaatccagg cttttcgttc aaatcttgct caatttgaca ctcgaatgtt cggagccgaa
    47341 tccctctata gtacaactca gcggaccatc caatttatca aatcattaaa agatagtcca
    47401 gctgagcgta ttctaattgt cggacacggc gccaatctta ctgccagtct tcgtactctc
    47461 ctaggctata aagaaccact tcttcgtaaa gatggcggtc tagcaaatgc cagcctgacc
    47521 attatagaaa cccatgattt tgaaacattc actctcaata cttggaatga tacttcttat
    47581 caatcataat tatagcctag ccttctgaac tagaaccata ggagatatag tcagttgaaa
    47641 caaaaataag acaaaagaac cttgtaaaaa ggtattgcaa cttgccaata cctttttgat
    47701 atgaacacgt gtcttctcaa caggattgta gagcaaaatg aaataagaac tgaataatat
    47761 gatttgagaa tttaaatcaa tttataagaa tgttttagaa gcagttatgt actatttcag
    47821 attcactttt ctatactaag atgagtaggg aggaaaaggt aaaagtttat gcccaaactc
    47881 ttcacataag aactctagct tacccattct atggaatctt gcattatcca ttaaaacttc
    47941 caaactcata ctcttctaaa atctattcaa accacgtcag cttcacatta tatatgttgg
    48001 ttacctcaca agttttatct gcaacctcaa agctgttctt tgaacagcct acagctagct
    48061 tcctagttta atctttgctt ttcactgagt atcaagttaa aaaaatgagg ctggtcaaaa
    48121 agtctttaaa ataaaaaacg catattatca ggtgttaaat gaactgcacc ccaaaagtta
    48181 gacagaaaaa atctaacttt tggagtgttt ttattatgaa attaacttat gatgataaag
    48241 ttcagatcta tgaacttaga aaacaaggat atagcttaga gaagctttca aataaatttg
    48301 agataaacaa ttctaatatt aggtacatga ttaaattgat tgatcgttaa tgttggaaca
    48361 ggcattca
//
LOCUS       DAVDZK010000014        42479 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVDZK010000014 DAVDZK010000000
VERSION     DAVDZK010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42479
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.014"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            1..247
                     /locus_tag="VUX16_000900"
                     /pseudo
     CDS             1..247
                     /locus_tag="VUX16_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1120..1299
                     /locus_tag="VUX16_000901"
     CDS             1120..1299
                     /locus_tag="VUX16_000901"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET8123888.1"
                     /translation="MKTVTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVRE
                     YITDSISTNTIEEAR"
     gene            1910..2194
                     /locus_tag="VUX16_000902"
     CDS             1910..2194
                     /locus_tag="VUX16_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123889.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVKKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            2187..2435
                     /locus_tag="VUX16_000903"
     CDS             2187..2435
                     /locus_tag="VUX16_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123890.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVGGYVLEYHGLPATQDVD
                     AFYDQNQKINEIIARVGKQFNLNTHEELWLNNHVAKQI"
     gene            2531..2749
                     /locus_tag="VUX16_000904"
     CDS             2531..2749
                     /locus_tag="VUX16_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123891.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDAFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(3032..5356)
                     /gene="pflB"
                     /locus_tag="VUX16_000905"
     CDS             complement(3032..5356)
                     /gene="pflB"
                     /locus_tag="VUX16_000905"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET8123892.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGSTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDKYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            5704..6765
                     /gene="dinB"
                     /locus_tag="VUX16_000906"
     CDS             5704..6765
                     /gene="dinB"
                     /locus_tag="VUX16_000906"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET8123893.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIELMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVVLNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(6912..7757)
                     /locus_tag="VUX16_000907"
     CDS             complement(6912..7757)
                     /locus_tag="VUX16_000907"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET8123894.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(7788..7925)
                     /locus_tag="VUX16_000908"
     CDS             complement(7788..7925)
                     /locus_tag="VUX16_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123895.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            8012..8953
                     /locus_tag="VUX16_000909"
     CDS             8012..8953
                     /locus_tag="VUX16_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HET8123896.1"
                     /translation="MLYVGIDVAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALEDTGHYAFNLLNFLHEQGYEVYTYTPLLIKEFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAPRSIGTT
                     SPAREFEIIKHYKRLIDKVEKCVNDLMAEFNSVITTVTGIDNRLGAVILAEIRNIHAF
                     DNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLR"
     gene            complement(9332..11221)
                     /locus_tag="VUX16_000910"
     CDS             complement(9332..11221)
                     /locus_tag="VUX16_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET8123897.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHTKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGAELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVMDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLHLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGIQLKSSFEAVLKEMQEGVRKRVVFWGLPDYYRPLTGGEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVLYYWKLQLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINFYVAYGWHSMFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            11360..12925
                     /locus_tag="VUX16_000911"
     CDS             11360..12925
                     /locus_tag="VUX16_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET8123898.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKVIYS
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMGKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILHFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            12925..13665
                     /locus_tag="VUX16_000912"
     CDS             12925..13665
                     /locus_tag="VUX16_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET8123899.1"
                     /translation="MTQVILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(13774..13989)
                     /locus_tag="VUX16_000913"
     CDS             complement(13774..13989)
                     /locus_tag="VUX16_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123900.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(14860..16110)
                     /gene="ilvA"
                     /locus_tag="VUX16_000914"
     CDS             complement(14860..16110)
                     /gene="ilvA"
                     /locus_tag="VUX16_000914"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET8123901.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGISTYIKETSPEIEIIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHVQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(16160..16300)
                     /locus_tag="VUX16_000915"
                     /pseudo
     CDS             complement(16160..16300)
                     /locus_tag="VUX16_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
     gene            complement(16485..16721)
                     /locus_tag="VUX16_000916"
     CDS             complement(16485..16721)
                     /locus_tag="VUX16_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123902.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMNFEQFFKLAQI
                     SREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(16828..17850)
                     /gene="ilvC"
                     /locus_tag="VUX16_000917"
     CDS             complement(16828..17850)
                     /gene="ilvC"
                     /locus_tag="VUX16_000917"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET8123903.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYIVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGLRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(17916..18392)
                     /gene="ilvN"
                     /locus_tag="VUX16_000918"
     CDS             complement(17916..18392)
                     /gene="ilvN"
                     /locus_tag="VUX16_000918"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET8123904.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(18385..20085)
                     /locus_tag="VUX16_000919"
     CDS             complement(18385..20085)
                     /locus_tag="VUX16_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET8123905.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(20285..21952)
                     /locus_tag="VUX16_000920"
     CDS             complement(20285..21952)
                     /locus_tag="VUX16_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET8123906.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(21955..22320)
                     /locus_tag="VUX16_000921"
     CDS             complement(21955..22320)
                     /locus_tag="VUX16_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET8123907.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(22477..22665)
                     /locus_tag="VUX16_000922"
     CDS             complement(22477..22665)
                     /locus_tag="VUX16_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET8123908.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(22781..22957)
                     /locus_tag="VUX16_000923"
     CDS             complement(22781..22957)
                     /locus_tag="VUX16_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET8123909.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(23068..23265)
                     /locus_tag="VUX16_000924"
     CDS             complement(23068..23265)
                     /locus_tag="VUX16_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET8123910.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(23680..25224)
                     /locus_tag="VUX16_000925"
     CDS             complement(23680..25224)
                     /locus_tag="VUX16_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET8123911.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYDQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            25437..25739
                     /gene="gatC"
                     /locus_tag="VUX16_000926"
     CDS             25437..25739
                     /gene="gatC"
                     /locus_tag="VUX16_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET8123912.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            25739..27205
                     /gene="gatA"
                     /locus_tag="VUX16_000927"
     CDS             25739..27205
                     /gene="gatA"
                     /locus_tag="VUX16_000927"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET8123913.1"
                     /translation="MTFNDKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGFPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            27205..28647
                     /gene="gatB"
                     /locus_tag="VUX16_000928"
     CDS             27205..28647
                     /gene="gatB"
                     /locus_tag="VUX16_000928"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET8123914.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMQTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            28771..29814
                     /locus_tag="VUX16_000929"
     CDS             28771..29814
                     /locus_tag="VUX16_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HET8123915.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTCVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            30145..30705
                     /gene="efp"
                     /locus_tag="VUX16_000930"
     CDS             30145..30705
                     /gene="efp"
                     /locus_tag="VUX16_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET8123916.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            30727..31116
                     /locus_tag="VUX16_000931"
     CDS             30727..31116
                     /locus_tag="VUX16_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET8123917.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            31109..31531
                     /gene="nusB"
                     /locus_tag="VUX16_000932"
     CDS             31109..31531
                     /gene="nusB"
                     /locus_tag="VUX16_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET8123918.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVAEEQ"
     gene            complement(31580..31807)
                     /locus_tag="VUX16_000933"
     CDS             complement(31580..31807)
                     /locus_tag="VUX16_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET8123919.1"
                     /translation="MLSGLIFGLSHLILSHRDPISLLYYSLIGFFFAFVYRSTDNLRL
                     TILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(31829..32220)
                     /locus_tag="VUX16_000934"
                     /pseudo
     CDS             complement(31829..32220)
                     /locus_tag="VUX16_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835936.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(32326..32511)
                     /gene="briC"
                     /locus_tag="VUX16_000935"
     CDS             complement(32326..32511)
                     /gene="briC"
                     /locus_tag="VUX16_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET8123920.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(32670..33437)
                     /locus_tag="VUX16_000936"
     CDS             complement(32670..33437)
                     /locus_tag="VUX16_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET8123921.1"
                     /translation="MNIAKIVREAREQSHLTTLDFATGIFDDFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLRVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGSRAMEAAELMKITSHELLEMDVVDKVISETGLSS
                     KELIKNVKKELQTELARLSQKSLEELLEERYQRFRKY"
     gene            complement(33434..34300)
                     /locus_tag="VUX16_000937"
     CDS             complement(33434..34300)
                     /locus_tag="VUX16_000937"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET8123922.1"
                     /translation="MALFSKKDKYIRINPNRSIREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLVLTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     TMREKTGLDEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEQL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(34337..35704)
                     /gene="accC"
                     /locus_tag="VUX16_000938"
     CDS             complement(34337..35704)
                     /gene="accC"
                     /locus_tag="VUX16_000938"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET8123923.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKTEDLVFAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAESVGYENAGTIEF
                     LLDEASGNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQIRIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(35716..36138)
                     /gene="fabZ"
                     /locus_tag="VUX16_000939"
     CDS             complement(35716..36138)
                     /gene="fabZ"
                     /locus_tag="VUX16_000939"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET8123924.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(36135..36620)
                     /locus_tag="VUX16_000940"
     CDS             complement(36135..36620)
                     /locus_tag="VUX16_000940"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET8123925.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(36623..37858)
                     /gene="fabF"
                     /locus_tag="VUX16_000941"
     CDS             complement(36623..37858)
                     /gene="fabF"
                     /locus_tag="VUX16_000941"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET8123926.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(37880..38611)
                     /gene="fabG"
                     /locus_tag="VUX16_000942"
     CDS             complement(37880..38611)
                     /gene="fabG"
                     /locus_tag="VUX16_000942"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET8123927.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGVISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(38645..39565)
                     /gene="fabD"
                     /locus_tag="VUX16_000943"
     CDS             complement(38645..39565)
                     /gene="fabD"
                     /locus_tag="VUX16_000943"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET8123928.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVSSGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(39558..40532)
                     /gene="fabK"
                     /locus_tag="VUX16_000944"
     CDS             complement(39558..40532)
                     /gene="fabK"
                     /locus_tag="VUX16_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET8123929.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(40651..40875)
                     /locus_tag="VUX16_000945"
     CDS             complement(40651..40875)
                     /locus_tag="VUX16_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET8123930.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(40935..41909)
                     /locus_tag="VUX16_000946"
     CDS             complement(40935..41909)
                     /locus_tag="VUX16_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET8123931.1"
                     /translation="MAFSKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGIIGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(41909..42343)
                     /locus_tag="VUX16_000947"
     CDS             complement(41909..42343)
                     /locus_tag="VUX16_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET8123932.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
BASE COUNT        12795 a         9449 c         7750 g        12485 t
ORIGIN      
        1 ttatcaaggg ctcatgaaga tatatcctca agcacaaact ccacgtaaat ccagcaaact
       61 caagccgcta acagctgaag ataaagccta taaccatgcg ctatctaagg agagaagcaa
      121 ggttgagaac atctttgcca aagtaaaaac gtttaaaatg ttttcaataa cctatcgaaa
      181 tcatcgtaaa cgcttcggat tacggatgaa tttgattgct gatattatca atcatgaact
      241 aggattctgg ttttgcagga agtctaatat gaaaacaaga cgacttccat ataggaaacc
      301 gccttctagc tatgttgagt gatttatatt aaaataactt ttcttctagc ttcattttat
      361 tattataaaa acattcatca taacccccag aacttaaata acgattttta ttcaagatac
      421 atactcctag aataaacttt atatgaaatc cccatttttg tttttacaat tctcctgata
      481 ctcaatgaaa atcaaagagc aaactaggaa gctagctgca ggctgctcaa aacactgttt
      541 tgaggttgta gatagaactg acgaagtcag taacatctat acggtaaggt gaagctgacg
      601 tggtttgaat ttaattttcg aagagtatta gttaaatctt gcttaatata tctacaccat
      661 actattttac atatagtatt tagcacgaca taatactgaa gtctctctcc aaaaaacggt
      721 tatgcctctt tgaataggaa gttctcacaa gaaaagcatc tccacgtttc aacttcatat
      781 ggctcaaaaa caatcaattg atgctaaaac ctgtacctag atgtttcggt tcataaaacc
      841 atgaaactgt aaaaatggat gaaattgata gcgggtagtc agatcaagag acatcataac
      901 tctaaaaagt cacaatatag tagattgaag ttgaaatagt acactttggt ttctaaaaca
      961 ttattataag ttagtttaaa ttccttaatc aatttgtaca tttttatttc atttcactat
     1021 agataagttc atcctcagaa aaatatcatt ctaattgttg aaatggatat ataaacaggg
     1081 gtattaacat taaatgctca tgaaacaacg aatacaggta tcaaaactgt aacaaaacaa
     1141 gtccctaaat ttactaaaga cactgctcaa ctttacacct gtaaatggtt gttgtataat
     1201 aaagttacaa agatgtacga ccacaccgtt gtaaatcata gtgttcgcga atatattact
     1261 gatagcattt ctacaaatac aattgaagag gctagatagg gtttaaacga aatatgtcag
     1321 tgttttagca ttcctagcct tcatatcatt taaagaattg tatagacaaa atttttccca
     1381 atacagacac tcgtaacaac tgcttcattt ttctaccaac atatttagga acaggataag
     1441 atacaagaga attaatccat agatcagttc tataccaatc taagataaat aagctaaaaa
     1501 acaattaata ataagcaaat agattccaaa ttttctctat ctgctcattt taataaacaa
     1561 tactagtgta actatccttc cagtcagaag cttgtcaaac cacatcgaaa atttttctaa
     1621 aatttatctc gttaggcaat caagcaaaaa ctcgacgata gtacaaacat tatcatacag
     1681 gattgacttc ctaaattata tgctttagta aggttttcgg ataagaaaaa aggttcattt
     1741 tacatctcta aacactcttt tctaagatga aaaacagaat ttttcgattg tgatttaaag
     1801 caacaagaag attttcagta tcatcctata gatacgagct aattaagaaa aactacattt
     1861 ttgaatataa actacaataa gataaactaa atttcatagg aggaagacaa tggattggta
     1921 cgattatatg atacaggcat ccaaacaatc acaattcaac gcaagccatt ggtttcgcta
     1981 tttgcgaaaa gttatttttg aagactattc ttatttaaca aaccaagatg taaaaaagtt
     2041 gctagactcc aaagaactaa cccgttttca aaaaattagc ttgaagtatg cctttcaaga
     2101 gcatactcca actcataaat atgtgatttc attaaataaa cctgctaagt taaccaatgt
     2161 tcaaaaattg atggagaaat acaaacatgg ataaaatgaa accggtcttc caagccctaa
     2221 ataaggaatt aattcaggaa aatctgactt taacaattat ctgtgtcggt ggttatgtct
     2281 tagaatatca tggtttacct gccacacaag atgttgatgc tttttatgac caaaatcaga
     2341 aaataaatga aattattgct cgtgtaggaa aacagtttaa tcttaacacc cacgaagagt
     2401 tatggctcaa caatcatgtt gcaaagcaaa tatgaacaaa caacctccct taagtttatg
     2461 cgaatccttg tagtcatttg agaatctgac cgttttagta gtccctattg agtatgtgtt
     2521 aggaatgaag atgatgagta tcagagagca ggatttgcaa gatattggtg caattattaa
     2581 atacaaaaac tttcattcac cattcgatgc ctttaaatat ttaaaagaca tgggatttga
     2641 tactattgac ctctctgttc tattagaagg ttttagttat gcttatggta tggattggtt
     2701 agaaaaattt tttaaagaaa atcaagataa acttcgcgaa ttttattaac agtatcaaac
     2761 aagatgattg tcaattagac agtcgtcttg tttttatgat gaaatgaaat aagaatagga
     2821 caaatcgatc aggacagtca aatcgatttc taagaatgtt ttagaagtaa aggtgtacta
     2881 ttctagtttc aatctattat atttcagatt cggtccacta ttccttccca aaaacattgc
     2941 atattgcgcc gaaggaattg ctcacactat cccaagcaca aacccctcag tcgattgacc
     3001 gagggttcct ttttattatt caagaacttg attagctcaa tgcatccaag gcatcatcca
     3061 ttgaaagaac ttcgtggaag acacgttgtg tcaattcagt tttttgttct ggagtgaggt
     3121 atttagtgtt tacacagtat ccagagatac gtacgataac gtcttcgcct gacatgatct
     3181 tttcgtaaac atcgttcaag tccataacgt tcaagttaac gtgttgtcca ccgttttcaa
     3241 agtaaccatc aaggattgtt accaagttat caacttgttc atcacgagtc ttaccaagag
     3301 cgcgaggtga tacttgtgta gtcaatgaga taccgtcagc tgcataacta aagtcaaggc
     3361 tagaaagtga gttcaagttt tgcaaccaac cacctttagc tttgttagat gggttagcac
     3421 ctggtgagaa gaattcaagt ttagacaagt tcacagaacc atcttcgttg aggtatacac
     3481 ctttgtgaac tggtgagtta ccagtttgtt tagagtaagc aacgttagat gtgattgtca
     3541 aaagtgatac tgtagcttct gcgtctttgt atagtttgtg gctacgtaga cgagttgtgt
     3601 aagcttcgat caaccattct gccaattcgt ttgaacgtgg gtcatcttca ccccagcgtg
     3661 ggtagtcacc gattgtttcg taatcgtaga tgtagccatc ttcatcacgg attggtttaa
     3721 ctgtagcgta tttaatcgct gacaatgtat caacagtgtt agcaaatcca caaataccga
     3781 atcccatgtt ggcacgttgt ttagttggca agaaggccat ttgaacagct tcgtagttat
     3841 acttatcagt catgtagtgg atgatgttca aggcatctac gtaagtgtca gtcaaccagt
     3901 caagagattt ttcaaagttc gctttaactg attcaaattc aagaacttcg tcacgaatag
     3961 gatcgatgtc aaatactttg tagtctttgt gaacatcgtc gtaaccacca ttcaaaccag
     4021 taagaagggc tttgagaacg tttacacgag caccgaagta ctggatgttg tggcgttgtt
     4081 cttcattttc tggatcaagt ggagacacac agcatgagat acagctcatt tcaccatatc
     4141 cgtctttagc cattgttgtt acaccttcgt attggataga agagtgtttg tggctcatgt
     4201 gcatacagta gcgacggaag ttgtatggca atttgtcagt ccaaagaact gtcaagtttg
     4261 gctctggaga gttaccgatg ttgtcaagag tgttcaagaa acggtagtcc atcttagtaa
     4321 cacggtgacg accgtcgtta cccataccag ccatagaagt tgtgatgaat gttgggtcac
     4381 ctgagtacaa ttggtcataa gcttttgtac gagcaaattt aactgtacga agtttcataa
     4441 cgaaatcatc aacgaattct tggatttctg attcagtaaa tgtaccacga gcaaggtcac
     4501 gttctgcaaa gatgtccaat acgattggta cacgacctag agatgtagca gcaccgttaa
     4561 tcacacggca gacagccatg aaagcaatgt taacccattg gattgcttct ttcacgttca
     4621 tcgctggttt gcgaacatca accccgtaaa ggtcacccag gcgaacaact tgttgcaatg
     4681 cttggtattg aaggtttact tcttcacgaa gacggattgt ttcttcatcg atttctttga
     4741 ttgcattcca gtcatttact ttttcttgca tcaagtagtc tgcaccgtaa agagcaagac
     4801 gtgcgtaaac accgatgata cgtccgcgtg agtatgcatc tggaagacca gttacagtgt
     4861 gtgcgtgacg agcgcgacga atatttgaag tgtaggcacg gaaaataccg tcgttaactg
     4921 ttgttacata tttagtgaag atttcgtgaa cagctgggtc tggttcgtat ccattttctt
     4981 ttaaagtagt ttcagccata cggataccac cttttggcat gaagttcaat ttgaagagtt
     5041 catcgttttg gataccgaag ataacttcat tttctttgtc gataaatcca gcagggatat
     5101 cagcgataga tgttggacga gtgtccattg ggaaacgagt ttcttcgtag tgtgctttag
     5161 tttcttctac aattttcttg atgtgaagtg aacgctctgt tgatcctgca aggaagcttt
     5221 cgtctccatc ataaggtgtg tagttagctt gtacaaagcg tgatacactt gctttttctt
     5281 tccaatctac gcctttgaag ccttcccaag ctttgtcaaa aatatcttgt gcttcaacaa
     5341 ctgtcttaac aaccatatta atgtcctctt ttttctagta acagtcatct gttacattca
     5401 tgagacaagt ataccatata gtaaccgttt tcaacaagtg aaaaatccct atttttacac
     5461 tttcttttct aaaacagtct atattttatt tcaaactgta ttatattttt gaaaaaataa
     5521 agtccttttt tctttttttc agaaaaaagg gtataataaa agaaaataag cagtaacact
     5581 caatggaaat cgaaaagcaa actaggaagc tagccgcaga ttgctcaaaa cactgttttg
     5641 aggttgcaga tagagctgac gtggtttgaa gagattttcg aagagtataa aaaggtgcta
     5701 ggcatgttga tttttccttt gttaaatgat ttgtcaagaa aaatcatcca tattgacatg
     5761 gatgcctttt ttgctgcagt ggaaatcagg gataatccta aactcagagg aaaacctgtc
     5821 attattggaa gcgaccctcg gcaaacaggt ggacggggag tcgtttctac ctgtagttat
     5881 gaggcaagag cttttggtgt ccattctgcc atgagttcca aggaagctta tgaacgttgt
     5941 ccccaggctg tctttatctc agggaattat gagaaataca agtctgtggg actccagatt
     6001 cgagctattt ttaagcgcta tacagatttg attgaactca tgagcattga cgaagcctat
     6061 ttggatgtga cagaaaataa actcggtatc aagtcagcgg tcaaaattgc tcgcctcatt
     6121 caaaaagata tctggcaaga actccatcta actgcttccg caggcgtttc ttacaacaaa
     6181 ttcttagcta aaatggcgag tgattatcaa aagccacatg gtttgacagt gattctacct
     6241 gaacaggctg aggattttct caaacaaatg gatatttcca aatttcatgg agtaggaaaa
     6301 aagacagtag aacgtcttca tcaaatgggc gtttttactg gtgctgattt acttgaagtt
     6361 cctgaggtaa ccctaataga ccgttttggt agactaggct atgatctgta tcgaaaggct
     6421 cgtggcattc acaactctcc agtcaaatcc aatcgcatcc gtaaatcaat cggcaaggag
     6481 aaaacctacg ggaagattct ccgtgccgag gaagatatca aaaaagagct gactcttcta
     6541 tcagaaaaag tcgttctcaa tctacatcaa caagaaaaag ctggaaaaat tgtcattttg
     6601 aaaatccgct acgaggactt ttcaactctt accaaacgaa aaagtcttgc tcaaaaaaca
     6661 caagatgcta gtcagataag ccaaatagcc ctgcaactct atgaagaatt aagtgagaaa
     6721 gaaagaggtg tccgcctatt ggggattacc atgactggat tttaaagctc aatgaaaatc
     6781 aaagagcaaa ctaggaagct agccgcaggc tgctcaaaac actgttttga ggttgcagat
     6841 aaagctgacg cggtttgaag agattttcta agagtataaa accttgaaga gttgcccctt
     6901 caaggttttt cttatacaaa taaacggaca aaactgtaaa gtagcaaaac actaccaagc
     6961 acgatacggt atttaccaaa aagggtgaag tcgtgttttt tcacatagct ggtcaagaag
     7021 cgaatagcca ccatgctgac cgcaaaagct actcccatcg cgaccaagag caaaaacaat
     7081 tgcccaaagc tcaagagttc tccggctttc acaaatttga aaatctttaa ggcactagct
     7141 ccaaacataa caggaatccc aagatagaag gtaaattctg tcacaactga acgactggtt
     7201 ccatttaaca aaccaccgac aatcgttgca cctgaacggc tagtccctgg taaaagagca
     7261 agaacttgga agagtccgat atagaaagcg gtcgtataag gaagcttgtc caactctgtt
     7321 acacttggct cgatagcacg cgctttattg cgcttttcca aatagatgaa ggcaaccccg
     7381 tagataatca acatgagagc aactgaaacc atgttatgga agtgggtatc aaaccaatca
     7441 tcaaatttaa agacaccaag taaaggtaaa gtagcaatca agaccttcaa ccatagtctc
     7501 caagtcttac gaacttcctg tttgtcctta gtcggtttaa aaggattgag cttgttaaaa
     7561 taaatcacca taactgctaa gatagcacca agctgaatca cgacattaaa catggacata
     7621 aaggcttcat tttgattttg gtattggata aactcctctg ctaaaatcaa gtgacctgta
     7681 ctggaaatcg gcaaccattc cgtaattcct tcaacaatcc cgaagaagat agattttaaa
     7741 atttcaataa gatacataga ttactcccta tattatattt agcgcagtta gctactgcca
     7801 aagcccaagt ggtatacttg gaataagcca ctgtggatta gttcatttcc tccaatcgct
     7861 tgacgatttc cgaaaggctc taaccacagc ttttgtttca attggtaatg agtttgataa
     7921 cgcatagacg ttttatctcg tctaaggtaa caaggcaaaa agttcgtgga taaccaagta
     7981 gacttgaaat actatatctg gaggtactcc catgctttat gtgggcattg atgtcgctaa
     8041 aaataaacac gatgttacag ccttgaatgt tccaggaaaa actgttctta aaccactcac
     8101 tttttcaaat aataaagctg gttttgaact cttagatctg tctcttcgac agctcaacca
     8161 agactgtctc atcgctcttg aagatactgg acattatgcc tttaatctac tgaacttcct
     8221 gcatgaacaa ggatatgaag tttacaccta cactcctttg ctcatcaagg aatttgccaa
     8281 atcattatca cttcgcaaga ctaaaacgga taagaaagac gctcatggca tcgctcttaa
     8341 acttctttct gaccccaatc gtgaacaatt tcaacacgat aatcggcaag tagaactaaa
     8401 aatactggct agacatattc atcgtctcaa gaaaaaacag tctgattgga aagtacaata
     8461 cactcgttgt cttgatatca tctttcctga gttggataaa atcgttggaa agcattcaga
     8521 atatacctac caactcttga cacgctaccc taatcctcag aaaaggattg aggcaggatt
     8581 tgataagctg atagaaatta agcgattgac cgcttctaaa attcaggata tcctctcagt
     8641 cgcacctcgt tctatcggaa caacatctcc tgctcgtgaa ttcgaaatca tcaaacatta
     8701 caagaggctc attgacaagg tggaaaaatg tgtcaatgac ttgatggctg agttcaactc
     8761 ggtcatcacg acggtcactg ggattgataa tcgtttaggg gcggtcattt tagccgagat
     8821 tcgaaatatt catgcctttg ataatcctgc tcaattacaa gctttcgctg gactggattc
     8881 ttctatttat cagtcaggtc agattgattt agctggaaga atgatcaaac ggggttcccc
     8941 tcatctgcgg taggcactca tacaagctgc caaagcatgc gctcgctttt cacctgcttt
     9001 taaggcctat cttaagacta agttagaata aggaaaacat tacaatgtag ccatcatcca
     9061 ccttgcaaaa aaacttatcc gaaccctgtt ttatatccta aaaaagagct gccatttgac
     9121 gaacaaaaag tgatgtaatt tctgaaatta acacaggatt acctttgaaa aaatggactt
     9181 tttcaagggc tttttgccgt gctctaaaat catcgccaaa tcatcaaatt gaaataagaa
     9241 atagtttaga taaaactatt gacttttctt atagtttgtc ttttttctat cttccattat
     9301 atcatacttt ttcagtctat ggtagctctc tttaaaaggc accgatactg ccgccacctc
     9361 cgcctccaga gaagccacca ccagaacttc cacttccaga agatacagag taggtgcttg
     9421 ctgtatttgc gacactagca taatgactca tttgtgctgt tgaatgataa aacatactgt
     9481 gccagccata agctacatag aaattgatat ctggattttc cacttgaatc tgatgaacct
     9541 tcatcaaatg actaaccttg tccgcatagc caaataaggt cgcatagacc aagaggcgat
     9601 tccagaccac aatactttcc agttcagcct gatccaatcg tgcaatctca cgcaacatat
     9661 tttcaaaact ggtccagaga tagtagacct cagctcccgc ttcatttaga acaccatcac
     9721 gattatctag ttgaagcttc caataataga gaacagacaa aactaaccct agaaaaccaa
     9781 gtattggcaa ggggaggtaa agatagccat gaacgtctaa actgtacaag aacaaaccaa
     9841 atccgataaa taggggcaag atagtcaaga cacccatacc cacttgcaaa gccttttccc
     9901 caccagttaa aggacgatag taatctggga gtccccagaa gacaactcgc tttctcactc
     9961 cttcttgcat ctcttttaat actgcttcga aagaagattt gagctgaatc cctcttgctt
    10021 gaatccgttt ttcatcagaa actttggctc tacgataaag actatcagat accttgtaat
    10081 ccgcaaacaa attggaaaga gtttcttctt ttttacctga aaaagctaga tgtaggcagt
    10141 ctttctcaaa gcttgacaaa ccatcttctt ttactagcct caaaccaact gcatctcctt
    10201 ctgaaataat agaaacattc ccacggtcca tcacatctag caaggtagct tgaataagtt
    10261 ggtcaaaagt gaatttgcca gcccccttga ctaagggact cacttcctcc aaggaggtcg
    10321 agtagacagc ctctgataaa accataggct ctaattccat tggcggttcg tagagacgat
    10381 gatttttagc atatttgatt gaaggagcgg tttttcttct atagataaaa tagaaacaga
    10441 tgctcaataa caaggagatg gaaaggatcg aagggaagat ccaagtaagt agttgtttac
    10501 tttgctcttt ttctttaaca atcgaatcct ctatcttatt aaactcttct aaacgattcc
    10561 ctttcaagcc ctgatcccta gcgctagcaa aatcagttcg aggccagtag gcatgcaact
    10621 cagctccacg cttagccgga agattgtcta aacgaatagt ataatcaagg ttactctttt
    10681 caaccgttct ctctctaaaa agtttccctg tatggaaaaa gagtttctca gcccccttgt
    10741 ctccccttac atgaaattca aacttttcaa tagactctga actatctgtc agaggttgcc
    10801 aatttaattc agcgatatca tcataaagga aaagtaaatt ttttaagttc cagacgagat
    10861 caacttcaac tatgtcgccc tcctgacctg gattatagac tctcacagta taaccatccg
    10921 cttcttctgt tacttcgcta gtcacatctg ctagttctgc accgtttttc gcggcctgaa
    10981 cctttgtatg agggtcaatg tcaaacccgc taggcatctt gccagcacgt ccaagtccca
    11041 cgatttggcc cttaaagtcc tcctcaaact ggtaaactat cttctgtcta aactctgccg
    11101 tattatctgc atgaatatac aaatcccctt gataagagtt tatcttgaaa tcaatggcaa
    11161 aaacagagag tggaagaagg caaaacaagc ctaacaccag taagaaaaaa gtttttttca
    11221 tcaactaagc ccccttttta tctttcttat cattatagca ttttttcgta agcaaaggct
    11281 tacttatgtt gaaaaattac gcatttttcg ataaaatagg agacagttat tttttaatag
    11341 attagaaata ggagaaatta tgagaaaaat atacttatct attttcacaa gtctcttgct
    11401 gatgctagga cttgtcaatg ttgctcaagc cgatgaatat ttacgcatcg ggatggaagc
    11461 agcatatgct ccctttaact ggacccagga tgatgatagc aacggagctg tcaaaatcga
    11521 tgggaccaat cagtatgcca acggatacga tgttcaaatc gccaagaaaa tcgctaagga
    11581 cttaggtaaa gaacctttgg ttgttaaaac caagtgggaa ggtctagtcc ctgcccttac
    11641 ttctggtaag attgacatga ttatcgcagg tatgagtcca actgcagaac gcaaacaaga
    11701 aattgccttt tcgagcagtt actacactag cgaaccagtt ctactggtca aaaaagattc
    11761 tgcctatgca agtgctaaat ctttggatga ctttaacggt gcaaaaatca cttctcaaca
    11821 aggggtctac ctctacgact tgattgcaca aatcccaggt gctaaaaaag aaacagccat
    11881 gggagacttc gctcaaatgc gccaagctct tgaggctggt gtcattgatg cttatgtttc
    11941 tgaacgtcca gaagcactga ctgctgaagc tgcgaactct aagttcaaga tgattcaagt
    12001 agaacctggt ttcaaaactg gggaagaaga tacagctatc gctatcgggc ttcgtaaaaa
    12061 tgacaatcgt attagccaaa tcaatgccag cattgaaacc atttcaaagg acgaccaagt
    12121 tgccctgatg gatcgtatga tcaaggaaca acctgccgaa gctacaacaa ctgaagagac
    12181 tagcagtagt ttctttagcc aagttgctaa aattctttct gaaaactggc aacaactctt
    12241 gcgtggtgct ggtatcactc ttttaatctc tatcgtcgga accatcacag gtctcattat
    12301 tggacttgct attggtgttt tccgtactgc tcctctctct gaaaacaaag tcatttacag
    12361 cctacaaaaa ctagtcggct ggatcctcaa cgtctacatt gaaattttcc gtggtacgcc
    12421 aatgattgtt caatcgatgg ttatctacta tggaactgcc caagctttcg gtatcaacct
    12481 tgaccgtaca ctagctgcta tcttcatcgt ttcaatcaat accggtgcct acatgactga
    12541 aatcgtccgt ggtggtatcc tggcagttga caagggacaa tttgaagctg cgactgctct
    12601 tggtatgact cataaccaaa ccatgggtaa gattgtccta cctcaggttg tccgcaatat
    12661 cctaccagca actggtaatg aatttgtcat caatatcaaa gatacatctg tattgaacgt
    12721 tatctctgtt gtcgagcttt atttctcagg aaataccgtg gcgacgcaaa cctatcaata
    12781 cttccagaca tttacaatca tcgccgtgat ttactttgtc ctcaccttca ccgtaacacg
    12841 tatcctacac tttatcgagc gcagaatgga catggatacc tatactacag gtgctaacca
    12901 aatgcaaacg gaggatttga aataatgaca caagtaatcc ttgaaattaa acacctcaaa
    12961 aaatcctatg gacaaaacga agtgctaaaa gacatttctc tcactgtcca caagggagaa
    13021 gttatctcta tcatcggaag ctctggaagt gggaaatcga ccttcctacg ctccattaac
    13081 ctacttgaaa cgccaactga tggacaaatc ctttatcatg gacaaaacgt cctcgaaaaa
    13141 ggctatgacc tcacgcaata ccgtgaaaag ttagggatgg ttttccaatc ctttaacctc
    13201 tttgaaaatc tcaacgttct tgaaaacaca atcgtcgctc agacaactgt ccttaaacgc
    13261 gaacgcacag aagctgaaga aattgccaaa gaaaacctgg aaaaggtcgg catgggagaa
    13321 cgctactggc aagccaaacc aaaacaactc tcaggtggtc aaaaacaacg tgtggccatc
    13381 gctcgtgccc tctccatgaa tccggacgct attctctttg atgaaccaac atcagctctc
    13441 gatccagaaa tggttggaga agtcctcaaa atcatgcagg acctggctca ggaaggcttg
    13501 accatgattg tcgtaaccca tgaaatggaa tttgcccgtg atgtctctca ccgtgttatc
    13561 tttatggata agggcgtgat cgctgaagaa ggtaaaccag aagacctctt caccaatcct
    13621 aaagaagacc gaacaaaaga gttccttcaa cgctatctca aataaaaaga aaaggctgca
    13681 tcaaccgtgc agtctttttg ctgtcctcaa aatgaaaagg cagattctct atctctacta
    13741 cttgaaggtc aagaatccgc cgttatccaa agattaatct tcaaattttt cataattttt
    13801 ttcatagaaa tcaattaggc ctagggctgt ttcaaatgaa atatttttta cttttgcacg
    13861 accctgcgcc agagcaatga tagacatttc acgcgcattc gtttctttag agatacggta
    13921 gcctgtgatt ttcttatcac gaacccagcc aacaactgat tctacttttt caaagtttga
    13981 cttagccatg tttttctcct attttcttct ttataatatt taattgtata cgtttttact
    14041 acttttgtca ataaaaaaaa catatattca acgaaaataa ttagttcaga attttcttac
    14101 ttccttttta aacccgataa tatataggtt ttgctagcct ctacaccata aatatttgct
    14161 aataaaaata ctgtattatt accctcttaa ggtgcgaaat tattcaagtt cttaaaaaat
    14221 gcttctctat ttccgtaaga tagcttattt cttcgattta agaactgaag atgatagttc
    14281 taacctttag aaatccaagc cttcactagc tcaaaaactc ctatctttct tcctcaataa
    14341 atcatctgag agataggtat tccttatatc cttcaaattc atcactcctt tggatattga
    14401 ggtgctagcc tagaagcaga cacccgatta tctaaaccat ccttaataga gatgacaaga
    14461 cagataagct cagttaatta cttatatatc tttttaatat ggtatatttg tcaacaaaaa
    14521 gaaatcaaat cataccttat actcaatgaa aatcaaagag caaactagga agctagccgc
    14581 aagttgctca aaacactgtt ttgaggttgc agatagagct aacgtggttt gaagagattt
    14641 tcgaagagta ttaaagacag tgtgactatg cttgtcaata gataggaaat caaaatgaag
    14701 gatggaaatc tgagccaaac atcataaatg ctataatgaa cagaagtaag aattgcacga
    14761 taagcttcct aaaaccatag gaatcgctcc ctttcttcat cttcattata gcacctatac
    14821 atcagttgtg caaataatat gatatttttt tattagtcct cagacaagca tattataaag
    14881 cgtttcatta ccatttaagt taatataagc tggatcaaaa ccttccattc tacggatcaa
    14941 acctgcataa tcatgcttat ctgccaaagc gatcccaatc aatactgggc ctgttccctt
    15001 gctagctcgt ttgatatact caaaacgtgt gatatcgtca tttggaccca gaatatcatt
    15061 tacaaactca cgcaaagcac ctggacgctg tggaaaattg accacaaagt aatgcttgat
    15121 gccatcataa atcaaggcac gctcttccat ttctggcata cggttgatat cattatttcc
    15181 tccagaaatg atacaacaaa tggttttccc cttaatatat tcagccaaaa cctctaaaga
    15241 ggcgatacta gccgctccag caggttctgc gacaatccct tgcttagagt agaggtcaat
    15301 caaagtttca gaaatcagcc cctcatcaac acctactaaa gtttgaacat gttgacgagt
    15361 tgcctcatag gtcaactgac ctaccttttg cacagcaatc ccatccgcaa atttatcaat
    15421 ttccttgagt ttgactggac ctccagcctc aaaggcagct ttcatggaac gcgctccatt
    15481 cgcctctact ccgataatct caatctctgg acttgtttcc ttgatatagg tagaaatccc
    15541 ggcaatgaga ccgccaccac caacaggaac caagacagca tcaaaatcaa tcgattcttt
    15601 tcgagcttct tctaaaatct cataagcaac tgttccttga cctgcttgaa catgagcatc
    15661 atcaaaagga tcaataaagg tacgattctc agagactgta aattcttgag ctgctttggc
    15721 tgaggcatca aaggtatctc caactagttt aatagttaca aaatccccac caaaaaagcg
    15781 aacttgacca attttttgtt gtggcgtagt aatgggcata aagatagtag caggaatttt
    15841 catctcatta caagtatagg caactccctg cgcatgattt cccgcagagg cacagactac
    15901 cccacgctca cgctcttcct tgctgagctg agaaatagca taataggcac cacgaatttt
    15961 aaaagagcga acacgttgag cattttcctt tttcaaataa atcttagcac catacttctc
    16021 cgataaataa tgatcgtaat ccagtggagt attcacaacc acaccgttca agaccttgtg
    16081 agccttgatt atatcttttg aacttaacat ataaaacctc tttttctata aaaaacagtc
    16141 actaatgact gttttttagt tattcatctc cgaaaacttc agtaacactt tcatggtatt
    16201 tatgagccat acgaatcgaa aactctttag gaagttcata acgatttgtg gaaatccaat
    16261 catataacca ttctaccaaa ctttcttcac tatcattacg aaagttttcg cagtccagtc
    16321 atttaaaccc gattctttca atccagatgc aataatttgc tctatttgat ataaaccgcc
    16381 atctatcgtc tcatttattc tgcgaagagg accttcaata taggataaag cttctccgaa
    16441 tctaacagct gatttaggtc ctaatgattt accaactata tttgttaatg ttttttattt
    16501 ctcaaaatcc atttcgctat ataacgagca gatttagtcg caccagctct ctcaaacgga
    16561 gaatgaattt caagaccttc ttctctagat atttgtgcca atttgaagaa ttgttcaaag
    16621 ttcatatgca acctaccatc ttcaaaatta gcatcatcat aaatgttaat tacagcattt
    16681 tcatcatacg accaatctgc tttattttgg tctgctagca ctattaccga cggtgtaatt
    16741 acattataca actagaacca ataataacga tgcaattttt ctcataatct ttttcataaa
    16801 atcatctcca gcgctatata tttctaatta gttatagatt ttgaatgcat catcgtcgtt
    16861 tttaccaacg aatggcattg ctttacgcaa ttctgcacca actttttcaa tttcaaggtt
    16921 agctgcttgt tcacggtaag cagtcaattt tggacgtcca gctttatagt catttacaaa
    16981 gtcatttgca aatttaccat tttggatgtc tgccaagaca gccttcatat tttctttaac
    17041 ttgttcagtg attacacgta gacctgatac atagtcaccg tattcagcag tgtttgaaat
    17101 agattgacgc attttcttga atccaccttc gtagatcaag tcaacgatca atttcatttc
    17161 gtgaagaact tcaaagtaag ccaattctgg agcgtaacct gcttctgtca agacttcgaa
    17221 acctgcttcg ataagggcag tcaaaccacc acaaagtaca gcttgttcac caaacaaatc
    17281 ttcttcagtt tcttctttgt aagttgtttc aagaagacct acacgagccg ctccaacacc
    17341 tttacaccag tccatagcaa tgtttttagc atttcctgtt gcatcttgat atactgcata
    17401 aagagctgga acaccaaatc cttcttcgta agtacgacgt accaagtgtc ctggtccttt
    17461 aggagcacac atgaagacat ctacatccgc aggaactttg ataaattcaa agtggatgtt
    17521 gaaaccatgg gcaaatccaa ctgcgtttcc agcttccaag tttggagcga tttctgcttc
    17581 gtacaattct tgttgaattt cgtctggcgc caagatcatg ataacatcag ccaacttagt
    17641 agcttctgct actatgtaag tatcaaatcc atcttctttt gctttatcaa aagatttacc
    17701 tggacgtaca ccgataataa cgtcacgacc tgaatcacgc aagttttgag catgcgcatg
    17761 cccttgtgaa ccataaccga taacggcgat ttttttaccg tcaagtgctg ctactttaac
    17821 atctttttca tattccattt gaactgtcat agcttttctc tcttttctat tatttattgc
    17881 cttttaggct ggtttaataa atttaagttg gatttttaat cgcgggtaaa tccagttgca
    17941 cccgttcgag caatattgcg aataccgtat gggcgaatga ctcgcaatag ggcttcgctc
    18001 ttttctgcat ttcccgtcat ctgaatggta atcgagcttg gcgctacgtc taccactgtt
    18061 gcacggaaag gttgaataat cgctaaaatc tcagctctct tctcagctgg cgctgacatc
    18121 ttaaccaaaa tcacctcgcg ctccaaatga ggcttgtctg taatatctcg aatgcgaatc
    18181 acatcaatct gacgattgag ctgtttgatg atttgctcca cttcatcatg agaagcaaca
    18241 tcaataataa tagtgatacg cgatacattc ggatcttctg ttgctccaac agagatgctt
    18301 tcaatattaa cctgacgacg agataggaca cctgtaaagc gattgaggac tcctgaacga
    18361 ttttgtagtt ttgctgttaa cattctacgc atggaactgc acccccaaca tctcatgatt
    18421 actcttacca gccggtacca ttggtaacac ctgttcctta cgagaaatat ctacctcaat
    18481 tagcatagga acatcctcag tgatgacttc aaggtcttga gccaaggtct caggattgtc
    18541 aaacttatag tttttaatac cataagcctg cgccatcaat tggaaatcag gaagggtatc
    18601 aaagaccgac tctgatgttc tgccttcata gaaggattcc tgccactggc gaaccattcc
    18661 aagtgaatga ttgttcagca taaccacctt gattggcacc ttgtaaatat tcaaaatagc
    18721 caactcctgg ttggtcattt ggaaaccacc atccccaaca aacaagacta cctccttatc
    18781 tgggttagca attttagcac cgattgctgc tggaattcca aatcccattg ttcccaaacc
    18841 acctgaagtc actaactgac gttcattttg gtagggataa tactgagctg tccacatttg
    18901 gtgttgacca acgtctgtta ccacaatggc atctccattc gtcaattcac caattcgttc
    18961 aataactgct tgcggttgaa ccacacgctc tttcttgtca taagaacgaa cacgattctt
    19021 gtctttagtg actttctcaa tccacttttc agtattgttg tgaactgttg gttctgctag
    19081 caacatttgc aaggccttct tagcatctcc aactacagga atgtctgcac tgataatctt
    19141 gccaatctca gctgggtcaa tatcaatgtg ggcaacctta gcattcttag cgaaagtctt
    19201 aggattcccc gtcaaacggt catcgaaacg agaaccaata ctaatcataa agtccgcttc
    19261 cgtcatggca atatttgctg cgaatgaccc gtgcatgcct cccattccaa gaaagagtgg
    19321 gtgactcgtt gcaatcgttc cttgtcccaa aagactggtt accactggaa tttgatagcg
    19381 ttctgcaaat tcatttagtt ccgtagcagc ctcagcataa ctaattccac caccagctaa
    19441 caagactggc tttttagcct tggacaattg cttcaagatt ttcttgattt gcatatcatt
    19501 cggctcaaga gtcggctgat aacttggtaa attcacttct ggtgaataaa tgaagtctgt
    19561 ttctaaagca gatatgtctt ttggtaggtc aattacaact ggccctggac ggcctgtagt
    19621 tgcgatatgg acagcttccg taatgatacg cggaatatca gctgtctcac gaacttggta
    19681 attgtactta gtgattggca tggtaattcc cacgatgtct gcctcctgaa aggcatcctt
    19741 cccaatccct gctcgcgcca cctgacctgt aaagaccaaa aggggaacgc tatcgctcat
    19801 ggcatccgca atccctgtaa tggcatttgt tgctcctggt ccactagtga cgacggcaac
    19861 acccaacttt ccagttgatt tggcataacc ttcagcttca tgcaaacaac cttgctcatg
    19921 gcgccctaga atgtggcgaa tgcctttaaa attatatatc gcatcataaa aaggcaaaac
    19981 cgcaccacca ggataaccaa agatggtatc aactcctaaa tcacgaagtg tttccaaaac
    20041 taggtccgac cccgtcttag gagattctaa actgattttc tccattattc ccctttcttt
    20101 cctcttaaaa ataacttgtt actatcatac cattttttca aaatttttca agataaaaga
    20161 agaaattttc tgaattttct attttaacgt ttatttatga atgttatttt tgtttttatt
    20221 aaaaagatac cgatttcatt tactaaaaag aaaaaagaac tgatttctca gtccttcatt
    20281 aatcttattc cacactaaat aggtatgggt aaacaggttg ttgaccttgg tgaatctcga
    20341 cttcaacgtc ttcgaattct tctacgattt cttgagcgat ttcattggca agttcttcgc
    20401 ttccgtcttc accgacatag aaggttacga tttcactatc ttcatccaac atatgtttca
    20461 aggtttcagt caatgtttgg tgcatatcag ggtttgacac aagaattttt ccatccacca
    20521 tacctagatt atcgttttca tggatttcta agccatcgat cgttgtatca cgcacggctg
    20581 ttgtgacgct tccgctaacg acatcgctaa gagcagctgt catacgctct tggttttctt
    20641 caatggactt gcttggatca aaggcaagaa gacttgtcat accttgagga agagtgcgag
    20701 cctctaccac tactgctggt tgctccaaaa cttctgccgc agattgagct gccatgaaga
    20761 tgttcttgtt gtttggcaag aagatgatgt tacgggcatt gacctgttca acagccttga
    20821 taaagtcttc tgttgaaggg ttcatggttt gaccgccttc gataacataa tccacgcctt
    20881 gagaacagaa gatatctgct agacctttac cagccaccac agcaatcaaa gcatactctt
    20941 tttcttcagc cgacttgata acttgagtag cttctttctc aacctgtgct tcgtgttggt
    21001 tacgcatatt gtcaactttt accttgacca agctaccata tttgagacct tcttgcataa
    21061 caagtcctgg atcttctgta tgaacatgga ctttgacaat ttcatcatcg ttaacaacga
    21121 ggagagaatc cccaagctca tccaagtagt tacggaattc atcgtagtca aaatctttag
    21181 cataggttgg accttgctta agagctacca tgatttcagt acagtaacca aacgtgatgt
    21241 cctcagttgc tacgtgacca gctacagact tatgatgctc tacattgatc atctcactca
    21301 tgttggcagg agtcgctaca aagtcctcag atgcaatata ttcgccagta agggctgaaa
    21361 ggaaaccttc gtagatgaag accaatcctt gaccacctga gtccacaacg ccaacttctt
    21421 tcaatactgg aagcatgtct ggtgttttag ctagagctgt tttagcacct tccaaggctg
    21481 cgcgcatgac ttcaacagtg tcatctgttt gctcagcttt tttcttagca ccgatagcag
    21541 ctccacgaga aactgtcaaa atcgttcctt caacaggttt catcactgcc ttataggcaa
    21601 cttccacacc tgattggaag gccagagcca agtcttgacc tgttaactcg tctttatcct
    21661 tgatagcttg ggaaaatcca cggaaaagct gagacgtaat cactcctgag ttcccacgcg
    21721 cacccatcaa aagccctttg gcaagaatgc tcgctacttc tccaactgta gaagctggct
    21781 tgtctgcaac ttctttagca ccattttcaa tggtcattcc catatttgtc ccagtatctc
    21841 catctggaac tggaaagacg tttaatgaat tgacatattc agcttgctta ttcaagcgag
    21901 ttgatgcagc ctgcaccatt tcttgaaata agctagtagt aatttttgac acggttattc
    21961 tcctacaact ttgatatttt gaatgtagac atttacagtc tgagcagtaa ttccaagctg
    22021 gttttccaag ctaaaggcaa cacgctcttg aatgtttttt gacacttcac taatctttgt
    22081 tccgtagctt aacacggtat atacatcaac tgcaatactg ccatcttcgg ctgcctttac
    22141 gacgacacct ttagaataat tttccttacc tagcagggct tggaaattat ctttgagggc
    22201 atttttacta gccataccga ccacaccaaa aatctcagtt gctgctccac ctacgacggt
    22261 tgcaatcact tcatctgtta gttcgatttg accatctttt gtattaattt ttacagtcat
    22321 cctttttacc tcaactagtt gatactctat tttatcatat ttcagcccaa gtgtaaaagc
    22381 agaatgatgt atcagcggat atttactcta tttttcaaat gatgttatac ccacaataaa
    22441 agaaaaaaga ccctaaggtc tcctttgctt ttattattaa acgcgttcaa ctttacctga
    22501 tttcaaagca cgagctgaag cccaaacttt tttaggttta ccatcgataa gaacagtaac
    22561 tttttgaagg tttggtttta cggcacgttt tgtttggttc atcgcgtgtg aacggttgtt
    22621 tcctgataca gtcttacgac ctgtaaagta acatacttta gccattgtgt tttcctccta
    22681 ttagatctaa tatagcggat gtgctagcac cacataccgt actatgttat cacactttct
    22741 tgttttttgc aagggaattg gaagattttt tatttgtgtc ttaaatcagg tcttgcgtga
    22801 cattttctgc tctccacatg ccatcgttga ttaacagaac accagaatta aaattatgtg
    22861 tataaaaatc atctctaact gcagctaagg gtatagccgt caagtccaaa tcccacagct
    22921 catctatcga ttttcttaca acaatatctg aatccaaata cagtacacga gactcgctta
    22981 catactttgg aataaaatac ctaaaaaagc cgcatatgaa agtccctcaa aggggagacg
    23041 ataacctttc agaatattac tgtcaatcta aacattcaca atctcactat tcaaagtctc
    23101 tagtcttttt tccatcaatt ggaaccattc tcgcggaagg tcatcattaa aaacataaaa
    23161 cttaagatta taatgatgaa cacaaagaga ttttattgtt gtttcaactt tatccatata
    23221 agcattatct gcacctaaga caatcgcttt tttctcttct ttcacttttt atctcatttc
    23281 tttttattcc catcatatta ttcccatcat atgtttctac gtaaccatta ttttcgccta
    23341 ttcgttcgta aaactatacc agtggagatt ttagatgaag tcccattacg gtttacaatt
    23401 tttacattac gacacggagt tttacaaatc gatttcattt gccaaacgta gttagtaagg
    23461 cagttagcta ggctacctac tttctgctac gacggaaaaa tccacaaatc aataccattc
    23521 gtggattttt cctagtgaag cgtttaggta agccgccata gcggttaccg attattagat
    23581 tacgacacgg agtttggcaa atcgattcta tttgccaaac gtagttagtg actcagtacc
    23641 aacaatttgg aactttagtt ccaaattgtt ggtactgagt cacatcttct cctctaactc
    23701 tacgtctgga tacttgtccg caaaccagcg gagggcaaag tcattttcaa agagaaagac
    23761 tggttggtca aaacggtctt tggctaagat attgcgactt gacgacatcc gttcatccaa
    23821 gtcctcaggc ttgatccaac gaacggtctt tttacccatt gggttcataa ctacttccgc
    23881 attgtactca ccttccatgc ggtgtttaaa gacttcaaac tggagttgac ctacagcgcc
    23941 tagcatgtac tcacctgttt ggtaattctt ataaagctga acggctcctt cttgcaccaa
    24001 ttgctcaatc cccttgtgga aggatttttg cttcataaca ttcttagcag aaactttcat
    24061 gaaaatttca ggagtaaagg ttggcagtgg ttcaaattca aacttgtttt taccaactgt
    24121 caaggtatcc ccaacttgat aagtacctgt atcgtaaacc ccgataatat cacctgccac
    24181 ggcattggtc acattctcac gactttccgc cataaactga gtaacattag acagtttagc
    24241 ccccttacca gtacgaggga gattaacact catgccgcgc tcaaattcgc cagatacgat
    24301 acggacaaag gcaatacggt cacggtgacg agggtccatg ttggcttgga ttttaaagac
    24361 aaagcctgag aaatccttgt cataaggatc cacaatttca ccatctgttt tcttgtgacc
    24421 atgtggttct ggagcaaact tgaggaaggt ttcaaggaag gtctgcacac caaagtttgt
    24481 cagggctgaa ccgaaaaaga caggcgtcaa ttctccagcc agaatagctt cctctgaaaa
    24541 ctcattccca gcttcattta aaagctcaat gtcatccttg acttgatcgt agaaaggatt
    24601 gctaccaaag agtttgtccc cgtcttctag actggcaaaa cgctcatccc ctttgtaaag
    24661 ctctaaacgt tggttataga ggtcatacaa gccctcaaag gctttcccca tcccgatagg
    24721 ccagttcata gggtagctag caatgcccaa gatttcttcc aattcttgca agagatccaa
    24781 aggctcacga ccgtcacgat ccaacttgtt cataaaggta aagactggaa tgccacgatg
    24841 tttcacaacc tcaaacagtt tctttgtttg agcctcgatc cccttggcag agtccacgac
    24901 catgaccgca gcatccaccg ccatcaaggt acgataggta tcttctgaga agtcctcgtg
    24961 ccctggcgtg tctaagatat tcacgcgctt gccgtcgtag tcaaattgca taacagatga
    25021 agtaacagaa atcccacgtt gcttctcgat atccatccag tcagatttag caaaagtccc
    25081 tgttttcttc ccttttaccg taccagcctc acgaatctca cccccaaagt agagtaactg
    25141 ctcagtgatg gttgttttcc ccgcgtccgg gtgggaaata atggcaaagg tacgacgttt
    25201 cttaatttct tcttgaatat tcataagttc tctttctttg attctctatt tttcttgttt
    25261 caatagctga gaatgatttt tacattggat tttaccattc ctttcaacac tccattatat
    25321 cggattttag catttttttc aatttctatt tcttttcact tccccctccc ttatttatag
    25381 gaaaatatgg taaaatagaa cagactaaaa atcatcattt cacgaaagga tgcaagatga
    25441 aaattacgca agaagaggta acacacgttg ccaatctttc aaaattaaga ttctctgaag
    25501 aagaaactgc tgcctttgcg accaccttgt ctaagattgt tgacatggtt gaattgctgg
    25561 gcgaagttga cacaactggt gtcgcaccta ctacgactat ggctgaccgc aagactgtac
    25621 tccgccctga tgtggccgaa gaaggaacag accgtgatcg cttgtttaaa aacgtacctg
    25681 aaaaagacaa ctactatatc aaggtgccag ctatcctaga cgatggagga gatgcctaat
    25741 gacttttaac gataaaacta ttgaagagtt gcacaatctc cttgtctcta aggaaatttc
    25801 tgcaacagaa ttgacccaag caacacttga aaatatcaag tctcgtgagg aagccctcaa
    25861 ttcatttgtc accatcgctg aggagcaagc tcttgttcaa gctaaagcca ttgatgaagc
    25921 tggaattgat gctgacaatg tcctttcagg aattccactt gctgttaagg ataacatctc
    25981 tacagacggt attctcacaa ctgctgcctc aaaaatgctc tacaactatg agccaatctt
    26041 tgatgcgaca gctgttgcca atgcaaaaac caagggcatg attgtcgttg gaaagaccaa
    26101 catggacgaa tttgctatgg gtggttcagg tgaaacttca cactacggag caactaaaaa
    26161 cgcttgggac cacagcaagg ttcctggtgg gtcatcaagt ggttctgccg cagctgtagc
    26221 ctcaggacaa gttcgcttgt cacttggttc tgatactggt ggttccatcc gccaacctgc
    26281 tgccttcaac ggaatcgttg gtctcaaacc aacctacgga acagtttcac gtttcggtct
    26341 cattgccttt ggtagctcat tagaccagat tggacctttt gctcccactg ttaaggaaaa
    26401 tgccctcttg ctcaacgcta ttgccagcga agatgctaaa gactctactt ctgctcctgt
    26461 ccgcatcgcc gactttactt caaaaatcgg ccaagacatc aagggtatga aaatcgcttt
    26521 gcctaaggaa taccttggtg aaggaattaa cccagaggtt aaggaaacca ttctaaatgc
    26581 cgctaaacac tttgaaaaac ttggtgctat tgtcgaagaa gtcagccttc ctcactctaa
    26641 atacggagtt gccgtatact acatcatcgc ttcatcagaa gcttcatcaa acttgcaacg
    26701 ctttgacggt atccgttacg gctatcgcgc agaagatgca accaaccttg atgaaatcta
    26761 tgtaaacagc cgaagccaag gttttggtga agaggtaaaa cgtcgtatca tgctgggtac
    26821 tttcagtctt tcatcaggtt actatgatgc ctactacaaa aaggctggtc aagtccgtac
    26881 cctcatcatt caagatttcg aaaaagtctt cgcggattac gatttgattt tgggtccaac
    26941 tgctccaagt gttgcctatg acttggactc actcaaccat gacccagttg ccatgtactt
    27001 ggctgacctc ttgaccatac ctgtaaactt agcaggtttc cctggaattt cgattcctgc
    27061 tggattctct caaggtctac ctgtcggact ccaattgatt ggtcccaagt actctgagga
    27121 aaccatttac caagctgctg ctgcttttga agcaacaaca gactaccaca aacaacaacc
    27181 cgtgattttt ggaggtgaca actaatgaac tttgaaacag tcatcggact tgaagtccac
    27241 gtagagctca acaccaattc aaaaatcttc tcacctactt ctgcccactt tggaaatgac
    27301 caaaatgcca acactaacgt gattgactgg tctttcccag gagttctacc agttctcaat
    27361 aaaggggttg ttgatgccgg aatcaaggct gctcttgccc tcaacatgga catccacaaa
    27421 aaaatgcact ttgaccgcaa gaactacttc taccctgata atcccaaagc ctaccaaatt
    27481 tctcagtttg atgagccaat cggttataac ggctggattg aagtcgagct agaagacggt
    27541 acgaccaaga aaattggtat cgaacgcgcc cacttagagg aagacgctgg taaaaacacc
    27601 cacggtacag acggctactc ttacgttgac cttaaccgcc aaggggtacc tttgattgag
    27661 attgtatctg aagccgatat gcgttcgcca gaggaggcct atgcttatct gacagccctc
    27721 aaggaagtta tccagtacgc tggcatttct gacgttaaga tggaagaagg ttctatgcgt
    27781 gtggatgcca acatctccct tcgcccttat ggtcaagaaa aattcggtac caagactgaa
    27841 ttgaagaacc tcaactcctt ctcaaacgtt cgtaaaggtc ttgaatacga agtccaacgc
    27901 caggctgaaa ttcttcgctc aggtggtcaa atccgccaag aaacacgccg ttacgatgaa
    27961 gctaacaaaa caaccatcct catgcgtgtc aaggaagggg ctgctgacta ccgctacttc
    28021 ccagaaccag acctacccct ctttgaaatt tctgacgagt ggattgagga aatgcagact
    28081 gagttgccag agtttccaaa agaacgtcgt gcgcgttatg tatctgacct tggtttatca
    28141 gactacgatg ctagtcagtt gactgctaat aaagtcactt ctgacttctt tgaaaaagct
    28201 gttgccctag gtggtgatgc caaacaagtc tctaactggc tccaagggga agtcgctcag
    28261 ttcttgaatg ctgaaggtaa aacactggaa caaatcgaat tgacaccaga aaacttggtt
    28321 gaaatgatta ccatcatcga agacggtact atttcatcta agattgccaa gaaagtcttt
    28381 gtccatctag ctaaaaatgg cggtggcgcg cgtgaatacg tggaaaaagc aggtatggtt
    28441 caaatttcag atccagctat cttgatccca atcatccacc aagtctttgc cgataacgaa
    28501 gctgctgttg ccgacttcaa gtcaggcaaa cgtaacgccg acaaggcctt tacaggattc
    28561 cttatgaagg caaccaaagg ccaagccaac ccacaagttg cccttaaact acttgcacag
    28621 gaattggcga agttgaaaga aaactagaca gaacaaaacc agccctaagg ttggtttttt
    28681 cttgacaaat agaaagaaaa cgtttacaat attgcgtgta aagtttccaa acaagaaaac
    28741 taaaaatcgc aacaataagg agttatttat atggctacaa tgaaggcagc tcgctggcat
    28801 gcagcgaaag atgttcgtat tcaagaaata gaagttcctg aagtacttcc gcaccaagta
    28861 aaagttgcag ttaagttcac aggaatttgt ggtactgacc tccatgaatt tttagatgga
    28921 cctatcttta tcccaacaga tgagcacgtc tattctggtc aaaaagcacc ggtaacactg
    28981 ggacatgaat tttctggtga aatcatagaa gtcggaagcg atgttacctg tgttaaagtt
    29041 ggtgatcgtg ttgctgtgga accaattcta gctaaaaata acttagttgg tgattataat
    29101 ttggatccaa accttaattt tgtcggtttg gctgcagacg gtggatttgc caaatattgt
    29161 gttttagacg gtgacttagt acatgtcatt ccagatagct tgagctatga gcaagctgct
    29221 cttactgaac ccgctgctgt tgcagtctat gctgttcgtc aatcttcttt gaaggctggc
    29281 gatacagctg ttgtctttgg tttaggcccg attggtctat taattgtaga agctcttcgt
    29341 gcagctggtg cttctaagat ttatgctgtt gaactatcac ctgaacgtca agcaaaagct
    29401 gaagagttag gagctatcgt tgtccgtccg gaagaaggtg aaacagctgt tgaagctatt
    29461 catcgtttaa caaacggtgg tgtagatgtt tcttatgaag taacgggtgt gccagtagtt
    29521 ttaggacaag ccttagctgc cgtacataaa gcaggtgagt gcatggtggt ctctatctgg
    29581 gaacgagaag caaatattaa tccgaatgaa tttgcaatcc aagaaaagac actaaaagga
    29641 atcattgctt atcgtcatat cttccctaaa gtattagaat tgatggaaca aggctacttc
    29701 tccgctgaaa aattagttac taagaaaatt aaattggaaa atatcgtcga agaaggcttt
    29761 atcgaattaa ctcaagataa gtcacaaatt aaaattttgg tagaaccaga ataaaaaatc
    29821 aatcttttta agacaatact aacaggtcgg agtaaactta cttcggcctt ttgaaatata
    29881 atactcttcg aaaatctctt cagaccacgt cagcgtcaca ttaccgtact caaatacagc
    29941 ttgcggctag cttcctagtt tgctctttga tttccattga gtatgagaag aaatatagtg
    30001 gatactcttt aacattaacc actccacctg actagccaat attctttttc gctcctacca
    30061 actcccaata actattttgg ctttatttcc agagtatttt atggtaaaat gaagagtaat
    30121 aatatttatt aaagaggtaa aaacatgatt gaagcaagta aattaaaagc tggtatgacc
    30181 tttgaaacag ctgacggcaa attgattcgc gttttggaag ctagtcacca caaaccaggt
    30241 aaaggaaaca cgatcatgcg tatgaaatta cgtgatgtcc gtactggttc tacatttgac
    30301 acaagctacc gtccagagga aaaatttgaa caagctatta tcgagactgt cccagctcaa
    30361 tacttgtaca aaatggatga cacagcatac ttcatgaata cagaaactta cgaccaatac
    30421 gaaatccctg tagtcaatgt tgaaaacgaa ttgctttaca tccttgaaaa ctctgatgtg
    30481 aaaatccaat tctacggaac tgaagtgatc ggtgtcaccg ttcctactac tgttgagttg
    30541 acagttgctg aaactcaacc atctatcaaa ggtgctactg ttacaggttc tggtaaacca
    30601 gcaacgatgg aaactggact tgtcgtaaac gttccagact tcatcgaagc aggacaaaaa
    30661 ctcgttatca acactgcaga aggaacttac gtttctcgtg cctaatctct agaaagaggt
    30721 cattctatgg gaattgaaga acaacttggc gaaatcgtta tcgccccacg tgtacttgaa
    30781 aaaatcattg ctatcgctac tgcaaaggta gagggtgttc actctttttc aaacagatca
    30841 gtgtctgata ccctttcaaa actttcactc ggccgtggca tttatcttaa aaacgtggac
    30901 gaagaactca cagcagatat ctatctctac cttgagtacg gagtaaaagt tcctaaggta
    30961 gcggttgcta tccagaaagc tgtcaaagat gccgtccgta atatggctga tgtagaactc
    31021 gctgctatca atattcacgt tgcaggtatc gtcccagata aaacaccaaa accagaattg
    31081 aaagatctat ttgacgagga cttcctcaat gactagtcca ctattagaat ctagacgcca
    31141 actccgtaaa tgcgcttttc aagctctcat gagccttgag ttcggtacgg atgtcgaaac
    31201 tgcttgtcgt ttcgcctata ctcatgatcg tgaagatacg gatgtacaac ttccagcctt
    31261 tttgatagac ctcgtttctg gtgttcaagc taaaaaggaa gaactagata agcaaatcac
    31321 tcagcattta aaagcaggtt ggaccattga acgcttaacg ctcgtggaga gaaacctcct
    31381 tcgcttggga gtctttgaaa tcacttcatt tgacactcct cagttggttg ctgttaatga
    31441 agctatcgag cttgcaaagg acttctccga tcaaaaatct gcccgtttta tcaatggact
    31501 gctcagccag tttgtagcag aagaacaata aaaagaaaaa gtgtttgata gatatcaaac
    31561 actttttctt tgcctcccac tatctaaaaa aatgataata gatataattg taaacaaaaa
    31621 tccagatagg ttttgcatga ttgagaaagt taaaaaaact atggcagaga atcgttaatc
    31681 tcagattgtc ggtagaacga taaacaaagg caaaaaagaa accaatcaga ctataatata
    31741 ataaactaat tggatctctg tgagatagta tcaaatgact aagcccaaag ataaggcctg
    31801 ataagatgac atctaaataa tacttggact agggaaagaa ggtattcata aaataccctc
    31861 tatcaagagt ctcctcaaaa acaggaccga tgattacagg caggacaaaa gataagatag
    31921 tcgataaaaa ggttggttgt ccatttgaaa gaaccacggt aaaatactca tcatgaatat
    31981 tcctatgatt aatcaaatga gcatagcgtg cccaaaaatt accgagaatc tgataaacca
    32041 cataagttgc aaataaggag aagacaaatg accagttcca gctctttttc tcaaagataa
    32101 agagcatctt tttctttttt aacctccaaa ttaatagaaa aggaaacttc ccactaatcc
    32161 cactgttaaa ataagagaat agacatcagc tcctaaccct aaaatgatcg tcacatacaa
    32221 tccaattgtt tgtggtaagt aaataggtag atagtaaaat aataagcaaa aatattccaa
    32281 attgtcttag tttctttgtg tttctcatcg tacttttttg aaagattacc ctgttcggaa
    32341 gccgtacttc caagcatcta tataagaatt aagtgcccct tgcctcatat aaggagcaaa
    32401 ttctctataa tataaccatc tactatatcc atcttcccaa acagcaagac cacctgaagt
    32461 ttgctccaag tcctcagttg aaataactgt aaatgtttct gtacctgtca ttgcaagtac
    32521 cttcttaaaa tagattgttg taggctcaca tttatagtat atttcttttt ttgtctattt
    32581 tatagtctat ctcctcaact gtcaattttt caacctgaat tgcatttttc cataaaaaat
    32641 gagacctttc tagtctcatt tagtcattct tagtattttc taaatctttg atagcgttct
    32701 tccagcaact cttctagcga tttttgtgaa agtctagcta gctccgtttg gagttctttt
    32761 ttaacattct taatcaattc tttactagaa agtcccgttt cagagatcac cttatccacc
    32821 acgtccattt ctaacaactc gtgtgaagtg attttcatca gttctgccgc ttccatggca
    32881 cgactgccgt ccttccatag aatggaagca aagccttctg gactgagaat agcatagata
    32941 gaattttcca gcatccagac acggtctgcg actgctagag ccagagcccc acctgaacca
    33001 ccttcaccga taatgatagc gataatagga actctcagat cactcatttc catgagattg
    33061 cgagcaatgg cttctccctg tccacgttct tccgctccca caccaggata ggcacctgct
    33121 gtattgataa aggtcacaac tggacggcca aacttttcag cctgtttcat caaacgcaag
    33181 gccttgcgat agccttctgg atgcggttgt ccaaaattcc gcttgaggtt atcttgtaaa
    33241 ctcttgcctt tttggatacc aaccactgtt acagcttgat caccaagcca gccaatacca
    33301 ccaacaactg caccatcatc acgaaaagaa cggtcaccgt gtaattggat aaagtcatca
    33361 aaaatgcctg tcgcaaagtc caaagttgtc aagtgactct gctcacgcgc ttctctgact
    33421 atttttgcaa tattcatcta ggactccctc catgcaatct gactaggcta gcaatcgtat
    33481 ctggcaaatc tcttctttta acgatagcat ccacaaagcc atgttccaat aggaattctg
    33541 ccttttggaa atcctcaggc aagctttcac gaaccgtatt ttcaatgaca cgacgcccag
    33601 caaaaccgac caagctctgt ggttcagcca gaataatatc gccttccata gcgaaagaag
    33661 ctgtcacacc accagtcgtt ggatctgtca aaatggtcag gtaaaagaga ccagcatttg
    33721 aatggcgttt aactgctgca gaaatcttgg ccatctgcat gagactcatg attccttcct
    33781 gcatacgggc tccaccagag gctgtgaaga gaacaactgg caactgttca accgtcgcat
    33841 actcaaataa gcgagtgatt ttttcaccta caaccgtacc catagaagcc atgataaagt
    33901 tggaatccat aatcccaaga gccacagtct gacctttaat aagagcagtt cctgtcacaa
    33961 cggcttcatc cagaccagtt ttttcacgca tagttgctag tttcttttga taaccaggga
    34021 aatgcaaggg atccttgctt tcaatccctg taaacaattc cttgaaggtt cccatatcaa
    34081 tcgtcaaaac caagcgttct tgggcagaaa tacgaaaggt atagctacag tgtggacaga
    34141 tacgctcact tcccagatcc ttctgataga tggtatgctt acaacccgga cactgagaaa
    34201 ataattcatc tggaacttct ggcttggctt gaggtttttc cctaatcgaa cgattgggat
    34261 tgattcgaat atacttatct tttttactaa atagagccat tgattcccct tttcggttta
    34321 aactcttgaa gtcattttat tctttttctt gatacttggg taaaaaggtt tccatcaaga
    34381 aggaagtatc ataatcccca gcaatgacat tgcgatctga aatgaggtca agctggaaat
    34441 ctgcatttgt ctgcactcct tcaatctcta attcataaag ggcacgttgc attttcatca
    34501 aagcatcaaa acgattttcg ccgtgaacga tgattttagc aatcatacta tcataataag
    34561 gcggaatggt atagcctgga taaactgctg aatccacgcg caagccaact ccaccacttg
    34621 gcagatagag attagtaatc ttacctggac ttggagcaaa gttaaaggct gggttttctg
    34681 cattgatacg acactcgatg gcatgaccgc gtaggacaat atcttcttgc ttaacagaca
    34741 aaggctgacc tgctgcaatg cgaatttgtt ccttaacgat atccacacct gaaacaaact
    34801 ctgttactgg atgttctact tgtacacgag tattcatctc catgaaatag aaattgccac
    34861 ttgcttcatc aagaagaaac tcaatggtcc ctgcattctc atagccaaca gactctgcag
    34921 ctcgaacagc cgcagcaccg atttcatggc gcaacgtttt tccgattgca atcgaaggac
    34981 tttcttccaa aaccttttgg ttattccgtt gaagagaaca atcccgttca cccaagtgaa
    35041 tcacatgtcc atgttcatct cctaggattt gaacctcgat gtgacgagct ggatagataa
    35101 cccgttcaat gtacatggca ccattgccat aattggcctt ggcttcacta gaggcagttt
    35161 caaaggcgaa aacgaggtct tctgtttttt caaccttacg aattccttta ccacctccac
    35221 ctgctgaagc cttgagcata acaggatagc caattttttc tgcaacaatc aaagcttcct
    35281 cagagttatg cacttctcca tctgaacctg gaatgacagg cacacctgct ttgatcatct
    35341 gagcacgcgc attgatcttg tctcccatca tatccattac atgaccagat ggaccgataa
    35401 acttgattcc cacctcttca cacatggtcg caaatttgga attttcgctg agaaatccaa
    35461 aacctgggtg aatggcttct gcctcagtca agactgcagc tgatagaacc gcattaatat
    35521 tgagataaga ctctgttgcc ttgccaggac cgatacaaac tgcttcatct gccaaaagcg
    35581 tatgaagggc ttccttatca gcagttgaat aaaccgccac cgttgcgatc cccaattcac
    35641 gtgccgcacg gataatacga accgcaattt caccacgatt ggcaattaaa atttttcgaa
    35701 acatggagaa cctccttagt tcccaattgc aaaagtaagg gtaccactgg ctgcaagctt
    35761 gccatccact tcagcctttg cttcaaccac agctatggtg ccacgacgtt ttacaaaagt
    35821 cgctgtcata accaattggt cgcctggtac aacttgcttc ttgaacttaa ccttatccat
    35881 accagcgtaa aagaccagtt ttcctttatt ttcaggtttt gataactcca acacaccagc
    35941 agtttgcgcc aaggcttcca taatcagaac acctggcata actgggtatt gaggaaagtg
    36001 gccgttaaag aaaggctcgt tgatggtcac atttttgata gcaacaatgg tatcctcgct
    36061 cacctccaag acacggtcca ctagaagcat aggataacgg tggggaaggg cttctttgat
    36121 tccttgaata tcgatcattt gatacgtacc aatcctttac caaactcaac catttcttcg
    36181 ttagagacga gaatttccgt taccacacca tccttaggag ctgggatttc attcatgact
    36241 ttcatggctt cgataattac caatgtttga ccttttttga cactatcacc aactgtaacg
    36301 aaggcaggtt tatctggtcc agcagccaag taaaccactc caacaagtgg actctctaca
    36361 agatttccct cagtagccac acttgcttca gctggagctg gaacttcttc tgctacagtc
    36421 tctgctggag cagatgtagg agctactgga ctcggtgttg ctagaacggg tgctggagcg
    36481 acttgagttg caacttcagg cacaggtctc gcttcattct tgctaaactg caactcatcc
    36541 gtcccatttt tataagaaaa ttctctcaaa cttgactggt caaattgagt catcaagtct
    36601 ttaatatcgt ttaaattcat acttatctat tctcccaacg tttgaaagca agaactgcat
    36661 tgtggcctcc aaaaccaaaa gtatttgaaa tagcgtatgg aatttctttc tccaagcctt
    36721 gtccataaac gacattagct tcgatataat ctgatacttc acttgtccca gctgtcattg
    36781 gtacaaagtt atgacgcata gcttcgatgg tgacgatagc ttctactgca cccgcagccc
    36841 ccagcaaatg tcctgtaaaa gacttggttg atgatacagg tacttcctta ccaagaacag
    36901 ctacgatagc accactttct cctttttcat tggcaggagt tgacgttccg tgagcattga
    36961 cataggctac ttgctctgga gaaatctcag cttcttccaa ggctagtttg atggccttga
    37021 tagctccctg accttctgga tgtggagaag tcatgtggta ggcatcacaa gtatttccgt
    37081 aaccaaccac ttcagccagg atagtagctc cacgtttttc agcgtgttca agactttcta
    37141 gaaccaacat ccctgaacct tcacccataa caaacccatt gcgatcctta tcaaatggga
    37201 tcgaagcacg agttggatcc tctgtagtag agagagctgt taaggcttgg aaaccagcga
    37261 tggcaaaagg tgtgatagaa gcttctgttc ctcccaccaa catcacatct tggaaaccaa
    37321 acttaatgga gcggaaggca tccccaatcg catcatttga tgaagagcag gcagtattga
    37381 tagatttaca aacaccgttt gcaccaaaac gcatggctac attcccagaa gccatatttg
    37441 gtaaagcttt tggaagagtc attggtttga cacgtttggg tcctttttca tgaagacgaa
    37501 gtacctgatc ttcaatttcc ttgattccac caataccaga tgcaacgata acaccaaaac
    37561 gatccctatt aagagcctct acatcaagat tggcatgatt tacagcctct tgggctgcat
    37621 acaaggcata taaagaatag ttatcaaaac ggttggtatc tttttttaca aagtatttat
    37681 cgaacggaaa atcttggatt tctgccgcat tatgcacatc aaagtcacta tgatcaaatt
    37741 ttgtaatgcc accaatgccg attttcccag ttgctaaact attccaaaat tcttctggtg
    37801 tatttccgat tggagatgtt actccataac ctgttaccac tactcgattt agtttcattc
    37861 ttttctcctc tagctttcgc tacatactta agccgccatc aatggcaatc acttgaccag
    37921 ttagataatc ttggcctgct aaaaatactg tcaaatctgc aacctgctct gcctgcccaa
    37981 attctttcat cggaatctga gctagtgtag cttccttaat cttatctgat aagatagctg
    38041 tcatatcaga ctcaatcatt cctggagcaa tcacattgac tcgtatattc cgactagcga
    38101 cctcgcgtgc cacagacttg gtaaagccaa tcaagccagc cttagaagca gcatagttag
    38161 cttgaccaat attccccatc aaaccaacaa cactagacat attaatgata gcaccttctc
    38221 tggctttcat catcggtttc aagactgatt gtgtcatatt aaaggcacca gtcagattga
    38281 ccttgagcac tttttcaaaa tctgcttctg tcatcttgag cataagagta tcttgggtaa
    38341 tccctgcatt gttgaccaaa acatctactg aacccagttc tgcaatagct tgatcaatca
    38401 tacgcttagc gtctgcaaaa tctgatacat ctcctgaaat gggaaccacc ttgataccat
    38461 agtttgaaaa ctcagcgagc aattcttctg agattacccc acgactgttt aagacaatgt
    38521 tggctcctgc ttgagcaaac ttgtgggcga tggcaagacc aattccacga ctcgaacctg
    38581 taataaagat atttttatgt tctagtttca tttttttcct ttcaaaactt ctacttattt
    38641 tagtctattt ttctaaaagt gctactaaac tcgcttgatc ttccacatga gctaagtgag
    38701 cagtttgatc aattttttta acaaaacctg acaagacttt ccctggtcca atctcgataa
    38761 agttgcttat gcctgcttct tgcatgaccc caatactttc atagaaacga acgggttcct
    38821 tgacctgacg cgtcaagagc tgagcaatgt cctctttttg catcacagca gcttctgtat
    38881 tgccgactag gggacaagta aaatctgaaa aacttacctg agctagagtt tcagctagtt
    38941 tctggctagc aggttcaagg agagcggtgt gaaagggacc tgacacctta agaggaatca
    39001 agcgtttggc acctgcttct tgcaaaagtt caaccgctcg atcaactgca accacttctc
    39061 cagcaatgac gatttgtgca ggtgtgttat agttggctgg agtaaccact ccaagttcag
    39121 aagctttttg acaggcttct tcaatgacct ctactggcgt attgagaact gctaccatct
    39181 tgccagagtc agcaggagcc gcttcttcca tataggctcc acgcttagct accaaggcaa
    39241 ccgcatcttc aaaatccaag gcgccgcttg acaccaaggc agagtattct ccaagagaca
    39301 aaccagcaac catatcaggc tgatagccct tttcttgcaa taaacggtag atagcaaccg
    39361 aagtcgctag aatggctggt tgcgtatagc gggtctgatt gagtttgtct tcttccgtat
    39421 cgatgagata acgcaaatca taaccgagca cctgactcgc tcgatcaatc gtttctttaa
    39481 caatcggata ctgatcatag aaatcccgtc ccatccctag atactgggca ccttgaccag
    39541 caaataaaaa ggctgtttta gtcatttctt acaactcctg tccagcgaga ggcttcttct
    39601 tgaattttct tagcggctcc gtaatacaaa tcttttagga tttcttcagc tgtttcttct
    39661 ttagaaacaa gccctgcgat ttgacctgcc atgacagagc caccatccac atcaccgtga
    39721 acaactgctt tggctagggc acctgctccc atttgttcaa agatttctaa atcaggatct
    39781 tcctgcttaa aggcatcttt ttcagccagt tcaaaatctc tagtcaactg atttttaata
    39841 gcacgaacag catgaccaaa gtgctgagct gaaatcgtag tatcaatatc ccttgctttt
    39901 aaaattttct ccttgtagtt tggatgggca ttcgactctt ttgcaactac aaaccgtgtc
    39961 cccacctgta cagcctctgc acctagcata aagccagccg cagcaccttc accatccgca
    40021 attcctcctg cagcaataac aggaatagat acagctgtgg ctacctgtcg caccaaggtc
    40081 atggttgtta atttaccgat atgcccccca gcttccattc cttctgcaat aacagcgtct
    40141 gcaccgattt tttccatgcg tttagctaaa gcgacactag gaacaacagg aataacgatt
    40201 atcccagctt catggaaacg ttccatatac ttgcttggat ttcctgctcc tgttgtgaca
    40261 actttaacac cttcttcaat aacgagatcc acgatatctt ccacaaaggg agataagagc
    40321 atgatgttga ccccaaaggg tttatcagtc aatgatttga ttttatcaat attggccttg
    40381 acaacttctt tcggggcatt tcccccaccg ataattccta atcctccagc cttggaaaca
    40441 gcccctgcca aatcaccatc agcaacccag gccatccctc cttggaaaat aggatagtca
    40501 atcttcaata attctgtaat acgcgttttc atagtgcctc caaccttcct tgcttacgta
    40561 atagttcgat ttcaccataa tttgacagtc aaactattac ctaaacaaga gggagtgggt
    40621 ttctccctac tccttctact aatattctgc ttattttgct tgctcttcaa cgtaagcaac
    40681 caagtcacca actgttttca agtcattttc tgcttcgatt tggatatcaa aagcatcttc
    40741 gatttctgag attacttgga acaagtccaa tgaatctgcg tccaaatcat caaaagttga
    40801 ttcaagtgtt acttctgatg cgtcttttcc aagttcttca acgataattt cttgtacttt
    40861 ttcaaatact gccatgatag gactccttta aaataaatag tttttttata acaatgtgtt
    40921 caccacatga ttacctaaat tgtaagaatg agcgtgcccc aggtcaagcc tccaccgaag
    40981 cctgatagaa gaacagtctg gctaccatct aaagggatga gaccttgttc tacacactct
    41041 gaaagtaaaa tcgggatact ggctgcactg gtattgccat attccatcat attggctgga
    41101 agtttggctc ggtcaacacc aatttttcta gccatcttat ccaaaatacg gtcattggct
    41161 tgatgaagta gcagataatc caagtctgtc acctctatag gagattcatc aatagtctgc
    41221 ttgatagact tggctacatc tcgaatggca aaatcaaaga ctgtgcgtcc atccatcttc
    41281 aaaaatgaat ctgcactttc ttgatctgaa aatggagaat gcaaacctga atgcccataa
    41341 gttaaacact cgctgcgact tccatcgcta ttgagactct cagctaagaa atgctcttgc
    41401 tcgctagctt ctaacaagac accaccagca ccatctccaa acaacacagc tgttgatcga
    41461 tccgaccaat cgactgcctt agagagggtt tcactaccaa tcaccaagcc tttttgaaag
    41521 cgaccagaag cgataaactt ttcagcagtt gaaagagcaa atacaaatcc actgcaagct
    41581 gcggttaagt caaaagcaaa ggctttatta gcaccaatat tagcttgaac acgagcagct
    41641 gtagagggca tcatcgaatc tggagtaatg gtagctagga tgataaaatc cagttcctct
    41701 cctattattc cagcttttgc catcagtttc ttagcaacct ctgtagccaa atcactggta
    41761 gattctgttc ttgaaatatg cctttgtcgt attcccgttc gacttgaaat ccactcatca
    41821 ttggtatcca taatctgagc caagtcgtga tttgtaacca cttgctctgg aacataatga
    41881 gcaacctggc ttatttttga aaaagccatt atttcaaatc ctccaaaaat tggtaaagat
    41941 tagtcaaacc tttacccatg acagcaattt cttcctcgct catgccatca ataatttttt
    42001 ctaccatggc cttgtggaag cgtttatgca gtctatgaat caagcgaccc ttctttgtca
    42061 aatgcagatg caccacacga cgatcctgtt ctgaccgaac tcgctcaatg tagcccttac
    42121 gctctaaatt gttcaaactt gtcgtaacag ttccaagagt taccatcaac tcttttgaca
    42181 cttgacttgg agtcacgtct ggagccttac cgataacatc aatcgtatgc atttctttga
    42241 tggagatatc cttaaaacga ctacctctca agttcacttc ctcaatcaca aggacattgt
    42301 taaatataga tgttaaatat tcattgattc gttggtagtc catttttcat atccctcctt
    42361 cttcaaaaaa cttttacaat caaaacattt gacaaaaaga attatatcaa aattcaaaga
    42421 atgatgcaag tattttttat tttcctgtaa atttaggtct tcttctctcc gaatgagct
//
LOCUS       DAVDZK010000015        42320 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVDZK010000015 DAVDZK010000000
VERSION     DAVDZK010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42320
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.015"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(117..2669)
                     /locus_tag="VUX16_000948"
     CDS             complement(117..2669)
                     /locus_tag="VUX16_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET8123933.1"
                     /translation="MKSFLKTYRIYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(2731..4353)
                     /locus_tag="VUX16_000949"
     CDS             complement(2731..4353)
                     /locus_tag="VUX16_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET8123934.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            4559..5584
                     /gene="trpS"
                     /locus_tag="VUX16_000950"
     CDS             4559..5584
                     /gene="trpS"
                     /locus_tag="VUX16_000950"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET8123935.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQNIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            5736..7214
                     /gene="guaB"
                     /locus_tag="VUX16_000951"
     CDS             5736..7214
                     /gene="guaB"
                     /locus_tag="VUX16_000951"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET8123936.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(7265..8362)
                     /gene="recF"
                     /locus_tag="VUX16_000952"
     CDS             complement(7265..8362)
                     /gene="recF"
                     /locus_tag="VUX16_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET8123937.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGYRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQNGKAAVNGN"
     gene            complement(8365..8733)
                     /gene="yaaA"
                     /locus_tag="VUX16_000953"
     CDS             complement(8365..8733)
                     /gene="yaaA"
                     /locus_tag="VUX16_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET8123938.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            8892..10142
                     /locus_tag="VUX16_000954"
     CDS             8892..10142
                     /locus_tag="VUX16_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET8123939.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSQLDLFSGFLRMYAGIDRENRNQARKMMNNQLLDL
                     KKGYFTELELEQTKEMIRRSLLLSQDNQGSLIERAYQNALLGKSSADFKSWITKLEQV
                     DKDDICRAANNVKLQAIYFMEGIE"
     gene            10139..11422
                     /locus_tag="VUX16_000955"
     CDS             10139..11422
                     /locus_tag="VUX16_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET8123940.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTLVTEVDGDVKEYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTSYLFSATDHFLENLDLLDELVTSAHFTEASILREQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTRFYKPVNMSLFLVGDFDVELV
                     QGYFERKELKDLDVQEVVREKFVLQAVKQTDSMRMEVSSPKLAIGVRGKREVAEADCY
                     RHHVLLKLLFAMMFGWTSDRFQKLYESGKIDASLSLEIEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            11464..12285
                     /locus_tag="VUX16_000956"
     CDS             11464..12285
                     /locus_tag="VUX16_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET8123941.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKGPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            12296..12841
                     /gene="pgsA"
                     /locus_tag="VUX16_000957"
     CDS             12296..12841
                     /gene="pgsA"
                     /locus_tag="VUX16_000957"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET8123942.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            12838..13665
                     /locus_tag="VUX16_000958"
     CDS             12838..13665
                     /locus_tag="VUX16_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET8123943.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALDLVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            13650..14489
                     /locus_tag="VUX16_000959"
     CDS             13650..14489
                     /locus_tag="VUX16_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET8123944.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            14482..15276
                     /locus_tag="VUX16_000960"
     CDS             14482..15276
                     /locus_tag="VUX16_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET8123945.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            15335..16153
                     /gene="mreC"
                     /locus_tag="VUX16_000961"
     CDS             15335..16153
                     /gene="mreC"
                     /locus_tag="VUX16_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET8123946.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSISKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            16153..16647
                     /gene="mreD"
                     /locus_tag="VUX16_000962"
     CDS             16153..16647
                     /gene="mreD"
                     /locus_tag="VUX16_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET8123947.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            16741..17919
                     /locus_tag="VUX16_000963"
     CDS             16741..17919
                     /locus_tag="VUX16_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET8123948.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            18143..18922
                     /gene="rpsB"
                     /locus_tag="VUX16_000964"
     CDS             18143..18922
                     /gene="rpsB"
                     /locus_tag="VUX16_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET8123949.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            19001..20041
                     /locus_tag="VUX16_000965"
     CDS             19001..20041
                     /locus_tag="VUX16_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET8123950.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            20287..20610
                     /gene="tnpB"
                     /locus_tag="VUX16_000966"
     CDS             20287..20610
                     /gene="tnpB"
                     /locus_tag="VUX16_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET8123951.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(20751..21059)
                     /locus_tag="VUX16_000967"
                     /pseudo
     CDS             complement(20751..21059)
                     /locus_tag="VUX16_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21050..21448
                     /locus_tag="VUX16_000968"
     CDS             21050..21448
                     /locus_tag="VUX16_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET8123952.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(21645..22565)
                     /gene="cysK"
                     /locus_tag="VUX16_000969"
     CDS             complement(21645..22565)
                     /gene="cysK"
                     /locus_tag="VUX16_000969"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET8123953.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(22850..23485)
                     /locus_tag="VUX16_000970"
     CDS             complement(22850..23485)
                     /locus_tag="VUX16_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET8123954.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYASSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            23541..24839
                     /locus_tag="VUX16_000971"
     CDS             23541..24839
                     /locus_tag="VUX16_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET8123955.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            24836..25498
                     /locus_tag="VUX16_000972"
     CDS             24836..25498
                     /locus_tag="VUX16_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET8123956.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQFWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            25578..26126
                     /gene="raiA"
                     /locus_tag="VUX16_000973"
     CDS             25578..26126
                     /gene="raiA"
                     /locus_tag="VUX16_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET8123957.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            26262..28235
                     /locus_tag="VUX16_000974"
     CDS             26262..28235
                     /locus_tag="VUX16_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET8123958.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDHVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            28232..28684
                     /gene="rplI"
                     /locus_tag="VUX16_000975"
     CDS             28232..28684
                     /gene="rplI"
                     /locus_tag="VUX16_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET8123959.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            28728..30080
                     /gene="dnaB"
                     /locus_tag="VUX16_000976"
     CDS             28728..30080
                     /gene="dnaB"
                     /locus_tag="VUX16_000976"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET8123960.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            30082..30348
                     /locus_tag="VUX16_000977"
     CDS             30082..30348
                     /locus_tag="VUX16_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123961.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            30437..31783
                     /gene="cbpD"
                     /locus_tag="VUX16_000978"
     CDS             30437..31783
                     /gene="cbpD"
                     /locus_tag="VUX16_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET8123962.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      31866..31968
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            32039..32329
                     /locus_tag="VUX16_000979"
     CDS             32039..32329
                     /locus_tag="VUX16_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET8123963.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            32292..33050
                     /locus_tag="VUX16_000980"
     CDS             32292..33050
                     /locus_tag="VUX16_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8123964.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWFNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            33089..34096
                     /locus_tag="VUX16_000981"
     CDS             33089..34096
                     /locus_tag="VUX16_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET8123965.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            34096..34824
                     /locus_tag="VUX16_000982"
     CDS             34096..34824
                     /locus_tag="VUX16_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8123966.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            34943..35401
                     /locus_tag="VUX16_000983"
     CDS             34943..35401
                     /locus_tag="VUX16_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET8123967.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            35403..37835
                     /locus_tag="VUX16_000984"
     CDS             35403..37835
                     /locus_tag="VUX16_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET8123968.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            38156..38809
                     /gene="rr06"
                     /locus_tag="VUX16_000985"
     CDS             38156..38809
                     /gene="rr06"
                     /locus_tag="VUX16_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET8123969.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            38806..40146
                     /gene="hk06"
                     /locus_tag="VUX16_000986"
     CDS             38806..40146
                     /gene="hk06"
                     /locus_tag="VUX16_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET8123970.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            40229..40756
                     /locus_tag="VUX16_000987"
     CDS             40229..40756
                     /locus_tag="VUX16_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET8123971.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            40835..>42320
                     /gene="pspC"
                     /locus_tag="VUX16_000988"
     CDS             40835..>42320
                     /gene="pspC"
                     /locus_tag="VUX16_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HET8123972.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGN
                     NSTVTSSGQDISKKYADEVESHLQSILKDVNKNLKKVQHTQNADFNKKLSKIKTKYLY
                     ELNVLEEKSEAELTSKTKETKEELTAAFEQFKKDTLSTEPEKKVAEAKKKVEEAKKKA
                     EDQKEEDRRNYPTNTYKTLELEIAESDVEVKKAELELVKEEAKEPRNEEKVKQAKAEV
                     ESKQAEATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPE
                     KPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPK
                     TGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGS
                     MATGWLQNNGSWYYLNANGSMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNAN
                     GDMATGWLQNNGSWYYLNANGSMVTGWLQYNGSWYYLNANGSMAT"
BASE COUNT        13338 a         6909 c         9164 g        12909 t
ORIGIN      
        1 tcttagttca tagatctgaa ctttatcttc ataactcaat ttcataataa aacaccccaa
       61 aagttagatt ttttctgtct aacttttggg gtgcagttca ttaactagtc gattttttat
      121 gccttagatg actttcgtct gtgattatag attccaaata gtaagagaga agtaaaggaa
      181 cagattgctc cagtaataaa accattggga atgaaggaaa gtgtaatagt tcctttcccc
      241 ttgggaatgt caactttcat aaatccagtt tgagcttgtt taatttctat tttcttacca
      301 tcttggtagg cagaccaacc tttgtcataa ggaatggtga agaaaataga tgtatcttgt
      361 tggacatcat atgtagcaaa aaccttgttt ttagaagttg atactgtgac aggttgttct
      421 ttaatttttt gaattgcctc ggtgaaagtt ttggtatcta aacgatagaa ggtaggagat
      481 tcaaatgata cttgtgaatt tccagggaaa ctaacattga tattgaaagt ttttttctct
      541 ttagtatatc ctagattaaa gaaggagaag acattatcag ttgtaaaagt ctttttttca
      601 ccatttacaa ggatgtcaac cttcttttgt ttatcgttag aaaagtgaag gtttatgaaa
      661 gagagataaa cttggctgtt ttctggaact tcaatttgat actggattgc tgcatcttca
      721 tttgaagaac ttgtgacact aatcaaatca ttagtatttt ctattttttc tgttttttca
      781 taaggtattg gagaaaaata atcaaaattg acgttagcaa gttgatttaa aaatgaggcc
      841 tgattatcca aggtatgttc attgaacttg acatcattgt aaacagattg actagcaact
      901 gcaatcggaa gagagtattg attttcatat agggtaagat tatctttttg atagatatct
      961 ttaaagccat acttatcgat aggactgtct gagatattgt actggatacc aaataaacta
     1021 tcagccaaaa tactattatt tgcatatcgg agattgagat tagtcccaga ggatttaaaa
     1081 ccaagtttat ctaaagtaga gcttgatgaa cgatttcgaa cagatgaaaa ttgagagatt
     1141 ccattgtagt tgaatttcat actgtcattt cctgtctgag tttgtagttt ttcagtacga
     1201 gtaaattgat ttccaatata tgttgagaaa gattccatag ctgggatatc tcgactataa
     1261 gcacttcgag aagcaaatcc ccattcctta gcaattccgt ccatttgaga tgaagcattt
     1321 aaactcattt caaccagtat aaataaagag attagaatgg caaatagatt cacagatata
     1381 aactttttga taactgcaag gagtaaaaga gaatagacaa ccaaaaattc aagagtaagc
     1441 agaatattca aatctgttaa aaaagaataa tgcgatttta gatagatggt agctaaaaat
     1501 cctgctacta caagaaaaag cgaaactaaa aaattccaga ctttaagttc tttcagacgc
     1561 tttaagactt ctgctgctgt gtaaattaac aaggtagaga aaatccaagc atagcgatgt
     1621 aaaaacatgt ttggagtatg catgccttgc caaaataagt caagagcttc tatgtaaaag
     1681 cttgcaatta gaaatgcaaa gaatattaca tatatgagtt tcacgtgaaa cttaatagat
     1741 ttcagcgtaa aaaataaaat ggtcaaaata aagggaagta gtccaacaaa aatcattggg
     1801 atggccccat actttgttgt gtcaaaggaa ccaatgaatt gcttagcaaa gagatcaaga
     1861 taccagctac tttcagtttg aaactttgta acttcagtca atttttcccc atgtgtctgt
     1921 aaatcaaata gagtgggaag agtcataatc aaactagcca taccagctaa aaaggagata
     1981 actatgaaat caagaacaga tgattttcga gtcttaaagt cccacgaaat ttgacagaga
     2041 taccagaaaa taagaaacaa tactgtcata tatccaaaat aataattttg aataaataag
     2101 attgacagac ttgtaaagta caataggagt ttcttttcag ttatcagtag atgtaaacca
     2161 gttataatta aaggaatcaa gataaaaaca tctagccagg tttttatctc taattgactg
     2221 acagtgaaac tcatcagagc ataggaagta gataaggcta gttttaaagt ctgagggata
     2281 gattgaaaca atttattcaa actaaaaaag gttgacagac caatcaatcc aaattttaag
     2341 agagtggtca gatagacagc atctggcata ttcgttagat caaaaaagta aactagaggc
     2401 gcgagaaaac tacccaagta ataactagat agggcataga agtttagccc tagaccactt
     2461 gtaaaggtgt aaaacagact actatttcca tgtaggatat ttcgtaaggc tacatcaaaa
     2521 ataacgtatt gatgaaagcc atctcctaat agaggagagt tgtcgctatt ccagtagata
     2581 ccttgagata gatatactcc agacataatc actacaggaa tgatgaaaga aataaaatag
     2641 attcgatatg tttttaaaaa tgatttcatg ttacctcgta gaatgataga aaactcagtt
     2701 ggttaaccca actgagtttt gaagttttat ttagtctttc caaagttctt taacttttgc
     2761 ttgtacttct gcattttcta ggaattcatc gtaggtttca tcgatacggt caatgacgcc
     2821 atttttagat aagacaatga tatggttagc caaagtttga ataaactcgt ggtcatggct
     2881 ggcaaagatg attgattctt taaagttttt caatccatca ttcaagcttg agatagattc
     2941 caagtccaag tgatttgttg gatcatcaag tacaaggaca tttgatttta agagcatgag
     3001 ttttgaaagc atgacacgaa ctttttctcc ccctgacaag acatttacag gtttgttaac
     3061 ttcatctcca gagaagagca tacggccgag gaaaccacgt aggaaagtat tgtcatcttc
     3121 ttctttactt gcgaattgac gcaaccagtc aagaattgat tctcctcctg caaaatcagc
     3181 tgagttatct tttggtaggt aagattgact agttgtaact ccccacttga cagttccttc
     3241 atagtcaata tctcccatga ttgcacgaat taatgcagtc gtttgaatat cattttgtcc
     3301 aataagtgcc gtcttatcat ctggacgcaa gatgaaacta atattatcca agatagtttc
     3361 accatcaatc tttacagtta gattttctac tgtcaagaga tcattaccaa tctcacgttc
     3421 cgctttaaag ttgataaatg gatatttacg actagatggt acaatctctt ctagctcaat
     3481 cttatcaagc attttcttac gtgatgttgc ctgccttgac ttagaagcat tggcagagaa
     3541 acgagcaacg aattcttgca attgtttaat tttttcttct gctttagcat tacggtctgc
     3601 tagcaattta gcagcaagct cagaagattc cttccagaag tcgtagtttc cgacatagag
     3661 tttgattttt ccaaagtcaa ggtcggccat gtgagtacaa actttgttta agaagtgacg
     3721 gtcgtgggat actacgataa ctgtgttatc aaagtcaatc aagaagtctt ctaaccaagt
     3781 aatcgattgg atatccaaac cgttagtagg ctcgtccaag agaagaacat ctggtttacc
     3841 aaaaagtgct ttggcgagga gaacctttac tttttcaccg ttggccaatt cgctcatgtt
     3901 ttggtagtgt aattcttctg gaatgtttag gttttgaagt agttgagagg cttcactctc
     3961 tgcttcccaa cctccaagtt cggcaaattc tccttcgagt tcggcagcac gaaccccgtc
     4021 ctcgtctgag aaatcttcct tcatgtagat agcatctttc tctttcatga tgctataaag
     4081 tttttcattt cccatgataa cgacatcaat ggcacgttca tcttcgtagt caaagtgatt
     4141 ttgacgaaga acagagagac gttcatctgg accaagagag atgtgaccag tagtaggttc
     4201 gatatctcca gctaaaattt ttaaaaaggt tgattttccg gcaccattag caccgattaa
     4261 tccgtaagta tttccttctg taaatttgat attgacatca tcaaaaagtt tgcgatcact
     4321 aaaacgtagt gaaacatcag atactgtaag caatattttt ctcctatatg tgtaatatat
     4381 ttattatact agaaaataca gaaatattca aatttttatt tgtcaatttt gtgtaaatta
     4441 tatttacagt atcctttaca caaatctgta aaaagcaagg ctgatttatt ttgataaatt
     4501 acggttattt cattaaaaaa atgctataat tgaaaggact atatcgaagg agaacaaaat
     4561 gactaaaccc attattttaa caggagaccg tccaacagga aaattgcata ttggacatta
     4621 tgttggaagt ctcaaaaatc gagtattatt acaggaagag gataagtatg atatgtttgt
     4681 gttcttggct gaccaacaag ctttgacaga tcatgccaaa gatcctcaaa acattgtaga
     4741 gtctatcgga aatgtggctt tggattatct tgcagttgga ttggatccaa ataagtcaac
     4801 tatttttatt caaagccaga ttccagagtt ggctgagttg tctatgtatt atatgaatct
     4861 agtttcgtta gcacgtttgg agcgaaatcc aacagtcaag acagagattt ctcagaaagg
     4921 atttggagaa agcattccga caggattctt ggtctatcca atcgctcaag cagctgatat
     4981 cacagctttc aaggctaatt atgttcctgt tgggacagat cagaaaccaa tgattgagca
     5041 aactcgtgaa attgttcgtt cttttaacaa tgcatataac tgtgatgtct tggtagagcc
     5101 ggaaggtatt tatccagaaa atgagagagc agggcgtttg cctggtttag atggaaatgc
     5161 taaaatgtct aaatcactaa ataatggtat ttatttagct gatgatgcgg atactttgcg
     5221 taaaaaagta atgagtatgt atacagatcc agatcatatc cgcgttgagg atccaggtaa
     5281 gattgaggga aatatggttt tccattatct agatgttttt ggtcgtccag aagatgctca
     5341 agaaattgct gatatgaaag aacgttatca acgaggtggt cttggtgatg tgaagaccaa
     5401 gcgttatcta cttgaaatat tagaacgtga actgggtcct attcgtgagc gccgtattga
     5461 atttgctaag gatatgggag aagtttataa tatgattcaa aaaggtagtg aaagagcgcg
     5521 tgaagttgcg ggtcaaaccc tatctgaggt aaaaggggca atgggacttc attactttaa
     5581 ctaagtttat tttacaagaa actatcattt ctatctcgaa gaaaagatag ttttttattt
     5641 acccctgtaa catttgacaa atttttatag aatggtatga tagatacaat ataaaaagaa
     5701 tcaagctcaa aaagaaagaa aagaggaaac ttcgaatgtc taattgggac actaaatttt
     5761 tgaaaaaagg ttttaccttt gatgatgtat tgcttattcc agctgaaagt catgtgttgc
     5821 ctaacgatgc agatttaaca actaaattgg cagataattt gactttaaat atcccaatta
     5881 ttaccgctgc catggacaca gttacagaga gtcaaatggc cattgctatt gctcgtgcag
     5941 gtggtctcgg agttatccat aaaaacatgt caattgctca acaagcagac gaggttcgta
     6001 aggtaaaacg ttctgaaaat ggagttatta ttgatccgtt cttcttgacg cctgaacata
     6061 caattgctga agcagatgag cttatgggtc gttaccgcat cagtggtgtt ccagttgttg
     6121 aaacacttga aaatcgtaaa ttggttggta ttttgacaaa ccgagatctt cgttttattt
     6181 cagattataa tcaaccaatt tcaaaccata tgactagtga aaatcttgtt actgctcctg
     6241 tgggtacgga tcttgcaacg gctgagagta ttcttcaaga gcatcgtatt gaaaaacttc
     6301 cgttggtcga tgaagaaggc agtctttctg gtttgatcac tatcaaagat attgaaaaag
     6361 ttattgagtt tccaaatgcg gctaaagatg agtttggtcg tcttctagtt gcaggtgcag
     6421 taggtgttac ttcagataca tttgaacgtg cagaggctct ttttgaggca ggagcggatg
     6481 cgattgttat tgatactgca catggtcatt ctgcaggtgt cttgcgtaaa attgccgaga
     6541 ttcgtgctca tttcccagat cggactttga ttgctggaaa tattgctact gctgaaggtg
     6601 cacgtgccct ttatgaagcg ggtgtagacg ttgttaaggt tggtattgga ccaggttcta
     6661 tctgtactac tcgtgtgatt gctggtgttg gtgttccgca agtaacagct atctacgatg
     6721 ctgcagctgt tgcgcgcgaa tatggtaaaa cgattattgc tgacggtggg atcaagtatt
     6781 ctggagatat tgtaaaagca cttgctgcag gtggaaatgc tgttatgctt ggatctatgt
     6841 ttgctggaac tgatgaagct ccaggcgaaa ctgaaatctt ccaaggacgt aaattcaaga
     6901 cttaccgtgg tatgggatca attgctgcta tgaagaaagg ttcaagcgac cgttatttcc
     6961 aaggttctgt caatgaagca aacaagctcg ttccagaagg aattgaaggt cgtgttgctt
     7021 ataaaggagc ggcagctgat attgttttcc aaatgattgg tggtattcgc tctggtatgg
     7081 gttactgtgg tgcagctaac cttaaagaac tacacgataa tgctcaattt attgaaatgt
     7141 ctggtgctgg tttgaaagaa agccatcctc atgatgtgca aattactaat gaggcaccaa
     7201 attattctat gtaaaaaaca atgaaaagaa ctccagtgaa aacaggagtt cttttacaat
     7261 gttgtcaatt tccatttaca gcagctttac cattctgaat agtgaagata cttagatttt
     7321 ctggcagatt ttgaagatgg tctaagcttg ttgttgtgat aaaggtttgg attgattgag
     7381 aaatcgtttc taataatttt aactgtctag tgttgtcaag ttcactcatc acatcgtcaa
     7441 gcagtaatat cggagattct gtggtaatgc tttccattaa ttcgatttct gctaatttta
     7501 tagagaggac gagactacga tgttgacctt ggcttccgaa actagcatcc atcccattta
     7561 tataaaaaga aatgtcatct cgatgaggac cgacaccagt attcttttta aataaatctc
     7621 tggatctact tttttctaaa gcaattttga aagattcgga taagttttgt ttgtcagtta
     7681 tattgacaga agattgatag gatattgaca actcttcgat ctgattagag agttcaaaat
     7741 gtttcttacg cccaaatgat tctagttttt ttatgaaatc taagcggtga ttcattacac
     7801 gatatccata atcaactagc tgatcatcta acacagaaag gaatgtttca tctatttttt
     7861 gagctgattt taggtaagtg tttctttgct ttaggatgtg gttataattg gttaagtcag
     7921 ataagtagat tggcttaatt tgcccaagtt ccatatcaat gaattttcgt cgaatcgaag
     7981 gtgctccttt aattagttgt aaatcttcag gagcaaataa gacaacattc atgtgtccta
     8041 cataatctga aaggcgtgcc tgttttaagt gattaacttt tgttacacgg cctttttgtg
     8101 ttagttcgat ttctagggga atggatccag tttttttctg aacgagacct gaaagatgaa
     8161 gttgttcctc atcaaaatga atgagatttt tatctgttcg agttcgatga ctacgcgtta
     8221 aggctaaaaa atagatagcc tctaacatgt ttgtttttcc ttgtgcatta cgtcccaaaa
     8281 agacattcaa tttaggatta aagtctattt tcgtttcttt gtaattacga aaagtcttga
     8341 gagatagatg ttgtagccac atgattatct accagggaat cgtggagctt gttggctttt
     8401 aggtgatgaa gcaggtttcg atttgtcttt tttaactccc ttattcatct ttttgacaag
     8461 tttagcgatc cgttcttttt caactttatc agcttggtat tcatcttgtt cttcagaagt
     8521 aggttgtgtc aacaagatgt caatgttcat gtcagggatg tcaactttat cgccaatacg
     8581 aagttttttt ccacgacgac tctctaattc cctattaaag taaacagaat gttcagagag
     8641 aaatgattta atagctcctc cgctatgtgt aattccaagt tctttgagta gtgcttggag
     8701 ggtaataaat tcttcaaata atttgtattc cataattcac ctcaatcttt ggtattatac
     8761 catattttcc taaaaatagt gagagagaca gcgagaaatg taagcgattt ttatttcaaa
     8821 agtgttacag ggaacaagaa aatttcaggt tttcgtgata taatagaagt ctgtatataa
     8881 ggaggtaaat catggagtta gtgcatggaa tttcaacaca ttttatccaa tcaaaaaagt
     8941 ttaaaacaaa caaaattacc gtgcgtttta ccgctccatt atcccttgat acgattgcag
     9001 gtcacatgtt gagtgcaagt atgctagaga ctgctaatca gatgtacccc acttctcaag
     9061 atttgaggag acacttggcc agtctatacg gtacagatat gtcaaccaat tgtttcagaa
     9121 gagggcaaag ccacattata gaattgacat ttacctatgt tcgtgatgag tttttaagta
     9181 ggaaaaacgt gctaacttct cagattttgg aacttgtaaa agaaactctt ttttcacccg
     9241 tagtagttga taatgggttt gatccggcct tatttgaaat tgagaaaaaa caattgctag
     9301 caagtttagc agctgatatg gatgattctt tttattttgc acataaagaa ttggataaat
     9361 tgttttttca tgatgaacgt cttcaattgg aatatagtga tttacgaaat cgtattttag
     9421 ctgaaactcc acaaagttct tattcttgtt tccaagaatt tttagccaat gatcgaatag
     9481 atttcttttt cctaggtgat tttaatgagg ttgaaattca aaatgtatta gaatcatttg
     9541 gctttaaagg tcgaaaagga gatgtgaagg ttcagtattg tcaaccttat tctaatatcc
     9601 ttcaggaagg tatggttcgg aaaaatgtgg gacaatctat tttggaatta ggttatcatt
     9661 accgttctaa atatggtgat gagcaacatt tacccatgat tgtaatgaat ggtttacttg
     9721 gtggatttgc tcactctaag ctctttacaa atgtccgtga aaatgctgga ttggcttata
     9781 ctatttcaag tcagcttgat ttatttagtg gatttttgag gatgtatgct ggtattgatc
     9841 gagaaaatcg gaatcaggct cgtaaaatga tgaataatca actgcttgat ttaaaaaaag
     9901 gttattttac agagcttgag ttagagcaga ccaaggaaat gattcgtcgg tctttgttac
     9961 tttctcaaga taatcaaggt tcattgattg aacgtgctta tcaaaatgcc ttacttggaa
    10021 aatcttcagc agactttaaa agttggatta caaaactcga gcaagttgat aaagatgata
    10081 tttgtagagc agctaataat gtgaaactac aagcgattta ctttatggaa ggaatagaat
    10141 gacaaaggtt gtttttgaag aaaaatacta tccagctgta aaagaaatgg tttatcgaac
    10201 tcgtttggcc aacggattga cagttgctct tttgcctaaa aaggaattta aagaggttta
    10261 cgggagtgta actgtacaat ttggttcggt agatacgctt gtcacagaag ttgacggaga
    10321 tgtaaaagaa tatcctgcgg gaattgctca ttttcttgaa cataaattat ttgagagaga
    10381 agattctagt gatttgatgt ctgcttttac gagtctaggt gcagatagta atgcctttac
    10441 aagctttaca aaaacaagtt atcttttttc agcaacggat cattttttag aaaatttaga
    10501 tttacttgat gaattggtaa catcagcaca ctttactgaa gcttccattt tgagagagca
    10561 ggatattatc cagcaagaac gagaaatgta tcaagatgat ccagattcgt gtttattctt
    10621 ttcaacttta gcgaatttgt atcctggtac acctttagca acggatatag ttggaagtga
    10681 ggagtccatt tcccaaatca atctaactaa tttgcaagaa aattttacaa gattttacaa
    10741 acctgtaaac atgtctctgt ttttagttgg tgattttgat gtagagctag ttcagggtta
    10801 ctttgaaaga aaagaactga aagacttaga tgttcaggaa gtagtaagag aaaaatttgt
    10861 tttacaggct gtaaagcaaa cagacagtat gagaatggaa gtatcttctc ccaaactagc
    10921 gattggagtt agaggtaagc gagaagttgc tgaggcggat tgctatcgac atcatgtttt
    10981 attaaaatta ttgtttgcaa tgatgtttgg ttggacttcg gatcgttttc aaaagttata
    11041 tgaatcaggt aaaatagatg cttccttatc tcttgaaatt gaagtaacaa gtcgttttca
    11101 ttttgtcatg ttgacaatgg atacgaaaga gccagttgct ttgtctcatc aatttaggaa
    11161 ggctattcgt aattttacaa aggatttaga tattacagag gaacatttag atattatcaa
    11221 aagagagatg tttggcgaat ttttcagtag catgaactct cttgaattta ttgcaacgca
    11281 atatgatgct tttgaaaatg gtgagacaat ttttgatttg ccgaaaattt tacaggaaat
    11341 tactttagag gatgtccttg atgctggaca tcatttaata gatgatggtg acatagttga
    11401 ttttacaata ttcccatcgt agtaacctat tataatagac actagaaaga agggatgaca
    11461 agtatgagaa aaaaaacaat tggagaggtt ttacgattag ctagaatcaa tcagggattg
    11521 agtttagatg aattgcagaa aaagacagaa atccagttag atatgttgga agcaatggaa
    11581 gcagacgatt tcgatcaact tccaagtcct ttttacacgc gttctttctt gaaaaaatat
    11641 gcatgggctg ttgagttaga tgaccaaatt gttttggatg cttatgattc tgggagtatg
    11701 attacttatg aggaagtaga tgttgatgaa gatgagttga caggtcgtag acgttcaagt
    11761 aagaaaaaga agaaaaaaac atcattttta cctttatttt attttatcct ttttgcttta
    11821 tcgattttaa tttttgtgac ttattatgtt tggaactata ttcaaactca accagaggag
    11881 ccttctcttt ctaattacag tgtggttcaa tcaacaagtt caactagctc tgttccccac
    11941 tcctcaagta gtagttcttc tagtatagaa tcagctataa gtgtatcagg cgaaggaaat
    12001 catgtagaaa tcgcttataa gacaagtaag gaaacagtta aattgcaatt ggcagtttca
    12061 gatgttacaa gttgggtcag tgtttcagaa agcgaacttg agggcggtgt aaccttatcg
    12121 ccaaagaaga aaagtgcaga agcaacagtt gcaactaaag gtcctgtaac aattacgtta
    12181 ggtgttgtaa aaggtgttga tttgacagta gataatcaga ctgttgattt atcgaaatta
    12241 acagctcaga ctggacaaat cactgtaacc tttactaaaa attaaggaaa aacgaatgaa
    12301 aaaagaacaa attcccaatc tcttaacaat aggtcgaatt ctctttatac ctatttttat
    12361 ctttatttta acgataggaa attcgataga gagtcatata gttgcagcta ttatctttgc
    12421 tgttgccagt attaccgact atttagatgg atatttagct cgtaaatgga atgtggtcag
    12481 taattttggt aaatttgcag atcctatggc ggataagtta ctagttatgt cggcttttat
    12541 tatgttgatt gagttaggta tggctccggc ttggattgtt gcagtgatta tctgtcgtga
    12601 gttagctgtg acaggtttaa ggcttttatt ggttgaaact ggtggaacaa ttttagcagc
    12661 agcaatgcct ggaaaaatta aaacttttag tcagatgttt gctattattt tcttgctatt
    12721 acattggact ttgcttggtc aagttctact ttatgtagcc ttatttttca ctatctactc
    12781 tggctatgac tatttcaagg gtagtgccta tgtatttaaa gggacatttg gttcgaaatg
    12841 aaatcaataa ttgatgtaaa aaatctttct tttcgctata aagaaaatca gaactactac
    12901 gatgtgaagg atattacgtt tcacgtgaaa cgtggagaat ggctttcgat tgtagggcat
    12961 aatggtagtg gtaaatcaac gacggttcga ttaattgatg gcttactgga agcagaatcc
    13021 ggagagattg taattgatgg ccaacgtttg actgaggaaa atgtttggaa tatacgtcgt
    13081 caaatcggta tggtttttca aaatccagac aatcaatttg ttggagcgac tgttgaagat
    13141 gatgttgctt ttggtttgga aaatcaggga ctttctcgtc aagaaatgaa aaagagagtg
    13201 gaagaagctc tggatttagt tggcatgttg gactttaaaa agagagagcc agcgcgtcta
    13261 tcaggtggcc aaaagcaacg tgtggccatt gcaggtgttg tagccctaag accagctatt
    13321 ttaatcttag atgaagcaac gagtatgttg gatcctgagg ggcgtagaga acttattggg
    13381 acagtaaaag gaattcgaaa agactatgat atgacggtca tttctattac ccatgatttg
    13441 gaagaagtcg ccatgagtga tcgcgtattg gtcatgaaaa aaggggaaat tgaatcaact
    13501 agtagtccaa gggagctttt ctctcgaaat gatttagatc aaattggatt agacgatcct
    13561 tttgctaatc aattaaaaaa atctttgagc cagaatggct atgatttacc tgaaaattat
    13621 ttgacagaaa gtgagctaga ggataagcta tgggaattgc tctagaaaat gtgaatttta
    13681 catatcaaga aggtactccc ttagcttcag cagctttgtc ggatgtttct ttgacgattg
    13741 aagatggctc ttatacagct ttaattgggc acacaggtag tggtaaatca actattttac
    13801 aactcttaaa tggtttattg gtgccaagtc aagggagtgt gagggttttt gataccttaa
    13861 tcacctcgac ttctaaaaat aaagatattc gccaaattag aaaacaggtt ggcttggtat
    13921 ttcagtttgc tgaaaatcag atttttgaag aaacggtttt gaaggacgtt gcttttggac
    13981 cgcaaaattt tggagtttct gaagaagatg ctgtgaagac tgcgcgtgag aaactggctc
    14041 tggttggaat tgatgaatca ctttttgatc gtagtccgtt tgagctgtca gggggacaaa
    14101 tgagacgtgt tgccattgca ggcatacttg ccatggagcc agctatatta gtcttagatg
    14161 agccaacagc tggtctagat cctctaggga gaaaagagtt gatgaccctg ttcaaaaaac
    14221 tccaccagtc agggatgacc atcgtcttgg taacgcattt gatggatgat gttgctgaat
    14281 atgcgaatca agtctatgta atggaaaagg gacgtttagt aaaggggggc aaaccaagtg
    14341 atgtctttca agacgttgtt tttatggaag aagttcagtt gggagtacct aaaattacgg
    14401 ccttttgtaa acgattggct gatagaggcg tgtcatttaa acgattaccg attaagatag
    14461 aggagttcaa ggagtcgcta aatggatagt atgattttag ggcgttatat cccaggggat
    14521 tcgattgttc accgattgga tccacgtagc aaattgcttg ctatgatgct actgattttg
    14581 attgtgtttt gggctaataa ccccttgacg aatctgattc tttttatagc gacagggata
    14641 tttattgcct tgtcaggagt atctctttca ttttttattc agggcttgaa gtctatgttt
    14701 ttcttgattg ccttcacaac tatttttcaa ctatttttca tttctaatgg gaatgtttta
    14761 tttgagtttt cgtttgtgag aatcacggat tatgctttgc aacaagctgg gattattttt
    14821 tgtcgctttg tattgattat tttcttttca actttgttaa ccttaacaac catgccttta
    14881 agtttggcat cagctgtcga agctttatta gcacctttaa agcgtgtgaa agttccagtt
    14941 catgaaattg gattgatgct gtctatgagt ttgcgttttg tcccaacctt gatggatgat
    15001 acgactcgga ttatgaatgc acagaaagct cgtggagtgg attttggaga aggaagtatc
    15061 gttcaaaaag taaaggcgat gattcccatt ttgattcctc tttttgcgac aagtttaaaa
    15121 cgtgcagatt ccttggctat cgctatggaa gcgcgtggct atcagggtgg aaaaggcaga
    15181 agtcaatacc gacaattgaa atggactcta aaggatacgc tgaccattct tgttattctc
    15241 gtacttggtt gttgtttatt tttcttaaaa tcttagtagc tttcaggaat tgataaaaag
    15301 ttactgtaac agtttttgat ataaaggtag ggatatgaac cgttttaaaa aatcaaaata
    15361 tgtcattatt gtttttgtca ctgttctgct tgtgtcagct ctcttagcga cgacttattc
    15421 aagtacaatt gtgacaaaat taggagatgg aatctcattg gttgatagag ttgtacaaaa
    15481 accttttcag tggtttgatt ctgtcaaatc agatttggct catttgacac gaacatataa
    15541 tgaaaatgaa agtttgaaga aacagcttta ccaattagaa gttaaatcaa atgaggtgga
    15601 aagtttaaag acagaaaatg aacaactgcg ccaattgctt gatatgaagt ctaaattgca
    15661 agccacaaag actttagcag cagatgttat tatgcgttct ccggtatctt ggaagcagga
    15721 gttgacctta gatgcaggta gatcaaaagg tgcttctgag aacatgttag ctattgcaaa
    15781 tggtggcttg attgggagta tttcaaaagt agaggagaac tctactatag tcaaccttct
    15841 gacaaatacg gaaaatgctg ataagatttc tgttaaaatt caacatggct ctactacaat
    15901 ttatggaatt attattggct atgacaagga aaatgacgtt cttaaaatta gccaattaaa
    15961 tagtaatagc gatattagtg cgggagataa ggtgactact ggtggattag gaaactttaa
    16021 cgttgctgat attcctgttg gtgaagtggt tgccacaacg catagtacag actatttgac
    16081 acgagaagta actgttaaat tgagtgcaga tactcataat gtagatgtga tagaattagt
    16141 ggggaattca taatgagaca gttgaagcga gttggagtat ttttattgct tcctttcttt
    16201 gttctaattg acgcccatat tagccagctt ctgggctcat ttttccccca tgtacatttg
    16261 gctagtcatt ttctttttct atttctctta tttgagacga tagaagtatc agagtatctc
    16321 tacctagtct attgttttgt tataggcttg gtttatgatg tttacttttt ccatctaata
    16381 gggattacaa ctctcttatt tatcttattg ggagccttcc ttcataaatt gaatagtgtt
    16441 attttgttga atcgttggac aagaatgcta gctatgattg tgctgacatt cctgtttgaa
    16501 atgggtagtt atcttttggc ttttatggta gggttgacag tagatagcat gtcgattttt
    16561 atagtctata gcttggtacc gacgatgatt ttaaattttt tatggattac tgtttttcaa
    16621 tttatttttg aaaaatatta tctataagaa cgacatataa atgtaacaaa ggcgtaatat
    16681 ttattaggcc tttttttggt atactagtat tgtctttaaa agaaggagta tctacgtaat
    16741 atgaagaaaa aaatcttagc gtcactttta ttaagtacag taatggtttc tcaagtagct
    16801 gttttaacaa ctgcgcatgc agaaacgact gatgacaaaa ttgctgctca agataataaa
    16861 attagtaact taacagcaca acaacaagaa gcccaaaaac aagttgacca aattcaggag
    16921 caagtatcag ctattcaagc tgagcagtct aacttgcaag ctgaaaatga tagattacaa
    16981 gcagaatcta agaaactcga gggtgagatt acagaacttt ctaaaaacat tgtttctcgt
    17041 aaccaatcgt tggaaaaaca agctcgtagt gctcaaacaa atggagccgt aactagctat
    17101 atcaatacca ttgtaaactc aaaatcaatt acagaagcta tttcacgtgt tgctgcaatg
    17161 agtgaaatcg tatctgcaaa caacaaaatg ttagaacaac aaaaggcaga taaaaaagct
    17221 atttctgaaa aacaagtagc aaataatgat gctatcaata ctgtaattgc taatcaacaa
    17281 aaattggctg atgatgctca agcattgact acgaaacagg cagaactaaa agctgctgaa
    17341 ttaagtcttg ctgctgagaa agcgacagct gaaggggaaa aagcaagtct attagagcaa
    17401 aaagcagcag ctgaggcaga ggctcgtgca gctgcggtag cagaagcagc ttataaagaa
    17461 aaacgagcta gccaacaaca atcagtactt gcttcagcaa acactaactt aacagctcaa
    17521 gtgcaagcag tatctgaatc tgcagcagca cctgtccgtg caaaagttcg tccaacatac
    17581 agtacaaacg cttcaagtta tccaattgga gaatgtacat ggggagtaaa aacattggca
    17641 ccttgggctg gagactactg gggtaatgga gcacagtggg ctacaagtgc agcagcagca
    17701 ggtttccgta caggttcaac acctcaagtt ggagcaattg catgttggaa tgatggtgga
    17761 tatggtcacg tagcggttgt tacagctgtt gaatcaacaa cacgtatcca agtatcagaa
    17821 tcaaattatg caggtaatcg tacaattgga aatcaccgtg gatggttcaa tccaacaaca
    17881 acttctgaag gttttgttac atatatttat gcagattaat ttacagaggg actcgaatag
    17941 agccctcttt tcaggtttta ccgtgacaat ccctattaaa aattatatca aaatagcttg
    18001 aaaatattgg aaaagtatgg tagaatgaaa attgtcgtgt gaacgataat actcattctt
    18061 gatgaattgt gaagcagttg cccttgggtc gttttgcgag ttgaagtcaa gaagaggaaa
    18121 aaaacaaaaa ggagaaatac tcatggcagt aatttcaatg aaacaacttc ttgaggctgg
    18181 tgtacacttt ggtcaccaaa ctcgtcgctg gaatcctaag atggctaagt acatctttac
    18241 tgaacgtaac ggaatccacg ttatcgactt gcaacaaact gtaaaatacg ctgaccaagc
    18301 atacgacttc atgcgtgatg cagcagctaa cgatgcagtt gtattgttcg ttggtactaa
    18361 gaaacaagca gctgatgcag ttgctgaaga agcagtacgt tcaggtcaat acttcatcaa
    18421 ccaccgttgg ttgggtggaa ctcttacaaa ctggggaaca atccaaaaac gtatcgctcg
    18481 tttgaaagaa attaaacgta tggaagaaga tggaactttc gaagttcttc ctaagaaaga
    18541 agttgcactt cttaacaaac aacgtgcgcg tcttgaaaaa ttcttgggtg gtatcgaaga
    18601 tatgcctcgt atcccagatg tgatgtacgt agttgaccca cataaagagc aaatcgctgt
    18661 taaagaagct aaaaaattgg gaatcccagt tgtagcgatg gttgacacca atactgatcc
    18721 agatgatatc gatgtaatca tcccagctaa cgatgacgct atccgtgctg ttaaattgat
    18781 cacagctaaa ttggctgacg ctattatcga aggacgtcaa ggtgaggatg cagtagcagt
    18841 tgaagcagaa tttgcagctt cagaaactca agcagattca attgaagaaa tcgttgaagt
    18901 tgtagaaggt gacaacgctt aatttataca aatagtaatt acctaggagg gcggggctta
    18961 gcccggctct cctattttca aaaaatatag gagaattaaa atggcagaaa ttacagctaa
    19021 acttgtaaaa gagttgcgtg aaaaatctgg tgccggtgtt atggacgcta aaaaagcgct
    19081 tgtagaaaca gacggtgaca tcgaaaaagc gattgaattg cttcgtgaaa aaggtatggc
    19141 taaggcagct aagaaagctg accgtgttgc tgcagaaggt ttgactggtg tttatgttaa
    19201 cggtaatgtt gcagcagtta ttgaagtaaa cgctgaaact gacttcgttg caaaaaacgc
    19261 tcaattcgtt gaattggtaa atactacagc taaagtcatt gctgaaggaa aacctgctaa
    19321 caatgaagaa gctcttgctt tgataatgcc ttcaggtgaa actcttgaag ctgcatacgt
    19381 atctgcaaca gcaactatcg gagagaaaat ctcattccgt cgctttgcat tgattgaaaa
    19441 aacagacgca caacactttg gagcatacca acataacggt ggacgtatcg gtgttatttc
    19501 agttgttgaa ggtggagacg aagcacttgc taaacaattg tcaatgcaca tcgcagcgat
    19561 gaaaccaaca gttctttctt acaaagaatt ggatgagcaa ttcgttaaag atgagttggc
    19621 acaattgaat cacgttatcg accaagacaa cgaaagccgt gcaatggtta ataaaccagc
    19681 tcttccacac ttgaagtatg gatcaaaagc tcaattaact gatgatgtta ttgctcaagc
    19741 tgaagctgac atcaaagctg aattggctgc agaaggcaaa ccagaaaaaa tctgggacaa
    19801 aattattcca ggtaaaatgg atcgcttcat gcttgataac actaaagttg accaagctta
    19861 cacacttctt gcacaagttt acatcatgga tgacagcaag acagttgaag cataccttga
    19921 atcagttaac gcttcggtag ttgagtttgc tcgctttgaa gttggtgaag gtatcgagaa
    19981 agctgcaaac gacttcgaag ctgaagttgc agctacaatg gcagcagcct tgaataacta
    20041 ataatagaaa ggaagcaatt tgcttccttt tttgtatagg gcttatattt ttcctgaaat
    20101 tgtttttccc ccagtctcac tcgattagaa taattaaaac aaaaagccct ataataaggg
    20161 ctaagtgcat ttaggagact atacttcaaa ttcatagtaa gcgcgtcata acaaggtatc
    20221 tatcctaatt ccccaacttc cagtatacta gataaaaaat aattatcgga ggaaaggtat
    20281 tgtactatga tgattcaact aagtgattta ggtcaagttc acattgtttg tggcaagaca
    20341 gatatgaggc agggaataga ctcattagcc tatgtagtta aaacccactt tgaattggat
    20401 tctttctccg gtcaagtctt tctcttttgt ggtggacgta aagaccgctt taaagtcctt
    20461 tactgggatg gtcaaggatt ttggctacta tataaacgct ttgagaacgg aaaactgact
    20521 tggctaagta cagaaaagga tgtcaaagct ctcacatctg aacaagtaga ctggcttatg
    20581 aagggctttt ctatcactcc ccaaatatag tggtttgaaa ctagaatagt acacctctgc
    20641 ttctaaaaca ttgttagaaa tcgatttgac tgtcctgttc ttatttcatt ttactataaa
    20701 ttcatcagaa agtcgtgatt tctattgaaa tgaggacttt ctttttatac tcatctgttt
    20761 tcacaaagca ttctagtcca tctccgatta acgatggact ttatcacctc cttctccagt
    20821 ccttgtataa catcttggag ttgattcatg acatcttcca aaatttgaaa ggctttattc
    20881 ttaaatccac gtttacgaat ctctttccac acttgttcaa tggggttcat ctctggtgtg
    20941 tatggaggaa taaatgcaaa gccaatatta gtcggaatct ttaaggtact tgatttatgc
    21001 catatagcat tgtccataac gagtaaaaga taatcatctg gataagcttg tgaaatctcc
    21061 tattcctaaa gcccctttag cgcataactt tggctcagct tctattatcg ctcacaccat
    21121 ccatcagaag tttaatctga aggtacccaa ttatcgccaa gaagaagatt gggctaggat
    21181 gggtttacca atcacacgta aggaaatctc taatcggcat atcaagacga gtcaatacta
    21241 tttggagccc ctttataacc tcttgcgaga gagactattg actcagccct tacttcatgc
    21301 ggatgaaact tcttataggg tgctagagag tgatagtcag ctgacttact attggacttt
    21361 tttgtctggg aaagctgaga aacaagggat tacgctttac catcatgtcc taatcgattt
    21421 gttcatatct tatttcaatc cattataaat agtgagaaat atctatccta tcttctagaa
    21481 tgtcttccaa acgtggaaac tctcgtaaac aaagaggttt tagaggccta tttaccatgg
    21541 actaaagttg tacaagaaaa gtgcaaataa gaaatctcca gattaggaac tatccgtgag
    21601 ttctctagtc tggagatttt tcaatagact tcgttattgg acggttacaa ttcataaagt
    21661 gctgtagaga gataacgttc accgttatct ggtgctaggg caaggacttt tttacctgta
    21721 cctaattttt tggcaacctc gatggctccg tagatagctg cagctgagga aatccctaca
    21781 aggaagcctt cttttccacc aatttcacgt ccgagtgcaa gagcgtcatc tgatgttaca
    21841 cgaacgatac catcataggc tttagtatca agtgtatcag gaataaatcc agctgagata
    21901 ccttgaattt tgtgaggacc aggtttttca ccagatagaa tagcagattc atctgcttct
    21961 actgcaaaaa cttgaatgtt agaattttct gatttgagtg catgagaaac accagaaatc
    22021 gttccaccag tacctactcc agcaacaaag gcatctaatc catctttacc gaaagcagct
    22081 agtatctcag ctcctgttgt tctttcgtgt acttctggat tagctggatt gtcaaattga
    22141 agaggaagga aaccatcacg ttcagcagcg atttcttgag ccttagcaat agcacctttc
    22201 attccctcgc taccaggagt taggacgagt tcagcaccat aagcttggat aattttacgt
    22261 cgttctacac tcatagtttc aggcataacg atgacgactt tatacccttt agcagcacct
    22321 acccatgaaa gtccaatacc ggtgtttcca cttgttgctt caacaatagt agaaccaagt
    22381 ttcagaatac catcttgttc agctttttca atcatgctaa gggcaatacg gtcttttaca
    22441 gatgaaccag gattaaatgc ttcaagcttt atatagacgt ctgcagcacc ttctggcacg
    22501 atgttgttaa gtttaacaat cggtgtttga ccgattaatt cagtaatgtt gttataaata
    22561 gacatatgaa tacctctttg tataagatat ctttagtata acgctatcca taccatttgt
    22621 aaaatataga aatcctatcg aagcgatagg atttctatat atcatagatc aaagtcatta
    22681 attttcaagt gattgcgttc agttaattct agtaaatagg tgtgaaggaa aacgatatca
    22741 ggtttcgttt gaattgcttc attttctagt atattttggt acgcatcttt ttattttgct
    22801 cgctaaagta gttgtgagaa tgtcaacgaa acgctgtatt attcattgtt tacactaagt
    22861 ttacaggaac ttcaacctct cgtaaacctt ggtcagttaa agtgactttt ccattaaaaa
    22921 actccacaag tgcagcttta atagtttctt tttcttcttt atcaacataa atcatcgtat
    22981 cgacttgatc tgtaaagttt gtatccagct ccatgagatc atgttcttta aggaagttac
    23041 tgtactcttg gtactgagca taagacattt gaatagcaat gccagcctgt tcttttattt
    23101 caataatacc aatttctttg acagctaagg cgacactgct ggcgtaagca cgaattagtc
    23161 ctccagcgcc tagtttaata ccaccaaagt agcgtgtcac gaccacacag acattggtga
    23221 gattgtgatt ttctagtacc ccaagcatgg gaacaccagc agtaccacta ggctcaccat
    23281 catcacttgt acgtttaatt tcactacgtt ctccaataat aaaggcagag cagttatgtg
    23341 tcgctttgta gtgttctttt ttgatggcag taatgaagtc acgagcctct tcttcgctat
    23401 aaacacgctt ggcatggcag ataaagcgag attttttgat ttcttcttgg acttggccgt
    23461 cctctttaat tgtcctaaat tccatgattt aattgtacta aaaaatcatc taaagtgcta
    23521 gtttttacga ataaagaagt atgaaagtaa atttagatta tctcggtcgt ttatttactg
    23581 agaatgaatt aacagaagaa gaacgtcagt tggcggagaa acttccagca atgagaaagg
    23641 agaaggggaa acttttctgt caacgttgta atagtactat tctagaagaa tggtatttgc
    23701 ccatcggtgc ttactattgt cgagagtgct tgctgatgaa gcgagtcaga agtgatcaaa
    23761 ctttatacta ttttccgcag gaggattttc cgaagcaaga tgttctcaaa tggcgcggcc
    23821 aattaactcc ttttcaagag aaggtgtcag agggactgct tcaagcagta gacaagcaaa
    23881 agccaacctt agttcatgcg gtaacaggag ctggaaagac agaaatgatt tatcaagtag
    23941 tggctaaagt gatcaatgcg ggtggtgcag tgtgtttggc tagtcctcgc atagatgttt
    24001 gtttggagct gtacaagcgc ctgcaacagg atttttcttg cgggatagct ttgctacatg
    24061 gagaatcgga accttatttt cgaacaccac tagttgttgc aacaacccat cagttattga
    24121 agttttatca agcttttgat ttgctgatag tggatgaagt agatgctttt ccttatgttg
    24181 ataatcccac gctttaccat gctgtcaaga atagtgtaaa ggagaatgga ttgagaatct
    24241 ttttaacagc gacttcgacc aatgagttag ataaaaaggt ccgtttagga gaactaaaaa
    24301 gactgaattt accgagacgg tttcatggaa atccgttgat tattccaaaa ccaatttggt
    24361 tatcggattt taatcgctac ttagacaaga atcgtttgtc accaaagtta aagtcctata
    24421 ttgagaagca gagaaagaca gcttatccgt tactcatttt tgcttcagaa attaagaaag
    24481 gggagcagtt agaagaaatc ttacaggagc aatttccaaa tgagaaaatt ggctttgtat
    24541 cttctgtaac agaggatcga ttagagcaag tacaagcttt tcgagatgga gaactgacaa
    24601 tacttatcag tacgacaatc ttggagcgtg gagttacctt cccttgtgtg gatgttttcg
    24661 tagtagaagc caatcatcgt ttgtttacca agtctagttt gattcagatt ggtggacgag
    24721 ttggacgaag catggataga ccgacaggag atttgctttt cttccatgat gggttaaatg
    24781 cttcaatcaa gaaggcgatt aaggaaattc agatgatgaa taaggaggct ggtctatgaa
    24841 gtgcttgtta tgtgggcaga ctatgaagac tgttttaact tttagtagtc tcttacttct
    24901 gaggaatgat gactcttgtc tttgttcaga ctgtgattct acttttgaaa gaattgggga
    24961 agagaactgt ccaaattgta tgaaaacaga gttgtcaaca aagtgtcaag attgtcaatt
    25021 ttggtgtaaa gaaggagttg gagtcagtca tagagcgatt tttacttaca atcaagctat
    25081 gaaggatttt ttcagtcggt ataagtttga tggagacttc ctgttaagaa aagttttcgc
    25141 ttcattttta agtgaggagt tgaaaaagta caaagagtat caatttgttg taattcccct
    25201 aagtcctgat agatatgcta atagaggatt taatcaggtt gagggcttgg tagaggcagc
    25261 aggctttgag tatctggatt tattagagaa aagagaagag agagccagtt cttctaaaaa
    25321 tcgttcagag cgcttgggga cagaacttcc tttctttatt aaaagtggag tcactattcc
    25381 taaaaaaatc ctacttatag atgatatcta tactacagga gcaactataa atcgtgttaa
    25441 gaaactgttg gaagaagctg gtgctaagga tgtaaaaaca ttttcccttg taagatgagg
    25501 aaaaaatttg caaaaataga atgaaagcgt tataataaaa tcataaaaac aaaaatgttt
    25561 agaaagaagg tactcatatg attaaatata gtatccgtgg tgaaaaccta gaagtaacag
    25621 aagcaattcg tgattatgta gtttctaaac tcgaaaagat cgaaaagtac ttccaaccag
    25681 aacaagagtt ggatgcccga attaacttaa aagtttatcg tgaaaaaacg gctaaagtgg
    25741 aagtaacgat tccgcttgga tctattactc tccgcgcaga agatgtatct caagatatgt
    25801 atggttcaat tgaccttgta actgataaaa ttgaacgtca gattcgtaaa aataaaacaa
    25861 aaatcgagcg taaaaataaa aataaggtag caactggtca attatttaca gatgctttgg
    25921 tggaagattc aaatgttgtc cagtctaaag ttgttcgttc aaaacaaatt gatttaaaac
    25981 caatggattt ggaagaagca attctacaaa tggatttatt ggggcatgat ttctttatct
    26041 atgtggatgt tgaagatcag acaaccaatg tgatttatcg tcgtgaggat ggcgaaattg
    26101 gtttgttaga ggttaaagaa tcttaatttc aatatgtgta aaggtaggtt tactgaattg
    26161 taaactacct ttttcttata attgatagaa ttactgatta cacttttaaa aagtcgcttt
    26221 ttgaggggta ttatggtata atgggtgcca agaggttttg aatgaaaaaa ttttatgtaa
    26281 gtccaatttt tcctattcta gtaggattga ttgcgtttgg agtcttatcc actttcatta
    26341 tttttgttaa taataatctg ttgacggttt taattttgtt tctttttgta ggaggctatg
    26401 tttttttatt taagaaactg agagtgcatt atacaaggag tgatgtagaa cagatacagt
    26461 atgtaaacca ccaagcggaa gaaagtttga catctctatt ggaacaaatg cctgtaggtg
    26521 ttatgaaatt gaatttatct tctggagagg ttgagtggtt taatccctat gctgaattga
    26581 ttttgaccaa ggaagatggt gattttgatt tagaagctgt tcaaacgatt atcaaggctt
    26641 cagtaggaaa tccgtctact tatgccaagc ttggtgagaa gcgttatgct gttcatatgg
    26701 atgcttcttc cggtgttttg tattttgtag atgtatccag ggaacaagcc ataacagatg
    26761 aattggtaac aagtcgacca gtgattggga ttgtctctgt ggataattat gatgatttgg
    26821 aggatgcaac ttctgagtca gatattagtc aaatcaatag ttttgtagct aattttatat
    26881 cagagttttc agaaaaatac atgatgtttt ctcgtcgggt aagtatggat cgattttatc
    26941 tatttactga ctacacggtg cttgagggct tgatgaatga taaattttct gttattgatg
    27001 ctttcagaga agagtcgaaa cagagacagt tgcccttgac cttaagtatg ggattttctt
    27061 atggcgatgg aaatcatgat gagataggga aagttgcttt gctcaatttg aacttggctg
    27121 aagtacgtgg tggcgaccag gtggttgtta aggaaaacga cgaaacgaaa aatccagttt
    27181 attttggtgg tgggtctgct gcttcaatca agcgtacacg gactcgtacg cgcgctatga
    27241 tgacagctat ttcagataag attcggagtg tagatcatgt ttttgtagtc ggtcacaaaa
    27301 atttagacat ggatgctttg ggctctgctg taggtatgca gttgttcgcc agcaatgtga
    27361 ttgaaaatag ctatgctctt tatgatgaag aacaaatgtc tccagatatt gaacgagctg
    27421 tttcattcat agaaaaagaa ggagttacga agttgttgtc tgttaaggat gcaatgggga
    27481 tggtgaccaa tcgttctttg ttgattcttg tagaccattc aaagacagcc ttaacattat
    27541 caaaagaatt ttatgattta tttacccaaa ccattgttat tgaccaccat agaagggatc
    27601 aggattttcc agataatgcg gttattactt atatcgaaag tggtgcaagt agtgccagtg
    27661 agttggtaac ggaattgatt cagttccaga attctaagaa aaatcgtttg agtcgtatgc
    27721 aagcaagtgt cttgatggct ggtatgatgt tggatactaa aaatttcacc tcgcgagtaa
    27781 ctagtcggac atttgatgtt gctagctatc tcagaacgcg cggaagtgat agtattgcta
    27841 tccaggaaat cgctgcgaca gattttgaag aatatcgtga ggtcaatgaa cttattttac
    27901 aggggcgtaa attaggttca gatgtactaa tagcagaggc taaggacacg aaatgctatg
    27961 atacagttgt tattagtaag gcagcagatg ccatgttagc catgtcaggt attgaagcga
    28021 gttttgttct tgcgaagaat acacaaggat ttatctctat ctcagctcga agtcgtagta
    28081 aactgaatgt acaacggatt atggaagagt taggcggtgg aggccacttt aatttggcag
    28141 cagctcaaat taaagatgta accttgtcag aagcaggtga aaaactgaca gaaattgtat
    28201 taaatgaaat aaaggaaaag gagaaagaag aatgaaagta atctttttag cagatgttaa
    28261 aggaaaaggt aaaaaaggcg aaattaagga agtaccaaca gggtatgcgc aaaactttct
    28321 tatcaaaaag aatctagcca aagaagcgac tgctcaagct gtaggtgaac ttcgtggtaa
    28381 acaaaaatcg gaagaaaaag ctcacgctga gatgattgca gaaggaaaag caattaaagc
    28441 acaacttgaa gcagaagaaa ctgttgtaga atttgttgaa aaagttggtc cagatggtcg
    28501 tacctttggt tctattacca ataagaagat tgcagaagaa ttgcaaaagc aatttggaat
    28561 taagattgat aaacgtcata ttcaagtaca agctccgatt cgagcggttg gtttgattga
    28621 tgtgccagtg aaaatctatc aagatatcac aagtgtaatc aatcttcgtg tgaaagaagg
    28681 ataagtttac accttcttga caagattgta aaaggaagag aagtctgatg gcagaagtag
    28741 aagagttacg agtacaacct caagatatct tagctgagca atccgtttta ggggctatct
    28801 ttattgatga gagtaaactt gtttttgtgc gagaatacat tgagtctcgg gactttttta
    28861 agtatgccca tcgtttgatt ttccaagcca tggtcgattt atccgatcgt ggtgatgcca
    28921 tagatgcaac aacggttcgt actatccttg ataatcaagg tgatttacag aatattggtg
    28981 gcttgtctta cttggttgag attgtcaatt ctgtgccaac ttctgctaat gcggagtatt
    29041 atgctaagat tgttgcagaa aaagcaatgc tacgtcgttt aattgccaag ttgacagagt
    29101 ctgtcaacca agcttacgaa gcgtcacaac cagctgatga aattattgct caggcagaaa
    29161 aagggctgat tgatgtcagt gaaaatgcaa atcgaagcgg gtttaagaac attcgagatg
    29221 tgttgaatct caactttgga aatctggaag ctcgctcgca acaaacgacc gatattacag
    29281 gtattgcgac aggttatcgt gatttggatc atatgacaac aggacttcat gaggaggagt
    29341 tgattatctt agcagctcgt ccagcagttg gtaagacagc atttgccttg aatatcgctc
    29401 agaatattgg gactaagttg gacaaaacgg ttgctatttt ttcactcgaa atgggtgcgg
    29461 aaagcttggt agaccgtatg ttagctgcag aaggcttggt ggagtcacat tctatccgta
    29521 cagggcaatt gacagatgag gagtggcaaa aatatactat tgctcagggt aatctagcta
    29581 acgccagtat ctatatcgat gatacgccag gtattcggat tacagagatt cgttctcgtt
    29641 ctcgtaaatt ggctcaagaa actggaaatc ttggtttgat tttgatagac tatttgcaac
    29701 ttatcacggg aactggtcga gaaaatcgtc aacaagaagt ttctgaaatt tctcgtcagt
    29761 tgaaaatact agccaaggaa ttgaaggttc cagtaatcgc tctgagtcag ctttctcgtg
    29821 gtgtagaaca acgtcaggac aagagaccgg tcttgtctga tattcgtgaa tctgggtcta
    29881 ttgagcagga cgctgatatc gtagcttttc tctatcgcga tgactactat gaacgtggtg
    29941 gtgaagaaga ggagggtatc ccaaataata aggtggaagt tattatcgag aaaaaccgta
    30001 gtggagctcg tggaacagtg gaattgattt tccaaaaaga atacaataaa ttttcaagta
    30061 tctcaaagag ggaggcataa gatgtcagat gcatttacag atgtagccaa gatgaaaaaa
    30121 atcaaagaag aaattaaggc acatgaggga caagtcgtag aaatgacttt ggagaatggt
    30181 cgtaagcgcc aaaaaaatag attgggtaag ctaattgaag tttatccatc cctatttatt
    30241 gtggagtttg gggatgtgga aggagataaa caagttaatg tttacgttga atcctttact
    30301 tactcagata ttcttacaga aaagaatttg attcattatc ttgactaaag tgagaaattt
    30361 tctcactttt tcttttttct ccgaataatt taggtgaagg caatcatcgc tttatattat
    30421 tttttaagga ggaagaatga aaattttacc gtttatagca agaggaacaa gttattactt
    30481 gaagatgtca gttaaaaagc ttgttccttt tttagtagta ggattgatgc tagcagctgg
    30541 tgatagtgtc tatgcctatt ccagaggaaa tggatcgatt gcgcgtgggg atgattatcc
    30601 tgcttattat aaaaatggga gccaggagat tgatcagtgg cgcatgtatt ctcgtcaatg
    30661 tacttctttt gtagcctttc gtttgagtaa tgtcaatggt tttgaaattc cggcagctta
    30721 tggaaatgcg aatgaatggg gacatcgtgc tcgtcgggaa ggttatcgtg tagataatac
    30781 accgacgatt ggttccatta cttggtctac tgcaggaact tatggtcatg ttgcctgggt
    30841 gtcaaatgta atgggagatc agattgagat tgaggaatat aactatggtt atacagaatc
    30901 ctataataaa cgaattataa aagcaaacac gatgacagga tttattcatt ttaaagattt
    30961 ggatggtggc agtgttggga atagtcaatc ctcaacttca acaggcggaa ctcattattt
    31021 taagaccaag tctgctatta aaactgaacc cctagttagt gcaactgtga ttgattacta
    31081 ttatcctggg gagaaggttc attatgatca gatacttgaa aaagacggct ataagtggtt
    31141 gagttatact gcctataatg gaagttatcg ttatgttcaa ttggaggctg tgaataaaaa
    31201 tcctctaggt aattctgttc tttcttcaac aggtggaact cattatttta agaccaagtc
    31261 tgctatcaaa actgaacccc tagttagcgg aactgtgatt gattactatt atcctgggga
    31321 gaaggttcat tatgatcaga tacttgaaaa agacggctac aagtggttga gttatactgc
    31381 ctataatgga agtcgtcgct atatacagct agagggagtg acttcttcac aaaattatca
    31441 gaatcaatca ggaaatatct ctagctatgg atccaataat agttcaactg tcggttggaa
    31501 gaaaataaat ggtagttggt atcatttcaa atcaaatggt tctaaatcaa caggatggct
    31561 gaaagacggt tctagctggt attatttgaa attatctggt gaaatgcaga caggatggtt
    31621 aaaggagaat ggctcgtggt attatctggg tagttcaggg gcaatgaaaa caggctggta
    31681 ccaggtctct ggtaagtggt attattctta ctcttcaggc gccttagctg ttaatacgac
    31741 ggtggatggc tacagagtaa acagtgatgg agaacgagta tagaaaattg gagtaggaga
    31801 aatttcctgc tcttttctgt aagcagtttc cttgacattt ttcttatttt gcgctatcat
    31861 atatacatat aatatatggg agtctgtgta cagtctgaga ggaagtgtta aacttcgacc
    31921 gcacctgatc tgggtaatgc cagcggaggg aacgatactt agtctaattt tgcacctttt
    31981 ccatgtatgg taaaggtttt tctttttttt aaaaggaaaa cgagaagagg aggttcttat
    32041 gaaagcaagc attgccttgc aagttttacc cttagcacag gggattgatc ggatagctgt
    32101 tattgatcag gtcattgctt atctgcaaac tcaagaagtg acgatggtag tgacaccatt
    32161 tgaaacggtc ttggaagggg agtttgatga gcttatgcgc attctaaaag aagcgctgga
    32221 agtggcaggg caggaggcag acaatgtctt tgccaatgtc aaaataaatg taggagagat
    32281 tttaagtatt gatgagaaac ttgaaaagta tactgagacg acacattagt ctattgggct
    32341 ttctcggagt attgtcaatc tggcagttag caggttttct taaacttctc cccaagttta
    32401 tcctgccgac acctcttgaa attctccagc cctttgttcg tgacagagaa tttctctggc
    32461 accatagctg ggcgaccttg agagtggctt tactggggct gattttggga gttttgattg
    32521 cctgtcttat ggctgtgctc atggatagtt tgacttggtt caatgacctg atttacccta
    32581 tgatggtggt cattcagacc attccgacca ttgccatagc tcctatcctg gtcttgtggc
    32641 taggttatgg gattttgccc aagattgtct tgattatctt aacgacaacc tttcccatca
    32701 tcgtcagcat tttggacggt tttaggcatt gcgacaagga tatgctgact ttgtttagtc
    32761 tgatgcgggc caagccttgg caaatcctgt ggcattttaa aattccagtc agcctgccct
    32821 acttttatgc tggtctgagg gtcagtgtct cctacgcttt tatcacaaca gtggtatctg
    32881 agtggttggg aggctttgag gggcttggtg tttatatgat tcagtccaag aaattgtttc
    32941 agtatgatac catgttcgct attattattc tggtatcgat tatcagcctt ttgggtatga
    33001 agttggtcga tattagtgaa aaatatgtta ttaaatggaa acgttcgtag aattagaatg
    33061 tttctgaaaa agaaaagagg aaatcaaaat gaagaaaaca tggaaagtgt ttttaacgct
    33121 tgtaacagct cttgtagctg ttgtgcttgt ggcctgtggt caaggaactg cttctaaaga
    33181 caacaaagag gcagaactta agaaggttga ctttatccta gactggacac caaataccaa
    33241 ccacacaggg ctttatgttg ccaaggaaaa aggttatttc aaagaagctg gagtggatgt
    33301 tgatttgaaa ttgccaccag aagaaagttc ttctgacttg gttatcaacg gaaaggcacc
    33361 atttgcagtg tatttccaag actacatggc taagaaattg gaaaaaggag caggaatcac
    33421 tgccgttgca gctattgttg aacacaatac atcaggaatc atctctcgta aatctgataa
    33481 tgtaagcagt ccaaaagact tggttggtaa gaaatatggg acatggaatg acccaactga
    33541 acttgctatg ttgaaaacct tggtagaatc tcaaggtgga gactttgaga aggttgaaaa
    33601 agtaccaaat aacgactcaa actcaatcac accgattgcc aatggggtct ttgatactgc
    33661 ttggatttac tacggttggg atggcatcct tgctaaatct caaggtgtag atgctaactt
    33721 catgtacttg aaagactatg tcaaggagtt tgactactat tcaccagtta tcatcgcaaa
    33781 caacgactat ctgaaagata acaaagaaga agctcgcaaa gtcatccaag ccatcaaaaa
    33841 aggctaccaa tatgccatgg aacatccaga agaagctgca gatattctca tcaagaatgc
    33901 acctgaactc aaggaaaaac gtgactttgt catcgaatct caaaaatact tgtcaaaaga
    33961 atacgcaagc gacaaggaaa aatggggtca atttgacgca gctcgctgga atgctttcta
    34021 caaatgggat aaagaaaatg gtatccttaa agaagacttg acagacaaag gcttcaccaa
    34081 cgaatttgtg aaataatgac agaaattaga ctagagcacg tcagttatgc ctatggtcag
    34141 gagaggattt tagaggatat caacctacag gtgacttcag gcgaagtggt ttccatccta
    34201 ggcccaagtg gtgttggaaa gaccaccctc tttaatctaa tcgctgggat tttagaagtt
    34261 cagtcaggga gaattgtcct tgatggtgaa gaaaatccca aggggcgcgt gagttatatg
    34321 ttgcaaaagg atctgctctt ggagcacaag acggtgcttg gaaatatcat tctgcccctc
    34381 ttgattcaaa aggtggataa ggcagaagct atttcccgag cggataaaat tcttgcgacc
    34441 ttccagctga cagctgtaag agacaagtat cctcatgaac ttagcggtgg gatgcgccag
    34501 cgtgtagcct tactccggac ctaccttttt gggcacaagc tctttctctt agatgaggcc
    34561 tttagcgcct tggatgagat gacaaagatg gaactccacg cttggtatct tgagattcac
    34621 aaacagttgc agctaacaac tctgatcatc acgcatagta ttgaggaggc cctcaatctc
    34681 agcgaccgca tctatatctt gaaaaatcgc cctgggcaga ttgtttcaga aattaaacta
    34741 gattggtctg aagatgagga caaggaagtc caaaagattg cctacaaacg tcaaatcttg
    34801 gcagaattag gcttagataa gtagaaaaat agggagttgg tgaagattat cctttaccag
    34861 cgcccttttt cttttaaaaa tgagaaaatt tcggtataat agtcaaacaa ggtcaaggtt
    34921 taaagagaga ggtgggtttg ttatgagatt taaaaataca tcggatcata ttgaggccta
    34981 catcaaggcg attttagatc aatctggtat cgtggagttg caacggagtc agttggcaga
    35041 tacctttcag gttgttccta gtcagattaa ctacgtgatc aagacacgct ttacggaaag
    35101 tagaggctac ttggttgaaa gtaagcgtgg tggcggaggc tacattcgta taggacggat
    35161 tgagttttct agtcatcatg aaatgctccg ggatctgctt tactcgattg gtgagcgagt
    35221 cagtcaagaa atttatgagg atattctcca gcttttggtt gagcaggaat tgatgaccaa
    35281 gcaggagatg aatttgctag aatcagtagc tttggatcgc gttttaggag aagaagctcc
    35341 agttgttcga gcaaacatgc tacgtcaggt catacaagag gtagatagaa aagggaagta
    35401 agatgaacta ttcaaaagca ttgaatgaat gtatcgaaag tgcctacatg gttgctggac
    35461 attttggagc tcgttatcta gagtcgtggc acttgttgat tgccatgtct aatcacagtt
    35521 atagtgtagc aggggcaact ttaaatgatt atccgtatga gatggaccgt ttagaagagg
    35581 tggctttgga actgactgaa acggactata gccaggatga aacctttacg gaattgccgt
    35641 tctcccgtcg tttgcaggtt ctttttgatg aagcagagta tgtagcgtca gtggtccatg
    35701 ctaaggtact agggacagag cacgtcctct atgcgatttt gcatgatggc aatgccttgg
    35761 cgactcgtat cttggagagg gctggttttt cttatgaaga caagaaagat caggtcaaga
    35821 ttgctgccct tcgtcgaaat ttagaagaac gtgcaggctg gactcgtgaa gatctcaagg
    35881 ctttacgcca acgccatcgt acagtagctg acaagcaaaa ttctatggcc aatatgatgg
    35941 gcatgccgca gactcctagt ggtggtctcg aggactatac gcatgatttg acagagcaag
    36001 cgcgttctgg caagttagaa ccagtcatcg gtcgggacaa ggaaatctca cgtatgattc
    36061 aaatcttgag ccgtaagact aagaacaacc ctgtcttggt tggggatgct ggtgtcggga
    36121 aaacagctct ggcccttggt cttgcccagc gtattgctag tggtgacgtg cctgcggaaa
    36181 tggctaagat gcgcgtgtta gaacttgatt tgatgaatgt cgttgcaggg acacgcttcc
    36241 gtggtgactt tgaagaacgc atgaataata tcatcaagga tattgaagaa gatggccaag
    36301 tcatcctctt tatcgatgaa ctccacacca tcatgggttc tggtagcgga attgattcga
    36361 ctctggatgc ggccaatatc ttgaaaccag ccttggcgcg tggaactttg agaacggttg
    36421 gtgccaccac tcaggaagaa tatcaaaaac atatcgaaaa agatgcggct ctttctcgtc
    36481 gtttcgctaa agtgacgatt gaagaaccaa gtgtggcaga tagtatgact attttacaag
    36541 gtttgaaggc gacttatgag aaacatcacc gtgtacaaat cacagatgaa gcggttgaaa
    36601 cagcggttaa gatggctcat cgttatttaa ccagtcgtca cttgccagac tctgctatcg
    36661 acctcttgga cgaagcagca gcaacagtgc aaaataaggc aaagtatgta aaagcagacg
    36721 attcagattt gagtccagct gacaaggccc tgatggatgg caagtggaaa caggcagccc
    36781 agctaatcgc aaaagaagag gaagtacctg tctacaaaga tttggtgaca gagtctgata
    36841 ttttgaccac cttgagtcgc ttgtcaggaa tcccagttca aaaactgact cagactgacg
    36901 ctaagaaata tctaaatctt gaagcagaac tccataaacg ggttatcggt caagatcaag
    36961 ctgtttcaag tattagtcgt gcgattcgcc gtaatcagtc aggaattcgc agtcacaagc
    37021 gtccgatcgg ttcctttatg ttcctaggac ccacaggtgt cggtaagacc gagttggcca
    37081 aggctttggc agaagttctc tttgatgacg aatcagccct tatccgcttt gatatgagtg
    37141 agtatatgga gaaattcgca gccagccgtc taaatggagc tcctccaggc tatgtgggtt
    37201 acgaagaagg tggggagttg acagagaagg ttcgcaataa accctattcc gttctcctct
    37261 ttgatgaggt agagaaggct cacccagata tctttaatgt tctcttgcag gttctggatg
    37321 acggtgtctt gacagatagc aagggacgca aggtcgattt ttcaaatacc attatcatta
    37381 tgacatcgaa cctaggtgcg actgcccttc gtgatgataa gactgttggt tttggggcta
    37441 aggatattcg ttttgaccag gaaaatatgg aaaaacgcat gtttgaagaa ctgaaaaaag
    37501 cttatagacc ggaattcatc aaccgtattg atgagaaggt ggtcttccat agcctatcta
    37561 gtgaccatat gcaggaagtg gtgaagatta tggtcaagcc tttagtggca agtttggctg
    37621 aaaaaggcat tgacttgaaa ttacaagctt cagctctgaa attgttagca aatcaaggat
    37681 atgacccaga gatgggagct cgcccacttc gcagaaccct gcaaacagaa gtggaggaca
    37741 agttggcaga acttcttctt aagggagatt tagtggcagg cagcacactt aagattggtg
    37801 tcaaagcagg ccagttaaaa tttgatattg cataaaagaa taaaagtatc agcatctgac
    37861 cataagtcac agtggagtga aactcaatga aaatcaaaga acaaactagg cagctagccg
    37921 caggttgctc aaaacactgt tttgaggttg tagatagagc tgacgtggtt tggagagatt
    37981 ttcgaagagt ataagctgca agatgaatga ttttcttgta ttgacgttgt tgttgacaaa
    38041 aagtagcgga taaatgaaat ccattctatt atcatagatg ataggctggt aggaaatttt
    38101 caaatagcat acaggaaata gatgtatgga gttctggtag tagaaaggga gagagatgaa
    38161 cattttagtt gcagatgacg aggaaatgat tagagaagga attgcagcat ttctgacaga
    38221 agagggttat catgtcatta tggctaagga tggacaagag gtcttggaaa aatttcaaga
    38281 tctccctatc catctcatgg tattggattt aatgatgcct aggaagagtg gttttgaagt
    38341 gttaaaagaa atcaatcaaa agcacgatat tcctgtcatc gtcttgagtg ctctgggaga
    38401 tgaaactact cagtcacagg tatttgatct ctatgctgat gatcatgtga caaaaccttt
    38461 ttctttggta ctgcttgtca agcgtattaa ggcgcttatc agacgttact acgtcataga
    38521 ggatatttgg cgatatcagg atgtaacagt ggattttacc tcttacaaag cacattataa
    38581 aaatgaagaa attgatctca agccaaagga attactggta ctaaagtgtt tgattcagca
    38641 taaaaatcaa gttttaagta gagagcagat attggaagaa atttcaaaag atgtagctga
    38701 tttaccttgt gatagggtcg ttgatgtcta tattcgtact cttcgcaaaa aattagcttt
    38761 agattgtatc gtgactgtga aaaatgttgg gtataagatt agcttatgat aaaaaatcct
    38821 aaattattaa ccaagtcttt tttaagaagt tttgcaattc taggtggtgt tggtctagtc
    38881 attcatatag ctatttattt gacctttcct ttttattata ttcaactgga gggggaaaag
    38941 tttaatgaga gcgcaagagt gtttacggag tatttaaaga ctaagacatc tgatgaaatt
    39001 ccaagcttac tccagtctta ttcaaagtcc ttgaccatat ctgctcacct taaaagagat
    39061 attgtagata agcggctccc tcttgtgcat gacttggata ttaaagatgg aaagctatca
    39121 aattatatcg tgatgttaga tatgtctgtt agtacagcag atggtaaaca ggtaaccgtg
    39181 caatttgttc acggggtgga tgtctacaaa gaagcaaaga atattttgct tttgtatctc
    39241 ccatatacat ttttggttac aattgctttt tcctttgttt tttcttattt ttatactaaa
    39301 cgcttgctca atcctctttt ttacatttca gaagtgacta gtaaaatgca agatttggat
    39361 gacaatattc gttttgatga aagtaggaaa gatgaagttg gtgaagttgg tgaagttgga
    39421 aaacagatta atggtatgta tgagcacttg ttgaaggtta ttcatgagtt ggaaagtcgt
    39481 aatgagcaaa ttgtaaaatt gcaaaatcaa aaggtttcct ttgtccgcgg agcatcacat
    39541 gagttgaaaa cccctttagc cagtcttaga attatcctag agaatatgca gcataatatt
    39601 ggagattaca aagatcatcc aaaatatatt gcaaagagta taaataagat tgaccagatg
    39661 agccacttat tggaagaagt actggagtct tctaaattcc aagagtggac agagtgtcgt
    39721 gagaccttga ctgttaagcc agttttagta gatattttat cacgttatca agaattagct
    39781 cattcaatag gtgttacaat tgaaaatcaa ttgacagatg ctaccagggt cgtcatgagt
    39841 cttagggcat tggataaggt tttgacaaac ctgattagta atgcaattaa atattcagat
    39901 aaaaatgggc gcgtaatcat atccgagcaa gatggctatc tctctatcaa aaatacatgt
    39961 gcgcctctaa gtgaccaaga actagaacat ttatttgata tattctatca ttctcaaatc
    40021 gtgacagata aggatgaaag ttccggtttg ggtctttaca ttgtgaataa tattttagaa
    40081 agctatcaaa tggattatag ttttctccct tatgaacacg gtatggaatt taagattagc
    40141 ttgtagacag attagttttt tattaaagtt catatagggt taacataagt gtgttattct
    40201 ttgtgtagat aaaagaaagg atactaatat ggtattagcg attattttag taacattcct
    40261 tattcgattg atttttttaa agcgttcgat agagaatgag aaacgaatcc ttagcaatgg
    40321 cgggaaagaa tttggagttg agaatacaaa acgattaact atggctcata ttgtttttta
    40381 tctctcttgc ttggttgagg caatggtgca caagacaatt tttgatggca tgggcatggt
    40441 tggtttagtc ttgcttattt tttctatgct gatgttaatg ttggtgattc acttgttggg
    40501 agatatttgg acagtgaagc ttatgcttgt caataatcac aaatatgtag atcatatctt
    40561 gtttaggaca gtaaaacatc ctaattactt tttaaatatt cttcctgagt tgattggctt
    40621 gaccttgttg agtcatgctt atgtgacttt tgttttagtt tttccagttt atgcagttat
    40681 tttgtatcga cgaatagctg aagaggaaaa gctattacat gaagttataa tcccaaatgg
    40741 aagcataaag agataaatac aaaattcgat ttatatacag ttcatattga agtgatatag
    40801 taaggttaaa gaaaaaatat agaaggaaat aattatgttt gcatcaaaaa gcgaaagaaa
    40861 agtacattat tcaattcgta aatttagtat tggagtagct agtgtagtag ttgccagctt
    40921 gttcttagga ggagtagtcc atgcagaagg ggttagaagt gggaataact ccacggttac
    40981 atctagtggg caagatatat cgaagaagta tgctgatgaa gtcgagtcgc atctacaaag
    41041 tatattgaag gatgtcaata aaaatttgaa aaaagttcaa catacccaaa atgccgactt
    41101 caacaaaaag ttgagcaaaa ttaaaacgaa gtatttgtat gaattaaatg ttttagaaga
    41161 gaagtcggaa gctgagttga cgtcaaaaac aaaagaaaca aaagaagagt taaccgcagc
    41221 ttttgagcag tttaaaaaag atacattatc aacagaacca gaaaaaaagg tagcagaagc
    41281 taagaagaag gttgaagaag ctaagaaaaa agccgaggat caaaaagaag aagatcgtcg
    41341 taactaccca accaatactt acaaaacgct tgaacttgaa attgctgagt ccgatgtgga
    41401 agttaaaaaa gcggagcttg aactagtaaa agaggaagct aaggaacctc gaaacgagga
    41461 aaaagttaag caagcaaaag cggaagttga gagtaaacaa gctgaggcta caaggttaga
    41521 aaaaatcaag acagatcgta aaaaagcaga agaagaagct aaacgaaaag cagcagaaga
    41581 agataaagtt aaagaaaaac cagctgaaca accacaacca gcgccggctc ctcaaccaga
    41641 aaaaccagct ccaaaaccag aaaaaccagc tccagctcca aaaccagaga atccagctga
    41701 acaaccaaaa gcagaaaaac cagctgatca acaagctgaa gaagactatg ctcgtagatc
    41761 agaagaagaa tataatcgct tgactcaaca gcaaccgcca aaaactgaaa aaccagcaca
    41821 accatctact ccaaaaacag gctggaaaca agaaaacggt atgtggtact tctacaatac
    41881 tgatggttca atggcgacag gatggctcca aaacaatggc tcatggtact acctaaacag
    41941 caatggcgct atggcgacag gatggctcca aaacaatggt tcatggtact atctaaacgc
    42001 taatggttca atggcaacag gatggctcca aaacaatggt tcatggtact acctcaacgc
    42061 taatggttca atggcgacag gatggctcca atacaatggt tcatggtact acctaaacgc
    42121 taatggtgat atggcgacag gatggctcca atacaatggc tcatggtact acctaaacgc
    42181 taatggtgat atggcgacag gatggctcca aaacaatggc tcatggtact acctaaacgc
    42241 taatggttca atggtgacag gatggctcca atacaatggt tcatggtact acctaaacgc
    42301 taacggttca atggcaacag
//
LOCUS       DAVDZK010000016        41997 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVDZK010000016 DAVDZK010000000
VERSION     DAVDZK010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41997
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.016"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            203..841
                     /locus_tag="VUX16_000989"
     CDS             203..841
                     /locus_tag="VUX16_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET8123973.1"
                     /translation="MLNKMKVSFLLGLGGLAVMSFVVMMGYTIGSQSVTHHMQKQIQT
                     EAHKLLTQEKEKEKASVLSDELVKEFLTQYYTKGKLGENNNRIKLYMTDSAYKEEVAR
                     QEDSINQVYKDYMLDYRFETAQIYVNTEANEALAEVSYQVVYVSDVSDKAQKSTQTET
                     KSLKLSYTKMSDKFLVKQVTVWNGKLENLKEVSDGADSSIPDIQGTTTSETN"
     gene            880..1968
                     /locus_tag="VUX16_000990"
     CDS             880..1968
                     /locus_tag="VUX16_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HET8123974.1"
                     /translation="MTRIEAVKQKAILEVAESLGYSFKRLSGQVYEHPEHDSFRIFAD
                     TNTFKWFSRDIQGDVIDFVQLITGVTFKEALSYLETGDFEQTKMVEETYQPFRYYLRE
                     EPFYQARIYLNDIRGLSDDTINAFGRQGLLAQAHYQTKIFQESVLVFKSYSHHGQLEG
                     ASLQGLVKNNERHDRDYLKKIMKGSHGYVGMSFDIGKPERLIFCESVIDMMSYYQLHQ
                     NQLSDVRLVSMEGLKLSVIAYQSLRLVAEEQGKLEFLDTVKPSRLTHYLHAIQETTTF
                     FQTHPSLITLAIDNDGAGRDFCQKLSEKSLPIETDLPPLQELETKADWNDVVKSQKDL
                     SLKDMIQSAKLQVIRSNPPPRKNTALEL"
     gene            2022..2255
                     /locus_tag="VUX16_000991"
     CDS             2022..2255
                     /locus_tag="VUX16_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123975.1"
                     /translation="MSVIERLAERVARQEEKVAKETEKLGTYREQLQAAMYSIFVKRQ
                     QSSHLTFDEALNQAFGKQENHSQVIENRNEETE"
     gene            2252..2647
                     /locus_tag="VUX16_000992"
     CDS             2252..2647
                     /locus_tag="VUX16_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HET8123976.1"
                     /translation="MTKDWTFDQSLDDNTPTSSTEERAKIAALFHKEEKEETGEVNYV
                     AAFEMEQQKAKEKSVSKPKVQEQSTPKEVPSSTITSDYKQHLANVMAQNNEDILQSQK
                     KIEELNQLIDDKNKQNKKLQAISEAIDDL"
     gene            2693..2980
                     /locus_tag="VUX16_000993"
     CDS             2693..2980
                     /locus_tag="VUX16_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123977.1"
                     /translation="MRLFKKQTHNQDSFKRLIHRLSGMSETDLHKVNQLLDVVFDATS
                     QTIHEETMTPKDMPKEPILDETITEAKNKLNTEQLEKRIEQFRQAKKPKSG"
     gene            3049..3525
                     /locus_tag="VUX16_000994"
     CDS             3049..3525
                     /locus_tag="VUX16_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8123978.1"
                     /translation="MIGENIKSLRRTHDLTQPEFAKIVGISRNSLSRYENGTSSVSTE
                     LIDRICQKFNVSYVDIVGEEKMLTPVEDYQLTLKIEVIKERGAAVLSQLYRYQDSQGI
                     AFDDETNPWILMSDDLSDLINTKIYLVDTFDEVERYNGYLDGIERMLELARHQVVA"
     gene            3525..4307
                     /locus_tag="VUX16_000995"
     CDS             3525..4307
                     /locus_tag="VUX16_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET8123979.1"
                     /translation="MALEAFRQDDFDLALKRTIRSLTRGKTVSTSPQAILLGGQSGAG
                     KTTIHRIKQKEFQGNIIIIDGDSYRSLHPNYLVLQEEYGKDSVDYTKFFAGKMVEHLV
                     DELSKDGYHLLIEGTLRTTEVPRKTAQLLKSRDYQVSLALIATKPELSYLSTLIRYEE
                     VYAENPSQARATSKEHHDGIVEHLVDNLRELETDKLFDQIQIYQRDKRCVYDSDTDDG
                     SVADVLQDCLFGKWSKVEEEMIKEAKEYLKRLSKSNNENILV"
     gene            4504..5067
                     /locus_tag="VUX16_000996"
     CDS             4504..5067
                     /locus_tag="VUX16_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123980.1"
                     /translation="MTESQNIGNFSNNNVQNMYVTNIEQRTLIPTVIFQLLKYVEGFH
                     SQNDEKFLLEQPAELKEKLQFNNSRRYIRLFKEGLSNYISLEKVLKDEFTDSQRVVEN
                     IKNIFMDHTPIDAEGNPIVGNGDECLKKMHDDIKERIARDPNFLSSQIDDLELDKFII
                     ALLQYGVIECQILLNPNNYMECNDVIT"
     gene            5054..5287
                     /locus_tag="VUX16_000997"
     CDS             5054..5287
                     /locus_tag="VUX16_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000925380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123981.1"
                     /translation="MLLLDKNAEPKKTIFYLSAIVHGLILKRIVNIENLYIELQKEIE
                     DELNYDFFILALDFLFLLDKIRVNNEGDIESVH"
     gene            5277..6995
                     /locus_tag="VUX16_000998"
     CDS             5277..6995
                     /locus_tag="VUX16_000998"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
                     /protein_id="HET8123982.1"
                     /translation="MFIKSLSIISKNTDVVLRKIEFKNGINFIVDSEKSYKHNKVGKT
                     TCLKLLDLSLGAKSKDAIFKDYETQSVNEQLRLFIENQKIYTDMVLIDDFNHPSKEVS
                     IKTELFNRGKRYINGEQTSYDEVNKYLNELLFENRSQKPSFRSAIKSFVRILMTKDNT
                     QFLKVLDNFSNISEYRAVYNYLFDISDLENDLEFGKLKQELKNIKSKENNYKKVNTVD
                     DVVKIKQINVAIEKEIDRLEKEINDLVDKKAFEKNRIHINDIRKKYEEISRQLSKIDF
                     DILQLQKYIKEAEEKSQRIVNQELANDFFQEISELLPSITKTFMDLVEFNSQLSRNKL
                     SYFNDRMQELIMEKEDKENLLTKLTEENSEFISLVEENKVDLYYDKLNQLDELKIKKV
                     KNESTITSLGNIEEQKNTLEKRLSKLEMIVKNNEAEYQKKMDIFNSYFKSVADRINKE
                     QPVLLYNPKTDEFPVSIGQLSEGTSTGTRKSLIAAYDIAYQLFAREINKATPKFIVHD
                     VLESIEGDDIRALVDEVESNQIQYISAILKEKLVSSGMSTEKQNEIIVLQLSMKDRLF
                     ERGNNC"
     gene            7329..7691
                     /locus_tag="VUX16_000999"
     CDS             7329..7691
                     /locus_tag="VUX16_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123983.1"
                     /translation="MRQDIKLIRKQFRITRQEDNQIKEMMREQQLESFSEFLRQNLLK
                     KESHEDVLIRWFTLWQSQKIEQISRDILQVTTLAEQSHQVTAEHLRIILTCVQELIAE
                     VNQASPLSQDFRDKYMGG"
     gene            7694..8059
                     /gene="mobC"
                     /locus_tag="VUX16_001000"
     CDS             7694..8059
                     /gene="mobC"
                     /locus_tag="VUX16_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HET8123984.1"
                     /translation="MENRYRTNLKKVFLTDQELAVLHDRIGQSRCKNFSAYARKVLLN
                     PNMTFLTIDTSNYEDLVFELRRIGNNINQIARTVNQNHILTPSDRELLVQGICQLIKE
                     VEKDFNIKCQQLKEFYGSH"
     gene            8046..9932
                     /locus_tag="VUX16_001001"
     CDS             8046..9932
                     /locus_tag="VUX16_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HET8123985.1"
                     /translation="MVVTKHFAVHSTKYRKSLIKYILNPEKTEQLKLISDFGMRNYLV
                     FPSYEEMVEMYEANLTNNDRLYDSRNDRQQIKQTKIHAHHLIQSFSPEDKLTPEEINR
                     IGYETIKELTGGNFRFIVTTHTDRNHVHNHILINSVDLNSDKKLKWDYVQERNLRMIS
                     DRLAKEAGATIIQPNRYSHEKFETYRKTNHKFELKQRLYFLLEHSNNFEEFLAKAPAI
                     NVEMDFSHKHARFLMTDREMKQVIRGKQLDKRQPYTEDYFREQFATRAIEQRLDFILP
                     RARDLSHLLEMAEQLNLTISPKKKHVTFTLTEKGRTISIENKKISTKHLYDVQFFEDY
                     FDQRESLTDPDLTNLVSDFEIYQEEQDKDKLPSEELLAAYKEFKEKRDQIQEFEVVLA
                     DHQIDKVVKDGLFIKMNYGVKKDGLVFIPNRNLDIHENEQGKSHHVFIRETAQFFIYN
                     KDSVDLNRYMRGRELICQLTHDSKHIPKRRRPTIASLKEKISEVNLLIELDINNQSYQ
                     EVKDELIKDIAQLDLTITNLQDKVAHLNKVAEILLNLNNSDPENRRLARYDYVKMNLT
                     AAINFEQVEQEISRSQQSLKDLIDKYEFKVRRLEKFVKNISSIYDYPFGGKTYTNNYQ
                     PDFE"
     gene            10339..10599
                     /locus_tag="VUX16_001002"
     CDS             10339..10599
                     /locus_tag="VUX16_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HET8123986.1"
                     /translation="MDNNFMSFPDRIGTNSSKWRIFETNPNMVSSSLADMDFEIPEFI
                     RSVFIDYMALDFMGYSYQSEKALEAILNWEKKNMGTILIKKN"
     gene            10554..10931
                     /locus_tag="VUX16_001003"
     CDS             10554..10931
                     /locus_tag="VUX16_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET8123987.1"
                     /translation="MGKKEHGYYFDKEKLILLDSVMTGVANAIQAFTNLGDAVLINDP
                     VYPSFKQIIENNGRKPVFSELEIKDGVYRFNFEKFEDCIITNKVKVFVLCNPHNPLGR
                     AWEIAELNKIGNICLKYNPDFIT"
     gene            11061..11330
                     /locus_tag="VUX16_001004"
     CDS             11061..11330
                     /locus_tag="VUX16_001004"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123988.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVRQRILKKYGWMVLDNL
                     IEDKVLETAISEGFFYVKEYNRGKKIVIRCLLCFTKKISIITVVK"
     gene            11288..12271
                     /locus_tag="VUX16_001005"
                     /pseudo
     CDS             11288..12271
                     /locus_tag="VUX16_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12261..13373)
                     /locus_tag="VUX16_001006"
                     /pseudo
     CDS             complement(12261..13373)
                     /locus_tag="VUX16_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            13635..13832
                     /locus_tag="VUX16_001007"
     CDS             13635..13832
                     /locus_tag="VUX16_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8123989.1"
                     /translation="MYIRVKNLREDSDYNQSQIAQYLNCSQSTYSRIESGIQDIPTQF
                     LKKLAKLYGVTTDFLLEMDKE"
     gene            14103..14243
                     /locus_tag="VUX16_001008"
     CDS             14103..14243
                     /locus_tag="VUX16_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123990.1"
                     /translation="MEKTQTGADLPQVVIEGYKVTVRVTDKPLSLTDVLDDLLGRQLE
                     KI"
     gene            14343..15911
                     /locus_tag="VUX16_001009"
     CDS             14343..15911
                     /locus_tag="VUX16_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET8123991.1"
                     /translation="MTRACTYLRLSRDDGDNVESNSIINQRSLLRDYARRHDFTILEE
                     FVDDGISGLTFNRPDFNRMMVMVNNKTIDTIIVKDLSRFGRDYIETGKYLQRIFPAMG
                     IRFISVNDHYDSLTADTNETHLVMPIKSLINDSYCRDISTKVRSTQKAKRQKGEFIGA
                     FAPYGYRKDHNQRNHLVVDEAVRSTIETIFALKLEGYSSNAIANFLNQAGVETPLQRK
                     RACQERIKGFYGYRHKWDTKMVNRILTNRVYTGTLEQGKQTKLNYKSQKSVAVNPEDW
                     VRVEDTHEAIISTSTFSIANNLLLRDVKHGKNTPDLFAGLLFCGDCQAQLLQRKLRYK
                     DKETVQYICSTYNNGQGCSRHAIKEDVLTDLVSTIVHQHLDWKSYLVKSIPDYLDQEH
                     FLEVDFTSLISERQKYEQLLQSLYLDLDDGLINETEYQEFQRSYRQKLKQIEDTIVQK
                     KELAQTLYDKLQDKETWLEQLSTIQHEQELNRLTLVTLLDRIIVHEQQALTLMFHDVA
                     ELSLLQQFSNMEVV"
     gene            15911..17527
                     /locus_tag="VUX16_001010"
     CDS             15911..17527
                     /locus_tag="VUX16_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET8123992.1"
                     /translation="MARTKNRSRVETVEKIPLQTYRTGIYIRLSKERTESWRHKSQSL
                     KTQESLARTFAQEKGLTVTKCYIDYEYSGTKFNRPAYQDMMEDIKRGVINCILIRDLS
                     RLGRNYIEIGRLIDKVFPFMGVRFISINDNLDTLNGLEDKKSFEVEIKNLVNDLYSKD
                     ISKKVMSYNIHQASQGYYIGTSAPYGYRIDRQEAGARLVIDNQVKPILEFIFQQAIEG
                     VSISQITTELNHRGIAVPQSYRGTGQLYRSEQDIKRWHAGNLLRLIKMPVYRGVLIQR
                     TRNKSLSEEDYIHFENAQEAYVSKDNYEKILFYLDSRKSVKKTSIVRTPNRYRGLVYA
                     KTKSTQMVRRCRHFSNNKSDYDYYYFTDYIYDSETTERKTVYISENALDKIIVELIQS
                     EMKRLGTVETLLPRLETKKDDCLKTYHKQITCHQWTITQLQAELSDLYASFSLNRSER
                     EVYLSQKNEIIAKIETISQEIALCETSIKQIEEEHSKQVNWVRHLAKSQNQVVLTAEL
                     LNALIERIEVDVDKTVTVTFSCQIGGGEHD"
     gene            17520..18959
                     /locus_tag="VUX16_001011"
     CDS             17520..18959
                     /locus_tag="VUX16_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET8123993.1"
                     /translation="MTKIALYLRLSVDEADTDESNSITNQRYLLNNYLDQTPEFKNWE
                     RLEFVDDGFSGTSLKRPAFQRMMADVKAGTIRHIIVKDLSRFMRDYLELGNYLENIFP
                     FLGVRFIALNDHYDSLVSEHNGLDIDVPFRNLLNDFYAKDVSEKVKSAMNSMKRSGKN
                     MSWLPPFGYIKDPNDRFKIIIDEEVAPIVRRIFRLCIEGMGTQKIAMLLNSEQTITPA
                     ERKMQVSQARYTKSIIITAEQKRNVWTRSGILQILKNEAYKGTYLFNTRTTVNGKQIR
                     RPESEWERLDNNHEAIVSSEDFDKAQQSLTSRISGTKSQVCNQPEEVLLRGLVICEHC
                     GHRLLRYSHNNNNNYFYCCYCRSQGQNMKSCRIDRIEEAIEKELKSRLPMNSPKLSKT
                     NLIREVERLKTQKVSHFQDYKEGLMTRETYMEKRQNLDNSIMEIEEQLKVVGRENIAF
                     DKKLTREVVDTHIERIVVNGQGSFTVVYK"
     gene            19071..19166
                     /locus_tag="VUX16_001012"
                     /pseudo
     CDS             19071..19166
                     /locus_tag="VUX16_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin BlpN"
     gene            19410..19559
                     /gene="blpO"
                     /locus_tag="VUX16_001013"
     CDS             19410..19559
                     /gene="blpO"
                     /locus_tag="VUX16_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET8123994.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CVTTV"
     gene            19663..19782
                     /locus_tag="VUX16_001014"
     CDS             19663..19782
                     /locus_tag="VUX16_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET8123995.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSPKKDTDSTP"
     gene            20080..20244
                     /locus_tag="VUX16_001015"
     CDS             20080..20244
                     /locus_tag="VUX16_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123996.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            20241..20645
                     /locus_tag="VUX16_001016"
     CDS             20241..20645
                     /locus_tag="VUX16_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET8123997.1"
                     /translation="MKIFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSLVFQF
                     FLVVINLASILVTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAILCLTIMLLLIWGLKYYKK"
     gene            20806..21231
                     /locus_tag="VUX16_001017"
     CDS             20806..21231
                     /locus_tag="VUX16_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET8123998.1"
                     /translation="MKKQKIKSLLLVPLVFASITAGLAYAEEQPTTSSTQANDSSLVA
                     PDLPSAKEKVEHKPSVVTPEEYEKNVTDFKKIDIEAVRQSFTGDQLEHTIYFGRKTCS
                     HCRQFSPELKEFNNLIEKKLEYYDLDGKDFDGEAREFLF"
     gene            21374..21832
                     /locus_tag="VUX16_001018"
     CDS             21374..21832
                     /locus_tag="VUX16_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8123999.1"
                     /translation="MKSSEETVTESVRDENTRSDSMNISDKVVSDSKGMSDKKRTEMK
                     ISNANSENSGKVESTNSTSEAKTTQSGNLAMLDNKNQLETLKPIFDAAQENKTSLTDV
                     KDADYVSESITSNEKLLLKTGEEESYQLIRLAVAFFMASIMIKVKQKIHK"
     gene            22078..22311
                     /locus_tag="VUX16_001019"
     CDS             22078..22311
                     /locus_tag="VUX16_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HET8124000.1"
                     /translation="MDTKMMSQFAVMDNEMLARIEGGDVSDIYRGYANQVSPFGSYPP
                     ILKNSGPFPVSGYCPRGYHDRGYIGAGFHLCGI"
     gene            22343..23032
                     /locus_tag="VUX16_001020"
     CDS             22343..23032
                     /locus_tag="VUX16_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET8124001.1"
                     /translation="MKKYQLVFKISAVLSYLFFVFGLSQLTLIVQNHWQFSSQVGNFF
                     WIRNILSLLFSGVMIWILVKTGHGYLFRIPRKKWLWYSILTVLVVVLHISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYVTLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFLSLPSLLDIFVFATFGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            23075..23323
                     /locus_tag="VUX16_001021"
     CDS             23075..23323
                     /locus_tag="VUX16_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124002.1"
                     /translation="MYKHLFFLDSKTLDRLTPYIIVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLDLKNDV"
     gene            23353..23964
                     /locus_tag="VUX16_001022"
     CDS             23353..23964
                     /locus_tag="VUX16_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET8124003.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            24126..24920
                     /locus_tag="VUX16_001023"
     CDS             24126..24920
                     /locus_tag="VUX16_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET8124004.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            24917..25552
                     /gene="trmB"
                     /locus_tag="VUX16_001024"
     CDS             24917..25552
                     /gene="trmB"
                     /locus_tag="VUX16_001024"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET8124005.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            25678..26157
                     /gene="rimP"
                     /locus_tag="VUX16_001025"
     CDS             25678..26157
                     /gene="rimP"
                     /locus_tag="VUX16_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET8124006.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            26201..27337
                     /gene="nusA"
                     /locus_tag="VUX16_001026"
     CDS             26201..27337
                     /gene="nusA"
                     /locus_tag="VUX16_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET8124007.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            27359..27652
                     /locus_tag="VUX16_001027"
     CDS             27359..27652
                     /locus_tag="VUX16_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET8124008.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            27645..27944
                     /locus_tag="VUX16_001028"
     CDS             27645..27944
                     /locus_tag="VUX16_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET8124009.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            27961..30753
                     /gene="infB"
                     /locus_tag="VUX16_001029"
     CDS             27961..30753
                     /gene="infB"
                     /locus_tag="VUX16_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET8124010.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKSAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            31004..31354
                     /gene="rbfA"
                     /locus_tag="VUX16_001030"
     CDS             31004..31354
                     /gene="rbfA"
                     /locus_tag="VUX16_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET8124011.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKAIGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            31633..32416
                     /locus_tag="VUX16_001031"
                     /pseudo
     CDS             31633..32416
                     /locus_tag="VUX16_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            32418..32600
                     /locus_tag="VUX16_001032"
     CDS             32418..32600
                     /locus_tag="VUX16_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124012.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            33015..33248
                     /locus_tag="VUX16_001033"
     CDS             33015..33248
                     /locus_tag="VUX16_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET8124013.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            33248..34582
                     /locus_tag="VUX16_001034"
     CDS             33248..34582
                     /locus_tag="VUX16_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET8124014.1"
                     /translation="MTDERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            34592..34846
                     /locus_tag="VUX16_001035"
     CDS             34592..34846
                     /locus_tag="VUX16_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET8124015.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            34942..35337
                     /locus_tag="VUX16_001036"
     CDS             34942..35337
                     /locus_tag="VUX16_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET8124016.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            35750..36199
                     /locus_tag="VUX16_001037"
     CDS             35750..36199
                     /locus_tag="VUX16_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HET8124017.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVVPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            36186..36746
                     /locus_tag="VUX16_001038"
     CDS             36186..36746
                     /locus_tag="VUX16_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124018.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAACALIDLAFKELGLHKIELTCFGYNLQSQRVSEKLGFTLEARI
                     RDRKDAQGNCCDDLRYGLLRSEWEVI"
     gene            36746..37324
                     /locus_tag="VUX16_001039"
     CDS             36746..37324
                     /locus_tag="VUX16_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET8124019.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQDLLDNFHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQHQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            37317..39968
                     /locus_tag="VUX16_001040"
     CDS             37317..39968
                     /locus_tag="VUX16_001040"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET8124020.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPELGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            40063..41160
                     /locus_tag="VUX16_001041"
     CDS             40063..41160
                     /locus_tag="VUX16_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HET8124021.1"
                     /translation="MAQNKLVRRNFDISFNELYDMYNDGELVIKPEFQRLFRWSLTQQ
                     SLFIESLLLDMPIPPIYVDEQEDGRYVLVDGLQRISSYLNFRGITLDSPELTAIDPDD
                     DDCEIDFERVEPGFQLSGCEIIDDLNGKEFDELSIEEKRQLKRTFIRVEVLTKENPKE
                     IKYHMFKRLNSGGALLSKQELRNSNIRMIDEKFINFINELANSEDFVELTHYMTESDK
                     QQMKRAEVVLRFFLFKNKFINDNPDVRMGFLDDELTTYLEEVSSQKFPFEYETEKENF
                     LSLVSYLKNHFGSVIFSGISKNNTISKRFVQYNYDGFMQYFSKESNRDSSITIDKINE
                     IKNSDEYKQYRTGGLENSRKRVEVIAGKVNE"
     gene            41153..41896
                     /locus_tag="VUX16_001042"
     CDS             41153..41896
                     /locus_tag="VUX16_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124022.1"
                     /translation="MSDIRDSLDKILAVSIDSIKDEQNFLNLVLSDSPEGNILKELAI
                     FKDNGALYKLIFSVYATFEYTIKECCNTALLTIDKNSLDSLTDELQMLTFRQKLDELR
                     KKIIEKREDNTVIKPLTDLHIKIKQQTEFNSNENMIDTKSNLNFNNFTEILEIFHFDK
                     KKYKSYSIIIDSIITYRNMIAHGNRKDLTEINIRQYIPGNYKIITLHKENNRLYFEDL
                     CSDMINLLKLFCQDLTDYVNEQKYLRQDK"
BASE COUNT        13722 a         7311 c         8857 g        12107 t
ORIGIN      
        1 taggtcatat gggacttttt ttctacaata aaataggctc cataatatct atagtggatt
       61 tacccactac aaatattata gagccgcttt tttgtggtcg agaactattt tgtcctaggc
      121 tcttttcttt tttgtgataa cttttccaag tcaatcttgt tatgatggtg ctatcttacg
      181 gaaaaaggag atggcactat tgatgttaaa taaaatgaaa gtgagttttt tgcttggttt
      241 aggtggtcta gcagtcatga gctttgtggt gatgatgggc tacactattg gttctcagtc
      301 tgtgacccat cacatgcaga aacaaatcca gactgaagct cataaactat tgacccaaga
      361 gaaagaaaag gagaaagcaa gtgtcctctc agatgagttg gtcaaagaat ttctcaccca
      421 atactacact aagggaaagc tgggggagaa caacaaccgt attaagctct atatgaccga
      481 ctctgcttat aaggaagaag tagctcgtca agaagattcc atcaatcagg tctataagga
      541 ctatatgttg gattatcgct ttgagactgc tcaaatctat gtcaatacag aagcaaatga
      601 agctcttgcg gaagtatcct atcaggttgt ttatgtgtca gatgttagtg ataaggctca
      661 gaaaagtaca caaacagaaa cgaaatctct taaactatct tataccaaaa tgtcagataa
      721 atttcttgtc aagcaggtaa ctgtttggaa cggaaagcta gagaacttaa aagaagtttc
      781 tgatggagct gattcaagca ttccagatat tcaaggcact actacaagtg agaccaacta
      841 gcaggagtta cccttctgct tttttgatag ggagatgaga tgacaagaat tgaagcagtg
      901 aaacaaaaag caatcttaga ggttgcagaa agtctaggtt attcttttaa acgactatca
      961 gggcaagtct atgaacatcc agaacacgat tcctttagga tttttgcgga taccaatact
     1021 tttaaatggt tttcacgtga catacaggga gacgtgattg attttgttca gttaataaca
     1081 ggagtgactt ttaaagaagc tctgtcttac cttgaaacag gggactttga acagactaag
     1141 atggttgaag agacttacca accctttcgc tattatctaa gggaagaacc attttaccaa
     1201 gcacggatat acttgaatga cattcgtggt ttaagcgatg acactatcaa tgcttttggc
     1261 agacaagggc tgttagccca agctcattat cagacaaaga tctttcaaga atcagttctt
     1321 gtttttaaga gttacagtca tcatgggcaa ctagaggggg caagtttgca ggggcttgtt
     1381 aaaaataatg agagacatga tcgagattat ctcaagaaaa tcatgaaagg ttctcatggt
     1441 tatgttggga tgagttttga tataggaaag cctgaacgcc ttatcttttg tgaatcagtg
     1501 attgacatga tgagctatta tcaactccat cagaatcagt tatcagatgt gcgtttagtt
     1561 tctatggaag gtctaaaact ctctgtgatt gcgtatcagt ccttacgatt agtagctgag
     1621 gaacaaggca aacttgagtt tttagatact gtaaaaccaa gtcgattaac gcattacctt
     1681 catgccatac aagagacaac cacttttttt cagactcacc caagtctgat aaccttagct
     1741 attgataatg atggagcagg gcgagacttt tgtcagaaat tatctgagaa aagccttccc
     1801 attgaaacag acttaccacc attacaggaa ctggaaacta aagctgattg gaatgatgtc
     1861 gtgaaaagtc agaaagacct ttctctaaag gatatgatcc aatcggccaa gttacaagtt
     1921 atccgaagca atcctcctcc tagaaaaaat accgctttag agttgtgata acaaaatcaa
     1981 gtttcttagc ttaatctaga aagtgataag gaggacaccc tatgagtgtg attgaacgcc
     2041 tggctgaaag agtagctagg caagaggaaa aagttgcgaa agaaacggaa aagctaggaa
     2101 cctatcgtga gcagttacag gcagctatgt atagcatatt tgtcaagcgt cagcagtcga
     2161 gtcatcttac ttttgatgag gctttaaacc aggcgtttgg taagcaggaa aatcattcac
     2221 aggtaatcga aaatagaaat gaggaaacag aatgacaaaa gattggactt ttgaccaatc
     2281 cctagatgat aacacaccaa cgtcttccac agaagaacgt gcgaagattg cagccctatt
     2341 tcataaggaa gagaaagaag aaactggaga agttaattat gtggcagcct ttgaaatgga
     2401 gcaacaaaaa gctaaggaga aatcagtttc aaaaccaaaa gttcaagagc aatccacacc
     2461 aaaagaagtg ccctcttcaa ccattaccag tgactacaag caacatctag ccaatgtgat
     2521 ggctcaaaac aatgaggaca ttcttcaaag tcaaaagaaa atcgaagagc tgaaccagtt
     2581 gattgatgac aaaaataagc agaataagaa attacaagcc atttcagaag ctattgatga
     2641 cttgtaagta cgagcagtcc ttatgtgggc tgctttttac gagggggaac agatgaggtt
     2701 attcaaaaaa caaacgcaca atcaagatag ttttaagcga ctcattcatc gcttatcagg
     2761 aatgtctgag actgacttac acaaagttaa ccaattatta gatgtcgttt ttgatgctac
     2821 aagtcaaact atccatgaag aaacaatgac tcctaaagat atgccaaagg agcctatatt
     2881 agatgagact attactgaag ctaagaataa actgaatact gagcaactgg aaaaacggat
     2941 agaacagttt agacaggcga agaaaccgaa aagcggataa tgcaccaaaa atggtgcgtt
     3001 atccattttt tgtgctataa tgaaagtaac gaataggagg tcttatctat gattggagag
     3061 aatatcaaat cattacgcag aacacacgat ttgacacaac cagagtttgc caaaattgtt
     3121 ggtatttcaa gaaatagctt gagccgttac gaaaatggga caagctctgt ttcgacagaa
     3181 ctcattgatc gaatttgcca aaaattcaac gtgtcatatg tcgatattgt aggagaagaa
     3241 aagatgttaa caccagtaga agattatcaa ttgacgctga aaatagaagt catcaaagag
     3301 cgtggagcag cggttttatc tcaactgtat cgctatcaag atagtcaagg gattgctttt
     3361 gatgatgaga ctaatccttg gattttgatg agtgatgact tgtctgacct tatcaatacc
     3421 aagatttatc tggtcgatac ctttgatgag gtagaacgct acaatggtta tttggatggc
     3481 attgagcgta tgttggaact tgctcgtcat caggtggtgg cttaatggca ttagaagcat
     3541 ttcgtcaaga tgactttgac ctagccctga aacgcaccat ccgttcttta acccgaggca
     3601 agacggtttc gactagccca caagctattt tacttggggg acaaagcgga gcaggtaaga
     3661 cgaccataca ccggattaaa caaaaggaat ttcaaggcaa tatcatcatt attgatggcg
     3721 atagctaccg ctctttacac ccgaattatc ttgtcttaca agaagaatat ggtaaagata
     3781 gtgtggatta caccaaattc tttgcaggaa aaatggtaga gcacctcgtt gatgaactca
     3841 gcaaagacgg ttatcatttg ttaattgaag gaaccttgag aacgacagag gttccaagaa
     3901 aaacagctca gctattgaaa tcaagagatt atcaagtatc actcgcattg attgcgacta
     3961 agcctgaatt gtcctatctc agcaccttaa ttcgctacga ggaagtctat gccgagaatc
     4021 caagccaagc tagagcaact tctaaagagc atcacgatgg tattgtagaa catttggttg
     4081 ataatctaag agagttagaa actgataaac tctttgatca gattcaaatt tatcaacgag
     4141 acaaacgctg tgtctatgat tctgatacag acgatggttc agttgctgat gtgttgcaag
     4201 attgtctctt cggaaaatgg agtaaggttg aggaggagat gattaaggaa gctaaagaat
     4261 atttaaaacg attgagtaaa agtaataatg aaaatatctt agtatgaaat agaggtagaa
     4321 aatagtggaa acagtaaaca caattttagg aatagtagga tctatatttg gcataattgc
     4381 tacagcaatt tctttaaaaa accagaacga tattaaaaaa attataaaga attccaataa
     4441 tagccaaaat ataggtaaca atagcagtaa taatgtacag aatattggtg atgggagata
     4501 aaaatgactg aatcccaaaa tatcggaaat tttagtaata ataatgttca aaatatgtat
     4561 gtaacaaata ttgagcagcg tacattgatc ccaactgtta tttttcaact tttaaaatat
     4621 gttgaaggat ttcactctca aaacgatgaa aagtttttac ttgaacaacc agctgaatta
     4681 aaggaaaaac tacaatttaa taattctagg agatatatta gattatttaa agagggtctc
     4741 agtaactata tttcactaga aaaggtatta aaagatgaat tcacagatag tcaaagagta
     4801 gttgaaaata taaagaatat ttttatggat catactccta tagatgcaga aggaaatccg
     4861 atagtaggta atggtgatga atgtttgaaa aagatgcatg atgacataaa agaaagaatc
     4921 gcgagagatc ctaatttttt atctagtcaa attgatgacc tagaattgga taaatttatt
     4981 attgcacttc ttcaatatgg agttatagag tgtcaaatat tattgaatcc aaataattat
     5041 atggagtgta atgatgttat tacttgataa aaatgctgag cctaaaaaga ctatttttta
     5101 tctctcagct attgtacatg gcttgatttt aaagaggata gtcaatatag aaaatcttta
     5161 tatagagctt caaaaagaaa ttgaagatga actaaattat gattttttta tattagcact
     5221 agattttctt tttctattag ataaaataag agttaataat gaaggagata ttgagagtgt
     5281 tcattaaaag tttgagtatt atcagtaaaa atactgatgt tgtattgaga aaaatagaat
     5341 ttaaaaatgg aattaatttc atagtagatt cggagaagtc ttataagcat aataaagttg
     5401 gaaaaacaac atgcttaaaa ttactggatt taagtttagg ggcaaaaagc aaagatgcca
     5461 tttttaaaga ttatgaaaca cagagtgtta atgaacaatt aagattgttc attgaaaatc
     5521 aaaaaatcta tactgatatg gtgttaatag atgatttcaa ccatccttct aaagaagttt
     5581 ctataaagac agaattgttt aacagaggta aacggtatat taatggagag caaacttcat
     5641 atgatgaagt taacaaatat ttaaatgaat tattgtttga aaaccgctct caaaagccaa
     5701 gttttagaag tgcgataaag tcatttgtac ggattttaat gactaaggat aatactcaat
     5761 ttttaaaagt attagataat ttttcaaata tttcggaata tcgcgctgta tataattatt
     5821 tgttcgatat ttcagatctt gaaaatgatt tagagtttgg taaattaaaa caggaattaa
     5881 aaaatataaa aagtaaggaa aataattata aaaaagtaaa tactgtagat gatgtagtaa
     5941 aaataaaaca aatcaatgtt gcaattgaga aagaaattga ccggttagaa aaagaaataa
     6001 atgatttagt agataaaaaa gcatttgaga aaaatagaat tcatatcaac gatattagaa
     6061 aaaaatacga ggagataagt cgacaattaa gtaaaattga ttttgacatt ttacagttac
     6121 aaaaatatat caaagaggct gaggagaaat cccaaagaat agtaaatcaa gaactggcaa
     6181 atgacttttt tcaagagatt tccgaattgt tacctagtat tactaaaact tttatggatt
     6241 tagttgaatt taattcccaa ttgagtagaa ataaattgtc ttattttaat gatagaatgc
     6301 aagaattgat aatggagaag gaagataaag agaatttatt gacgaaattg accgaagaaa
     6361 attcagaatt tatatcttta gttgaagaaa acaaagtaga tttatattat gataagttaa
     6421 atcaactaga tgagttaaaa ataaaaaaag taaaaaatga atcaacaatt actagtttag
     6481 gtaacattga ggagcaaaaa aatactttag aaaaaagact ttctaaacta gagatgattg
     6541 ttaaaaataa tgaagcagaa tatcagaaaa aaatggatat ttttaatagt tattttaaga
     6601 gcgttgcaga tcgaataaat aaagaacaac ctgtcttgct ttataatccc aagacagatg
     6661 aatttccagt ttcaattggc caactatctg aaggtacaag tacagggact agaaagtccc
     6721 ttatcgctgc atacgatatt gcttatcaac tttttgctag agaaattaat aaagcaactc
     6781 ctaaatttat tgttcatgat gttcttgaga gtattgaagg tgatgatatt agggcgttag
     6841 ttgacgaagt ggaaagcaat caaatacaat atatttcagc aatcttaaaa gaaaagttag
     6901 tatcctctgg tatgtcaaca gagaaacaaa atgagataat tgttctacaa ctttctatga
     6961 aagatagatt gtttgaaaga ggaaataatt gttagataaa atataagtct tgaattttaa
     7021 aaggaagttc aagacttttt tgtgataact tttccaaatc atccttgtta tcctaatgtc
     7081 attcctaaga aaatcaaatc ttgatttttc actgggggtt tgggggcgaa gccaccatag
     7141 tttcttatcg tcggctgaca aacctgtaag gttttggttg gctgacgatt agattttggg
     7201 ttattgtgga cacaataact gagctcgcaa aagccgaaaa agaacctttt gaggctttta
     7261 ggaagtgtac tgacagtgtg aggctgcctt acattgtcag gcaagtaatt ttttgaaagg
     7321 ataaaaccat gagacaagat attaagttaa tcagaaaaca attcaggata acaagacagg
     7381 aggataatca gataaaagaa atgatgagag aacaacaatt ggagagtttc tctgaattcc
     7441 ttcgccaaaa tttattgaaa aaagagtctc acgaagacgt tttgattcgc tggtttactc
     7501 tctggcaatc tcaaaagatt gaacaaatca gtcgagatat tttacaggtg actaccttgg
     7561 ctgaacaaag ccaccaagtt acggcagagc acctacggat tatcttgacc tgcgtacagg
     7621 agctaatagc agaggttaac caggctagtc cacttagtca agactttcgg gacaagtaca
     7681 tgggaggtta gggatggaaa atcgttaccg caccaatctt aaaaaagttt ttctgacaga
     7741 ccaggaactt gcggtcttgc acgaccgtat cggacagagt cgctgtaaaa atttctctgc
     7801 ttatgccaga aaagttttgc ttaatcctaa catgaccttc ctaaccattg acaccagcaa
     7861 ctatgaagac ctggtttttg aattgagacg aattggaaat aacatcaatc aaattgcacg
     7921 aacggtcaat cagaaccaca tcttaacacc aagtgaccgt gagttgttgg tacagggcat
     7981 ttgccaactc atcaaggaag ttgagaagga cttcaacata aagtgccagc agctgaagga
     8041 gttttatggt agtcactaag cattttgcgg ttcacagcac caagtaccgc aagagcctca
     8101 tcaagtatat tctcaatcct gaaaagacgg agcagttgaa gttgatttct gattttggca
     8161 tgaggaacta tttggttttt cctagttatg aggagatggt ggagatgtat gaggccaacc
     8221 tcactaacaa tgataggctc tacgattcta gaaacgaccg ccagcaaatc aagcagacca
     8281 aaatccatgc ccaccacttg attcaatctt tttctcctga agacaagctg acaccagagg
     8341 aaatcaaccg cattggctac gagaccatca aggaactgac aggtggaaac tttcgtttta
     8401 tcgtgacgac ccacactgat agaaaccatg tgcataatca tatcctgata aactctgttg
     8461 atcttaactc tgacaagaag ctcaaatggg attacgttca agagagaaac cttcgcatga
     8521 tttctgaccg cttggccaag gaagcagggg caacgattat ccagcctaac cgttattcgc
     8581 acgagaagtt tgagacttac cgcaagacca atcataaatt tgaactcaag caaaggcttt
     8641 attttctcct ggaacacagc aacaactttg aggaattttt ggccaaggct cctgctataa
     8701 acgtggagat ggatttttcc cacaagcacg cccgttttct catgaccgac cgagagatga
     8761 aacaggttat tcgcggtaag caattggaca agcgacagcc ctacaccgag gactatttca
     8821 gagagcagtt tgcgacacga gccattgagc agcgattgga ttttattttg cctagagccc
     8881 gtgacctctc tcatcttttg gaaatggcag agcagttaaa cctgacaatc tctcctaaga
     8941 aaaagcatgt gacttttact ttgaccgaga aaggtcgaac catttccatt gaaaacaaaa
     9001 agattagcac taaacacttg tacgatgttc agttctttga ggattatttt gatcaaagag
     9061 aatccctaac agatcctgac ttaactaacc tggtatcaga ctttgagatt tatcaagagg
     9121 aacaggacaa ggacaaactt ccaagtgagg aactcctagc agcctacaag gagttcaaag
     9181 agaaacgtga ccagattcag gagtttgaag ttgttctagc tgaccatcag attgataagg
     9241 tggtcaagga cggtcttttt attaagatga attacggtgt caaaaaagac ggcttggtat
     9301 tcataccaaa ccgtaatcta gatattcacg agaatgagca gggtaagtcc caccatgtct
     9361 ttatacgaga gaccgcccag tttttcattt ataacaaaga cagtgtagac ctcaatcgtt
     9421 acatgagagg gcgtgaacta atttgtcaac tcactcacga cagcaaacat atccctaaac
     9481 gtaggcgacc aactattgct agcctcaaag agaaaatctc agaggttaat cttcttattg
     9541 agttagacat caacaaccaa tcctatcagg aagtcaaaga cgagttaatc aaagacatcg
     9601 cccagctgga tttgaccatt acaaatctgc aggataaggt tgctcatctt aataaggtcg
     9661 cagaaatcct gcttaatctc aataactccg atccagaaaa tcgccgactg gccagatatg
     9721 attacgtcaa gatgaacctg actgcggcta taaattttga acaagttgaa caagagattt
     9781 ctcgctcaca acaatcttta aaagacttga tagataaata tgaatttaaa gttaggagac
     9841 tggaaaaatt tgttaaaaat attagtagta tttacgacta cccctttgga ggtaaaacat
     9901 atacaaataa ctatcaacct gattttgaat aaacatttgt cttttagatg atttgtatac
     9961 gatattttat aaatgattac cactttttat ttttcaagaa tcaaaataac cgtattaatg
    10021 tatatttttt atatagtaca gtattaaata ggttatctga agtgacaccc aaaaattgtt
    10081 atataaagaa aaaggtacta gatatgcttt ttcatatttt aacttaaata aaatggcaaa
    10141 ctaaaattgt aaaaataatt tagcgaatta aagaatattg aactataaat taaatcagtg
    10201 agatgtgttt actaaatcaa aaaaattaaa ctaaggtatt tcatattttt agttaatctg
    10261 gtagacttta gtaagttgta taatatttaa gtcaattttt agaggaggct ttaaaatgta
    10321 agagaggaag agagaataat ggataataat tttatgagct ttccagatag gattggaact
    10381 aattcaagta agtggaggat ttttgaaaca aatcctaata tggtttcatc ttctttagca
    10441 gatatggatt ttgaaattcc tgagttcatt agaagtgttt ttattgatta tatggcatta
    10501 gattttatgg gctatagtta tcaatctgaa aaggctttag aggctatttt aaattgggaa
    10561 aaaaagaaca tgggtactat tttgataaag aaaaactaat tttgctggat agtgttatga
    10621 caggagtagc taatgcaatt caggcattca caaatttggg agatgctgtt ttaataaatg
    10681 atccagtata cccttctttt aagcaaataa ttgaaaataa tggcagaaaa cctgttttta
    10741 gcgagttaga aattaaggat ggggtatatc gatttaattt tgaaaagttt gaggactgta
    10801 ttataacaaa caaagttaaa gtttttgttc tatgcaaccc tcataatccc ttaggtaggg
    10861 cttgggaaat tgctgagtta aataaaattg gaaacatttg tttaaagtat aatcccgact
    10921 ttatcactta atttttacca agccctactt aaccccttgg tacatctgga tttcccaact
    10981 attccccaac ttttgtttgt tatatatgat tatgtatgat tatgtatgat tgtgtatgat
    11041 tgtgtatgat ataatagagt atggcattta ttaaaacaac aaccaacaaa gaaggacgta
    11101 ctcatgtcta tcttgtggaa ggatatcgca aagatggaaa agtcagacag cgtatcttga
    11161 aaaaatatgg ttggatggtc ttggataacc tgattgaaga caaagtccta gaaacagcta
    11221 tttctgaggg ctttttttat gtcaaggagt ataatagagg taagaagatt gtaataaggt
    11281 gtttgctatg tttcacaaag aaaatctcga ttataaccgt cgtcaagtag gcttctatac
    11341 gcttgaagag atagttccaa aggaccactt tctgcgttag ttggaggaaa ctgtcgactt
    11401 ttctgtcatc tatgatctag tggagaatag ttattcctca gacaagggac gtcctagcct
    11461 tgaccctgtt atgctggtca aaattcctct gattcagtgc ttctatggca ttcgctccag
    11521 gcgtcagacc atcaaggaca ttgagattaa tgtcgcttat cgttggtttc tgggcttgac
    11581 tctggacgat aaagtgcctc attttaccac atacggtaag aactacagtc gtcgttttgc
    11641 tgaaacagaa ttgatcacgc gtatcttcga gcatgtcctc catctctgtt tgactgctgg
    11701 cttagtggat acagatgaga ttttcatcga cggaacgcaa atcaaagcag ctgccaacaa
    11761 ccataaaaat agacgacaag aggttgaggc tcaagctaaa tggatgagtg aacaactcga
    11821 caaagaaata gcacaagatc ggataacaca tggcaaaaag cccctaaagc ccgccataaa
    11881 aggcgaggct aagaccaaaa agatgtccat gacagccaag ctttccctgc ccttttcgca
    11941 aagctagcac cgtttcaccc caactatatc atcgctgact ctggttataa aaatcccagt
    12001 attgccaaat gtctactgaa ccagcatatc acgcctgtct tttcctacac cagacctcgt
    12061 ggcaagaagg gcatgttacg accgaatgat ttcatttatg acgagcatta taacgtctac
    12121 ctctgtcctg aaaaccaagt cttacactac agcactacca accgttctga ctatcgagaa
    12181 taagagtaac cccaagactt gtgccacttg tctactccta aaccgctgta cccaaagtaa
    12241 gaccaagcag aagctggtca ccagatatgt ctcgttacta ctttttgaaa attcttgctt
    12301 tgggtacaaa tggataataa aggacaggaa acacatactt tgggattact cttatactca
    12361 cggtagcctt ctcgagtggt agtgagatag cttaatactt gattcctgga cagacataat
    12421 ggtcataact tgcatcataa acaaaattac taggccttaa gttccccttt actccctttg
    12481 gacgagtata agggaaaaca ggaatgatat tacgttctaa caaataatgg gcaatagctt
    12541 gggtcttgta acctgaatct gcaataatat agtgggggga gaatggctct aactttgaaa
    12601 atagggcagg gaaagcttga ctatcatgaa catttcctgc ttcaaccgta taagctaagg
    12661 accatccatg cttatcacaa gcaacttggg cagaataggc aaatacttcc ttgtgttcgc
    12721 ccttgtgaaa caaaccacac tcgggatctg tcgttgagat tttcttttcc ttagcttcac
    12781 tttcttttgc gggctttaag gacttttttc gtgttttttc ttatctaaat caatctcaac
    12841 tgccaattgt tcactcataa atctagcttg ttggtctacc atttccttac gggacttgtg
    12901 actattagct gccactttga tatgggtacc atccacaaat atttcagaag aatcaattaa
    12961 ggcaacatac aaagcttggt tgagaacttg ggaaaaatct cagaaatgag ttctttatct
    13021 tgaaaacgac ggctgtaatt ctttccatag gcagtaaaat gagggacctt atcatctaaa
    13081 gttagtccaa gaaaccaacg ataggccacg tttacttcaa tctctttcat ggtttggcgc
    13141 atggaacgaa tgccataaaa acatttgatt taaggaattt tgactaatat gacgggatca
    13201 agactaggac gaccattatc tggactatag gtatcttcta ccaagtcata gataaagtca
    13261 aaatcaacct tggaatctac ttgtcgaaga aagtgatctt ctgggaccaa ttcgtctatt
    13321 gtatagaaac catattactt acgattataa tcaggttttt ctttgtgaaa cataaggaac
    13381 acctcacaac tcttcttacc tctattatac gactttacac aaagaaaagc ccttggaagc
    13441 ttgacttcca atgactgtat cttcggtctg aaacttctag agtcaacaaa gactttggaa
    13501 gttttcaata taatctgtta ttggacggtt acgtagtttc tgattattct ttaaaataaa
    13561 ttatttatgc aagttttgca tagaacccca tctttatttt tagaattact aaaatagtaa
    13621 ttggaagggg ttctatgtat attcgggtaa aaaatttaag agaagacagt gactataatc
    13681 agagtcaaat tgcacaatat ctaaattgtt ctcaatctac ttattccaga attgagagtg
    13741 gtattcagga tattcctact cagtttttaa aaaaattagc aaagttatat ggagtaacta
    13801 cggatttttt actagagatg gataaggaat aatacccttc ttttgttcct tgacaactga
    13861 atagaccaag gtgggacttt aatcatttgt ggagcaagtt agttagatac gctgtgatat
    13921 gagcgagaat tatcagctat aaaatagagt ggtactctat ctgccatgat acaagtgaag
    13981 ataatgatac ttctaaccgt ttaggctgcc agcgagaaag gacagcgggt gtaagcccca
    14041 tgtagaactt aaccagttct acccattgag gtcaacattt tgacgtaaag gaaataacat
    14101 ttatggaaaa aacacaaaca ggtgcggatt taccgcaagt cgtgattgag ggctataagg
    14161 tgacggtacg agttaccgat aaaccattaa gcctaacaga tgttttagat gatttactgg
    14221 gacggcagct ggaaaaaatt tgatttttta gcggacaagt cttgataaat gatgtaaaat
    14281 agaatagtag aacctcagtc cttaatcggt aagcacctaa ataactgatt aaggagacaa
    14341 acatgacacg agcctgtact tatttacgct tatcacgaga tgatggggat aacgtagaga
    14401 gtaattccat catcaaccaa cgctcgctct tgcgagatta tgctaggagg catgacttca
    14461 ccattttaga agaatttgtg gatgatggta ttagtggact gacctttaac cgtccagact
    14521 ttaaccgtat gatggtaatg gtaaataaca agaccattga taccattatc gtgaaagacc
    14581 tgtctcgctt tggtcgagac tatattgaaa ctggaaaata cctccagcga atttttcctg
    14641 ctatggggat ccgttttatc tcagttaatg accattatga tagcttgacg gctgatacca
    14701 atgaaactca tctggtcatg cccattaaaa gcctcattaa cgatagctat tgtcgggaca
    14761 tttcaactaa agtgcgaagt actcaaaaag ccaaacggca aaagggagag tttattgggg
    14821 cttttgctcc ttatggctat cgtaaagacc ataatcaacg aaaccattta gtggttgatg
    14881 aagcagttcg ctccactatc gaaacaatct ttgctctgaa attggaagga tattcttcta
    14941 atgccattgc gaattttttg aatcaagctg gggtggaaac acctctacaa cgtaagagag
    15001 cctgtcagga aaggattaaa ggcttctatg gttatcgtca taagtgggat accaaaatgg
    15061 tcaatcgtat cctgaccaat cgtgtctata ctggcacttt agaacaagga aaacagacca
    15121 aacttaatta taagtctcaa aagtctgtgg ctgtcaatcc agaagattgg gtacgagtgg
    15181 aagataccca cgaagccatt atctccacaa gtaccttttc tattgcgaat aacctcttac
    15241 tcagagatgt caaacatgga aagaatactc ctgacctctt tgcaggactc ttgttttgtg
    15301 gcgactgcca ggcacaactc ttgcagcgga aacttcgtta caaggacaaa gaaactgttc
    15361 agtatatttg tagcacctac aacaacggtc aaggctgtag tcgtcatgct attaaggaag
    15421 atgtgctaac cgatttagta tcaactatcg ttcatcagca tcttgattgg aagtcttatc
    15481 tagtaaaatc tattcctgat tatcttgacc aggaacactt tttagaggtt gattttactt
    15541 ctttgatttc ggagcgtcaa aagtatgagc agttgcttca gtccctgtat ctggatttag
    15601 atgacggatt aatcaatgaa acagaatacc aagagtttca gcgtagctat cgccaaaagc
    15661 taaagcaaat tgaagacact atcgttcaaa agaaagaatt ggctcaaacc ctctacgata
    15721 agctccagga taaggagact tggcttgagc agttgagcac gatacaacat gagcaagagc
    15781 ttaatcgtct cactctagtg actttactgg atcgtattat cgttcatgaa caacaagcat
    15841 taaccttgat gtttcacgat gtggcagaat tgtcccttct tcaacagttt tctaacatgg
    15901 aggtggtcta atggcacgta ctaagaaccg ctcccgtgta gaaacggtag aaaagatacc
    15961 tcttcaaacc tatcgaacag gtatttatat tcgattatcc aaagaacgta ccgaaagttg
    16021 gcgacataaa tcgcagtctt taaagaccca ggaaagtcta gctagaacct ttgcccaaga
    16081 aaaaggttta acagtcacca agtgctatat tgattatgaa tattctggca caaaatttaa
    16141 tcgcccagcc tatcaagata tgatggaaga catcaagaga ggtgtcatca attgtatctt
    16201 gattcgagac ttatcacgct tagggcgtaa ctacattgag attgggcgac tgattgataa
    16261 ggtatttccc tttatggggg ttcggtttat ttcaatcaat gataacctag atactctcaa
    16321 tgggctagaa gataagaaat cctttgaagt ggaaattaag aatttggtca atgaccttta
    16381 ttctaaggac atttcaaaga aagttatgtc ctataatatt caccaagcta gtcaaggata
    16441 ctatattgga acatctgctc cgtatggtta tcgaattgat cgccaagaag caggtgcgag
    16501 gttagttatt gataaccaag tcaagccaat tttagagttt atttttcaac aggcaattga
    16561 aggtgtatcc atatctcaga ttactactga attgaatcat agaggaattg ctgtacctca
    16621 gtcataccgt gggactggcc aattgtatag aagtgaacag gatatcaaaa gatggcatgc
    16681 aggaaatttg cttcgtctta tcaaaatgcc tgtttacagg ggagttctta ttcaacgaac
    16741 acggaacaaa tcgttatctg aagaggatta tatccatttt gaaaatgctc aagaagccta
    16801 tgtcagcaaa gataactacg aaaaaatact tttttatcta gatagtcgta agtccgttaa
    16861 aaagactagt atagtgagaa ctccaaaccg ctatagaggt ctggtttacg ccaaaacaaa
    16921 atcaactcaa atggttcgca gatgtcgcca tttctcaaac aataagtctg attatgatta
    16981 ctattatttt acggactata tctatgattc agagacaact gagagaaaaa ccgtctatat
    17041 cagtgaaaat gctctggaca agattatagt agagttgatc caatcagaaa tgaagcggtt
    17101 aggaacagtt gagacattgt tgccacggtt agaaactaaa aaagacgatt gcctaaagac
    17161 gtatcacaag caaataactt gtcatcaatg gaccatcaca cagctacaag ctgagctaag
    17221 tgacctttat gcgtctttta gtcttaatcg ttctgaacga gaagtctatc tctcccaaaa
    17281 gaacgagata atcgcaaaaa ttgaaaccat ttcacaagaa atagccttat gtgaaacctc
    17341 aataaagcag attgaggagg agcacagtaa gcaggtgaat tgggttagac atctagccaa
    17401 gagccaaaat caagttgttt taacggcaga actcttaaat gctttaatag aacggattga
    17461 ggttgatgta gacaaaacag tgacagtaac tttcagctgt cagattgggg gtggcgagca
    17521 tgactaaaat cgctctatat ctccgcttgt cagttgatga ggctgataca gatgaaagca
    17581 actcaattac gaaccaacgg tacttgttaa acaattatct cgaccaaaca cctgagttca
    17641 agaattggga acgcttggaa tttgtggacg atggtttttc aggaaccagt cttaaacgtc
    17701 cagcctttca acgcatgatg gccgatgtca aggctggaac tatccgtcat atcatcgtta
    17761 aagacttgtc acgatttatg agagactatc tggagttggg aaactactta gagaatatct
    17821 ttccttttct cggagttcga tttatcgctc tcaacgacca ttatgatagc ctggtgtctg
    17881 aacataatgg actggatatt gatgtgccct ttagaaactt actcaatgat ttctacgcca
    17941 aagacgtttc tgaaaaagtc aagagtgcaa tgaacagtat gaaacgctct gggaagaaca
    18001 tgagttggtt accaccgttt ggttatatca aggacccaaa tgaccgattt aagattatca
    18061 ttgatgagga agtcgctcca attgtgagac gaatttttag actttgcatt gagggaatgg
    18121 gaactcaaaa aatagcgatg ttacttaata gtgaacagac gattactcca gctgagagga
    18181 aaatgcaggt tagtcaagca aggtatacaa aatcaattat cattactgcc gaacaaaaga
    18241 ggaatgtatg gacgagaagt ggtattctcc aaatactcaa aaatgaagcc tataagggga
    18301 catacctgtt taacactaga acaacggtaa atggtaagca gattcggcgg cctgaatcag
    18361 agtgggaacg tcttgacaat aatcatgagg caattgtatc aagtgaggac tttgacaaag
    18421 ctcaacaatc acttacctct cgcattagtg ggacgaaaag tcaggtttgt aatcagccag
    18481 aagaagtttt attgagaggc ttagttatct gtgaacattg tgggcatcgt ctccttcgat
    18541 atagccacaa taacaacaat aattattttt attgttgtta ttgtagaagc caaggccaga
    18601 atatgaagtc ctgtcggata gatagaatag aagaggctat cgagaaagaa ttaaagtctc
    18661 ggttgccgat gaactctcca aagctatcaa aaacgaatct tataagagaa gttgaacggc
    18721 tgaaaactca aaaggtttct cattttcaag actataaaga gggcttgatg acaagagaaa
    18781 cttacatgga aaaacgtcag aacttagata attctataat ggaaatagaa gaacaattaa
    18841 aggtagttgg tagggaaaat atagcatttg acaagaaatt gaccagagaa gtagttgaca
    18901 ctcatatcga gaggattgtc gtcaatggcc aaggttcttt tacagtcgtc tataaataac
    18961 ctaatgagag acttgtgtaa tagcaagtct ctttcttgaa aagtagcttt gtggtataat
    19021 aagggtgttt tcagtgtaga aaaatagtgt catttacttg acataagagg ggtggagtga
    19081 aatatgggaa aattctagga ccatggggcg ctgcaatagg aggagcagtg gtttgtggat
    19141 atttagccta taccgctaca tcataaaaat gaaagctaaa ttttatgaag gctatattct
    19201 ttattattct cttcgctttt caaacctatc ttatttatct atccataagt atctctgata
    19261 aaaaacaaaa gactattgaa ttaacatcat tgaattgttt tgtcatatta tttctaatct
    19321 atgataaatt aatttttctc tttattgcct atgttttttt gataattttt atattaaact
    19381 tgttccgtaa ctgaaaagtg acatactata tgaatacaaa aatgatgtca caattttctg
    19441 ttatggataa tgaaatgctt gcttgcgttg aaggtggaga tattgattgg ggaagaaaaa
    19501 ttagttgtgc agcaggggtt gcatatggcg caattgatgg gtgtgtaaca acggtttgac
    19561 atttctattg ggaccatttg ctataggaat aggtgtaact ggtgctgcag gtggagctat
    19621 acttggaggt gtagcctatg cagcaacatg ttggtggtaa ttatggattt taaaagtttt
    19681 attattggtt tagtagttgg tatatttggt ccttatatgg atgatttaat tagaaaaata
    19741 ttttcaaaat ctcccaaaaa ggatacagat agtaccccct aaaaaataaa tttctcccct
    19801 gtatttgcta gcttaattta caggggagtt tctttaattt tgtttcgcct gtcaaaatga
    19861 tatgtgatag caggatgaaa agtctacaaa caagttggta tcaatacaat ataaagagga
    19921 aagtatgttt ttcatgcttg ctttttttaa tttttacaat tcaagaggtt ttgatgacca
    19981 tttatgattt gagtgatcca aggtcaaaat aagtgctata ctagcagtgt aaatgttctt
    20041 gctcaactaa gataaagcac acatttagga ggaaatctta tgaagaaaaa aatactgatt
    20101 attttcgttc tgtatctaat catgtccatc tttctatatc cgcttaggga gagtgcttgg
    20161 tatcagctat tttataccat agcctatgtg attgcagtta tgatctattt tgctatcaat
    20221 aaaaagaaag gagaaaagaa atgaaaattt ttcttgctaa aaaacggaac atcttccttg
    20281 cgagattgtt cttaggtcag ttgcccttgc ttgtctctac ttatctattt ctatctcgtc
    20341 agtttttaaa tttttcctta gttttccaat tttttttagt ggttattaac ttagcttcta
    20401 ttttggtcac tgtttacctc actagggaaa tgcggataaa agagtttgaa gacgatgatt
    20461 tggttagtcc tagaactaat caactcatgt tcatcggctt gacaggtttt atgtctatta
    20521 tttgtttgta tagagggatc acagcaggag aatcctacca acaaataatt gcctacattg
    20581 gcgctattct ctgcttgacc atcatgcttc tgctcatttg gggattgaag tattataaaa
    20641 agtagagctt aataaagtat aaaggggtaa gtgtttttga aatacttacc cttttataat
    20701 gaagtttttg caattcaaga tgtttcgatg accatttaag atttagatga atttgtaatc
    20761 ttaaataagg taagataaag ataacaaatg taaaggagta ttcttatgaa gaaacaaaag
    20821 ataaaatcgc tattacttgt accacttgta tttgcatcta ttactgcagg tcttgcatat
    20881 gcagaagaac agcctactac ttcatctacc caggcgaatg atagttctct tgtggcgcca
    20941 gatttgccat cggctaagga aaaggtggag cataagcctt ctgttgtaac cccagaagag
    21001 tatgagaaga atgttacgga ctttaaaaag atagatattg aagctgttcg tcaatctttt
    21061 acaggggatc aattggaaca tactatttat tttggtagaa aaacttgctc tcattgtcgt
    21121 caattttctc ctgaattgaa agaatttaat aacttgattg aaaagaagtt agagtattat
    21181 gatttggatg gtaaggattt tgatggggaa gcgagagagt ttctatttta aaaaagtcgg
    21241 tattccagga acaccaacaa ttttgtattt aagaaatgga catccgacat ctggatgggt
    21301 tggtggcgga gcaactgcac aacaggtgta tgattatatg tattcgagaa actcacctaa
    21361 gcaaacggag acagtgaaat cttctgagga aacagtaact gaaagtgtcc gtgatgagaa
    21421 tactagaagt gacagcatga atattagtga taaagttgta agtgacagca aaggtatgag
    21481 tgataaaaaa agaactgaaa tgaaaatatc caatgctaat agtgaaaata gtgggaaagt
    21541 ggagagtaca aactcaactt ctgaagctaa aactactcaa tctggcaatt tagcaatgtt
    21601 agacaataag aatcaattgg aaactctcaa acctattttt gatgctgctc aagaaaataa
    21661 aacttcttta actgatgtta aggatgctga ttatgtaagc gaatctatta cttcgaatga
    21721 aaaattatta ctgaaaacag gcgaggaaga aagttaccaa ctgattcgac tagctgtcgc
    21781 gttttttatg gcttctataa tgattaaagt gaaacaaaaa attcataaat aaaaatagat
    21841 ggtaaacagg tgaaatgata ctatttgttt gtaataacat atagctagaa tttgcctata
    21901 gacaagagtg aaagggcaag tatgttgtta atgcttgctt tttaaatttt ttaacaattc
    21961 aagacgtttc gatgacaatt caagatttgg atgaaaaaaa ttaataaacg atgatatact
    22021 aaacttgtca aggttgcaac aggacaaaaa ttaaacataa aaaaggagat attcgtcatg
    22081 gatacaaaaa tgatgtcaca atttgcagtt atggataatg aaatgcttgc tcgtatagag
    22141 ggtggggatg tctctgatat ttatagaggg tacgctaatc aggtaagtcc attcggttct
    22201 taccctccta tattaaaaaa ttcaggtcct tttccagtaa gtggttactg cccgcgcggt
    22261 tatcatgacc gtggttatat aggagcaggt tttcatttat gtggaatata ggctgaaata
    22321 caagaaatga ggaagaattt ctatgaaaaa gtatcagctt gttttcaaaa taagtgcagt
    22381 cttgtcttac ctatttttcg tatttggtct ttctcagtta actcttatcg tccaaaatca
    22441 ttggcaattt tcttctcagg taggaaattt tttctggatt agaaatatct tgagtctgct
    22501 atttagcgga gtcatgattt ggattctggt taagacaggc catggctatc tctttcgcat
    22561 tccaagaaaa aaatggcttt ggtattctat tttgacagta ttagtggtag tgctccatat
    22621 ctcttttaac gttcagacag ctaaacatgt tcagtcaacc gctgaaggtt gggccgtatt
    22681 gatcggttat agtgggacca actttgctga gctaggtatc tatgtaaccc tgtttttcct
    22741 gactccacta atggaagagt tgatttatag gggattactg caacacgcct tctttaagca
    22801 ttcgcgattt ggccttgatt tgcttcttcc ttccattttg tttgctcttc ctcatttttt
    22861 gagtctgcct agtctgttag atatcttcgt ctttgcaaca tttggaatca tctttgccgg
    22921 tttgacccgc tataccaaga gtatttatcc atcctatgcg gtgcatgtga tcaataatat
    22981 tgtagcgacc ttcccgtttt tgctcacttt tctacatagg gtcttggggt aaaaaaaaca
    23041 aaaggcttgc ttttcagcca tagaggaggt catcatgtat aaacacttat ttttcctaga
    23101 ttccaaaact ttagatcggt tgacacccta tattatagtc ttggcttctg acaccattgc
    23161 ttttaatgtt tttgtgctaa cctttgtatc tgcggtggtt tttaatttcc taaattccat
    23221 gctagcttta atggctatat tcataggggc tggctatgtg gtcggatttt ggttgctaaa
    23281 atggtttgtt ttggaaaggc tagatctaaa gaatgacgtg taggaagtct gtttgttgag
    23341 gaggataatt ttatggagtt ttttgataaa tttcatgcct tgtgttttgg atttttagta
    23401 ctaataattg tcattacagt tccttatacg attaaccatg gggatttttt tcaaaatgaa
    23461 tctgcattga ttattgtaag tcttcttgta acctcgctga gtgttgctta tgctagaaag
    23521 tttgaaatga tttcttttgg gatgttaagc aagaaacaac ttttgctttt cattgcaatc
    23581 tttcttctaa gtgtacttga gacgctggtt tatattcatt tcttcgctgt ttcttctggc
    23641 tcaggggtcc aacacttggc ggaagtcagc agaggaattt ccctgtcttt gattttgact
    23701 acctcagttt ttggccccat ccaggaggaa ctcattttca gaggacttct tcaaggtgcg
    23761 gtttttgaca attcttggtt agggcttgtg ctaacttcct ctctcttttc tttcatgcat
    23821 ggaccttcta atgtcccttc gtttattttt tatctacttg ggggtttgtt gctgggcttt
    23881 gcttataaaa agagccaaaa cctatgggtt tctactctag tccatatgct ttacaacagt
    23941 tggccactct tatattattt ataaaaatca tgaaaaggta agtaggagat tgtgcttacc
    24001 tttttctttc tataatgata acccaaacca ctccagaggc ttttctttga gaatcgggtt
    24061 agagtggttg acgaataggc caaaaactag tagaatagta aggaaacttt atacggagga
    24121 aagaaatgga tttgggtgat aatgagctaa cactgactcc catacctggg aaaagtggca
    24181 aggcttatat gggtagctat cctgatggga agcgcatctt tgtaaaaatg aacacctctc
    24241 caatcctacc tggtctagct agagaacaaa ttgctccaca attattatgg agtcgtcgtt
    24301 tggcagatgg gcgtgatatg tgtgctcaag aatggttgac aggcaagata ttgaccccct
    24361 atgatatgaa tcgtaagcaa atcgtcaata ttttaacccg tcttcatcgc tcacgtccgt
    24421 tgatgacaca attgagtcgt ttgggctatg ccatggaaac acctgtagat ttactacagt
    24481 cttggcagga aacggctcca gatgctttgc gtaaaaatca ttttatcagt gaagtgatgg
    24541 ctgatttacg tcagactatt ccaggattta gagaggacca tgcgaccatt gtccatggag
    24601 atgtacgaca tagtaattgg attgagacag atagtggctt gatttattta gtagattggg
    24661 attcggttcg cttgaccgat cgcatgtttg atgtggccca tatgctctgc cattatattt
    24721 cagaacatca gtggaaggaa tggttgacct actacggtta caagtacaat caaacggtat
    24781 taagtaaatt gtattggtat ggtcaattgt cttatttgag tcagatttcc aagtattata
    24841 tgaaccaaga tttagaaaat gtcaatcggg agattcatgg tttgcgtcat ttccgagaca
    24901 agtatggaaa gagaagatga gagttagaaa tcgtaaaggg gcaacagaat tactagaggc
    24961 aaatccccag tatgtggtcc tcaatccctt ggaagccaag gcaaaatggc gggacttgtt
    25021 tggcaatgat aatcccattc atgtggaagt tggaagtgga aagggtgcct ttgtttcagg
    25081 tatggccaag caaaaccctg acatcaacta tatcgggatt gatattcaaa agtctgtttt
    25141 gagctacgct ttggacaagg tgcttgaagt tggagtgcct aacatcaagc tcttgtgggt
    25201 agatggttct gacttaactg actactttga agacggtgag attgatcgct tgtatctgaa
    25261 cttttcagat ccatggccga aaaaacgcca tgaaaagcgt cgtttgacct acaagacctt
    25321 cttggatacc ttcaaacgta tcttgcctga aaatggagaa attcatttca agacggataa
    25381 ccgtggcttg tttgagtaca gtttagtgag cttttctcaa tatggcatga aactcaatgg
    25441 tgtctggtta gatttgcatg ccagtgattt tgaaggcaat gtcatgacag aatacgagca
    25501 aaaattctca aacaaggggc aagttatcta ccgagttgag gcagaatttt aagagatagc
    25561 ctaaaattag gctgtacaag tgcttttgct ttacataagt tggcaaacgt gctatactga
    25621 tagtaagaat atgaaaagtg aggcggggaa atatcttcgc ctcttgctta tgaggaggtg
    25681 gacgcaatcg caacaatcgt agaattagtc agagaagttg tagaacctgt catagaagct
    25741 ccttttgaac tcgtggatat cgagtatgga aagattggca gtgacatgat tctcagtatt
    25801 tttgtagata aacccgaagg aattaccttg aacgacacgg cagacttgac agaaatgatc
    25861 agtcctgtcc tagacaccat caagccagat cccttcccag aacaatattt cctagaaatt
    25921 accagtccag gtttggaacg tcctttgaaa accaaggatg ccgtcgctgg agcggttgga
    25981 aaatacatcc atgtcgggct ctaccaagcc atcgataagc aaaaggtctt tgaaggaacc
    26041 ttgttggcct tcgaagagga cgagttgact atggaatata tggacaagac gcgtaagaaa
    26101 accgtccaaa ttccatacag tttagtatca aaagcacgtt tagcagttaa attatagaaa
    26161 aagaaaggat agcttttgag gattcaaaag tgaagaaaac atgagtaaag aaatgctaga
    26221 ggccttccgc attttggaag aagacaaggg aatcaaaaaa gaagatatca tcgacgcagt
    26281 agtagagtcg cttcgttccg cttatcgcag acgctatggt cagtcagaca gcgtagctat
    26341 tgacttcaac gaaaaaacag gtgactttac agtttatact gtccgtgaag ttgttgatga
    26401 agtatttgat agccgtttgg aaatcagctt gaaagatgct cttgccatta attcagctta
    26461 tgaacttgga gacaaaatca agtttgaaga agcaccagct gagtttggtc gtgtagcagc
    26521 ccaatctgcc aaacaaacca tcatggaaaa aatgcgcaag caaacacgtg ccatcactta
    26581 caatacttac aaagaacatg agcaagaaat catgtctggt acagtagaac gctttgacaa
    26641 ccgctttatc tatgtcaacc ttggtagcat cgaagcccaa ttgtcaaaac aagaccaaat
    26701 tcctggagaa gtttttgctt ctcatgatcg tatcgaagtt tatgtttaca aggttgaaga
    26761 caaccctcgt ggtgtgaacg tctttgttag ccgtagccat ccagaaatga tcaaacgttt
    26821 gatggagcaa gaaattccag aagtttatga tggaactgtt gaaatcatga gcgtggctcg
    26881 tgaagcaggt gaccgtacga aggttgctgt tcgtagccac aatccaaacg tggatgctat
    26941 cggtacaatc gttggacgtg gtggtgctaa tatcaagaag attactagca aattccaccc
    27001 agctcgttac gatgctaaaa atgaccgcat ggtaccaatc gaagaaaata tcgatgttat
    27061 cgagtgggta gcagatccag ctgaatttat ctacaatgcc atcgctcctg ctgaggttga
    27121 ccaagttatc tttgatgaaa acgacagcaa acgtgccttg gtggttgttc cagataacaa
    27181 gctttctctt gccattggtc gtcgtggaca aaacgtgcgc ttggcggctc acttgactgg
    27241 ttaccgtatc gatatcaagt ctgctagcga atttgaagcc atggaagacg ctgcttcagt
    27301 agagttggaa gtagaaaacg atactgtaga agaataaaag ctgctagagg agggaaagat
    27361 gaaaacaaga aaaatccctt tgcgcaagtc tgttgtgtct aacgaagtga ttgataagcg
    27421 tgatttgctc cgcattgtca agaacaagga aggacaagtc tttattgatc ctacgggcaa
    27481 ggccaatggc cgcggcgctt atatcaaact agacaatgca gaagccctag aggcgaaaaa
    27541 gaagaaggtc tttaaccgca gctttagcat ggaagtggaa gaaagctttt atgacgagtt
    27601 gatcgcttat gtggatcaca aagtgaaaag aagagagttg ggacttgaat aagcaaaaga
    27661 taagtaatct cttggggctt gctcagcgag cagggcgcat catatcgggt gaagaattgg
    27721 tggtcaaggc cattcaagac ggcaaggcca agttggtctt tctagctcat gatgctggac
    27781 ccaatctgac caagaagatt caagataaaa gtcattatta tcaagtagaa attgtaaccg
    27841 tgttttcaac actggaatta agcatagcag tcgggaaatc gagaaaggtt ttggctgtaa
    27901 cagatgctgg atttacaaag aaaatgaggt ctcttatgga atagaagagg aggacatgat
    27961 ttgtctaaga aaagattgta cgaaatcgca aaagaacttg gaaaagaaag taaagaagtt
    28021 gtagcgcgtg caaaagagtt gggcttggat gtgaaaagcc actcatcaag tgtggaagaa
    28081 gctgtcgctg caaaaattgc tgccagcttt aagtctgcag ctgctccgaa agtagaagca
    28141 aaacctgcag caccaaaagt aagtgcagaa aagaaagccg aaaaatctga gccagctaaa
    28201 ccagctgtag ctaaggaaga ggcaaaaccg gctgagccag ttgctccgaa aacagaaaaa
    28261 gtagcagcga aaccgcaaag tcgtaatttc aaggctgagc gtgaagcccg tgctaaagag
    28321 caggcagaac gacgcaagca aaataagggc aataaccgtg accaacaaca aaacggaaac
    28381 cgtcagaaaa acgacggccg taatggtgga aaacaaggtc aaagcaaccg cgacaatcgt
    28441 cgctttaatg accaagctaa gaagcagcaa ggtcagcaaa aacgtagaaa tgagcgccgt
    28501 cagcaagagg acaaacgttc aaatcaagtg gctccacgta ttgactttaa agcccgtgca
    28561 gcagccctaa aagcagagca aaatgcagag tacgctcgtt caagtgagga acgcttcaag
    28621 cagtatcagg ctgctaaaga agccttggct caagctaaca aacgcaagga accagaggaa
    28681 atctttgaag aagcggctaa gttagctgaa caagcacagc aagttcaagc agtggttgaa
    28741 gtcgtccctg agaaaaaaga acctgcagtg gatacacgtc gtaaaaaaca agctcgacca
    28801 gacaaaaatc gtgacgatta tgatcatgaa gaagatggtc ctagaaaaca acaaaagaat
    28861 cgaagtagtc aaaatcaagt gagaaatcaa aagaatagta actggaataa caacaaaaag
    28921 aacaaaaaag gcaataacaa gaacaaccgt aatcagactc caaaacctgt tacggagcgt
    28981 aaattccatg aattgccaac agaatttgaa tatacagatg gtatgaccgt tgcggaaatc
    29041 gcaaaacgta tcaaacgtga accagctgaa atcgttaaga aacttttcat gatgggtgtc
    29101 atggccacac aaaaccaatc cttggatggg gaaacaattg aactcctcat ggtggattac
    29161 ggtatcgaag ctaaacaaaa ggttgaagtg gataatgctg acatcgaacg tttctttgtc
    29221 gaagatggtt atctcaatga agatgaattg gttgagcgtc caccagttgt tactatcatg
    29281 ggacacgttg accacggtaa aacaaccctt ttggatactc ttcgtaactc acgtgttgcg
    29341 acaggtgaag caggtggtat tactcagcat atcggtgcct accaaatcgt ggaaaatggt
    29401 aagaagatta ccttccttga tacaccagga cacgcggcct ttacatcaat gcgtgcgcgt
    29461 ggtgcttctg ttaccgatat tacgatcttg gtcgtagcgg cagatgacgg ggttatgcct
    29521 cagactatcg aagccattaa ccactcaaaa gcggccaacg ttccaatcat cgtagccatt
    29581 aacaagattg ataaaccagg tgctaaccca gaacgcgtta tcggtgaatt ggcagagcat
    29641 ggagttatgt caactgcttg gggtggagat tctgaatttg ttgaaatctc agctaaattc
    29701 aaccaaaata tcgaagaatt gttggaaaca gtccttcttg tagctgaaat ccaagaactc
    29761 aaggcagacc caacagtgcg tgcaatcggt acggttatcg aagcgcgctt ggataaagga
    29821 aaaggtgcgg tcgcaaccct tcttgtacaa caaggtacct tgaatgttca agacccaatc
    29881 gttgtcggaa ataccttcgg tcgtgtccgt gctatgacca acgaccttgg tcgtcgtgtt
    29941 aaagttgctg gaccatcaac accagtctct atcacaggtt tgaacgaagc accgatggcg
    30001 ggtgaccact ttgccgttta cgaggatgaa aaatctgcgc gtgcagcagg tgaagagcgt
    30061 gccaaacgtg ccctcatgaa acaacgtcaa gctacccaac gtgttagcct tgaaaacctc
    30121 tttgataccc ttaaagctgg ggaactcaaa tctgttaatg ttatcatcaa ggccgatgta
    30181 caaggttctg ttgaagcact ttctgcctca cttcaaaaga ttgacgtgga aggtgtcaaa
    30241 gtgactatcg tccactcagc ggtcggtgct atcaacgaat cagacgtgac ccttgccgaa
    30301 gcttcaaatg cctttatcgt tggtttcaac gtacgcccta caccacaagc tcgtcaacaa
    30361 gcagaagctg acgatgtgga aatccgtctt cacagcatta tctacaaggt tatcgaagag
    30421 atggaagaag ctatgaaagg gatgcttgat ccagaatttg aagaaaaagt tattggtgaa
    30481 gcggttatcc gtgaaacctt caaggtgtct aaagtgggaa ctatcggtgg atttatggtt
    30541 atcaacggta aggttgcccg tgactctaaa gtccgtgtta tccgtgatgg tgtcgttatc
    30601 tatgatggtg aactcgcaag cttgaaacac tataaagacg acgttaagga agttacaaac
    30661 ggccgtgaag gtggattgat gatcgacggc tacaatgata ttaagatgga tgatgtgatt
    30721 gaggcgtatg tcatggaaga aatcaagaga taagattttt tgctcctttc ttaggtggtg
    30781 agggacgcaa gcaaaccgat ggtttcattg cttatttttg agcctagggt ctcaaaaatc
    30841 ccctgtgatg ggactgataa atcagttcca tcactttcac cacggcgaaa gaagcagatg
    30901 acttcaaatt gaacttcgtt tcaatttaaa ctgaaaatca agaagtttaa aatagctagg
    30961 tctgctggcc tagcttttgg ttcaaagtag agaaaggaat atcatggcaa atcatttccg
    31021 tacagatcgt gtgggcatgg aaatcaagcg tgaagtcaat gagattttgc aaaagaaagt
    31081 ccgtgatcca cgtgtccaag gtgtgaccat cacagatgtt cagatgctgg gtgacttgtc
    31141 tgttgccaag gtttattaca ccattttgag taaccttgct tcggataacc aaaaagccca
    31201 aatcgggctt gaaaaagcaa ttggtaccat caaacgtgaa cttggtcgca atttgaaatt
    31261 gtacaaaatc ccagatttga ccttcgtcaa agacgagtcc atcgagtatg gaaacaagat
    31321 tgacgagatg ctacgcaatc tggataagaa ctaaagaaga ggggttgccc ctcttttttg
    31381 gtggaggaaa ataggttgaa tttgaaatgg aaaaatattc ttttaaaata tattgaaact
    31441 agaatagtac gcctctactt ctaaaacatt gttagaaatc gatttgactg tcctgatcga
    31501 tttgtcctgt tcttgtttta ttttactata aaaaaggggt tctgtatttt ttaatgttat
    31561 ctaattagaa aatgcttttt ttgtaggaaa tataatatga taaggtgcaa aaaagaaata
    31621 aggagtttgt atatggctga acaagactta gctatgcaag tattacaaca agtggtaaaa
    31681 ctaccagttg ttaaggttga tcgttcgaaa tttttagtgg ataagttttc caaagaattg
    31741 ggtccacagg acattcctac cttattggaa caaggtccaa cgtctctctt atctcaagaa
    31801 atcttagatc gagtggctaa tgcctgtatt agggataatg ttttattagc gagtgggact
    31861 tctgttttgg caggattacc tggagggctt gctatggcaa ttaccattcc agcttatgtg
    31921 gctcaatttt atggtttctc tctgaaattg gcccaagaat taggttatat ttatggttat
    31981 gaggatcttt gggcttcacg tgaggagttg agtgaagata ctcaaaatac cctcttgctt
    32041 tatctaggcg taatgttagg ggtgaatgga accgctgctt tgtttgctac gtgctggtgg
    32101 tataacaatt gccaaacagg taatgaaaac agtgcctaat aaagctttaa caaagacgct
    32161 ttggtaccct attttgaaaa aagtcttaag aatatttggt gtgaatctta ccaagggagg
    32221 gctggccaaa ggaataggga aatttattcc tatcttgggt ggtatcattt caggtggttt
    32281 aacctttgca actatgaaac caatggggga aagcttgcag aaagaattat ccaagctagt
    32341 caactatagt gaagttcaat atcaagaaga tgttgaaaca atccgaaaag aggctgaaat
    32401 catcaaagga gagtaatatg aatcctatca aagcttttgc taaaatttat ggtaattact
    32461 ttttgaccgt gcaaggtgta aaagtgatga aaacgataaa gaaagctgac catgtcgttg
    32521 ttggtctggg caaacttttt attgcagata agctaatgga tacggctcgg tggctcatta
    32581 agccagagga gagagaatga aatttttttg gtcttcttgc tattcttttt atcaaaccga
    32641 ttattgggat tgtgaaattc ttttggatga tcatttcttt tgcagttcaa ttgctgtttt
    32701 acaagatatt atttaagata ttggattggc tctttaaact tatctagatg gtaatccaag
    32761 tcgcagagag ctagcaggaa ctccactgct agttttttaa tctctctcca tatggtataa
    32821 tataagcagt aaaatcattt tatactcttc gaaaatctct tcaaaccacg tcagcttcac
    32881 cttgcagtat atatgttact gacttcgtca gttctatcca caacctcaaa acggtgtttt
    32941 gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta ttagaacata
    33001 taatggaggt cgtcatggac aatatcatcg atgtgtcaat tcctgttgca gaagtggtgg
    33061 acaagcatcc agaagtcttg gaaattctag tggagctggg ttttaaaccc cttgccaatc
    33121 ccttaatgcg caatacagtt ggtcgtaaag tatcacttaa acagggttct aagctagcag
    33181 gaactcctat ggacaagatt gtacgcacac tggaagcgaa tggctacgaa gtgattggat
    33241 tagactaatg acagatgaac ggattcatgt cctacgggat attttattag aattgcataa
    33301 tggcgcctct cctgagtcgg ttcaggagcg ttttgatgcg acctttgcgg gtgtctcagc
    33361 cattgagatt tcccttatgg agcacgagct gatgaactca gactcaggtg tcacctttga
    33421 agatgttatg gaactctgtg atgtccatgc caatcttttt aaaaatgcta tcaaaggtgt
    33481 cgaagtttca gatactgagc atccaggtca cccagttcgt gtcttcaaag aagaaaatct
    33541 ggctctccgt gcggccttga ttcgcattcg tagattgtta gatacctatg agtctatgga
    33601 agacgaggaa atgcttgcgg agatgcgcaa gggcttggtg cgtcagatgg ggcttgtggg
    33661 gcaatttgac atccattacc aacgtaagga agaactcttc tttcctatca tggagcgcta
    33721 tggacacgat tcacctccca aagttatgtg gggagtggat gatcagatta gggaactctt
    33781 tcaaacagct ctaacgacag ccaagtcact accagaagtg tcaattagca gtgtaaagga
    33841 agcttttgaa gcttttgcga cagagtttga aagtatgatt ttcaaggaag agtccatcct
    33901 cctcatgatt ctccttgagt cttttactca ggatgactgg cttcagattg cggaggagag
    33961 cgatgcctat ggctatgcca tcatccgtcc gtcagagaaa tgggtgccag aacgacagag
    34021 ctttattgag gaaaagattg cagaggaacc tgtacagcta gatacggcag aaggtcaagt
    34081 tcaacaagtc atagatacgc cagaaggcca ttttaccatt acctttaccc ctaaggaaaa
    34141 ggaagctgtg ctggaccgcc atagtcaaca ggcttttggt aatggctatc tttcagtcga
    34201 gcaggccaat ctcatcctca atcatctccc tatggagatt acctttgtca ataaagaaga
    34261 tattttccag tattacaatg acaatacgcc agctgatgag atgattttca aacggacgcc
    34321 gtcccaagtc gggcgcaatg tcgaactctg ccatccgcct aagtacttgg acaaggtcaa
    34381 aactatcatg aaggggcttc gtgagggaag caaagacaag tatgaaatgt ggttcaagtc
    34441 tgagtcgcga ggtaagtttg tccacatcac ctatgctgca gtacacgatg aagacggaga
    34501 attccaagga gtgttggagt atgttcagga tatccagccc taccgtgaga ttgatacgga
    34561 ctattttcgt ggattagaat aaggagaaaa aatgagttac gaacaagaat ttatgaagga
    34621 atttgaagct tgggtcaata cccaaatcat gattaacgat atggcgcaca aggaaagtca
    34681 aaaagtttac gaagaagacc aggacgagcg tgccaaagat gccatgattc gctacgagag
    34741 tcgcttggat gcttatcagt tcttgcttgg taagtttgaa aacttcaaag caggcaaggg
    34801 attccatgat ttgccagaag gcttgtttgg tgagcgaaat tattaaacga gaaagattct
    34861 tgatttttca ctaaaatctt gatagaatgt ttatgttaaa tccttgtcag agcagggatt
    34921 ttttattgaa aggattttat catgtcaaag aaactcaatc gtaaaaaaca attacgaaat
    34981 ggcctccgtc gcgcaggtgc cttttcaagt actgtgacta aggttgtaga tgagacaaaa
    35041 aaagtcgtga agcgtgcaga acagtcagca agcgcagctg gtaaggctgt ttctaaaaaa
    35101 gttgaacaag cagtagaagc taccaaagag caagctcaaa aagtagctaa ttctgtagaa
    35161 gattttgcag caaatttggg tggacttcca cttgatcgtg ccaagacttt ctatgatgaa
    35221 ggaatcaagt ctgcttcaga tttcaaaaac tggactgaaa aagaactcct tgccttgaaa
    35281 ggaatcggcc cagctaccat caagaaattg aaagaaaatg gcatcaagtt caagtaattt
    35341 ttcttgagcc ttgcatttcc gaaaaaatct tgctacaata gagccattag aggtgttttg
    35401 aatcccacat tttacagaaa gtggcggcgc tgagaagtcc acaaatgtgt caaaactggt
    35461 tgctaatgga tgaaaaattg aaataaaagt gtctttttgc tttaaagacg agagttgcgg
    35521 gcaactgccc gaaattgggt ggtaccgcgg ataaacacat tcgtccctgt catgtagatg
    35581 gcagggcttt tcttttacgt cttagtcaaa gggggttgtt atgaagcaat cttttaacac
    35641 aagtaaacta tattatggtt ttcctgtttt tattttagga tatcaagatt agaattttgg
    35701 ctataacatc acgacctgta gttcctctta tagtctagga gattgggttg tgattggagt
    35761 cgttgcgaga gagaatgccg cagagcagat caaacagtat caaaaattta ctgtgaatat
    35821 ttctgatgaa acttctatgc ttgcgatgga gcaggctggt tttatcagtc atcaggagaa
    35881 attggaacgt ttgggagtgc attatgaaat ttctgaacga actcagactc ctattttaga
    35941 cgcctgtcca cttgttttag attgtcgggt agataggatt gttgaggaag acggtatttg
    36001 ccacatcttt gccaagattc ttgagcgact tgttgttcca gaactcctgg atgaaaaggg
    36061 acattttaaa aatcaactgt ttgccccaac ctatttcatg ggagatggat atcagcgcgt
    36121 ttatcgctat ctggacaagc gtgtagatat gaagggcagt ttcatcaaaa aagcgaggaa
    36181 gaaggatggc aagaactgag ctgccagata aaatcgaaac agaacgtctc gttttacgag
    36241 tccgtactgt ggcggatgct gaggatatct ttgactatgc tagtttgcca gaggttgcct
    36301 atccagcagg ttttcctcca gtcaagacct tggaagatga gatttattat ctggagcaca
    36361 ttcttccgga gcgtaatcaa aaggaaaatc tcccagcagg ctacgggatt gtcgtcaaag
    36421 gaacggataa gatcgttggc tctgtcgatt tcaaccatcg ccatgaagat gatgtgctgg
    36481 aaatcggcta taccttacac ccagactatt gggggcgagg ttatgttcca gaagcagcgt
    36541 gtgccttgat tgatctagct tttaaagaac ttggtcttca caagattgaa ctaacttgct
    36601 ttggatataa ccttcaaagt caacgagtct cggaaaagct tggctttacc ctcgaagctc
    36661 gcataagaga ccgcaaagat gctcaaggca actgctgtga tgatttgaga tatggcttgc
    36721 tgaggagtga gtgggaggtg atttgatgca tcttttcatc attggtgctc cagcatcagg
    36781 aaaaatgacc attggtcaag aattatctcg actgacggat gctaccctat tttataacca
    36841 tcaagccatt gattttgcac tagagatcta tcaggattat accgaggaga tgtgggaatt
    36901 tgttcgtgga attacctttt ctttccttgg agcaagtgca agaaatcagc gatcagtaat
    36961 tttaacagac gtaattgatt tttcaaatca gtaccagctg atgtatttaa agcaaattca
    37021 ggatttattg gataactttc atcaagagat tctgtttgtt gaattggaaa caagtcttga
    37081 agagtgcata cgtcgaaatc gaacggagaa tcgattaaag cacaaaccct taaaacgaca
    37141 tattgaggta tctgaaagag aaattttaga gaccgctgaa acacttcaat taaattccca
    37201 acatcaaccg aatgagttgc accactactt taaaataaat aatacgaatt tgtctgcaga
    37261 agaagctgct aagcaaattc aaaataaaat aaacaaaata gagaaaggac acacacatgt
    37321 ctaaagaact ttcacctaaa tacaatccag ccgaggttga ggctggtcgt taccaaaaat
    37381 ggcttgatgc ggatgttttc aagccttcag gcgatcaaaa ggctaagcct tattcaatcg
    37441 tgattccacc accaaacgta actgggaaac ttcaccttgg tcacgcttgg gatacgactt
    37501 tgcaggatat catcatccgt caaaaacgca tgcaaggctt tgataccctt tggcttccag
    37561 gtatggacca cgctggtatt gcgactcagg ctaaggttga ggagcgctta cgtggtgagg
    37621 gtattacgcg ttatgaccta ggtcgtgagt ctttcttgac gaaggtctgg gaatggaaag
    37681 acgaatatgc cactaccatc aaggaacaat ggggcaagat ggggctttct gtagactatt
    37741 ctcgtgagcg tttcactctt gatgaaggtt tgtcaaaagc tgttcgtaag gtctttgtgg
    37801 atctttacaa gaaaggctgg atctatcgtg gtgagtttat catcaactgg gacccagcag
    37861 ctcgcacagc cctttctgat attgaggtga ttcacaagga tgtagaaggt gccttctacc
    37921 acatgaatta catgctggaa gatggttcac gcgcccttga agttgctaca actcgtcctg
    37981 agactatgtt tggggacgtt gcggttgcgg ttaatccaga agacccgcgc tacaaggact
    38041 tgattggtaa aaacgtcatc cttccaatcg ctaataaact catcccaatc gttggagatg
    38101 agcacgcaga tcctgagctt ggtacaggtg tcgtgaaaat cacacctgcc cacgatccaa
    38161 atgacttctt ggttggccaa cgtcataact tgccacaagt caacgtcatg aacgacgacg
    38221 gaactatgaa tgagcttgcc tttgaatttt caggcatgga tcgttttgaa gctcgtaagg
    38281 cagtcgttgc taagttggaa gaaatcggtg cccttgtcaa aatcgaaaaa cgtgtccaca
    38341 gtgttggtca ctcagaacgt acaggtgtcg tagttgagcc acgcttgtct actcaatggt
    38401 tcgtcaagat ggaccaattg gctaagaacg ccattgccaa ccaagacaca gaggacaagg
    38461 tcgaattcta cccacctcgt ttcaacgata ccttccttca atggatggaa aatgtccacg
    38521 actgggttat ctctcgtcag ctttggtggg gtcaccaaat ccctgcctgg tacaatgctg
    38581 atggtgaaat gtatgtcggc gaagaagctc cagaaggtga cggatggact caggacgaag
    38641 acgtcttgga tacttggttc agttctgccc tctggccatt ttcaaccatg ggctggcctg
    38701 aagtcgactc agaagacttt aaacgttatt tcccaacttc aaccttggta acaggttacg
    38761 acatcatctt cttctgggtg tctcgtatga tcttccagtc cttggaattt actggtcgtc
    38821 agccattcca aaacgtgctt atccacggtc tcatccgtga cgagcaagga cgcaagatgt
    38881 ctaaatctct cggtaacggg attgacccaa tggatgtcat cgagaaatac ggtgctgatg
    38941 cccttcgttg gttcctttca aacggttccg caccaggtca agacgttcgt ttctcttacg
    39001 agaaaatgga tgcttcatgg aactttatta acaaaatttg gaacatttct cgctatatcc
    39061 tcatgaacaa tgaaggtttg acgctggatg tggcgcatga caatgtcaca aaagttgcaa
    39121 caggtgaggc tggtaatgtg acggaccgct ggattctcca caatctcaac gaaaccattg
    39181 caaaagttac tgaaaacttt gataagttcg agtttggtgt ggctggtcat atcctttaca
    39241 acttcatctg ggaagaattt gccaactggt atgttgagtt gaccaaggaa gttctataca
    39301 gcgacaatga agacgataag gtcattactc gatctgttct cctctatacg ctggacaaga
    39361 tccttcgtct ccttcaccca atcatgccat tcgtgacaga ggaaatcttt ggacaaatct
    39421 cagaaggttc tatcgtgaca gctgcatacc caactgttaa tctagccttt gaagaccttg
    39481 ctgcccacac tggtgtggaa agtctcaaag acttgatccg tgccgttcgt aatgcgcgtg
    39541 cggaagtaaa tgtagcacca agcaaaccta tcacaatcct tgttaagact agcgatagtg
    39601 acttggaagc cttctttaac agcaatgtca actacatcaa acgctttaca aatccagaac
    39661 atttggaaat cgcatcaacc atccctgcac ctgaactggc tatgtcaagt gtcatcacag
    39721 gagcagaaat ctacctgcca ctggccgatc tcctcaatgt tgaagaagaa ctagctcgtc
    39781 tcgacaaaga actcgctaaa tggcaaaaag aactggacat ggttggtaag aaactctcta
    39841 acgaacgctt cgtagccaac gccaaaccag aagtcgtcca aaaagaacgt gacaaacaag
    39901 ctgactacca agccaagtat gatgcgaccg tagcacgtat tgatgagatg aagaagttgg
    39961 tgaaataaac aattatataa atttaataaa acacagtgta aaaactgtgt ttttatggta
    40021 taatcaatat tataaatatt tattgaaagt tgagactttt ttatggcaca aaataaactt
    40081 gtcagaagaa attttgatat atcgtttaat gaactttatg atatgtataa tgatggcgaa
    40141 ttagttatta agccagaatt ccaaagatta tttagatggt cattaacaca gcaatctctc
    40201 tttattgagt cccttctttt agatatgcct atacctccta tttatgtaga tgagcaagaa
    40261 gatgggaggt atgttctagt agatggacta caaagaattt catcttatct aaatttcaga
    40321 ggcataacgt tagattctcc agaattaact gctattgatc cagatgatga tgactgcgag
    40381 atagactttg agcgagttga accaggtttt caattatcag gttgtgaaat tattgatgat
    40441 ttgaatggta aagaatttga cgagttaagc atagaggaaa aacggcaatt aaaacgtacg
    40501 tttattcgag tagaagtctt aacaaaagaa aatccaaaag aaattaaata tcatatgttt
    40561 aaaagattaa attctggtgg agcattgcta tctaaacaag aattaagaaa cagtaatata
    40621 cgcatgattg acgagaagtt cataaacttt attaatgaac tggctaactc tgaagatttt
    40681 gttgaattga cacattacat gacagaatct gataagcagc aaatgaagag agctgaagtt
    40741 gttttaagat tcttcttgtt taaaaataaa tttattaatg ataatcccga tgtaagaatg
    40801 ggatttttag atgatgaact tacgacctat ttagaagaag tttcctcaca gaagtttcct
    40861 tttgaatatg aaacagaaaa ggaaaacttt ttgagtttag tttcgtatct taaaaatcat
    40921 tttggtagtg ttattttcag tggtatcagc aaaaacaata ctatttctaa aagatttgtc
    40981 cagtataact acgacggttt tatgcaatat ttctcaaaag agagcaatag agattcatca
    41041 attactattg ataagattaa tgagataaaa aatagtgatg agtataagca ataccgaact
    41101 ggggggcttg aaaattctag aaaacgcgtt gaggtaatag cagggaaagt aaatgagtga
    41161 tattagggat tctcttgaca aaattttagc agtttcaatc gatagtatta aagatgaaca
    41221 gaatttttta aatttagtat tatccgactc tcctgagggt aatattctaa aagaactagc
    41281 aatctttaag gataatggag cattatataa attgatattt tcagtctatg ctacctttga
    41341 gtataccatc aaggaatgct gtaatactgc cttactaaca atcgataaaa atagtctaga
    41401 ttcattgaca gatgaactac aaatgctaac ttttcgacaa aagctagatg aattacgcaa
    41461 aaaaataatt gagaagagag aagataacac agttattaaa ccacttacgg acttgcatat
    41521 caaaattaaa caacaaaccg aattcaatag caatgaaaat atgattgata cgaaatcaaa
    41581 tctgaatttc aataatttta cagaaattct tgaaatattt cattttgata aaaagaaata
    41641 taaatcctat tcaattatca ttgattcaat aataacttat cgaaatatga ttgctcatgg
    41701 aaacagaaag gatttaacgg agataaacat tagacaatat attcctggaa attataaaat
    41761 tattactctt cataaagaaa ataatcgact ttattttgaa gatttatgta gtgatatgat
    41821 taatcttctt aaactatttt gtcaggatct tacagattat gtaaacgaac aaaagtattt
    41881 acgtcaagat aagtgaatat tattttaaat aattaaaaaa gaacgacatt ctaaaagtta
    41941 aactaagaat attatcttta tagaataaca tagaaacatg gtgtaatgcc gtgtttt
//
LOCUS       DAVDZK010000017        40801 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVDZK010000017 DAVDZK010000000
VERSION     DAVDZK010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40801
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.018"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..584
                     /locus_tag="VUX16_001043"
     CDS             <1..584
                     /locus_tag="VUX16_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET8124023.1"
                     /translation="QREGDTHHSYKHIAPVYAIAIVDSNYFQDDLAFHSFSMREDTTG
                     EVLTITTNGQENHLVKMAFLELKKYRETSKDEVRKPWLEFFGNKPFTQEPERAISQAD
                     QLLDYKSWSEEDRKMFSQLRMREEQALLAHDYSLEQAEEKGLERGRAEGLERGLERGK
                     LFAFLDMVRQGLLTSEVASQQLGMTVAEFEALL"
     gene            1615..2067
                     /locus_tag="VUX16_001044"
     CDS             1615..2067
                     /locus_tag="VUX16_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET8124024.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            2086..3423
                     /locus_tag="VUX16_001045"
     CDS             2086..3423
                     /locus_tag="VUX16_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET8124025.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            3502..4386
                     /locus_tag="VUX16_001046"
     CDS             3502..4386
                     /locus_tag="VUX16_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET8124026.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            4386..5219
                     /locus_tag="VUX16_001047"
     CDS             4386..5219
                     /locus_tag="VUX16_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET8124027.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            5237..7330
                     /gene="nanB"
                     /locus_tag="VUX16_001048"
     CDS             5237..7330
                     /gene="nanB"
                     /locus_tag="VUX16_001048"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET8124028.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHSNELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            7342..8445
                     /locus_tag="VUX16_001049"
     CDS             7342..8445
                     /locus_tag="VUX16_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET8124029.1"
                     /translation="MVKYGVVGTGYFGAELARYMQKNDGAEITLLYDPDNTEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHRAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            8618..9316
                     /locus_tag="VUX16_001050"
     CDS             8618..9316
                     /locus_tag="VUX16_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET8124030.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPHEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVKAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            9335..10256
                     /locus_tag="VUX16_001051"
                     /pseudo
     CDS             9335..10256
                     /locus_tag="VUX16_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
     gene            10381..11709
                     /locus_tag="VUX16_001052"
     CDS             10381..11709
                     /locus_tag="VUX16_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET8124031.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11961..12827
                     /locus_tag="VUX16_001053"
     CDS             11961..12827
                     /locus_tag="VUX16_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET8124032.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSITKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12843..13682
                     /locus_tag="VUX16_001054"
     CDS             12843..13682
                     /locus_tag="VUX16_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET8124033.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13742..14086
                     /locus_tag="VUX16_001055"
     CDS             13742..14086
                     /locus_tag="VUX16_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124034.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIINGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLGADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            14373..15017
                     /locus_tag="VUX16_001056"
     CDS             14373..15017
                     /locus_tag="VUX16_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET8124035.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEIKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15186..16103
                     /locus_tag="VUX16_001057"
     CDS             15186..16103
                     /locus_tag="VUX16_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET8124036.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16121..17005
                     /locus_tag="VUX16_001058"
     CDS             16121..17005
                     /locus_tag="VUX16_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET8124037.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFQEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17021..17872)
                     /locus_tag="VUX16_001059"
     CDS             complement(17021..17872)
                     /locus_tag="VUX16_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET8124038.1"
                     /translation="MDKPDIATVIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18080..20122
                     /gene="pbp2b"
                     /locus_tag="VUX16_001060"
     CDS             18080..20122
                     /gene="pbp2b"
                     /locus_tag="VUX16_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET8124039.1"
                     /translation="MRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNKDFYEK
                     KLASASQTKVTSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKEIAKKLLT
                     YVSISSPNLTERQLADYYLSDPEIYKKTVEALPSEKRLDSDGNRLSESELYNNAVDSV
                     PTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMPGISIS
                     TSWDRKILETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQYEETL
                     QGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFNSELGN
                     GGAKYSEGVYAVALNPKTGAVLSMSGLKHDLKTGELTPDSLGTVTNVFVPGSVVKAAT
                     ISSGWENGVLSGNQTLTDQPIVFQGSAPIYSWYKLAYGSFPITAVEALEYSSNAYMVQ
                     TALGIMGQTYQPNMFVGTSNLETAMGKLRATFGEYGLGAATGIDLPDESTGFVPKEYS
                     FANYITNSFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGDLIQQL
                     QPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTAESYVA
                     DGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYHPMN"
     gene            20133..20729
                     /gene="recR"
                     /locus_tag="VUX16_001061"
     CDS             20133..20729
                     /gene="recR"
                     /locus_tag="VUX16_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET8124040.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSDDDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            20905..21948
                     /locus_tag="VUX16_001062"
     CDS             20905..21948
                     /locus_tag="VUX16_001062"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET8124041.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSQTPGQEDRLMTNATIDWDKKVSPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFQYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKEEIFLNELNTMPGFTQWSMYPLLWDNMGISYPDLIEHLVAL
                     AKESFDKREAHLL"
     gene            22033..23406
                     /locus_tag="VUX16_001063"
     CDS             22033..23406
                     /locus_tag="VUX16_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET8124042.1"
                     /translation="MKLTIHEVAQAVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTVIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDTVIFYGQDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENEAK"
     gene            23393..24004
                     /locus_tag="VUX16_001064"
     CDS             23393..24004
                     /locus_tag="VUX16_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET8124043.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDVEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            24095..24799
                     /locus_tag="VUX16_001065"
     CDS             24095..24799
                     /locus_tag="VUX16_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET8124044.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25018..26391
                     /gene="ftsA"
                     /locus_tag="VUX16_001066"
     CDS             25018..26391
                     /gene="ftsA"
                     /locus_tag="VUX16_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET8124045.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26408..27667
                     /gene="ftsZ"
                     /locus_tag="VUX16_001067"
     CDS             26408..27667
                     /gene="ftsZ"
                     /locus_tag="VUX16_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET8124046.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQVSAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27672..28343
                     /locus_tag="VUX16_001068"
     CDS             27672..28343
                     /locus_tag="VUX16_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET8124047.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28353..28892
                     /locus_tag="VUX16_001069"
     CDS             28353..28892
                     /locus_tag="VUX16_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET8124048.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            28892..29155
                     /locus_tag="VUX16_001070"
     CDS             28892..29155
                     /locus_tag="VUX16_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET8124049.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29152..29937
                     /locus_tag="VUX16_001071"
     CDS             29152..29937
                     /locus_tag="VUX16_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HET8124050.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPLAEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLKLLQDKGQTKKEKKKITVQLLLSK"
     gene            29946..30735
                     /locus_tag="VUX16_001072"
                     /pseudo
     CDS             29946..30735
                     /locus_tag="VUX16_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
     gene            31083..33875
                     /locus_tag="VUX16_001073"
     CDS             31083..33875
                     /locus_tag="VUX16_001073"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET8124051.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNSPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLISLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTVVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDTKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDAVAYEELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAETFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTMAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAGGFEEK"
     gene            34058..39877
                     /locus_tag="VUX16_001074"
     CDS             34058..39877
                     /locus_tag="VUX16_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HET8124052.1"
                     /translation="MRQTNVRGSLSLRGFRKLRTGAIVATGVILLGLGFSAPTASVSE
                     QDGVWVARTVAEVKADIQKEGDLFKYVIKWGDTLSVISEASNIPVDVLQEMNQASGKN
                     LFLPYNELYFTEAETVSDTVTKHKIVIKESGASGEVRTYEVLLKKDQETKAVTFELTD
                     VTEKVEKMTVNYSPVYQPVSVPVVERAEESVEEPALVAPAVTSPEVKEETEDPVVLKA
                     EEAATTPATKETAPEVVTPAEPNAETPAPKVEAPTESSEPKGTEPEVAKPAGDSVSST
                     SESNEDGNSGDSTHSTLTSDETKPEEVESTSVTDNVPSNAGTTNQPLTPTSNSDDSAP
                     KEVANGTEGKVEAPKVEEAVSEGEEGNAEITNNPSTGATPSSDETTEQSGTPAPKPEE
                     EAPVATETSAASAESTESAPVVAKPAEPKAETPEATITGDEGKESEESGTSATVESTP
                     AGEEGKAEDSVSSTESSSTASEGESTATQPAVEAGTDSTSEAEELATTETATTPKTEE
                     PEAVAPAPEAPSESDSKEEDSAAGDTTVTEEQPAAETVSEGGSPATQPAGEEGKSEKE
                     PKVEGQPSGTESATPEQHTNIEETTEKQSGATSENSGDSLVSDEPAASSGISTSSGTE
                     GAETIDTETIAEKSEIPSPAEEGSAKEEKEVIKKLELRNISSVELYSKEGDKYRHVTS
                     LATLPSNPETYFMKVKSENFKDVMLPVTSITNDNKDNRDVYKIVASVKNLIQHENNKV
                     LENYTYYLSKTQQGETGVYTSFKNLVDAMNRDSYGEFRLGATMDAREVELPDGQESYV
                     KNVFHGRLIGQNSNKYYAIYNLKKPLFNALSNARVQNLSLKDVNISAKDDTATLAKEA
                     NNNTHIDNVHSDGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLV
                     GKLSGPNGLIDKSIASIDLASNATRGDQSIGGIAGSVIDNAVISSSYAEGKLNNVQPF
                     ANVGGVVGDLWDPVGGLEKSGQLSNVLSDVNVTNGNAIAGKHFDHMKATNVYSNKNNK
                     VVNVVQENDEILTKDSVVQRGEVLEDEQIKEKKAAFVTKNTVKTEDFNFSSRYVTDYK
                     NLENADSSKEKVYKNIEKLLPFYNSETIVKYGNLVETSSNLYNKELLSVVPMKDKEVI
                     SDINKNKSSINKLLLYYADNSYETLNVNYQSDFSNVAEYSIGGTNLIYTPNTLLRDYN
                     NILDGVLPVLETVDYKSDAIRKVLDVSNDVSLTELYLEEQFNTTKNNLRDSLTKLLTA
                     DAAISENSNSIIDNYVIEKIKNNKEALLLGLTYLERWYNFKYGETKAKDLVMYHLDFF
                     GKSNSSALDNVIELGKSGFNNLLAKNNVITYNVLLSKNYKTNNLFDALEKYRKVFVPD
                     KTNNEWFKEQTKAYIVEEKSTIKEVNDKQSKAGTPQSIGVYDRLTSPSWKYPSMVLPL
                     LTLPEKSVFIIANISTIGFGAYDRYRSKEHPAGTNLNDYVEAKAREAAVRFRDHYDYW
                     YKILDNNNKEKLYRSVLVYDAFRFGADDKGERETKQANFETDHPAIKHFFGPAGNNVV
                     HNSNGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYA
                     KGLLQAPDHPDDPTITINSILKYEESEDPTRLQVKDPTKRFNNAEDLQKYMYNMFDVI
                     YMLEYLEGNAVVKLDISKKNELLRKIENKFETDPDGSNVYATNVVRYLKPEELTKLTS
                     FNSLIENDVITRRGYENGNDNTFKRNGYYTIKLFSPIYSALSNNEGTPGDLMGRRMAF
                     ELLAAKGFKDGMVPYISNQYAEEAKAKGKVIKSYGKEVGNVTDELVLQKIFNNRYSSW
                     VEFKKAMYNERIAKFKKLMSISFDNPNGNWFRKDRVTIKNIEDLQRMITTAVNEDAED
                     YLVNIYPERSRVLKLKKAIFKAYLDQTNDFRSSIFDEEK"
     gene            40036..40728
                     /locus_tag="VUX16_001075"
     CDS             40036..40728
                     /locus_tag="VUX16_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET8124053.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
BASE COUNT        13056 a         7018 c         8813 g        11914 t
ORIGIN      
        1 gccaacgaga aggtgataca caccatagtt acaaacatat cgcaccagtt tatgctattg
       61 ccatcgtaga tagtaattac ttccaagatg atttggcctt tcacagtttt agtatgcgcg
      121 aagacacgac aggtgaggtc ttaactatca caactaacgg tcaagaaaac catttggtca
      181 agatggcatt cttggaacta aaaaaataca gagaaaccag caaagacgag gttcgtaagc
      241 cgtggttgga gtttttcggg aacaaaccct ttacccaaga acccgagcga gccatcagcc
      301 aagcagacca actgctggac tacaagagct ggtccgagga ggacagaaaa atgtttagtc
      361 aactacgtat gcgagaagaa caggcattat tggctcatga ctattccttg gaacaagctg
      421 aggaaaaagg gttggagaga ggtcgtgcag aaggacttga acgtggtctt gaacgtggaa
      481 aactttttgc ctttctggat atggttcgcc aaggacttct gacttccgag gttgccagtc
      541 agcagttggg catgaccgtt gctgagtttg aggcgttgtt gtaagatcag caataataga
      601 caggaaaacc atctggtcaa gatggcgttc ttggaattaa aaaactctag gtataaaatc
      661 ttaaaaatta caaacacgca tagtatcagg ggattaagaa accttgatac tatgcgtttt
      721 atagtgcatt gaatctacat tagtacacta tagttgattg aaaacagaat agtataccgc
      781 agcttctaaa tccttgttat aaatttgatt tgactttcct aatcgattta ttctcatctt
      841 atttcaatct gctatattta cttcactttc tcctaaaatt gactttcttg ttttcttatc
      901 ttgtccactc gaaacaagta ttgtaagaat ttgattattt ttgaaagtac ttttaatata
      961 cttgatatag ttaaaaaaga tttgaaacta aattccaaat tagaaaaaga cttgaaatac
     1021 taaaaaaaaa aaagtatact ctaattgaaa acggtaacaa aactaattta gagaatgaaa
     1081 tatagagtat ttctctctta aaagtttttg gtgaaacgag atgtagaaag gagatttagc
     1141 caaagagtct attagtgcta gaataataga ttagaattat tttagaaaaa cgaagtgagc
     1201 agcttataaa ttcaagtccc caaatagatt catactagta tcttttgcaa aaaataaagg
     1261 gcgacttcct tcatgaatat caatttcatc tataaggaag gtagctaatt gaactaactt
     1321 atttattctg tttgtcgcta gaaaaatcag acctccttgt gaagattgag gagatactta
     1381 atgaaaatca aagaagaaac tagcaagcta gtagcagatt gcccaaaaca ccgctttgag
     1441 gttgtagata agactgacgt atataatcca aggtgaagcg actgtggttt gaagagattt
     1501 tcaaagagta taggctagag agtagtgttt ttatgtcctt ctagtagaaa atgctagaca
     1561 gaagaatggg gaacttggat aggaaaaata gattgagaaa ggaggttaga agagatgatt
     1621 attacaaaaa ttagccgttt aggaacttat gtgggagtaa atccacattt tgcaacatta
     1681 atagattttc tagaaaaaac aggactagaa aatttaacag aaggttcgat tgctatcgat
     1741 ggtaatcgat tgtttgggaa ttgctttact tatctagcag atggtcaagc aggggctttc
     1801 tttgaaacac accaaaaata tttggatatt catttagttt tggaaaacga agaagccatg
     1861 gctgttacat cgccggaaaa tgtaagcgtt acccaagagt atgatgaaga gaaagatatt
     1921 gaattataca cagggaaagt ggaacagttg gttcatttga gagctggcga atgcctcatc
     1981 acttttccag aagatttaca tcaacccaag gttcgtataa atgatgaacc tgtgaaaaaa
     2041 gttgtcttta aagttgcgat ttcttaatgt agaaagagaa gaacgatgaa aaaaatgaga
     2101 aagtttttat gtctagctgg aattgcgcta gcggctgttg ccttggtagc ttgttcagga
     2161 aaaaaagaag ctacaactag tactgaacca ccaacagaat tatctggtga gattacaatg
     2221 tggcactcct ttactcaagg accccgttta gaaagtattc aaaaatcagc agatgctttc
     2281 atgcaaaagc atccaaaaac gaaaatcaag attgaaacat tttcttggaa tgacttctat
     2341 actaaatgga ctacaggttt agcaaatgga aatgtgccag atatcagtac agctcttcct
     2401 aaccaagtaa tggaaatggt caactcagat gctttggttc cgctaaatga ttctatcaag
     2461 cgtattggac aagataaatt taacgaaact gccttaaatg aagcaaaaat cggagatgat
     2521 tactactctg ttcctcttta ttcacatgca caagtcatgt gggttagaac agatttgtta
     2581 aaagaacata atattgaggt tcctaaaact tgggatcaac tctatgaagc ttctaaaaaa
     2641 ttgaaagaag ctggagttta tggcttgtct gttccgtttg gaacaaatga cttaatggca
     2701 acacgtttct tgaacttcta cgtacgtagt ggcggaggaa gcctcttaac aaaagatctt
     2761 aaagcagact tgacaagcca acttgctcaa gatggtatta aatactgggt taaattgtat
     2821 aaagaaatct cacctcaaga ttctttgaac tttaatgtcc ttcaacaagc taccttgttc
     2881 tatcaaggaa aaacagcatt tgactttaac tctggcttcc atatcggagg aattaatgcc
     2941 aacagtcctc aattgattga ttcgattgat gcttatccta ttccaaaaat caaagagtct
     3001 gataaagacc aaggaattga aacctcaaac attccaatgg ttgtttggaa aaattcaaaa
     3061 catccagaag ttgctaaagc attcttagaa gcactttata atgaagaaga ctacgttaaa
     3121 ttccttgatt caactccagt aggtatgttg ccaactatta aggggattag cgattctgca
     3181 gcctataaag aaaatgaaac tcgtaagaaa tttaaacatg ctgaagaagt aattactgaa
     3241 gctgttaaaa aaggtactgc tattggttat gaaaatggac caagtgtaca agctggtatg
     3301 ttgactaacc aacacattat tgaacaaatg ttccaagata tcattacaaa tggaacagat
     3361 cctatgaaag cagcaaaaga agcagaaaaa caattaaacg atttatttga ggctgttcag
     3421 tagatgtaaa agactagaaa ataggtgggc tagtgagctg aaaagctcta gcccaatctt
     3481 gtaaaagaag ggagaaggag aatggttaaa gaacgtaatt taactcgctg gatatttgtt
     3541 ttgccagcta tgattatcgt aggattactc tttgtttatc cgtttttctc gagtattttt
     3601 tatagcttta ccaataagca tttgattatg cctaattata aatttgttgg tttggctaac
     3661 tataaagctg tgctatcaga tcccaacttc tttaatgcgt tctttaattc aattaagtgg
     3721 accgttttct cattagttgg tcaagtttta gtagggtttg tattggcttt agctcttcac
     3781 agagtacgcc acttcaagaa attatatagg accttattga ttgttccttg ggcatttcct
     3841 accatcgtta ttgccttttc ttggcagtgg attctaaacg gggtttatgg ctacttacct
     3901 aatctaatcg taaaattagg tttaatggaa catacacctg catttttgac agatagtaca
     3961 tgggcattcc tatgtttggt gtttatcaac atttggtttg gagcaccaat gattatggtt
     4021 aatgtgcttt cagctttgca aacagtacca gaagaacaat ttgaggctgc taagatagat
     4081 ggtgcttcaa gttggcaggt gttcaagttt atcgtctttc cacatattaa agtggttgta
     4141 ggacttctag ttgttttgag aactgtatgg atctttaata actttgacat tatctaccta
     4201 attactggtg gtggaccagc caatgctaca acgacgcttc caatttttgc ttacaacctg
     4261 ggttggggaa ctaaattgtt gggtcgtgct tcagcagtta cagtattgct ctttatcttc
     4321 ttggtggcga tttgctttat ctactttgct atcatcagta agtgggaaaa ggagggtaga
     4381 aaataatgaa gaagaaatcc agtatttatt tagatattct ctcacatgta cttttagttg
     4441 gtgcgaccat cgttgcaatt ttcccattgg tatggattat catatcttct gtcaaaggga
     4501 aaggggaatt aactcagtat ccaacacgat tttggcctga acagtttaca ttagattatt
     4561 tcactcatgt tatcaacgat ttgcacttca ttgataatat tcgaaacagt ttaatcattg
     4621 ccttggctac aaccctcatt gcgattatta tttctgctat ggcagcctat ggtattgttc
     4681 gattctttcc taaattggga gcaatcatgt cgagactact cgtcattacc tacattttcc
     4741 caccaatttt gttagcaatt ccctattcaa ttgccattgc taaagttggg ttaacaaata
     4801 gtttatttgg cttgatgatg gtttatctat cttttagtgt tccatatgca gtttggctct
     4861 tagttggatt tttccaaaca gttccaattg gaattgaaga agcggctaga attgatggtg
     4921 caaataaatt tgttacgttt tataaagttg tgctaccgat tgtagcacca ggtattgtag
     4981 caacagctat ttatacattt atcaatgctt ggaatgaatt cctgtatgcc ttgattttga
     5041 ttaacaatac aggaaagatg acagtagcag tagcccttcg ttcacttaat ggttcagaaa
     5101 tactagactg gggagatatg atggcagcgt ctgttattgt agttcttcca tcaattattt
     5161 tcttctctat catccaaaat aagattgcaa gtggattatc agaaggatct gtgaagtaga
     5221 cgaaagaagg aaaaaaatga ataaaagagg tctttattca aaactaggaa tttctgttgt
     5281 aggcattagt cttttaatgg gagtccccac tttgattcat tcgaatgaat taaactatgg
     5341 tcaactgtcc atatctccta tttttcaagg aggttcatat caactgaaca ataagagtat
     5401 agatatcagc cctttgttat tagataaatt gtctggagag agtcagacag tagtaatgaa
     5461 atttaaagca gatgaaccaa actctcttca agctttgttt ggcctatcta atagtaaagc
     5521 aggctttaaa aataattact tttcaatttt catgagagat tctggtgaga taggtgtaga
     5581 aataagagac gcccaaaagg gaataaatta tttattttcc agaccagctt cattatgggg
     5641 aaaacataaa ggacaggcag ttgaaaatac actagtattt gtatctgatt ctaaagataa
     5701 aacatacaca atgtatgtta atggaataga agtgttctct gaaacagttg atacattttt
     5761 gccaatttca aatataaatg gtatagataa ggcaacacta ggagctgtta atcgtgaagg
     5821 taaggaacat taccttgcaa aaggaagtat tgatgaaatc agtctattta acaaagcaat
     5881 tagtgatcag gaagtttcaa atattccctt gtcaaatcca tttcagttaa ttttccaatc
     5941 aggagattct actcaagcta actattttag aataccgaca ctatatacat taagtagtgg
     6001 aagagttcta tcaagtattg atgcacgtta tggtgggact catgattcta aaagtaagat
     6061 taatattgcc acttcttata gtgatgataa cgggaaaacg tggagtgagc caatttttgc
     6121 tatgaagttt aatgactatg aggagcagtt agtttactgg ccacgagata ataaattaaa
     6181 gaatagtcaa attagtggaa gtgcttcatt catagattca tccattgttg aagataaaaa
     6241 atctgggaaa acgatattac tagctgatgt tatgcctgcg ggtattggaa ataataatgc
     6301 aaataaagcc gactcaggtt ttaaagaaat aaatggtcat tattatttaa aactaaagaa
     6361 gaatggagat aacgatttcc gttatacagt tagagaaaat ggtgtcgttt atgatgaaac
     6421 aactaataaa cctacaaatt atactataaa tgataagtat gaagttttgg agggaggaaa
     6481 gtctttaaca gtcgaacaat attcggttga ttttgatagt ggctctttaa gagaaaggca
     6541 taatggaaaa caggttccta tgaatgtttt ctacaaagat tcgttattta aagtgactcc
     6601 tactaattat atagcaatga caactagtca gaatagagga gagagttggg aacaatttaa
     6661 gttgttgcct ccgttcttag gagaaaaaca taatggaact tacttatgtc ccggacaagg
     6721 tttagcatta aaatcaagta acagattgat ttttgcaaca tatactagtg gagaactaac
     6781 ctatctcatt tctgatgata gtggtcaaac atggaagaaa tcctcagctt caattccgtt
     6841 taaaaatgca acagcagaag cacaaatggt tgaactgaga gatggtgtga ttagaacatt
     6901 ctttagaacc actacaggta agatagctta tatgactagt agagattctg gagaaacatg
     6961 gtcggaagtt tcgtatattg atggaattca acaaacttca tatggcacac aagtatctgc
     7021 aattaaatat tctcaattaa ttgatggaaa agaagcagtc attttgagta caccaaattc
     7081 tagaagtggc cgtaagggag gtcaattagt tgtcggttta gtcaataaag aagatgatag
     7141 tattgattgg aaatatcact atgatattga tttgccttcg tatggttatg cctattctgc
     7201 gattacagaa ttgccaaatc atcatatagg tgtactgttt gaaaaatatg attcgtggtc
     7261 gagaaatgaa ttgcatttaa gcaatgtagt tcagtatata gatttggaaa ttaatgattt
     7321 aacaaaataa aggagaaaaa catggttaaa tacggtgttg ttggaacagg gtattttgga
     7381 gctgaattgg ctcgctacat gcaaaagaat gatggagcag agattactct tctctatgat
     7441 ccggataata cagaggcgat tgcagaagaa ttgggagcaa aagtagcaag ttccttagat
     7501 gagttggttt ctagcgatga agtagattgt gtcatcgtcg caactccaaa taatcttcat
     7561 aaggaaccgg ttattaaggc tgcacagcat ggtaaaaatg ttttctgtga aaaaccaatt
     7621 gcgctttctt atcaagattg tcgcgagatg gtagatgcat gtaaagaaaa caatgtaacc
     7681 tttatggcag gacatattat gaatttcttt aatggtgttc atcgtgcaaa agaactcatt
     7741 aatcaaggag ttatcggaga cgttctatat tgtcatacag ctcgtaatgg ttgggaagaa
     7801 caacaaccgt cagtatcatg gaaaaaaatt cgtgaaaaat caggtggtca cttgtatcac
     7861 cacatccatg aattggattg cgttcaattc cttatggggg gcatgcctga aactgtaacc
     7921 atgacaggtg gaaatgtggc ccatgaaggt gaacatttcg gtgatgaaga tgatatgatt
     7981 tttgtcaata tggaattttc taataagcgt tttgccttgt tagaatgggg ttcagcttat
     8041 cgttggggtg aacattatgt cttaatccaa ggaagcaaag gtgccatccg cttagactta
     8101 ttcaactgta aaggaactct taagctagat gggcaagaaa gctatttctt gattcacgaa
     8161 tcgcaagaag aagatgatga tcggactcgt atctatcata gtacagagat ggatggagca
     8221 attgcttatg gtaaaccagg taaacgtact ccattatggc tatcatctgt cattgataaa
     8281 gaaatgcgct atctgcatga gattatggaa ggagctccag tatcagaaga atttgcaaaa
     8341 cttttgacag gtgaagctgc cctagaagca attgctactg cagatgcttg tacccagtct
     8401 atgtttgaag atcgcaaagt aaaattgtca gaaattgtaa aataaatttt ggtattctcc
     8461 tattataggt cgacttgctc ctctgaaagt acttttagag gagctgtttg acttggctag
     8521 tttttgaaac tgaaatctat tatactacaa actattgaaa gcgttttaat tttaaggtat
     8581 aataatctca tagaaataaa gaaaaggagg aaagaggatg ccacagatta gcaaagaagc
     8641 cttgattgag caaatcaaag atggaatcat cgtttcttgt caggctcttc ctcatgaacc
     8701 gctttataca gaagcgggag gggtgattcc cttgctggtc aaagcggctg agcaaggtgg
     8761 agcagtcggt atccgagcaa acagtgttcg cgatatcaag gaaattaagg aagtcactaa
     8821 acttccaatc attgggatta tcaaacgtga ttatccacct catgaaccct tcatcacggc
     8881 tactatgaaa gaagttgatg aattggcaga actggacatc gaggtgattg ctctggattg
     8941 taccaagcgt gaacgctacg atggtttgga aattcaagag ttcattcgtc aggttaagga
     9001 gaaatatcct aatcagcttt tgatggctga tactagtatc ttcgaagaag ggctagcagc
     9061 tgtaaaagca ggaattgact ttgtcggaac aaccttatca ggctacacat cctacagtcc
     9121 aaaagtagac ggtccagatt ttgaattgat taagaaactc tgtgatgccg gtgtagatgt
     9181 cattgcagaa ggaaaaattc atacaccaga acaagccaaa caaatccttg aatatggagt
     9241 gcgaggcatc gttgttggtg gcgctattac tagaccaaaa gagattacag aacgcttcgt
     9301 tgctagtctt aaataagatg tgagggggag ttttatgttt aaagttttac aaaaagttgg
     9361 aaaagctttt atgttaccta tagctatact ttctgcagca ggtctacttt tggggattgg
     9421 tggtgcactt tcaaacccaa ccacgatagc aacttatcca atactagaca atagtatttt
     9481 tcaatcaata ttccaagtaa tgagctctgc aggagaggtt gtattcagta atttgtcact
     9541 acttctctgt gtgggattat gtattggctt agcgaaacga gataaaggaa ccgctgcgtt
     9601 agcaggagta actggttact tagttatgac tgtaacgatc aaagctttgg taaaactttt
     9661 tatggcagaa ggatctgcaa ttgatactgg agttattgga gcattagttg tcggaatagt
     9721 tgccgtatat ttgcacaatc gatataacaa tattcaatta ccttccgctt taggattctt
     9781 tggaggttca cgcttcgttc ctattcactt tatttggaat tttgcagggg aacgctaaga
     9841 cgaattgggt tcttcagatt ccatttggac ttatttggag tgttttgtat tatattattt
     9901 ttagatggtt cattactcaa ttcaacgttc taacgccagg acgaggagaa gaagtagatt
     9961 ctaaagaaat ttctgaatcc gcagattcaa cttcaaatac tgcagattat ttaaaacagg
    10021 atagcctaca aattatcaga gccttgggtg gatcaaataa tatagaagat gtagatgctt
    10081 gtgtgacacg tttacgtgta gctgtaaaag aagttaatca agttgataaa gcacttttaa
    10141 aacaaattgg tgcagttgat gtcttagaag tgaagggtgg cattcaagca atctatggag
    10201 caaaagcaat cttatataaa aatagtatta atgaaatttt aggtgtagat gattaagtac
    10261 ttactgactt aataaaaaac agaggagagt gatggatgag taggatgaaa tgaaatcgca
    10321 tacaagaaat aaagaactca ttatccaagt tggatacgct tattacatag gagaatacaa
    10381 atgaaattta gaaaattagc ttgtacagta cttgcgggtg ctgcggttct tggtcttgct
    10441 gcttgtggca attctggcgg aagtaaagat gctgccaaat caggtggtga cggtgccaaa
    10501 acagaaatca cttggtgggc attcccagta tttacccaag aaaaaactgg tgacggtgtt
    10561 ggaacttatg aaaaatcaat catcgaagcg tttgaaaaag caaacccaga tataaaagtg
    10621 aaattggaaa ccatcgactt caagtcaggt cctgaaaaaa tcacaacagc catcgaagca
    10681 ggaacagctc cagacgtact atttgatgca ccaggacgta tcatccaata cggtaaaaac
    10741 ggtaaattgg ctgagttgaa tgacctcttc acagatgaat ttgttaaaga tgtcaacaat
    10801 gaaaacatcg tacaagcaag taaagctgga gacaaggctt atatgtatcc gattagttct
    10861 gccccattct acatggcaat gaacaagaaa atgttagaag atgctggagt agcaaacctt
    10921 gtaaaagaag gttggacaac tgatgatttt gaaaaagtat tgaaagcact taaagacaag
    10981 ggttacacac caggttcatt gttcagttct ggtcaagggg gagaccaagg aacacgtgcc
    11041 tttatctcta acctttatag cggttctgta acagatgaaa aagttagcaa atatacaact
    11101 gatgatccta aattcgtcaa aggtcttgaa aaagcaacta gctggattaa agacaatttg
    11161 atcaataatg gttcacaatt tgacggtggg gcagatatcc aaaactttgc caacggtcaa
    11221 acatcttaca caatcctttg ggcaccagct caaaatggta tccaagctaa acttttagaa
    11281 gcaagtaagg tagaagtggt agaagtacca ttcccatcag acgaaggtaa gccagctctt
    11341 gaatatcttg taaacgggtt tgcagtattc aacaataaag acgacaagaa agtcgctgca
    11401 tctaagaaat tcatccagtt tatcgcagat gacaaagagt ggggacctaa agacgtagtt
    11461 cgtacaggtg ctttcccagt ccgtacttca tttggaaaac tttatgaaga caaacgcatg
    11521 gaaacaatca gcggctggac tcaatactac tcaccatact acaacactat tgatggattt
    11581 gctgaaatga gaacactttg gttcccaatg ttgcaatctg tatcaaatgg tgacgaaaaa
    11641 ccagcagatg ctttgaaagc cttcactgaa aaagcgaacg aaacaatcaa aaaagctatg
    11701 aaacaatagt ccttagttat tctataaaaa gtagtttttt aaagaaccta agagtgtata
    11761 cccccttttc cctctacaca gatagtgtaa gaaaaggggg cttttgttta aaatgtaaga
    11821 aactgtcacg aaattaaaat gaagttctta cataagcgaa tcataaaaaa tttcattttg
    11881 attttaaaac agttcaagaa agtcaaaaaa ttattctatt tgaaagagag gtgccgactg
    11941 tgaaagtcaa taaaatccgt atgcgggaaa cagtgatttc ctacgctttc ctagcaccag
    12001 tattattctt ctttgtcatc tttgtgttgg ctccgatggt gatgggcttc attacaagtt
    12061 tctttaacta ctcaataact aaatttgagt ttgtaggctt ggataactat atccgtatgt
    12121 ttaaagatcc tgtctttaca aaatctctga ttaacacagt tattttggtt attggatctg
    12181 taccagttgt tgttctattc tcactctttg tagcatctca gacctatcat caaaatgtca
    12241 ttgccagatc cttctaccgt ttcgtcttct tccttcctgt tgtaacgggt agtgttgccg
    12301 tgacagttgt ttggaaatgg atttatgacc cactatcagg gattctaaac tttgtcctta
    12361 agtcaagcca catcatcagc caaaacattt cttggttggg agataaaaac tgggcattga
    12421 tggcgattat gattattctc ttgaccactt cagttggtca gcccatcatc ctttatatcg
    12481 ctgccatggg gaatattgac aattcactgg ttgaagcggc gcgtgttgat ggtgcaactg
    12541 agtttcaagt tttttggaag attaaatggc caagccttct tccaacaact ctttatattg
    12601 caatcatcac aacaattaac tcattccagt gtttcgcctt gattcagctt ttgacatctg
    12661 gtggtccaaa ctactcaaca agtaccttga tgtactacct ttacgaaaaa gccttccaat
    12721 tgacagaata cggctatgcc aacacaattg gtgtcttctt ggcagtcatg attgctatcg
    12781 taagctttgt tcaatttaaa gtacttggaa acgacgtaga atactaaaga aaggagacag
    12841 ctatgcaatc tacagaaaaa aaaccattaa cagcctttac tgttatttca acaatcattt
    12901 tgctcttgtt gactgtgctg ttcatctttc cattctactg gattttgaca ggggcattca
    12961 aatcacaacc tgatacaatt gttattcctc ctcagtggtt ccctaaaatg ccaaccatgg
    13021 aaaacttcca acaactcatg gtgcagaacc ctgccttgca atggatgtgg aactcagtat
    13081 ttatctcatt ggtaaccatg ttcttagttt gtgcaacctc atctctagca ggttatgtat
    13141 tggctaaaaa acgtttctat ggtcaacgca ttctatttgc tatctttatc gctgctatgg
    13201 cgcttccaaa acaagttgtc cttgtaccat tggtacgtat cgtcaacttc atgggaatcc
    13261 acgatactct ctgggcagtt atcttgcctt tgattggatg gccattcggt gtcttcctca
    13321 tgaaacaatt tagtgaaaat attcctacag agttgcttga atcagctaag attgacggtt
    13381 gtggtgagat tcgtactttt tggagcgtag ccttcccaat tgtaaaacca gggtttgcgg
    13441 ctcttgcaat cttcaccttc atcaatactt ggaatgacta cttcatgcag ttggtaatgt
    13501 tgacttcacg taacaatttg accatctcac ttggggttgc gaccatgcag gccgaaatgg
    13561 caaccaacta tggtttgatt atggcaggag ctgcccttgc tgctgttcca atcgtcacag
    13621 tcttcctagt cttccaaaaa tccttcacac agggtattac tatgggagcg gtcaaaggat
    13681 aatactctac catgaaattg atctttgtga ggtagagaaa tgagaataaa atatttaaaa
    13741 attggtatct tctaagtatg ctgcaagagc tagtttctta gatggacagg ggattacagt
    13801 tgatgagatg gcttggataa ttaatggcat tgtgaatgga ttgattggta gatacataaa
    13861 attaggtact tatgcagcta agtatggtat tagtatggcg cgctcgatct taagtagggc
    13921 agctgcaact gcggcagcaa gagtaggatt attgactaag atttttggat ggattttacg
    13981 aatagctgtg ctcggagctg atgtatatgg taattttgcc aacaatattg ctgtagcttg
    14041 ggatgcacat gataaaatcc ctaacaatgg tcgtataaac ttttaaaatg cgagaatgaa
    14101 agcactttgt atttttttat tgaatatgtt agcttggaca gtgcttgcaa tgacagtccg
    14161 tggagggcta gatggattta atgagcatac ttggagtact attttaattg cttcgctgtc
    14221 cgggatatat atagattata tgtccataga taaaagtaga aaaaagtcca aaagaaaaaa
    14281 gaaaaaatag atttgttcat ggtagggact tatgaaagct ttactgacaa aaaagaaaac
    14341 agtttacaaa gaaaaatgat ggaggagcaa acatggcaca aaaaggagta agccttatca
    14401 aggcagcatt tgatacagac aactttctca tgcgttttag tgagaaagtc ttggacatcg
    14461 tgacagccaa tcttcttttt gtcgtctctt gtttgcccat cgtgacgatt ggagtggcta
    14521 aaatcagcct ctacgagacc atgtttgaga ttaagaagag cagacgggtg cctgttttta
    14581 aaatctatct aagatctttc aagcaaaatc tgaaactagg tcttcagctg ggtttaatgg
    14641 agttaggaat tgtgtttctt accctttcag atctctatct tttctggggt caaacagctc
    14701 tgcccttcca attgctgaaa gccatttgtt taggtattct gatttttctt actatcgtga
    14761 tgctggctag ttaccctatc gcggcacgtt atgacctatc ttggaaagaa attcttcaaa
    14821 aagggcttat cttggcaagt tttaactttc cttggttctt cctcatgtta gccattcttg
    14881 tcctcattgt gatggttctc tatctgtccg ccttcagtct acttttaggt ggctcagtct
    14941 tcctgctttt tgggtttgga ctattggtct ttatccagac tggattgatg gagaaaattt
    15001 tcgcaaaata ccaataggag ccttatttct gaaactactt tcaaaggctc caaacgctat
    15061 tctataagcg agaaactaaa atctaagtgt ctataagata ttgaaagcct tttcggtaaa
    15121 gtgtatacta aagaagtaaa gaaaaatctg ctttagcaga aaataaaaat aataggagaa
    15181 aatctatgtc agatttgaaa aaatacgaag gtgtcattcc agccttctac gcatgttatg
    15241 atgagcaagg agaagtaagt ccagagcgta cgcgtgcctt ggttcaatac ttcattgata
    15301 aaggtgttca aggtctttat gtcaatggtt cttctggtga atgtatctac caaagcgttg
    15361 aagatcgcaa gttgattttg gaagaagtca tggcggtagc caaaggtaaa ttgaccatta
    15421 ttgcccatgt tgcttgcaat aatactaaag atagtatgga acttgctcgc catgctgaaa
    15481 gcttgggagt agatgctatt gcaacgattc caccaattta cttccgcttg ccagaatact
    15541 cagttgctaa atactggaac gatattagtt ctgcagctcc aaatacagac tacgtgattt
    15601 ataacattcc tcaattggca ggtgttgctt tgactccaag cctttacact gaaatgttga
    15661 aaaatcctcg tgttatcggt gtgaagaact cttctatgcc agttcaagat atccaaacct
    15721 ttgtgagcct tggtggggaa gaccatatcg tctttaacgg tccagatgaa cagttcctag
    15781 gtggtcgcct catgggtgcc aaagctggta tcggtggtac ttatggtgct atgccagaac
    15841 tcttcttgaa actcaaccaa ttgattgcgg ataaagattt agaaacagcg cgtgagttac
    15901 agtatgctat caacgctatc attggtaaat tgactgctac acatggaaat atgtacggtg
    15961 tcatcaaaga agttttgaag atcaatgaag gcttgaatat tggttctgtt cgttcaccat
    16021 tgacaccagt gactgaagaa gatcgtccag ttgtagaagc ggctgctgcc ttgattcgtg
    16081 aaaccaagga gcgcttcctc taatctaaaa ggaggtattt atgacatact acgttgcaat
    16141 tgatatcggt ggaaccaaca tcaagtatgg tttggttgat caagaggggc aacttcttga
    16201 atcgcatgaa atgccaactg aggcgcataa gggtggacct catatcttac aaaagaccaa
    16261 agatatcgta gctagttatt tagaaaaagg cccagtagca ggtgttgcca tatcttctgc
    16321 tgggatggtg gatccggata agggtgagat tttctatgct gggccgcaaa tccctaacta
    16381 cgcaggcacc cagttcaaaa aggaaatcga agaaagcttt actattcctt gtgagattga
    16441 aaatgatgtc aactgtgcag gtcttgctga ggcagtatct ggttcaggca agggagcaag
    16501 tgtgacactt tgcttgacca ttggaacagg tatcggtggt tgcttgatta tggataggaa
    16561 agtcttccat ggttttagca attcagcctg tgaagtcggg tatatgcata tgcaggatgg
    16621 agcttttcaa gacttggctt ctacaacagc tttagtgaaa tatgtagctg aagcccatgg
    16681 agaagatgtt gatcagtgga atggccgacg tatctttcag gaagctactg aaggaaacaa
    16741 aatctgcatg gaaggcattg accgtatggt tgactatcta ggaaaaggtc tggcaaatat
    16801 ttgctacgtt gccaatccag aagtggtcat tcttggtgga ggtatcatgg ggcaagaggc
    16861 tatcctcaaa cctaagatcc gcacagcctt gaaagaggct ttggtaccaa gtttagcaga
    16921 aaaaacacga ttagaatttg cccatcacca aaatacagca gggatgttgg gtgcatatta
    16981 tcattttaag acaaaacaat cctagtttgg ctcagccaaa ctaggatttt cttacacgtt
    17041 tttgtctacg atagccgttg agttttttat tttcccagta gctattaaag attttttcct
    17101 tgctttcgcg attgatttcc aaaaagtagg cataaatcaa atcgataaag aagagcatag
    17161 gaagttgagc ggatattcgt tggatatagg agggttggct gtgggtggct acaagaacag
    17221 tctctgtata ggtctggcta tctttattgg gaacacttgt aaagagtaca gtctttgccc
    17281 ccatctcctt ggcatctaat agactatcta aaatagaagg agttgagcct gaaagtgaga
    17341 agcccagtac tagacaattt tcatccatga tgctggttgt ccaggcaaag ccgtcttggt
    17401 ctgtcaaagc ttcgcagacc acacctagtc gcataaaacg taatttcatt tcacgggcga
    17461 cgaggccaga actccctgtt ccaaagaagt agatacgctc agcatcttcg attagctggg
    17521 caattcgctc tagttggatt tcgtcaatca agtcttgtgt ttgttccctc atattgctat
    17581 aacttctgag gactcgtttg gtcagtggac tgtgcttgga gacttggttg gcttgatttt
    17641 ctgcctgatg ttggtattgg aaaataaatt ctcggtagcc ggtaaagcca cactttttag
    17701 caaagcgggt caaagcagct tgagaaatat gtaatttttg ggtgacttgt tgagaagata
    17761 aatcatctgt aatcgtttca gcttgcaaaa aatagcgagc gatttcttgc tctaggtctg
    17821 tcatttcttc aaaatgggaa tcaatgacag ttgcgatatc tggtttgtcc atgggaaagg
    17881 ctcctttaaa tgagtcgtat tggaaaaagg ctagattatt gaactcttac atttattata
    17941 tcatataata tagggatgaa taaataaaaa cgtatcttac cgtaaaaagg aaaaaagctt
    18001 ctttcttttc cataattttc tgttcaaatt gtggtacaat taagagtaag attttaagtt
    18061 agaaacgaga ctgatttgta tgagaaaatt taacagccat tcgattccga ttcggcttaa
    18121 tttattgttt tcaatcgtca ttttactctt tatgaccatt attggtcgtt tgttgtatat
    18181 gcaggttttg aacaaggatt tttacgaaaa aaagctagcc tcagctagtc agaccaaggt
    18241 cacaagcagt tctgcccgtg gggaaattta tgatgctagt ggaaaacctt tggtagaaaa
    18301 tacgttaaag caggttgttt cctttacgcg tagcaataaa atgacggcta cagacttaaa
    18361 agaaatagct aaaaagttac tgacttatgt gagcatcagc tctcctaatt tgacagaacg
    18421 ccagctggct gattactatt tgtctgatcc tgaaatctat aaaaaaacag tggaggctct
    18481 cccaagtgag aaacgcttgg attcagatgg caatcgccta tccgaatcag aactgtataa
    18541 caatgcggtc gatagtgtcc caacaagtca actaaactat acagaggatg aaaagaaaga
    18601 aatctatctt tttagtcagt taaatgctgt tggaaacttt gcgacaggaa ccattgcgac
    18661 agatcctcta aatgattctc aggtggctgt cattgcctct atttcaaagg agatgcctgg
    18721 cattagtatt tctacttctt gggatcgaaa gattttggaa acttcccttt cttctatagt
    18781 agggagtgta tccagtgaaa aagctggtct cccagcggaa gaagcagaag cctatcttaa
    18841 aaaaggctat tctctaaatg accgtgttgg aacctcgtat ttggaaaagc aatatgaaga
    18901 gaccttacaa ggaaaacgct cggtaaaaga aatccatctg gataaatatg gcaatatgga
    18961 aagcgtggat acaattgagg aaggtagtaa gggaaacaat atcaaactga ccattgattt
    19021 ggccttccaa gatagcgtgg atgctttgct gaaaagttat ttcaattccg agctaggaaa
    19081 tggtggagcc aagtattctg agggtgtgta tgcagtcgcc cttaacccca aaacaggtgc
    19141 tgttttgtct atgtcaggac tcaaacatga cctgaaaacg ggagagttga ctcctgattc
    19201 cttgggaacg gtaaccaatg tctttgtccc aggttcggtt gttaaggccg ctaccatcag
    19261 ctcaggttgg gaaaatggtg ttttatcagg aaaccaaacc ttaacagatc agcctattgt
    19321 tttccaaggt tcagctccaa tttattcttg gtataaattg gcatatggat cttttcctat
    19381 tacagctgtg gaagccttgg agtattcatc caatgcttac atggttcaaa ccgctcttgg
    19441 aatcatgggc cagacctatc aaccaaatat gtttgttgga accagcaatt tggaaacagc
    19501 tatgggaaaa cttcgtgcga cctttggcga atatggcttg ggggctgcga ccggaattga
    19561 cctaccagat gaatctactg gatttgttcc caaagagtat agctttgcta attacatcac
    19621 caattccttt gggcagtttg ataactatac gcccatgcag ttggctcagt atgtagcaac
    19681 tattgcaaat gatggtgttc gtgtggctcc tcgtattgtt gaaggcattt atggtaataa
    19741 tgataaggga ggactgggtg acttgattca gcaactgcaa ccgacagaga tgaataaggt
    19801 caatatatcc gactccgata tgagtatctt gcaccaaggt ttttatcagg ttgctcatgg
    19861 gactagcggc ttgacaactg gacgtgcctt ttcaaatggt gccttggtat ccattagcgg
    19921 aaaaacgggt acagccgaaa gctatgtggc agatggtcag caagcaacca ataccaatgc
    19981 ggtggcctat gccccatctg ataatcccca aatcgctgtt gcagtggtct ttcctcataa
    20041 taccaatcta acaaatggtg taggaccttc cattgcgcgt gacattatca atctgtatca
    20101 aaaataccat ccaatgaatt agaaaggaaa ttatgcttta tccaacaccc attgccaagc
    20161 tgattgacag ttattccaag ttaccaggta tcgggattaa gacggctacg cgtctggcct
    20221 tttatacgat tgggatgtct gatgatgatg tcaatgaatt tgcaaaaaat ctcctttctg
    20281 ctaagagaga attgacctac tgttccattt gtggacgttt gacagacgac gatccttgtt
    20341 ctatctgtac cgatccgact cgtgaccaga caacgatttt ggtgctagag gatagtcgtg
    20401 atgtggcggc catggaaaat atccaagaat accatggcct ctatcatgtt ctgcatggcc
    20461 tcatttctcc tatgaatggc attagtccag acgatatcaa tctcaagagt ctcatgactc
    20521 gtcttatgga tagtgaggtt tcagaagtaa tcgtagcaac caatgccaca gcagatgggg
    20581 aagcgacttc catgtatctt tcacgtttgc tcaagccagc tggcatcaag gttacgcgcc
    20641 tggcgcgagg cctcgctgtg ggagcagata tcgagtatgc ggacgaagtg accctcttac
    20701 gggctattga aaatcgaaca gagttgtaag tgtagacaaa tttacgaact ctattcattt
    20761 ataaaaaatc aaagaggctg aaaatcgttc ctatcggcct ctttttgtat agtgtgatgg
    20821 gtaggttcag gttcaagttt taaaaaaaca agcaaatgtg atatactaaa gagcgagtat
    20881 tctagtagaa ttaggacaag taatatgaaa caaacgatta ttcttttata tggtggacgg
    20941 agtgcggaac gcgaagtctc tgtcctttca gcggaaagtg tcatgcgtgc ggttaactac
    21001 gaccgtttca cagttaagac tttctttatc agtcagtcag gtgattttat caaaacgcag
    21061 gaatttagtc agactccagg tcaagaggac cgtctcatga ccaatgcgac cattgattgg
    21121 gataagaaag tttcaccaag tgccatctac gaagaaggtg cggtagtctt tccggttctt
    21181 cacggtccga tgggggagga tggctctgtt caaggattct tggaagtttt gaaaatgcct
    21241 tatgtcggct gtaatatctt gtcatcaagt cttgccatgg ataaaatcac gaccaagcgt
    21301 gtgttagaat ctgcaggcat tgcccaagtt ccttatgtgg ctatcgttga aggggatgat
    21361 gtgactgcta aaatcgctga agtggaagaa aaattggctt atccagtctt cactaagccg
    21421 tcaaacatgg gttctagtgt cggtatttct aaatctgaaa accaagagga actccgtcaa
    21481 gctttgaaac ttgccttcca atatgacagc cgtgtcttgg ttgagcaagg ggtgaatgcc
    21541 cgtgaaatcg aggttggact cttgggaaat tacgatgtca agagcacgct tccaggagaa
    21601 gtagtcaagg atgttgcctt ttatgactac gatgccaagt atattgataa caagattact
    21661 atggatattc ctgccaaaat cagtgatgat gtggtagctg tcatgcgtca aaatgcagaa
    21721 acagccttcc gtgccattgg tggcctcggt ctctctcgtt gcgatttctt ctatacagat
    21781 aaggaagaga ttttcctaaa cgagctgaat accatgccag gcttcaccca gtggtctatg
    21841 tatccactac tttgggataa tatgggaatc agctacccag acctaatcga gcatttggtt
    21901 gcccttgcta aggaaagttt tgataagcgc gaagcgcatt tgctataaaa atgaaagaga
    21961 gggtagaagc cagaactatc actgcaaggt gatcagagtt ctcggacttc aacccttttt
    22021 aaaggagtag aaatgaaatt aacaatccat gaggttgccc aagctgttgg agctaaaaat
    22081 gatatcagta tctttgagga cacccagtta gaaaaagctg agtttgatag tcgtttgatt
    22141 ggaactggag atttatttgt gccacttaaa ggtgcgcgtg atggccatga ctttattgaa
    22201 acagcctttg aaaatggtgc agcagtaacc ttgtctgaga aagaggtctc aaatcatcct
    22261 tacattctag tagatgatgt tttgacagcc tttcaatcct tagcatccta ctatcttgaa
    22321 aaaacgactg ttgatgtctt tgctgttaca ggttcaaatg gcaagacaac gactaaggat
    22381 atgttggcgc atttactgtc aacaagatac aagacctaca aaacacaagg caattacaat
    22441 aatgagattg gccttcctta cacagttctt catatgcctg aaggaacaga aaagttggtt
    22501 ttggagatgg gacaggatca cttgggcgat attcatctct tgtctgaatt ggctcgtcca
    22561 aaaacagtca tcgtgacctt ggttggagaa gcccatttgg cctttttcaa agaccgttca
    22621 gagattgcta agggaaaaat gcaaattgca gacggaatgg cttcaggttc cttgctttta
    22681 gcgccggctg accctatcgt agaggactat ttgccaactg ataaaaaggt ggttcgtttt
    22741 gggcaagggg cagagctgga aattactgac ttggttgagc gcaaagatag tctgaccttc
    22801 aaggccaatt tcttagagca agcccttgat ttgccagtaa ctggcaagta caatgcgaca
    22861 aatgctatga ttgcatccta tgttgccttg caagaaggag tttcagagga gcaaattcgt
    22921 ttggccttcc aagatcttga attgacgcgt aaccgtaccg agtggaagaa agcagccaat
    22981 ggagcagata tcctgtcaga tgtttacaat gccaatccaa ctgctatgaa actgatttta
    23041 gagaccttct ctgccattcc agccaatgaa ggtggcaaga aaattgcagt gttggcggat
    23101 atgaaggagc ttggtgacca gtctgttcaa cttcataatc agatgatttt gagcctttct
    23161 ccagatgtgc ttgataccgt gattttctat ggacaagata ttgctcagtt ggctcaattg
    23221 gccagtcaaa tgttcccaat cggccacgtt tactacttca agaaaacaga agaccaggat
    23281 caatttgaag acctagtcaa gcaggttaag gaaagccttg gagcctatga ccaaatcttg
    23341 ctaaaaggtt ctaactctat gaatctagcc aaattggtag aaagtttaga aaatgaagcc
    23401 aagtgatttt gttaagtatc tgcaaagaat gattgccctt acagatactg gcttaacctt
    23461 tacaaaagat ccttttgacc gtgagcgcta cgaggacttg cgaagtctgt tatctgaaat
    23521 gttgaatcag ggatcagacc tggatgtaga agaagtagca gaagtcttga aaccaacttc
    23581 agcttatgcg actcccttaa tggacgtccg tgcttggatt gttgaggatg agaagatttg
    23641 tctggttagg ggacaaggag aggatagttg ggctttgcca ggtggctttg gtgaagtcgg
    23701 ctattctcca actgaaaata ttctcaagga aattgaagaa gaaaccggtt ttaaagccaa
    23761 agttgaaaga ctgctagctg tttttgatac caatcgtttc caactacaga gcaaacaata
    23821 tgcaaagttt gtttttgaat gtaagcttct cgatggacaa ttccaagaaa atcaagaaat
    23881 cgctgacctt caattttttg caattgacca actgccgaat ttatctgaaa aacgcattac
    23941 caaggagcaa atcgagattc tttggcaggt ttatcaaggt cagagggagc aatatcttga
    24001 ctaagaagat gattatcgta tttctaaatt catttttctt aagtagcatg gtataataaa
    24061 atgcaggaaa attttgaatc atgaggaaga ctagatgaat ttatgggata ttttctttac
    24121 gactcaggca accgagccgc ccaaatttga ccttttttgg tatgttagcc tatttacgct
    24181 cttagcctta accttttata cagcccatcg ctatcgtgaa aagaaggttt accaacgatt
    24241 tttccaaatc ttgcagactg ttcagttaat ccttctttat ggttggtact gggtcaatca
    24301 tatgccactg tcagaaagcc taccctttta ccattgccgt atggctatgt ttgtggtact
    24361 cttgcttcct ggtcagtcca aatataaaca atactttgca ttattgggaa catttgggac
    24421 attagcagcc tttgtttatc cagtgccaga tgcttaccct tttccacata tcaccattct
    24481 atcctttatc tttggtcatt tagcactctt ggggaactct ctagtttatc tattgagaca
    24541 gtataatgcg cgattgctgg atgtgaaggg aatttttctc atgacctttg ccctaaatgc
    24601 cttgattttt gtggtcaatt tggtgacagg tggcgattac ggatttttga caaaaccgcc
    24661 attggttggg gatcacggtc tagtagctaa ttatttactt gtttcaattg tgctggtagc
    24721 tactatcagt ttgactaaga aaatcttaga attcttttta gctcaagaag cagaaaaaat
    24781 gattgcaaag gaagcttaac acagagcttt cttttttgct cttagagagt ttttacaagc
    24841 agcttataaa ataagaattt ctgaatagac aaactcaaaa aatggctggg aaatttagga
    24901 aaaaagcaag cacgattaaa ttttttgtgt tataatattt tgtgaatagc tatgcctatg
    24961 tttagctatg gaataatacg aagtgcgaaa cttggaagat agagaggaag cgatgtaatg
    25021 gctagagaag gcttttttac aggtctagat attggaacaa gctctgtcaa ggtgcttgtg
    25081 gccgagcaga gaaatggtga attaaatgta attggcgtga gtaatgccaa aagtaaaggt
    25141 gtaaaggatg gaattattgt tgatattgat gcagcagcaa ctgctatcaa gtcagccatt
    25201 tcccaagcgg aagaaaaggc aggcatttcg attaaatcag tgaatgtcgg cttgcctggt
    25261 aatcttttgc aggtagaacc aactcagggg atgattccag taacatctga tactaaggaa
    25321 attacggatc aagatgttga aaatgttgtc aaatcagctt tgacaaagag tatgacacct
    25381 gaccgtgaag tcattacctt tattcctgaa gaatttattg tggatggttt ccaagggatt
    25441 cgtgacccac gtggcatgat gggggttcgc cttgaaatgc gtggtttgct ttatacagga
    25501 cctcgtacta tcttgcacaa tttgcgtaag acggttgagc gtgcaggtgt tcaggttgaa
    25561 aatgttatca tttcaccact agcaatggtt cagtctgttt tgaacgaagg ggaacgtgaa
    25621 tttggtgcta cagtgattga tatgggggca ggtcaaacga ctgtcgctac aatccgtaat
    25681 caagaactcc agttcacaca tattctccaa gaaggtggag attatgtaac taaagatatc
    25741 tccaaggttt tgaaaacctc tcgcaaatta gcggaaggct tgaaactgaa ttacggggaa
    25801 gcctatccgc ctcttgcaag caaagaaacc ttccaagtag aggttattgg agaagtagaa
    25861 gcagtcgaag tgacggaagc ctacttgtca gaaattattt ctgcacgaat caagcacatc
    25921 cttgaacaaa tcaagcaaga attagataga aggcgtctat tggacctccc tggtggtatt
    25981 gtcttaatcg gtgggaatgc cattttacca ggtatggttg agcttgctca ggaagtcttt
    26041 ggcgtccgtg tcaagcttta tgttccaaat caagttggta tccgtaatcc agcctttgcg
    26101 catgtgatta gtttatcaga atttgcgggt caattaacag aagttaatct tttggctcag
    26161 ggagcgataa aaggtgagaa tgacttaagt catcagccaa ttagttttgg tgggatgctg
    26221 caaaaaacag ctcagtttgt acaatcaacg cctgttcaac cagctcctgc tccagaagta
    26281 gagccggtgg cgcctacaga accaatggcg gatttccaac aagcttcaca aaataaaccg
    26341 aaattagcag atcgtttccg tggattgatc ggaagcatgt ttgacgaata aagaggaaaa
    26401 ataaattatg acattttcat ttgatacagc tgctgctcaa ggggcagtga ttaaagtaat
    26461 tggtgtcggt ggaggtggtg gcaatgccat caaccgtatg gtcgacgaag gtgttacagg
    26521 cgtagaattt atcgcagcaa acacagatgt acaagcattg agtagtacaa aagctgagac
    26581 tgttattcag ttgggaccta aattgactcg tggtttgggt gcaggaggtc aacctgaggt
    26641 tggtcgtaaa gccgctgaag aaagcgaaga aacactgacg gaagctatta gtggtgccga
    26701 tatggtcttc atcactgctg gtatgggagg aggctctgga actggagctg ctcctgttat
    26761 tgctcgtatc gccaaagatt taggtgcgct tacagttggt gttgtaacac gtccctttgg
    26821 ttttgaagga agtaagcgtg gacaatttgc tgtagaagga atcaatcaac ttcgtgagca
    26881 tgtagacact ctattgatta tctcaaacaa caatttgctt gaaattgttg ataagaaaac
    26941 accgcttttg gaggctctta gcgaagcgga taacgttctt cgtcaaggtg ttcaagggat
    27001 taccgatttg attaccaatc caggattgat taaccttgac tttgccgatg tgaaaacggt
    27061 aatggcaaac aaagggaatg ctcttatggg tattggtatc ggtagtggag aagaacgtgt
    27121 ggtagaagcg gcacgtaagg caatctattc accacttctt gaaacaacta ttgacggtgc
    27181 tgaggatgtt atcgtcaacg ttactggtgg tcttgactta accttgattg aggcagaaga
    27241 ggcttcacaa attgtgaacc aggcagcagg tcaaggagtg aacatctggc tcggtacttc
    27301 aattgatgaa agtatgcgtg atgaaattcg tgtaacagtt gttgcaacgg gtgttcgtca
    27361 agaccgcgta gaaaaggttg tggctccaca agctagatct gctactaact accgtgagac
    27421 agtgaaacca gctcattcac atggctttga tcgtcatttt gatatggcag aaacagttga
    27481 attgccaaaa caaaatccac gtcgtttgga accaactcag gtatctgctt ttggtgattg
    27541 ggatcttcgc cgtgaatcga ttgttcgtac aacagattca gtcgtttctc cagtcgagcg
    27601 ctttgaagcc ccaatttcac aagatgaaga tgaattggat acacctccat ttttcaaaaa
    27661 tcgttaagta aatgaatgta aaagaaaata cagaacttgt ttttcgagaa gttgcagagg
    27721 ctagtctgag tgctcatcga gagagtggtt cggtctctgt cattgcagtt accaagtatg
    27781 tagatgtacc gacagcggaa gccttgcttc cgctaggtgt tcatcatatc ggtgaaaatc
    27841 gtgtagataa gtttctggaa aaatatgaag ctttaaaaga tcgagatgtg acttggcatt
    27901 tgattggtac cttgcaaaga cgtaaggtga aagatatcat tcaatacgtt gattatttcc
    27961 atgcattgga ctcagtaaag ctagcagggg aaattcaaaa aagaagtgac cgagtcatca
    28021 agtgtttcct tcaagtaaat atttctaaag aagaaagcaa acacggtttt tcgagagagg
    28081 aactgctgga aatcttgcca gagttagcca gactagataa gattgaatat gttggtttaa
    28141 tgacgatggc accttttgag gctagcagtg agcagttgaa agagattttc aaggcgaccc
    28201 aagatttaca aagagaaatt caagagaaac aaattccaaa tatgcctatg accgagttaa
    28261 gtatgggaat gagtcgtgat tataaagaag cgattcaatt cggttccact tttgttcgta
    28321 taggtacatc attttttaag taggagagaa ccatgtcttt aaaagataga ttcgatagat
    28381 ttatagatta ttttacggag gatgaggatt caagtctccc ttatgaaaaa agagatgagc
    28441 ctgtgtttac tccagtaaat tcttcacagg aaccggctct cccaatgaat caaccttcac
    28501 agtcggctgg tacaaaagag aacaatatca ccagacttca tgcaagacaa caggaattgg
    28561 caaatcagag tcagcgtgca acggataagg tcattataga tgttcgttat cctagaaaat
    28621 atgaggatgc aacagaaatt gttgatttat tggcaggaaa cgaaagtatc ttgattgatt
    28681 ttcagtatat gacagaggtg caggctcgtc gttgtttgga ctatttggat ggagcttgtc
    28741 atgttttagc tggaaatttg aaaaaggtag cttctaccat gtatttgttg acaccagtga
    28801 acgttattgt aaatgttgaa gatatccgtt taccagatga agatcaacag ggtgagttcg
    28861 gttttgatat gaagcgaaat agagtacgat aatgattttt ttaattcgta tgatttataa
    28921 tgcagtggat atttactccc tgattttggt agccttcgct gtcatgtctt ggtttccagg
    28981 tgcctatgaa tccagtttag gtcgttggat tgtagcgttg gtaaaaccag tgcttgctcc
    29041 cttgcaacgc ctgcctttac agatagcggg tcttgattta tctgtttggg ttgcgattgt
    29101 tttggttcga tttttaggag aaaacctagt gcgttttctg gcgatgatag gatgaataaa
    29161 gggatttatc agcatttctc catagaagat cgtccatttc ttgacaaggg aatggaatgg
    29221 ataaagaagg tagaagatag ctatgctcct tttttaactc cttttatcaa tcctcatcag
    29281 gagaagctat taaagatttt ggccaaaacc tatggtcttg cttgtagcag tagtggggaa
    29341 tttgtctcga gtgagtatgt tcgagtttta ttatacccag attatttcca accagagttt
    29401 tcagattttg aaatatctct tcaggaaatt gtgtattcca ataaatttga acatttaacg
    29461 catgctaaga ttttagggac agtcatcaat caattaggga ttgaacggaa actttttgga
    29521 gatatcctag tagatgaaga gcgggcgcag attatgatta atcagcagtt tcttcttctc
    29581 tttcaagatg gattaaagaa aattggtcgt atacctgttt cgctggagga acgtcctctc
    29641 gccgagaaaa tagataagct agaacagtat cgagaactgg atttatctgt gtctagtttt
    29701 cgattagatg ttcttttatc aaatgttttg aaactatcta ggaatcaagc aaaccagttg
    29761 attgaaaaga aacttgtcca agtaaattat catgtggtag acaaatcaga ttatactgtt
    29821 caagttggag atttgattag tgtgagaaaa tttggtcgct tgaaattact tcaagataag
    29881 ggacaaacga aaaaagagaa gaaaaaaata accgtccagt tattattaag taagtgagga
    29941 atagaatgcc aattacatca ttagaaataa aggacaaaac ctttggaact cgattcagag
    30001 gttttgatcc agaagaagtc gatgaatttt tagatattgt ggttcgtgat tacgaagatc
    30061 ttgttcgtgc aaatcatgat aaagatttgc gtattaagag tttagaagag cgtttgtctt
    30121 actttgacga aatgaaagat tcattgagcc agtctgtatt aattgcccag gatacagcgg
    30181 agagagtgaa acaggcagcg catgaacgtt caaataatat cattcatcaa gcagagcaag
    30241 atgcccagcg cttgttggaa gaagctaagt acaaggcaaa cgagattctt cgtcaagcaa
    30301 ctgataatgc taagaaagtt gctgttgaaa cagaagaatt gaagaacaag agccgtgtct
    30361 tccaccaacg tctcaaatct acaattgaga gtcagttggc tattgttgaa tcttcagatt
    30421 gggaagatat tcttcgccca acagctattt atcttcaaac cagtgatgaa gcctttaaag
    30481 aagtggttag cgaggtcttg ggtgagtctg tgttacagca acatccagag gaagaaccaa
    30541 ttgatatgac acgtcagttc tctcaagtag aaatggcaga attacaggct cgtattgagg
    30601 cagccaataa agaattggct gaatttgaag ctcagactaa acaggaagtg gaagctccaa
    30661 ctcctgtagt gagtcctcaa attgaagaag aacctactca accagttggt ccaatgtatg
    30721 aagaaccaga agtagctcca gtatatcctt cagcttcaac accagctaca gaaactgttg
    30781 attcagcacc aggatttgaa gcaccgcaag aatctgttac aattttataa gaaatattct
    30841 gagaacaata tcttatcctt atatttccag cgagcaggag atggtgtgag tcctgtaatc
    30901 cctaacgata agattatcct ctcaaaaact caagtctgaa gttagtagga tttgacgttc
    30961 cccacgttac gggataagag ggagaaagac tagatctttt tccgaataaa ggtggtacca
    31021 cgattttcgt cctttttgga agtcgtggtt tttaatttgt tattatttat aaaggagata
    31081 ccatgaaact caaagatacc cttaatcttg ggaaaacagc ttttccaatg cgtgcaggcc
    31141 ttcctaccaa agagccagtt tggcaaaagg aatgggaaga tgcaaaactt tatcaacgtc
    31201 gtcaagaact aaatgaaggg aaaccgcatt ttgtcttgca tgatggccct ccatacgcaa
    31261 acggaaatat ccacgttgga catgccatga atcatatctc aaaagatatc atcattcgtt
    31321 ctaagtctat gtcaggtttt aactcacctt atatcccggg ttgggatact catggtctgc
    31381 caatcgagca agttttggca aagcaaggtg ttaagcgcaa agaaatggac ttggttgagt
    31441 acttgaaact ttgtcgtgag tacgctcttt ctcaagttta taaacaacgt gatgatttca
    31501 agcgcttggg gatgtcaggt gactgggaaa atttatatgt gactttaact ccagactacg
    31561 aagcagccca aatccgtgta tttggtgaga tggctaataa aggctatatc taccgtggtg
    31621 caaaaccagt ttactggtct tggtcatctg agtcagccct tgctgaagcg gaaattgaat
    31681 accatgattt ggtttcaact tccctttact atgccaataa ggtaaaagat ggcaaaggtg
    31741 ttctagatac agatacttat atcgttgttt ggacaactac tccatttact attacagctt
    31801 ctcgtggttt gactgttggt gcagatattg attacgtttt ggttcaacct gctggtgaaa
    31861 ctcgtaagtt tgtggttgct gcagaattgt tgattagctt gtctgagaaa tttggttggg
    31921 ctgatgttca agtgttggca acttaccgtg gtcaagaact caaccacatc gtaacagaac
    31981 acccatggga tacagttgta gatgagttgg ttatccttgg tgaccacgtt acaactgact
    32041 ctggtactgg tattgtccat acagcccctg gttttggtga ggatgactac aatgttggta
    32101 ttgctaatgg tcttgaagtc gcagtgactg ttgacgaacg tggtatcatg atgaagaatg
    32161 ctggtcctga gtttgaaggt caattctatg aaaaggtggt tccaactgtt attgaaaaac
    32221 ttggtaacct ccttcttgct caagaagaaa tctctcactc atacccattt gactggcgta
    32281 ccaagaaacc aattatctgg cgtgcagtac cacagtggtt cgcctctgtt tcaaaattcc
    32341 gccaagaaat cttggatgct attgataaag ttaaattcca tacagaatgg gggaaagtac
    32401 gtctatataa tatgattcgt gaccgtggtg actgggttat ctctcgtcaa cgtgcttggg
    32461 gtgttccact tccaatcttc tatgcagaag acggtacagc tatcatgaca gctgaaacga
    32521 ttgaacacgt agctcaactc tttgaagtac atggttcaag catttggtgg gaacgtgata
    32581 ccaaagacct cttgccagaa ggatttacac atccaggttc tccaaatggg gagttcaaga
    32641 aagaaacaga tattatggat gtatggtttg actcaggttc atcatggaat ggtgttttgg
    32701 taaatcgtcc aaatctgact tatccagctg acctttacct tgaaggttct gaccaatacc
    32761 gtggttggtt caactcatca ctcattacat ctgttgccaa ccatggcgta gcaccttaca
    32821 aacaaatctt gtcacaaggt tttgcccttg atggtaaagg tgagaagatg tctaaatctc
    32881 ttggaaatac cattgctcca agcgatgttg aaaaacaatt tggtgctgaa atcttgcgtc
    32941 tctgggtaac aagtgttgac tcaagcaacg acgtacgtat ctctatggat atcttgagcc
    33001 aagtctctga aacttaccgt aaaatccgta acacccttcg tttcttgatt gccaatacat
    33061 ctgactttaa cccagctcaa gacgcagtag catacgaaga gcttcgctca gttgataagt
    33121 acatgactat tcgctttaac cagcttgtca agaccattcg tgatgcttac gcaaactttg
    33181 aattcttgac aatctacaag gccttggtga actttatcaa cgttgacttg tcagcctttt
    33241 accttgattt tgctaaggac gttgtttaca tcgaaggtgc taaatcattg gaacgccgtc
    33301 aaatgcagac tgtcttctat gacattcttg tgaaaatcac gaaactcttg actccaatcc
    33361 ttcctcacac tgcggaagaa atctggtcat atcttgagtt tgaagccgaa gacttcgttc
    33421 aattgtcaga attgccagaa gcggaaactt ttgctaatca agaagaaatc ttggatacat
    33481 gggcagcctt catggacttc cgtggacaag ctcaaaaagc cttggaagaa gctcgtaatg
    33541 caaaagtaat cggtaaatca cttgaagcac acttgacagt ttatccaaac gaagttgtga
    33601 aaactctact cgaagcagta aacagcaatg tggcccaact tttgatcgtg tctgagttga
    33661 ccatggcaga gggaccagct ccggaagctg cccttagctt cgaagatgta gccttcacag
    33721 ttgaacgtgc tgctggtgaa gtatgtgacc gttgccgtcg tatcgaccca acaacagcag
    33781 aacgcagcta ccaggcagtt atctgtgacc actgtgcaag catcgtagaa gaaaattttg
    33841 cggaagcagt cgcaggagga tttgaagaga aataagatga aaagtctcta tgcgtctagt
    33901 atataaaaat gagttattcc aagtttataa tctctcttgt gagatgctaa agtttgatga
    33961 gaattggttt tgctaatatt aggagaaagt aagtatgcta aaattgcaag attgtttttc
    34021 ttgcgattgt ttaaactagt gaggaaaaat aaacattatg agacaaacaa atgttagagg
    34081 aagcttgtcc ctccgtggct ttagaaaatt aagaactggt gcaattgttg cgacaggtgt
    34141 gattctactg gggctgggct tttcagctcc aactgcgtca gtcagtgaac aagatggtgt
    34201 ttgggtagcc agaacagttg cagaagtaaa agctgatatt caaaaagaag gtgatttatt
    34261 taagtatgtc attaagtggg gagatacatt aagtgttatc agcgaagcaa gcaatatccc
    34321 tgtagatgta ctccaagaaa tgaatcaagc ttcaggcaag aatttattct taccatacaa
    34381 tgaattgtac tttactgaag ctgaaacagt ttcagataca gtcacaaaac acaagattgt
    34441 catcaaagaa agtggtgcaa gtggcgaagt tcgcacttat gaggtcttgc tcaagaaaga
    34501 ccaagaaaca aaagctgtta cctttgaatt aacagatgtc actgagaaag ttgaaaaaat
    34561 gactgtgaac tatagcccag tttatcagcc tgtatcagta ccagtagtgg aaagagcgga
    34621 agaatcagtt gaagagcctg ccctagtagc accagctgtg acaagcccag aagttaaaga
    34681 agaaacagaa gatccagtag tactaaaagc agaagaagca gcgactaccc cagcaacgaa
    34741 agaaacagca ccagaggtgg taacaccagc tgaaccaaac gcagaaaccc cagcgccgaa
    34801 agtagaagcg ccaacagaat catctgaacc aaaaggaaca gagccagagg tagccaaacc
    34861 agctggagat tcagtatcat ctacaagtga gtcaaatgag gatggcaatt caggcgattc
    34921 aactcattca acattgacct ctgatgaaac aaaaccagaa gaggtagaat caacttcagt
    34981 aacggacaat gtcccttcaa atgcagggac aacaaatcaa cctctaaccc caacatctaa
    35041 ttctgatgat tcagcaccaa aagaagtagc aaatggaact gaaggaaaag tagaagcgcc
    35101 gaaagttgaa gaagcagtat cagaaggaga agaaggtaac gccgaaataa caaataatcc
    35161 atcaacaggc gctactcctt caagtgatga aacgacagaa caatctggaa ctccagctcc
    35221 aaaaccagaa gaggaagctc cagtagcgac agaaacctca gcggcatcag ctgaatcaac
    35281 agaatcagca ccagtggtag caaaaccagc tgagccaaaa gcagaaacac cagaagcaac
    35341 aattacagga gatgaaggaa aagaatctga agaatcagga acatctgcaa ctgtggaatc
    35401 aacaccagca ggagaagaag gaaaagcgga ggattcagtt tcttcaactg aatcttcatc
    35461 aactgcttct gaaggggagt caacagctac gcaaccagct gtagaagcag gaacagattc
    35521 aacatcggaa gctgaagaac ttgcaactac ggaaacagca acaacgccga aaacggaaga
    35581 gccagaagcg gtagccccag ctccagaagc accctcagaa tcagactcga aagaagaaga
    35641 ttcagctgca ggggatacaa cagttacaga agaacagcca gctgcagaaa ctgtctctga
    35701 aggtggatca ccagctacgc aaccggctgg agaagaaggt aaatctgaaa aagaaccgaa
    35761 agtagaaggg caaccatcag gtacagagtc ggcaacccca gaacagcata caaatattga
    35821 ggaaacaaca gaaaagcaat cgggggctac atcagaaaat tcaggtgata gtctagtatc
    35881 agatgagcca gctgcgagct caggtatttc aacatcttca ggaacagaag gggcagaaac
    35941 gatagataca gaaacaattg cagaaaaatc agaaataccg tctccagcag aagaaggatc
    36001 tgctaaagaa gaaaaagaag ttattaagaa actagaactt agaaatatat cttctgttga
    36061 actatattct aaagaaggtg ataagtatcg tcatgtaact tcacttgcta ccttaccaag
    36121 taatccagag acttacttta tgaaagttaa atcagagaac tttaaagatg ttatgctacc
    36181 agttacaagc attactaatg ataataaaga taatagagat gtttataaaa tagtagcaag
    36241 tgtaaagaat ctgatacagc atgaaaataa taaagtacta gagaattata catactattt
    36301 atcaaaaact cagcaaggtg aaactggagt atatacatca tttaaaaatt tagttgatgc
    36361 gatgaataga gattcttatg gagagtttcg tttaggtgca actatggatg ctcgtgaagt
    36421 tgaacttcca gatggtcaag aaagttatgt gaagaatgta tttcacggta gactaatagg
    36481 tcaaaatagt aataagtatt atgctatata taatttgaaa aagccattat ttaatgcttt
    36541 aagtaatgct agagtacaaa atctttcact aaaagatgtt aatatttccg caaaggacga
    36601 tactgcaaca ctagcgaaag aagcaaataa caatactcat attgataatg ttcattctga
    36661 tggagcgata gccggggaac gtagcatagg aggattagta tcacaagtta ataattctac
    36721 tatttctaat agtagctata ctggtagaat aactaataca tataaaacag ttgctagtta
    36781 tcaaatcgga ggtttagtag gtaaactttc tggtccgaat ggtttaattg ataaatcgat
    36841 agcatcaata gatttggctt caaacgcaac acgaggtgat cagtctattg gtggaatagc
    36901 tggttcagta attgataatg cagtgataag tagtagttat gctgaaggga aattaaataa
    36961 tgttcaacct tttgcaaatg ttggtggagt agttggtgac ctttgggatc cagtaggcgg
    37021 attggaaaaa tctggtcaac tatctaatgt actaagtgat gttaatgtta caaacggtaa
    37081 tgctatcgcg ggtaaacatt ttgatcacat gaaagcaact aatgtttata gtaataaaaa
    37141 taataaggtt gtgaacgtag tacaagaaaa tgatgaaatt ttaactaagg attctgttgt
    37201 tcaaagagga gaagtattag aagatgaaca aataaaagag aaaaaagctg cttttgttac
    37261 taaaaatact gttaaaacag aagattttaa tttctcttca agatatgtaa ctgactataa
    37321 aaatcttgag aatgctgatt cgtcaaaaga aaaagtatat aaaaatattg aaaaactatt
    37381 accattttat aatagcgaaa caatagtgaa gtatgggaat ttagtagaga caagtagtaa
    37441 tctttataat aaagaattat tgtcagttgt tcctatgaaa gataaagaag taattagtga
    37501 tattaataaa aataaatcaa gcataaataa attattactg tattatgcgg ataattcgta
    37561 tgagacatta aatgtaaatt atcaaagtga tttttctaat gtagcagagt atagcatagg
    37621 cggtacaaat ttaatttata caccgaatac attacttcgc gattacaata atatattaga
    37681 tggagtatta cctgtattag aaactgtgga ttataagtca gacgcaatta gaaaagtatt
    37741 agatgtttct aatgatgtta gcttaacgga gttatattta gaagaacaat tcaatactac
    37801 taaaaataat ttgagagata gtctaacaaa actgcttact gcagatgctg caatatctga
    37861 aaatagtaat tcaataattg ataattatgt aatagaaaaa attaagaata ataaagaagc
    37921 gttacttcta ggattaacat atttagagcg ttggtacaat ttcaaatatg gtgaaacaaa
    37981 agcgaaagat ttagtgatgt accacttgga tttctttggt aaatcaaata gttcagctct
    38041 agataatgtt attgaactag gtaaatctgg atttaataat ttattagcta agaataatgt
    38101 tattacttat aatgtattgt tatcgaaaaa ttataaaact aataatttat ttgatgcatt
    38161 agaaaaatat agaaaagttt ttgtgccaga taaaacaaat aacgaatggt ttaaagaaca
    38221 aactaaagct tatatagtgg aagaaaaatc tacaattaaa gaggtaaatg ataaacaatc
    38281 aaaagcaggt actccgcaat ctataggggt gtatgataga ttaaccagcc catcttggaa
    38341 atacccaagt atggtattgc cgctattaac attacctgaa aaatcggtgt ttatcatagc
    38401 gaacatttca acaataggat ttggcgctta tgatagatat agaagtaaag aacatccagc
    38461 aggaactaat ttaaatgact atgttgaggc aaaagctaga gaagcggctg ttagatttag
    38521 agatcactat gattactggt ataaaattct agataataat aataaagaaa aattatatag
    38581 aagtgtccta gtctatgatg catttagatt cggtgcagat gataagggag aaagagaaac
    38641 aaaacaagct aattttgaaa ctgatcatcc agcaataaaa cacttcttcg gtccagcagg
    38701 aaataatgtt gttcataatt ctaatggagc atatgctaca ggtgacgcat tctactatat
    38761 ggcttatcgt atgcttgata aagatggtgc ggtaacttat acacatgaaa tgacacataa
    38821 ctcagataga gaaatttatc ttggaggcta tggaagacga aatggacttg gaccagagtt
    38881 ttatgcaaaa ggattgttac aagctcctga tcatcctgat gatcctacta ttacgattaa
    38941 ctcaatattg aaatatgaag aatcagaaga tccaactaga cttcaggtaa aagatcctac
    39001 aaaacgattt aataatgcag aagacttgca aaaatatatg tataatatgt ttgatgtaat
    39061 ttatatgcta gaatatctag aaggtaatgc agttgttaaa ttagatattt ctaagaaaaa
    39121 tgagttgttg agaaaaatag aaaataaatt tgaaacagat ccagatggaa gtaatgtcta
    39181 tgcaactaat gttgttcgtt atttaaaacc tgaagagctt actaaattaa cttcatttaa
    39241 tagtttaatt gaaaatgatg ttattactag aagaggatac gaaaatggaa atgacaatac
    39301 ttttaaacga aatggatatt atacaattaa actattttca ccaatatatt cagctttaag
    39361 taataatgaa ggaactccgg gagatttaat gggtcgtcgt atggcatttg aactgttggc
    39421 tgcaaaagga tttaaagatg gaatggtacc atatatttct aatcaatatg cagaagaagc
    39481 gaaagctaaa ggtaaagtga ttaagtcata tggtaaggaa gttggtaatg taactgatga
    39541 gttagtactt caaaaaatat ttaataatcg ttactcatct tgggtagaat ttaaaaaagc
    39601 aatgtataat gaaagaatag ctaaatttaa aaaattaatg agcattagct tcgataaccc
    39661 aaatggaaat tggttcagaa aagatagagt gacaataaaa aatatagaag atcttcaaag
    39721 aatgataact actgctgtca atgaagatgc tgaggattat cttgtgaaca tatatccaga
    39781 aagaagtaga gttcttaaac tgaaaaaagc aatctttaaa gcttatcttg atcaaacaaa
    39841 tgattttaga agttcaattt ttgatgagga aaaataaatt tactaattag gggtagcaca
    39901 tgaagatagg tttcgtttct tcatgtgtga aactctttcc tttttggttt tgactagctt
    39961 ttttgtgaaa aattgtgtaa aatagaatag ataaacgagg ggaaacctcg gaaaatttaa
    40021 aggagaatcc atctaatggt aaaattggtt tttgctcgcc acggtgagtc tgaatggaat
    40081 aaagctaacc ttttcactgg ttgggctgat gttgatttgt ctgaaaaagg tacacaacaa
    40141 gcgattgacg ctggtaaatt gatcaaagaa gctggtatcg aatttgacca agcttacacc
    40201 tcagtattga aacgtgcgat taaaacaaca aacttggctc ttgaagcttc tgaccaattg
    40261 tgggttccag ttgaaaaatc atggcgtttg aacgaacgtc actacggtgg tttgactggt
    40321 aaaaacaaag ctgaagctgc tgagcaattt ggtgatgagc aagttcacat ctggcgtcgt
    40381 tcatatgatg tattgcctcc aaacatggac cgtgatgatg agcactcagc tcacactgat
    40441 cgtcgttacg cttcacttga cgactcagtt atcccagatg ctgaaaactt gaaagtgact
    40501 ttggaacgtg cccttccatt ctgggaagat aaaatcgctc cagctcttaa agatggtaaa
    40561 aacgtattcg taggagctca cggtaactca atccgtgctc ttgtaaaaca catcaaaggt
    40621 ttgtcagatg acgagatcat ggacgtggaa atccctaact tcccaccatt ggtattcgaa
    40681 ttcgacgaaa aattgaacgt agtttctgaa tactaccttg gaaaataaaa aattgtaagt
    40741 ctagaattga tttctaggct ttttatgtgg ctctttgtca actgtagtgg gttgaagtca
    40801 g
//
LOCUS       DAVDZK010000018        37440 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVDZK010000018 DAVDZK010000000
VERSION     DAVDZK010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37440
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.019"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(161..631)
                     /locus_tag="VUX16_001076"
     CDS             complement(161..631)
                     /locus_tag="VUX16_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET8124054.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(648..2921)
                     /locus_tag="VUX16_001077"
     CDS             complement(648..2921)
                     /locus_tag="VUX16_001077"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET8124055.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELKVKLPHKIELEKPQLNLVQPQGQAVLIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            3285..6386
                     /locus_tag="VUX16_001078"
     CDS             3285..6386
                     /locus_tag="VUX16_001078"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET8124056.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDISLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDVSAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYLIDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            6469..7476
                     /gene="pfkA"
                     /locus_tag="VUX16_001079"
     CDS             6469..7476
                     /gene="pfkA"
                     /locus_tag="VUX16_001079"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET8124057.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            7535..9040
                     /gene="pyk"
                     /locus_tag="VUX16_001080"
     CDS             7535..9040
                     /gene="pyk"
                     /locus_tag="VUX16_001080"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET8124058.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(9730..9955)
                     /locus_tag="VUX16_001081"
                     /pseudo
     CDS             complement(9730..9955)
                     /locus_tag="VUX16_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            10803..11675
                     /locus_tag="VUX16_001082"
     CDS             10803..11675
                     /locus_tag="VUX16_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET8124059.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQYATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(11821..12165)
                     /locus_tag="VUX16_001083"
                     /pseudo
     CDS             complement(11821..12165)
                     /locus_tag="VUX16_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            12308..12619
                     /locus_tag="VUX16_001084"
     CDS             12308..12619
                     /locus_tag="VUX16_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124060.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETAEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKYSI
                     K"
     gene            12623..13339
                     /locus_tag="VUX16_001085"
     CDS             12623..13339
                     /locus_tag="VUX16_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET8124061.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQVPKEIASLMNEWLAYFL"
     gene            complement(13468..14283)
                     /locus_tag="VUX16_001086"
     CDS             complement(13468..14283)
                     /locus_tag="VUX16_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET8124062.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKRVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHDNSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(14280..15185)
                     /locus_tag="VUX16_001087"
     CDS             complement(14280..15185)
                     /locus_tag="VUX16_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET8124063.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PEKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            complement(15605..15688)
                     /locus_tag="VUX16_001088"
                     /pseudo
     CDS             complement(15605..15688)
                     /locus_tag="VUX16_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            15732..17861
                     /locus_tag="VUX16_001089"
     CDS             15732..17861
                     /locus_tag="VUX16_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET8124064.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEVVLAKIQEQGKLTKELEEAILEAEKLADVEELY
                     LPYKEKRRTKANIAREAGLFPLARLILQNVADLEQEAEKFVCEGFATGKEALSGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQVKDESLDEKQVFQIYYDFSETVGNMQGYRT
                     LALNRGEKLGVLKVDFEHATDRILAFFAARFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASSESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            17848..18297
                     /locus_tag="VUX16_001090"
     CDS             17848..18297
                     /locus_tag="VUX16_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET8124065.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTKRYRCGLCRGKLLLVNQPED"
     gene            18356..18628
                     /locus_tag="VUX16_001091"
     CDS             18356..18628
                     /locus_tag="VUX16_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET8124066.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(18982..19173)
                     /locus_tag="VUX16_001092"
     CDS             complement(18982..19173)
                     /locus_tag="VUX16_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124067.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            19601..20359
                     /locus_tag="VUX16_001093"
     CDS             19601..20359
                     /locus_tag="VUX16_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124068.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPTRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            20361..22349
                     /locus_tag="VUX16_001094"
     CDS             20361..22349
                     /locus_tag="VUX16_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124069.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVTDPLTALTTFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTSDYNYLVVPNLQAFLDQFPDSAIYNQFYGGMNVSISEEEQLKVAEEYEKYLDQF
                     NAQLNTEGSYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQILTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     IDTTMMLIVTLSICAIFLIVYVLIFMITSRSYRKIVQM"
     gene            complement(22680..23375)
                     /locus_tag="VUX16_001095"
     CDS             complement(22680..23375)
                     /locus_tag="VUX16_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET8124070.1"
                     /translation="MSETNHEIDSNFAGRLNILRAGVLGANDGIISIAGVVIGVASAT
                     SNIWIIFLSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDMELAKKSL
                     YAAYIQNGECETSAQLLTNKAFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFL
                     GSLPPMLSITIFPSEYRIPATVLIVGVALLLTGYTSARLGKDPTKTAMIRNLAIGLLT
                     MGVTFLLGQLFSI"
     gene            24083..25543
                     /locus_tag="VUX16_001096"
     CDS             24083..25543
                     /locus_tag="VUX16_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET8124071.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILS
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENVRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADIAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDFLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKEN"
     gene            25544..26404
                     /gene="speE"
                     /locus_tag="VUX16_001097"
     CDS             25544..26404
                     /gene="speE"
                     /locus_tag="VUX16_001097"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET8124072.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMTVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GYTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQTFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTKYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            26401..27660
                     /locus_tag="VUX16_001098"
     CDS             26401..27660
                     /locus_tag="VUX16_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET8124073.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGQWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQDIVPIQFLKALLPAPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            27660..28787
                     /gene="nspC"
                     /locus_tag="VUX16_001099"
     CDS             27660..28787
                     /gene="nspC"
                     /locus_tag="VUX16_001099"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET8124074.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEITDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            28784..29869
                     /gene="aguA"
                     /locus_tag="VUX16_001100"
     CDS             28784..29869
                     /gene="aguA"
                     /locus_tag="VUX16_001100"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET8124075.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVTDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            29879..30754
                     /gene="aguB"
                     /locus_tag="VUX16_001101"
     CDS             29879..30754
                     /gene="aguB"
                     /locus_tag="VUX16_001101"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET8124076.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(30935..31744)
                     /locus_tag="VUX16_001102"
     CDS             complement(30935..31744)
                     /locus_tag="VUX16_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET8124077.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            32016..32237
                     /locus_tag="VUX16_001103"
     CDS             32016..32237
                     /locus_tag="VUX16_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET8124078.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            32291..32962
                     /locus_tag="VUX16_001104"
     CDS             32291..32962
                     /locus_tag="VUX16_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET8124079.1"
                     /translation="MKKRAIQILLVLSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLMESGVLLLAVIYLLVFAGKKTFHFKWQLRYFIYLLLGYITSYMSDFLFSYFISLSS
                     NQISLNETIEMIGRQELPYFLLIVCFIGPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(33014..33211)
                     /locus_tag="VUX16_001105"
                     /pseudo
     CDS             complement(33014..33211)
                     /locus_tag="VUX16_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            33204..34112
                     /locus_tag="VUX16_001106"
     CDS             33204..34112
                     /locus_tag="VUX16_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET8124080.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            34109..34570
                     /locus_tag="VUX16_001107"
     CDS             34109..34570
                     /locus_tag="VUX16_001107"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET8124081.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILSIAMLKEEINGN"
     gene            34560..35447
                     /locus_tag="VUX16_001108"
     CDS             34560..35447
                     /locus_tag="VUX16_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET8124082.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDIPLEIVYQDEDVVVVNKPQGIVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYNLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGSRKTLKGHGQFLHAKTLGFTHPRTGKTM
                     EFTADIPEIFKETLERLRK"
     gene            35450..37330
                     /gene="cbpE"
                     /locus_tag="VUX16_001109"
                     /gene_synonym="pce"
     CDS             35450..37330
                     /gene="cbpE"
                     /locus_tag="VUX16_001109"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET8124083.1"
                     /translation="MKKKLTSLVLAGAFLSLSWYGNVQAQESSGNKIHFINVHEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWRQGINTTYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYKNETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGSLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYVVGWNKIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSNSEIKESNQVVKKDLENKETNQHESVASSSSSQDLTSSTSQSSEINANKSE
                     SE"
BASE COUNT        11395 a         6747 c         8122 g        11176 t
ORIGIN      
        1 gttgacgcgg attgaagaga ttttcgaaga gtataaatct tcctaggata aagcaaaacg
       61 catagtatca agtgttgaaa acccttgata ctatgcgttt tctgatgtta aagactttct
      121 accagttttt ttaagcataa ttgttagttg tagtcattta ttattcttca aagaaaaatg
      181 gtggggcgaa ttttttcagt tcttcaaagc acttttgagc agtatctgca tcttcacaga
      241 tgataagaca gacatcatta ccacaaaggg tagcgatagc atcagggaag ctcaaagtat
      301 caatgataga accaaaggat tgagccagtc caggaagggt ttttagtagg acttggtgtt
      361 gaactgggcg catccagaca agggcgtctt ccatgtagag ttcgagacgt ttttcccatt
      421 ttgagatgga accattgtta agaacataat aagcgctatc ttcttcgcgg acttttgata
      481 ggttcatatt tttgatgtcg cgtgagaggg ttgcctgggt tacttgaatg tcgttcttag
      541 caagaagggc ttgcaactca gcctgtgtat gaatcttgtt ttttgtgata agagcgcgta
      601 taagttggtg gcggtgttct gatttattca taataatgta actcctttta gcaaggtaag
      661 gtaagcatgg actgagcgag gtcgacagtc aagtggtagt ctgtattgtc acggatggtg
      721 atttcaaagt cagtagtata gaggactaaa cggagagtgt ctccttcttt tagcttgtaa
      781 atagttggct gcagttcaaa ttgaacgtcc atccattcat ctgcagtaat atcctctact
      841 aacagtaaat catttctatt ttgtaaatta aggtaacctt ttgtcacgac tcgttgtgcc
      901 tctggtctaa atggcaattc acagagattt tccaacatgt gatagcgacc gttgtcaatg
      961 gttctagcac ttaaaatagc tggataaggt tgtaggtatt tcttttgccc aaattctagc
     1021 agttgggcag ataagagccc cttgtttgta ctggatttga tacgaagatt gagctgagcg
     1081 cgaccgttta ggtggagatc tttagtcaca ggaaggttaa tagtaatctg attagctttc
     1141 ccttgataga gctctgtatt gaaggtttgg tatgtcttac tatagcgctc aaaatcctta
     1201 tctgggtact ggttttgaat agcttgctct tcttgaccaa gtgagaaggt tttacagttt
     1261 tcttgcccac cgaagttatc aagtgataac caagtctgtg gagctgtatt gtcctgccag
     1321 ataacagtag gaagttgaaa gtctgtttcc tgtcctagta atttcttggt taataaggca
     1381 tttatggact cacggaagtc aattgattgc caattgttca tgtaaacatg ggcaccatta
     1441 tggaaaaaga gatgcttgtg tatatgagta ggaagagcat ggaacatctg gtaaacatga
     1501 agtggtttga cattccaatc ctgagaacca tgagtaaaga caacctctgc ctttacttta
     1561 tgggcattga gcagataatt gcggtcatgc caaaactgat tgtagtcccc agtttttcgg
     1621 tctagctgag ctttcacttt ttctaagtca gcttggtgag cttcattgcc acggatatag
     1681 tcgccagcta agagattacg agaataggtt aactcagcaa gggagtcaaa gtcctcacct
     1741 ggataaccac ctgggctagt caccagaccg ttttcacggt agtagttgta ccatgatgaa
     1801 attcctgcct cggcaatgat aacttctaaa ccatcgactc ctgtagtcgc aagaccattg
     1861 gacatggtac ctagatagga aagtcccgtt gtagcaactt ttccgtttga ccaatcagcc
     1921 ttgacttgac gctggcgcgt gtgatcagta aaggcacggc aacggccgtt aagccaatcg
     1981 atgacatttt tataagcctc gatttgctgg tagtctccat tagtcatgaa acctgtcgag
     2041 tctttggtac caacacctga gacatagaga ttggcaaagc ctctcggaag gaagtagtcg
     2101 tttagtgtat agctagagtt gatgtgagtt agcttttcct cagcctctgc tataagcaca
     2161 gcttgacctt ggggttggac gagatttagt tgaggtttct ctagctcaat cttgtgagga
     2221 agcttaacct taagctcgcc ctccatcttg tagagagcct tgtcactagc cttgtcattg
     2281 gttccctgat gataagggct ggctgtcatg atggcaggga tttttccatc aaaacgaggg
     2341 cgaataatgc taacctttac taggtctgat agcccttttt ggtcagtatc gacacgagac
     2401 tcaacgtaaa cgacttcacg aatgacatcc tggttagaaa aagtagccaa actcttgccg
     2461 ttaaagtagt ggtagtcatt atcctccgga ataagaccat cactaacaag ttggtcgata
     2521 agagtatttc cttttttggt gcgagtattg agtaactgat agagattttc aatcaagtca
     2581 ccatatataa tgggaaatcc agtttcttta cgaaaaacgt cactatcttc gaagtcaacc
     2641 aaataagaaa agcctaaaag ttgaaaagca acagtataaa aaatatctgc tgtcagttca
     2701 tcttctgatt gaaaaaatgt cagcaggtct gtttttttat cagctgctag gatagaaagt
     2761 gggtagttgg tgtcttgata agtgaaaaag aaacgacgta aaaaggtttc aagtgagtct
     2821 ttgtgattgg ctgtattttg taaatcaaag ccacattttt ttagttcaga taagacattt
     2881 tcttttggaa aattgatata actatattga ttaaaacgca tagaacctcc atatagaatg
     2941 acagttaagg ttattatatc aaaaaaaagc aattatatca aaaaaagcag aaagggaatt
     3001 gttaacttca aaaggaaata atccaataaa aatgaataaa gtactaaatt caatatagag
     3061 aacagagtaa caataagaat aaatagatag ggtataaaag ttctaggaga tttatattat
     3121 atgctttcta tttttatata caatatagta taaatataaa aatgatgaca aaaatacaaa
     3181 tgaatagaaa ataaattagt aagctgatga aatttttctc aagagaagcc atttataggt
     3241 gaaaatggta taatatagtg agaaggatag aggagaagtg taaattgatc gcacaactag
     3301 atacaaaaac agtctatagt tttatggaaa gcgtcatttc gatcgaaaag tatgtgagag
     3361 cagctaaaga atacggctac actcatttgg ctatgatgga tattgacaat ctttatggcg
     3421 ctttcgactt tctagagatt acaaaaaaat acggcattca tcctttgcta gggcttgaaa
     3481 tgacagtgtt tgtagatgat caggaagtga atttgcgctt tttagctcta tctagtgtgg
     3541 gctatcagca gttgatgaag ctttcgacag ccaagatgca gggggagaaa acttggtcag
     3601 tcctgtccca atacctggag gatatcgcgg tcattgtgcc ttattttgat agagttgagt
     3661 cgttagaact aggctgtgat tactatatag gggtttatcc agaaacacta gcaagcgaat
     3721 ttcatcatcc tatcttacct ctttatcggg tcaacgcttt tgaaagcagg gatagagaag
     3781 ttcttcaagt tttaacagcg attaaagaaa atctaccgct cagagaagtt cccttgcgtt
     3841 cgagacaaga tgtctttata tcagcaagtt ctttagagaa actattccaa gagcgttttc
     3901 cgcaagcttt ggacaattta gaaaagctta tttcaggcat ttcttacgac ttggatatta
     3961 gtctgaaact gcctcgtttt aatccagcta gaccagcagt agaggagttg agagagcgtg
     4021 ctgaactggg gcttgttcag aaggggttga ctagtaaaga atatcaagat agactagacc
     4081 aagaattgtc tgttattcat gatatgggct ttgatgatta tttcttggtt gtttgggatt
     4141 tgttgcgttt tggacgatcg aatggctatt atatgggaat gggaaggggt tctgcagtag
     4201 gcagtttggt ttcttatgcc ttagatatca cggggattga cccagtagag aaaaatctga
     4261 tttttgaacg ctttcttaat cgtgaacgct ataccatgcc tgatattgat attgatatcc
     4321 cagatattta tcgtccagat tttatcagat atgttggtaa taaatatggt agtaaacatg
     4381 cggcacaaat cgttactttt tcaacctttg gagccaagca agctcttcga gatgttttga
     4441 aacgctttgg tgtgccagag tatgaattat ctgcaattac taagaaaatc agttttcgtg
     4501 acaatcttaa gtcggcctat gagggcaatc tccagtttcg tcagcaaatc aatagtaagt
     4561 tagaatacca aaaagctttt gagattgctt gcaagataga gggctatcca aggcaaacct
     4621 ctgtccatgc ggctggtgtt gtaattagtg accaagattt aaccaactac attcctctaa
     4681 agtatggtga tgaaattcca ctgactcagt atgatgctca tggagttgag gctagcggac
     4741 ttttgaagat ggactttctg ggactacgaa atttgacctt tgtccagaag atgcaagagt
     4801 tgcttgctga aacagaaggt attcatctga aaattgaaga aatcgattta gaagacaaag
     4861 aaacgttagc tttatttgcc tctggtaata caaaaggtat ctttcaattt gagcaaccag
     4921 gtgccattcg tctgcttaag cgtgtgcaac cagtctgttt tgaagatgtc gtcgcgacta
     4981 cttctctaaa tcgaccgggt gctagtgact atatcaataa ttttgtggca agaaagcatg
     5041 ggcaggaaga agtgactgtt ctggatccag tactggagga tattttggct ccaacctacg
     5101 gcataatgct ctatcaggag caggttatgc aggttgccca gcgatttgcc ggatttagtc
     5161 ttgggaaagc cgatattttg cgtcgggcta tggggaaaaa ggatgtctct gccatgcatg
     5221 agatgagggc ttcctttatt caaggttcat tagaagctgg tcatactgtg gaaaaagcag
     5281 agcaggtctt tgatgttatg gagaagtttg caggctatgg ttttaacagg tcacacgcct
     5341 atgcctactc agcattggcc ttccagttgg cttattttaa aacacattat ccagccatat
     5401 tttatcagat tatgttgaat tctgccaaca gtgattactt aatagatgca cttgaagcag
     5461 gttttgaagt ggcgcctctg tccatcaaca cgattcccta tcacgataaa attgccaaca
     5521 aggccatcta tctaggtttg aaatccatta aaggagtcag taatgattta gctctctgga
     5581 ttattgaaaa tagaccttat tctaacattg aagattttat agctaaatta cctgagaatt
     5641 atctgaaact tcctctgcta gaacctttgg taaaagttgg tcttttcgat tcatttgaaa
     5701 aaaatcgtca aaaagtattt aataacttag ctaatctatt tgaatttgtg aaagagttgg
     5761 gaagtttgtt tggagatgct atttatagtt ggcaggaatc ggaagattgg acggaacaag
     5821 aaaaatttta tatggaacaa gagcttttag ggataggtgt cagcaaacat ccactacaag
     5881 ctattgcaag taaggctatt tacccgatta ccccaatcgg aaatttgtca gaaaatagct
     5941 atgctattat tttggttgaa gttcagaaaa taaaagtgat tcgtaccaaa aagggtgaaa
     6001 atatggcctt cttacaggca gatgatagta agaaaaaatt ggatgtcact ctcttttcag
     6061 acttatatcg tcaggtcgga caggaaataa aagagggagc cttctactat gtaaaaggaa
     6121 aaatacaatc acgtgatggc cgtctgcaaa tgattgcaca agaaataaga gaagcagttg
     6181 ctgaacgctt ttggatacag gtgaaaaatc atgaatcgga tcaagaaatt tcacgcattt
     6241 tagaacaatt taaaggccca atcccagtca tcatccggta tgaagaggaa cagaaaacta
     6301 tcgtttctcc ccatcatttt gtagctaaat ccaatgaatt agaggagaaa ttgaatgaaa
     6361 tcgttatgaa aacgatttat cgctaaaaat acggaaaata gaagaatttt aaaatcaaat
     6421 gtgatataat caagaagaat gttaaaagaa aaaggagcat aaaccaatat gaaacgtatt
     6481 gctgttttga ctagtggcgg agacgcacct ggtatgaacg ctgccatccg tgcagttgtt
     6541 cgtcaagcaa tttcagaagg aatggaagtg tttggtatct atgacggata tgctggtatg
     6601 gttgccggtg aaattcatcc cctagatgca gcttcagtag gggacatcat ttctcgtggt
     6661 ggtacttttc ttcactcagc tcgttatcca gagttcgctc aacttgaagg gcaacttaaa
     6721 gggattgagc aattgaaaaa acacggaatt gaaggtgtag ttgttatcgg tggtgacgga
     6781 tcttaccacg gcgctatgcg tttgactgaa catggcttcc cagctattgg tcttccaggt
     6841 acaatcgata acgatatcgt tggtactgac tttacaatcg gttttgacac agcggttact
     6901 actgccatgg acgctatcga taagattcgt gatacatcat caagtcaccg tcgtactttt
     6961 gtaatcgaag ttatgggacg taacgctggt gatatcgctc tttgggctgg tattgcaact
     7021 ggtgctgatg aaatcatcat ccctgaagca ggcttcaaga tggaagatat cgtagcaagc
     7081 atcaaagctg gttatgaatg tggtaaaaaa cacaatatca tcgtcttagc tgaaggtgtg
     7141 atgtcagcgg ctgaatttgg tcaaaaactt aaagaagctg gagatacaag cgaccttcgt
     7201 gtaacagaac ttggacatat tcaacgtggt ggttctccaa ctgcgcgtga ccgtgttttg
     7261 gcgtcacgta tgggtgcaca tgctgttaaa cttcttaaag aaggtatcgg tggtgttgcg
     7321 gttggtattc gtaacgaaaa aatggttgaa aatccaattc ttggtactgc agaagaaggg
     7381 gcattgttta gccttactgc agaaggtaag attgtggtta acaacccgca caaagccgat
     7441 attgagctat ctagcttgaa taagagcttg tcataattta caatttagtt aataagacca
     7501 aaaaggtcat atatataaag gagtcacaaa aatcatgaac aaacgtgtaa agatcgttgc
     7561 aactttgggt cctgcggtag aaatccgtgg tggtaaaaaa ttcggtgagg atggatactg
     7621 gggtgaaaaa cttgatgttg aagcttcagc taaaaacatt gctaaattga ttgaagctgg
     7681 tgctaacaca ttccgattca acttctcaca cggcgaccac caagaacaag gtgagcgtat
     7741 ggcaactgtt aaacttgcgg aaaaaattgc aggtaaaaaa gttggtttcc ttcttgatac
     7801 aaaaggacct gaaatccgta cagaattgtt cgaaggtgaa gctaaagaat attcatacaa
     7861 aactggtgaa aaaattcgtg ttgcaactaa acaaggaatc aaatcaactc gtgaagtgat
     7921 tgcgttgaac gttgctggtg ctcttgatat ctatgatgat gttgaagttg gtcgtcaagt
     7981 tttggttgac gatggtaaac ttggtcttcg tgtggttgct aaagatgatg caactcgtga
     8041 atttgaagtt gaagttgaaa acgatggtat catcgctaaa caaaaaggtg tgaacatccc
     8101 taacactaaa attcctttcc cagctcttgc tgaacgcgat aacgacgata tccgtttcgg
     8161 tcttgaacaa ggtatcaact tcatcgcaat ttcattcgta cgtactgcaa aagatgtgaa
     8221 cgaagttcgt gcaatctgtg aagaaactgg aaacggacat gttcaattgt tcgctaaaat
     8281 cgaaaaccaa caaggtatcg ataacttaga cgaaatcatc gaagcagctg atggtattat
     8341 gattgctcgt ggtgatatgg gtatcgaagt accgttcgaa atggttccag tttatcaaaa
     8401 aatgattatc aagaaagtca atgctgcagg taaagttgtt atcactgcaa caaacatgct
     8461 tgaaacaatg actgaaaaac cacgtgcaac tcgttcagaa gtatcagacg tattcaacgc
     8521 tgttatcgac ggaactgacg ctacaatgct gtcaggcgag tctgcaaacg gtaaataccc
     8581 actcgagtca gtaactacaa tggctacaat cgacaagaac gctcaagctc ttcttaatga
     8641 atacggacgt cttgattcag attcatttga gcgtaactct aagacagaag taatggcttc
     8701 tgctgttaaa gatgctacta gctcaatgga tatcaaattg gttgtaactc ttactaagac
     8761 aggtcatact gcacgtttga tttctaaata ccgtccaaat gctgacatct tagcattgac
     8821 atttgacgaa ttgacagaac gtggcttgat gttgaactgg ggtgttatcc caatgttgac
     8881 agatgctcca tcttcaactg acgatatgtt cgaaatcgct gaacgtaaag cggtagaagc
     8941 aggtctcgtt gagtcaggcg atgatatcgt tatcgttgct ggtgtgccag taggagaagc
     9001 tgttcgcaca aacacaatgc gtatccgcac agtacgttaa gaaaaatata aaaacctatc
     9061 atatccagct ttctagcctg tatgatgggc tctttttttg tccagggggc aaaaaggggg
     9121 caaaactttc ataatggatt gatactcttc gaaaatcaaa ttcaaaccac gtcagtgtcg
     9181 ccttaccgta ctcaagtaca gcttgcggct agcttcctag tttgctcttt gattttcatt
     9241 gagtatgaaa taagatatgc acaaattgat tagaaagtca aatgaatttc tacaaatgtt
     9301 ttagcaatcg taatgtactt gtctagattc gatctgatat attttcgatt taatgatatg
     9361 gtatttaaaa cctccaaagt agcttgctcc attcttttac ttacgtgagt gtagatgtta
     9421 tttactgttt tagcgttttt gtgttccact ctaaccatta tagcattctt ctcagctagt
     9481 gtactaagga gtgtgtgcct gaaaatatgg gaactaaggg gctggtttat cggtttctct
     9541 agtttagtat ttgccttttg caaagtgatg ttaaatgcct ttctctaaat ttacatatca
     9601 ctattgttta acaaaatcta atctatttta ggtcacttat tctttttttg aaatgtagaa
     9661 tgaacttttt caaagttttt cgaatctttt aaaatctgtt tgttttatat cgccattctc
     9721 cccccttttt taattctccc tatatagcct gacaactttc ccgatggtac gaatatggtt
     9781 gctttcgtct aggtggatgt cggggtattc gggattgagt ttttttgagg tagccttggc
     9841 ggagtttctt gacatagtta gcgccgtcta cttggaagat gccgatggta ttatagtcaa
     9901 tctgtggggt attcttgata aataggtagt cgctgtttct tatctttgcc tccatggact
     9961 tgctgacgac ataagcgatt gggtcgtagt cgtctgggat aatggaaact ccataactaa
    10021 atcgtcgtcc tgcatcgagc ggctacctgc agagataaac tacctaacac gagagtaagt
    10081 agtctgtctg tagtcgtcca gtctgatgat ttttacgata cttcgttttt ctgctcatac
    10141 agttgcctct aggcataggt taggacttta ccttgtctgg gtggtgcccg ttggtcgtag
    10201 atagattgga tatcgctagg agaatccttt tgaactggag gaaagagggc atcgatcaag
    10261 ctactgaata ctttaactaa gtcaaatata gtatttttct tagtagacct aacccttttt
    10321 tcataatttc taatggtgtt tttacttata cctatcttag tacccaattc ttattgagtc
    10381 caaccattac tagtctatat tgttttatag ttgattgagt ttggaatagt acgctgtagc
    10441 tgctaaaaca tttctaggaa ttaatttgcc tttcctaata gagttgttca tatcttattt
    10501 caatctatta tgtttttcac ctctaacaat cgcaatctct tctttatcca tgaatgaaat
    10561 cgctttctat ttttgtaagt aaagcataac acgaaatcca cgaaaatgaa aacctttgtt
    10621 gtgttttcgt aaaaaatttg ttgacagagc acgaaacgcc tactataatt aaatcaagct
    10681 taaggaaata acaaaaaaac aaatcggagg gaaagacgat gaacacatta aatgagaaag
    10741 taatcaatat ctgtaaagca gtagttaaag aaactttaat ccaagacatt taggagaaag
    10801 aaatgaagaa atcaagaaaa ttagccacat taggaatctg ttcagctttg tttttaggct
    10861 tggctgcttg tcaacaacaa tatgctactt ctgaggggac gaatcaaagg caaagcagtt
    10921 cagcgaaagt tccatggaaa gcttcataca ccaacctaaa caaccaggta agtacagaag
    10981 aggtcaaatc tctcttatca gctcacttgg atccaaatag tgttgatgca ttttttaatc
    11041 tcgttaatga ctataatacc attgtcggct caactggctt atcaggagat ttcacttcct
    11101 ttactcacac cgaatacgat gttgagaaaa tcagtcatct ctggaatcaa aagaagggcg
    11161 atttcgttgg gaccaactgc cgtatcaata gttattgtct tttgaaaaat tcagtcacca
    11221 ttccaaagct tgaaaagaat gaccagttgc ttttcctaga taatgatgca attgataaag
    11281 gaaaggtctt tgattcacaa gataaggaag agtttgatat tctattttcg agagttccaa
    11341 ctgaggcaac tacagatgtc aaggttcacg ctgaaaagat ggaaacattc ttctcacaat
    11401 ttcaattcaa tgaaaaagct cgaatgctgt ctgtagtctt gcacgacaat ctggatggcg
    11461 agtatctgtt tgtaggccac gttggggtct tagtacctgc tgatgacggt ttcttatttg
    11521 tagagaaatt gactttcgaa gagccctacc aagcgattaa atttgctagt aaggaagatt
    11581 gctacaagta tttgggcacc aagtatgcgg attatacagg cgagggactg gctaagcctt
    11641 ttatcatgga taatgataag tgggttaaac tttaatagtg ttatgatatg acagtaatct
    11701 taggattttt atttctattt ttgatgagtt ggtgggttat ttcaatcgtt aatagccaga
    11761 aaccacgcaa aaatgaaaca tttattggct atatccaaag atacgatatt gatgggaatg
    11821 gctatcaatc attaccgtgt cctcagaact gagaggagtt cttgaaaccg taaaaccgct
    11881 ttgaacaaga gttacttcaa cccattggct ccgacggagt aagttgcttt cgtgaatacc
    11941 aaaatcagcc gcaatttctt cataagttcg atattctcgc acatattgaa gagtggccat
    12001 aagaaggtct tctaggctta atttaggttt tcgtccccct tttgcgtgtt taagttgata
    12061 agctgttttt aatacagcta agatctcttc aaaagtggta cgctgaacac caacaagaca
    12121 tttaaatcgt gcatcagtta gttgtttact tgcttcataa ttcatagaac tactatacca
    12181 tattttgttt cgcaggaagt ctaatgctaa aatcttatca gtgagaagat ttcttaaagt
    12241 ttattctttg tagtttcatc tgtattagta cataatttaa cctagagaaa ataggaggac
    12301 taatcgaatg gaattaaaag attttacaga aaaagaacag gaaatgatta agaaaaggct
    12361 tacaatgtct aatattagtg acaaagaaac tgctgagaag attctggcgc tagtaccaca
    12421 agacttgatt aagcgaatcc cgttttttgt cagaaaacat gctacaacac gtacgattaa
    12481 acgcatttca attgaacacc ctgaactcta cgctgtagct caaacaagtg gtgagattcc
    12541 agaaaaagaa cgcgaagaat tgcgtcagat tatcacaact atctttgaac aaaagatgaa
    12601 taagtatagt attaagtaga gaatgaaaaa atattttatt ggcggtttgg gaagcaatgc
    12661 ctatcatagc aaggattttc ttcaagaact agattcgcag gtctattttc taaatccata
    12721 tgaaaagcat cttcgagatg aaacagaatt gaaatcatgg tttaaaaatg agattgtaga
    12781 ggaggaatct atctgtctga taggtcattc tcttggagga gatttagctc gttatttcgc
    12841 atcggaattt gaagaagtaa agaaactgat tcttttggat ggtggctatc tagatttaga
    12901 taagatttta cctttggata cagagttaga ggaaactaaa aattatatca aatctcaaat
    12961 tatttcggac ttagctcttc ttatttctaa agaaaaatct gaagcaaagc attggtcaga
    13021 aaatatggag aaagccgtaa gacaatccta tcactggaat gttgagtata atagatatga
    13081 gttggctata aattatgaaa atatagaagc gatactccgc ctacggagaa aaatacaagc
    13141 ttttaagaga gaagtgggag ataccttgtt tattagtcct cgctatccta atgaagctac
    13201 atggagagag gaagccctaa aagaattgcc agactatttt gatactattt ttttagaaaa
    13261 ctttggccat gagctttata ctcaagtgcc taaagaaatc gctagtctaa tgaatgagtg
    13321 gctcgcttat tttctatgag ctacttgtat tgctggaaat ggtataagat gaaaatctac
    13381 aagtcactaa ttttcatata acaaaaaacg aacaggctct ttttctgtta ttcagaagag
    13441 aacttgttcg tttttatctt gattttctta aaaagctcta tatacatagg gattttctgg
    13501 tttatcgact ttggtaaagc tgtcgatttc caaggttgga aggttttgtt tgagttcttt
    13561 atggtagtga ttgaccagtt ttcctttggc tgaaatccaa gtgttgtttt catactgccg
    13621 ggtattgccc ttggtcagca atccatagac accagaatct gcgatacagt ggataatgcc
    13681 gaagcggaac agaaattggc tattgtcatg actggggtcg ttatagacaa agcctgtaaa
    13741 ctggattgtc ttgccctcaa actcatctgg atagtcgtag atagcctcca tgacttccat
    13801 atagttttca ttagtgatct gaatactatc ttgggataag tatttatccg ccgccgttcg
    13861 catttccttt tcataggctg attttgaaaa ataagaactg gtatctggtt tcaaatattg
    13921 gcttgtcgtc ccttcgcttg tctgaatggc tagatccgtt ccttctgata gggggaaatg
    13981 ataaccttta gcagaaacgg tctgagaatc caagctaaca gttgggaaag ttaagccgat
    14041 gacaagtgga atagccagaa gagaaatact cgtcatcttg gccaatcggc tgttcagatg
    14101 actgtgggtt ttgactcgct tcatccagat atacaattga acgatagcca agataaaaga
    14161 aagtaccatg gaaatatagg ctagatagga atagtgcatg ttgatgtact ggtttagttt
    14221 gcccgacaga tggaggtaaa tagtcagttc aaaatagcca gctaaaacta aaaatcgaat
    14281 cataggatga ctccaatcaa gagagaatag actaagacga caagagttac aatcgttatg
    14341 aagtgactga taaatcgtgc tttcaagtaa tttttcatca tgagaatatt tttgatatcc
    14401 agcattggac caatgacgag aaaggccaga actggtgcca aaccgaaact cgagagaaga
    14461 gaagcaccta taaaggcatc cgcctcacta cagagcgaaa gaagaaaggc caaaatcatc
    14521 aagagcagga tggcaaaaag aggggttgca ctgatagagg tcagaatccg agtcggaacg
    14581 tagacctgta ttatagaagc aaagaggcaa ccaaatacca aataacgccc cgtatcaaaa
    14641 aattcatcaa tggcctgcac aaagacttga aaaacttttt ttgcagaact caagtaagaa
    14701 aaatcatgct catgacaagc cagacgattt tctttctgaa tcggttcttg ccagaaaaat
    14761 cctagaaaaa ttcctagtat tacagccaca agaatggaac ccagagctcg taatagggcg
    14821 acatggaagg agttgccaaa ggcagaatag gtcgcaaaaa gaacaatggg attgataaca
    14881 ggtgctgtca caagaaaagg aacggccgtg taacttggaa cctttttttc cagaaaacga
    14941 ttgataatgg ggacgattcc acattcacaa gaagggaaaa gcataccgac gaaggtccca
    15001 aaaaagattc ttccccaacg atttcgaggg agaaaatgat aaaccttttc aggtgtgata
    15061 taaacctcaa tcagccctga gacaatgctt cctatcagaa cgaagggaag ggcttcaatg
    15121 ataatggaga gaaaaatggc tccagtttga agtacactag atgggagttg ttgaaaagca
    15181 gtcatctagt ttttcttttc tgctttggct tttttctctt tgtcatcagg gaaagtaact
    15241 tgtttcaaat cagggagttt agcaaactct tcaaacatct tgtccaagtc gtctcgtttt
    15301 gtaaatttta cagccatagg tgtacctcga ttctaaatcc tacctctatt atactattat
    15361 tttgcggaaa aggaagtttt ttaatttgtt ttcgatagtt gatactcttc gaaaatctct
    15421 tcaaaccacg tcagcttcgc ctttccgtag tacggttact gacttcgtca gttctatcca
    15481 caacctcaaa acagtgtttt gagctgactt cgtcagtctt atctacaacc tcaaaacagt
    15541 attttgagct gacttcgtca gtcttatcta caacctcaaa acagtatttt gagctgactt
    15601 cgtcagtctt atctacaacc tcaaaacagt attttgagca gcctgcggct agcttcctag
    15661 tttgcttttt gatttttatt gagtatgaaa aggattggag aaagccttcc agcttgtggt
    15721 ataatagatt catggataaa aaatatgaaa aaatctccca agatttggga gtgactttaa
    15781 agcaaattga taccgttcta agtttgacag ctgaaggggc gactattccc tttatcgcgc
    15841 gttatcgtaa ggacatgact ggtagtctgg atgaggtggc gattaaggcc attattgact
    15901 tggataaaag tctgacaaat ctaaatgacc gtaaggaagt tgttttagct aaaattcaag
    15961 aacaaggcaa gctgactaag gaattggaag aagctatctt agaagccgaa aaactagcag
    16021 acgtagaaga actctatctt ccatacaagg aaaaacgtcg aaccaaggcg aacattgccc
    16081 gtgaagctgg cctcttccca cttgctcgct tgattttgca gaatgtagct gacttagaac
    16141 aagaggctga gaagtttgtc tgtgaaggat ttgcgactgg taaggaagcc ttgtctggtg
    16201 cagttgatat tttggtcgaa gccttatcgg aagatgtgac cttgcgttcc atgacttatc
    16261 aggaagtgct gagacactct aaactcactt ctcaagtcaa ggatgaaagt cttgatgaaa
    16321 agcaggtttt tcagatttat tatgattttt ctgagacagt tgggaacatg cagggttatc
    16381 gtaccttggc tctcaatcgc ggggagaagc taggtgtctt gaaggtcgac tttgaacatg
    16441 cgacggaccg tattcttgcc ttctttgctg ctcgtttcaa ggtaaaaaat gcctatattg
    16501 atgaagtggt tcagcaatct gttaagaaga aggtcttgcc tgctatcgag cgtcgtattc
    16561 ggacagaatt gactgaaaaa gcagaagaag gagctatcca actcttttct gacaatctac
    16621 gcaatctcct cttggttgct ccactgaaag ggcgcgtggt tcttgggttt gacccagcct
    16681 ttcgtacagg tgccaagcta gctgtcgtgg atgcaacagg aaaaatgctg acaactcagg
    16741 ttatttatcc tgttaaacca gcatcagctc gtcaaatcga agaagccaag aaagatttag
    16801 cagatttaat tggtcaatac ggtgtagaga ttattgccat tggaaatgga acggccagta
    16861 gtgaaagtga agcttttgta gcggaagttc tgaaagattt ccctgaagtc agctatgtta
    16921 tcgttaatga aagtggtgct tctgtctatt ctgccagcga acttgctcgt caggagtttc
    16981 cagacttgac cgttgaaaaa cgctctgcca tttctatcgc ccgtcgtttg caagatcctc
    17041 ttgcggaatt ggtcaaaatc gatcctaagt caattggtgt cggtcaatac caacacgatg
    17101 tcagtcagaa gaaactatct gagagtctgg actttgttgt cgatacagtg gttaaccaag
    17161 ttggtgtcaa tgtcaataca gctagcccag ctcttctttc acacgtagct ggactcaata
    17221 aaaccatttc tgaaaatatc gtcaaatacc gtgaggaaga gggaaaaatc acttcacgct
    17281 cccaaatcaa gaaagttcct cgtttggggg ccaaggcttt tgaacaggct gctggtttcc
    17341 tccgtatccc tgaaagtagc aatatccttg ataatacagg agttcaccca gaaaattacg
    17401 ctgccgttaa ggaactcttc aaatgcttgg acattaagga tctgaatgaa gaggcccaaa
    17461 gcaaactcaa gtcgctttca gtcaaggaaa tggcgcaaga gttagacctt ggtccagaaa
    17521 ctcttaaaga tatcattgca gatcttctca aaccaggtcg agatttccgt gattcctttg
    17581 atgctccagt tctccgtcaa gatgtcctag atatcaagga cttagtggtt ggacaaaagc
    17641 tagaaggagt ggtgcgtaac gttgttgatt tcggtgcttt tgttgatatc ggaattcatg
    17701 aggacggtct catccatatt tcccatatga gtcgcaagtt tatcaaacac cctagtcaag
    17761 tggtggcagt tggagatttg gtgagcgttt gggttaagaa aattgatact gaacgtgaaa
    17821 aagttaatct gtctctccta gctccaaatg aaactgactg attacgtcaa gcaggtttca
    17881 ctagaagact tcggcagacc ttttatccat catgtccagt ggaataggcg tctacgttcg
    17941 acaggtgggc gatttttccc caaagatggg catttggatt ttaatcccaa ggtttatcag
    18001 gaactggggt tggacgtttt taggaaaatt gtccgacatg aactctgtca ttatcacctc
    18061 tattttcaag ggaaaggcta tcaacacaag gatcgggatt ttaaggaact gttgaaagca
    18121 gtggatggat tacggtttgt accatccttg cccaatagta actccaagcc aatcaagctc
    18181 tatcgttgcc aatcctgcca gcaaacttat cagcgtaagc gtaggattga taccaaacgc
    18241 tatcgctgtg gactttgtcg aggaaagttg ctattagtaa atcagcctga ggactgatga
    18301 aagccgagcc tatccgtgat atactatgtc taacctagca gaaagaggaa atatcatgaa
    18361 cagtaagttt tataaaatga gacgaaatcg catgatttca ggagttttag caggtctgtc
    18421 agacaagtgg aactttgatg ttacccttgt acgttttctg tttgccattt ttacagtcgc
    18481 aaactttgga cttggggtga ttatctatat catcctagct tctatcatgc caaccaagga
    18541 agaaatcgaa gcagaaatgt acggaacagg cccacgtaaa cgcaaagaag ctcaagccat
    18601 tgacgataat gaaggctggt tttggtgagg ttttacaaaa gatttggaat acgcaaaaag
    18661 ctttaaatca atagtctaaa ctgcttgatt taaagctttt ttacttttat actcaataaa
    18721 aatcaaagtg caaactagga agccagccgc aggctgtaat ttagtcggca atgtgaagtt
    18781 gatatagttt gcactttgat ttttgaatag tattaataat atttcgccag cttcatccac
    18841 aaactatagt ggattggaac tagaatagga cacctatact tctaaaaaat tgttagaaat
    18901 cgatttgact gtcctgatcg atttgtcctg ttcttatttc attttactat aaaagcagta
    18961 atttaaacgc agttttttaa tctatttttg ctgttgagac aatacatttt tggaaaaatg
    19021 gtggatgctg ataacaactg ataaccagca aataacataa gcagtgccgg taaattctgt
    19081 actgataaag tgtgtgtgtt caactaagag ctgaccgatg aatggagaga gcagatagag
    19141 aagtccgatg agtatatgtt ctttgtgttt cattaaagcg caccttcttt ccttataggt
    19201 tgaacgactt gcaagtgtta aattgaatgg tatgttatct aggtaagctt actaaaatgt
    19261 tagttcccgc ttcctccttt tcaaagtaag ctttttcaca cttatatttt acaactttaa
    19321 aaataggaaa tcaaatcatt ttctaagtaa ttttgcttat atttcaccca atcttacaaa
    19381 aatgtaagat taaagtctct tttgtaaggt taggttatgg caagcggtct ttttttgatg
    19441 taaactagac tcataaagaa caaaggagta acatcatgaa acaaatctta cataagaaaa
    19501 ctagaaaacc aagtcacaaa gaaattgagc gcgttcagct gggatgcact atgatgcaag
    19561 ctacatttca tttgatggga tattaagaaa ggagattctc atgacacttt tagatgtaaa
    19621 acacgttcaa aaaatttata aaacacgttt tcagggcaac caagtagagg ccctcaagga
    19681 tattcacttt accgtagaaa agggtgacta cgttgccatc atgggtgagt ctggttctgg
    19741 taaatcaact cttctcaata ttctagctat gttggataaa ccaactcgtg ggcaggttta
    19801 cttgaatgga actgacaccg caactattaa aaattcacag gcttctagtt tccggcgtga
    19861 aaagctagga tttgtcttcc aagactttaa cttgctagat actctgtctg ttaaggacaa
    19921 tatcttgctt ccgcttgtct tgtcaagaag acctataacg gagatgatga agaaattggt
    19981 ggtgacagct gagaatctgg gtattaacca attgcaagag aagtaccctt acgagatttc
    20041 tggtggtcag aaacagcgtg tagcagtagc ccgcgccatc atcacagaac ctgaaattct
    20101 ccttgcggac gagccaacag gagcccttga ttccaagtca tctgcagcct tacttgatgt
    20161 ctttaatgaa atcaatgagc gtgggcaaac catcctcatg gtaacccact caacagcagc
    20221 tgctagcagg gccaagcgtg ttctctttat caaggacggc attctttaca accaaatcta
    20281 ccgtggagag aagacagagc gtcagatgtt ccaagaaatc tctgatacct tgactgtcat
    20341 ggcaagcgag gtgaattagt atgtttcgat taaccaataa gttagcggta tcgaacttga
    20401 ttaaaaaccg caaactctac tatccctttg cactggctgt tctcttggca gtcaccatca
    20461 cctatctctt ttactcccta accttcaatc caaagattgc ggaaatccgt ggaggaacca
    20521 ccattcaagc aacacttgga tttggtatgt ttgtcgttac ccttgcgtca gccattatcg
    20581 tcctctatgc caatagtttt gtcatgaaaa accgttccaa ggaactgggt atatatggca
    20641 tgttaggctt ggagaagcgc catctaatca gtatgacctt taaggagtta gtgctatttg
    20701 ggattctaac tgttggagca ggaatcggta ttggagcctt gtttgacaag ttgattttcg
    20761 ctttcctact caaactgatg aaattgaagg tggaactggt cgctaccttc cagatgaaag
    20821 ttgtcattac agtacttctt gtcttcggtt tgattttcct aggcctcatg ttcctgaatg
    20881 cccttcgaat cgcccgtatg aatgccctcc agctctcacg tgagaaagct agcggagaga
    20941 aaaaaggtcg cttccttcct ctccaaacga ttcttggttc cataagttta gggattggct
    21001 attatcttgc ccttacggta accgatcctc ttacagccct aacaactttc ttcctagctg
    21061 ttttgctggt tatctttggt acttatctat tgtttaatgc agggattaca gtcttcctac
    21121 aaatcttaaa gaaaaacaag aaatactatt accaacctaa taacctcata tctgtttcca
    21181 acttgatttt ccgtatgaag aaaaatgcgg ttggactagc aaccatcgct attttgtcaa
    21241 caatggtttt ggtaaccatg tcagcagcga caagcatttt caattccgca gaaagcttta
    21301 aaaaagttct aaatcctcat gattttgggg tttcagggca aaatgttgaa aaagaagatt
    21361 tggacaaact cttgagccag tttgcaagtg acaaaggtta tagtgtcaaa gagaaagaag
    21421 tacttcgtta cagtaacttt ggtattgcaa atcaagaagg aaccaagtta actatttttg
    21481 aaaaaggaca aaaccgtgtc caacccaaaa cagttttcat ggtatttgac caaaaagatt
    21541 atgaaaatat gactggtcaa aaactgtctc tatcaggaaa tgaggtcgga ctctttgcaa
    21601 agaatgaggg agttaaagaa cagaaagctc taactctaaa tgatcatcaa ttttctgtaa
    21661 aagaagaatt tactaaagat ttcattgtaa accatgttcc aaatcagttt aatattttga
    21721 cttctgatta caattacctt gttgtaccta atttacaagc ctttttggac caattcccag
    21781 attcggctat ctataatcag ttttacggcg gtatgaatgt aagtatcagt gaagaagagc
    21841 aactcaaagt cgctgaagaa tatgaaaaat acctcgatca atttaatgct caattaaaca
    21901 cggaaggtag ctatgtttat ggtagcactc tagcagatgc tagtgctcag atgagtgccc
    21961 tctttggtgg tgtcttcttt atcggtattt tcctatccat tatctttatg gtcggaaccg
    22021 ttctggtcat ttactacaaa caaatttctg aaggctatga agaccgtgag cgctttatta
    22081 tcttgcagaa agttggttta gatcaaaagc aaatcaagca aaccatcaac aaacagattt
    22141 taacagtttt cttccttcct ttgctctttg ccttcataca tttagccttt gcctaccata
    22201 tgcttagtct gattttaaaa gtgattggtg taatagatac gactatgatg ttgattgtga
    22261 ccttgtctat ctgcgctatc ttcctcatcg tctatgtgct gattttcatg attacttcaa
    22321 gaagctatcg caagattgta caaatgtaaa aaaagatacc tcgacttcaa aatcgaggta
    22381 tttcttgtat tttatactca atgaaaatca aaaagtaaac taggaagcta gccgcaggtt
    22441 gctcaaagca ctgctttgag gttgcagata gaactgacga agtcagctca aagcactgct
    22501 ttgaggttgc agatagaact gacgaagtca gctcaaaaca ctgttttgag gttgcagata
    22561 aaactgacga agtcagctca aaacactgtt ttgaggttgc agataaaact gacgaagtca
    22621 gtaaccatat atacggcaag gcgaagctga cgtggtttga atttgatttt cgaagagtat
    22681 taaatgctga aaagttgtcc tagcaaaaag gtaactccca tggtcaagag accaatagct
    22741 aggttccgaa tcatagctgt tttggttgga tcctttccaa gtctggcact agtgtaacca
    22801 gtgagaagaa gggccacacc gacgataagg acagtagcag ggatgcggta ttcacttggg
    22861 aaaatggtaa ttgaaagcat tggtggtaag ctaccaagga aaaaggcaac gaagctagaa
    22921 atagcagcgt gccaaggatt agtaaattct tcatactcaa tcccatattt ttcttctacc
    22981 agagccttga gtggattttt aagaaaggcc ttgttggtca agagttgggc agaggtttcg
    23041 cattctccat tttggatata ggctgcatag agagattttt tggctagttc catatcttgg
    23101 tctagcaaga gtttttctcg cgaaacggca gcttcctcgg tatcttttgg agttgaaacg
    23161 gatacatatt ctccacctgc cattgaaaag gcaccagcta agatagccgc aaaacctgac
    23221 aaaaagataa tccagatatt gcttgtagca ctggcaaccc caataaccac accagcaatg
    23281 gaaataatcc catcattagc accaagaaca cccgcacgca ggatatttaa acgacctgca
    23341 aaatttgaat cgatttcgtg atttgtttct gacatactaa tctccttttt atccagtata
    23401 aaggaaaaat atagggaaat caatctttta aaagtatctg aaaaaagttg cacgatttta
    23461 atgatataaa aatgtcgaca tcttttctga tagatcaaac accgaaggta aagagtatag
    23521 aatagcataa aaattttaaa ttaaatacga taaacatttt gttcacttta taatcgttta
    23581 caataaaata agtagtatta aatcaaataa aatccaaata ttttgcgaac ttttttatat
    23641 ttttttcgta aaccgcttta caagttctta aaaacatgat atagtaataa agcttagaaa
    23701 atgagatgat gttttctagc aaatataaac ccgagtaaaa aatgcctacg gacaggcagg
    23761 gttgaatgcc gaagcgtggt tgaaaagcca cattattgat agggttaaaa gcctactttt
    23821 ataagttgat gttaggacac ttgtcctaat tcataaattt ttagtgtggt gaaagcacac
    23881 gtcatcttgt gaaacgatca ataaagtacg taatatttgc tactagagag ttaggaaaca
    23941 tcgggaacag acatactcaa cagaaaccaa aataaacacg tcagaagatt gcagagcagg
    24001 tgaaaacctg ctcttttttc atgagtcaac ctttagttcc ttagttttca taaggtccta
    24061 aaaatattga aaggagtatg tcttgaagga gttagatcaa aaccaagccc caatttatga
    24121 ggccttggtg aagttacgca agaaaaggat tgttcccttt gatgttccag gtcacaagcg
    24181 tggacgagga aatccagaac ttgtcgaact cttaggagaa aaatgtgtag gcattgatgt
    24241 caattcgatg aaacccttgg ataatttagg ccatcctatt tcgattattc gtgatgcaga
    24301 ggagctggct gcagatgctt ttggagctag ccatgctttt ctaatgatag ggggaacaac
    24361 ctcatcggtg cagactatga ttctgtcaac ctgtaaggca ggagataaga ttattctgcc
    24421 acgaaatgtc cataaatctg ctatcaatgc gctggttcta tgtggtgcca ttcccatcta
    24481 tatcgagatg agtgtggatc ctaagattgg tatcgcttta ggtcttgaaa atgttcgagt
    24541 agcacaggcc ataaaagacc atccagatgc caaggccatt ttgattaaca atcctactta
    24601 ctacggaatc tgttcagacc taaaggggtt gacagaaatg gctcatgaag ctggtatgat
    24661 ggttttagta gatgaagccc acggagcgca tttgcatttt acagataaac ttccaatttc
    24721 tgctatggat gcaggtgctg atatagcagc agtctccatg cataagtctg gtgggagttt
    24781 gacacaaagt tcgcttcttt taatcggaga gcagatgaat cccgagtacg ttcgtcagat
    24841 catcaacctg acccaatcaa catctgcttc ttacctgttg atggctagtt tggatatttc
    24901 acgtcgcaac ttggcccttc gtggtaaaga gtcgtttgag aaggtcattg agctatccga
    24961 gtacgctcgt cgtgaaatca atgctattgg tggatactat gcctactcaa aagagttaat
    25021 agatggtgtg tcggtctgtg attttgatgt aaccaagctg tcagtttaca ctcagggtat
    25081 tggcttaaca ggtatcgagg tttatgactt cctacgagac gaatacgaca ttcagattga
    25141 gtttggtgat attggcaata tcttggccta tatttcgatt ggtgaccgca tccaagacat
    25201 cgagcgcttg gtcggtgctt tggctgacat aaagagactc tattcacgag atgggaagga
    25261 cttgatagca ggagaatata ttcagcccga gttggtgtta tctcctcagg aagccttcta
    25321 ttcagagaga aaaagtttaa ccttggacga atctgttgga caagtctgtg gagaatttgt
    25381 catgtgctat cctccaggga ttcctatctt ggctcctggt gaacgcatta cacgagaaat
    25441 tgtagactat atccaatttg ccaaggaacg tggttgttcc ctccaaggga cggaagatcc
    25501 tgaggtcaat cacatcaacg tcattaagag aaaggagaac tagatggatt tatggttttc
    25561 tgaagttcat actccagatg taaaattgtc cctgagaaca gccaagcaac tctacgctgg
    25621 aaaaagtgaa tggcaagata tcgaagtctt ggatacacca gcttttggga aaatactgat
    25681 tttaaatggg cacgtcttat tttcagatgc ggatgacttt gtctacaatg aaatgaccgt
    25741 tcatgttccc atgactgtcc acccaaatcc caagaaagtc ttggttattg ggggtggtga
    25801 cggtggtgtt gctcaagtat taacacttta tccagaattg gaacaaatcg atattgtaga
    25861 acctgatgaa atgttggttg aggtttgtcg tgagtatttt ccagactttg ctgcagggct
    25921 agatgatcca cgtgttacca tttattatca aaatgggcta cgttttttgc gaaactgcga
    25981 agatgattat gatattatca tcaacgatgc gacagatccc tttggctata cggaagggct
    26041 ctttactaag gaattctacg gtaatagtta tcgagctctg aaggaagacg gcattatgat
    26101 ttaccagcat gggagtccct tctttgatga ggatgagtcg gcttgccgaa gcatgcaccg
    26161 aaaggtcaat cagacctttc caattagtcg tgtctaccaa gcccatatcc ctaccagtcc
    26221 ggcgggctat tggttatttg gatttgcatc gaaaaaatac catcctgtca aagattttga
    26281 caaggaaggc tggaaaaaac gccagctttt cacaaaatac tacactgcaa acttacatgt
    26341 aggagccttt atgttgccca agtatgtaga agacatttta gaagaagagg aaggaaaaaa
    26401 atgagtcgtt tactagttat tggttgtggg ggcgttgccc aagttgctat ttcgaagatt
    26461 tgtcaagata gcgaaacatt tacagagatt atgattgcta gccgtaccaa gtcaaaatgt
    26521 gatgacttga aagctaaact ggaaggcaaa acaagtacaa agattgagac agctgctctt
    26581 gatgctgaca aggttgaaga agtgattgcc ctgattgaaa gctacaaacc agaagctgtt
    26641 ttgaatgtag ctctgcctta tcaagattta accattatgg atgcttgttt ggcaacaggt
    26701 gttcactata tcgatacagc caactacgaa gcagaagaca cagaagaccc tgagtggcgt
    26761 gctatctacg aaaaacgttg taaggaactt ggttttacag cctactttga ctactcatgg
    26821 cagtgggctt atcaagagaa attcaaagaa gcaggcttga ctgctcttct tggttctggt
    26881 tttgacccag gtgtaactag tgtcttttca gcttatgccc tcaaacacta ttttgatgaa
    26941 atccattata tcgacatttt agactgtaat ggcggtgacc acggttatcc atttgcaacc
    27001 aacttcaacc cagaaattaa tctccgtgag gtttctgcgc caggttctta ttgggaagat
    27061 ggacaatggg tcgaagtcga agctatgtct atcaaacgtg agtacgattt ccctcaagtt
    27121 ggacaaaaag atatgtatct ccttcaccat gaagaaattg aatcgctggc caagaacatt
    27181 cctggagtca aacgcattcg tttctttatg acttttggtc aatcttactt gacacatatg
    27241 aaatgtcttg aaaatgtagg actccttcgt acggatacca ttaacttcaa tggacaagac
    27301 atcgttccga ttcaattctt aaaagccttg cttccagccc ctgccagtct tgggccacgt
    27361 acagtcggaa aaaccaatat tggatgtatc tttacaggtg tcaaagatgg cgttgaaaag
    27421 actatctaca tctacaatgt ttgcgaccat caagagtgct atgcagaagt cgggtcacaa
    27481 gcaatttcat acacgacagg agttccagcc atgattggga caaaattagt catgaacgga
    27541 acttggaaac aagctggagt gtataacctt gaggagttag atccagatcc attcatggaa
    27601 gctttgaatg agtatggttt gccatgggtt gtggttgaaa atccacaaat ggtggactaa
    27661 tgaagttaga acaagtacca acaccagcct atgttattga cttggccaag ttagaagcta
    27721 attgccgcat tctacaatat gtacaagaag aggccggttg caaggtcttg cttgcccaga
    27781 aggcatattc cctctacaaa acttatccct tgattagcca gtatctatca ggtacgacag
    27841 ctagtggact ctatgaggcc aaattggcaa gggaagaatt tcctggtgaa gtccatgtat
    27901 ttgcgcctgc tttcaaggat gcagacttgg aggaattgct agagataacg gaccatatcg
    27961 tctttaactc agagagacag ttgcgtaaac acggtccgcg ttgtcgagag gctggtgtca
    28021 gtgttggttt gcgcctcaac cctcagtgtt caactcaagg agatcacgcg ctctatgacc
    28081 cttgtgcacc aggttctcgc tttggagtta ctatagacaa gattccgagt gatttgctgg
    28141 atttggttga cggacttcat tttcataccc tttgcgagca gggagcagat gatttacaaa
    28201 caactttgaa agcagtagaa gaacagtttg gtccctactt acatgaggta aaatggctca
    28261 atatgggtgg tggtcatcat attacaagag aaggttacga tgtggatttg ctgatttcag
    28321 aaatcaagcg tatccgaaaa acttacaatc ttgaaatcta tatcgagcct ggtgaagcca
    28381 ttgcgcttaa tgcgggttat ttagcaactg aggtattaga tattgtagaa aacggtatgg
    28441 aaatcttggt tttagacgcc tctgcgacct gccatatgcc tgatgtactt gagatgccct
    28501 atcgtccacc tttgagaaat ggctttgagg cacaggaaaa agcccatacc tacagacttt
    28561 cttctaatac ctgtctgacg ggcgatgtga ttggtgatta tagttttgaa aatccagtcc
    28621 aaatcggaga cagactttat tttcaagaca tggccattta ttcttttgtc aaaaataata
    28681 cctttaatgg tattggattg ccaagtctct atctcatgga cgaacaggga gactgtagct
    28741 tactcaaagc ttttggctat caagacttta aagggagatt atcatgatgg acagtccaaa
    28801 aaaattaggc tatcacatgc cagcagagta cgaaccccat catggtaccc tcatgatatg
    28861 gccgactcga ccaggatcat ggccttttca aggaaaggct gctaaaagag catttactca
    28921 gatcatcgag accatagcag aaggggaaag agtctatctt ttggtggagc aggcctatct
    28981 atctgaagcc caatcctatc ttggagacaa ggttgtttat ttagacattc ccaccaatga
    29041 tgcctgggcg cgtgatactg gcccaaccat tctcgtcact gataaaggta agaaattagc
    29101 cgtggattgg gcctttaatg cttggggagg cacctatgat ggtctttatc aagattatga
    29161 agaggatgac caagtagcca gtcgttttgc tgaggccttg gaaaggcctg tctatgatgc
    29221 taaacctttt gtactggaag gaggcgcaat ccatagcgat ggtcaaggaa ctattctcgt
    29281 aactgaaagt tgcttgctta gtcctggtcg caatcctaac ctgactaaag aggagattga
    29341 aaacacatta ttagaaagtc ttggtgctga aaaagttatt tggcttcctt atggtattta
    29401 tcaggatgaa accaatgaac acgtcgataa tgttgctgcc tttgttggtc ctgctgagct
    29461 tgttttggct tggacagatg acgaaaatga tccccagtat gccatgtcaa aagcagatct
    29521 cgaactctta gaacaggaaa cagatgcaaa aggttgtcac ttcaccattc ataaattgcc
    29581 tatccctgca gttcgacaag ttgtgacaga agaagatttg ccaggctaca tctatgaaga
    29641 aggagaagaa aagcgatacg caggtgaacg actagcagct tcctacgtaa acttttatat
    29701 cgccaacaag gctgtcttgg ttccacagtt tgaggatgta aacgaccaag tggccttaga
    29761 tatcctcagc aagtgtttcc cagaccgtaa agttgtcgga ataccagcca gagatattct
    29821 cttaggtggt ggcaatatcc actgtatcac ccaacaaatt ccagaatagg agaaaaagat
    29881 gagaaatgta agagttgcaa ccattcagat gcaatgcgct aaggatgtgg caacaaatat
    29941 ccaaaccgca gagcgtttag tacgtcaggc tgctgagcaa ggagcccaaa ttattctctt
    30001 gcccgagttg tttgaacatc cctatttctg tcaggaacgt cagtatgact actaccagta
    30061 tgcccaatct gtagcggaaa atactgccat tcagcatttt aaggtgattg ctaaggaact
    30121 acaagttgtt ttaccaatca gtttctatga aaaagatggt aatgtcttgt ataactctat
    30181 tgccgtcatt gatgcagatg gggaagtgct gggcgtttat cgaaagaccc atataccaga
    30241 tgaccattat tatcaagaaa aattctattt cacgcctggt aacactggtt tcaaggtctg
    30301 gaatactcgc tatgctaaga ttggtatcgg tatctgttgg gatcaatggt tccctgaaac
    30361 agcgcgctgt cttgcattga atggtgctga attgctcttt tatcctacag ctatcggttc
    30421 agagccaatt ttggatacag atagttgtgg tcactggcaa cgtactatgc aagggcacgc
    30481 agcagcgaat attgttccag tcatcgcagc caatcgttat ggtttagagg aggttactcc
    30541 tagtgaggaa aatggcggac agagttccag tcttgacttc tacggttcct cctttatgac
    30601 ggatgaaaca ggagctattc tagaacgagc tgaaagacaa gaagaagctg ttctgttagc
    30661 tacttatgac ctagacaagg gagcaagtga acgcctaaac tggggcttgt ttcgagatag
    30721 aagaccagaa atgtatagac aaattacaga ttagtgtggg agaaatgaga gattcattct
    30781 gctagactaa cttcttatta gcaactataa gatactatgg catctagtaa atcgattttt
    30841 atgattcgct attcttgtct attgattagt ccgtatttta aaatattagc aaaaaagcaa
    30901 atagcagtaa cttctgtcta tttgcttttc ttttttatag aatatatttc tcaatagcac
    30961 gcgcaacgcc gtcttcttcg ttgcttgatg taacggcatc cgcaagagat ttgacataat
    31021 cgctggcatt tcccattgca atcccaagcc ctgcaaactg gagcatttcg atatcgttat
    31081 tagcatcgcc catggccata atctctgagg aatcaatctt caaaatctca gctagtcgtg
    31141 aaagagcagt agcctttgtc gttccaagcg gcattgcttc ataaatgaca ggctgcgaac
    31201 gaactccact gaatcgttgg caaagctctt cagcaaaacg ctgctcaaaa tcgtctgttt
    31261 gttcttttgt tcctaaaaac ataccttgga acatccggaa ctttccacta gtcgcttctt
    31321 caagagaaat ttcagtcagg tctgaaaata ctagtttagc atcattttca ataacttgat
    31381 tgggtttgcc accgagaaca aaataatgtg actcgtcaaa aagtgtcaac tgaacatcac
    31441 tcttttcagc aaggtcatag aggtattcga tgtcagctgg actcagttct tgccagtcaa
    31501 ccaagcccca gtcgctagtc tggtgagttg aacaaccgtt gttaacaata atatattcgt
    31561 tctggaggtc aagctccagt tttttgtagt aggggaggac accgaaaagg gggcgacccg
    31621 tacagagaac cagtttgaca cctttttcaa tggctttgtg aatagcagta atgtgagctt
    31681 gtgggatttc cttggcttca ttgaggaggg tgccgtccat atccaaggct agtagtttaa
    31741 tcataggtct tccttcttta tcttttgcta ttattatagc atattttgga gaagaaattg
    31801 atagaaagct tgagactaat tgattttata gtttaagatg ttttgatgac aattcatgat
    31861 ttgaagagga tatttcgcaa agatatgcta tgctatgttt gtcaatgttg caactagaca
    31921 aattaaaaaa ccaacttaat ataatagttt ttttgtaagt aggtatgagt atcagattac
    31981 tcaactaatc tgaagaataa tggaggaaat atatcatgat tttaatgaca aaaaatataa
    32041 atctaacaaa tgaagaatta gagctgatac aaggtggagc agatccctat ggtaaaaatc
    32101 ctaatggtag gtacgattgg gaaatagaac cagtattaac tctgccggtt catggatttt
    32161 gtcccagagg cacctatgat ttaggatata ttggaggagg caatcatctt tgcaaaggaa
    32221 gtgctgcgag attttaagta aaatttatta ggaatatgaa gaaacaaggg gagaaaacag
    32281 aggatttaat atgaaaaaac gagctattca aattttacta gtattgtcct taatttttta
    32341 caaatcaact tggttttgga ggcttttcaa ttatctcgca aagccctatc taccagcaag
    32401 tcgtgaattt tttcagattc tgcttttgat ggagagtgga gttcttttat tagcggtcat
    32461 ctatctacta gtttttgcag gaaagaaaac ttttcatttc aagtggcagc tgaggtattt
    32521 tatctacctt ttactgggtt acatcacttc gtatatgtct gactttctct tttcgtattt
    32581 catatctctg tcttcaaatc aaatttcttt gaatgaaacg atagaaatga tagggagaca
    32641 ggaattaccc tattttttgc tcatcgtttg cttcatcggc cctattgctg aggaattgat
    32701 ttatcgcggt gtgcttatga caaccttttt caaaaactcg ccttggtacg gagatgtctt
    32761 gctttctgct attattttcg gttatattca tatcaatttt gctttaactc ctcttgcttt
    32821 tttcatttat gctagtggag gtcttatttt agctctattg tatcgcatga ctaaaaatct
    32881 ctactatcca atactagttc atattctcat taatatcact gccttctggg atgtgtggtt
    32941 gctcctattt tcaggaagtt agcttactaa aataatgtcg gaactttccg gcattttctt
    33001 ttttcacaaa tagtcaacgt ttttcttttc gatattgtag tggtgtgtat ccagttattt
    33061 ttttgaattg attttgaaaa taaggttggc ttgagaaagg cagatagtga agatagttaa
    33121 gaagaatagg atgttctttt ttcctttttg gaaaacttct aaaatatggt ataatgaaaa
    33181 gataaagaag ttaggggtag aagatgaaca ttcaacaatt acgctatgtt gtggccattg
    33241 ccaatagtgg tactttccgt gaagctgctg aaaagatgta tgttagtcag ccgagtctgt
    33301 ctatttctgt tcgtgatttg gaaaaagagt tgggttttaa gattttccgt cggaccagct
    33361 cagggacttt cttgacccgt cgtgggatgg aattttatga aaaagcgcaa gaattggtta
    33421 aaggatttga tatttttcaa aatcagtatg ccaatcctga agaagaaaaa gatgaatttt
    33481 ccgttgctag ccagcactat gacttcttgc caccaactat tacggccttt tcagagcgct
    33541 atcctgacta taagaacttc cgtatttttg aatcaactac tgttcaaata ttagatgaag
    33601 tggcgcaagg gcatagtgag attgggatta tctacctcaa caatcaaaat aaaaagggga
    33661 ttatgcaacg ggttgaaaaa ttaggtctgg aggtcatcga attgattcct ttccataccc
    33721 atatttatct ccgtgagggt catcctttag cccagaaaga ggaattagtc atggaggatt
    33781 tagcggattt accaacggtt cgtttcactc aagagaaaga cgagtacctt tattattcag
    33841 agaactttgt cgataccagt gcaagctcac agatgtttaa tgtgacagac cgtgccactt
    33901 tgaatggtat tttggaacgg acggacgcct atgcgacagg ttctggattt ttagatagtg
    33961 acagtgttaa tggcattaca gttattcgtc tcaaggataa cctagataac cgcatggtct
    34021 atgttaaacg cgaagaagtg gagcttagtc aagctgggac tctcttcgta gaagtcatgc
    34081 aagaatattt tgatcaaaag aggaaatcat gaaaaaaaga gcaatagtgg cagtcattgt
    34141 actgcttttg attgggctgg atcagttggt caaatcctat atcgtccagc agattccact
    34201 gggtgaagtg cgctcctgga ttcccaattt cgttagcttg acctacctgc aaaatcgagg
    34261 tgcagccttt tctatcttac aagatcagca gttgttattc gctgtcatta ctctggttgt
    34321 cgtgataggt gccatttggt atttacataa acacatggag gactcattct ggatggtctt
    34381 gggtttgact ctgataatcg cgggtggtct tggaaacttt attgataggg tcagtcaggg
    34441 ctttgttgtg gatatgttcc accttgactt tatcaacttt gcaattttca atgtggcaga
    34501 tagctatctg acggttggag tgattatttt atcgattgca atgctaaaag aggaaataaa
    34561 tggaaattaa aattgaaact ggtggtctgc gtttggataa ggctttatca gatttgacag
    34621 aattatcacg cagtcttgcg aatgaacaaa ttaaatcagg ccaggtcttg gtcaatggtc
    34681 aagtcaagaa agctaaatac acagtccaag agggtgatgt cgtcacttac catgtgccag
    34741 aaccagaggt attagagtat gtggctgagg atattccgct agaaatagtc taccaagatg
    34801 aggatgtggt tgtcgttaac aaacctcagg ggatagttgt gcatccgagt gctggtcata
    34861 ccagtgggac cctagtaaat gccctcatgt atcatattaa ggacttgtcg ggtatcaatg
    34921 gggttctgcg tccaggaatt gttcaccgta ttgataagga tacgtcaggt cttctcatga
    34981 ttgctaaaaa cgatgatgcg catctagcac ttgcccaaga actcaaggat aaaaagtctc
    35041 tccgcaaata ttgggcgatt gttcatggaa atctgcctaa tgatcgtggt gtaattgaag
    35101 cgccgattgg ccggagtgaa aaagaccgta agaaacaggc tgtaactgct aaagggaaac
    35161 ctgcagtgac gcgttttcac gtcttggaac gctttggcga ttataactta gtggaattgc
    35221 aactggagac agggcgcact catcagattc gtgtccacat ggcttacatc ggtcatccag
    35281 tcgctgggga tgaagtctat ggttctcgaa agactctgaa aggacatgga caatttcttc
    35341 atgctaagac tttagggttt actcatccga gaacaggtaa gaccatggaa tttacagcag
    35401 atatcccaga gatttttaag gaaaccttgg agagattgag gaagtaagaa tgaaaaagaa
    35461 attaactagt ttagtacttg caggcgcttt tttaagttta tcatggtatg ggaatgttca
    35521 agctcaagaa agttcaggaa ataaaatcca ctttataaat gttcatgaag gtggtagtga
    35581 tgcgattatt cttgaaagca atggacattt tgccatggtg gatacaggag aagattatga
    35641 tttcccagat ggaagtgatt ctcgttatcc atggagacag ggtatcaata ccacttataa
    35701 gcatgttctg acagaccgtg tctttcgtcg tttgaaggaa ttgggtgtcc aaaaacttga
    35761 ttttattttg gtgacccata cccacagtga tcatattgga aatgttgatg aattactgtc
    35821 tacctatcca gttgaccgag tctatcttaa gaaatatagt gatagtcgta ttactaattc
    35881 tgaacgtcta tgggataatc tgtatggcta tgataaggtt ttacagactg ctgcagaaaa
    35941 aggtgtttca gttattcaaa atatcacaca aggggatgct cattttcagt ttggggacat
    36001 ggatattcag ctctataatt ataaaaatga aactgattca tcgggtgaat taaagaaaat
    36061 ttgggatgac aattccaatt ccttgattag cgtggtgaaa gtcaatggca agaaaattta
    36121 ccttgggggc gacttagata atgttcatgg agcagaagac aagtatggtt ctctcattgg
    36181 aaaagttgat ttgatgaagt ttaatcatca ccatgatacc aacaaatcaa ataccaagga
    36241 ttttattaaa aatttgagtc cgagtttgat tgttcaaact tcggatagtc taccttggaa
    36301 aaatggtgtt gatagtgagt atgttaattg gctcaaagaa cgaggaattg agagaattaa
    36361 cgcagccagc aaagactatg atgcgacagt ttttgatatt cgaaaagacg gttttgtcaa
    36421 tatttcaaca tcctacaagc cgattccaag ttttcaagct ggttggcata agagtgcata
    36481 tgggaactgg tggtatcaag cgcctgattc tacaggagag tatgttgtcg gttggaataa
    36541 aatcgaaggt gaatggtatt actttaacca aacgggtatc ttgttacaga atcaatggaa
    36601 aaaatggaac aatcattggt tctatttgac agactctggt gcttctgcta aaaattggaa
    36661 gaaaattgat ggaatctggt attattttaa caaagaaaac cagatggaaa ttggttggat
    36721 tcaagataaa gagcagtggt attatttgga tgttgatggc tctatgaaga caggttggct
    36781 tcaatataag gggcaatggt attactttgc tccatcaggg gaaatgaaaa cgggctgggt
    36841 aaaagataaa gaagcctggt actatatgga ttctactggt atcatgaaga caggtgagat
    36901 agaagttgct ggacatcatt actatctaga agaatcagga gctatgaagc aaggctggct
    36961 taaaaaggca aatgattggt atttctacaa gacagatggt tcacgagcta taggttggat
    37021 taaagacaag gataaatggt acttcttgaa agaaaatggt caattacttg tgaatggtaa
    37081 gacaccagaa ggctatactg tggattcaag tggtgcctgg ttagtggatg ttccgatcga
    37141 gaaatctgct acaattaaaa ctacaagtaa ttcagaaata aaagaatcca atcaagtagt
    37201 gaaaaaagat cttgaaaata aagaaacgaa tcaacatgaa agtgttgcaa gttcttcatc
    37261 tagtcaagat ttaacttcat caacttcaca aagctctgaa ataaatgcaa acaaatcgga
    37321 atcagaatag tagtaaaaga aggttttagg gccttctttt tcggctcttt gtcaactgta
    37381 gtgggttgaa gtcagctaag ctcgagaaag gacaaatttt gtcctttctt ttttgatatt
//
LOCUS       DAVDZK010000019        36865 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVDZK010000019 DAVDZK010000000
VERSION     DAVDZK010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36865
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.020"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(17..997)
                     /locus_tag="VUX16_001110"
     CDS             complement(17..997)
                     /locus_tag="VUX16_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET8124084.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELIKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            complement(1010..1756)
                     /locus_tag="VUX16_001111"
     CDS             complement(1010..1756)
                     /locus_tag="VUX16_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET8124085.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            1878..2654
                     /locus_tag="VUX16_001112"
     CDS             1878..2654
                     /locus_tag="VUX16_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET8124086.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            2729..2926
                     /locus_tag="VUX16_001113"
     CDS             2729..2926
                     /locus_tag="VUX16_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET8124087.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            3143..3739
                     /locus_tag="VUX16_001114"
                     /pseudo
     CDS             3143..3739
                     /locus_tag="VUX16_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            3815..4264
                     /locus_tag="VUX16_001115"
     CDS             3815..4264
                     /locus_tag="VUX16_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET8124088.1"
                     /translation="MCTILVSIYYKIGLSSSGVYKAVADVEMTVGLSYEDPAVKLLND
                     GANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQEVQDTLGTTTTNRPVR
                     KNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ"
     gene            4277..4914
                     /locus_tag="VUX16_001116"
                     /pseudo
     CDS             4277..4914
                     /locus_tag="VUX16_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            5050..5355
                     /locus_tag="VUX16_001117"
                     /pseudo
     CDS             5050..5355
                     /locus_tag="VUX16_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809465.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            5345..6990
                     /locus_tag="VUX16_001118"
                     /pseudo
     CDS             5345..6990
                     /locus_tag="VUX16_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(7093..7785)
                     /locus_tag="VUX16_001119"
     CDS             complement(7093..7785)
                     /locus_tag="VUX16_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET8124089.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEGGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(8029..9366)
                     /locus_tag="VUX16_001120"
     CDS             complement(8029..9366)
                     /locus_tag="VUX16_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET8124090.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSAVVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMRVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(9376..9642)
                     /locus_tag="VUX16_001121"
     CDS             complement(9376..9642)
                     /locus_tag="VUX16_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET8124091.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(9907..10293)
                     /gene="rplQ"
                     /locus_tag="VUX16_001122"
     CDS             complement(9907..10293)
                     /gene="rplQ"
                     /locus_tag="VUX16_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET8124092.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(10305..11240)
                     /locus_tag="VUX16_001123"
     CDS             complement(10305..11240)
                     /locus_tag="VUX16_001123"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET8124093.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(11283..11666)
                     /gene="rpsK"
                     /locus_tag="VUX16_001124"
     CDS             complement(11283..11666)
                     /gene="rpsK"
                     /locus_tag="VUX16_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET8124094.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(11684..12049)
                     /gene="rpsM"
                     /locus_tag="VUX16_001125"
     CDS             complement(11684..12049)
                     /gene="rpsM"
                     /locus_tag="VUX16_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET8124095.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(12067..12183)
                     /gene="rpmJ"
                     /locus_tag="VUX16_001126"
     CDS             complement(12067..12183)
                     /gene="rpmJ"
                     /locus_tag="VUX16_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET8124096.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(12208..12426)
                     /gene="infA"
                     /locus_tag="VUX16_001127"
     CDS             complement(12208..12426)
                     /gene="infA"
                     /locus_tag="VUX16_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET8124097.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(12543..13181)
                     /locus_tag="VUX16_001128"
     CDS             complement(12543..13181)
                     /locus_tag="VUX16_001128"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET8124098.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMVNQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(13332..14642)
                     /gene="secY"
                     /locus_tag="VUX16_001129"
     CDS             complement(13332..14642)
                     /gene="secY"
                     /locus_tag="VUX16_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET8124099.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDKTE"
     gene            complement(14655..15095)
                     /gene="rplO"
                     /locus_tag="VUX16_001130"
     CDS             complement(14655..15095)
                     /gene="rplO"
                     /locus_tag="VUX16_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET8124100.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(15240..15464)
                     /gene="rpmD"
                     /locus_tag="VUX16_001131"
     CDS             complement(15240..15464)
                     /gene="rpmD"
                     /locus_tag="VUX16_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET8124101.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(15436..15930)
                     /gene="rpsE"
                     /locus_tag="VUX16_001132"
     CDS             complement(15436..15930)
                     /gene="rpsE"
                     /locus_tag="VUX16_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET8124102.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(15948..16304)
                     /gene="rplR"
                     /locus_tag="VUX16_001133"
     CDS             complement(15948..16304)
                     /gene="rplR"
                     /locus_tag="VUX16_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET8124103.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(16388..16924)
                     /gene="rplF"
                     /locus_tag="VUX16_001134"
     CDS             complement(16388..16924)
                     /gene="rplF"
                     /locus_tag="VUX16_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET8124104.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VDGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(17116..17514)
                     /gene="rpsH"
                     /locus_tag="VUX16_001135"
     CDS             complement(17116..17514)
                     /gene="rpsH"
                     /locus_tag="VUX16_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET8124105.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(17728..17997)
                     /gene="rpsN"
                     /locus_tag="VUX16_001136"
     CDS             complement(17728..17997)
                     /gene="rpsN"
                     /locus_tag="VUX16_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET8124106.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(18015..18557)
                     /gene="rplE"
                     /locus_tag="VUX16_001137"
     CDS             complement(18015..18557)
                     /gene="rplE"
                     /locus_tag="VUX16_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET8124107.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(18581..18886)
                     /gene="rplX"
                     /locus_tag="VUX16_001138"
     CDS             complement(18581..18886)
                     /gene="rplX"
                     /locus_tag="VUX16_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET8124108.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(18964..19332)
                     /gene="rplN"
                     /locus_tag="VUX16_001139"
     CDS             complement(18964..19332)
                     /gene="rplN"
                     /locus_tag="VUX16_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET8124109.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(19358..19618)
                     /gene="rpsQ"
                     /locus_tag="VUX16_001140"
     CDS             complement(19358..19618)
                     /gene="rpsQ"
                     /locus_tag="VUX16_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET8124110.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(19643..19849)
                     /locus_tag="VUX16_001141"
     CDS             complement(19643..19849)
                     /locus_tag="VUX16_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET8124111.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTVRLKEVKKQIARIKTVQSEAK"
     gene            complement(19859..20272)
                     /gene="rplP"
                     /locus_tag="VUX16_001142"
     CDS             complement(19859..20272)
                     /gene="rplP"
                     /locus_tag="VUX16_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET8124112.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(20276..20929)
                     /gene="rpsC"
                     /locus_tag="VUX16_001143"
     CDS             complement(20276..20929)
                     /gene="rpsC"
                     /locus_tag="VUX16_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET8124113.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(20942..21286)
                     /gene="rplV"
                     /locus_tag="VUX16_001144"
     CDS             complement(20942..21286)
                     /gene="rplV"
                     /locus_tag="VUX16_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET8124114.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(21298..21579)
                     /gene="rpsS"
                     /locus_tag="VUX16_001145"
     CDS             complement(21298..21579)
                     /gene="rpsS"
                     /locus_tag="VUX16_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET8124115.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(21683..22516)
                     /gene="rplB"
                     /locus_tag="VUX16_001146"
     CDS             complement(21683..22516)
                     /gene="rplB"
                     /locus_tag="VUX16_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET8124116.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSCWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(22534..22830)
                     /locus_tag="VUX16_001147"
     CDS             complement(22534..22830)
                     /locus_tag="VUX16_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET8124117.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(22830..23453)
                     /gene="rplD"
                     /locus_tag="VUX16_001148"
     CDS             complement(22830..23453)
                     /gene="rplD"
                     /locus_tag="VUX16_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET8124118.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(23478..24104)
                     /gene="rplC"
                     /locus_tag="VUX16_001149"
     CDS             complement(23478..24104)
                     /gene="rplC"
                     /locus_tag="VUX16_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET8124119.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(24321..24629)
                     /gene="rpsJ"
                     /locus_tag="VUX16_001150"
     CDS             complement(24321..24629)
                     /gene="rpsJ"
                     /locus_tag="VUX16_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET8124120.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(24896..25513)
                     /locus_tag="VUX16_001151"
     CDS             complement(24896..25513)
                     /locus_tag="VUX16_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET8124121.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(25510..26100)
                     /gene="nrdG"
                     /locus_tag="VUX16_001152"
     CDS             complement(25510..26100)
                     /gene="nrdG"
                     /locus_tag="VUX16_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET8124122.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            complement(26093..26599)
                     /locus_tag="VUX16_001153"
     CDS             complement(26093..26599)
                     /locus_tag="VUX16_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124123.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            complement(26643..26783)
                     /locus_tag="VUX16_001154"
     CDS             complement(26643..26783)
                     /locus_tag="VUX16_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124124.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(26795..29002)
                     /gene="nrdD"
                     /locus_tag="VUX16_001155"
     CDS             complement(26795..29002)
                     /gene="nrdD"
                     /locus_tag="VUX16_001155"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET8124125.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLDDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKQEDYAWK
                     KAQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(29122..30660)
                     /locus_tag="VUX16_001156"
     CDS             complement(29122..30660)
                     /locus_tag="VUX16_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET8124126.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSFLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(30697..30840)
                     /locus_tag="VUX16_001157"
     CDS             complement(30697..30840)
                     /locus_tag="VUX16_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124127.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(30918..32450)
                     /gene="cls"
                     /locus_tag="VUX16_001158"
     CDS             complement(30918..32450)
                     /gene="cls"
                     /locus_tag="VUX16_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET8124128.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(32596..33141)
                     /locus_tag="VUX16_001159"
     CDS             complement(32596..33141)
                     /locus_tag="VUX16_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET8124129.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKSIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDID
                     GTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVN
                     GNQIVVDDMDRDPSDQIVLTK"
     gene            complement(33138..34388)
                     /locus_tag="VUX16_001160"
     CDS             complement(33138..34388)
                     /locus_tag="VUX16_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET8124130.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(34695..35000)
                     /locus_tag="VUX16_001161"
     CDS             complement(34695..35000)
                     /locus_tag="VUX16_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET8124131.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(35016..35435)
                     /gene="ruvX"
                     /locus_tag="VUX16_001162"
     CDS             complement(35016..35435)
                     /gene="ruvX"
                     /locus_tag="VUX16_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET8124132.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(35439..35705)
                     /locus_tag="VUX16_001163"
     CDS             complement(35439..35705)
                     /locus_tag="VUX16_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET8124133.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(35792..36361)
                     /locus_tag="VUX16_001164"
     CDS             complement(35792..36361)
                     /locus_tag="VUX16_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET8124134.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGSATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSNYISDRLANGATEQ"
     gene            complement(36427..36825)
                     /gene="spx"
                     /locus_tag="VUX16_001165"
     CDS             complement(36427..36825)
                     /gene="spx"
                     /locus_tag="VUX16_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET8124135.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
BASE COUNT        10631 a         8074 c         6583 g        11577 t
ORIGIN      
        1 aatcagtcta tcattttcac tcacctagaa tctctctaaa agtcaaatcc ccatcttctt
       61 ccaaaacttt taaaattgta tttttgtctg taatcaaatg atttactaaa ttagcacgca
      121 agacagaaag aatcgaagat actttcgtat caccgtaagc aacagctaaa ctttgaggaa
      181 tattttttaa atcttccaaa gagattgcta tcgttctttc ctgtaagttt tcatagactt
      241 ctttaccttt tgaatcaaaa aatcgacaac aaatttctcc tacagtttta actttgatca
      301 attctttaaa gtcatcctct gtaagcatgt ctaaccattg atgttttcct ttattgctaa
      361 aatcaccaat tccgactaca gctatatcta aatctttcca actatttttc aaattttcaa
      421 aatatcttga ttgcaaaata ccatctgcta acaatttatt ttcttgcaca atcgttgcat
      481 tcataaatgt acactctcca tgaaattttc tagacatttc ataaatcagt gtattcacat
      541 ggtatttagc gtgtatgtga ctaggaccac ctgctagagg atagaagtga acatttcgga
      601 cacttttact gtgaattaaa tctactaaat tacttaaact tttcccccaa gaaaagccaa
      661 ttttcatatt atcatcaatt agattcctaa ggacacctgc tgcaacttga gaaattcttt
      721 cagataaaat tgttggatta tcatcaaatt catttggaat aatttctaaa ctttccagac
      781 catatttttc ttttacataa ttttccaact taaacatatt ggtatcaaaa ttctctattt
      841 caattttaac aattcctgca ttccttgctt ctgttaacat tctactaata gaggttctat
      901 aaattcctaa ttttgctgct atttgtgact gatttaagtt ttcaatataa tacagataag
      961 caattttaga gagcagttta ttcctatctt gattcataca cttaacctct tacgaaacta
     1021 ccttaaccat tatcccagca ttttctaatg tagctatatt ttgtttagaa agtttttcgt
     1081 ctgttattac ttcatagact tgacttaaag caaatcttct tactgtaccc cttttatcaa
     1141 atttacttga gtcagttagt acaatgactt tatccgatgc tgctgaaata tattgaacta
     1201 cctcactgcg cattaaatct tttcctgtaa agcccatctc tttatcgtaa ccatctgtcc
     1261 caacaaaagc ttgatgcaca tgaaaagtct gtatcatttc ttttaataaa ggtcccacag
     1321 taacctgtga atccttctga aactctccac caagaacaat aatacgacat gaatcataag
     1381 ctctcacaaa atttgctata aaaaatgaat ttgttacaat cgtaacattt cttttttgct
     1441 tgcaaatttc ctcagcaagt aaagcacagg tcgatccaga ttctatcatt attgtttcat
     1501 tatctgacac caattttact gcttcctgaa caatttttct cttaatttca taattaattg
     1561 acaaacgcac atttaagtca tctccactat ttaatacagc atatccatgc tctctgtgta
     1621 ataaaccttt tgactctaat ttatctaaat cttttctaat cgttactttc gatacattta
     1681 atttttccga taatgtatta acgtcgatct tttcatattc tgatactaat ttaataattt
     1741 gttccaatct tttcatttta cacccccgtt ttattctacc aaaataaaaa gcaaaaaaca
     1801 acaaattaac ctttcgttcg taattgtttt tctttcgttt ttgtgatagg atagacttat
     1861 gaagaggagg aactcttatg gaaatatcta aaggaattat ttttaatatt caacactttt
     1921 caattcatga cggcccgggt attcgtacaa ctgttttttt aaaaggatgt cctctgcgct
     1981 gtccatggtg ttctaatcct gaatctcaaa gaatgaaacc tgaaaaaatg aaagatgctc
     2041 aacgagagaa attcacctta gtcggtgaag aaaagactgt agaagaaatt attacagagg
     2101 tattaaaaga caaagaattt tacgaagaat ccggtggagg tttaacttta tcaggaggtg
     2161 aaatatttgc tcagtttgaa tttgctaaag ccatcttaaa atcagctaaa gaacatcaca
     2221 tacacactgc cattgaaact actgcctttg ttgatcatga aaaatttatc gatttaattc
     2281 aatatgtgga ttttatctac acagacctaa aacattataa ttctataaaa cataaaaaag
     2341 tgactggggt ttttaatcaa atgattatta aaaacattca ttatgctttt tctcaaaata
     2401 aaactatcgt tttaagaatc ccagttattc ctaattttaa caatagttta gaggatgcag
     2461 aaaaattcgc tactctattt aactcattaa atatcgacca agttcaacta ctcccttttc
     2521 atcaatttgg tgaaaacaaa tatcgtttat taaatcggaa atatgaaatg gatggaatca
     2581 acgcacttca tcctgaagat cttattgatt atcaaaaggt atttctgaac caccatatta
     2641 attgttattt ctagtttatt tccttgaaat gctctagcta tttgcagata acaagcatct
     2701 atataaggtt atcaaagaag acttccccat gactctaaat gaatatatct tacaatatcg
     2761 cctgaaacaa gctatagata agatggctga atctcccaac tcccctttaa gcgctatctc
     2821 tgaccaagtt ggattttcag actataaata ttttgccaaa gtatttaaaa agtatctcca
     2881 tatttcccca aagaaattga aatcactcgg aagaatagtc aaataggcta ttcttctttt
     2941 tgtagagaat tttactctaa tatagtgaat tgaaataaga tgtgaacatc tctatcagga
     3001 aagtcaaatt aatttataga aatattttag cagccaaagt gtactgttat agattcaata
     3061 cactatagaa tagaattgta ggttttaaaa acgcttacat tgttttaaaa taaacttaaa
     3121 taacacaacg gaggtatcca tcatgaaaaa gaaatggatg tattatgctg cttgttcttc
     3181 taatgaatct gccgatgaca gttcatctga taaaggagac ggtggttcgc tagtcgttta
     3241 ttcaccaaac tcagaaggct taattggagc aactattcct gcctttgaag aaaaatatgg
     3301 tatcaaaata gaactgattc aagctggtac tggagaactt ttcaaaaaac tagagtcaga
     3361 aaaagaagtt cctgtagctg atgttatctt tggtggttct tatacacaat atgctaccca
     3421 cggagaactc tttgaaaact atatttcaaa agaaaatgat aatgttatca aagaatatca
     3481 aaacacaact ggcttctcta ctccttatac actagatggt agtgttttaa tcgtccaccc
     3541 tgatttaact aaaggcatga acatcgaagg atatagcgac cttctcaaac ctgaactaaa
     3601 aggaaaaatc gcaactgctg acccagcaaa ctcttctagc gcctttgctc aattaacaaa
     3661 tatgctacaa gctcaaggtg gttacaaaga tgataaggct tggtcttatg taaaagatct
     3721 tttcacactt attgatggta tagtaaaatg aaataagaat aggacaaatt aatcaggaca
     3781 gtcaaatcga tttctaacaa tgttttagaa gcagatgtgt actattctag tttcaatata
     3841 ctataaaatc ggtttaagtt catctggtgt ctataaagca gtcgctgatg tagaaatgac
     3901 tgttggtctc tcttatgaag atccagcagt taaactctta aatgacggag ctaacattaa
     3961 ggtagtctat ccaaaagaag gaaccgtctt cctacctgct agtgctgcta tcgttaaaaa
     4021 atctaaaaat atggaaaatg ccaagaaatt tatcgatttt attatctctc aagaagtaca
     4081 agatacactt ggtacaacca ctactaaccg tcctgttcgt aaaaatgcta aaacaagcga
     4141 aaacatgaaa ccaattgaca aaatcaaaac actcactgaa gattatgatt atgtcatcaa
     4201 gaataaatca gatatcgtta agaaatacaa cgaagtcttt acagatatcc aatctaaaca
     4261 gtaaaagagg ttcactatga gtgagatcga aattattaac gccaaaaaaa tctaccacga
     4321 tgtccctgtt attgagaatt tgaacattac aattccaaaa ggaagtctct ttacccttct
     4381 tggagcttca ggatgcggga aaacgaccct tcttcgtatg attgcaggtt tcaacagtat
     4441 caatacttcg atgatacaaa aatcaataat atggaatcca gcaaacgcaa tatcgggatg
     4501 gttttccaaa actacgctat tttcccacat ttgactgtcc gagacaacgt tgcttttggt
     4561 cttaagcaaa agaaggttcc aaaagaagaa ttgattcaac agaccaacaa gtatcttgaa
     4621 ctcatgcaaa ttgctcaata tgcggatcga aagcccgata aactcagtgg tggacaacaa
     4681 caacgtgtca ccttggcatg cgccttagcg gttaatccaa gtgttctcct catggacgag
     4741 ccacttagta atctggaggc caaacttcgc ttggatatgc gtcaagccat ccgagaaatc
     4801 caacacgaag tgggaattac aactgtttat gtaacccacg accaagaaga agccatggct
     4861 atttcagacc aaattgctgt tatgaaagat ggggtgatcc aacaaatcgg ctgaccaaaa
     4921 taactctatc ataaaccagc taatgagttt gtggcaacct ttatcggacg cacaaatatt
     4981 atccctgcca atcttgaaaa acggagcgac ggcgcttata tcgtcttttc agatggctat
     5041 gcccttcgaa tgccagctct tgatcaggtt gaggagcaag ctattcatgt aagcattcgt
     5101 cccgaagagt ttatcaaaga taaatctgga gatatcgaag gaactattag cgatagcgtc
     5161 tatcttggac taaatacgga gtatttcatt gagacaggtt ttgcctcaaa aatttaagtt
     5221 agtgaagaat caacttttga agaagaacta caaaaaggca atcgtattcg tctacgaatc
     5281 aatacgcaaa aattaaacat cttttctgca gatggttccc aaaacctgat aaaaggagtc
     5341 aaccatggaa tgtaaaaaac taaatatttg gacagcttcc tctttcttca tctttcttac
     5401 ctatcttgtc tttctcgttt atcctatcgt taccgtgctc aagcaagcac ttatacatga
     5461 aggacaattc tcactagcta attttgtcac tttctttagt aaagcctact actctgagac
     5521 actagtcaac agtttcaggg tttccattac cgctactgtc acttccttag ttgtaggaac
     5581 cctattagct tatctcttct ctatgtatga cttcaagggg aagaaatttc tacaaatatt
     5641 gattatcatt gcttccatgt cagctccttt cgtaggagcc tactcctggg ttctcttgct
     5701 gggacgaaat ggggtcatca ctaaattttt gacaaatgcc cttcatcttc cagctatcga
     5761 tatttatgga ttcaaaggaa ttgtacttgt ctttacactg caactattcc cactggtatt
     5821 tctatatgtt gctggaacaa tgaacagtat tgacaattct ctacttgaag cagctgaaag
     5881 catggggtcc ttcggattta aacctatcgt aacggttgtt ttacctctcc tagttccaac
     5941 cttactagca gctccttgct tgtatttatg agagcattct cagactttgg aacgcctatg
     6001 ttgattggcg aaggatatcg gactttccct gtcctgattt atacccaatt tattagcgag
     6061 gttggaggaa attctgcttt tgcaattatg gcgattatca ttgccttggc aattttcctt
     6121 atccaaaaac acattgcaaa ccgctacagt ttcagcatga atctgctcca tccaattgag
     6181 cctaaaaaaa ctacaaaagg aaaaatggct gccatttatg caacagtcta cggaattatc
     6241 tttatctctg ttttacctca aatctactta atttatacct ctttcctaaa aacatcaggt
     6301 atggtatttg ttaaaggtta ttctccaaac agttacaagg tagctttcaa tcgtatggga
     6361 tctgctattt tcaataccat tcgtatccct ttgattgcct tagttctagt tgttctattt
     6421 gcgacattta tctcctacct agccgttaga aaacggaatt tgtttacaaa cttaattgac
     6481 agcctcagta tggtacctta tattgtacca ggaaccgttc tagggattgc cttcatttct
     6541 tccttcaata ctggtctatt tggaagtgga tttcttatga ttacagggac tgctttcatc
     6601 ttgattatgt ctctatctgt cagaagatta ccgtatacta ttcgctcatc tgttgctagc
     6661 ttacaacaaa tagcaccaag tattgaagaa gctgctgaaa gcttaggaag tagtcgtctc
     6721 aatatctttg ctaagattac aactccaatg atgctatcgg gtattatttc tggagtcatc
     6781 ttatcttggg tcacaatgat ttcaaaactc tctacttcta tcctcctcta caatgtcaaa
     6841 acaagaacaa tgactgtagc tatttataca gaggttctca gaggaaatta cggtgtagcc
     6901 gcagccttgt caactatcct gactgttcta acagtaggtt ccttgctctt gtttatgaaa
     6961 atctctaaaa gcaatagctt taccctttag ttttccacat caaaaacagc cgaaaggagt
     7021 gccctcggct gttttttctt atcttgatat tcttatcaaa tccctagctc atggcaagca
     7081 agtctagact gattaaatag agccttcttc catcttctca cgtcctagct ctcggtaact
     7141 acggtcaccg acaacttcaa ccctaaactg accgccctca tattcaagaa tcgtcacgct
     7201 accattatct agaccatgcg gatgcatgcc attaatcaga taaacaatgg ttccaatagt
     7261 cattccatgg ctgacaacaa gggcgttacc tccaccttga tcttccattt cttttgcaat
     7321 catttcaaag ccttccttga ttcggccact gagtttttcc cagccttcag cccaaccagc
     7381 tgtatcgacc tctaccaagc cctcagccag ttcagcataa gacaattggt gaacgtggtc
     7441 cacattaaag atacgaggaa taatgcccat gaaaagatcg ccatcatagg ctccatcaaa
     7501 actaccgaaa caccattctc tgatacgctt gtccatgcga taagggattt tcccctgcaa
     7561 gccaagctct tcaaggataa ttcccatggt ctgaatggta cgaccagaat cactcgaata
     7621 agcgcgctca aactgtagat cagattctcg caaaccgatt cctaactctt gaatccctcg
     7681 ttcaccttca gcagttaagg gagtatcgct ccaaccttgc gcgcgaccaa tcgtgttaaa
     7741 catggtcttg ccatgacgta ccaaatacaa tcgtactttt accattttcc gtcctccgtt
     7801 tgcttctatt atatcatgaa tgataaaata aaagccaccc atacaggcga cttttgaagg
     7861 agattattat gaaaaagttt aggagttcat taaataaaga tattagatga aaatcaaatt
     7921 caaactaatt caatgttatc tgtttcaaat aatattagga ggtctttatt taatgattat
     7981 agtatacacg tctaatctta aatagaactt aaaatttctc ctattttctt aatttttaaa
     8041 actatgaatt ggtgctggga tttgtccacc gcgagagatg aagtcgacag acgaagcccc
     8101 attaaccctc ataacgggtg cagttcctaa tagaccacca aactcaatca tatcgccttc
     8161 ttttcctttg ggaatgatac gaacagctgt tgttttcatg ttgataacac cgattgctgc
     8221 ttcatccgca atcatagccg caatggtttc agcaggcgta tcttctggga tggcaatcat
     8281 atccaatcca acagaacaga tagccgtcat agcttctagt ttttctaaat taagagagcc
     8341 attttgcact gcagcaatca ttccttcatc ctcagaaaca gggataaagg caccagataa
     8401 accaccgact tggttgcagg ccatcactcc acccttttta acttggtcgt tcaagagggc
     8461 caaggcagcc gtcgttccat gcgtgccaac tgtttctagc cccatttcct caaggacacg
     8521 tgccacagag tctccaaccg caggggttgg tgccaaactc aagtccacaa taccaaactc
     8581 cacacccagt ctctcactgg ccatttgacc aaccaattga ccgatacgag tgattttaaa
     8641 ggcagttttc ttaactgttt cggctactac atcaaagctc tgtccacgaa ctttttccaa
     8701 agcacgtttc accacaccag gaccagaaac tccgacattg atgataacat ctgcttcccc
     8761 aacaccatga aaggcacccg ccataaatgg attgtcctca acagcattag cgaatacaac
     8821 caacttggcc gctcccatat ctgaaagatt tgccgtttcc ttgataattc gtcccatatc
     8881 tgccacagcc gtcatattaa taccagactt ggttgagccg atattgactg acgagcagac
     8941 cttatccgtc tcagtcaaag cgcgaggaat ggaattgatg agaatctcat ctcccttttg
     9001 ataacctttt tgtactacgg cagaaaaacc accaataaag tccacaccaa tctctttcgc
     9061 agccttatca agcgcttttg ccagaaccac gtagtccgtc gcatctgtcg ctgccccaat
     9121 cagagaaata ggtgtcaccg atacacgctt attaacgata ggaattccca actcagccgc
     9181 aatttcatca ccaacagcta ctaaattagc cgcctttgtc gtaatttttt gatagatttt
     9241 ctccgcagca cgattgatat ctggatcgat acagtccaaa agagaaatcc ccatggtaat
     9301 ggttctaata tcgaagtttt gctcctcaat catggcgatg gtttcagtaa cttgtctaat
     9361 atccatgatg acctcctaga tattatacat agcttcgaaa atcgctgcac tctgaatatt
     9421 gatttttaca ttcaaagttt gcccaaaagc ttcaaattca ttacgaagat aggtaaaatc
     9481 ttgcttttca tcactagata caacagccat catcgtaaaa tattcatcca agacagtttg
     9541 agagatatcg tcaatattca atcctaattc tgcaatttta ccagaaacac ctgcaacaat
     9601 tccagattta tctttaccaa caacagttat aatggctttc ataagtaaac tccaattctt
     9661 cttaaaataa gaaaccttaa cattaaacag gattcttttc aaatagtata gcataattct
     9721 aacgaaaata ctcaaaaacg cctgcttacg aagttgttct taagaaaaaa acaatttcgt
     9781 aaacaagcgt ctactatccc aacttatgat gagtgttccc gctaggaccg aaatcctagc
     9841 ggtagaccag agctagacta agagcacaag actccatcat cataacactc aacaaaattg
     9901 atgattttat actaattcga tgatcgccat tggcgctgca tcaccacgac gtggttcagt
     9961 tttaaggata cgagtgtatc caccgttacg ttcagcataa cgaggtgcga tttctgagaa
    10021 caatttttga agtgctgtag tagaagtgta cttatcagtt gcttcatcat agttttcaga
    10081 tgcgatttca ttacgtacga aagcagctgc ttgacgacgt gcatgcaaat caccacgttt
    10141 acctagagta atcatttttt caacagtttt acggatttct ttagcacgag cttcagttgt
    10201 cacgattgat tcgttgatca aaaggtcagt tgtcaaatcg cgaagcattg ctttacgttg
    10261 tgagctagtg cgtcctagtt tacggtaagc catgtattcc tcctttattt atcttttaat
    10321 ccaagaccca aatcaatgag tttgagtttc acttcttcca aactcttgcg tccaagattt
    10381 cgtactttca tcatctctgc ttcagatttt tctgtcaaat catgcacagt attgataccg
    10441 gcacgtttta aacagttgta tgaacgcaca gacaagtcca gttcctcaat cgtacgatct
    10501 aaaatacggt cgtcagattc agtatcagct tctttcatca cttcagttga cttagcaatc
    10561 tcagtaagat ttgtaaacaa atcaagatgt tctgtcaaaa tacgtgctga aagccctaaa
    10621 gcatcttctg gaataattgt tccatttgtc aagatttcaa gggttaattt gtcgaaacca
    10681 tcattgctac ctacacgagc aggttccact tgatagttga cttttgtaac tggtgtataa
    10741 atagaatcta cagcaagtgt tccaactggt gcattatcct ttttattttc atcagcaggt
    10801 acatatccac gaccactgtt aacagtcata gtcgctttta gagaagaacc ttcaccgatt
    10861 gtaaagagat aatgatctgg atttacaatt tcaatatcgc tatctgtcaa aatgtcacca
    10921 gctgttactt cagcaggacc ttcaacatcc agttcgatga ttttttcgtc ttcaacgtac
    10981 gatttcactg caattccttt aatgttcaga atgatttgca tcacgtcttc acgaacacct
    11041 ggaactgtgt caaactcatg taacacacca tcaatgttga tagatgtcac agctgctcct
    11101 ggtagagaag ctagaagtac acgacgaaga gagttaccaa gagttgtacc gtagccacgt
    11161 tcaagtggtt cgattacaaa cttgccataa tctttatttt catcaatttt tgttatattt
    11221 ggtttttcaa actcgatcat ttagttactc cctcttaaac gaaaagcagt gtaatgcgat
    11281 gattatacac ggcgacgttt tggaggacga gcaccattgt gtggcactgg agtcacatca
    11341 cgaattgctg ttacttcaag accagcggca gcaagcgcac gaatagctga ctcacgacca
    11401 gaacctggac cttttacagt aacttcaact gatttaagac cgtgttcttg tgcagattta
    11461 gcagcagctt cagaagccat ttgagcagcg aatggtgtag atttacgaga acctttgaaa
    11521 ccaagagcac cagctgatga ccaagcaatt gcattaccat gcacatcagt aatcataaca
    11581 atagtgttat taaatgtagc gtgaatatga gcaataccag attcgatatt ctttttcaca
    11641 cgacgtttac gtgttggttt agccaagact tttacctcct atattatttt ttcttaccag
    11701 caatcgcaac agctttacct ttacgagtgc gagcgttgtt tttagtattt tgtccacgga
    11761 caggaagtcc acgacggtga cggataccac ggtatgaacc gatttccatc aaacgtttga
    11821 tgttcaagtt tacttcacga cgaaggtcac cttcaacttt gattgcatcc acttcacgac
    11881 ggatagcatc ttcttgatct gatgtaagat cacgtacacg aacatcttct gagattccag
    11941 cagcagccaa aatcttctta gatgttgcaa gtccgatacc ataaacataa gtcaatgaga
    12001 ttactacgcg tttgtcattt ggaatatcaa ctccagcaat acgagccatg ttttctcctt
    12061 tctatcttat ccttgacgtt gtttgtgttt tggatttgct gggcaaatta ccataacacg
    12121 accattacga cgaataactt tacagtattc gcaaattggt ttgaccgatg gtcttacttt
    12181 catttcttat ccctccaagt ttttcgatta tttaaagcgg taagtgatac gtccacgtgt
    12241 caagtcatat ggactcattt cgacagtaac acgatctccc gctaaaatac gaatatagtt
    12301 tttacgaatt ttaccagaaa ctgttgctaa aatctgatgt ccattttcaa gttcaaccgt
    12361 aaacattgca ttcggcattg tatcaactac tttgccttca acttcaatca catcgtcttt
    12421 tgccacgcaa aagcacctcc ataaatttcg attcgatgcc tctagacaca gagacaacaa
    12481 ttataagtca gactatctca gtataacatt tgtagcggat ttttgcaagt gtgaaaaacg
    12541 ctttatttca aatttgtcaa tactttttca atatctgaga agacatcatt gatatcttga
    12601 ttaccttcga tgtcatgaac caaacctttg gcacggtagt gagcaatgat tggttctcct
    12661 tgagcaatat taacatccaa acgacgtttt actgtctcag gcttatcatc ttcacgttgg
    12721 tagtagtctt cttctttata gtcaactggt gggttaaaga ccttgtggaa agtttctcca
    12781 gttacgcggt ggatgatacg gccactcaaa cgttccaaga ggctgtcagg gttcacttca
    12841 atattgataa caccttctag ttcaatgcca agttcagcca atgttttgtc caaggcatga
    12901 gcttgttcaa ttgtacgtgg gtaaccatcc aataagaatc ctgtttcttt aatatcatct
    12961 tgtgaaagac gttcttttac gattccattt gtaacttcgt caggaaccaa ttcacccttg
    13021 tcaatatatg acttagcaag aacacccatt tcagtttgat ttaccattgc agcgcggaac
    13081 atatcacctg ttgagatatg tgcaacatgg aattgttcta cgatttttgc tgcttgagtt
    13141 cccttacctg caccaggtaa gcccataatc aaaagattca tgatttgatc tccttatttt
    13201 atttttaaat agaagcaaaa agtcttttca cccctattta aaaacaaaat agaagagggg
    13261 agatccaact cttacaaatg tcagagttta aacctccact ccctcagtat ttactgattc
    13321 agtaaatact tttattctgt tttgtccatg aaaccaacat acttacgttt caataggtaa
    13381 ccttccaatt gcttgattcc ttcgatacct gtagagataa tgatcaagag acttgttcca
    13441 ccaaaggcaa caacatcaga aagaccaaat acatctttag ctgcaatcgg taaaatggaa
    13501 atcacaccaa ggaagaggga accaacagtt gcaagacgac gaagaagttt agacatatat
    13561 tcttctgtac ctttaccagg acgaactcca tggatatagg caccactctt ttgtaggctc
    13621 tctgctgctt tttcaggatt aatctgtaca aacgtataga agaatgtaaa gagaataatc
    13681 aacaaagcat acatggcaat accagttgga gaagtagttg ccaacatctc ttgtgctacc
    13741 cttacccaag cccaatcatg acctgtggca ctcaaaaact gaagaatagc cgcaggcgct
    13801 gcagtaatcg aactggcaaa gataacaggg ataactccag caggatttac ctttaacgga
    13861 aggtaagagc tagatggagc accttgtgca accttagtat attggatcgg aattttgtat
    13921 tctgcttgtt gaacataagt tgtaaagtaa ataatcaaca atacagtaat aatcaaaatg
    13981 attacgaaaa tgatagatga agtgatacgg ctacttggga cgttcacaaa gtagtccaca
    14041 tagatgccct gaatcatctc tggaattgag gaaacaatcc cggcaaagat aatcatggaa
    14101 acaccgtttc cgtatccctt atctgtaatt tgctcaccca accaagtgac aatcatacta
    14161 ccagctgtta agatgatacc aatcgtcaga aaaacttgtg gagttaaagc agttttaatc
    14221 aattgagctc cagccaaggt attaaaacca gctgtaatcc cgatagattg cacaaaagcg
    14281 agaactagag caatataacg agtagcttga ttcaattttc ttcgacctac ttccccttgt
    14341 ttaccccact ctacaaactt gggtaaaata tccatttgca agagttggac aacaatagaa
    14401 gcggtgatat agggactaac tcctagggca aaaatcgaaa agttttttag ggcattcccc
    14461 gacaccaagc tcaacatgtt taagaaggat aatccactta aagcattcaa gctattggca
    14521 ttcacaccag gaactgtaat gctagttccg atacgaaaga ccaaaacgat aaaaattgta
    14581 aataaaattt ttgatcgaac ctgcttgact ttaagagctt ctcttaataa tttaaaaaac
    14641 ataggtcacc tctcttagat gacttctact gaaccacctt tagcagtgat agcttcttca
    14701 gctgatttag agaatttagc tgctttcaca gtcaatttct tagtcaactc accgttacca
    14761 agaattttaa tacctgactt ttcagcttta acaattcctg cttcgataag aacaactgga
    14821 gttacttcag caccatcttc aaagacgttc aattggtcaa ggttcacaat tgcgtattct
    14881 ttagcgttga tgttagtgaa tccacgtttt ggaagacgac ggaacaatgg agtttgtcca
    14941 ccttcaaaac caaggcgaac tccgccaccg ctacgagctt tttgaccttt ttgaccacga
    15001 ccagatgttt taccgttacc tgatgaagta ccacgaccaa cgcggttacg tactttacga
    15061 gaaccttctg caggtttcaa ttcatgaagt ttcattttta ttttctcctc ttttgtaaaa
    15121 tgctagcgcc gataagggag aaaaggttgt ctcccccatc aactcgccta tacgatgtca
    15181 tcatagatga ctatatctag ttttagggga tggtacagtg cacatcccct aaaacttcat
    15241 tagtttactt cttcaactgt tactaagtga gatactgctg tgatcatacc acggatagca
    15301 gcgttatctt ctttaataac agagctgttc aatttgccaa gtccaagtgc tacaacagtt
    15361 ttacgttgtg atggaatgcg tccgattgga gacttagtca aagtaatttt aatttgagcc
    15421 attttatccc ctttcttatg ccaaatcaga aactgaaata ccacgaaggg cagcaatttc
    15481 ttcagcgcgt ttcaattgtt tcaaaccttc aacagttgca cgaacaatgt tgattggagt
    15541 gttagaacca agtgatttag atgtaatatc tgccacacct gccaattcca caacggcacg
    15601 aactgcacca ccagcggcaa ctccagaacc ttctacagca ggtttcaaca atactttagc
    15661 tccaccgaat tctgaaagaa cttcgtgtgg gattgttgtt ccaaccatag gaacttcgat
    15721 caagtttttc ttagcatcat ctactgcttt acggattgct tctggaactt cttgagcttt
    15781 accagtacca aatcctacgc gaccattgtg gtcaccaaca acaacaagag ctgcgaaacg
    15841 aagacgacgt ccacctttaa caacttttgt aacacggttg acagcaacta cgcgttcttc
    15901 taattcaact gcattgtctt taaatgccat tttctagtgt cctcctatta gaatttcaat
    15961 ccgttttcac gagctgcatc agccaaagct ttcacacgtc cgtgatatag atatccaccg
    16021 cggtcgaaca ccacttctga aataccttta gcgtttgcac gttctgcaac gagtttaccg
    16081 acagcaacgg cttgttcagt tttagttcct tttgaaactt ctttatcaag agttgaagca
    16141 cttgcgagcg ttacacccgc tacgtcatca atcacttgag cgtagatgcc tgtattagaa
    16201 cggaatacgt tcaaacgtgg gcgatcagca gttccagaga gttttccgcg aacgcgacgg
    16261 tggcgttttt ggcggagttt gtttttatct ggttttgaaa tcacagtttt cacctcttta
    16321 gttttaaatc gtgtgctatg cacaaagttg gaaaataggt tggtggttga tgatcaacca
    16381 ctcaacatta tttacctgtt ttaccttctt tacggcgaac gaattcacca acgtaacgga
    16441 tacctttacc tttatatggt tctggtgaac gaaggctacg tacgtaagca gctgtttgac
    16501 caactacttc ttttgaaatt ccgctaacaa cgattgttgt tgggtttgga agttcaaaag
    16561 taattccttc tggagcttca acttcgtctg gatgagattt accaacagcc aaaacaagtt
    16621 tagatccttg aagctgtgca cggtaaccaa ccccacgcat ttcaagttct ttcttgaatc
    16681 cttctgatac accaacaacc atgttgttca aaagggcacg agtagttccg tggatagttt
    16741 tcatttcttt tgaatcgttt ggacggtgaa gagttacttc agtaccatcc acacggattt
    16801 caatatcttt tgagaactca cgagtaagtt ctcctttagg tccttttaca gttacaacgt
    16861 tgtcattgtt agcgagttca acaccagcag gcaacacgat aactttatta ccaatacgtg
    16921 acatgtttat tttctcctgt taaattgtca ggccagaacg gccagttttc acggggttca
    16981 gatacttatt tagttcaaga gctgaactga acacgctcta agaactgtgc aaaatagata
    17041 agttggcttg tttgtaaaca aacttctcca acttcctaat tttgctttgt tctttacgag
    17101 ctttgtatct tgattttacc aaacgtaagc aataacctca ccaccaacat tcttttggcg
    17161 tgcttcttta tcagtaagca aaccttcaga agttgaaagg atggcaattc caagtccgtt
    17221 aagaactttt ggaaggtctt cacgtttttt gtagacacga agtcctggtt tagaaacacg
    17281 tttcaagtta gtgataactt tctcaccatt tggtccgtat ttaagaaata cacggatgac
    17341 gccttgtttg tcatcttcaa tgatttcaac gttttttaca aaaccttcgc gtttaaggat
    17401 ttcagcaatc ccttttttga tgtttgatgc aggtacttca agtacttcgt gtttagcttg
    17461 gttagcatta cgaatacgag ttaggaagtc tgcgattggg tcagtcataa ccattttgtt
    17521 tttctcctct tactagtagt ttgcaagttg cacttgctag ttaatgattg agctgggctc
    17581 agatagtatt gacacattca aatgagagaa ctcttatttg aacacgagct acaacctgtg
    17641 caaaaaagat aaatttgttt tggagcatcg ctccctcacc aaatttccta ttttcgctgt
    17701 ggttgttacg ctctttgtat catgatatta ccaagatgct tttgttacac caggaatttg
    17761 acctttatgc gcaagttcgc gaaaagcgat acgactcaga ccaaatttgc ggtaaactga
    17821 atgtgggcgc cccgtaactc tacaacgatt atgtaaacga gtcggtgagg cgttgcgagg
    17881 taatttagat aaaccttcgt agtcccctgc cgcctttaat gcagcacgtt tttcagcata
    17941 acggtcaaca attttttggc gtttagcctc tctagctacc attgattttt tagccattag
    18001 atttacctcc tatattattt tgcaaaaggc attccaaggc ctgtaagcaa tgcacgtgac
    18061 tcttcgtcag tgttagcagt tgttacgata acgatgtcaa gaccacgagt tttgtcaacg
    18121 tcatcgaagt tgatttctgg gaagattaat tgttctttca caccaagtgt gtagttcccg
    18181 cgtccatcaa atgattttgt tggaacaccg tggaagtcac gtacacgtgg aagtgaaact
    18241 gataccaatt tatccaagaa ttcgtacata cgttcaccac gaagggtaac ttttgcaccg
    18301 atcgcaacac cttcacgaag acggaagccg gcgattgatt ttttagcttt agtgataagt
    18361 ggtttttgac ctgagataag tgccaattct tcagcagctt tttcaaggct tttagcgttt
    18421 gatacagctt caccaacacc catgttcaaa acaatcttat ctactttagg cacagccatc
    18481 actgatgagt agttgaattg ttctgtcaaa gcaggaacta cttcattaag atatttttct
    18541 tttaaacgat ttgccattat acttctcctt tccttcgtga ttaatcaagc acttcgcctg
    18601 attttttgtt gtagcgaact tttttaccgt ctacaaattt gtaaccaaca cgaccagcta
    18661 caccattttt gtccaaaact tgaacgtttg atacgtggat agctgcttct ttctcgatga
    18721 taccaccttg aggaagctcg ttagttggac gttggtgttt cttaacaatg ttaacacctt
    18781 caacgataac tttgtttact tttggaaggg cagtaaggac aacagcttct gttcccttat
    18841 ctttaccagc gattacgcga actttgtcgc ctttttttac aaacattagg tttctccttg
    18901 atttttctta cgcccataag ggcaccctag cttgaagcta ggggactagt ttgttcctaa
    18961 aaattaaagt acttctggag caagtgacac gatcttcatg aagccacctt cacgcaattc
    19021 acgtgcaact gggccaaaga tacgtgttcc gcgaggagtt ttgtcttcac ggatgataac
    19081 tgctgcgttt tcgtcaaatt tgatgtatga accatcagca cgacgagcac ctgatttagt
    19141 acgaacgata actgctttaa caacgtcacc ttttttaacc gcaccaccag gagtagcttg
    19201 ttttacagat gccacgataa catcaccgat gtttgcaaat ttacgtcctg aaccaccaag
    19261 aactttgata gtcaagattt cgcgagcacc gctgttgtct gcgactttca aacgagtttc
    19321 tgtttgaatc atttcagttt tctcctttca ggtttgatta gatgatgacc gcttcttcaa
    19381 caacttctac aagacggaaa cgttttgtag ctgaaagcgg gcgagtttcc atgatacgta
    19441 cgatatcgcc ttctttggca acattgtttt catcatgagc tttgtatttt ttagagtagt
    19501 taatacgttt accatagact gggtggttac gttttgtttc aactacaact gtgattgtct
    19561 tgtccatttt gtcagataca acacgtccaa caagaacttt acgattattg cgttccattg
    19621 aaatttctcc ttccctagtc tattatttcg cttcagattg aactgttttg atacgagcga
    19681 tttgtttttt aacttctttc aagcgaactg tttgttccaa ttgaccagta gcagcttgga
    19741 aacgaagttc aaacaattct tttttcaatt cgttttcgcg cttcgcgagt tcttcttgag
    19801 aaagaccacg aagttcttta acaaattctt ttacttcatt aagtttcatg ccttctcctt
    19861 attctgcttc acgttttacg aatttacatt taactggcaa tttgtggcta gcaagtcgaa
    19921 gcgcttcacg tgcaatctct tcagatacac cagcgatttc gaacatcact ttaccacgtt
    19981 taactggtgc tacccaacct tcaggtgccc ctttaccaga tcccatacgc acaccgatag
    20041 ctttagcagt gtatgatttg tgtgggaaga ttttaatcca aactttacca ccacgtttca
    20101 tgtaacgagt catggcgata cgagcagctt cgatttggcg gttagtgatc cagtggctag
    20161 ttgtagcttg aagaccgtat tcaccgaatg ctacttcttt tccacctttt gcttcaccgc
    20221 gcatttttcc acggaattca cgacggtgtt taacacgttt aggtactaac attggttatt
    20281 tacctccttt agtgttttta cgagctggaa gaacttcacc acggtagatc catactttaa
    20341 caccaagttt accgtatgta gtatctgctt cttcccaagc gtaatcgata tctgcacgaa
    20401 gtgtgtgaag cggaacagtt ccttcagagt atccttcagc acgggcgata tctgcaccgt
    20461 tcaaacgacc tgatacttga gttttgattc ctttagctcc agcacgcatt gcacgttgga
    20521 ttgcttgttt ttgtgcacga cggaaagcaa cacgttgctc caattgacga gcaattcctt
    20581 cacctacaag gtgagcatcc aaatcaggtt gtttgatttc gatgatgttg atgtgtactt
    20641 gttttccagt caatttgtta agttttgcac ggagtgcatc aacgttagca ccacctttac
    20701 cgataaccat acctggttta gcagtgtgaa gtgaaacgtt aactttgttt actgcgcgtt
    20761 cgatttcaat agttgaaact gctgcgtcag caagttcttt ttgaacgaat ttacggattg
    20821 caagatcttc atgaaggtaa tccgcgtatt ctttttcagc ataccatttg gcatcccaat
    20881 cacggatgat gccgacacgc ataccaattg gatgtacttt ttgacccacg attttacctc
    20941 cttatttttc tgcaacagct acagtgatgt gagctgtacg tttgttgatt ggtgaagctg
    21001 aacctttcgc acgtggacgg aaacgtttca tagttggtcc ttcgtttgcg aatgcttcag
    21061 atactaccaa gttagcttta tccaaaccaa agttgttttc agcgttagct acagctgagt
    21121 tcaaaacttt caagatgatt tcagcagctt tgtttggagt gaatgtcaag attgcgattg
    21181 catcggctac gcttttacca cggatgttat caagaacaag acgtgattta cgaggtgaaa
    21241 cacgtactgt acgagccatt gctttagctg aagtaatttc tgccatttat gttctcctta
    21301 ttttctacgt gttttcttgt cgtctgcagc gtgacctttg taagtacgag ttggtgcaaa
    21361 ttcaccaagt ttgtggccta ccatgtcttc ttggatgtaa acaggtacgt gtttacgtcc
    21421 gtcataaact gcaatagtgt aaccaatgaa acttgggaag atcgttgaac gacgtgacca
    21481 agttttaata acttttttct tttcgtcgtt agcttgagct tcaacttttt tcatcaaatg
    21541 ctcatcgacg aaaggtcctt ttttaagact gcgtcccatt tttatatttt ctcctttaaa
    21601 tgttgtacca cagcggcttg cactcctatg gagcgctacc gagctggcgg atttactagt
    21661 tgcttaagcg actagtctaa tattatttct cgttgcgacg acgaacgata agtttgtcag
    21721 atttcgcttt cttgttacga gttttaagac caagagcagg tttgccccat ggagtagatg
    21781 gtgctttacg accaactggt gctttacctt caccaccacc gtgtgggtga tcgttagggt
    21841 tcattacaga accacgaact gttgggcgga tacctttcca acagctacgt cctgctttac
    21901 caaggtttac aagtccatgt tgttcgtttc cgacaacacc aactgtagca cggcaagttc
    21961 caagaatcat acgaacttca cctgattgaa gccgaacaag aacatattta ccttcagaac
    22021 ccaatacttg agcagatgca ccagcagcac gtaccaattc accaccacga cctggtttca
    22081 actcgatgtt gtgaatcaaa gtaccaactg ggatgttagc aagtggaaga gcgtttccga
    22141 ctttgatatc tgcttctgga cctgaaacga tacgttgacc tacttcaaga ccttttggag
    22201 cgatgatgta tgctttcaca ccgtcagtgt agtgtacaag agcgatgttt gcagaacggt
    22261 ttggatcgta ctcgattgtt ttaacaactg cttcaacgtt gtctttatta cgtttgaagt
    22321 caaccaaacg gtagaaacgt ttgtgtccac caccttggtg acgaactgtg atacgaccgt
    22381 tgttgttacg accagccttg ctcttcaatg caacaagcaa tgatttttca ggagtgcttg
    22441 ttgtgatttc agcgaaatcc aaagaagtca tattacggcg accgtttgtt gttggtttat
    22501 aaacacgaat tcccacgata tttcctcctt agattattca gcttcagcag caaacaactc
    22561 gattgcttta gaatcagctg taagtgtgat gatagctttt ttagttttgt tagtaaaacc
    22621 agtgtaacgt ccaacacgtt tagcttttgg ttttacgttg attgtgttaa cattggcaac
    22681 tttaacacct tcgaaagcag cttcaacagc ttgcttgatc aaaagtttgt gtgcacgagt
    22741 gtcaacttca aatacatatt tccctgcttc aagttgagcc attgagcttt cagtgatgac
    22801 aggttttttg ataacatcat acaaattcat tatgcaagaa cctcctcgat tttagagata
    22861 gctgcttgtg tgacaagaag tttgtcgcta tttgcgatgt caagaacact tgcagttgta
    22921 gcagttgcaa ctttcacgtt tggaaggtta cgagctgaaa gagctgcgaa ttcatttcct
    22981 tcttcaagga taacaagaac tttagaatcg atgctcaatg ctgcaagaac ttttgcaaat
    23041 tcagcagttt ttggagctgt aaatgaaaga gcgtctacag ctacgaattt gttttcagca
    23101 actttttcag agtaaactga tttaagagct aggcgacgaa ctttttgtgg aagtttgtag
    23161 ccgtatgaac gtggagttgg tccgaagaca acaccaccac cacgccattg tggtgagcgg
    23221 atagaacctt gacgagcacg tccagttcct ttttgacgcc atggtttgcg tccaccacct
    23281 gatactgcag agcggttttt aacagcgtgt gttccttgac gaaggcttgc gcgttggctg
    23341 atgattacat caaacacaac tgattcattt ggttcgatac caaatactgc atcgctaaga
    23401 acaacttggc cagcttcttt accagtttgg tcaaataatg ttacgtttgc cattgtgact
    23461 gatttcccct ttctttatta tttaccagct ttaactgctg atttgatagt gataagagat
    23521 ttcttagcac ctggtacgtt acctttgata aggataacgt tcttttctgg aacaacttgt
    23581 acaacttcaa ggttttgaat tgttacgcgg tcgccaccca tacgccctgc aaggttttta
    23641 cctttgaata cgcggttagg tgcaacaggt cccatagaac ctggacgacg gtggtaacga
    23701 gaaccgtgag ccattggtcc acgtgattgt ccgtggcgtt tgataacacc ttggaaacct
    23761 ttacctttag aagtacccgt tacgtcaaca acatctccag ctgcgaatgt ttcaactgtg
    23821 atttcagcgc caacttccaa gccttcaacg tttttgaatt cacgaatgaa gcgcttagga
    23881 gccgtgttag ctttcgctac atgtccttta gcaggtttgt tgctcaatac ttcgcgtttg
    23941 tcatcgaaac caacttggat agcgttgtat ccgtctgttt caacagtttt aacttgaaga
    24001 acaacgtttg gagttgcttc aataactgtt acagggatca attcgccagc ttcagtgaag
    24061 atttgagtca ttcccacttt tttccctaag attccttttg tcatgagaaa atagttcctt
    24121 ttctatattt tttattcaaa aagtttttaa cgagcgtttt ttatgctcaa gtctaagata
    24181 caaagggcgt caaactcaac gtgaaaatag gaaactgacg cagtgtctag cagacactag
    24241 gaagtttatc tttttcacac cgagtttagt ccgtgttcaa ttagattgaa acaccagcct
    24301 ctgctctttt atattttaga ttaaagtttg atttctacgt ttacaccact tggaagatcc
    24361 aatttcatca aggcatcaac tgttttttga gttgggttaa cgatatcgat caaacgtttg
    24421 tgtgtacgca tttcaaattg ttcgcgagag tctttgtatt tgtgagtcgc acgaatgatt
    24481 gtgtagaggc tacgttcagt tggaagtggg attggacccg caacttgtgc acctgtacga
    24541 gtagctgatt ctacgatttt tgcagccgct gtgtcaagcg tacggtgttc gtaagctttc
    24601 aaacggatac ggattttttt gtttgccatc tttttctcct tttcgtctat ttaagataat
    24661 aggctagctc cacaagaaaa ccgacgcggt gttgcgtggc aatgcaaccg agcgtgtcgc
    24721 aacctcttgc atcaaaacta aggctgtaat ttacagcacc ataatagaat aacacaaagc
    24781 ccctgcgatt gcaagggatt tgttgctgtt ttttcgtttt tttgggatga aactgttttc
    24841 ctactttttc tttctaaaat tagggatttt cttctatatt tcttctatac ataagttaag
    24901 tcctcttgac atcaaattta tcttctgatt ggtccactaa gatatccgcc ttagactcag
    24961 tttctttata gtatcgcaga tactgctccc gtctcatctg atggctagcc aatataaagg
    25021 atgcatcgcg atttctcaca gtcgtatctc tagcaaggcg tcgctttaat tcggtctcct
    25081 catccgtgta gaaacagatg gttttttcaa agagttcctt gggtagaaag ccaacagaca
    25141 tcccttcgac aatcaaaatt ggtttggctc cagacaagac ctcactagcc ttccaaggtt
    25201 cttcaattgt caagacatcc atacccgcct gcaaggcaag gatatctctc tgcaaactct
    25261 ccagttcatg cgccactggc agactggctg tcaccttttg attcggcgcg tccttgggta
    25321 ctaccagatg gcgtcctgag gtgatataag gatctgtctc tagcaaattt actgtagtag
    25381 aatctaaagc ttggtacaat tcctgtgcaa aggttgattt acctgaagct ccatgaccgt
    25441 atattcccag tgtcctgact ttccccgtct cgatctctga gactagttgg tctactaagt
    25501 cctttttctt cattctctct tcacctgttc atagctttct tttccgtcat tgagcttgtc
    25561 ccaaatcact acttgcccac ttttgagcga tttttgcaca tcgataattc gttggttgga
    25621 cgaacctcga aactggagca tgagatttct cttagttcga tcgtatcgtc catcgacaag
    25681 aatgtcaatc aatgataaga gttccagttt atctggagtt tccaacatca tttcttccca
    25741 agtgtagccc gtccaggacc aaatgtcctt gtctggcaat tcctttcgga tgcgtttaac
    25801 tagaggcaag agaatgccag tattgagaaa aggctcccct cccagcaaag tcaagccttg
    25861 aacatagggt tgggcaaggt ctgccataat ctgctcttct aattctgctg tatagggaat
    25921 gccagcatta aaagaccaag tcgcaacatt ataacatccc tcgcagtgaa acatacagcc
    25981 tgatacatag agagagttgc gcacgccttc gccgtccaca aagttaaagg ccttgtagtc
    26041 aatgatacga ccttgactaa gttcctcgct tttccattct tgtggttttg gattattcat
    26101 tcgctacctc tatccaataa cgctcgactc cattgcgagc atcctcaaat attccaccat
    26161 ttgctagaat gactgctctg ctagcaggat tattcacact acaggtcacc agagctttct
    26221 tgatgttctt ttccttagca acttgcaagc cctgacggag agtctctttt gcataaccct
    26281 tgcctctttc agatggacga atggagtagc caatgtggcc agcataattc agtaacccct
    26341 cattcagtct caatcgcaga ttcaaaaatc ctagagcaca acctgattca ccaaacaata
    26401 cgaactgtat cgatggaacg cgattttcag gtagccatat tcccatttct ttattacggt
    26461 taccttctag ccactcctcg taagaaaaat cctcaacatc ccaaaatcct ccatcatggg
    26521 ctgattggct cttttcaaac tctgtcatca tatctaaaac agctttctta tccgctaatc
    26581 ttggtctgcg taattccatc cctacctccc actatgagaa aagcgagagc tggctctcac
    26641 ttttattttt tcttgttctt gtttaaaaat tgttctctga agctaagcaa gcgttctttc
    26701 ttaccagctc cacctttaga gtgcttctcg tgataacggg tcacttgtgc gcgcccctta
    26761 tcgtctagtt gatattttcc catttcattt ctttctaatt tgttacttga tgcccagcta
    26821 ttttaatcgt tgaaccattc atatgtttga cacgcgcagc gatttccttg tgacgcccgt
    26881 taaccattgg tctcgcttga ggattgccaa gatagccaca agtccgttta acaacgtcta
    26941 ctgttttagg atcgctattg ccacagtttg gacaagcaaa ccctctctca gttggttcaa
    27001 aatccccttc aaagtcacac ttgtagcaac ggtcaatcgg agtattggtg cctagatagc
    27061 ctacacggtc ataagcataa tcccagacag cttccaaggc ctttggattt tgctgaagga
    27121 ctggatactc acaataatgg atgaaaccac ctgacgcacc tgcttccgga tagactttct
    27181 caaagtctaa tttttcaaac ggtgttggat ttttacgaac atcgtagtgg aaagaattgg
    27241 tgtagtattc cttgtctgtg atatcaggaa tagagccaaa cttgtctata tctagtcggc
    27301 agaaacggtc tgtcagactt tcggatggtg ttgagtagat agagaaatgg tagccatatt
    27361 ggtctgacca ctcttctaca cggcgtttca tatcgtgaat gatgtctagc gtgaattcct
    27421 tagcatctgg attactttcc cagctgttac caaagaaaac tgtcgctact tcatacaagc
    27481 cgatatagcc cagcgaaacg gtcgcacgac gattcttaaa gagctggtca acactttctt
    27541 ctttacctag acgatggcca aaagcaccgt actgataaag aataggagca ttcgctggtg
    27601 tcgcctcttt agtgcgttcg acacggtaaa caagagcatc ttctgcgata ttcattcgct
    27661 cgttgaagat ttcccagaac ttattcatat caccttcaga ctcaagagca atacgaggca
    27721 gattaaccgt cacaacaccc agattcatgc gacctgaatt gacttctaca ccattttcat
    27781 ccttccaccc ttgaaggaaa gaacggcagc ccataggcac cttgaaagaa cctgtcaaat
    27841 caacaatctt atcataagac aagacgtctg gatacatccg cttggttgca cactctagag
    27901 ccaactgctt gatgtcatag ttgggagttc cttcctctaa gttgaggcct cttttaagcg
    27961 taaagataag tttaggaaag atagccgtac ggtgttctga accaagaccc ttgatgcgaa
    28021 tgtttaaaat agctttttga atttctcgtt caaaacgact ggttcccaga ccaaaaccta
    28081 acgaagtaaa aggtgtttgt ccatttgaag tgaagagagt attgatttca tactcaagag
    28141 attgcatggc atcgtagatg tccttttgcg ctttcttcca agcgtaatct tcctgttttt
    28201 caggcaatac ccactcttct gcatctttga gatgtttttg ataattcttc tctgcataag
    28261 gcgccaaaat ttcatcgata cggtcagctg aacagccacc gtactggcta gaagcaacgt
    28321 tggcaatgat ttgagaaatc tgtgctgtcg cagtctggat agacttggga ctctctacct
    28381 ctgcatttcc aatcttaaaa ccattttcca acataccctt aaaatcaatc aaacagcagt
    28441 tggtcatagg ggtataggga ctgtagtcca aatcgtgata gtggatatcc cccttttggt
    28501 gggcattggc tacgtgctta ggaagcattt gcagtccgat tgatttccca acaatccctg
    28561 ctgtcaaatc acgctgagtg ttaaagacat cactgtcttt attagcgttt tcattgacaa
    28621 ctgtctggtc tttgttgaga agtttatgaa tactaaagtt gatatccgtc gcttttgagc
    28681 gctcaaaatc cctctgtgtc cgataagtaa tatactcctc agccagcgca tattctttgg
    28741 cttcaaggag ttcatgttct acgatatttt gaatttcgta aatcttaatt ccctgtggaa
    28801 agcgactatg aatttctgta ataattcgct cagtcagatc atcgaggcgt ttttcaacca
    28861 ggggtgtcac atccataacc ttgtcagccg ccttgtggag agccttgtca atcttgtcca
    28921 catcaaatac aacacgtctc ccatctcgtt tctcgacgaa gagagttggc aaaattgtaa
    28981 ttttttcttc tagtgcaatc atatgcatgc tcttttctaa aatgttcttt ctaaaaagta
    29041 ttataccact ctaaaaagaa aaatcaatat cttgtgttaa aaatcctaaa atttttaaaa
    29101 atacacaaga tattgatttg gttatttaat tttatagact ttaaactctg agtaatcagt
    29161 ctttacttgt tggtaatttt cttttaagag tgtttccact tcagaccaga ctaccacctt
    29221 atcatttacc acaatcacct taggttgttt ttctttcaag tcattaagta acttattacg
    29281 attttcctca gttgctgtat agtgcaacgg ggacaaaatc gccgatggcg acaagcgctc
    29341 actcttacga taaagagtcg cagtatcatc ccatgcatag atagcatctt ccgtatttgt
    29401 ctcctctttt accaaatcag caagacgatt acgttcttga taaggtactg gataaaggac
    29461 aaacttcatc aaaaaaggaa cagacaaaag atagacaaac ccaaaaacta gcagatatag
    29521 atttcctttg aagaaacgac tccataggct aactggcgtt tctcttcggc ttcttctagc
    29581 actacgcccc ctctgttgac tcttaatatt ggttaccaat aaaagtagga aaacagggaa
    29641 gacgaccatc aaataagaag cgtgcagagg ctcttgtgaa aagaaaagta aaatcaaacc
    29701 taaaattacc acaagacttg caggaaccga aatgacgtat agtttaaagg gtttggattg
    29761 aaagagacct aaaaagatac aaaccacaaa tcccaaacca agggacaaca agccataaaa
    29821 aaacatattc tctaaaattt tagaagtaaa atcaaagcga atactgtcaa taggataacg
    29881 aataccacta atcgcatccc caaaacttcc tgttgcagca ctatagtagg cagttggata
    29941 aaagacaagt gaaaaaccta aagccactgc aagaaactga taaaacccat gcgcaaagcg
    30001 tctatgccca aggttaaaga ccaacaagcc taaactcact acagcaataa acaggaacga
    30061 tgataaggga gcaaagaaaa atccgcctgc caaagctagc ccaatccgta caaatccctt
    30121 atcatggctt ggattgctta ggtaagccgc aactaaacta aaggctgcga ataagaaagg
    30181 aagcgctaaa agagtcgcat agcctccacc aaaagcaaga cctgtaacta gcatgtaaaa
    30241 aatagtcacc agatgtccag cttggtctcc ttgctctgtc aaggtgtccg ctgatctaaa
    30301 aaggaaaaat cctcctgcta ccaaggctaa ccactcaaag atggcaaaga aaaatccgcc
    30361 ctgactcacg taagtcagca aataataaag caaaccttga cttccataat agtcgctgta
    30421 aatcttccct gtctgatgaa gcgcccaacc tgcataaaaa tcctgcactt cttgtgcact
    30481 cattaagtcg agtaatagcg gtactcctag agttatcccc gttacaagcg tactccatag
    30541 taaaattttc accaaaggaa gacgacttga ttcacgatga tgcgattctt gttcgatttg
    30601 gtattctaga ggttcacgat tctccttatg aacttcttct actctaccat acacactcat
    30661 atcgtttctc ctgttcaatt tatctgtctt agtatatcaa aaagtcctag gattgtcagc
    30721 ttgcgatggc tgtttgagtg attttttgca tagtttcaca aaggtttcaa tttcccgaaa
    30781 gcggtgtaaa tgtgtctgtt tgaactcaat catatcattc acttcttcct tagttagcat
    30841 gaattcccct cctctttctt tctattcgta aaagacaaga aaaataggtc tggtttgtat
    30901 cctaagttct agatttctta taagataggg gcgaatagct gggcgatttc ttttacaagc
    30961 ttttgatacc agctcgtttt gatagaatga ggatagactt cctgagaatc tgcaaatata
    31021 tttcgaaaat ctcgggcgat ttcccttata gaaggagttt tatagagtaa gactgcattt
    31081 tcataatggt gtaccaagct ccggtagtcg agattgattg tccccaccac cgcaaaatct
    31141 tcgtctacca acatctgctt actatgaata aaacctggac tatactcata aatccgaaca
    31201 ccagcagaaa gaaggtcggg ataagctcct ctcgtgacta actgaatgaa cttcttatct
    31261 ggtatgtaag gggtgataat tcgaacatcg acccctctca tagctgcatt tttgattgtc
    31321 tctgttaaat cataatctat aatcaaataa ggtgtcgtaa tatagaccga ttccgttgct
    31381 tgattgatta aactctgata aacttttttc cctacctgcg ctcgaaaaat tggcttgggt
    31441 ccacttccgt atggaatggt taaaccgtca ctcgggatag aatgattttc taaatgatat
    31501 tgatcaaaat cactaatttc tcctcgatta atgtaccaag tggtcaaaaa taagcgtgtc
    31561 agggctttta ctgctagtcc gtctaagcga attccactat ccttccaata accaaatctc
    31621 tcgacgtggt taatgtactc atctgccaga ttgaccccac cagtataggc tatctgacca
    31681 tcaacaatca atatttttct atgatctctg ttattataag ccactgtcaa acgaggaata
    31741 actttattga atttatgggc ctcgatgccc agctgacgaa gtcgatgtgc ataatctcct
    31801 gttaaagtag ccatacagcc gatatcatca tagagcatct taacctctac accctgagct
    31861 accttttgct ctagtatatc tagtatgcga ttccacatca aaccttcttc tataatgtaa
    31921 tattccaaga aaataaattt ctcagccttt ttaagatctt ctaccatctt tttccacata
    31981 gcttctccgt taggaaaaaa tgtagaggca gtttgatcat agatgtcagc attggtatcc
    32041 atactcaata aggacttgat gactccataa gctgccttgt cactttcttt taatttctct
    32101 tttagtagct ggctatttgc ttcttggaaa tgcatggagc ctagcttctt cagttgtttg
    32161 atttcttttt ttgacaatcg cctttcacca aacatcagat agagcaaggg gccaaatact
    32221 ggcacaaagg ctactaacaa ccaggttacc ttattctcag gagtcgtatt acggttgact
    32281 atcgaaatga ttgtaatgat actcagtaga atgaggacag taatccataa aatgggagcc
    32341 atgcgtccta aataaagaaa gagaccaaaa accagacaaa gttcaagtag cataatcgaa
    32401 agactaaagc catacttgga catcaataat tgaaatttcc tatatttcat atcccctcct
    32461 tgatagtttg aatgctaaaa acaagtaatt gatactagta taacgcaggt attcggtaga
    32521 aggcaagtat ttatgattat tttctaggta aaagtaaaaa ggctgaaaaa tccagccctt
    32581 tctacttgca tagtcttatt tagttaaaac gatttggtcc gatgggtctc tatccatatc
    32641 atctacgacg atttgattac cgtttacagt gtaaattttg acatcatcgc caataatcat
    32701 gcgttgattt gctgaatcaa atgtaacctg tttgactttc tgatccccgt cagattcgag
    32761 ctcagtccat gtaccagtcg ttccagttac cactaaagtg atacggtctc cgtcatcctg
    32821 accagtataa gtcccatcaa tatcggtcgg ctgagcaaca ggttggtttt gtactggagc
    32881 cgcttgattt tggttacccc ctgcatttgc agtattggta ttctgttgag caggctgttg
    32941 gacctgctgc tgagcaacag gctgttgaac ctgttgagct ctttgtgaac aagctactaa
    33001 gagactaaaa cttgctagag aagcaagaga aagtgtgaat ctttttaatt tcatgatgga
    33061 tttcctttct gctaccaatt tagagaaatt ttctctaacc agcaattccc ctagtataac
    33121 aagttcaaaa aagggggtca atttatctgc tcacggtcca gcaggtagcc ccgtacttct
    33181 gagataaaat agagagaccc tgttacgaac agcaagtctt gagcgtctgc cctttcttcg
    33241 aaactgctga taaattctcg gtaagaggga attacatggt aacctgttac atctgtctcg
    33301 tccaaagacc cttgatagtc aaagccagtc atcttgagtt ccacttgagg taaattttca
    33361 gtcagataac ccaacatccc ttgataatcc ttacgtttca aggatccaaa gaggatttga
    33421 ggtcgataac cttcctgctc tttttctttg ataaactcaa ccaagcgagt caaggcaggg
    33481 aggttatgag caccatccaa ataaatctgt gggcgaatac gctccaagcg accagcccaa
    33541 tgggtctgtt ccaaggcctt tcttacagcc tgttcatcaa cagcttcctt tccttctccc
    33601 ataaaaagaa gaaaagtttg caacgccaag gctgcattct cctgctgata gactccttct
    33661 aagcctatgt tcagctgtga aagatttagt aaagagcttg aaaaatcacc attcagcatt
    33721 aaaaaatctt gacctgcctg ataaaggtta acagctaaag attcggcttt tttctgacag
    33781 acaagcctag cttctggagg caatttcgca atcactgcct tcttaccagc cttgaaaata
    33841 ccagctttct gctctgcaat tgcttctaga ctatcaccca aggtttcttg atggtcaagc
    33901 ccaatggagg tgatgacagc aagctctcca gttaccacat tggtcgtgtc aagtaagcca
    33961 ccaattccca cttctaataa aaccaaatcc acctcttgct ccctaaaata aagaaaagca
    34021 actaaggtca gcaattcaaa aaaggacaac tggtcaggag tttgcagaag cgttttctcc
    34081 atctccttga cctgatcagc caaacggata aagtctgcgt ctgctatagg ttgcccatta
    34141 atgcagattc ggtcattgat agagacgata tgaggggagg taaaggtcgc aacttttttg
    34201 ccatgcccca taaataattc cctcataaaa gcaatggtag atcctttccc attagtccct
    34261 gttacgtgga taatagggta agactgctca ggatttccta acaaatccac cgcttgctgc
    34321 attcggccca aacctgatcg aaaattcaaa ccaatccgac tatggagcca ttcttctact
    34381 tcaaacatac acatctcctt gacaaaagtc caatcaatta tcgcattaaa gtatggttac
    34441 taataaaaac aaggccagga ttttcgtccc gacctcttac ctggttagct aataactagc
    34501 tactatgaat gtgaatatgg gctaaaaaca tccactagat gttccaactc ttctcaattt
    34561 ctaagagttg gggtaaaaat gttcactgga cgttccaact cttccccatt tctgggagtt
    34621 gggctgatac agtctcccag actacctgcg tttctaattt ctagcgcagg gctaaaaacg
    34681 tcccccggac gtttttactc ctccataaag ctgttgaaga cttcttcaat catgttccat
    34741 tcgtcttctg agtcttctgg gattggttgc aattcgcctt ctgttccatc ttcgttttcg
    34801 atgaatgagt aagcttggat ttcaacttgt ccgtcttcgt cttcttctgc gttaactggt
    34861 actagaagaa catagttttt accaaattct tcttttccat caattgtcaa aaggatttca
    34921 aacaaggttt catttccttg ctcatctact agtgtgatta gttcacgttc ttcgtggtcg
    34981 tggttatgat cgtgtgacat agcctctcct ttatattaaa attttctatc taaataattt
    35041 tgtaaaatca gctgagctgc taacttatca atgactttct tgcgcttatt gcgactgata
    35101 tctgcttgtt caatcaacat gcgctcagca gccactgttg tcaagcgttc atcctgatag
    35161 tctactggta aaccaaaaaa ctcttctagc tttgctccgt aggcttgact agcttctacg
    35221 cgcggtccac ttgtattgtt catgttttta ggcaagccca ctacaaatcg ttccaccttg
    35281 taagtatcaa ccaattcctt aacgcggtca aaaccaaatt ggccttgttc ttcatttatc
    35341 tggatgattt caagcccttg agctgtaaaa ccaagcggat cgctaatcgc cacccctacc
    35401 gtttttgaac cgacgtccaa tcccataatt ctcataggtt atagatcgac tccttgtcct
    35461 ttgaggtagt aacgaaccaa ttcctcaacg atttcatcac gctcatactt acggatttga
    35521 tttcgtgcat tattataacg aggaacgtag gcagggtctc cactcaatac gtaacctacg
    35581 atttggttaa ttgggttgta acccttatcg ttcaacgaag cataaacatc tgtcaaagtt
    35641 tcgctaattt cttttttatt ggaatcgtcc aatttaaaac gtactgtttc ttcagtaaat
    35701 cccattctaa caccctcttt ccttagaata gtaccattat agcataattc cttaccttct
    35761 acaattcagg cagtctattt atttggattt tctattgttc tgtcgcgcca tttgccaatc
    35821 tatctgaaat atagttgctt ggttcatttt tcaaaagatt ttccaaacca atattcttca
    35881 gatgttccaa ctgggaagcc ttcttgacat ccagaacttg aaaatcaaaa ctagtcgttg
    35941 tttgaagttc cgttgcgctc aatagttttg tttcaagttt gaaacctgcc aatttacgag
    36001 cttcaatgat agacttatcc ttctcctccg cttcaagaag agctttttga gtttcctcca
    36061 ctccatgttg gtcaatataa gtcttcaact catcagagac tggacgtttt tgttggatag
    36121 ttagactcaa aaaagtcttg tccttgtaag taattgtttg tgtctgctgg ctaccatcat
    36181 ctgacttggg caagaccaaa gtcttagtta caactgtatt cttctcagca ttttcaataa
    36241 ctggcaatgc cgactgaagc gtatcttttt ctgtttttgt agctgatcca gtttcttttt
    36301 tctgtccgca accaaccagg acaaaaagga aagctagact aacaagaact atttttttca
    36361 tttctttctt ctttcttttt gaaattaaaa tagaataaga ctgggaagtg ctcccagcct
    36421 tgatgtttat agagctgcac gcaaacgtgc ttctgcattt tctacattac ggacagagcg
    36481 tggtaggaag gcacgaatat cgtcttcctt gtagccaact tgcagacgtt tttcatctac
    36541 aaggattggg ctctttaaaa ttctcggtgt ttccataatc agattgagaa cttcattgac
    36601 actcaaatct tcaatatcca ctccaagggc tttggcatag cgatttttag acgaaacgat
    36661 gctggctatt ccgttatctg ttttggttag aatatccagt aattcttctc tcgtaattcc
    36721 ttctttacca aggttttgtt ctttataact taactggtgg gcattgagcc aggtttttgc
    36781 ttttttacag ctagtacaac ttgagactgt ataaatttta atcatgtacc tacccctttc
    36841 gctacatgtt actatcagtt tagtc
//
LOCUS       DAVDZK010000020        36645 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVDZK010000020 DAVDZK010000000
VERSION     DAVDZK010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.021"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            243..900
                     /locus_tag="VUX16_001166"
                     /pseudo
     CDS             243..900
                     /locus_tag="VUX16_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
     gene            890..1213
                     /locus_tag="VUX16_001167"
     CDS             890..1213
                     /locus_tag="VUX16_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET8124136.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPCILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLAF"
     gene            1317..2147
                     /locus_tag="VUX16_001168"
     CDS             1317..2147
                     /locus_tag="VUX16_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET8124137.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2301..3155
                     /locus_tag="VUX16_001169"
     CDS             2301..3155
                     /locus_tag="VUX16_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET8124138.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKSLFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3255..4628
                     /locus_tag="VUX16_001170"
     CDS             3255..4628
                     /locus_tag="VUX16_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET8124139.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQRHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4621..5682
                     /locus_tag="VUX16_001171"
     CDS             4621..5682
                     /locus_tag="VUX16_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET8124140.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5684..6376
                     /locus_tag="VUX16_001172"
     CDS             5684..6376
                     /locus_tag="VUX16_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124141.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6405..6974)
                     /locus_tag="VUX16_001173"
     CDS             complement(6405..6974)
                     /locus_tag="VUX16_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET8124142.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7109..7723
                     /locus_tag="VUX16_001174"
     CDS             7109..7723
                     /locus_tag="VUX16_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET8124143.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7725..9371
                     /locus_tag="VUX16_001175"
     CDS             7725..9371
                     /locus_tag="VUX16_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET8124144.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRHTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDAFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9383..10669
                     /locus_tag="VUX16_001176"
     CDS             9383..10669
                     /locus_tag="VUX16_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET8124145.1"
                     /translation="MYKVLIVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEDLEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDGAGFVSYLGDKENWWIGLSKEK
                     QGSFTTPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKALFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTVHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10721..11254
                     /locus_tag="VUX16_001177"
     CDS             10721..11254
                     /locus_tag="VUX16_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124146.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11332..11802
                     /gene="nrdI"
                     /locus_tag="VUX16_001178"
     CDS             11332..11802
                     /gene="nrdI"
                     /locus_tag="VUX16_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET8124147.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12095..13357)
                     /locus_tag="VUX16_001179"
     CDS             complement(12095..13357)
                     /locus_tag="VUX16_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET8124148.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIIIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13667..14125)
                     /locus_tag="VUX16_001180"
     CDS             complement(13667..14125)
                     /locus_tag="VUX16_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET8124149.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14122..14562)
                     /locus_tag="VUX16_001181"
     CDS             complement(14122..14562)
                     /locus_tag="VUX16_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET8124150.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14995..15861
                     /locus_tag="VUX16_001182"
     CDS             14995..15861
                     /locus_tag="VUX16_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8124151.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            16199..16756
                     /locus_tag="VUX16_001183"
     CDS             16199..16756
                     /locus_tag="VUX16_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HET8124152.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            16977..18083
                     /locus_tag="VUX16_001184"
     CDS             16977..18083
                     /locus_tag="VUX16_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HET8124153.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            18059..19450
                     /locus_tag="VUX16_001185"
     CDS             18059..19450
                     /locus_tag="VUX16_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124154.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            19447..20625
                     /locus_tag="VUX16_001186"
     CDS             19447..20625
                     /locus_tag="VUX16_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET8124155.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            21050..21283
                     /locus_tag="VUX16_001187"
     CDS             21050..21283
                     /locus_tag="VUX16_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET8124156.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            21566..23515
                     /gene="mutL"
                     /locus_tag="VUX16_001188"
     CDS             21566..23515
                     /gene="mutL"
                     /locus_tag="VUX16_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET8124157.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(23840..24307)
                     /locus_tag="VUX16_001189"
     CDS             complement(23840..24307)
                     /locus_tag="VUX16_001189"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET8124158.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWIPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(24308..25513)
                     /locus_tag="VUX16_001190"
     CDS             complement(24308..25513)
                     /locus_tag="VUX16_001190"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET8124159.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMIENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIEKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQILKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANAYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(25533..26168)
                     /gene="ribE"
                     /locus_tag="VUX16_001191"
     CDS             complement(25533..26168)
                     /gene="ribE"
                     /locus_tag="VUX16_001191"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET8124160.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTWEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(26153..27253)
                     /gene="ribD"
                     /locus_tag="VUX16_001192"
     CDS             complement(26153..27253)
                     /gene="ribD"
                     /locus_tag="VUX16_001192"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET8124161.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCKILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPIGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(27386..27500)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            27657..28250
                     /gene="ruvA"
                     /locus_tag="VUX16_001193"
     CDS             27657..28250
                     /gene="ruvA"
                     /locus_tag="VUX16_001193"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET8124162.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            28260..28823
                     /locus_tag="VUX16_001194"
     CDS             28260..28823
                     /locus_tag="VUX16_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET8124163.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            28820..29497
                     /locus_tag="VUX16_001195"
     CDS             28820..29497
                     /locus_tag="VUX16_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET8124164.1"
                     /translation="MMSNKNKGILIFAILYTVLFMFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(29634..30665)
                     /locus_tag="VUX16_001196"
     CDS             complement(29634..30665)
                     /locus_tag="VUX16_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET8124165.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLRLNPIFLPHS
                     LKGLDFIKDHPEARAENLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(30920..31603)
                     /locus_tag="VUX16_001197"
     CDS             complement(30920..31603)
                     /locus_tag="VUX16_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET8124166.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(31615..32559)
                     /locus_tag="VUX16_001198"
     CDS             complement(31615..32559)
                     /locus_tag="VUX16_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET8124167.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            32691..35522
                     /gene="uvrA"
                     /locus_tag="VUX16_001199"
     CDS             32691..35522
                     /gene="uvrA"
                     /locus_tag="VUX16_001199"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET8124168.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMTAFGVDMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVVTNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGDQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINNILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            35515..36576
                     /locus_tag="VUX16_001200"
     CDS             35515..36576
                     /locus_tag="VUX16_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET8124169.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIVGIVKDMGLTRIGFEDEISVSYY
                     HRMQATFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACFISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMTLTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT        10932 a         6589 c         7842 g        11282 t
ORIGIN      
        1 aatagtccat gctgtggctg gattcttttc agcctactta tactcttcga aactctcttc
       61 aaaccacgtc agcttcacct tgccgtaggt atggttactg acttcgtcag ttctatccac
      121 aacctcaaaa cagtgttttg agctgactac gtcagttcta tctgcttttc attgagtatt
      181 attaagacaa tatgaggaga aagatgaaag aaaaaggatt ttaggagggg gcgcaggcag
      241 ccatgccaac ggctcttggc tatgtcagta tcggcctggc ctgtggaatt atcggtgcgc
      301 cctatgtgac acctgttgag atgggcttga tgagtctctt tgtttatgct gggagtgccc
      361 agtttgccat gttggcactg attgcggttc aagctcctgt ggcagctatt gctatgacgg
      421 tttttctaat caatttgcgt ctctttttgt tgagtttaca cgcatcgact tatttccgtc
      481 ataccagtct ttggtacaat atcggtatgt ctagtatctt gacagatgag acctatggcg
      541 ttttgatggg tgaattggcc catacagaca aggtaaatcc gatgtggatg cacggaaaca
      601 atcttaacag ctatgtggct tggtttgtgg ggacagtagt cggaacggct ctgggtggcc
      661 tgctaccaaa tccagaaatc tttggcttgg attttgcccc tggttgggat gtttattggt
      721 atttttgctt cgcaattcca gatgatgcaa agacggattc ctgtccgcaa tctgctcatt
      781 atcctagcag ttgttgcggt gtccttcttt ttgctcttga cagtggtgtc tcagtcacta
      841 gctgttctgt ttgcgacgct acttggttgt agcatggggg tggttttaga tggtcagtaa
      901 gtatctttta ttagcagtta ttttctctgg cttggtgact tggattcccc gtatgattcc
      961 ctgcatctta gtcaagtata agggcttgcc tgcaatcgtt gagcgttttt tgaagttctt
     1021 gcccgtttcc attatctttg ccttgattct ttcaagcgta gtgacaggta aggttgggag
     1081 ccttcctcaa attaaatggc tagacttctt agccgtcttt ccaacagctt gggtagcctt
     1141 tcgctaccgc aatctagtcg gaacagttct ctttggagta gtcttgattg ccatcttgcg
     1201 tttggccttt taaatcaact ataaaaaaaa cttatcacag agatagatat catataatgg
     1261 cgtaaatgct ctttttctgt taagattata aggtattcta ttttggagga aatgacatga
     1321 aaaaaatcgt taaatactca tctcttgcag cccttgctct tgttgctgca ggtgtgcttg
     1381 cggcttgctc aggtggtgct aagaaagaag gagaagcagc tagcaagaaa gaaatcatcg
     1441 ttgcaaccaa tggatcacca aagccattta tctatgaaga aaatggcgaa ttgactggtt
     1501 atgagattga agtcgttcgc gctatcttta aagattctga caaatataat gtcaagtttg
     1561 aaaagacaga atggtcaggt gtctttgctg gtcttgatgc tgaccgttac aatatggctg
     1621 tcaacaatct tagctacact aaagaacgtg cggagaaata cctctatgcc gcaccaattg
     1681 cccaaaatcc taatgtcctt gtagtgaaga aagatgactc tagtatcaag tctctcgatg
     1741 atatcggtgg aaaatcgacg gaagtcgttc aagccactac atcagctaag cagttagaag
     1801 catacaacgc tgaacacacg gacaacccaa ctatccttaa ctatactaag gcagatttcc
     1861 aacaaatcat ggtacgtttg agcgatggac aatttgacta caagattttt gataaaatcg
     1921 gtgttgaaac agtgatcaag aaccaaggtt tggacaactt gaaagttatc gaacttccaa
     1981 gcgaccaaca accgtacgtt tacccacttc ttgctcaggg tcaagatgag ttgaaatcat
     2041 ttgtagacaa acgcattaaa gaactctaca aagacggaac gcttgaaaaa ttgtctaaac
     2101 aattcttcgg agacacttac ctaccggcag aagctgatat taaataattt cttgaaatca
     2161 tccattctga gtaagatggg tggtttctca gtttttaggg atatagtttt aaactatata
     2221 tctgactatc taataacaat ttgtgaaatc aaacaaattg tgagatacta gtacggtatt
     2281 atttttaagg agaaagaatc atgaaaatca aaaaatggct tggcctagca gcccttgcta
     2341 cagtcgcagg tttggctctt gcagcttgcg gaaactcaga aaagaaagca gacaatgcaa
     2401 caactatcaa aatcgcaact gttaaccgta gcggttctga agaaaaacgt tgggacaaaa
     2461 tccaagaatt ggttaaaaaa gacggaatta ccttggaatt tacagagttc acagactact
     2521 cacaaccaaa caaagcaact gctgatggcg aagtagattt gaacgctttc caacactata
     2581 acttcttgaa caactggaac aaagaaaacg gaaaagacct tgtagcgatt gcagatactt
     2641 acatctctcc aatccgcctt tactcaggtt tgaatggaag tgccaacaag tacactaaag
     2701 tagaagacat cccagcaaac ggagaaatcg ctgtaccgaa tgacgctaca aacgaaagcc
     2761 gtgcgcttta tttgcttcaa tcagctggct tgattaaatt ggatgtttct ggaactgctc
     2821 ttgcaacagt tgccaacatc aaagaaaatc caaagaactt gaaaatcact gaattggacg
     2881 ctagccaaac agctcgttca ttgtcatcag ttgacgctgc cgttgtaaac aataccttcg
     2941 ttacagaagc aaaattggac tacaagaaat cacttttcaa agaacaagct gatgaaaact
     3001 caaaacaatg gtacaacatc attgttgcaa aaaaagattg ggaaacatca cctaaggctg
     3061 atgctatcaa gaaagtaatc gcagcttacc acacagatga cgtgaaaaaa gttatcgaag
     3121 aatcatcaga tggtttggat caaccagttt ggtaataaga aacagggagg tgggagagag
     3181 aattccacct cttgcttttg tatagagcat ggagtgtaaa gaagactatt cgttcataga
     3241 aaggtagaga gaatatggtt tttcctagcg aacaagaaca gattgaaaaa tttgaaaagg
     3301 atcatgtagt ccaacattat tttgaggttt tgcgtacctt gatttctaag aaatcagtct
     3361 ttgcccagca ggttggactc aaggaagtcg caaattatct gggtgagatt ttcaagcgtg
     3421 ttggagctga agtggagatt gatgagagct atacagcgcc ctttgtcatg gcacatttca
     3481 agagttcgcg tccagatgcc aagaccttga ttttctataa ccactatgac actgtgccag
     3541 cggatgggga tcaggtctgg acagaggatc cttttacgct ttcggtccgc aatggcttca
     3601 tgtatgggcg tggggttgat gacgacaagg gtcatatcac agctcgcttg agtgctttga
     3661 gaaaatatat gcagcgccat gatgatttac ctgtcaatat cagctttatc atggagggag
     3721 cggaggaatc ggcttcaaca gacctagata agtatttgga aaagcatgca gacaaactcc
     3781 gtggggcgga tttgttggtc tgggaacaag ggaccaaaaa tgccttggaa caactggaaa
     3841 tttctggtgg caataagggg attgtgacct ttgatgccaa ggtaaaaagc gctgatgtgg
     3901 atatccactc gagttatggt ggcgttgtgg aatcagctcc ttggtatctc ctccaagcct
     3961 tacagtctct tcgtgctgcg gatggccgta tcttggttga aggcttgtac gaagaagtac
     4021 aagagcccaa tgaacgagaa atggccttgc tagaaactta tggtcaacga aacccagagg
     4081 aagttagtcg gatttatgga ttggagttgc ctctcttaca ggaggatcgg atggcctttc
     4141 taaaacgttt ctttttcgag ccagcgctta atatcgaagg aatccagtct ggttatcaag
     4201 gtcagggtgt taagactatt ttacctgcag aagccagtgc caagctagag gttcgtctgg
     4261 ttccgggcct agaaccgcat gatgttctgg aaaaaattcg gaaacagcta gacaaaaatg
     4321 gctttgataa ggtagaatta tactatacct tgggagagat gagctatcga agcgatatga
     4381 gcgcaccagc cattctcaat gtgatcgagt tggctaagaa attctatcca cagggcgttt
     4441 cagtcttgcc gacgacagcg gggacagggc ctatgcatac ggtctttgat gccctagagg
     4501 tgccaatggt ggccttcggt ctaggaaatg ccaatagtcg agatcacggt ggagatgaaa
     4561 acgtgcgaat cgccgattac tacacccata ttgaattagt agaggagctg attagaagct
     4621 atgagtagag atattatcaa gttagatcag atcgatgtga cttttcacca aaagaagaga
     4681 accatcacag cggttaagga tgtgaccatt cacatccaag aaggggatat ctacggaatc
     4741 gttggatatt ctggagcagg gaaatcaacc cttgtacggg tgattaatct cttgcaaaaa
     4801 ccatctgcag ggaaaattac cattgacgac gatgtgattt ttgatggtaa ggtcaccttg
     4861 acggcagagc agttgcgtcg taaacgtcaa gatatcggga tgattttcca gcattttaac
     4921 ctgatgagcc aaaagacagc agaggagaat gtagcctttg cccttaaaca ctctggactc
     4981 agcaaggaag aaaagaaggc taaagtagct aagttgttgg acttggttgg tttggcagat
     5041 cgtgctgaaa actacccttc acaactatct ggagggcaaa aacagcgtgt ggcaattgcg
     5101 cgtgccttgg ccaatgatcc aaaaatcttg atttcagacg agtcaacttc tgcccttgac
     5161 cctaagacaa ccaagcagat tttggccttg ttgcaagatt tgaaccaaaa attaggattg
     5221 acagttgtct tgattacgca tgaaatgcag attgtcaaag acattgccaa ccgtgtggcg
     5281 gttatgcagg atgggcattt gattgaagag ggaagtgtcc ttgaaatctt ctcaaaccct
     5341 aaacaacctt tgactcaaga ctttatctca acagccacag gtattgacga agccatggtc
     5401 aaaatcgaga agcaagaaat cgtggaacac ttgtctgaaa acagtctctt ggtgcaactc
     5461 aagtacgctg gagcttcaac agacgagcca cttttgaatg aattgtacaa gcattaccaa
     5521 gtaatggcta atattctcta tgggaatatc gaaattctcg atggtactcc tgttggagaa
     5581 ttggtggtgg tcttgtcagg tgaaaaagca gcgttggcag gtgcccaaga agccattcgt
     5641 caagcaggtg tacaactaaa agtattgaag ggagtacagt aagatggaat cattgattca
     5701 aacctattta ccaaatgtct ataaaatggg ttgggctggt caggcaggct ggggaacggc
     5761 tatctactta actctttata tgacagttct ttccttcatt atcggaggct tcttggggct
     5821 agtggcaggt ctctttctcg tcttgacagc gccaggtggt gtcttggaga ataaagtcgt
     5881 attctggatt ttagacaaaa ttacctcaat ttttcgtgcg attcccttta tcatcctctt
     5941 ggcaatcttg tcaccacttt ctcacttgat tgttaaaaca agtatcgggc caaatgcagc
     6001 ccttgtccca ctttcttttg cagtctttgc cttctttgcc cgtcaggtgc aggttgtctt
     6061 ggctgaattg gatggcggtg tcattgaggc ggctcaagcg agcggagcga ctttctggga
     6121 catcgtgggt gtttacctat cagaaggtct tccagatttg atccgtgtga cgactgtgac
     6181 cttgatttcc cttgttgggg aaacagctat ggccggtgcg gttggagctg gtggtatcgg
     6241 taacgtagcc atcgcttatg gatttaaccg ctacaatcac gatgtgacca tcttggcaac
     6301 cattattatc attttgatta tctttgcaat ccaattcttg ggagatttct tgactaagaa
     6361 attgagtcat aaataaaaag agccgcgtgg ctctttttaa ctgatcagat tttctgtgca
     6421 aattttttac tcaaggcttg tccaatcaag gcacccacta gggctccgat gacaatactt
     6481 gcgataaata gaaggacagt tccagggttt ggagcgacca tgatacggtc gatatattct
     6541 tgggattttc ctcttgccag aagagtagcc atataggctt tgggcgcaat ccacataagc
     6601 aagattggtc ctgttgtact aaaggcgaaa ataatgaaag aaaggaagtt ctttgttttg
     6661 tccttgtatt ttcctaaatg agctacttca tctgctagga ggccacagat aattccagga
     6721 aggaaggaac cagcaccgtg tttagttccc aagaaaaaga gggcaatgac aaggccgata
     6781 gtggtaatgg ctccaaagcg cggaactttt gcgactagga tcatatagac gctaccgccg
     6841 acaagggcag taaaggcagg cgcataaaac atgtttccag tttggtcaaa gagattgccc
     6901 aaaaggacac caatccccat gcagaggaag taaagaactg caaaaagcag tgtagttaag
     6961 atagatttct tcatgaattg tctcctgata attttttcac aattctcatt gtaccacggt
     7021 ttggtgggat tgtaaatgga tactagaagt ttttgaaaac gcttgaaata tgatataatg
     7081 gtttcatagt tatttttagg ggaatatcat gggtagattt ttagactttg tctttaatcg
     7141 tttcttttta gggatgattg cgacagcctt cttttggcta ttaactttag caggagggat
     7201 tatccttggt ctagcgccgg ctagtgccac cttgatgagc ttatatgcag aacatggtta
     7261 tagctttcgg gaatacagtt tgaaggaggc ttggtctctt tacaagcaaa attttgtctc
     7321 aagcaacctg attttctata gctttttagg tgtgggtcta gttttgacct atggtttgta
     7381 tctcttggtg caattgcctc atcagaccat tgttcatttg attgcgaccc ttttgaatgt
     7441 cctagtagtt gccctgatct ttttggctta tacagtatct ttaaaattac aagtttattt
     7501 tgccttgtcc tatcgaaata gtctcaaatt atccttgatt ggcatcttta tgagtctagc
     7561 agctgtggcc aagattctcc ttgggactgt gctacttgta gcaattggtt attatatgcc
     7621 tgccctgcta ttttttgtag gaattgggat gtggcatttc tttatcagtg atatgttgga
     7681 acctgtctat gaaatcatcc atgaaaaatt ggcgacaaaa tagaatgaag cagttttggc
     7741 tacatacgct tctaagaacc tatagttcag tgatgatcat tatcattgcg agttttgcaa
     7801 tcttactctc ttacgctgac tgggattcac gtgaaaagga agcccagaga gtagcccagc
     7861 gtgtaactgc tagaacagtg agtgaaattg aatattacca tagagagtca acccagatag
     7921 ctcaggcttt agttgaaaac caagctcgta ttgagggaat ctataaatac tttagtctta
     7981 gcatgccaga ctatttttac tggcaattag agcggaaagc ttcgccttat atatcagtct
     8041 ctctgtatga aaatgttgat gacctctatg ttcgaaatga ttttgtaact ggagtggcca
     8101 ttgcttttca agattacaag gaagtctatg tttctactaa agacaaacgt agtggagaaa
     8161 aaatcagggc tgaggatttc aaaccagcag gaaatagttt tgccattccg gtgtcagatc
     8221 cagtgtcaga tcaagattta ggagtgattt acatctcctt ggatcctgct gttttatacc
     8281 atgccattga taatactaga ggtcatactc cgatggcagt aacagtgacc tcaccttttg
     8341 atacggagat ttttcatatt ggtgagacag ttgataagga gagtgaaaat tggctcgttg
     8401 gcttaacatc tcatggctat caggttcagg tggcagttcc taaaaacttt gttttacaag
     8461 gaacagtgac tagctctgct ttgattgtgg gtttgagcct tctctttatt gtcattcttt
     8521 atctgacttt gaggcatact tttgctaatt accaaaagca ggtagtggat ttagtagaat
     8581 ccattcaagt cattgctcaa ggcgaagagg ggcgtcggat tgacatttcc gaaaaagatc
     8641 aggaattact cctaatcgcg gagacgacca atgatatgtt ggatcgattg gaaaagaata
     8701 tccatgatat ttaccagtta gagcttagtc aaaaagatgc caatatgcga gccttgcagg
     8761 cgcaaatcaa tcctcatttt atgtataata cgctggagtt cttgcgcatg tatgcagtta
     8821 tgcagagtca agatgagttg gcagatatca tttatgaatt cagtagtctc ttgcgtaaca
     8881 atatttccga cgaaagagag acccttctca aacaggaatt agaattttgc cgtaaataca
     8941 gctatctctg catggttcgc tatcccaagt ccattgccta tggtttcaag atagatccag
     9001 agttagagaa tatgaagatt cccaagttta ccttgcaacc gctggtagaa aactatttcg
     9061 cgcatggtgt tgaccacagg aggacagata atgtgattag catcaaggct cttaaacagg
     9121 atgcttttgt ggaaattttg gtggtcgata atggtagagg aatgtcggct gaaaagttgg
     9181 caaatatccg agaaaaatta agtcagagat attttgaaca ccaagccagc tacagtgatc
     9241 aaaggcagtc tatcgggatt gtcaatgtac acgagcgttt tgtgctctat tttggagacc
     9301 gctatgccat tacgatagag tctgcagagc aagccggtgt tcagtatcgt attacaattc
     9361 aagatgagta gaaagggaga aaatgtataa agtattaata gtagatgatg agtacatggt
     9421 gacagaaggt ctgaagcgtt tgattccctt tgataagtgg gacatggagg ttgtcgcaac
     9481 agccagtcat gccgatgaag atctagaata tgttcaggaa aatcctgtcg atgtcatcat
     9541 ttccgatgtc aatatgccag acaaaacagg gcttgatatg attcgggaga tgaaagagat
     9601 cttaccagat gctgcctata tcctgctctc aggttatcag gagtttgatt atgtaaaaag
     9661 agcaatgaac cttagtgtgg tggactattt ggtcaagcct gttgataagg tagagctggg
     9721 aaatctgctg gagaagattg caggtcagct cggcgagaga gggaagaaaa gtcagactct
     9781 tagtcaagaa ttagacgggg ctggatttgt tagttattta ggggataagg agaattggtg
     9841 gataggtcta tccaaggaaa aacaaggttc cttcaccact ccctactatg tcttgggtca
     9901 agactggcag attttcattt ctgaccaacc cctagatggt ttagtcgtta caccttttga
     9961 agctccttat caagaacact ttgaacgctg gaagctgaat gctgagaaag ccctctttta
    10021 cggctctgta aatctgcagc agtctgagag tctctttgcc tattacgaac cgatttatag
    10081 ggttatcatt cagggaaatc tcaatcaaat cgtagaagag ttaaatcttt tggagaaggt
    10141 agttcttgaa aatacacctc gtgttccgat taccaaacag ctttttattc agtttgtcat
    10201 ggatgttttc catttatttg aacatctcaa agctgatgac ctgacagaca tcgtcaaaac
    10261 ggttcatgct attcaatcct tcgatgaatt ggttccttat atcaaggaaa ctctgaccag
    10321 ctttttcggt caataccgta tgaatgaaaa tgtggtcagt gtgctggaag tcattggtcg
    10381 tgattaccaa aaagagcttt ccctcaagga tatcagtaag gctctcttta tcaatcctgt
    10441 ctatctaggg cagttgatta agcgtgaaac cgattcgact tttgcagagt tactaaacaa
    10501 acaacgtatt aaggctgccc aacaactttt gctttcaact agtgacagca tcgaagatat
    10561 ttgttatgct gttggttaca gtaaccttgg atatttctat aaagttttcc gaaaattgtg
    10621 cggaaaatcg ccaaaagcct accgaaaaca ggtagaaact atactataag atttgtattc
    10681 ctttacaaaa tgtgctataa tattatcagg aggttctatc atgaaaaaga aaccaattta
    10741 tctatgggtc ttgctaatct tgtctgccct tatttcagtt ccgtctctgt ttggaattgt
    10801 gagtcccttg cctagtaaag aagcccttcg tgctgctcag aaacaagttg caggggtcaa
    10861 tgctcagcaa ttagaagacc agcttaatta tacctataga gtagcagaag catctcattc
    10921 tatttttaat gttgctttga ttgtgctatc tactatttta gtggtcgtag cgattgtctt
    10981 ccttgttcgt aaaaatttgc aatatgcaaa ctatacttac gttggctatg ttttgttagc
    11041 tattattggt tcgatttatg gctatgttgg tttacaagac gctgtgcagt tggttcaaga
    11101 tgagagcatg cgtttgacag tgagtattgg ttcaaaagct gttagcattt tctatatcgt
    11161 catcaatgtt ctcttcctag cccttgtctt ctataagatg tggcgacaac agaaagcctt
    11221 ggcagaagaa gaggaaacag aagagcttgc ctaagtattg acaaaaaaga actatcaaga
    11281 tacaatcttg gtagttgttt tttgattata gataaaatca tggaggtaca tatgaagaca
    11341 atttctttag tttatattag tttgagtggc aacactgaaa gttttgtgac gcgcttgaaa
    11401 gactatctct tgtcccagta caaagggatt gaggttcaaa agattcatat caaggatttg
    11461 gtcaaggaag gcaaaaattt ctacgaaatg gaccatccct atgttgcttt tttgccgacc
    11521 tatctcgaag gtgggaatgg cgtggataac ggagatgttg agattttgac gacaccggtg
    11581 ggagatttta ttgcctatgg taacaatgct agtaagtgtt ttggtgtggt tgggtcagga
    11641 aatcgtaact ttaataacca atactgccta acagccaagc aatacagtca acgctttggc
    11701 tttcctgtat tggctgactt tgaaatgcga ggcatgctgg aagatatcaa acatgtcgca
    11761 gctattatcg cagatttgta tgagttggaa aaggagaatt aatactcaat gaaaatcaaa
    11821 gagcaaacta ggaagctagt cgcaggttgc tcaaagcaca gctttgaggt tgcagataga
    11881 gctgacgtgg tttgaagaga ttctcgaata gtataaagtt cttataagag gtggttgaag
    11941 ttgttcaact gttttttgag tataaacagt ctttaagaac gtaaaaaagc ataagttcag
    12001 gtcttcaaaa ccttgttctt atgcttttta tcatagaaat atttgctgaa ttttctcttg
    12061 aaatgaaacc ttatcttcat ctcgcgcttg tcccttaccc tgcttttccg attgcgagtg
    12121 cgtagataaa gaagatggcg aagccaaaga ggaaaatcaa tcccgcaatg gcaaggtgtt
    12181 tgagccaaga aggaagattt ttgttttcac gtgttaccaa ggcgtaattc aaaagagcaa
    12241 agaaaggtgt tgtcaggaaa gagccaatca tggcaaagcg gagcatggtt gaaacctgac
    12301 cagcgaagaa cttgataatg atgataccga tgatagcagt gatggtcatc cagatgttca
    12361 aagatttacg attatcctct ttttgactga ttagcagtcg gagagattcc tgattaacgc
    12421 gagaatagcc atcgataaca gttataactg ttccaaagat acagaggaag gcaataaagg
    12481 taatcaagta acgggaccat tcgccaagaa cagaggcata catgcccacg aattgagaga
    12541 tgtatttggc tgaagcagct tcaaccgcct gccctgtagg atactgaatc agtgctccca
    12601 gtgccacaaa gaagacggct aggatagctg ttccaatata accagtgtta aagtcaaaca
    12661 gagcgtcttc tgtgttaaag ttgacggtct ttctcttttc agctgaccaa agtgaattga
    12721 tggctgaaat ttcaatagga gccggcatcc atcctaggag ggagacgatg aagggcagag
    12781 ctgccatttg ccaaggtgtc ttctcgacaa aatcagaact gtattctgga tgcttgaccg
    12841 ccgcaatgat aactgcaaga acagtcgcaa tggttaaggc agacataatc catttgacca
    12901 tgccgtctaa aagtttgtag cctccaaaga gtagcatagc ccaaatgatt gcaacgagaa
    12961 tgagggacca ctgagtaatg ctaagtccaa tcattgggaa ggcactggcg atgatagctg
    13021 agcacagaat ggcaacacca gccgtgttga ccatagccga aaagacattg aggataaaga
    13081 aaatccagag atagagtttt cctttttcgg cataaccttc aaccaaagtc tttccagtat
    13141 cagctgtgta ttcagcacca aaacggaaaa atggatattt aaagacattg gctaagatga
    13201 ccaagagaag tagagaccaa ccgtaagaac cgccagcttg agttgaggat acaatgtggg
    13261 aacctccaac agcggcagtt gccattagga ttccaggtcc cattgctttt agcttgcttg
    13321 cccaggttga ttgatttaag gaaatagctt gcgacatgat aaatactcct ttttgaattt
    13381 tcagaataat ctgtatatgt aatctatatt ctacaaaaaa ttttggaaaa atgcaagagt
    13441 attttgaaaa aagatagaaa atttacaaag aaaatctgaa ataactgtta tgatatagag
    13501 gattgaaact agaatagtac acctctgctt ctaaaacatt gttagaaatc gatttgactg
    13561 tcctgatcga tttatcctgt tcttatttca tttcactata gtaaggtgca gcaggataaa
    13621 gaaaaaccga gaagtttctt tctcggattt gcttattatg aggttcctat tttctatgct
    13681 ccaagagttg attgatgtga tctacttttt tagcctctct tttatagaga atagcccaga
    13741 tgatgagata gacaatcgca aactcgataa tgagctggag gtagaaaatc cagtggaaag
    13801 ggaaccaacc agcaagagtt gctagtggga caaagccagc cagcataagg aagaaatgag
    13861 tcagagtggc acgaagcatg ctccagtcac ggctaaataa gcggttgcca aagttgaaga
    13921 gcataccgat ggttgcccag ataagtgtgc agtagagcaa gaccagggca ccgtgaacct
    13981 gatgctgatc catcacttgg ccgatgagag agtagggatt tagtggtgcg taggtatttg
    14041 gtgcataaat gagtgaaaag aggatagaga ggatgaggcc gataagaaca ccggtagctg
    14101 catcgtgaaa tacttgtttt ttcatagttc taatttctcc ttgatggttt ttagataacg
    14161 gcgtgaagag taggtgaagc tttcgttttt caagaaaatt tctaccagac cgtttggcgt
    14221 gagcttgagg tgagagatgg aatcgatatt gatgatttct gattgggaaa tttggataaa
    14281 attggttggc aagagtttaa gaacctgata gagtcgcaaa tcaatgctgt aggtctgact
    14341 cgcggtttct gctagaacct tccgattctc gatatagaag cgctgaatct tgccaatctc
    14401 aactagatag acctgatcat cgatttttcc tttgattttt tctctttggt ccagattttc
    14461 tgcgaactcg atgactttct ggactttttc ggtttcttga ggtgcttgga caatcagctt
    14521 ttcctcctcg taagtctcac taatctgtag ttctactttc atagttttct ctccttttca
    14581 gttatacaag gttgtgatca cttcctgtat atccttatta aacactattt tatagcccat
    14641 ggcaaggaac cttgtctatg tggagggatt gggctcctat gtggtggagc ttttctgttc
    14701 tttctgaaat atggtataat agcactaatc aatttctagg aaaatagata cggaaagggg
    14761 ctgaaagaac taggggaaca gttggaatta gaaagtgata ggtatgaaaa gtggcgttga
    14821 agctgaataa gtttataaag cgtttgaatg aagaaatgga aagtaaataa gttgacgatg
    14881 aattacaaaa tagattttat ctacaatttg tatctttcaa atcattgatt tgaattttag
    14941 atttaatcat gttacaatta aaactgaaat caaatagaag aggaaaatgc aaacgtgggc
    15001 acactattag caacaagatt aaaaaataga cggaaagaat taaaaatgtc tcagcgagaa
    15061 ctagctgaag gtatctgtaa acaggggcaa atcagtcgat tagagagcgg agagtttacc
    15121 cctggagcgg atttcctgaa tgcccttgct aagaagttaa aagtcagtat ggattatttt
    15181 tttgatgagc aggttgtaga gaaagttgag gagttatcag aatttaagaa attagcacag
    15241 acatttatta caaatcgcaa ttatgagtct ttgaaatata tatatgaatt ggagaatgta
    15301 aaagctcacc gcctatcttt agcagataaa atctacatgg aatggataaa atctctgata
    15361 gatttttatt tttacggaca gaaagaagat gcgattgtac gattagaggg ggtattatca
    15421 cagttaagtg tatctgattt gaactatctc caagtttcaa acaccctatt caatttttat
    15481 tatgatattg gagatttagg tcgtttcaat aaaattcgtg aaaaactaga gtatcaagta
    15541 aatcacctca atttgagtac aatcgaagag ttagaactat ctattaagtt taactacaac
    15601 gtttgtcgtt atctatggtt acagaaaaat attgaagaag ctattactaa aattacagct
    15661 actataaaac aatgtaaggc ttacagaacg aattatcttt tggctgattt gtacttattg
    15721 atgggaaatg taagtgaaaa tttttcttct aaaagttcgg tgaaagaata ttttgagacg
    15781 gcatattttc tatacaaact tgaggagaac atgtcaatga ctctgaaagt tgagcattac
    15841 attgcagata taacagaata atgaatacgg tgttcaagtg agcatcgttt ttcaaaccta
    15901 gttcagatac aaaaaagtat caaacaaaaa aaaaataaaa aaacattata aaaacaattg
    15961 acaagctaat tttgaagtga taaaataaat gcaagaaaac aaaaggagag gtatatgaga
    16021 agtttgttta agaaaatagt tgctgtatta gttattggct taattctgtt aggaattgcg
    16081 agaacacctc aagttcataa gatggctaga gggattgatc ctggtcctgc gaattttatt
    16141 tagaaatcaa tttctactaa ttgagtacta attgagtatt aatgggtaaa aagattgtat
    16201 ggataagaaa aatttacttg tattggttac tggttcggta ggtgccagta atgtagatac
    16261 atacttatat tatataaaaa aattctataa tgttaaagtg atactttctg aaaattctaa
    16321 aaaatttata agtaaggaat taattagtta tttttgtgat aaagtttatg atgaaatatt
    16381 tgttgaagag gtagttccgc acgtttttct gccatatgaa tctgacttac ttcttatttt
    16441 accagctacg gcaaatgtga ttggcaaaat tgctaatggt attgctgatg atttagttac
    16501 agcaactgtt ttaaacttta ataaaaaaat aattttttgt cccaatatga actctactat
    16561 gtgggacaat cacatagttc aaagaaatgt atcaattcta aaggagttgg gacatatatt
    16621 tttatttgag tctaaaaaaa catatgaggt aggattgcgt aaagcaatag attcaacatg
    16681 ttcaatgtta caaccacagt cgttagtaaa agaacttatc aaattagaaa atattgtcct
    16741 tgaagaggga cattaaaaac tactgagaat attaaggagg ggaaaaaatg gaaaattcat
    16801 caatcgatgt agatatgctg ttggaagaat tgacacaaga agcaatggtc gttgttgctg
    16861 ttgataagga ctgttaattt aaacttatgg caatatatga aaggttactg gatgttttaa
    16921 attatgcagg cagtagcctt ttattatata caaatggata aagtaaggat aatacaatga
    16981 ttaataaaaa aatacaacaa gttgttttgg aatcattaca gaattttttg aatgggaact
    17041 tcatttcgcc ttgtgtagtc tatgattttg gcttgctgga aactgtactt gatgaattta
    17101 aaaatcaaat tcctgtaaca ttcaattacc aactttttta tgccgttaaa gcaaattcaa
    17161 atgagaagat acttgaattc ttagtagata aaattgatgg agttgatgtg gcgtcattat
    17221 ctgaattaga tgtggctaaa aaatttttcc caccaactca aatttctgtt aatggtcccg
    17281 cattttctta tgaaacttta tataatctga ttaaaaaaca atataaagtt gatattaact
    17341 ttttggaaca tcttcaacaa ttttccccaa aagaatctgt tggaataaga gtaacggagc
    17401 cagatgaact taataatcgt atgagtcgat ttggaataaa tatttgcagt gataattgga
    17461 ctagtaattt acaaaatcct ttaattacac gactgcattt tcattttgga gaaaaagatg
    17521 ataaatttat tgttaagtta gataaaatat tatttaagtt acaagaaatt aataaactta
    17581 gagaggttag agaaataaat cttggaggcg gttttatgaa attatttatg gaaaatcgtt
    17641 tgaaagaatt ttttctatca cttatggaaa tctataaaaa gtacgatatt gatagtactg
    17701 tgactacaat aatagaacca ggtagtgcaa ttacttcatt ttctgcctat atgattacta
    17761 gcccagttaa tgttagtgag gtgaatgagc agcaggttat cacgttagac acatcaatat
    17821 acaccaatac attatggttt gttccgcata ttattacaac gttaaattca agtagtaaag
    17881 agcgttatag tactattctc tatggtaata cctgttatga acatgacaag tataaaatga
    17941 aagtttcgct tccaaggtta actcaaaata gcagtatagt gttttttcct gtaggagctt
    18001 atataaaaag caatcattca aatttacatc gtaatgattt tatgcgggag gtatatttgt
    18061 ggacaaaaaa cttgacatat tagataaagt taaggaatat ttaggaaata aaactactca
    18121 aattctggat aatcaatata aagaattttt gaaacttaat gatataaggc gagcgtttgg
    18181 tatttcagaa aaagtattaa acaattcttt taattttacg agtaaagaat ttaatgattt
    18241 aattaataac gaaaattatt tattcgaata tgcatgtaga attagagagg aatggagaaa
    18301 aaaatgcttt aatcattctt atcgttttct atgctcacct ataattacag atgattttct
    18361 taacacgaag acattgagaa gtagccaaat tgaatataaa tatgagcgat atttatcgaa
    18421 aagttcgata ggcgatagag cggttgatgg ctttgtttcc ttcaatactt taacagctaa
    18481 tggtatgtct gctattaaac tatgtcttga gatattaaac tctattttct tcaagaagaa
    18541 gattgattta ttatattcaa ccggatatta tgaaacaaga tttttattaa ataatcttgc
    18601 taaatcaggt attagttgct atgaggtaag taattgtgaa ttggataaag ataaatttta
    18661 taatgtattc atgatggaac ccaatcgagc cgatttaaca ttacaaaaaa ctgatttcaa
    18721 gatagtagaa tattttgtta agtataaaaa taattcaata aaagtcgtta ttttagatat
    18781 ttcatatcaa ggttctaatt ttaaattagt agaattttta gagaaattta aatttgcgaa
    18841 tgtaattatt tttgtggtac gatctttgat aaaattagat caaatgggat tagaattgac
    18901 aaatggggga ataatagaag tgtttattcc taatcatttg agaaagttga aaaattttat
    18961 tgaagaggaa ttcaataaat ttagaaattc tcacggagct aatctaagcc tctatgaata
    19021 ctgtttgctt gataattctt taactttaaa aaatgattgg aactattctg atttagttat
    19081 gaaatttacg agtaattttt atgctgatat aaaagacttg ttcatggaaa attctgatat
    19141 tgaaatcatc catgaagagg gagtaccttt tgtattttta gatttaatag gtgaaggtaa
    19201 aaaagaatat gaaatgtttt ttcaatggtt aaacttcttt tacaaacagc ttggaatcac
    19261 attgtatgct agaaatagtt ttgggtttcg gaatctaaca gtagagtatt ttggaattat
    19321 tgggacagaa agatatatat ttaagatttg tccaggtgtt tataaagggt taagttatta
    19381 tttgatgaaa tttttattaa aatctttttc aaatgaatat ttaaaaacta ctgatgaggt
    19441 taatagatga aaaatttgat aaagttgcta ataattagat tgattgttaa cttagcagac
    19501 agtgtatttt atatagtagc attgtggcac gttagcaata attattcttc gagcatgttc
    19561 ttaggaatat ttattgcagt aaattatcta ccggatttgt tactaatctt ttttggacca
    19621 gttattgaca gagtaaatcc gcaaaaaatt cttataatat caattttggt tcaattagca
    19681 gtggctgtaa tatttttatt attattaaac caaatatcat tttgggtgat aatgagtcta
    19741 gtgtttattt cagtaatggc tagctccata agttacgtga tagaagatgt gttgattcct
    19801 caagtggtag aatatgataa gattgtattt gcaaattctc tttttagtat ttcgtataaa
    19861 gtattagatt ctatttttaa ttcattcgca tcatttttac aggtggcagt aggatttatt
    19921 ttattggtta agatagatat aggcatattt ttacttgctc tatttatatt attgttgtta
    19981 aaatttagaa ctagcaatgc gaatatagaa aacttctctt tcaaatatta caagagagaa
    20041 gtgttgcaag gtacaaagtt tattttaaat aataaattat tatttaaaac cagtatttct
    20101 ttaacgctta taaacttttt ttattcattt cagacagtag ttgtaccgat tttttctatt
    20161 cgatattttg atggtccgat tttttatggt atttttttaa ctattgctgg tttgggtggt
    20221 atattgggaa atatgctagc gccaatcgta ataaaatatt taaaatcgaa tcaaattgtt
    20281 ggtgtatttc tttttttgaa cggctcaagt tggttagtag caattgttat aaaagactat
    20341 actttatcac ttattttatt tttcgtttgt tttatgtcta aaggagtctt caatattatt
    20401 tttaattcgt tgtaccaaca aatacctcca catcaacttc ttggtagggt aaatactacc
    20461 attgattcta ttatttcttt tggaatgcca attggtagtt tagttgcagg aacgcttatt
    20521 gatttgaata ttgaattagt gttaattgct attagcatac cttatttttt gttttcttat
    20581 attttttata cggataatgg attgaaagaa tttagtatat attagaaatg tttatgttca
    20641 ttcaaaagca taatgactat aactgaaaaa gaaaagtgat atctttaagg ttgttcttct
    20701 tggtggtgag attcgtgaga caacccaagc ttttgtcgga aagattacca atgctttgat
    20761 ggataggatg tactttagca agatgttttt agtggtaacg gtatcgtgga tggacgtgta
    20821 ataacctctt ctttcgagga gtattttact aaaaaactag ccttggagcg ttccccagaa
    20881 acggacttac tcattgactc ttcaaagatt tggggagaag attttgcttc atctgttcct
    20941 tgaaaaaagt cacagcagtc atcacagacg atagtactga acaaaactat gaagagttag
    21001 aaatttatac gcaggtgatt gtataaagga tctggaaata gataagaagt tgattagtat
    21061 tgacctaggt ggtacaaata ttaagattac tgttctttca aatgacggtg agattgaaac
    21121 tttgtggagt attacaacag atacaagtga gaaaggttct caaattatat cggacatcat
    21181 cagttctatt aaaaataaat tgaccgaacg gaatattcct gatagcgacc ttcttggaat
    21241 cggtatggga agttgctcat catactttcc ttgtaaatca taggggctat aaactctccg
    21301 tctacttgtc ctgcaacaat tgaagtctgc tcaaaacgcc gtccgctaat cttttcatag
    21361 actttctccc ttttaggagc ctagctttct agtttgttct ttgattttta ttgagtatac
    21421 cactatttta ctccctctgg caagggactt tgtctatgtg gagggattgg gctcctatgt
    21481 ggtggagctt ttctgttctt tctgaaatat ggtataatag cactaatcaa tttctaggaa
    21541 aatagataca gaaaggggct gaaagatgtc tcatattatt gaattgccag agatgctggc
    21601 aaaccaaatc gcggctggag aggtcattga acgtcctgcc agtgtggtca aagagttggt
    21661 agaaaatgcc attgacgcgg gctctagtca gattatcatt gagattgagg aagctggtct
    21721 caagaaggtt caaatcacgg ataacggtca tggaattgcc cacgatgagg tggagttggc
    21781 cctgcgtcgc catgcgacca gtaagataaa aaatcaagca gatctctttc ggattcggac
    21841 gcttggtttt cgtggtgaag ccttgccttc tattgcgtct gttagtgtct tgactctgtt
    21901 aacggcggtg gatggtgcta gtcatggaac caagttagtc gcgcgtgggg gtgaagttga
    21961 ggaagtcatc ccagcgacta gtcctgtggg aaccaaggtt tgtgtggagg atctcttttt
    22021 caacacgcct gcccgtctca agtatatgaa gagccagcaa gcggagttgt ctcatatcat
    22081 tgatattgtc aaccgtctgg gcttggccca tcctgagatt tcttttagct tgattagtga
    22141 tggcaaggaa atgacgcgga cagcagggac tggtcaactg cgccaagcaa tcgcaggaat
    22201 ttacggtttg gtcagtgcca agaagatgat tgaaattgag aactctgacc tagatttcga
    22261 aatttcaggt tttgtgtcct tgcctgagtt gactcgggct aaccgcaatt atatcagcct
    22321 cttcatcaat ggccgttata ttaagaactt cctgctcaat cgtgctattt tggatggttt
    22381 tggaagcaag cttatggttg gacgttttcc actggctgtc attcacatcc atatcgaccc
    22441 ttatctagcg gatgtcaatg tgcatccaac taagcaagag gtgcggattt ccaaggaaaa
    22501 agaactgatg actctggttt cagaagctat tgcaaatagt ctcaaggaac aaaccttgat
    22561 tccagatgcc ttggaaaatc ttgccaaatc gaccgtgcgc aatcgtgaga aggtggagca
    22621 aactattctc ccactcaaag aaaatacgct ctactatgag aaaactgagc cgtcaagacc
    22681 tagtcaaact gaagtagctg attatcaggt agaattgact gatgaagggc aggatttgac
    22741 cctgtttgcc aaggaaacct tggaccgatt gaccaagcca gcaaaactgc attttgcaga
    22801 gagaaagcct gctaactacg accagctaga ccatccagag ttagatcttg ctagcatcga
    22861 taaggcttat gacaaactgg agcgagaaga agcatccagc ttcccagagt tggagttttt
    22921 cggacaaatg cacgggactt atctctttgc ccaagggcga gatggacttt acatcataga
    22981 tcagcacgct gctcaggaac gggtcaagta cgaggagtac cgtgaaagca ttggcaatgt
    23041 tgaccagagc cagcagcaac tcctagtgcc ctatatcttt gaatttcctg cggatgatgc
    23101 cctgcgtctc aaggaaagaa tgcctctctt agaggaagtg ggcgtctttc tagcagagta
    23161 cggagaaaat caatttattc tacgtgaaca tcctatttgg atggcagaag aagagattga
    23221 atcaggcatc tatgagatgt gcgacatgct ccttttgacc aaggaagttt ctatcaagaa
    23281 ataccgagca gagttggcta tcatgatgtc ttgcaagcga tctatcaagg ccaatcatcg
    23341 tattgatgat cattcagcta gacaactcct ctatcagctt tctcaatgtg acaatcccta
    23401 taactgtcct cacggacgtc ctgttttggt gcattttacc aagtcggata tggaaaagat
    23461 gttccgacgt attcaggaaa atcacaccag tctccgtgag ttggggaaat attaaaagta
    23521 taaaaaagtc tgggaaaaat gttcaaaatc agaaaaacgc ataaaatcag gtgttcaaaa
    23581 accttgattt tatgcgtttt atcatagaaa tatttacttc atgttttcct aattcttttc
    23641 gaaactcttt ttaaaccacg tcagttttat cagtaatctt aaaacagtgt tttgagctaa
    23701 ttttgccagt tttgtctgta acatcgaagt tgtgtttgac cactctgcga ctggtttcct
    23761 agtttgctct atgattttca cagagtatta aattgcgatt ttgccaagtt tctttattcg
    23821 tctaaaagta gagtctgttc tatgcgtcta atgtacgaat taggttgacc atttcaatag
    23881 ctccttgtgc acactcagaa cccttatttc ctgctttagt gccagctcgt tctatggctt
    23941 gttcaattgt atctgtcgtt agcacaccaa acataacagg aatttcgcta tttaaactga
    24001 tttgggcgat tcccttagat acctcgctac atacataatc ataatgactt gtattccctc
    24061 taatgacagc tcctaagcag ataattgcat catatttttt actttttgcc atttttgatg
    24121 caatcagtgg tatttcaaaa gctcctggaa tccaggctac ctcgatatct ttctcgttta
    24181 cattctctct tttgagatta tctagtgctc cagataataa ttttgaagtt ataaattcat
    24241 taaatctcgc tacaacaata cctattttaa tattgtttgc tactaaatta ccttcataag
    24301 tgttcattta tttttcctcc atatttaaaa tgtgacccat tcgatttttc tttgtttcta
    24361 aataaaaact atcgtaagca ttggcttcta tttcgattga tattctactg gaaatggtaa
    24421 ttccatattt ttctaactgt tcaaccttgt caggattatt tgtcagtaaa tgaagtgact
    24481 gaagtcccag atctttaagt atttgtgctc caatatggta ttctcttaaa tcaccttcaa
    24541 agcctaatgc aagattggca tcaagcgtat ccatgccttg atcttgtaaa tgataggctt
    24601 ttaatttatt gataagtcca attcctcgtc cctcctgtcg caagtaaagt aagacacccg
    24661 aaccattctc aacaatcatt ttcatagctt tatcgaattg ctgtccacaa tcgcaacgta
    24721 aagagcctaa aacatctcct gttaaacatt cggagtggac ccgacataat acattggctt
    24781 catcctctat atttcccata ataagagcaa gatgatgttc cccatttagt ttatctatat
    24841 agctaattgc tttgaaatta ccgtatctag taggcatatt gacagttgaa actcgttcta
    24901 ccagctgatc atatactttt ctatattctt gtaattcttt gatggtaatt agtggaatgt
    24961 tgtgtttctt cgagaactga attaaatcat ctgttctcat cattttgcca tcatgattca
    25021 ttatttcaca acataggcca cactctttta gtccagctaa ttttaataaa tcaacagttg
    25081 cttctgtgtg tccatttctt tctagaacac cacctttttt ttcaattaaa ggaaacatgt
    25141 gtcctggcct gcgaaaatca gagggtgtta tatcttcagc tacacacata cgtgcggtca
    25201 gtcctctttc ctcggcagaa atacctgtgg tcgtttcttt ataatcaatt gaaactgtaa
    25261 aagcagtctt atgattatct gtattgtttt caatcatagg tgaaagcatt aattgattag
    25321 ctaaactttc gctcataggc atacaaatta atcctttggc ataagtagcc ataaaattaa
    25381 cattttctgt tgtagctgct tgtgcagaac aaattaagtc tccttcattt tctctatcct
    25441 tatcgtctat aacaagaaca agtcgtccct tctgcaatgc ttctaatgct tcttgtattt
    25501 ttcgatattc cattgactga ttatcctttc tgctaaaatc cattttgata taatagttcc
    25561 ttagatattt ctgattttgg agaattatcc atcagttttt gcacatattt acctaagata
    25621 tcattttcaa gatttactgt actcccgact tgtttactct taagaatggt ttgttcccag
    25681 gtatgaggga taacagatac tgaaaagttt actttggaga ctttagcgac agtcagacta
    25741 atgccgtcaa ttgtaataga tcctttttca actattaaat ctaaaatttc tttttgtgtg
    25801 ttgatttgat accatacagc attatcatct ttttttattg acgagatttt tcctgtacca
    25861 tcaatgtgtc ctgtaacgac gtgaccccca agtcgaccgt tgacagataa ggctctttct
    25921 agattcacct cacttccatg ttttaataga gtaagagctg ttcgactcca tgtttcattc
    25981 attacatcaa ctgtaaagga ttgatgattg aaatgagtaa ctgtaagaca gataccattt
    26041 actgctatac tatcacctaa atggatatcc gttaatattt ttgaggcttt aattgatagt
    26101 ttacaattac gagagtcttt ctgtattctt tcaacttttc cgatttcttc aattattcct
    26161 gtgaacatgg ataaatcact tcactttcta tgagatagtc atttcctatt tgagaaaaag
    26221 cataaggttt caatctaata gcgtcatttg gcaaagaaat gccttcacct ccgataggaa
    26281 acttggcact gcctccaaaa atttttggtg caatatatat tttcagctca tcaacaattt
    26341 gttgttccaa agcactccaa ttcattagac tgcccccttc tagaactagg ctatcaatct
    26401 gcatgtttcc tagatgttgc attaaactcg ataagtctat atgattgcct tttttcttta
    26461 tggaaagtat tttacagcca tgattttgat atagcttcat tttatttttg tcttcagagg
    26521 aagtggcaat gtaagtttta atatcatttg ctgtttttac gattttagag gtaagaggag
    26581 ttcgtaaatg tgtatcgcat atgatacgga taggattttt cccttcctcc aatctacatg
    26641 tcagcaaagg atcgtcttga ataacagtgt tgactcccac cataattgca ctaacatggt
    26701 gtcgtaactg atgcacatgc tttcttgctt cttcttcagt aatccatttg gattgatttg
    26761 ttttagtggc tatttttcca tccattgaca ttgcatattt cataaaaaca tagggtacat
    26821 gctgggtaat atactttcta aaacttttta ttaagttaag acactcattt tctaaaattc
    26881 caacagtaac ttgaagatta ttttcctcaa gtatctttac tccttttcca gatacaatag
    26941 gattacagtc taggcttcca atgactactc ttgtaatacc actatcgatt atagcatcta
    27001 tacagggagg tgttttcccg aagtgacaac agggttcaag tgttacataa agcgtcgctc
    27061 cgacagggga ttctctacag tttttaagag catttctctc agcatgtggg ccaccaaaaa
    27121 actcatgata accttgtccg atgatgtgat tatcttttac aataactgcg ccgaccatag
    27181 gattggggtt gacgtaacca gccccttttt gtgccagttt tattgctaat ttcatatatt
    27241 ttgaatcgct catctcacta cctccaaaaa atataccttg aataggggac tactcaaggc
    27301 atacaaaaga aaacttatgc gattaacaaa aatgctctga aatgacaagt aatcatttca
    27361 gagcacgcaa aaagcacaaa tatactttta tcttctttca tccagactat actgtcggct
    27421 ttggaatttc accaaatcat gcctttcggc tcgtgggcta taccaccggt agggaattgc
    27481 accctgccct gaagatagtt attcaattac agatgattat agtacttaat tttgaatatg
    27541 tcaacagata aataccgatt gtttttgata tactgtattt gtgataatcg attctcgctc
    27601 ctcggataaa gaaaatatga tatactagat aaacgaaata agagagaagg aatactatgt
    27661 acgcatattt aaaaggaatc attaccaaaa ttactgccaa atacattgtt cttgaaacca
    27721 atggtattgg ttatatcctg catgtggcca atccttatgc ctattcaggt caggttaatc
    27781 aggaggctca gatttatgtg catcaggttg tgcgtgagga cgcccatttg ctttatggat
    27841 ttcgctcaga ggatgagaaa aagctctttc ttagtctgat ttcggtctct gggattggtc
    27901 ctgtatcagc tcttgctatt atcgctgctg atgacaatgc tggcttggtt caagccattg
    27961 aaaccaagaa catcacctac ttgaccaagt tccctaaaat tggcaagaaa acagcccagc
    28021 agatggtgct ggacttggaa ggcaaggtag tagttgcagg agatggcctt cctgccaagg
    28081 tcgcagtgca agcaagtgct gaaaaccaag aattggaaga agctatggaa gccatgttgg
    28141 ctctgggcta caaggcaaca gagctcaaga aaatcaagaa attctttgaa ggaacgacag
    28201 atacagctga gaactatatc aagtcggccc ttaaaatgtt ggtcaaatag gagcagagaa
    28261 tgacaaaacg ttgttcgtgg gtcaagatga ccaacccact ctacatcgcc tatcatgatg
    28321 aggagtgggg ccagcccctc catgatgacc aagcgttgtt tgagttgttg tgtatggaaa
    28381 cctatcaggc aggcctgtct tgggaaacgg tactcaacaa acgccaagct ttccgagaag
    28441 cctttcatag ctatcaaatt cactcagtcg cagagatgac tgacactgaa ttggaagcca
    28501 tgctggagaa tccagctatc attcgaaata gagccaagat ttttgctaca cgcgctaacg
    28561 cccaagcctt tctacagtta caggcagagt acggctcttt tgatgcctat ctttggtctt
    28621 ttgttgaggg gaaaactgtc gttaacgatg ttcctgatta tcgccaagcc ccagctaaaa
    28681 cacccttatc tgagaaatta gccaaagatc tcaaaaaacg aggcttcaag ttcacaggcc
    28741 cagtcgccgt attgtctttt ctacaggctg cagggctagt tgatgatcac gagaatgatt
    28801 gtgagtggaa aggtcttaaa tgatgtctaa caaaaataag ggaattctga tttttgcgat
    28861 tctctataca gtcctcttta tgtttgatgg cgttaaattg ctggcttctt taatgccatc
    28921 tgccattgca aattatcttg tttatgtagt tttagctcta tatggctcct tcttgttcaa
    28981 ggatagattg atccaacaat ggaaggagat tagaaagact aaaagaaaat tcttctttgg
    29041 cgtcttaaca ggatggctct ttctcattct gatgactgtt gtctttgaat ttgtatcaga
    29101 gatgttgaag cagtttgtgg gactagatgg acaaggtcta aatcagtcta atattcaaag
    29161 tacctttcaa gaacaaccac tactgatagc tgtttttgct tgtgtcattg gacctctggt
    29221 agaagaatta tttttccgtc aggtcttatt gcattacttg caggaacggt tgccaggttt
    29281 actaagcatt attctggtag gacttgtttt tgctctgact catatgcaca gtttggctct
    29341 atcagagtgg attggtgcag ttggttactt aggtggaggc cttgcctttt ctattattta
    29401 tgtgaaagaa aaagagaata tctactatcc cctacttgtt cacatgttaa gcaacagcct
    29461 ctccttaatc attttagcta tcagtatagt aaaatgaaat gagaacagga caaatcgatt
    29521 tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatatact gtaatatgtg
    29581 atgaaaatgc cagtaatgat accgagaaaa aagctgagaa acttttccca gctttatttg
    29641 ttatagtcaa agagaatgac ttgttcctgt gcatctacat gagcatggac cccaaagggt
    29701 acaattgctc ttggagttgc gtggccgaca ttcagattat agacaatcgg gatattgctg
    29761 tcaatgatat ccaatagtgc ctctttatag tcgtcatgga aagtttcatc cataggtttt
    29821 ccgaccaaga gtccattgat gaccgcgaat atgccagtgt cctttaaagt tagcaacatc
    29881 tttttgaagt cttctggctt aggcttttct tcgcttgttt cgagcaagag gattttccct
    29941 tcccagtctg acaagtcagg gaaaagtttg tatttttggc agagctccgt gctatctgcg
    30001 tatcgagagt tgtcaaagat atcgtagagg gattcgaggc aaccaccgag gattttcccc
    30061 tcgaactggg cacttccttg caacaagtca aaacctgtat ttgtatgact gacacgaggt
    30121 gttcccaggg ccgtgggact aaaatcagtt cgttcctcat accaaacgtc actagggcgg
    30181 atttctgaaa ttcttcccgt ctcaatcaat tctttaaagt agtgaaggct ataggctagc
    30241 atttctttgt ctaattcaca aatgtctgct aaaaaggatt gaccataaaa agtcttgatt
    30301 cctaatttat gcaacatgag gtggttcatg gttgtatccg agaagccaag aaaaattttt
    30361 tgtttgataa ccttttggag ttggtcattt tcaaaaagat aaggtagcaa gcgataggta
    30421 tcgtctccac cgatggcaca taggatcatg tcgatgctat catcagaaaa ggcatgaatc
    30481 aaattctctg cacgagcttc aggatggtcc ttgataaagt ctaatccttt taacgaatgg
    30541 ggcaaaaaga tgggattgag tctcagatcc ttgagacgtt ggatacccaa gtccacttcg
    30601 tgtttgacaa aatcctctcc gataatgcca ctagataaac taacaatacc aatagtagaa
    30661 accatatctc atcctcctag aaatagattg agcctatttt atcacaaaat ataagagaaa
    30721 gctatgtggg atttcagaag aatactttta atactcttcg aaaatctctt caaaccacgt
    30781 cagttttatt tgcaacctca aagctgtgct ttgagcaacc tgcagctagc ttcctagttt
    30841 gctctttgat tttcattgag tataactcaa aaaagtaagt gaaaaagcaa ccgcacctgc
    30901 agttgctttt atcgttttct tattcttgat agcgtgttgg tcctgcactt gcactacgga
    30961 tattcaagcg tttcttgaga tagaagcgaa gggctaggag ggctgctcca ataatagcta
    31021 gtggcaatgg atccagtact gggttaaggc tagctggtag gaagcttgtt gcaaagaaga
    31081 caagcaacca aaggaacata gaagctagga taactagtac agatttccag aaaggtggac
    31141 gttgactgcg atccatatct ggtccatagt attggtaaac aaagtagtac atcaagtaga
    31201 aggcaaatcc accaaccagt ccaactaata gaagagtaat caatccatag ccgaaagctt
    31261 gatctgccgc aaagaaggtt gtgagggcgc tgacaagggc aaagaggcta gtgatgaaaa
    31321 gagctgagtc cataatcatc agttttggat catcattttc ttttggatgc tctttttcgt
    31381 actgctcttt gacagtgaag ctatgagccc aatgagttgg tgcgccgtat agggaacggg
    31441 cagttgtacc tttagattgc tcctcaagga tttggggaat gacttcctca aaaatagtct
    31501 ggatttcagc gtctgttttc ccatctttga tgaattgttg ggtagcaatg tggacaaact
    31561 cttggttttt cttagttaat ttttgtagat caatttgaga cataggaact cctcttagaa
    31621 ccatttttta tggatgagat agagagtgag cgagacactc atagcaaagg cgataaagac
    31681 gattaaccag aaggcatttg gctctccgtt tagggggatt tcattatcct taaagttcat
    31741 cccgtaggca gaaaagacca tggttgggat ggacatgacg atggtcacaa gggccaaggt
    31801 tttcatgatg ttgttctggt tgttagaaat gatagaggca aaggtctctg tcatagaatg
    31861 caagacgttt ccataaatat ctgccatctc gatggcctgt tgggtttcaa tcagggtgtc
    31921 ttcaagcagg tcttcgtcct caaggtattt cttgatattg ctggttgaac tggtcaattt
    31981 cttaatcacg cgctcatttg ttttgaggga ggccttgaaa tagacgatag ttttttccaa
    32041 ttccatgagc tcaatcaatt cttcattacg agttgattga tgcagttgac tttcgatttg
    32101 ttcactcttg cggtcgattg aacgaagggc tgttaggtaa agctctgcat tgcgataaag
    32161 aatttgaaag ataaaacgtg aacgcatgaa ggtatagaaa ttacgcaatc gacggttgat
    32221 aaagacatca aggacaggta gtggttccaa acacgtagtg ataatggttt cctcagtgat
    32281 gataatacca agcgggatgg ttacgtagta ggtgcggtta tttctttcct ccgtgaccgg
    32341 cacgtctacg ataatcaggg tatactcgtc ttcaatggta atacgagaca tttcttccgc
    32401 atcgagcggt gctcgaaggt cggcaatatc aatatcgaag gtgttggcga tttcgagtga
    32461 ttcattttga gtcggattga cgagattgat ccaagtaccc ggttcaagcg tatcgatctc
    32521 tttaaattca gttgttgtag agagaaaaac ttgtttcata tcccttatcc tttctcattt
    32581 ttcagatttt ttcacactgt actattatac tacaaaatcg gccttttggg taatagaatc
    32641 tcactttttt tggtataatg gtaagcaata atggactaga aagaacaaag atgcaagata
    32701 aaattgtcat tcatggggcg cgtgcccata atttaaaaaa tattgatgtg gagattccgc
    32761 gagacaagtt ggttgtcgtg actggcttgt caggttcagg gaagtccagt ctggcttttg
    32821 ataccctcta tgcggaggga caacgtcgct atgtagagag tttgtccgcc tacgctcgtc
    32881 agttcttggg aaatatggaa aaaccagatg tagatgccat tgatggtctc agcccagcta
    32941 tttccatcga ccagaaaacg actagtaaaa atcctcgctc gacggtggga acgacgactg
    33001 aaatcaatga ctatctgcgt ctcctctacg cacgtgtggg gacgccttac tgtatcaacg
    33061 gacatggagc tatcaatgct tcttctgtgg agcaaatcgt tgataaggtt ttggagttac
    33121 ctgaacgcca gcgcttgcag atcttggctc ctgtcatccg caagaaaaaa ggccaacata
    33181 agagtgttat cgagaaggtt cagaaagacg ggtatgttcg tgtccgtgtg gatggggaag
    33241 tctatgatgt gaccgaagtg ccagagttgt ctaagagcaa gcaacacaat atcgatgtcg
    33301 tggttgaccg tattgttatc aaggagggca ttcgtagccg tctctttgat tccattgaag
    33361 ctgcccttcg tatcgcagaa ggttatgtga ttatcgacac catggacgat tcggagttgc
    33421 tcttctctga gcattatgcc tgtccagttt gtggatttac tgtcccagag ttagagcctc
    33481 gtctcttctc tttcaatgct ccctttggct cttgtagtga gtgtgacggc ttggggatta
    33541 agctggaggt ggatactgat ttggtagtgc cagatgccag caaaacgcta cgtgaggggg
    33601 ctttggcacc ttggaatcct atctcatcta actactatcc aaatatgcta gagcaggcta
    33661 tgacagcctt tggagtggat atggataagc cctttgagga cttgtcagaa gaagataaga
    33721 acttgattct ctacggctcg gatggcaaag aatttcattt tcactatgag aatgaatttg
    33781 gcggtgtgcg cgatattgac attccttttg agggagtcgt cactaatatc aagcgtcgtt
    33841 accatgagac taacagtgat tacacgcgca ctcagatgcg tctctacatg aatgagctga
    33901 cctgcggaac ctgtcaaggc tatcgtctca atgaccaggc cttgtctgtc cgtgtgggcg
    33961 accagcaagg gccacatatt ggagaaatct cagacctgtc tatcgctgac cacttggact
    34021 tggtgagcca gttaactttg tctgaaaatg aagccatcat tgctcgtccc attctcaagg
    34081 aaatcaagga tcgtttgacc ttccttaata atgtgggtct taactatcta accctgtcac
    34141 gttcagcagg aaccctttca ggtggggaaa gtcagcgcat tcgtttggca acccagattg
    34201 gttccaacct atcaggcgtc ctctatatcc tagacgagcc gtcaatcggt cttcaccaga
    34261 gggacaatga tcgcctgatt gccagtctga aaaagatgcg tgacttgggc aatactctta
    34321 tcgtggtgga acacgacgaa gataccatgc gtgaggctga ttatctgatt gacgttggtc
    34381 ctggtgccgg tgtttttggt ggtgagattg ttgcagcagg tacacctaag caagtggctc
    34441 gcaacagcaa gtctatcaca ggtcagtact tgtcaggcaa acgtgtcatc ccagtaccag
    34501 aagagcgccg tgtcggaaat ggtcgtttta ttgaagtgat aggagcgcgt gagaacaact
    34561 tgcaaaatgt cacggctcgc tttccactag gaaaatttat cgcagtgaca ggtgtgtcgg
    34621 gttcagggaa atcgactcta atcaacaaca ttctcaaaaa agccattgcc cagaagctca
    34681 accgtaattc agacaaacct ggtaagttta agactattac agggattgag catgtcgacc
    34741 gtttgattga tattgaccag agccctatcg gacggacgcc gaggtctaac ccagctacct
    34801 atacaggagt ttttgacgat atacgtgacc tttttgctca gacaaatgaa gccaagattc
    34861 gaggctataa gaaggggcgc ttcagtttca acgtcaaggg aggtcgctgt gaagcttgct
    34921 caggtgacgg gattatcaag attgagatgc acttcttgcc agatgtttat gtggcttgtg
    34981 aagtttgcca cggaacccgc tataacagtg aaaccctaga agttcactac aaggaaaaga
    35041 atatttcgca ggtcttggat atgacggtca acgatgcggt agaatttttc caacacattc
    35101 cgaaaattca acgcaaactc cagaccatca aggatgtagg gctaggctat gtgaccttgg
    35161 gacagccagc taccaccctt tctgggggag aagcccaacg tatgaagtta gctagcgaac
    35221 tccacaaacg ctcgacagga aaatctttct acattctgga tgagccgacg acagggcttc
    35281 atacagagga cattgctcgc ctgctcaagg ttttagctcg ctttgtagac gatggcaata
    35341 cagtcctcgt catcgagcac aatctggatg ttatcaagac ggcagaccat atcattgact
    35401 tgggacctga gggcggtgtc ggtggtggaa ccatcatcgt aacaggaact ccagaagaag
    35461 tagctgccaa cgaagccagc tatacaggac actatttgaa aggaaagtta catcatgaat
    35521 aaacgcgtac aagcatttct agctaaaatg caagaaaaag aactagatgg tatcatcatc
    35581 aacaatctta aaaacgtcta ttatttgact ggtttttggg gctcaaacgg aacagtcttt
    35641 atcagccgtg accgtcaggt cttagtgaca gactctcgct atatcatcgc agctaagcaa
    35701 gaaaccagtg gttttgagat tgtggctgat cgtgatgaat tggctgtcat tgtaggaatt
    35761 gttaaggaca tgggcttgac tcgtatcggt tttgaagatg agatttcagt gtcttattac
    35821 caccgtatgc aggcaacttt tgcaggtttg gacttgcttc cacaaactca gtttgtggaa
    35881 ggtcttcgta tgattaagga tgaggcagag attgcagcga ttcgcaaggc ttgttttatc
    35941 tcagaccaag ctttccgcga tgcgcttgac tttatcaaac caggaaaaac tgaaattgag
    36001 attgccaact tccttgattt ccgcatgcgt gagttgggag catctggctt atcttttgat
    36061 acgatcctag ctagcggtat caattcttct aaaccccatg cccatccaat gcacaaacca
    36121 gtggagttgg gagaagccat taccatggac ttcggctgtc tctatgacca ctatgtcagt
    36181 gatatgaccc ggactatcta tctagggcat gttagcgatg agcaggcaga gatttacaat
    36241 acggttctaa aagctaacca agccttgatt gaccaagcta aggcaggctt aggtttccgt
    36301 gactttgaca aaatccctcg tgatattatc attgaggcag gttatggcga ctactttact
    36361 cacggcattg gccacggtat tggtctggat atccatgagg aaccctactt tagccagact
    36421 tctacagaaa ctattaagac aggtatgacc ttgaccgatg aaccaggtat ctatatcgaa
    36481 ggcaaatatg gcgttcgtat cgaggatgat atcctgatta cagagacagg ttgtgaatta
    36541 ttgaccctag ctccaaaaga gttgatagtc atttagttgt ttgtcaagaa aaaagtacga
    36601 aaatgacgaa aaaagtcaaa aaaaattaaa aataggtcgc aagtc
//
LOCUS       DAVDZK010000021        35720 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVDZK010000021 DAVDZK010000000
VERSION     DAVDZK010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.022"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(<1..2660)
                     /locus_tag="VUX16_001201"
     CDS             complement(<1..2660)
                     /locus_tag="VUX16_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET8124170.1"
                     /translation="MTSDKQNVKVARKTFQSSLKASRIHYRREKKGLKRSLPKRRFII
                     RRAEKAETREQRQTLKQTYQEETDLATDTFTKAISYVSPRWLKVKDIRKYRLPQARHR
                     LTVARKHLAENKMAEKEQAINPKFTYQKEPNQKTPSRFHFQKEKSLDRLQAEKKVNSA
                     KRDVKQLKRAHKAKKASTKFKRGLRYVASDSLDLVAQDDDLEGIRTVKDMSIKGRRYG
                     RFIYQSGKLLVTSGQTGMRFTKTKIAHGKERYQNFKKGKGFTRQKPLKHKRRYHTFLK
                     QARKHSVSGIKGVIQAIKGSLTFFSTIVLNPMTWVVSGLLFFLLLMMSFVVGISGTSL
                     IQQDEGELTKAYTHMTWEDAENTRTNDTGITYYTKIDDVMGFMNLKYQDYALEEVMEN
                     GDKTYQVYLSQLWHDLNGGDSLKAMLELTKEPAYKLSDDDREELKELSKEGTYLALQE
                     LDNPFQGQTEDDTLTMTVRYGYEMIEDKPTLHHHIILEAKENQVIVAPMDGKVSLDGE
                     NLIITSGKGLNKSQLTLFNVHTGRVTDGQKVQAGEMIGQTKDGSGLKVTYQKVDNDSE
                     KLVYVNPAFYFPKVIQLQTTILPTIGQFGGDEFARAKVIYEYLKSQGATNQAIAAILG
                     NWSVESSINPKRAEGDYLSPPVGATDSSWDDEGWLSLNGPAIYNGRYPNILRRGLGLG
                     QWTDTADGSRRHTLLLKYAKRQNQKWYDLDLQLDFMLHGDNPYYTNWLKDFFKNSGSP
                     ASLAQLFLIYWEGNSGDKLLERQTRAAEWYYQIEKGFSQPNGGTAQSDPKALEAVRED
                     LYDNSIPGGGDGMGYAYGQCTWGVAARINQLGLKLKGRTGEKISIINTMGNGQDWVGT
                     AARLGGETGKLPKAGAIISFAGGQYGHVGFV"
     gene            complement(2657..4987)
                     /locus_tag="VUX16_001202"
     CDS             complement(2657..4987)
                     /locus_tag="VUX16_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET8124171.1"
                     /translation="MKPKTSSKHKKTGKPKEKVLPTTANTLRYQGLFPNGLMQVTSDY
                     FSQSYLLGDVNYQTVGLEDKGAIMETYSDLINSLDDKTNFQLTIFNQRVNLDKFRKSV
                     LYPMHEDGYDTYREELNRIMENNLEAGENNFSAIKLISFGKSDQNPKLAYRSLSQIGE
                     YFKSGFSEIDANFTLLNGESRVNHLADMLRGENHLPFTYQDLVRSGQTTKHFIAPTSL
                     SFKHKNYIEIDDRLLQIVYVRDYGMELGDKFLRELMQSDLEVVISLHAKGSAKSEAMT
                     KLRTKKTLMESQKIGEQQKMARSGVYLEKVSQVLESNIDEADELIKTMTQTGDKLFDT
                     LFLIGVFADNADRLKHSLDIIKQVSGSNDLIIDNLSYMQEAAFNSLLPFGKNYLEGVS
                     RSLLTSNIAVNSPWTSVDLQDKGGKFYGINQISSNIITIDRGKLNTPSGLILGTSGAG
                     KGMATKHEIISTKLKEADTDTEIIIVDPENEYSIIGQSFGGESIDIAPDSTTFLNVLD
                     LSDDNMDEDPIKVKSEFLLSWIGKLLDRKMDGREKSLIDRVTRLTYKHFETPSLVEWV
                     FVLSKQPEQEAKDLALDMELYVEGSLDIFSHHTNIKTDSHFLIYNVKKLGDELKQIAL
                     MVIFDQIWNRVVKNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRVRKYGAIPTGI
                     TQNVETLLLDANGRRIIANSEFMILLKQAKNDREELVHLLGLSKELEKYLINPEKGAG
                     LIKAGSTVVPFRNKIPHQTKLFDIMSTDPEKMRTEA"
     gene            complement(4965..5318)
                     /locus_tag="VUX16_001203"
     CDS             complement(4965..5318)
                     /locus_tag="VUX16_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET8124172.1"
                     /translation="MNTRVFKDITKVQHRAWLGFTTRQVIFVLPAIALTILILGLNLF
                     YWQFGDWIVYGLIFTFTIPLMLFGVYRPNDLPFETYLNYRWHYEMTIPNRTLTGQKGI
                     RREKNKPLNETKDFF"
     gene            complement(5508..6359)
                     /locus_tag="VUX16_001204"
     CDS             complement(5508..6359)
                     /locus_tag="VUX16_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HET8124173.1"
                     /translation="MNTLPSAFVFLASEKISSDSLFEGFNVDLESTANLIKSLADYNP
                     TVWSYMSAITKGIMQPLGVAILAVVLVLEFSKMAKKIANSGGAMTFEAIAPMMVSYIM
                     VAVVITNTTVIVEAILAAASHIIEGVAGVVSHGGATYETISGLKGSGIIGKLIVGFFA
                     ILIWLVRLVSVMVVNLLITIRFIQLYLMIPFAPLTIPTFLSDDWRSVGIGYLKNIMVY
                     ALQGVLIFLIISLVPLFESAGKLAVSNGAGVMETLATTFGGLVQAILLIIALVGSQRT
                     ARSILGM"
     gene            complement(6379..6621)
                     /locus_tag="VUX16_001205"
     CDS             complement(6379..6621)
                     /locus_tag="VUX16_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124174.1"
                     /translation="MNQKLTGFVYGVDASSMFAQAMALLQKGMIATGAFLVVMGIINL
                     STNIKDGGPGVRNAILEIVGGVMVGAAGAFITQITI"
     gene            complement(6639..8459)
                     /locus_tag="VUX16_001206"
     CDS             complement(6639..8459)
                     /locus_tag="VUX16_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003086094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET8124175.1"
                     /translation="MASGKKAFIFGVLGLAFGYFCHRLVLLYDSLPNQPSIERFAYLL
                     GEGQNQVLNPLWKGNFTGRSVLGFCFGFVTMGLVYLYVSTGQRVYREGAEYGSARFGN
                     NRERKAFISKNPLNDTILSRNVRLTLLEKKAPQFDRNKNLVVIGGSGSGKTFRFVKPN
                     LIQLNCSNIVVDPKDHLAEKTGKLFLENGYQVKVLDLVNMTNSDGFNPFRYVETENDL
                     NRMLTVYFNNTKGNGSRSDPFWDEASMTLVRAISSYLVDFYNPPGSTKEEADSRRKRG
                     RYPAFSEIGKLIKLLSKGENQDKSVLEVMFESYAKTYGTENFTMRNWADFQNYKDKTL
                     DSVIAVTTAKFALFNIQSVIDLTKRDTLDLKTWGTQKTMVYLVIPDNDTTFRFLSALF
                     FSTVFSTLTRQADVDFRGQLPIHVRSYLDEFANCGEIPDFAEQTSTVRSRNMSLVPIL
                     QNIAQLQGLYKEKEAWKTILGNCDSLLYLGGNDEETFKFMSGLLGKQTIDVRSTSRSY
                     GQTGSGSTSHQKITRDLMTPDEVGNMKRDECLVRIAGVPVFKEKKYFPLKHKNWKYLA
                     DKETDERWWHYHIAPLKHEEESLDLSDHRVRDLSTETTLH"
     gene            complement(8459..8947)
                     /locus_tag="VUX16_001207"
     CDS             complement(8459..8947)
                     /locus_tag="VUX16_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124176.1"
                     /translation="MSSEQQERQALQYAERSTMFTVRVLLKLLEWSARQALAQDSAYK
                     IGVQKLEELLQSPYAIEWLNISKDILDKPIDVEKFKELMESENLPIAISWQGDYLYFY
                     AKDKSLLDKHLDKLLQKLVSNPEKLQGLTLDKTLDEEIAKAKEQIVMSEPSAVKAKEV
                     IL"
     gene            complement(9023..9604)
                     /locus_tag="VUX16_001208"
     CDS             complement(9023..9604)
                     /locus_tag="VUX16_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET8124177.1"
                     /translation="MRRILLAYGAIHVNVLLVSFFLVGVLNEVVLIALQVSFFALVLW
                     VWKCFKIPKRNLSLKERGLWLLVSLGVMVSTALIMSAIFSGYAVNQETLVTVQDQAPM
                     LPFILFLLNASVVEEVFYREVLWGVLSQPVVQFLLTSFLFTLAHHPSSLITWGLYGSL
                     GLVLGLVRLKADCFTSTLVHLSWNGIVFFLSLL"
     gene            complement(9607..9840)
                     /locus_tag="VUX16_001209"
     CDS             complement(9607..9840)
                     /locus_tag="VUX16_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET8124178.1"
                     /translation="MNDRFWENLESIVIERGMSWADLARKMFKGQYVYPSEFKRLYQT
                     FRHYKSHHLMPQVKWVEKVVSVLEIDYEDLFRR"
     gene            complement(9850..10233)
                     /locus_tag="VUX16_001210"
     CDS             complement(9850..10233)
                     /locus_tag="VUX16_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124179.1"
                     /translation="MLEIYLSRNTSRNQNLLSFYDTHGISYTPKEVNDLSREDLLSLF
                     TKSSDCFALLSPSLQRFKGHREMKLSELVTLVLRKPDQNLRLPLVICEDKVYPDMSLE
                     EARTFLPRTHKVVSFREHLFKQLTE"
     gene            complement(10243..10671)
                     /locus_tag="VUX16_001211"
     CDS             complement(10243..10671)
                     /locus_tag="VUX16_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124180.1"
                     /translation="MKLLHTKSIRDCTELEEVIHQAEVERIAETIASLPNYDCEIEVT
                     FEDDYHQEMNVPLAYESNLHRLFEFMETQDLKNGVDSYLAEENHLVFRAFGQHYMANG
                     KDDLLTTRITVKSFGEGRTPIDMSKVFTPLTQKLPKDLSV"
     gene            complement(10652..12010)
                     /gene="dcm"
                     /locus_tag="VUX16_001212"
     CDS             complement(10652..12010)
                     /gene="dcm"
                     /locus_tag="VUX16_001212"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET8124181.1"
                     /translation="MKFLDLFAGIGGFRLGLTRQGHECIGFCEIDKFARKSYKVIYDT
                     EGEIEFHDIRQVTDQDFRQLRGQVDIICGGFPCQAFSLAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLSHDKGETFATILSTLDELGYDIEWQVLNSKDFQVPQNRE
                     RVFIIGHSRRYHPRFLFPLRGENSSAHLERLGNVNPSRKGMNGEVYLATGLSPTLTQN
                     KGEEAKIAIPVLTPDRLEKRQHGRRFKDNQDPMFTLTVQDRHGVVVAGTLPTSFVQTG
                     RVYDQSGLSPTLTTMQGGDKVPKIICREEAPHLKIKEATKLGYAKATVGDSVNLAYPE
                     STKRRGRVGKGISNTLTTSDNMGVVVAALEYRKDKWYEVTGIILDGKLYRLRIRRLTP
                     RECFRLQGFPDWAYERAESVSSKSQLYKQAGNSVTVTVIEAIAREFRKIEEEEGHEII
                     TH"
     gene            complement(12170..12997)
                     /locus_tag="VUX16_001213"
     CDS             complement(12170..12997)
                     /locus_tag="VUX16_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET8124182.1"
                     /translation="MKRITANHYQTSERYYKLPKLLFESERYKDMKLEVKVAYAVLKD
                     RLELSLSKGWIDEEGAIYLVYSNSKLMALLGCSKSKLLTIKKTLREYGLIDEVQQSSS
                     EKGRLANKIYLGELEDDTSPVLKSDGGGVKKTRGQSQKQTGQVLNSAPSETEISETKK
                     NETERNESVIEDEEEKKEVTFGKKQEESLTRKVDHVTKYDVGYIWNLVYERLRQEGLS
                     RVTSEYAMVHFEDRYRYALEHMRFVNTAEAIAEYVFNGVLSEWSKQIRLNEAKKGGW"
     gene            complement(12994..13167)
                     /locus_tag="VUX16_001214"
     CDS             complement(12994..13167)
                     /locus_tag="VUX16_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124183.1"
                     /translation="MQKKEQSSRQVVVGYLMDVMSVDIEEANHLVSGLEHEGLVCFES
                     NGDVTVLVLEGQS"
     gene            complement(13326..13433)
                     /gene="blpN"
                     /locus_tag="VUX16_001215"
                     /pseudo
     CDS             complement(13326..13433)
                     /gene="blpN"
                     /locus_tag="VUX16_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
     gene            complement(13449..13703)
                     /gene="blpM"
                     /locus_tag="VUX16_001216"
     CDS             complement(13449..13703)
                     /gene="blpM"
                     /locus_tag="VUX16_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET8124184.1"
                     /translation="MNTKMMEQFEIMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            13984..16137
                     /gene="blpA"
                     /locus_tag="VUX16_001217"
     CDS             13984..16137
                     /gene="blpA"
                     /locus_tag="VUX16_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HET8124185.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYILNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILKACELAEIRQDIERMPMDYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVFTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            16148..17509
                     /locus_tag="VUX16_001218"
     CDS             16148..17509
                     /locus_tag="VUX16_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET8124186.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSFVATKE
                     ITVTSQGEIAPTSAIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFRNFTKQSHDIELGISKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINKRARLPTGNPHQSILNRY
                     LVAAQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIIHLSSEFEGKNRI
                     PTGTEIAQIFPIITDTREVLITYYVASDYLPLLDKGQTVRLKLEKIGNHCITIIAQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            17566..17721
                     /gene="blpC"
                     /locus_tag="VUX16_001219"
     CDS             17566..17721
                     /gene="blpC"
                     /locus_tag="VUX16_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET8124187.1"
                     /translation="MDKNQNLTSFQELTTTELNQITGGGWWKDLLHRFNVIEQNNTKG
                     FNQPIQL"
     gene            complement(17763..19103)
                     /locus_tag="VUX16_001220"
     CDS             complement(17763..19103)
                     /locus_tag="VUX16_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET8124188.1"
                     /translation="MNIVWILLHTLITNGLEIVIFFKVDGINLTFERIFKAFLLKILL
                     VFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKN
                     KLHERLNQEQTLRYRDMERHSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDSVLKDSSQKLQDNKYDLGRLVNIRDRALKSLLAGKFLKARDKKIIFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASAEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIHTE"
     gene            complement(19117..19855)
                     /locus_tag="VUX16_001221"
                     /pseudo
     CDS             complement(19117..19855)
                     /locus_tag="VUX16_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(19860..20198)
                     /locus_tag="VUX16_001222"
     CDS             complement(19860..20198)
                     /locus_tag="VUX16_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET8124189.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQKRILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            20454..20783
                     /locus_tag="VUX16_001223"
     CDS             20454..20783
                     /locus_tag="VUX16_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET8124190.1"
                     /translation="MTDTDPIKRAQALITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETADNRVLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLSL
                     YGPTIIL"
     gene            complement(20844..21893)
                     /locus_tag="VUX16_001224"
     CDS             complement(20844..21893)
                     /locus_tag="VUX16_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124191.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWIFVQTLFLLLFAPLFLAMGYGLPVFLVYVLLLGVGKYFLFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKVVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSLLAQVFIEQSWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQAVVRGLTSLVLVVELVVGLVTFQEKLALLALLGAGLVL
                     QVLYLPYQVKRQMQD"
     gene            complement(21890..22621)
                     /locus_tag="VUX16_001225"
     CDS             complement(21890..22621)
                     /locus_tag="VUX16_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124192.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYKELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            22689..23099
                     /locus_tag="VUX16_001226"
     CDS             22689..23099
                     /locus_tag="VUX16_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET8124193.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            23109..23396
                     /locus_tag="VUX16_001227"
     CDS             23109..23396
                     /locus_tag="VUX16_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124194.1"
                     /translation="MKLSNLLLFAGATAGSYLVTKNRQTITDEILNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKILEKDIQTRLAVIKEMQGTEDK"
     gene            23557..23796
                     /locus_tag="VUX16_001228"
     CDS             23557..23796
                     /locus_tag="VUX16_001228"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124195.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDKVSSKHCF
                     EVVDRTDEVSNHTHGKPTLTWFEEIFEEYHSPFHN"
     gene            complement(24122..25258)
                     /gene="dnaJ"
                     /locus_tag="VUX16_001229"
     CDS             complement(24122..25258)
                     /gene="dnaJ"
                     /locus_tag="VUX16_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET8124196.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(25602..26006)
                     /locus_tag="VUX16_001230"
     CDS             complement(25602..26006)
                     /locus_tag="VUX16_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HET8124197.1"
                     /translation="MDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARYREI
                     ILAEHDSCIKNDEAVRNFVTSVLLSAFVSALVSAMISLEIQTYKFVIPFIIGVIWTVV
                     VFLMINWNYIANTKKRQKYINISVLIGYLKSK"
     gene            complement(26017..27840)
                     /gene="dnaK"
                     /locus_tag="VUX16_001231"
     CDS             complement(26017..27840)
                     /gene="dnaK"
                     /locus_tag="VUX16_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET8124198.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNSDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVIAGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQETGNAGDDVVDGEFTEK"
     gene            complement(28320..28844)
                     /gene="grpE"
                     /locus_tag="VUX16_001232"
     CDS             complement(28320..28844)
                     /gene="grpE"
                     /locus_tag="VUX16_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET8124199.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(28871..29905)
                     /gene="hrcA"
                     /locus_tag="VUX16_001233"
     CDS             complement(28871..29905)
                     /gene="hrcA"
                     /locus_tag="VUX16_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET8124200.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKAIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVVAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYL
                     YLSSNHYEVH"
     gene            complement(30069..30578)
                     /locus_tag="VUX16_001234"
     CDS             complement(30069..30578)
                     /locus_tag="VUX16_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET8124201.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSCFGLFYFEQ
                     GQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCMSSFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            31186..33519
                     /locus_tag="VUX16_001235"
     CDS             31186..33519
                     /locus_tag="VUX16_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET8124202.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKSGEHITYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKEDSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIGD
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVGEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLDKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            33532..34995
                     /locus_tag="VUX16_001236"
     CDS             33532..34995
                     /locus_tag="VUX16_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET8124203.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERAALNHKIDNVLADILQLLEDK"
     gene            34995..>35720
                     /locus_tag="VUX16_001237"
     CDS             34995..>35720
                     /locus_tag="VUX16_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET8124204.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRI"
BASE COUNT        10777 a         7644 c         6689 g        10610 t
ORIGIN      
        1 acaaacccaa catgcccgta ctgaccaccc gcaaaagaga taatcgctcc tgctttaggt
       61 aactttcctg tctctccacc aagacgtgcc gcagtgccta cccaatcttg accatttccc
      121 atggtattga tgattgagat tttctcacca gttctgcctt tgagtttcaa gcctagttgg
      181 ttgatccgag ctgccactcc ccaagtacat tgaccatagg catagcccat gccatcacca
      241 ccacctggga tagaattatc ataaaggtct tctcgaacag cttcaagtgc ttttggatca
      301 ctttgggcgg ttccaccatt aggttggcta aagcctttct caatttggta ataccactcg
      361 gcggctcttg tttgacgttc taggagctta tcgccactat ttccctccca ataaatgaga
      421 aagagttggg caagactagc tggacttcct gaatttttga agaagtcttt taaccagttg
      481 gtgtaataag gattatctcc gtgcaacatg aaatccagtt gtaagtctaa gtcataccat
      541 ttctgatttt gtcgtttggc atattttaat aagagcgtat gtctgcgtga cccatctgcc
      601 gtatctgtcc actgacctaa tcctaagcca cgtcttagga tatttgggta cctgccatta
      661 tagatagctg gaccattaag ggacaaccat ccctcatcgt cccaagagct atccgttgcc
      721 cccacaggag gcgataagta gtcaccttct gctcgtttag gattgataga ggattctact
      781 gaccagttcc ctaaaatagc cgcaatcgct tgattggtcg caccttggct tttcaaatac
      841 tcatagatga ccttagctct cgcaaactca tcgcccccaa attgaccaat agtcggtaga
      901 atggtcgttt ggagttgaat cacctttgga aaataaaagg ctggattgac ataaaccagt
      961 ttctctgaat cattgtcaac cttttgatag gttactttga gaccagaacc atctttggtt
     1021 tgaccaatca tctctcctgc ttgaaccttt tggccatcgg tcactcgacc tgtatggaca
     1081 ttaaacaagg tcagttgaga cttattgaga cccttacctg acgtgataat aaggttctct
     1141 ccatcaagcg ataccttgcc atccatgggt gccacaatca cttggttctc tttggcttct
     1201 aaaatgatat ggtgatgaag cgttggcttg tcctcaatca tctcatagcc atagcgaacc
     1261 gtcatagtta gcgtatcatc ttcagtttgt ccttgaaaag gattgtccaa ttcttgtagg
     1321 gcaaggtagg taccttcctt acttagttcc ttcaattctt ccctatcgtc atccgagagt
     1381 ttgtaggcag gctccttggt tagctcaagc atagctttta aagaatcccc accgtttaag
     1441 tcatgccaaa gctgactcaa ataaacttga taggtcttat ccccattttc cataacttct
     1501 tctaaagcat aatcttgata cttgaggttc ataaagccca tgacgtcatc aattttcgtg
     1561 tagtaggtaa tgccagtatc gttggttctg gtgttttccg catcttccca cgtcatgtgc
     1621 gtataggctt ttgtcagctc accctcatct tgttggataa ggctggtgcc tgaaattcca
     1681 acgacaaaac tcatcatcaa aagcaagaaa aataagagac ctgacacgac ccaagtcatg
     1741 ggattgagga caattgttga aaagaaggtt agacttccct tgatggcttg aataacccct
     1801 tttattcctg acacactgtg tttcctagct tgtttgagaa aagtgtggta tcgtcttttg
     1861 tgttttaagg gtttctgacg ggtgaagcct ttcccctttt tgaaattctg ataccgttcc
     1921 ttgccatggg cgattttagt cttggtaaaa cgcataccag tctgtccact tgtcacaagc
     1981 aattttcctg actgatagat gaacctccca tagcgtctgc ctttgatact catatccttt
     2041 acggttcgaa ttccttctag gtcatcatct tgagcaacta aatcaagtga gtctgaagcg
     2101 acatagcgta accctcgttt gaatttcgta gaggctttct tagccttatg ggctcttttc
     2161 agttgcttca cgtcacgctt cgctgagttt accttttttt ccgcctgaag gcggtcaaga
     2221 cttttctctt tctggaagtg aaatcgtgaa ggagtctttt ggtttggctc tttctgataa
     2281 gtgaacttag gattgatagc ctgctctttt tctgccatct tgttctctgc caagtgtttt
     2341 ctcgctactg ttaagcgatg tctggcttga ggaaggcgat actttctgat gtccttgacc
     2401 tttagccatc tgggtgacac ataggagata gcttttgtaa aggtatctgt cgctaggtct
     2461 gtctcctctt ggtaggtctg tttcaaggtt tgcctttgtt ctctcgtttc agctttttct
     2521 gcccgtctga tgataaaccg tcgtttagga agtgagcgtt tcagcccctt cttctcccta
     2581 cggtaatgaa tacggctagc ctttaaacta ctctgaaagg ttttacgggc taccttaacg
     2641 ttctgtttgt ccgatgtcat gcttcagtcc tcatcttttc tggatcggtg ctcatgatgt
     2701 caaagagttt ggtttgatgt gggattttat ttctaaaagg aacaaccgtt gaccctgcct
     2761 taatcaatcc agctcccttt tcaggattga tcaaatattt ctccaactct ttggataagc
     2821 ccaaaagatg aaccaactct tctcggtcat tcttagcttg ttttaagaga atcatgaatt
     2881 cgctattagc gataatgcgt ctgccattgg catctaacaa aagagtttcc acgttctgcg
     2941 taatccctgt tggaattgcc ccatacttac ggacacggct ccagagcttg aagaagaaat
     3001 cagaagcgta cttatccagc aacagaagct gcatttcatc aaagtaaatc caagtcttct
     3061 tccctagttt ttgattttta accacacgat tccaaatctg gtcaaagatg accatgaggg
     3121 caatctgctt caattcatcc cctaactttt taacattgta aatgagaaaa tgactatcgg
     3181 ttttgatgtt ggtgtggtgt gagaaaatgt caagtgagcc ttccacatag agttccatat
     3241 caagagccaa atccttggct tcttgttcag gttgtttgga gaggacaaag acccattcta
     3301 ctaaggacgg tgtctcaaaa tgcttatagg tgagccgtgt cacacgatca atcagtgact
     3361 tctcgcgacc atccattttc cggtctaaga gttttccaat ccaagagaga agaaattccg
     3421 acttgacctt gatagggtct tcatccatgt tatcatcaga taggtctaag acgtttaaaa
     3481 aggtagtaga gtcaggcgcg atgtcaatgc tttccccacc aaaggattgg ccgataatac
     3541 tatactcatt ttcagggtcg acaatgatga tttcggtatc agtatctgct tcttttaact
     3601 tggttgagat gatttcatgc ttggttgcca ttcccttacc agcacctgat gttcctaaaa
     3661 taagacctga tggggtattg agtttcccac ggtcaatggt gataatatta cttgaaatct
     3721 gatttatccc atagaatttc ccacccttat cttgtaaatc aacggaagtc catggggaat
     3781 tgacggcaat gtttgaagtc aagagtgacc gagacacacc ttcaagatag ttctttccaa
     3841 aaggtaacaa gctattaaag gcagcttctt gcatgtagga aagattatca ataatgagat
     3901 cattagaacc tgacacttgc ttgataatgt caagtgagtg cttcaaccga tctgcgttat
     3961 ccgcaaagac cccaatcaaa aagagggtgt caaagagctt gtctcctgtt tgcgtcatgg
     4021 ttttaatcag ctcatcagct tcatcgatat tgctttctag gacctgacta accttttcaa
     4081 gatagacacc tgatcgtgcc atcttttgtt gttccccaat tttttgtgat tccatcaagg
     4141 tcttcttggt gcggagcttg gtcatagctt ctgacttggc tgagcctttg gcatgtaaac
     4201 taatgaccac ttccaaatca gactgcatga gttcacgtag gaacttgtcc cccaattcca
     4261 tcccataatc acgaacgtaa acaatctgaa ggagtctatc gtcaatctct atataattct
     4321 tatgtttaaa ggatagactg gttggggcaa taaaatgctt ggtcgtttgt cccgaacgca
     4381 ccaggtcttg ataggtaaag ggcagatgat tttcccctcg caacatatca gccaagtgat
     4441 tcacacggct ttctccattg aggagagtaa agttcgcatc tatttctgaa aaaccactct
     4501 tgaagtattc cccaatttga gaaagagagc gataagccag tttcggattt tggtctgact
     4561 tcccaaacga aataagctta atagctgaaa agttattttc accagcttct aggttattct
     4621 ccatgatacg attgagttct tcacggtaag tatcgtagcc atcctcatgc atgggataca
     4681 agacactctt tctaaacttg tccaagttaa ctctttggtt aaaaatggtt aattggaaat
     4741 tggtcttgtc atccaaactg ttaatcaagt ccgaataagt ttccataatc gctcccttat
     4801 cttcaagtcc taccgtctgg taattaacat ctcctaaaag ataggactgg gaaaaataat
     4861 cagatgtgac ttgcatgaga ccattaggaa aaagtccttg gtaacgaagg gtattggcag
     4921 ttgttggcaa gaccttttct tttggtttac ctgtcttctt atgcttagaa gaagtctttg
     4981 gtttcattga gtggtttgtt tttctcacgg cgtattcctt tctgtccagt tagtgtgcgg
     5041 tttggtatag tcatttcgta atgccatcga taattaagat aagtttcaaa gggcaagtca
     5101 ttaggacgat agaccccaaa taacatgaga ggaatggtaa aagtaaaaat aagtccatag
     5161 acaatccaat ccccaaattg ccaataaaaa aggttcagtc ctaagataag gattgtgagg
     5221 gcaatagctg gcaagacaaa gatgacttgt cgtgtggtaa agcccaacca agccctatgt
     5281 tggactttcg tgatgtcctt aaaaacacgt gtattcataa atagtagctc cttctttgaa
     5341 aaaggactaa gatggaaatc tcagtccagt ttgaacggtt tcatgtcttt gacgcagtag
     5401 acgtctgaac tctctacgct agttcctagc tatgacagtt ctagtcgtcc ttgcggaggt
     5461 aagacgacgc cttcgactgc aaagcagtac cgattcctgt cctactctca catgcctagg
     5521 atgcttcttg cagtccgttg actgcccacc aaggcaatga ttaataaaat agcctggact
     5581 aagccaccaa aggtagtcgc taacgtctcc attactcctg ctccatttga aacagctaat
     5641 ttcccagcag attcaaagag gggcacaagg gagatgatta agaaaattaa gactccttgg
     5701 agggcataga ccatgatgtt tttcaggtag ccaatcccaa cacttcgcca gtcatcacta
     5761 aggaaggttg gaatggttag aggcgcaaaa ggaatcatga gataaagttg gataaagcga
     5821 atggtaatga gaagattcac taccatgaca ctaaccaacc gaaccagcca tatcaaaatg
     5881 gcaaagaagc cgacaatcaa ttttccaata attcctgacc cttttaaccc tgaaatggtc
     5941 tcataagtcg ctcccccatg agaaacgacg ccagccactc cttcaatgat gtgagaagca
     6001 gcggctaaga tggcttcaac aatcacagta gtatttgtaa tgaccacagc caccatgata
     6061 taagagacca tcattggggc aatggcttcg aaggtcatgg ctccacctga gttggcgatt
     6121 ttcttagcca ttttagaaaa ctcaaggact agaacaacag ctaaaatagc cactcccaag
     6181 ggctgcatga ttccctttgt gatggccgac atataagacc atacggttgg gttataatcc
     6241 gcaagggatt tgatcaagtt agcggtcgat tccaagtcta cgttaaagcc ttcaaagagg
     6301 ctatcacttg aaattttctc tgaggctaga aagacaaaag ctgaaggtaa tgtattcatc
     6361 ttgtcatacc tagccctcct aaatggtaat ttgagtgata aaggcaccag cggcacccac
     6421 catgacacca cccacaattt ctaagatggc attgcgaaca ccaggtccac catctttgat
     6481 attggttgaa aggttaataa tgcccatcac gacaagaaag gctcctgtcg caatcattcc
     6541 cttttgtaaa agtgccatgg cttgggcaaa catggaactt gcatccacgc cataaacaaa
     6601 gcctgttaat ttttggttca tacgattcct catttctatt agtgtagtgt ggtttctgtg
     6661 cttaaatccc taaccctgtg gtctgataag tccaaacttt cctcctcatg tttcaagggg
     6721 gcaatgtggt aatgccacca acgctcatct gtctccttat ctgcgagata tttccagttc
     6781 ttgtgtttca aagggaaata tttcttctcc ttaaaaacag gaacccctgc aattctcacc
     6841 aagcactcat ctcgtttcat gtttccgact tcatcagggg tcatgagatc cctcgtaatt
     6901 ttttgatggg aggtagaacc agaccctgtt tgcccatacg accgactggt acttcttaca
     6961 tcaatggttt gtttgcctaa gagaccactc atgaacttga aggtctcttc atcattgcca
     7021 ccaagataaa gcaaactatc acagttccct agaatcgttt tccaagcctc cttctcctta
     7081 taaagtcctt gaagttgggc aatgttttga aggataggaa cgagactcat gtttctggag
     7141 cgaaccgttg aggtttgttc cgcaaagtct gggatttcac cacaattcgc aaactcatcc
     7201 aagtaacttc taacgtggat aggcagttgt cccctaaagt ccacgtcagc ttgtctggtt
     7261 aaggttgaaa agacggtgga gaaaaaaagt gctgagagaa accgaaaggt ggtgtcatta
     7321 tctggaataa cgagatagac catagttttc tgcgtccccc atgtctttaa gtccaaggta
     7381 tcacgcttgg ttaagtcaat gacggattgg atattaaaga gggcaaactt agcagttgtt
     7441 acagcaatca ccgaatccag ggtcttatcc ttgtagtttt ggaagtctgc ccagttacgc
     7501 atggtaaagt tctccgttcc ataggtcttg gcatagctct caaacatgac ttctaagaca
     7561 ctcttatctt gattttcccc tttggataag agcttgatga gttttccaat ttctgaaaag
     7621 gctgggtaac gcccacgctt acggcgactg tctgcttctt ccttggtact accaggagga
     7681 ttgtaaaaat ccactaagta agaggaaatg gctctcacta aggtcatgga agcttcatcc
     7741 caaaagggat cactgcgact gccattgcct ttggtattat tgaaatagac cgtaagcata
     7801 cggttcaaat cattctccgt ttccacataa cgaaagggat taaagccatc tgagttggtc
     7861 atgtttacga ggtctaagac cttgacctga tagccgtttt ctaaaaagag cttccctgtc
     7921 ttttcagcta agtggtcctt aggatcaacg acaatattgg aacagttaag ctgaatcaga
     7981 ttgggtttga caaagcgaaa ggttttccct gatcctgatc caccaatgac cactaagttc
     8041 ttgtttcggt caaattgtgg ggctttcttt tctaagagag ttagcctaac gtttcgagat
     8101 aagatagtat cgttcaaggg gttcttactg ataaaggctt tacgctcccg attgtttcca
     8161 aaacgagcag agccatactc agccccttct cggtagactc tctgaccagt tgagacgtaa
     8221 agatagacta gtcccatcgt cacaaatcca aaacaaaacc ctaaaaccga tctaccagta
     8281 aagttgccct tccacaaggg atttaaaacc tgattctgac cttctcctaa gagataggca
     8341 aacctttcaa tcgatggttg atttgggaga ctatcgtaaa gcaagactag gcgatggcaa
     8401 aaatagccaa aggcaagtcc taaaacacca aagataaaag cttttttccc tgaggccatt
     8461 agagaattac ctccttggcc ttcacagcag aaggttctga catcacaatc tgttccttgg
     8521 ctttagcgat ttcctcatct aaggttttat ccagagttaa gccttgcagt ttttcgggat
     8581 tggaaaccaa cttctgaagc aacttatcca agtgcttatc taacaaagat ttatccttag
     8641 catagaaata aaggtagtct ccctgccaac taatggcaat aggcagattc tccgattcca
     8701 tcagttcctt gaatttctcg acatcaatgg gtttatccaa gatgtctttt gagatattaa
     8761 gccactcaat ggcataaggg ctttgaagga gttcttctaa cttttgaacc ccaatcttat
     8821 aggccgagtc ttgtgccaaa gcttgtctag cggaccactc taagagcttg aggagaaccc
     8881 taacggtaaa catagtgctt ctctctgcgt actgtaacgc ttggcgttcc tgttgttcgg
     8941 atgacatcat tccctccttg gcatgattcc cttataaaca ctagggtgct ttcatgatac
     9001 gaaagtaccc ttgattttgg tatcacaaca aagacaggaa aaagacaatt ccattccaag
     9061 acaaatgaac gagggttgag gtgaaacaat cagcctttaa gcgaactagt cctagcacca
     9121 gtcctaaact accataaagc ccccaagtga tgagactaga tgggtgatgg gctaaagtaa
     9181 agaggaaact cgttaacaga aactgaacca caggttgaga caagactccc cacagcactt
     9241 ctctgtaaaa tacttcttcc accacactgg cattgaggag aaagaggata aaaggcaaca
     9301 ttggtgcttg atcttgaacc gtcactaacg tttcttggtt caccgcatat cctgaaaaga
     9361 tggcactcat gataagagcc gtactcacca tgacaccaag actgacaagc aaccaaagcc
     9421 ctctctcttt taaggataaa tttcttttag gtatcttaaa acatttccag acccacagta
     9481 caagagcaaa aaaagaaact tgtaaggcta ttagcactac ctcatttagc actcctacca
     9541 aaaagaaact aaccaaaaga acattaacat gaatggctcc gtacgccagc aatatccttc
     9601 tcatgtctac ctcctaaaca agtcttcata gtcaatctct aagacgctca ccactttctc
     9661 cacccatttg acttgtggca tgaggtgatg agatttgtag tgacgaaagg tttggtagag
     9721 acgtttaaac tcactaggat aaacgtattg acccttaaac atctttcgag cgagatcagc
     9781 ccatgacatg cctctttcaa taacgatact ttccaaattt tcccaaaagc ggtcgttcat
     9841 agctcctcct tattctgtta gttgcttaaa gaggtgctca cgaaaagaca ccaccttatg
     9901 agttcttggt agaaaggttc tcgcttcttc taaactcata tcgggataca ctttatcctc
     9961 acaaatcacc agaggtaatc gcaaattctg atcaggtttc ctgagaacca acgtgactaa
    10021 ttcacttaat ttcatctctc tatgaccttt aaaccgttgt agagaagggg ataagagggc
    10081 aaaacaatca ctgcttttgg taaacaagct cagtaagtcc tcacgtgaca agtcattcac
    10141 ttctttagga gtgtaagaaa taccatgcgt gtcataaaaa gaaaggagat tttgatttcg
    10201 actggtattt cgacttaaat agatttctag catttcttcc tcctacaccg ataaatcctt
    10261 tggtaatttt tgagtaagag gagtaaacac cttactcata tcaatgggtg tcctgccttc
    10321 accgaaactt tttactgtaa tccgtgtggt caataaatcg tcttttccat ttgccatata
    10381 gtgttgacca aaagctctaa aaacgagatg gttctcttct gctagataac tgtcaacgcc
    10441 atttttaagg tcttgcgttt ccataaactc aaagagtcga tgtaagttgg actcgtaagc
    10501 caatggaaca ttcatctcct gatggtaatc atcttcaaaa gtgacctcaa tctcacaatc
    10561 atagttgggt aaagaagcaa tcgtctcagc aatcctttct acctctgctt gatgaataac
    10621 ttcttccagc tctgtacagt ccctaatact tttagtgtgt aataatttca tgtccttctt
    10681 cctcttcaat ctttctaaat tctctagcaa tagcttcaat gacggtgaca gtcacactat
    10741 tgcctgcttg tttgtacaac tgacttttac ttgatacgct ttctgctctt tcataagccc
    10801 agtcaggaaa cccctgaagt ctaaaacact ctctaggggt caatcgtctg attctcaaac
    10861 gataaagttt tccatctagg attattcctg tcacttcata ccacttgtcc ttacggtatt
    10921 caagagcagc taccaccact cccatattgt cagaagtggt taaggtattt gagattccct
    10981 ttcctactcg tcctctgcgt ttggttgact ctggataagc aaggttgaca gaatctccca
    11041 ctgttgcctt agcatagcct aatttggtcg cttccttgat tttcaaatgc ggagcttctt
    11101 cacggcagat aatcttaggc actttatccc ctccttgcat ggtggtaagg gtaggggata
    11161 ggccagactg gtcatagact cgcccagttt gcacaaaaga ggtcggaagg gttcctgcga
    11221 caacaacacc gtgtctatct tgaaccgtta gggtaaacat ggggtcttga ttgtccttaa
    11281 aacgtctgcc atgttggcgt ttctccagtc tatcaggggt taagactgga atggcaatct
    11341 ttgcttcttc tcctttattt tgcgtcaaag taggcgagag acctgttgct aggtagacct
    11401 caccgttcat gccttttctg gacggattga catttcctaa tctttcaaga tgagctgagc
    11461 tattttctcc tctgagagga aataagaatc tgggatggta tcttctagaa tgtccgataa
    11521 taaagaccct ttctcggttt tgtgggactt ggaaatcttt actgttaagc acctgccatt
    11581 cgatatcata ccccagctca tccaatgtag agaggattgt ggcaaacgtc tctcccttgt
    11641 cgtgactgag taaacccttg acattttcga ggaataaaaa acgtggttgg atctgtttgg
    11701 ccgctcgagc aatctcaaag aacagagtac ccctagtgtc ctcaaatccc aatcgtctgc
    11761 ctgcgagtga aaatgcttga caagggaatc ccccacagat gatgtccacc tgccctctga
    11821 gttgtctaaa gtcttggtct gtgacttgtc taatgtcatg aaattctatt tctccttccg
    11881 tatcatagat gactttgtaa gatttcctcg caaacttgtc aatctcacaa aaaccaatac
    11941 attcatggcc ttgacgagtt aaccccagtc gaaagcctcc aattccagca aataaatcta
    12001 aaaacttcat gtctctcctt cctttctgac aaaactaaaa ggaccttaca ttttacgtaa
    12061 cgtcctacct caattataat cgtccatgtc tggtgccgtg atgattgcaa caattagcca
    12121 aatcaaccct agtctccaga ttcctaatac gatccaccaa aacatctgtt caccaaccac
    12181 ctttcttcgc ttcatttagt cgtatctgct tactccattc ggatagaacc ccattaaaga
    12241 catattcagc aatcgcttca gcggtattta caaaacgcat gtgctctaaa gcataccgat
    12301 aacgatcctc aaaatgaacc atcgcatatt cactcgtaac tcgagacaag ccttcttgtc
    12361 gcaagcgttc atagaccaaa ttccaaatat agcctacgtc gtattttgtc acatgatcaa
    12421 ctttacgagt gagagattct tcttgttttt ttccaaaagt gacttctttt ttctcctcct
    12481 cgtcctcaat gactgactca tttctttcag tctcattttt cttagtctca cttatttcag
    12541 tctcactagg ggctgaattt aagacctgcc ccgtttgttt ttgagactgc ccccgtgttt
    12601 ttttaacacc acccccgtct gattttaaga cggggctagt gtcatcttcc aactccccta
    12661 aataaatctt attggccaag cgcccttttt cactagaaga ctgttggact tcatcaatca
    12721 agccatactc tcttaacgtt ttcttaatcg tcagcaactt tgacttggaa cacccaagga
    12781 gagccatcag ttttgagttg gaataaacca aataaatagc cccctcttca tcaatccagc
    12841 ctttactcaa agataattcc aaacgatctt ttaaaacagc ataggctacc ttgacttcta
    12901 gtttcatatc cttataacgc tcactctcaa acaagagttt tgggagctta tagtaacgct
    12961 ctgacgtttg atagtgattt gcggtaatgc gtttcatgat tgtccctcca atactaatac
    13021 tgtgacatct ccatttgatt caaagcaaac caagccttca tgttccaagc ctgagaccaa
    13081 gtgattggcc tcctcaatat caacactcat gacatccatg agataaccca ccacaacttg
    13141 acgtgatgac tgttctttct tttgcatatt ttcctcctga aaataaaaaa gcgagaacac
    13201 ctattaaaat gttctcgcta tagcgatatt ctcttattaa aacaaaaatt tcctccttaa
    13261 tgacagattg tagaacgctc aaatccttga tttatcagcg ttttaagcac ctatcattat
    13321 tatgacacaa tccccgctgc acaacctaaa gcagcaacta cagctgctcc tccggaatta
    13381 cctccgtaaa cctcactcag cattgtttca tttatattac aataagtatt catacaagtc
    13441 tccttttgtt aaaatccacc cgttgcccct gttactcctg cccaaagagc cacaccaaat
    13501 ttagctccta tgtatccaca tgctcccata aatggtgctc caacaccact cgcagcacaa
    13561 atagctgtcc ctaaccccca gccaccaaaa gcggcaccac caccttctaa gacattagtt
    13621 tgccaattat tcttgcctcc ttcaatacta gataacatag ttatatccat aatctcaaat
    13681 tgttccatca tttttgtatt catgacaaat actccttttt tattttttat ttttgtcttg
    13741 ttgtaacctt gacaagttta gtatatcatt attttttaat ttttttcatc caaatcttga
    13801 actgtcatcg aaacgtcttg aattagcttt tttatttcaa gccacctcta aatgtttaaa
    13861 aaaaataatt tctaatcact tttttaccat tcaggaagtt ttaatgacta ttcaagattt
    13921 cataaaatat gaacttattt ttatggcata atatacctat ccactatatt aaaggaattg
    13981 ccaatgactt cttataaacg tacatttgtt cctcaaatag atgcgagaga ctgtggtgtc
    14041 gctgccttag cctcgattgc taaattctat ggttcagatt tttctctagc tcacttgaga
    14101 gaacttgcaa agaccaataa agaagggacg actgctcttg gcattgtaaa agccgctgat
    14161 gaaatgggct ttgaaacaag gcctgttcaa gcagataaaa ctctctttga catgagtgat
    14221 gtcccctatc catttatcgt tcacgttaac aaagaaggaa aactccaaca ttactatgtt
    14281 gtctatcaaa caaagaaaga ctatctgatt attggtgatc ctgacccttc tgtaaaaatc
    14341 accaaaatgt caaaagaacg ctttttctct gaatggactg gagtagctat ttttctagct
    14401 cccaaaccca gctatcaacc ccataaagat aaaaagaatg gtctactaag cttccttcct
    14461 ctgattttca aacaaaaatc tctcattgct tacattgttc tctcaagctt attggtcact
    14521 attatcaata tcggtggttc ttattatctc caaggaatct tggatgaata catcctaaat
    14581 cagatgaaat caactttagg aatcatctca gttggtctgg ttattaccta tatcctccaa
    14641 caagtcatga gcttctccag agattatctc ctaactgttc tgagtcagag attaagtatt
    14701 gatgtgattt tatcctatat tcgccatatt tttgaacttc ctatgtcttt ctttgcgaca
    14761 cgtcgtacag gagaaatcat ttcacggttc acagatgcta actctattat agatgccttg
    14821 gcttctacca ttctttctct ttttctggat gtttctattc tgattcttgt agggggagtc
    14881 ttactggcac aaaatcctaa tctcttcctt ctttctctta tttccatccc tatatacatg
    14941 ttcatcatct tttcttttat gaagcctttc gaaaaaatga accatgatgt catgcaaagt
    15001 aattctatgg ttagctctgc cattatcgaa gatatcaacg ggattgaaac tataaagtcg
    15061 ctcacgagtg aagaaaatcg ctatcaaaat atagacagcg aatttgtaga ttatttggaa
    15121 aaatccttta agctcagtaa atattctatt ttacaaacga gtttaaagca gggaacaaaa
    15181 ttagttctga atatccttat cctatggttt ggcgctcaat tagtcatgtc gagtaaaatt
    15241 tctatcggtc agctaattac ctttaacaca cttttttctt actttacaac tcctatggaa
    15301 aatattatca acctccaaac caaactccaa tctgcgaagg tcgctaataa ccgtttgaac
    15361 gaagtctatc tagtcgaatc tgaatttcaa gttcaagaaa accctgttca ttcacatttt
    15421 ttgatgggcg atattgaatt tgatgacctt tcttataagt atggttttgg acgagatacc
    15481 ttaacagata ttaatctcac gattaaacaa ggagataagg ttagcctagt tggagttagt
    15541 ggttctggta aaacaacttt agccaaaatg attgtcaatt tctttgaacc ctacaaaggg
    15601 catatttcca tcaatcatca ggatattaaa aacatcgata aaaaagtctt gcgccgtcat
    15661 attaattacc taccacaaca agcctatatc tttaatggct ctattttgga aaacttaacc
    15721 ttgggcggta atcatatgat tagccaagaa gatattctaa aagcttgtga attagctgaa
    15781 attcgtcaag acattgaaag aatgcctatg gactatcaaa ctcagctctc tgatggagct
    15841 ggtctatcag gaggacaaaa gcaacgaatc gctctcgctc gtgctctttt aactaaagct
    15901 cctgttttaa tactagatga agctactagc ggtcttgatg tctttactga gaaaaaggtt
    15961 atagataatc ttatatccct aactgataaa accattctct ttgtagccca tcgtctcagt
    16021 atagccgaac gaactaaccg tgtcattgtt cttgaccagg ggaaaatcat tgaagttggt
    16081 agtcaccaag agttaatgca ggcgcaaggc ttctaccatc atctattcaa taaataagga
    16141 gaatgttatg aatcctaatc tttttagaag cgtcgagttt tatcagagac gttaccataa
    16201 ctatgcgaca gtgttaatta tacctctttc attactgttt actttcatct tgattttctc
    16261 ctttgttgcc acaaaagaaa ttactgttac ttcccaagga gaaatcgccc ctacaagtgc
    16321 cattgcatct attcagtcga ccagtgataa tcctatcctt gctaatcatt tagtggcaaa
    16381 tcaagtagtt gagaaaggtg acttactcat caaatactct gaaacaatgg aagaaagtca
    16441 gaaaactgcc ttagcaactc aattacaaag acttgagaag caaaaagaag gacttggaat
    16501 tttgaaacaa agcttagaaa aagcgactga tcttttttct ggcgaggatg aatttggcta
    16561 ccataatacc tttaggaatt ttactaaaca atcccatgat attgagctag gtatctcaaa
    16621 gactaacacc gaggtttcaa atcaagctaa tcttgccaat agcagttcat cagccatcga
    16681 acaagaaatt acaaaagttc aacaacaaat tggagaatac caggagctga gagatgctat
    16741 cataaataaa agggctcgct taccaactgg caatccgcac cagtcaattt taaatcgtta
    16801 tcttgtagcc gctcaaggac aaacacaagg aactgcagag gagccatttt tatctcaaat
    16861 taatcaaagt attgcaggtc tggaatcatc tatcgcaagc ctcaaaattc agcaagctgg
    16921 tatcggaagt gtagcaactt atgataatag tttagcaacc aaaattgaag tactccgcac
    16981 tcaattttta cagacagcct cacagcaaca actaaccgtg gagaatcaat taacagaatt
    17041 aaaagtacaa ctagatcaag cgacacagcg cttagaaaac aataccttaa cagcaccaag
    17101 taaaggtatc attcacctaa gcagtgaatt tgaaggtaaa aatagaattc caactggtac
    17161 agaaattgct caaatattcc ctatcatcac agatacaaga gaagtactaa tcacttacta
    17221 cgtagcttct gactatctac ctctactaga taaaggacaa actgtaagat taaaactgga
    17281 gaagattgga aatcactgca ttaccatcat cgcccaactt cagacaattg atcaaactcc
    17341 taccagaaca gagcaaggca atctctttaa attaaccgct cttgcaaaac tatctaatga
    17401 ggatagtaaa ctcatccaat atggcttaca aggtcgcgtc actagtgtaa ccgcaaagaa
    17461 aacatatttt gattatttca aagataaaat tctaacccat tctgattaat tttcagataa
    17521 cactctataa ctatttatta tcttatcaaa aaggagaatt gtaacatgga taagaatcaa
    17581 aacctaactt cattccaaga actaacaact actgaactca accaaattac aggcggagga
    17641 tggtggaaag atttattaca tagatttaat gtaattgaac aaaacaatac aaaaggattt
    17701 aatcaaccaa tacaactata aaaaataaga ccgagaaaca agaattctcg gtcttatttt
    17761 catcattctg tatgtatcat agtaagcacc tgacgaaaga cttgatcttg acaggtagta
    17821 tttaaactgg cattgggata actttccaca atcttcataa cggtatagag accgacacct
    17881 ctctcctccc ctttagaact aactccaaag gagaagattt cagaaatatc gatgccctct
    17941 tctttgatag aattttcaat gataaaggtc tcctgtgctc cattttttaa aaaggcaatt
    18001 gaaacatgag gttgactagc ctctgcactc gcttcaatag cattgtcaca aaggatagac
    18061 acgatggtta gaaaatcaag caggctcatc ccctcgacct gaatctcctc aggaacttcg
    18121 acattaaaga taatcttctt atctctagct tttagaaatt tccctgctag aagacttttg
    18181 agggcacggt cacgaatatt caccaatctg cccaggtcat atttattgtc ctgcaatttc
    18241 tgactggaat cctttaaaac agagtcgtaa acctctttta tctgctccat atcctcctct
    18301 tcaataccca gacgtaaact ggtcaagagg ttggtgtagt catggcgaaa actccttact
    18361 tccttgtaaa gttcctctat atgccgacta tggcgttcca tatctctata gcgcaaggtc
    18421 tgctcttggt tcagtctctc atggagtttg ttcttcaaat aggtatccaa tttcttgata
    18481 acccccataa aaaataggag gtagaacact aggatgagat ggcgaacagt cgttgattga
    18541 ataccttgct catattcaaa gtaagacaga ctttgtatca ccaaatagta agcccccatt
    18601 atccagttaa tcttagtcag ggacttttga aaacctgtat ctagaatctc ccttctcaaa
    18661 ctagtaaaat catagtccaa ccatttcaaa aaggctagag aaatgaagaa attgaaaatt
    18721 attatacata acccagtgaa tgagtagcca tcatatactt gcccttgtcc caaaaatgga
    18781 agcacaaaat aggagactcc tctataaaag agattcacca atatcattgg aaagagacca
    18841 taaaagaaaa ggagtttttt aggaagccct cttaacaata agaaagacaa gcctatgccg
    18901 tacaagggtt ccataaaata agataggtaa acatttccta ctatatagct aatcattaca
    18961 aaaacaaaga ccaacagtat cttcaaaaga aaggccttaa aaatcctctc gaaagtaaga
    19021 ttaattccat ccaccttaaa gaaaatgaca atttctagcc cattagtaat aagtgtatgc
    19081 aataatatcc aaacaatatt cataaactct cctagttcag tgtaagttat taatagcctc
    19141 agacacttcc ctgaccttat aacgcacgat cagacaactt ccaccattgg gaaggaaaag
    19201 gagtttttct ttcttatcca aatgcaccac atttgcagga ttgatgagaa aagagcgatg
    19261 gcactgcaag agacggggtt cctgcttgaa aacctcctct aaactcgctg taaattccag
    19321 cctgtctgtc ttggtataga gaataacacg atgggctctg ggagacattt cgagatagta
    19381 aacctcttta aaaggatatt ggaattgggc aaattttgat ttaaagtaaa agcaatcttc
    19441 cgccagactt ttactatctt gactattggc atagaggagg gctgtctcga tacgagattc
    19501 aaactcctct gccgaaaggg ccttatcaat gtagtccaaa gctgacactt ggtagcgaaa
    19561 ggacagaggc ataaactccg agtgagtcgt cacaaagacg attagggcat aagggtcccg
    19621 atcccgaatc tttctagcca cttccagccc cttcatctcc tcatttcgaa tctcaatgtc
    19681 caaaaagaat agctgatggg ccccccttct catgcacctc tgtcagcagt tggtccggct
    19741 tgccaaatac ctcaaaagag ctaggaatga tatgatgtgc tttcaaaagt ttctcaatcg
    19801 tcgtttcaat tctagtctgt tgggaaaaat catcttctaa aacaaatatt ctcatcttct
    19861 tactctccct ctttcaacca tttttgacga atttctctat agcgacgtct ggcatacttg
    19921 acagcgtatt gaccttcttc tccgagaaaa aggattcttt tttgaaaatc aatcgatttt
    19981 aatttatcaa gattaaccaa acaatttcga tgacatctca tcaaggtttc cccatattgg
    20041 ttctcaagat tacttaaatt ttgaagcata ttaaaactag cttcttctgt aacaatctgt
    20101 acggtatggg ctttagttgg atgtgtttgg atatagtaga tatcgtcgac gtttacttta
    20161 tagactgttt tctgcgtctg aataatcata tgtttcattg gattctcctc ctaagaaaag
    20221 aataacagaa aagttctagc ccaagcccac ccaatcctaa acagtctttg aaagctccta
    20281 aaaggattat ttttctacaa catcatgatg agcttacaac tattttatca taaaattcac
    20341 tcagcgcaat taaagatttg aataaaaaaa aagaattaaa aatgataaac taacagtatc
    20401 aaaacacagt tgccagaagt aagactggca cccagattaa aggaggaatt cccatgacag
    20461 atacagaccc tatcaaaaga gctcaggctt tgattactga cttaaacaaa gcctatcaag
    20521 catgcaaaca ggcaagcgct gacgacgtcc gctttcagga gcaattaaac tctattcttg
    20581 gttttctagc caaggctgag acagcggata atcgagtctt gattgaactg gaaaaatttt
    20641 accagacttc cagtcttctc atgggactca gcgctcttga tccagatgct ccaactcgcg
    20701 ccgcttggcg ggcctatgac cgcttccact ttgaccaagt caagaccaag ttgagcctct
    20761 acggtccaac cattatcttg taaaaaataa aagaagctga gacagattga actcaacttc
    20821 ttttttgttc catataagca atgttagtcc tgcatctgac gttttacctg ataaggcaaa
    20881 tacaagactt gtaaaaccaa acctgcaccc agcaaggcta gaagggctag tttttcttgg
    20941 aaggtcacaa ggccgacaac taattccacc actaagacca aactagtcaa tcctcggact
    21001 accgcctgca agcctttttc cttttgcccc ttgtccagcg gaaaaagttg ggtcaaatac
    21061 tggtagtcaa aggcgtgata gagggccagc aactgaaaga gcaagaggta gttaaacaga
    21121 accactaccg ctgtcgcaat ccaagattgc tcaataaaga cctgcgccag caaagaaagc
    21181 aagagcagac ggagactaag ggcaaaaagg tctccatttc gcaaataaga acgcagatag
    21241 agattttgcc aaatcttccc aggcaccttc tgaacaacct ttagaataaa gtccagatag
    21301 gcacgacgct tgacgctgtt tgaaattccc ttgacctgcg taaagagggc aaagaaacga
    21361 agcaagactt gcttacgctt gctttcttgg gaaatgacat agtcccaatc cagtccagtt
    21421 tcagtgaaaa atttgctggc cttttgacga aagaggaaat attttcctac ccccaataaa
    21481 agcacataaa ccagaaaaac aggcaagcca taacccatgg ctaaaaacaa gggcgcaaat
    21541 aaaagcaaga agagggtctg gacaaaaatc caaaagacta gggaaatgcc ggtttgacgc
    21601 ttgagatgga gcttgatttc ctcttctcca actaagagaa agagcttgtc tggagcctcc
    21661 atataggtgg caattcctcc ccaaagtaaa agtaaaacag acgtaattcc tacaaacaaa
    21721 aggataggcc aatgattttc aggaaaatgt tgtaagagtt gactgtactg gtaggctaga
    21781 aagcccaaca gtacaagcag gaacaagaca aagtggtcat tgagaacata gcgcagataa
    21841 ccaagacact ccttacgaaa ggcctgcttt ctctttaaaa acaagtcttt cataggtcct
    21901 cctcttttgt cagagccaag taaatatcat tcaaactagc ctcaggcata tcaaaggctt
    21961 cgcgtagttg caggagattg cctttggcac gcacctctcc cttgtgaaga atgacaaagg
    22021 catcacacat cttctccgcc gaatccagca cgtgggtact catgagaata gacttgccct
    22081 tttgcttctc cacttccaaa agctgaatca aatcagaaat agccagcgga tcaagaccaa
    22141 ggaaaggctc atccacgatg aaaagacttg gatccaccac aaaagcacag ataatcatga
    22201 ccttctgctt catccctttt gaaaaatgaa cagggaacca gtctaatttc tgttccaaac
    22261 ggaacatttt taacaagggc tctactcgtt cgaaagccac tttttgctca ataccgtaag
    22321 ccatagcaac cgtttcgata tgctctctga gggtcaattc cttatacaga ctaggcgtct
    22381 caggaatgta gccaatctgc ttgcggtagc tagtcgcatc tccttgcaga gtcaggccat
    22441 tgatattgat ggagccacta taaggtgcca acagaccgat aatctcattg atcgtcgttg
    22501 atttcccagc accattgaga ccaatcaaac cgaccaactg cccactttca acagtaaagg
    22561 acacatcttt caaaacagga acatgaacat agccacctgt caggttttta atttctaaca
    22621 tattttctcc aaatctggta taatgtagct atattatatc aaaattcagt acagtagagg
    22681 tagattttat gtcagattgc attttttgta aaatcatcgc aggggaaatc cctgcttcaa
    22741 aagtatatga agatgagcag gtccttgcct ttcttgatat ctctcaagta acactaggac
    22801 acaccttggt cgtgccaaaa gaacactatc gcaatctttt ggagatggat gctacgagcg
    22861 ccagccaact ctttgcccaa gtaccaaaag tagctcaaaa agtcatgaaa gtcactaagg
    22921 ctgctggtat gaatatcatt tccaactgtg aagaagtcgc tggtcaaaca gtttttcata
    22981 ctcacgttca ccttgtgcct cgctacagtg ctgacgatga cctcaagatt gattttatcg
    23041 cccacgaacc agactttgac aaacttgctc aagttgctga aaccatcaaa aacgcttaag
    23101 gagttgctat gaaattatcc aacctactgc tatttgcagg agctacagcc ggaagttatc
    23161 tggttacaaa aaatcgccaa accatcacag atgaaatctt gaataccact gaccgcgttc
    23221 aagctatcaa ggacgatgtg gatattatcc aaaacagcct gcaaatcatc gaccagcaaa
    23281 aagaacttat caaggaatac caagaagact tgacttacaa gtttaagatc ttggaaaagg
    23341 atatccagac tagactagct gtgataaaag aaatgcaggg aactgaagat aagtaaaaag
    23401 agcccccggc tcttttttaa aacgtaaaca agttatagtg aattgaattt agaatagcac
    23461 atcatagttt ctaaagcatt gttagagatt actttaaaat cctcttatca atttgttcat
    23521 attctatttc aatctactat atatatccca tcaactatgc atcataattt aggtaactca
    23581 tactcaataa aaatcaaaaa gcaaactaga aagctaggca cagactgctc aaaacaccgt
    23641 tttaaggttg tggatagaac tgacaaagtc agctcaaaac actgttttga ggttgtggat
    23701 agaactgacg aagtcagtaa ccatacccat ggcaagccga cactgacgtg gtttgaagag
    23761 atttttgaag agtatcattc accatttcac aactaaatcg aagactttct gccgtaatga
    23821 aaacacctga aacagcttgg tttcagctgt ccggaaactt taagacttag gttcaaagtt
    23881 taggtatgga acttcgaagg aggtcgctac cgtccgtcat tacttaggaa agtcttaaaa
    23941 aatctataaa gtaaaaagag cccgacagct ctttttgttt atactcaatg aaaatcaaaa
    24001 agcaaattag ccacgggctg ctcaaaacac tgttttgagg ttgtagatac gactgacgaa
    24061 gtcagtcaca tatatacggc aaggcaacgc tgacgtggtt tgaagagatt ttcgaagagt
    24121 attattctcc atcaaaggca tctttaatat ggtcaaagaa gccttttttc tttggattta
    24181 ctttcaagtc accagcagcc gcgaattctt tcaaggctac tttttggcgg tcgttcaagc
    24241 ctgtcggtgt tacgacatta acagtaacgt attggtcacc aactgcaccg ccacgaaggc
    24301 tcggtgcccc cttactacgt aggcggaact tcttaccagt ctgagttccc tctggaataa
    24361 ccaattcaac atcaccgtga acagttggaa tatctactgt atcaccaaga gccgcttgga
    24421 caaagttgag gttgagattg tagaagatag tcgttccttc acgttcaaac ttgtcgctag
    24481 cttccacaga aactactaca tacaagtcac cataaggtcc accgttaaag cctgcttcac
    24541 cttgaccagc gaggcgaatt tgttgacctg tttccacacc agcagggatt ttcacatgta
    24601 cgctatgagc ttgtttctca tgacctgttc catgacaggt tgtacatgga tatttgattt
    24661 cttttcctcg accgtgacag acatcacagg ttacttggcg acgcatcata ccaagaggag
    24721 tctgcgtatc gacgttaatg acaccagcgc catgacagcg tccacaagtg actggactcg
    24781 tccctggctt agcaccagag ccattacatg tacgacagcc agcttcacga tgatacttaa
    24841 cttccttctc agttccgaag atagcttctt caaaggtcaa attgacacga tactggagat
    24901 catctccttg gcgaggagcg tttggattgc gcgaagaacc gcctccgccg aagaaacttg
    24961 agaaaatatc ctcaaaacca ccgaagccac ctgccccatt gaaaccgccg aaaccaccag
    25021 ctccaccaaa accaccattg gcacctgcag caccatactg gtcataggca gcacgttttt
    25081 ggtcgtcact caaagtctca taggcttctt gaacttcctt gtacttgtcc tcagcaccag
    25141 gctccttgtt gatatctggg tgatattttt tggaaagctt acgataagcc tttttgattt
    25201 cgtctgccga agcgtttttg gataccccca gacgatcata aaattcagta ttgttcataa
    25261 ttcaagatac aaagggcgtc aaacggacac agccatctag gagttttgac gacggacgct
    25321 tacgtcctag agaaaactat ctttttggca cagtccgtag cccgtgttca gttacgaaca
    25381 cccttattcc tttctattga tgttctgaat cgaaccacca tttaggtcgg attcaattcc
    25441 tttcttttat atttagtaag aaattctgaa acccgtgttc agttacgaac actctttgtt
    25501 cctttctatt gatgagacaa aacccaaaca aatgagattc cgtccctttt tatcgaaaaa
    25561 cagaggctgg gttgcaacct ctgcaaataa gtaaattaac tttattttga ttttaaatat
    25621 cctataagta cagaaatatt tatatatttt tgtctcttct tagtatttgc tatataattc
    25681 caattgatca taagaaatac aactactgtc caaatcacac caattatgaa cggtattaca
    25741 aatttatatg tttgtatttc taatgatatc atagctgata ccagcgccga tacaaatgca
    25801 gacaacaata ctgaggtaac aaaattcctt accgcttcat catttttgat acaactatca
    25861 tgttcagcta atataatttc tctatatcta gctaaatatt ctattggaat attatcaata
    25921 aaatcttttg atgttctata gttatcagct tgattacaaa aatcattata aacttttcgt
    25981 gtatttttta gatactcttc atccaataca ctcgtcttac ttttccgtaa actctccgtc
    26041 tacgacgtca tcgcctgcgt ttcctgtttc ttgtgcgcct tctgctcctt cttgagcttg
    26101 ttgcgctgct gcggcttgtt cgtagagttt aacagcaagt ccttgagctt tttcgttcaa
    26161 tgcttcaagt tttgttttca tgtcgtccaa gttgttgtct tcttgagctt tcttaaggtc
    26221 atcaagggca gcttgggcag cgtcacgttc tgcgtcgaag cctttacctt cagtttcctt
    26281 gattgtcttt tcagtcgcaa agattgcttg gtctacttca ttacgaaggt ctacttcttc
    26341 tttacgtttc ttatcggctt cagcgtttgc ttctgcatct ttcatcatgc ggtcgatttc
    26401 ttcgtcagtc aaacctgagt tcgattggat gacaatagtt tgttcttttt gagttccaag
    26461 gtctttggcc ttaacagaca cgataccgtt cttgtcgatg tcaaatgtta cttcgatttg
    26521 aggaattcca cgaggtgcag ctgggatatc agtcaattgg aagcgtccaa gagtcttgtt
    26581 atctgctgcc attgggcgtt caccttgaag aacgtggata tcaacggctg gttggttgtc
    26641 tgctgctgtt gagaagactt gtgatttaga tgttgggatt gtagtgttgc gatcgataag
    26701 ttttgtaaat actccaccca ttgtttcgat accaagtgac aatggcgtta catcaagaag
    26761 gacaacgtcc ttgacatcac cagcaatcac accaccttgg atagccgcac ccatagcaac
    26821 tacttcatca gggtttactg atttgtttgg ttctttacca gtttcagctt taacagcttc
    26881 aacaacggca gggatacgag ttgaaccacc aacaaggata acttcgtcga tttctgacaa
    26941 gctcaaacct gcatctgaaa gggcttgacg aactggaact tttgtacgtt caacaaggtc
    27001 acgagtcaaa tcgtcaaatt tcgcacgagt caaagtcatt tccaagtgaa gaggtccagc
    27061 ctcacctgca gtgataaatg gcaagctgat ttgtgttgaa gttacaccag aaaggtcttt
    27121 cttcgctttt tcagccgcat ctttcaaacg ttgcattgcc atcttgtcag tagacaagtc
    27181 gataccgttt tctttcttga attctgctac caagtggtca atgatttttt ggtcaaagtc
    27241 gtcaccacca agtttgttgt cccctgcagt tgacaatacg tcgaagacac cgtcacccaa
    27301 ttcaaggata gagacgtcga atgtaccacc accaaggtca aataccaata ttttttcttc
    27361 tttgtcagtc ttgtccaaac cataagcaag agctgctgca gttggttcgt taacaatacg
    27421 ttctacttca agaccagcaa ttttaccagc gtcttttgtt gcttgacgtt gagcgtcgtt
    27481 gaagtaagct ggaactgtga taacagcttt ggttactttc tcaccaaggt agtcttcagc
    27541 gtagcctttc aagtattgaa ggatcatagc tgagatttct tgtggagtgt attcttttcc
    27601 atttgcagaa actttttcag aagttcccat cttagatttg atagagataa ctgtatctga
    27661 gtttgtgact gcttgacgtt ttgcagcatc accaacgatg atttctccgt ttttgaatga
    27721 gactacagat ggagttgtgc ggtttccttc tgggtttgcg atgattttgc tttcagttcc
    27781 ttcaagaact gcaactgctg agtttgttgt acctaagtca ataccgataa ttttagacat
    27841 gtgtttttct ccttgttagt taattttcta tttttctttt tgatactctt cttaagtggc
    27901 gacgccgtca gagcttgact tcgtcagtct ctttgactaa actttgagcc taaggtctca
    27961 aaatttgcgc aaatagcgcc acggcgaaga gtatcgtctt tggttcgctt cgctcactat
    28021 tacaaagcaa aacatatttt atctttcttc atagtttatt gtcgtttcgg acaagttttc
    28081 tattatgtaa attgcgacac gaggagtcga aatcgatttt atttcgacga cgagttagta
    28141 aggaagctag gcaaacgcca tagcaattgc cgttttctga cgagttgctt tagctaccgt
    28201 cagaattgcc gaatcgaaca cgccctaagc tctgagtaaa aataggagat tttcttgtgt
    28261 tcatcgaaca cttcgtcaat ctcctatttt tactgcgagc tttttacggg ctttgtatct
    28321 tagttataca ccactaccat tgctgggcgt aggatgcggt catggagttt gtagcctttt
    28381 tgaaagactt gggcgatggt atctactggg tgttcatcgt ctgctgggag agtttggatg
    28441 gccatatggt agttatggtc aaattcgcca tctgctgcga tttcttcaat tccttcttct
    28501 ttcaaagcgt gaatcaagct ttcttgcacc atccccaagc ccttcttcac atcatctgtc
    28561 aaaccttcaa ctgcaagtgc acgctcaagg ttgtcaagag atggtaagat tgcttttgcc
    28621 aagtcctggc tacgataacg ttgcaagttt tgacgttctt cattggcacg gcgttggata
    28681 ttttgcattt ctgcatgagc gcgaagatat ttgttttcga actcatctgc acgttcattt
    28741 gccaagtcca actcagactt ttcaggagtt gtttcttcag ctgtttccac aacttcctct
    28801 tcttgaactt cttctacttc ttcatttttt atatcttggg ccatgttcgc ctcctttaat
    28861 gatttcaatc ttaatgtact tcgtaatgat tactgctgag gtagaggtaa aaatctgtca
    28921 acttcatggt caaaacacgg ttgaccacat tgacttgatt gattagctgt tggtaatcca
    28981 gattaaccgg accgataatg gctagaattc caactccccg ataaggaatg aggaacttac
    29041 tactaatcac tgctaggtca gctaaacagg attcttgacc gtctgcaaca cgaacatttt
    29101 gcatctgatc ctcacgcaac ccctcacgaa tctccaaggc caccttttgc ggttggtcaa
    29161 agaactgata ggctgctaga ttggcaaaat tcaagagatt aaccttgcca gccaccacaa
    29221 tgttttcgtt gaacatttcc ttaaagatgt gttcaaagag atcaatcaca ttatccgttg
    29281 ttgtaaagta acgctggata atctgcggaa tctccgtccg aatcttgtag tgaatatcta
    29341 aaacagtgtg accgaggaaa cgttcctgaa tgattgcctt cagtttcagc aaatcctcct
    29401 gcaagaagtt ccttggaatc agaaactgac tagtaaccgt tcgcgactcg tctagggtaa
    29461 ataccgccaa ggctgtatgt tgccccaaaa caacgatatc aaaggctgtc aaccgttgcc
    29521 tgctcggctc aacatccagt gccactaccg tacagccact caggtctgtt agcaagttag
    29581 cagcctcttg cagaatatcc tccaatttga agaattcctg atcaaaggct ttgacaatct
    29641 catatacctc attttcagcc agccggtcaa aatccagtga gtgtttcaca tagtactgaa
    29701 aaccagcaac acttggcatc cgaccgcttg aagtatgagc cttctcaagc aacccttgtt
    29761 tttctagttc cgccatgtca ttacgaatgg ttgcactgct agagttaata gactcttgca
    29821 aggcttttga tccgacaggt tcgtgcgttt tggtaaagat gtcaataatc agatttaaaa
    29881 tatcctgctg acgctctgta accatctcat cactcctctc tgtctgatca attagcactc
    29941 aaggcatcca agtgctaact tatgattcta ttatacaccc ttagaagaga atgtcaagac
    30001 aaaaactcaa aaaattagca ctcttttatc aagagtgcta aaaatcaatc tgaagaccta
    30061 gaaccttgct attcatctac tcggtatttc ctttttagtc tgaaataacc atgaattaga
    30121 taagaaatca gaaaagcata taaaacaaaa ataagaaaga aagacataga aagatcttct
    30181 ctaaacgaac tcatacaaac aacaagacca cctaagaaag tagctgtaca ggaacgaagt
    30241 ctagatcgca taacttccca tttgagcccc ttactcatat agacttgatc ctctggaagt
    30301 aaatcagaag acgatttacg aagaatcgaa caagaacctg ctcctatcaa ttcccaacct
    30361 ctatctctaa aatcttgcag ttcatgctta tattttttaa gaaatctaga atcatagata
    30421 cggtagatga catcgtctgg ttgaccttgc tcaaaataga acaaaccaaa acaactagtt
    30481 ctatacctcc aacctttcaa atgcatctca tgtaaatact cttcttcctt atccaaatca
    30541 acaatggtga aaatccgaaa ttctactctg ctattcattg tcctacccca aaattagaaa
    30601 acatgcctgg cgttatttat tagataattc tttccacttt tgactcaatc tccaaaaaat
    30661 ataagaaatc tgaatcgcaa aaactatcaa taaaacccaa tctattatga aaatcaaaaa
    30721 tactccccaa ctgaaagaac tacctccagt gacaaacttt gagaaaaccg gtaatagagc
    30781 taaaaagaga agcaaaatag gaagcatccg cattgttaaa atccgtttgg cataaaaaaa
    30841 tctttattta aacgaaaata ttatggcaaa atttacgcca gtttttgaac ggctgatgta
    30901 gatattttat actttcaaaa tgtttaaatg tgattattta tttttgaaaa atagctcacc
    30961 agcccgactg aaagtgctta tagaatgata ataagtcgcc tgccgaaaac agcgaaaaat
    31021 agcggtgtta tgcggagata atctgacgcg atgcgaaagt atattgcata cttattttca
    31081 acaatttagc agagtatttt tataagtgtg atataataga agtataattt gttctgatag
    31141 tttattttat ggagaagtag atttttagaa tgcggagggt tcaatatggt tgagtttata
    31201 aagtctaaga aagaaatgag tgaggaggat attaaagcaa atttcatcac tcctgctatt
    31261 gtatccaaag gatggaaaag tggtgagcat atcacttacg aagaatactt cactgatggt
    31321 cgaattgagg ttagaggaga taaggctcgt cgtaaagaag gaaaaaaatc agactattca
    31381 ctgtattacc aatttggaac tcgaattgca attgttgagg caaaggataa taaacacagc
    31441 gttcgagcag gattacaaca agctattgaa tatggagaga ttttagatgt tccatttgtt
    31501 tattcttcga atggtgatgg ctttattgaa cacgaccgta tcacgagaga agaacgtgag
    31561 ctggagttag acgaattccc tactcgtgaa gaattatttt ctcgtatgac gaaggaaaaa
    31621 ggattgacgt acgaaattac agaagctatc tcaactccat actatacaga cgccttctca
    31681 atgaaaacgc cacgctatta tcagcaaata gctatcaacc gtactattga aacagttgcc
    31741 agaggacaaa aacgagtaat gtttgtgatg gcaacaggaa cggggaaaac gttcatggct
    31801 tttcaaatta ttcatcgcct tcgaaaagct ggtttggcta aacgagtttt attcttagca
    31861 gatagaaaca tcttagtaga ccaaacgatg gctgaagact ttaggccatt cgaaaaggta
    31921 atgacgaaaa ttacaccaaa acttttgact gctcctgaaa aattaaattc ttttgaaatt
    31981 tatctagggc tttatcagca actaactggt gaagatggaa ctgaaacaca ttatcaaaaa
    32041 tttgacaaag acttctttga tttaatcgta attgatgaag cgcaccgtgg ttcagctaag
    32101 gaagacagta actggcgtaa ggtgattgat tatttcagtt ctgcgacaca gattgggatg
    32161 accgctactc ctaaagaaac caagaatgct tccaatacgg aatactttgg tgagccaatc
    32221 tatacttata gtttaaaaca gggaatcgag gatggttttt tggctccata tcgtgttatg
    32281 agggttaatt tagatgtgga tgtggatggt tatcgtccag aaactggaaa agttgatgct
    32341 aacggacaat taataggaga taggtactac ggcaggaaag attttgataa aaccattgtc
    32401 attgatgata gaacgcaaag agttgccaag tttgtttctg attatatgaa gcaaaacaat
    32461 gcacgatttg ataaaacaat tgttttttgt gttgatattg accatgccga gcgaatgcgt
    32521 gctgcacttg taaaagagaa tctagactta gtccaagaag actatcgtta tgtcatgcaa
    32581 gtaactggtg acaacgctga aggaaaagct caactggata actttatgga tgtcaattct
    32641 aattttcccg ctatggtaac aacgtctaaa ttattaacga caggagttaa tgctaaaaca
    32701 tgtcgtttga ttgttttaga ctctaatatc caatccatga ctgaatttaa acaaattatt
    32761 ggtcgtggca cacgtcttta tcctcaaaag gggaaagaat tttttacgat tattgatttt
    32821 cgaaatgtta ccaatctgtt tgctgaccct gattttgatg gtgagccagt gaaggtgctg
    32881 gaaacaggtg cgaaaacagt cagtggttct acgcctggtt tcgtaggtga ggaaggtgac
    32941 ccagtagaaa aatatatcgt tacagacaag caggttacca ttcttaattc tactgttcaa
    33001 gtattggatg aaaacgggaa actgattacc gaaagcctga ccgactacac tcgaaagaat
    33061 atcttaggta gctacgccac tttgaacgat tttatcacag tttggcatac ggcagataaa
    33121 aagaagctta tcttagacga actttataaa aaaggagttt atctagatgc tattcgagag
    33181 tcggagggaa tatcagaaca agaaatcgat gattttgatt tactcctaaa acttgcctat
    33241 ggtcaaaaag aattaaccaa aacggaacgt atcaataaac tcaaacaaag cggatattta
    33301 tataaatata gtgaggaagc gcgtgctgtt ttggaaattt tactggacaa atacatggat
    33361 aaaggtattg gagaactcga aagcattgaa acattaaaac ttccagaatt tcagatatat
    33421 ggtggaacct tcaaaatcat caatacttat tttggagata aaaaacgata tttacaagca
    33481 attaaagaat tggagcaaga gctatttaca gtagcttaat gaaaggaaag tatgtcaatt
    33541 acatcatttg taaaaagaat tcaagatatc actcgaaacg atgctggtgt taatggtgat
    33601 gctcaacgta ttgagcaaat gtcttggtta ttattcttaa aaatttatga tagccgtgaa
    33661 atggtttggg aattagaaga agacgagtat gagtcaatta tcccagagga attaaaatgg
    33721 cgaaattggg ctcatgctca aaatggggaa cgggtattga caggcgatga attacttgat
    33781 tttgtcaata acaagttatt caaagagttg aaagagcttg aaataacttc aaatatgcct
    33841 attcgaaaaa cgattgttaa atcagctttt gaagatgcga acaactatat gaaaaatggc
    33901 gtcttgttac gccaagtcat caatgttatt gatgaagttg atttcaacag ccctgaagat
    33961 cgtcattcgt ttaatgatat ttacgaaaaa attcttaaag atattcaaaa tgctgggaac
    34021 tcaggagaat tttatacgcc acgtgcagcg actgatttta ttgccgaagt tcttgaccca
    34081 aaacttggag aatcaatggc agaccttgct tgcggaacag gaggcttctt gacttcgact
    34141 ctgaaccgtt taagtagtca acgtaaaact agtgaagata caaaaaaata taatacagct
    34201 gtttttggta ttgaaaagaa agcatttcct catcttttag cagttacaaa tctgtttctt
    34261 cacgaaattg atgaccctaa aattgttcat ggaaatactt tggagaaaaa tgttcgtgaa
    34321 tatacggatg atgaaaaatt tgacattatt atgatgaatc caccttttgg agggtcagaa
    34381 ttagaaacaa taaaaaataa ctttccagca gaattacgga gttctgaaac ggctgattta
    34441 tttatggctg tcattatgta tcgtttgaaa gaaaatggtc gtgttggagt tattttacct
    34501 gatggttttc tatttggtga aggtgtaaaa actcgcttga aacaaaaact ggtagatgag
    34561 ttcaacttgc atacgattat taggttgcct catagtgtct ttgcaccgta tacaggaatc
    34621 catacgaaca ttcttttctt tgataaaaca aagaaaacag aagaaacttg gttttatcgt
    34681 ttagatatgc cagatggtta taaaaatttc tctaaaacta agccgatgaa gtcagaacac
    34741 ttcaatcctg ttcgtgactg gtgggaaaat cgtgaagaga ttctggaagg taagttctac
    34801 aaatctaaat catttacacc tagtgaattg gctgagttga attataattt agaccagtgt
    34861 ggttttccaa aagaggaaga ggaaatctta aatccctttg agttgattca gaattatcaa
    34921 gcggaaagag cggctttaaa tcataaaatt gataatgtat tagctgatat tttgcagttg
    34981 ttggaggata aataatgaca ccagaacaac ttaaagcaag tatccttcaa agagcgatgg
    35041 aagggaaatt agtgccgcaa aatcccaatg acgaacctgc aagtgaattg ttaaagagaa
    35101 ttaaagctga aaaagaaaaa cttatcagtg aaggaaaaat caaacgagat aaaaaggaaa
    35161 ccgagatatt tcgtggtgat gatgggaaac attatgggaa gtttgctgat ggaagcactc
    35221 aagaaattga tgttccttat gatattcctg atacttggga gtgggtgagg ttttctacat
    35281 tggttgaaat tgtcagaggt ggctctccac gaccaatcaa agattatctt acttctgaag
    35341 tagatggaat aaattggata aaaataggtg atactgaaaa gggtgaaaag tatataaata
    35401 atgttaaaga aaaaatcaaa aaatcagggc ttaacaaaac tagatttgta aaaaaaggta
    35461 catttttgtt aactaattct atgagttttg gtagacctta tattttgaat gttgatggtg
    35521 caatacacga tggatggttg gctatttcga actatgaaaa ctcattaaat aaagattacc
    35581 tattctatat tctttcatca aatgtagttt attctcaatt tctatctcta attagtggag
    35641 ctgttgtgaa aaacttgaat agtgataaag ttgcttctat tcttatccct ctccccccac
    35701 tatccgaaca acaacgcata
//
LOCUS       DAVDZK010000022        34380 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVDZK010000022 DAVDZK010000000
VERSION     DAVDZK010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34380
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.023"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            105..560
                     /locus_tag="VUX16_001238"
                     /pseudo
     CDS             105..560
                     /locus_tag="VUX16_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            713..1009
                     /locus_tag="VUX16_001239"
     CDS             713..1009
                     /locus_tag="VUX16_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET8124205.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYK"
     gene            1215..2960
                     /locus_tag="VUX16_001240"
     CDS             1215..2960
                     /locus_tag="VUX16_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124206.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            2950..4701
                     /locus_tag="VUX16_001241"
     CDS             2950..4701
                     /locus_tag="VUX16_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124207.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMADTL"
     gene            4874..5566
                     /locus_tag="VUX16_001242"
     CDS             4874..5566
                     /locus_tag="VUX16_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET8124208.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLAFVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            5609..6835
                     /locus_tag="VUX16_001243"
     CDS             5609..6835
                     /locus_tag="VUX16_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET8124209.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKIVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            7966..10125
                     /gene="pfbA"
                     /locus_tag="VUX16_001244"
     CDS             7966..10125
                     /gene="pfbA"
                     /locus_tag="VUX16_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET8124210.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNYKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGREAENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            10653..10967
                     /locus_tag="VUX16_001245"
                     /pseudo
     CDS             10653..10967
                     /locus_tag="VUX16_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            11147..11806
                     /locus_tag="VUX16_001246"
     CDS             11147..11806
                     /locus_tag="VUX16_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET8124211.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRVTEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVRFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVSYHEKF
                     K"
     gene            11831..12898
                     /locus_tag="VUX16_001247"
     CDS             11831..12898
                     /locus_tag="VUX16_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET8124212.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDAKEMPKDWT
                     ELASKYKGQYSIYGLTGGTGRAIYASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALVGQKEQNVVFKVMSPEIGVPFVTEQTMILS
                     TSKKQALAKEFIDWFGQSEIQVEYSKNFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            13001..14011
                     /locus_tag="VUX16_001248"
     CDS             13001..14011
                     /locus_tag="VUX16_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124213.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSKSQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            14023..15714
                     /locus_tag="VUX16_001249"
     CDS             14023..15714
                     /locus_tag="VUX16_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET8124214.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            15717..16427
                     /locus_tag="VUX16_001250"
     CDS             15717..16427
                     /locus_tag="VUX16_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET8124215.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            16523..16891
                     /locus_tag="VUX16_001251"
     CDS             16523..16891
                     /locus_tag="VUX16_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124216.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            16999..18000
                     /locus_tag="VUX16_001252"
     CDS             16999..18000
                     /locus_tag="VUX16_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET8124217.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    18212..18441
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            18601..18681
                     /locus_tag="VUX16_001253"
                     /pseudo
     CDS             18601..18681
                     /locus_tag="VUX16_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            18670..18813
                     /locus_tag="VUX16_001254"
     CDS             18670..18813
                     /locus_tag="VUX16_001254"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124218.1"
                     /translation="MDRTDEVSSKHCFEVADRTDEVSNHTYDKATLTRFEEFFEEYKG
                     VPR"
     misc_binding    18882..19113
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            19185..20546
                     /gene="trpE"
                     /locus_tag="VUX16_001255"
     CDS             19185..20546
                     /gene="trpE"
                     /locus_tag="VUX16_001255"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET8124219.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDLLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEVLEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVINPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELIAMDALKSTLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            20543..21109
                     /locus_tag="VUX16_001256"
     CDS             20543..21109
                     /locus_tag="VUX16_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET8124220.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            21120..22124
                     /gene="trpD"
                     /locus_tag="VUX16_001257"
     CDS             21120..22124
                     /gene="trpD"
                     /locus_tag="VUX16_001257"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET8124221.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            22121..22888
                     /gene="trpC"
                     /locus_tag="VUX16_001258"
     CDS             22121..22888
                     /gene="trpC"
                     /locus_tag="VUX16_001258"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET8124222.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALAEERLKELYDYATVLGLEVLV
                     ETHNLAELEVAHRLGAQIIGVNNRNLTTFEVDLQTSVDLAKHFKDDCLYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            22875..23474
                     /locus_tag="VUX16_001259"
     CDS             22875..23474
                     /locus_tag="VUX16_001259"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET8124223.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPSGVKKVGVFVSPSRVELLEVIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            23452..24675
                     /gene="trpB"
                     /locus_tag="VUX16_001260"
     CDS             23452..24675
                     /gene="trpB"
                     /locus_tag="VUX16_001260"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET8124224.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            24668..25444
                     /locus_tag="VUX16_001261"
     CDS             24668..25444
                     /locus_tag="VUX16_001261"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET8124225.1"
                     /translation="MPKTLTEKLNAIKATGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVKPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(25416..25517)
                     /locus_tag="VUX16_001262"
                     /pseudo
     CDS             complement(25416..25517)
                     /locus_tag="VUX16_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            25951..26505
                     /locus_tag="VUX16_001263"
     CDS             25951..26505
                     /locus_tag="VUX16_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124226.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIIYVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            26520..27671
                     /locus_tag="VUX16_001264"
     CDS             26520..27671
                     /locus_tag="VUX16_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET8124227.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(27723..28382)
                     /locus_tag="VUX16_001265"
     CDS             complement(27723..28382)
                     /locus_tag="VUX16_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET8124228.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNHFRCRYCKVRYPVWYALFELGLGLIFLLYSWGWLSLGQVILITAG
                     LTLGIYDFRHQEYPLLVWMTFHLILIAYSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASAMGILSFILQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            28452..28907
                     /locus_tag="VUX16_001266"
     CDS             28452..28907
                     /locus_tag="VUX16_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124229.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALQDLEGVFSIFDEQEFVELIHKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSL
                     AFENEDIDSISLNVLEANQRAQNLYQKEGFEIVQMVEAPVRKYIMKKGR"
     gene            28947..29219
                     /locus_tag="VUX16_001267"
                     /pseudo
     CDS             28947..29219
                     /locus_tag="VUX16_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(29329..29532)
                     /locus_tag="VUX16_001268"
     CDS             complement(29329..29532)
                     /locus_tag="VUX16_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET8124230.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGVAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(29563..30171)
                     /locus_tag="VUX16_001269"
     CDS             complement(29563..30171)
                     /locus_tag="VUX16_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET8124231.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEVVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(30202..30372)
                     /locus_tag="VUX16_001270"
     CDS             complement(30202..30372)
                     /locus_tag="VUX16_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET8124232.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(30384..30950)
                     /gene="amaP"
                     /locus_tag="VUX16_001271"
     CDS             complement(30384..30950)
                     /gene="amaP"
                     /locus_tag="VUX16_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET8124233.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIQLLSWRQNS
                     AVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVLDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIVDRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(31034..31231)
                     /locus_tag="VUX16_001272"
     CDS             complement(31034..31231)
                     /locus_tag="VUX16_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET8124234.1"
                     /translation="MAGKITKKGSSMGNIANVFAGLIGASAGQSLLGSWGPSIAGMAL
                     LPFIVGAAIMITVVSFFTGRK"
     gene            31647..33119
                     /locus_tag="VUX16_001273"
     CDS             31647..33119
                     /locus_tag="VUX16_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET8124235.1"
                     /translation="MRDLLSKKSHRQLELLFEHKRWFHRSELAELLNCTERAVKDDLS
                     HVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFSEGCQAES
                     ICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQVIGNERDIRYFFAQYFSEKYY
                     FLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDK
                     DSFNDQSLNALMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDGSLFMK
                     CVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELSTEFILF
                     DQKGNTIRNFQNIFPKFVSDVKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVIN
                     LLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSPYDI
                     IISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            33435..>34380
                     /locus_tag="VUX16_001274"
     CDS             33435..>34380
                     /locus_tag="VUX16_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET8124236.1"
                     /translation="MEQLHFITKLLDIKDPNIQFMDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKTSMTDIAHQLAISTSTVIRKLNDFHFECKVRNLPEIMSWDEYA
                     FTKGKMSFIAQDFEKLNIITVLEGRTQAVIRDHFLKYDRAVRCQVKIITMDMFSPYYA
                     LAKQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKLLSYSEDLKHHYQL"
BASE COUNT        10919 a         5871 c         7011 g        10579 t
ORIGIN      
        1 ttttattata ccaaaaaaag atctatttcc ccaacgtata gtttgaaaaa ttactctctt
       61 tcgtttataa ttaagaatga ttttatgaaa gggagtgaaa acacatgaaa ttctactctt
      121 atgactatgt actcagccaa atcggtcagc aaaatggtat catggttggc tttgggattg
      181 ttctattagc tgtgacagtt tttttgcttt taaggtatac catgataaaa agggaaccga
      241 atttcgtgag ttggtcatga tttcagctct ggccttattt agctctgctt ttggtcagca
      301 tcacgactta tcaaaacaat caagtttcta acaataaatt tcaaacttca cttcatttca
      361 tcgaggttgt ttccaaagat ttgggagtag acaagtcaga agtctatgtt aatacttcca
      421 caaacacaga tggcgcactt atcaaggtgg gagaacgcta ttatcgtgcc ctaaacggaa
      481 gtgagccaga caagtacctg ttagagaaag tcgaattgta taagacagac gcaattgaac
      541 tggtggatgt gaacaaatga cacttaatta tatcgaaatt ttaatcaaac tggtcttgac
      601 tctcaaatag ctcaacaaca atgttcactt tgtgaaacgt ttgattgatg gtaagccaac
      661 tctccttatc aaaaatggga atattgaccc ataagcctgt cgttcagttg gtttgtctgc
      721 atcggatgta gccctcaaac ttcgtagcca agggattttc cagatgaagc aagtcaaacg
      781 agctgtgcaa gagcaaaatg ggcaactcat cgttgtgcaa atgggagatg aaaatcctaa
      841 gtatccagtt gtgactgacg gtgtgattca agtagatgtc ttggaatcga ttggtcgtag
      901 cgaagagtgg ttgcttgata acctcagtaa acaagggcat gacaatgtag ccaatatctt
      961 tattgctgaa tatgacaagg gtgctgttac agtcgtaact tataaataag aaaaacctgg
     1021 ggtcttgtac tcttcgaaaa tctcttcaaa ccgcgtcaac gtcgccttgc cgtatgtagg
     1081 ttactgactt cgtcagttct atctacaacc tcaaagcagt gctttgagca gcctgcggct
     1141 agtttcctag tttgctcttt gattttcatt gagtattggc ctcaggtttc catttgcaat
     1201 cagaaaggga ttttatgtcc attattcaaa aactctggtg gtttttcaag ttagaaaaac
     1261 gccgttatct agtcgggatt gtggccctgg tcttggtttc cgtcctcaat ctcattcctc
     1321 ctatggttat ggggcgagtc attgatgcca tcacatcggg gcaattaact cagcaggacc
     1381 tccttcttag cctattttac ttgctacttg cagcctttgg tatgtactat ttgcgctatg
     1441 tgtggcgtat gtatatcctt gggacctctt attgcttggg acagatcatg cggtctcgct
     1501 tgtttaagca tttcacaaaa atgtcatcag ccttttatca aacctatcgg acgggtgatc
     1561 tgatggcaca cgcaaccaat gatatcaatg ccttgactcg tttagcaggt ggcggtgtca
     1621 tgtctgcggt ggatgcctct atcacggctc tggtgacttt gttgaccatg ctctttagca
     1681 tctcatggca gatgactctt gttgccattc tccccctacc tttcatggcc tatgcgacta
     1741 gtcgcctagg gagaaagact cataaggcct ttggcgaatc ccaagctgct ttttctgaac
     1801 tcaataacaa ggtacaggag tccgtatcag gtatcaaagt gaccaagtct ttcggttatc
     1861 aggcagacga gttgaagtct tttcaggcag tcaatgaatt aaccttccaa aagaacctgc
     1921 aaaccatgaa atatgatagt ctctttgacc ctatggttct cgtgtttgtt ggttcgtcct
     1981 atgttttaac gcttttggtt ggctccttga tggttcagga agggcagatt acagttggga
     2041 atctagtcac ctttatcagc tatttggata tgctggtctg gcctcttatg gccatcggct
     2101 tcctctttaa tactactcag cgagggaagg tttcttacca gcggattgaa aatcttttgt
     2161 ctcaggaatc tcctgtacaa gaccctgagt ttcctctgga tggtattgaa aatgggcgtt
     2221 tggagtatgc cattgacagc tttgcttttg aaaatgagga aacactgacg gatattcact
     2281 ttagtttggc aaaagggcaa acactgggct tggttgggca gacaggctct gggaaaacgt
     2341 ccttaatcaa gctcctcttg cgtgaatacg atgtggataa gggtgccatt tatctaaacg
     2401 gtcacgatat tcgggactat cgtctgacag accttcgcag tctcatgggc tatgttcctc
     2461 aggaccagtt tctttttgcg acttcaatcc tagacaatat ccgctttggc aatcctaact
     2521 tgcccctttc agcggtcgag gaagctacta agctagcccg ggtttaccaa gatattgtag
     2581 acatgcctca aggatttgat acgctgattg gtgaaaaagg agtcagtctt tctggtggtc
     2641 aaaagcaacg gttggctatg agtcgggcta tgattttaga ccctgatatc ttgattttgg
     2701 atgattcctt atccgccgta gatgccaaga cagagtatgc gattatcgac aacctcaagg
     2761 agacgcgaaa ggacaagaca accattatca ctgcccatcg cctcagtgct gttgtccatg
     2821 cagattttat tttagttcta caaaatggtc aaattatcga acgaggcacg cacgaagact
     2881 tgctagcgat ggatggctgg tatgcccaaa cctaccagtc tcagcagttg gaaatgaaag
     2941 gagaagaaga tgcagaataa acaagaacaa tgggctgtat tgaagcgctt gatgtcttat
     3001 ctcaagcctt atggactcct gacctttttg gcactcagtt ttctcctagc gacgacggtc
     3061 attaaaagtg tcatacccct cgtggcttcc cactttatcg accagtatct cagcaatctt
     3121 aaccaactag ccgttaccgt tttgctggtc tactatggtc tctacatcct acaaactgta
     3181 gttcagtatg tgggcaatct tctctttgcg cgcgtgtctt atagtattgt tagggatatt
     3241 cgtcgagatg cctttgctaa tatggagaaa ctgggcatgt cttactttga caagacgcca
     3301 gcaggttcta tcgtttctcg tttgaccaac gataccgaga cgattagtga tatgttttct
     3361 gggattttat ccagctttat ctcagcagtt tttatctttc tgacaaccct ttataccatg
     3421 ttggtgctgg attttcgttt gacggcttta gtcttgctct ttcttccttt gattttcctt
     3481 ttggtcaatc tctatcgaaa aaagtcagtg aaaatcatcg agaaaaccag aagtctcttg
     3541 tcagatatca atagtaagct ggcagagaat atcgagggaa tcaggattat tcaggctttt
     3601 aatcaagaga agcgcctgca ggcagaattt gatgaaatca accaagagca cttggcctat
     3661 gccaaccgtt ctgtagcctt ggatgccctc tttttgagac ctgccatgag tttgttgaaa
     3721 cttctaggtt atgctgtctt gatgacctat tttggctatc gtggtctttc tatcgggata
     3781 acggccggga ccatgtatgc ttttatccag tacatcaacc gcctctttga ccctttgatt
     3841 gaggtgacgc aaaacttttc aacactgcaa acgtctatgg tttctgcagg ccgtgtcttt
     3901 gccttaatcg atgagaggac ctatgagcct cttcaagaaa atgggcaagc caaagtcaaa
     3961 gaaggcaata tccgttttga acatgtgtgt ttctcgtatg acggtaaaca tccgattctg
     4021 gatgacattt ctttctctgt taataagggt gaaaccattg cctttgtagg tcatacaggt
     4081 tcagggaaat cgtctattat caatgtcctc atgcgctttt atgaattcca gtcagggaga
     4141 gttctcttgg atgatgtgga tatcagggat ttcagtcaag aagagctgag aaaaaacatc
     4201 ggtttggttt tacaggaacc cttcctctat catggaacta ttaagtccaa tatcgccatg
     4261 taccaagaaa tcagtgatga gcaggttcag gctgcggcag cctttgtgga tgcagattcc
     4321 tttattcaag aacttcctca ggggtacgac tcccctgttt ccgagcgtgg ttcgagcttc
     4381 tctactgggc aacgccagct ccttgccttt gctagaacag tcgccagcca gcctaaaatc
     4441 ctgattttgg atgaagcgac agccaatatt gactctgaaa cagaaagctt ggttcaagct
     4501 tctctggcga agatgagaca gggccgaaca actattgcta tcgctcaccg cctttctact
     4561 attcaagacg ccaactgcat ctatgtcttg gataagggac gcattatcga gagtggaacc
     4621 catgaggaac tcttgactct gggaggaacc tatcacaaga tgtatagttt gcaggcaggg
     4681 gccatggccg atactctttg aaaatctctt taaaccatgt cagctttatc tgcaatctca
     4741 aagctgtact ttgattttca ttgagtacta gaaggaaatc cttcaaatta cagatttctt
     4801 tcaccgcctt ttccattttg tggtataatg aaaaatgttg acaaatagta taataaaaac
     4861 aaaggagaac agcatgctga aatgggaaga cttgcctgtg gaaatgaaat caagcgaggt
     4921 tgagtcttat taccagcttg tctctaaaag gaagggttcg ctgattttca agcgttgctt
     4981 ggactgggtt ctagcctttg tcttactggt tctgacctct cccatctttc tcatcttgag
     5041 catttggatc aagttggata gcaaggggcc agtgatttac aagcaagagc gtgtgaccca
     5101 gtacaaccgt cggttcaaga tttggaagtt ccgtaccatg gtgacggatg cggataaaaa
     5161 aggaagtctg gtgacttctg ctaacgatag ccgtattacc aaggttggaa atttcatccg
     5221 acgtgtccgt ttggacgaac tgcctcagtt ggtcaatgtc cttaaaggtg agatgtcctt
     5281 tgtcggtaca cgacctgaag tgccacgtta tacagagcag tatagccctg aaatgatggc
     5341 aaccttgctc ttgcaagcag gaattacctc tccagccagc atcaactaca aggatgagga
     5401 caccatcatc agtcaaatga cggagaaagg tctgtcagtt gatcaggcct atgtggagca
     5461 tgttcttcct gaaaagatgc gctataacct cgcctatctc cgagagttta gtttctttgg
     5521 ggacatcaaa atcatgtttc aaaccgtgtt tgaggtacta aaataaagta gtcataagaa
     5581 aatgagtaca gataaaagga gcaaatcaat gccaaattac aatattccat tttcaccgcc
     5641 tgatatcaca gaagcagaaa ttgctgaagt agcggatacc ctgcgttctg gttggatcac
     5701 aacaggtcct aaaacaaaag aactggagcg ccgcttgtct ctttacacac agacacctaa
     5761 gattgtttgt ctcaactctg cgacagctgc tctggagttg attttacgcg ttttggaagt
     5821 gggacctggt gatgaagtca tcgttccagc catgacctat acggcttcat gtagtgtcat
     5881 tacgcacgtg ggagcaaccc ctgtcatggt ggatatccaa gcagatacgt ttgagatgga
     5941 ctatgacctg cttgagcaag ctatcactga gaaaactaag gtgattatcc cagtagagct
     6001 cgcagggatt gtttgcgatt atgaccgttt gttccaagtc gtggagaaaa aacgtgactt
     6061 ctttaccgct tcaagcaagt ggcaaaaggc ctttaaccgt attgtcattg tctctgatag
     6121 tgcccacgct ttgggatcta cttataaagg acaaccttct ggttctatcg ctgactttac
     6181 ttccttctca ttccatgccg ttaagaactt tacaacggca gaaggtggaa gtgcgacttg
     6241 gaaagccaat ccagtgattg atgacgaaga gatgtacaag gaattccaaa tcctttccct
     6301 tcacgggcaa actaaggatg ctcttgccaa gatgcaactg gggtcatggg aatacgatat
     6361 cgttacacca gcctataagt gcaacatgac cgatatcatg gcttcacttg gtttggtaca
     6421 attggaccgc tatccaagtt tgttacaacg ccgtaaggac attgtggacc gctatgatag
     6481 tggttttgca ggttctcgca tccatccttt ggcacacaag actgaaactg tcgaatcttc
     6541 acgccacctc tacatcaccc gtgtagaagg agcaagccta gaagaacgca acctcatcat
     6601 ccaagaattg gctaaagcag gaattgcaag taatgttcac tacaaaccgc ttcctctctt
     6661 gacagcctat aagaatcttg gatttgatat gacgaactat cctaaggcct atgccttctt
     6721 tgagaatgaa attaccctcc ctcttcatac taaattaagc gatgaagaag tagactatat
     6781 cattgagact ttcaaaacag tttctgaaaa agtgctaact ttatcaaaaa aatgacaaac
     6841 tacagtcaag cgaaagtgat cctgtcctta aaaagtctaa ttgagtgtaa aaactgttgt
     6901 tttcaattga taatagttta cacctgtagt tgaggctcct ttctcctcag agagagaatt
     6961 tttataggat tttcctttct tgtgggagtc ccgtggtttg aaataagatg tgagcaattt
     7021 ggtgtagcat ttagaatcct tactagacat catttagaaa atctagtgtc ttgttctagt
     7081 tttcaattca ccctattttt tgaaagacgt gagtttccat gagtgagatt gtggaaactc
     7141 gcgtcttttt tttgttttca gaatattgtt caaagttttg tgcctgtctt tcatgttcta
     7201 gtcattcttt tacatgatag aatttatagc atgttgatat tataataata cgaatatccc
     7261 atatgtttag tgatgcttgc tatacatcat tagatctcct gcgagacaat ctataaaaca
     7321 cttgtctacg attacctata tgccctattc cagtatttta gaagcactgc atctattttt
     7381 atcgaggtta aatctagctt ttatagaagg tctatttaag aaatatattg tagtgtttta
     7441 gtttcaatcc gccatatgag cgatattaag gtaaatatcc ctggcgaatg cttgtatgac
     7501 aaggtatttg ttctttcatt tataatttac aacatatcaa taaatttaaa tatagtaaat
     7561 gggatatttt atattcaagc taagaaagat agcatcactt ttgaatggaa ggctaaagag
     7621 caaactagga agttggccat agatagctca aaaccctgct ttgaggttgt agatatagta
     7681 aaaggaaata agaataggac aaatcgatcg ggacagtcaa atcgatttct aacaatgttt
     7741 tagaagtaga ggtgtactat tatagtttca gtctactata gaactgacca agtcagtaac
     7801 ctagacttag ggcaaggcgg cactgaccta gtttgaagag atttccgaag agtataaatt
     7861 ttaatatttt cttgtgttat tccttgacaa ttcaatttgg aaaatatatg ataaagataa
     7921 tgacagcggt gtcattctat ctattttaag aaaagtaata atcaattgtt aaaaatagta
     7981 aaaaaattgg aggttctgat gaaatatttt gttcctaatg aggtattcag tattcgtaaa
     8041 ttaaaggtgg ggacttgctc ggtactattg gcaatttcaa ttttgggaag ccaaggtatt
     8101 ttatcggatg aagttgttac tagttcttca ccgatggcta caaaagagtc ttctaatgca
     8161 attactaatg atttagataa ttcaccaact gttaatcaga atcgttctgc tgaaatgatt
     8221 gcctctaatt caaccactaa tggtttagat aattcgttaa gtgttaatag catcagctct
     8281 aatggtacta ttcgttccaa ttcacaatta gacaacagaa cagttgaatc tacagtaaca
     8341 tctactaatg aaaataagag ttataaggaa gatgttataa gtgacagaat tatcaaaaaa
     8401 gaatttgaag atactgcttt aagtgtaaaa gattatggtg cagtaggtga tgggattcat
     8461 gatgatcgac aagcaattca agatgcaata gatgctgcag ctcaagggct aggtggagga
     8521 aatgtatatt ttcctgaagg aacttattta gtaaaagaaa ttgttttttt aaaaagtcat
     8581 acacacttag aattgaatga gaaagctaca attctaaatg gtataaatat taagaatcac
     8641 ccttccattg tttttatgac aggtttattt acggatgatg gtgcgcaagt agaatggggc
     8701 ccaacagaag atattagtta ttctggtggt acgattgata tgaacggtgc tttgaatgaa
     8761 gaaggaacta aagcaaaaaa tctaccactt ataaattctt caggtgcatt tgctattggg
     8821 aattcaaata acgtaactat aaaaaatgta acattcaagg atagttatca agggcatgct
     8881 attcaaattg caggttcgaa aaatgtatta gttgataatt ctcgttttct tgggcaagcc
     8941 ttacccaaaa cgatgaagga tgggcaaatc ataagtaagg agagcattca gattgaacca
     9001 ttaactagaa aaggttttcc ttatgccttg aatgatgatg ggaaaaaatc tgaaaatgtg
     9061 actattcaaa attcctattt tggcaaaagt gataaatctg gggaattagt aacagcaatt
     9121 ggcacacact atcaaacatt gtcgacacag aacccctcta atattaaaat tttaaataat
     9181 cattttgata acatgatgta tgcaggtgta cgttttacag gattcactga tgtattaatc
     9241 aaaggaaatc gctttgataa gaaagttaaa ggagagagtg tacattatcg agaaagcgga
     9301 gcagctttag taaatgctta tagctataaa aacactaaag acctattaga tttaaataaa
     9361 caggtggtta tcgccgaaaa tatatttaat attgccgatc ctaaaacaaa agcgatacga
     9421 gttgcaaaag atagtgcaga atatttagga aaagtatcag atattactgt aacaaaaaat
     9481 gtaattaata ataattataa ggaaacagaa caaccaaata ttgaattatt acgagttagt
     9541 gataatttag tagtctcaga gaatagtata ttcggtggta aagaaggaat tgttattgag
     9601 gattcaaagg gtaaaataac cgttttaaat aaccaatttt ataatttatc cggtaagtat
     9661 atatcattca tcaaatctaa tgcaaatggg aaagaacctg ttatacgtga tagcgatggt
     9721 aatttcaata ttgtaacgga gaatgggctt tacaaaattg taacaaataa tttaagtgat
     9781 aaaaacgaaa aagaaaaaaa caaagaggaa aaacaatcta attcaaataa tgtaattgat
     9841 agtaaccaga agaacggaga gtttaactca agtaaagata atagacaaat gaatgacaag
     9901 atcgacaata aacaagataa taagacagaa gaagtaaact ataaaatagt tggagatggc
     9961 agagaagctg aaaatcatat taataaatct aaagaaatag tagatgtaaa acaaaaatta
    10021 ccaaagactg gttcgaacaa gattatggaa ctattcttaa cagtgacagg aattggttta
    10081 cttttgacac taaaagggtt gaagtattat ggtaaagata aataaaattt gttcgattac
    10141 aaggaagttc cgtagaaaat gaggatattg taggttcaca aaatcagtat ttttggatta
    10201 ttggtggagc tacagattta tataattcta aagaggagat aggttattca gtctcagaag
    10261 ttgtacatat tttatcagaa agtttgtcgg ttaattgtaa agaatcaaaa actcttaaac
    10321 aaatatttga aactgcttta ctcgaggtta aagatgaaat cggtttaaac tcatatgaat
    10381 taacagagta tagtaaaatg aaataataat aggacaaatc aatcaggaca gtcaaatcta
    10441 tttttaacaa tgttttagaa gtaggggtgt actattctag tttcaatcta ctatattatc
    10501 gcttaccaac atttgctttt atatttgcta aactttcaga aaaaagttgg agtatatgat
    10561 gctaggtgat tgcgtcatgt tagtaaacga aatggaaata actgatcata gagtagataa
    10621 cttatttgaa aaagggaaaa atgagataaa agatccatgt agtagattta gcaataggac
    10681 atataaaagc tttagaaaaa gtatctgaaa aaacagatgt ttatatctat aacctatgct
    10741 cgggagaagg cactagtgta ttacaacttg taaatacatt tgaaagtgtt aataagatct
    10801 ctattcctta taaaatagtt ccaagacgtt caggagacgt tgcaacttgt tatgcaaatg
    10861 cagacaaagc atataaggaa ttaaattgga ggacaacaaa atcgattgaa gacatgtgta
    10921 gagatacatg gaattggcaa tcaaaaaatc ccaatgacta taattgatga tactgtctat
    10981 atgagtgctg tattttggaa aaattactta accttttaat gaaatgcata tttaatgaaa
    11041 gataaattaa aaaaaatgtt tgacagcgct tgacaaagga aacggtttca ttgtataatg
    11101 taaacatagt gacaccgata tcaaatataa aaaagaaggt ctttatatga aaaacttaac
    11161 aaaaattaag ttcaaagaga atggggaatt taatcatttc cctgggaata cagttgtagc
    11221 aaatctttat actaaacaag atttgatgga agttgttgat attattcaat cacgttatag
    11281 agaattacca tttatcgata agtttacttt aactccaagg aattctattc acatgactgt
    11341 aattgaattg ttgtgccatg aaaatcgtga aacggagttt tggagcagta atcttcctct
    11401 agatacacct ttacaggaaa tacatgatta ctttgctaaa caacttgaaa tttttccatt
    11461 gttggatgaa gaaattcata tgcgtgtaac tgaaatggga aaacaaaaca tactagttga
    11521 acctgcagat gaagcttctg caaagagatt agaagaaatt cgtacttatg tctcagaaaa
    11581 agcaggtgtt cgtttcccta atcatgatag atatcaattc catatttcaa ttgggtatct
    11641 tcggattcct ctaaccgaag aggaggaaga agagtttact aaagtcagag cagaattaac
    11701 tgaaatttta ttagagaaga ttccaactat tactgtaaac cgtattgact atactgtatt
    11761 tgaagatatg agacaatttg tttcatatca cgaaaaattt aaataaaata ataaaaaagg
    11821 agaacttatc atgaaaaaaa tgaaagtttg gtctactgta cttgcaacgg gagttgctct
    11881 tactacactt gctgcttgct ctggaggttc aaattctacg actgcttctt catctgaaga
    11941 aaaagctgat aaaagtcaag aattagttat ctattcgaac tcagtctcaa atggtcgtgg
    12001 tgattggtta actgctaaag caaaagaagc tggttttaat ataaaaatgg ttgatatcgc
    12061 tggcgctcaa ttagcagacc gtgttattgc tgagaagaat aatgcagttg cagatatggt
    12121 atttggaatt ggtgctgttg actcaaataa aattagagat caaaaattac tagtacagta
    12181 caagcctaaa tggttagata aaattgatca atctttatca gataaagata attattataa
    12241 cccagttatt gttcaaccct tggtattgat tggagctcct gatgcaaaag aaatgccaaa
    12301 agactggaca gagttagcta gtaaatataa gggacaatat tccatttatg gcttaactgg
    12361 tgggactgga cgcgccattt acgcaagtat tctagttcgt tatcttgatg aaaaaggtga
    12421 tttaggagta tcggaaaagg gctgggaagt tgcaaaagaa tactttgcaa atgcctatac
    12481 tcttcaaaaa ggtgaaagct cagttgttaa agcgttagat aaagaaagcc caattcaata
    12541 cggtatgatc tgggggtccg gggctctagt tggtcaaaaa gaacaaaatg ttgtttttaa
    12601 agtgatgtct cctgaaattg gggttccatt tgtaactgag caaacaatga ttttgagtac
    12661 aagtaagaag caagcattgg ctaaagaatt tattgattgg tttggtcaat ctgaaattca
    12721 agtagagtac agtaaaaact ttggctctat ccctgccaat aaagatgccc tcaaagagct
    12781 accagaagat actaagaaat ttgttgatca agtgaaacca caaaatattg actgggaagc
    12841 tgttggaaag catttggatg aatgggtaga aaaagctgaa ttagaatacg tacaataaga
    12901 aataagagtt attttttatg tccaagtctc tctattattt ctaaatttaa ggaagaaata
    12961 aagagaggct tttggtttag taatagaggg agttagtgag atgattaaat ttgataatat
    13021 tcaaattaaa tatggtgatt ttgttgcaat tgataatctg aatttagata tacatgaagg
    13081 ggaattcttt acatttcttg ggccttcagg atgtggtaaa tcaactactt tgagagcatt
    13141 ggtaggtttt ttagatccat catcaggaag tattgaagtt aatggaacag atgtcactca
    13201 tttggaacct gaaaagcgtg gaattggtat tgtatttcaa tcttatgcgc tatttccaac
    13261 tatgactgtt tttgataata ttgcatttgg tttaaaagtt aagaaggtag ctccagatgt
    13321 tattaaagct aaagtatcag cagtggcagc aaaaattaag atctctgatc aacagttaca
    13381 gcgtaatgta tcagaattat ctgggggtca acaacaaagg gtagcattgg ctcgtgctct
    13441 ggttcttgaa cctaaaattc tttgtctaga tgaaccattg tcaaaccttg acgcaaaatt
    13501 acgtgtagat ttgagaaaag agttgaaaag acttcaaaaa gagttaggta ttactacttt
    13561 atatgttact catgatcaag aggaagcctt gactttatct gatagaattg cagtctttaa
    13621 caatggatac atcgaacagg tcggtacacc agtagagatt tatcataatt ctcaaactga
    13681 atttgtatgt gattttattg gagatattaa tgttttgacc gatgaaacag tccacgaagt
    13741 attattgaaa aatacaagcg ttttcttaga ggataaaaaa ggatacattc gattagagaa
    13801 agttcgattc aatcgtgaaa ctgaacaaga ttttattcta aaagggacaa ttattgatgt
    13861 tgagttttct ggagttacaa ttcactatac aataaaagtt tctaaaagtc agattcttaa
    13921 tgtaacaagt attgatagtc aggctgctat tagatctgtc ggagaaagtg tggaattatt
    13981 tatcacacca tcagacgttc tgcaatttta aggaggtgca gtatgcgtca taaattaaat
    14041 ttaaaagatt ggcttattcg tttagggtta atctggttct tagtaacatt tattatttat
    14101 ccaaactttg atctagtagt gaatgtattt gtaaaaggag gagaattttc ccttgatgct
    14161 gtacatcgtg ttctaaaatc tcagagggca cttcagagta ttatgaacag ttttaagtta
    14221 gcattttcac tcattattac agttaatgtc gtaggtattc tttgtgttct atttacagag
    14281 tactttgata ttaaaggtgc taaaatttta aaattaggtt atatgacctc tttaatttat
    14341 ggaggagtgg ttttagcgac tggatataaa tttgtctatg gtccttatgg attgattaca
    14401 aaatttttac aaaatgttat cccttcttta gactctaact ggtttattgg gtatggtgca
    14461 gtcttattca ttatgacatt ttcaggaact gctaatcata cattgttttt aacaaataca
    14521 attcgaagcg ttgactatca cactattgag gctgctcgaa atatgggagc aaaaccattt
    14581 actgttttcc gaaaagtagt gttaccaacc ttaattccaa ctctatttgc acttactatt
    14641 atggtttttc ttagtggttt atctgcagta gcagcaccca tgattgttgg tggtaaagaa
    14701 tttcaaacta taaatccaat gattattaca tttgcaggga tggggaattc tcgtgattta
    14761 gctgccttac ttgcaattat tttaggtatt gcaactacaa ttttgcttac tatcatgaat
    14821 aagatagaaa aaggtggaaa ttatatttct atctctaaga ctaaagcgcc tcttaaaaaa
    14881 caaaaaattg cgtctaagcc ttggaatatc attgctcaca ttgtagcata tggattgttc
    14941 acagttttca tgcttccact aatttttata gtattatact catttacaga tccagttgca
    15001 attcaaacag gtaacttaac attatcaaac tttactttag aaaattatcg cttattcttt
    15061 agtaatagtg cggcattctc tccattcttg gtcagcttta tttattctat tattgctgcg
    15121 acaacagcaa caattctcgc agttgtattt gctcgtgttg tcagaaaaca taaatctcgt
    15181 tttgatttct tatttgaata tggtgctcta cttccttggt tactaccaag tacactttta
    15241 gcagtaagtt tattatttac ttttaatcag ccacaatttc ttgtcttgaa tcagattttg
    15301 gtaggtagtt tggtaattct acttattgca tatatagttg taaaaatccc attttcttat
    15361 agaatggtac gtgctatttt atttagtgtt gatgatgaga tggaagatgc agcaagaagt
    15421 atgggtgctt caccttttta tactatgatg aaggttatca ttccatttat tttaccggtt
    15481 gttctctctg ttattgcttt aaactttaac tctttattaa ctgacttcga cttatctgta
    15541 ttcctttacc atcccctagc tcaaccatta ggtattacga ttcgatctgc aggtgatgaa
    15601 acagcaacat ctaatgcaca agctctggta tttgtttata caattgttct gatgattatt
    15661 tctggaacgg tattatactt cacacaaaga ccggggcgta aagtaaggaa ataatcatga
    15721 cagccactag tcttgggtta tcaaatattg aaatagttgt caggattgtt ttatcagtag
    15781 tcattggtag tataattggt ttagagagag ggagcaaatc ccagcctgca ggcatccgaa
    15841 cttatagtat tgtttgtcta gctgcatgtt tgattatgat gacgaatgaa tacgtatctt
    15901 ataaatttgg gacaggagat cctacacgat taggagctca agttatatca ggtgtgggtt
    15961 ttctaggcgc tggaacgatt cttattacag ataaaaagaa aattacaggt ctgacaactg
    16021 cagcaggcat ttgggcttcg gcaggaattg gattagctat tggagtaggt ttttatgagg
    16081 gagctctttt agtagccatt tctgtttggg gtgtgatatc catgttccaa ccactaaaaa
    16141 aatatctgca aaatcgttct aaaatgattg aattgtatat agtggttaaa tctacagaag
    16201 cctataatcg tgtattggtt tattgtgcag aaaatggtat cagaatgacc gattcaagaa
    16261 cagcgtttgg agatgttaat tctgacagaa ttgaatactt tgatgttccg gacaaaaaaa
    16321 tagcgtcatt tattactctg gaattatcag gtagatttga acatcttcga ctgatggaag
    16381 aaattgctaa tattgtaggt gttatttatg tcgaagaaat tagctgaaat ttagtaaaca
    16441 aagggacaga tgtttttgtc cttttgcttt ttagatgttt taatcatcta atttttgagt
    16501 agatttttgc tcagaggttt ttatgaaaga ttataaaatc aattttgatt taggtaaaat
    16561 agaatatttt gataataatt gtttgataca agtatacaaa tttatttctt tttatgatat
    16621 ttgtgaaatg gtgtttgcct ttcatttacc tcctgatgag ttgataacaa atgttatctt
    16681 taaagaaaaa attaactcta tgttaaaatg ttacattgac aggctattat atgtttttat
    16741 aaatcctaca cattttactg aaaaagttaa tctacaattt tatggcagtt ttttctcata
    16801 tgaatttatt tgtcgtgaag ttggaaacat tcttaaaaat aaaggtgtga aatgcaattt
    16861 aaactttttt gaaggggaag aatatttgta aaattaattt tgtgaatttg tggatcttaa
    16921 ataatttact aaattctctt gttaaaaaaa attaaatatt gtatagtaat attagaatgt
    16981 ttgtaataga ggactgaaat gaaaaatata aatgggaaaa aggtaactat ttatgatatt
    17041 gcacgtttat caggtttttc tccaaaaaca gtttcacgag ttattaatgg tggagtaaat
    17101 gttaaagaag aaacttatca agcgattcaa aaagttatag aggaattgtc gtatattcca
    17161 aatgcgtatg caaaaaattt aactaaaaaa gaagctataa atatattgat ttctgtaaaa
    17221 aaaatcgact cttttccttt aatttggttt catacgctgt tagataaagt gttacggacg
    17281 tgtaaagaat ttggtgttaa tgctatagtt gagtactttg gagaggagga tacaattagt
    17341 aattcgatta tatcaagcac aggtagccta gtagatggtg ttattgtttt ttatgaaagt
    17401 gtagatgata tcagaattca gtatttaaag aagaaccata tgccttttct tgttttcggt
    17461 gaatctcaaa cgtctggagt agtctatgta tctaataata attttcaagc tacttatgat
    17521 atgatgaaag ctgtaactga agaaaaattt aaaaatatgt ggttgcttat gggaggagaa
    17581 tcccatgtta ataaggatcg tgaaagaggt gtgcgttctt ttctgaatga taaaaattac
    17641 tttatggatt taaaagtcat ttatggctta tctacaattg attcagttta ttcttatgca
    17701 atgcagcact tgactaccca aaattatccg gacattattt ttgtttcagg agatgaaaag
    17761 gttcagggct tgattcgtgc gtgctatgag aaaggaattc ttattccaga tgatatttct
    17821 attattggat ttgataatat tcctatttct cagtattata ctccagcttt gtctacaatt
    17881 gctcccaatt atgttaaatt ggctaaagaa atgatagaag gtgttttagc aattattaaa
    17941 ggggaaagtg tcacatctgt tgaagtttct cctaaatttg ttaggagaca gagtttctag
    18001 tattgtttaa ttcttgaaaa tcctagtgga aaagatggag tgttctaaaa taagttctgt
    18061 ttagcctcca ttcagtttct attgagttgg atccaatttc taacaagtgg gacatgttca
    18121 tgttcgatct aaggaagaca tggtcacatt cgaatgatat tttcaaaaaa atcgtaaaaa
    18181 agtcttgaca aagaaaaaac aaagtattaa aataagttca acaaatcaga aaagtaacta
    18241 tttttgatct tcagggagcc tgtggtggtt gtgaataggt ggttggaagt agtgaaagtg
    18301 ggctgatttt gaaaatgaat ttgaaacaat gaaaattcgg tgcgcacacc ttacagtgca
    18361 gcttgttgtt aaacaaggca gagatgtaaa gggatagtcc ctttataatt gaggtggcac
    18421 cgcgttacca acgccctcac acggaagtat attttgtgtg tgggcttttt tctatccgtc
    18481 gtttggttta tcttttatta gggccttaag tcgctttgat gaacttgagt tctatctaca
    18541 gctccttgcc tactactaaa agcaaacaaa aagctggact aatacgaaaa aagctagtaa
    18601 tactcaatga aaatcaaaga gtaaactagg aaactagccg caggttgctc aaaacactgt
    18661 tttgaggttg tggatagaac tgacgaagtc agctcaaaac actgttttga ggttgcagat
    18721 agaactgacg aagtcagtaa ccatacctac gataaggcga cgttgactcg gtttgaagag
    18781 tttttcgaag agtataaagg tgtaccgaga tgaatatctc ttcatcaatg tctctggtcg
    18841 tggaggcaag gacctagctg cgattgcaga ttactagaag ctaaaaaata atagatggaa
    18901 aaattacagt tctttctctc acagagagct tgtggttgct gaaaacaagc agagaaagct
    18961 gtaaagttgg gttcatctga aacgagagaa gaaaacatca ttctcaaggg agtgcccttt
    19021 atcgcacagc ctgttacagg aggtatctga gataggaatg agagatagga gaaatcctat
    19081 aattgaggtg gcaccgcgaa tttcgtcctc acgcaagtta ttttgcgtgg ggatttttca
    19141 tacagtcgcc acgaactaga attagaactg aaagggaaat tacaatggaa cgaatcattc
    19201 atggagatgt cttatcacca atcttggctt atatgcgctt aaaggggcaa cataaggtta
    19261 ttttagagag tattccgaga gacaaggaaa cagctcgttt ttctatccta gcctataatc
    19321 cagtttttga gattaagttt gaaaatggag ttctctatca aaatggtcaa gtgattgatc
    19381 gggatccctt ggatctcctt tatgaagtga ttcataagag tcagcaccac tcagagctac
    19441 cttttggtgg tggagccatt ggttttgtgg gttacgatat gatttcgctt tatgaagaaa
    19501 ttggtcaaat ccctgaggat acaattggga cgccagacat gcatttcttt gtctatgaga
    19561 gctatatggt ctttgaccac aagaaggaga agatacatgt catagaggat gctctctata
    19621 gtgagcgcag tcaagaggtc ttggaaaaat ccttgaacca agtgcttgag gaattacgca
    19681 ttcctgctcc aaatgaattt gaagacttgg atttatcacc acttgacttc aaaccgcata
    19741 tcgctccaca taagtttgag ggaatggtag aaacagctcg tgacttgatt cgtaatggtg
    19801 atatgttcca atgtgtactc agccagcgtt tctcagcaga agttactgga aatccatttg
    19861 acttctacag aaatctccgc gtgatcaatc catccaatta cctctatttc tatgattttg
    19921 gggattatca aatcatcgga gccagtccag aaagtttggt ttctgtcaaa aatggcatcg
    19981 tgacaaccaa tccgattgca gggacgcgac caagaggggc tacggatgaa gaagacaagg
    20041 ccttggcgac tgacctcctc tctgatgaga aggaaacagc agagcatcga atgttagtag
    20101 acctgggtcg taacgatatt ggccgcatct ctgaaacggc cagtgtccaa gtcactaagt
    20161 atatggaagt ggagctcttc cgttatgtta tgcatctgac cagcgtggtc aaggggcgtt
    20221 tgcttccaga actcattgct atggatgcct tgaaatcaac gcttccagct ggaaccgttt
    20281 ctggagcacc aaaaattcga gctatgagac gcatctatga actggaaacg gaaaaacggg
    20341 gcgtatatgc aggagcaatc ggctacttgt ctgcgacggg tgatatggat ttggccattg
    20401 ccattcgaac catgattctc aaaaatcaaa gagcctatgt gcaggctggg gcagggattg
    20461 tctacgactc tatcgcccaa aacgaatacc aagaaaccat taacaaagca aaatctatga
    20521 ctagaattgg agaactaaga ccatgatttt attgattgac aactatgatt cttttaccta
    20581 taacttggcc caatacatcg ggaattttgc agaagttcag gttttgagaa atgatgattc
    20641 caagctgtat gaagaagctg aaaaagcaga tggtctggtc ttttctcctg gtcctggttg
    20701 gccagttgat gctggaaaga tggaagacat gattcgtgat tttgcaggca agaagccgat
    20761 tctagggatt tgtttgggcc accaagccat tgcagaagtc tttggtggta agctaggttt
    20821 ggctccaaaa gtcatgcatg ggaaacagag caatatcaac tttgaagcgc catctgtttt
    20881 gtatcaaggt attgaggatg gacgtgcggt catgcgttat cacagtattt tgattgagga
    20941 aatgccagaa gactttgaag tgacagctcg ttcgactgat gaccaagcca tcatggggat
    21001 tcaacataaa aacctaccga tttatggctt ccagtaccat ccagagagca ttggaacgcc
    21061 agacggcttg tcttctattc ggaattttat cgaggaggtt gtaaagtgag gaaactagga
    21121 tgaaagagat tattgaaaaa ctagcaaaat ttgaaaattt atcaggtgtg gaaatgacgg
    21181 atgtcattga gcgtatcgta actgggcgtg taactgaagc gcagattgct tctctcctct
    21241 tagctcttaa gatgaagggg gaaacacctg aagaacgcac agccattgcc caagtcatga
    21301 gaggacatgc ccagcatatt ccaactgaga ttcatgatgc catggacaac tgtggtacag
    21361 gtggggacaa gtctttcagt tttaatattt ccacaactgc agcctttgtc ttggctggtg
    21421 gcggtattca catggccaag catggtaacc gctcgatttc ttctaaatct ggttccgcag
    21481 atgtcctcga agccttggga atcaatcttg acctcaaacc agctgaacta ggtaaggtct
    21541 ttgataaaac tggaatcgtc tttctcttcg ctaaaaatat gcacccagct atgaaataca
    21601 tcatgccagc tcgtttggaa ttgggaattc caacgattat gaacttgact ggtccactga
    21661 ttcatccaat ggctttagaa acacagcttc ttggaattag tcgtccagag ctcctagaaa
    21721 gtacagctca ggttttgaaa aatatgggtc gcaaacgtgc catcgtggtt gctggaccag
    21781 aagggttgga tgaagctggc ttgaacggaa caaccaagat tgcacttctt gaaaatggcg
    21841 aaatcagctt gtcaagcttt actccagagg atttgggaat ggaaggctat gctatggaag
    21901 atattcgtgg tgggaatgct caggaaaatg cagaaatttt gcttagcgtt ctgaaaaacg
    21961 aagcaagtcc attcttggaa acgacagtct tgaatgctgg tcttggtttc tatgctaatg
    22021 gtaagatcga tagcatcaag gaaggagttg ccttggcccg tcaagtgatt gctagaggca
    22081 aggcccttga aaaactcaga ctgttacagg agtaccaaaa atgagtcagg aatttttagc
    22141 acgaatctta gagcagaagg cgcgtgaggt ggagcagatg aagctggagc aaatccagcc
    22201 tctgcgccag acctatcgct tggcagaatt tttgaagaat catcaggacc gcttgcaggt
    22261 aatcgctgag gtcaagaaag ctagccctag tttgggagat atcaatctcg atgtggatat
    22321 tgtgcaacag gcccagactt atgaagaaaa cggagcagtg atgatttcgg tgttgacaga
    22381 tgaggttttc tttaaagggc atttggatta tctacgggaa atttccagtc aggtagagat
    22441 tccgacgctc aacaaagact ttatcataga tgaaaagcaa atcatccgcg ctcgcaatgc
    22501 aggtgcgaca gtcatcttgc tcattgtggc agccttggca gaagaacgtc ttaaggaact
    22561 ttacgactac gcgacagtgc ttggtctgga agtcttggtg gaaactcaca atctagctga
    22621 actagaagtg gctcacagac ttggtgccca gattatcggg gtcaataacc gcaacttgac
    22681 cacctttgag gtcgacttgc agaccagtgt agacttggct aaacatttca aagatgattg
    22741 cttgtacatt tctgaatctg ctattttcac agggcaggat gcggaacgac tagccccata
    22801 ctttaacgga attttggtag ggacagctct tatgcaggca gaaaatgtgg cccagagaat
    22861 caaggagttg cagattgaca aaggttaaga tttgtggact atcgaccaaa gaagcggtgg
    22921 aaacagccgt ttcagcagga gccgactata tcggttttgt ctttgcacct agtaaaagac
    22981 aggtgacttt agaagaggca gctgagctgg caaagcttat tccttcaggt gtgaaaaagg
    23041 ttggagtatt tgtttcacca agtcgggtag aactgctaga agtcattgac aaagttggct
    23101 tggacttggt tcaagttcac ggtcaggtgg cagatgattt atttgagaat ttgccttgtg
    23161 ccagtattca ggctgtgcag gtagatggaa atgggcatgt ccccaattct caggcagatt
    23221 atctactctt tgatgcccct gtggcaggaa gtggtcagtc ctttgattgg ggtcaactgg
    23281 atacgactgg actagcacag cccttcttta tcgcaggtgg ccttaatgaa gataatgtag
    23341 taaaagcaat tcaacatttt actccctatg cagtagatgt atcgagcgga gtggagacag
    23401 atggacaaaa agatcatgaa aagattagaa gatttataga gagggtaaag catggcatat
    23461 caggaaccaa ataaagatgg attttacgga aaattcggcg gacgttttgt cccagaaaca
    23521 ttgatgacag cagttttgga gttggagaag gcctaccgtg aaagtcaggc agacccaagt
    23581 ttccaagagg aattaaacca acttttgcgc cagtatgtgg gacgtgaaac tcccctttac
    23641 tacgcaaaaa acttgaccca gcatatcggc ggagccaaga tttatctcaa acgggaagac
    23701 cttaaccata caggagccca caagattaac aatgccttag gacaagtttg gcttgccaaa
    23761 cgcatgggta aaaagaaaat tatcgcagaa actggtgctg gtcagcacgg tgtggcaact
    23821 gcaactgctg cggccctctt taacatggaa tgtaccatct acatgggtga ggaagatgtc
    23881 aaacgccaag ccctcaatgt cttccgtatg gagcttttgg gagctaaggt cgaggccgtg
    23941 acagatggtt cgcgcgtgct caaggatgcg gtcaatgcag ctcttcgttc atgggtggct
    24001 aatatagatg atacccacta tatccttggt tctgccttgg ggcctcatcc atttccagaa
    24061 attgttcgtg acttccaaag tgtcattggt cgagaggcta aacaacagta ccgtgacttg
    24121 acaggacaaa atctgccaga tgccctagta gcctgtgttg gtggtgggtc gaatgccatc
    24181 ggtctcttcc atccctttgt agaagatgag tcagtagcca tgtatggagc tgaagcggct
    24241 ggacttggtg tggatacgga gcaccacgca gctaccttga ccaagggtcg tccaggtgtc
    24301 cttcacggtt ccctcatgga tgtgctccaa gatgcccatg gtcaaattct tgaagccttc
    24361 tctatctcag caggtttgga ctatcctggt atcggtccag agcattctca ctaccacgat
    24421 attaaacgtg ccagctatgt ccctgtgaca gacgaagaag ccttggaagg attccaactc
    24481 ttgtctcgtg tggaagggat tatcccagcc ttggaatcta gccatgctat cgcctttgcg
    24541 gtgaaattgg ccaaagaact tggaccagaa aagtctatga ttgtctgcct atcaggtcgt
    24601 ggggacaagg atgtggttca agtcaaagac cgcttggaag cagatgcagc aaagaaggga
    24661 gaagctcatg cctaagacac taacagaaaa attgaatgct ataaaagcaa ctggaaaagg
    24721 aatttttgtt ccctatatca tggctggtga ccacgagaaa ggtttggacg gtcttgctga
    24781 aacaattcac tttttagaag atttgggtgt ctctgctatt gaagtgggta ttcccttttc
    24841 agaccctgtt gcagatggac ctgttatcga agaagctggc ttgcgcagtt tagcccacgg
    24901 gacctctacc caggctttag ttgaaacctt gaaaaccatt gaaacagaga ttccactggt
    24961 catcatgacc tacttcaacc ccctctttca gtacggtgtg gagaactttg tcaaagatct
    25021 ggctgataca gctgtgaagg gcttgattat cccagacttg cctcatgaac atgccaactt
    25081 tgtaaaacca tttttggcag atacagatat cgccttgatt cctttagtaa gcttgaccac
    25141 aggaattgag cgccagaaag agttgattga aggcgcggag ggattcgtct atgccgttgc
    25201 catcaatggg gtgacaggga aatcaggcaa ttaccgtgca gatttggaca agcacttggc
    25261 gcaacttcat caagtggccg acatcccagt cttgacaggt tttggtgtat ctagtcaagc
    25321 cgatctggaa cgcttcaatg cggtgtcaga tggtgttatc gtcggttcga aaatagtaaa
    25381 agctctccac caaggagagc cgattcagga ttttatcaga caagcagtag cttaccaaaa
    25441 ataatcaaac aagtagcaag taagaggaaa ggcacgaaag gaagtctttc ctttttcttt
    25501 tgcaggagaa aggctagttt tatagtgaat tgaatctgga atattacact acggttccta
    25561 aaatatttta agaaagtgat ttgaatttcc caataaattt gttcagtttt taattgattt
    25621 tactatagaa gatataattt tctaaattac tctgacacag aactttaaga aaaagctaat
    25681 tattgtagta atttctttaa gaaaatgata taattcatta aaaagtattt ggaggaggaa
    25741 gaattatgtt gaatcaggat ctctttgatt cgcttgaggc acaaaaaatt gtagatactt
    25801 tgatgaaagg gcaaaaagat tatgtagatg aacgtctaga aaaaagatta tgtagatgaa
    25861 cgtctagaaa aaagagagac aatgatagtg tcgaatggtt atgcatggac gcgacctaat
    25921 catattgata ctgcatttgc atcagcagat ttgtttgagt ataaattaca attagcagga
    25981 cagacttggg gatatttaga atttgaaaca aatacagaaa aatatgggaa agtattgtta
    26041 attataaagg gtaagaagcg acttacgaac caatttcctt tggtacaaaa aaataagagt
    26101 ggctacttat ttgaatatgc tcaaatgaat acactttatc ttaatcaaca ttcttcctac
    26161 aaaaatgatg aagatagtca ttcctttcca attcagatgg agttagtttc tgatgaaatg
    26221 attcaagaaa ttgaacaagc taccaaaaat tcgaatatcg aaaaatttat gattttaact
    26281 tatgaggcgg actcagaaaa caatattata tatgtagatg ttgttatgcc tgatgcacga
    26341 actggtcagt tacacttgat tcaagatttg tctgagtata ttcaatcaag ttcgtaccat
    26401 ttcgaagaag ctaaatatca agatattcct aatttttcag aattatcgga aacagaagat
    26461 tttgaaatta ttccaagaat agaaaaacaa gaaggtcaaa agtagtaagg agtgtgtaaa
    26521 tgtttaatgg tcgggtattg aaagaattac ggctgttaaa tggtttaagt agagcagaat
    26581 tggctcagag aattaattta acggaacaag ccatttggca gtttgagtcc aacgaaacga
    26641 aacctaaatt atcaaccaaa atgcatttgg ccaaccaatt tcatgttgat ttaacttatt
    26701 ttgaacagga agaagagagc attcgatttg attcttctgt aattgccttt agaaatgcag
    26761 acctagcaac acggaaaaca atagatattc aaactatgta tttacataag gtagatagtt
    26821 tgattgatta ttttgaaagt tttgtaatta tacctaatat tacaattcat gatctaagta
    26881 atgtagtgag tgaatcttat cataagggag aatccattga ggaattggct ctttatgcca
    26941 gagaaaaatt aggtatttca aaagataatc atgatttgct ttataaatta gaacgttcag
    27001 gcatctatat cgtggaacga ttaattaatg gccaagctga tgcttatagc gcatggtcaa
    27061 aattgggaag accttatatt gtgttgggaa cgaataaatc atctgtacgt cgaaattttg
    27121 acttagctca tgagctagga catattcttt tacataaata taaagatatg aatgaagatg
    27181 gcgatcgttt ggagcaagaa gcaaattatt ttgcatcatg ttttttattg ccaaaagaag
    27241 agtttttagt caaatttgaa gagagggttg gcaagcgtgt cagcaatcct gatagttata
    27301 ttttattgaa gtcggatttg aatgtttcga tacaggcttt agagtatcga gcttttaagt
    27361 taggattatt gactccaaag caacattctt acttttatcg tcaaattgcg caaaaaggtt
    27421 acaaaatgat tgaacctttg gatgatcaaa tttttgttaa aaaaccaagc aaagtaaaga
    27481 gtattctgga cgtcgttttg agtaatcatc tagtcagtct agcgactata atgtctaaac
    27541 aaagtattcg tttacagttt ataagcgaaa tattttcagt cgaaatgaaa ttttttgatc
    27601 agtatcaaga agatagaaga acagatcgat ttgataacat catccctttg tacaaaagaa
    27661 ataatttata atttaactgt gaaataattt catgaaggac atatggcaga aattggactt
    27721 tatcaaacaa gcagtagctt accaaaaata atcaaacaag tagcaagtaa gaggaaaggc
    27781 acgaaaggaa gtctttcctt tttcttttgc aggataaagg aaaggatacc catcgcagaa
    27841 gcaaactgaa tcaagattag taactccgtt acgctaaaga cgagagcaca agaagctaaa
    27901 aagaggaaat cccctgcgcc catgcggata tcgataaaat gagccaaaat tccaagagca
    27961 aggaaggaga ccatgaccag attccagcca gagtaagcta tgaggattag gtggaaagtc
    28021 atccagacca gtaagggata ttcctgatgg cgaaagtcgt agatacccaa ggtcaaacca
    28081 gcagtgatta ggatgacttg tcccaaggag agccatcccc aagagtaaag cagaaagatg
    28141 agtcctaagc ctagttcaaa gagggcatac cagacgggat agcggacctt gcagtagcga
    28201 cagcgaaaat gattaaaaac ctgcgataga atcggaatca aatctaaggg acgcaagcga
    28261 gtctgacagg aatcgcagtg actggctgaa ctgataatgg attgctctgg aaaacggtca
    28321 atgaccaaac caagaaagga ggcgagaatg ctcccgacga gaaaaaaata aaaatcaatc
    28381 atacttatct attcgtaaaa aatgggagaa atagtataat ggagaaacat agataagatg
    28441 gtgaggaaaa gatgacaatt cgttttgaag aaaaggtgag cacagaaaac gctcaattcg
    28501 tatgccagtg gtccaactcc ctaggcaaat cctttcaaga acaatggatg ggaccaagga
    28561 ttccttttct actgaccctt caagccttgc aagacttgga aggagtcttt tcaatctttg
    28621 atgaacaaga gtttgtggaa cttatccata aaatcaggct agaagacagc aatcttcata
    28681 tcgggagatt ttttatcaac ccccagaaac aggggcaagg cttaggtagt caggctttaa
    28741 ggaaatttgt tagtttggcc tttgaaaatg aagatataga tagtatttct ctaaatgtct
    28801 tagaggcaaa tcaaagagct cagaatcttt accaaaaaga aggatttgaa atcgttcaaa
    28861 tggttgaagc acctgtacga aaatatatca tgaaaaaggg gagatagaaa gcaaacagcc
    28921 ttgaaatcaa tgttgactgc gattatgaac ctgaatcagc ccctcaaaag ggactgtata
    28981 tgaatgaacg ttaccagtgt ttaaaaacta aagaatatca ggcactttta tcttccaagg
    29041 gtagacaaat tttcgctaaa cgtaagattg atatgaaatc tgtctttggg cagataaagg
    29101 tttgtttggg ttataagaga tgtcatctga gagggaagcg tcaagtgaga attgacatgg
    29161 gattcgtact catggccaac aacctgctga aatataataa gagaaagagg caaaattaaa
    29221 aagctagagt tccgcaattg ggaatctcta gctttttgtt ttctgagaat catcttgact
    29281 cagactcttt tgactaatgt tactaaaaag ataaagtaac ttttaacctt atttatcgtc
    29341 gccactcaac atgtttttaa caccttctac agcaccttct acagcgtctt tggcatcttc
    29401 ggcgacttct tttactttag aaacaacttt ttcagctact ccttcttttt ccattttttc
    29461 atcaccgatg gctttcccaa caccttcttt aatagaacct ttagcttgat ttaatttttc
    29521 ttctactgac atgataattt ctcctgttat atttatttta tcttagttta cacgagtgtt
    29581 ttcgtgagat actacaccat ttgctgcacc tttaacagct tctacacctt cgctaacttt
    29641 ttcttgaaca gttgagaaac cagatccaag accagattta gctttttcga attgttctga
    29701 agtgaattct cctgttgatt cagcaacgtc agatacgcga tcttgaaggc ttactgaatc
    29761 tgcttcatgc tgttctttag ttttgatgtc gacaacgttt acgttgattt caacaacttc
    29821 caagtcagtc attttagcaa cttctgaaga tacgatttct ctgatttctg aatataaagc
    29881 tggaacattt ttttggtact caacaataac gtttaagtca actgcaactt gtgttttacc
    29941 aacttctacg ttaacaccac ttgttacgtc atcgctgtta acgatttttt ctttaagatt
    30001 tgagaagaaa ccaccatcga ttcccaaaag acctgaaacg ttttctagtg aaagaccaat
    30061 gattttttgg ataactttat cttcgtaagt aagttcccct ttgatttcgt gagctacaac
    30121 agtagcatct ttcttttcta cgttagtgtt tgtgtttttt tcgtttgaca tatgaaactc
    30181 ctttaattaa attagtaatt tttatttatc tatatagttt ttttcgatat ataatccagc
    30241 tgcaactccc agtgctccta aaatcaatac aaatattgtt ttgaagaagc caaaggagac
    30301 aatcaaacaa gcaagaaata cgcctatgag accagcgata attggatatc gatattgttt
    30361 aagccattcc attttttact tccttacttc acacgactaa cagtcttttt gttttgaggt
    30421 tttggttggt aattttttac tgcaacttca agttttactt gacgctcaat accaaaaaac
    30481 tgcttcaatc cattagttat ttcattttga attatttggc atctgtcaac gatgttgtct
    30541 gaaggaagaa ttttaccttc tacatgaacg aaacatttat tttttcgtaa atttacatga
    30601 acagttgggt tcttgatcaa tctatgatca agaaccaaac ttctaacaaa accttcgatt
    30661 gccgaattct ttaattttaa tgtatcgttt ttagtttcaa gttggatttc caagtaacgt
    30721 ttaggataaa acatcacaac taaaatggat aataaaacta aagttgatag aaccactgtc
    30781 ccccaaaaga catatctagc aagatagaat tcaactgcgg agttctgtct ccagctaagt
    30841 agttgaatac ctagatcact aacttgatga taatctatca aaacaggaag gaaaattgtc
    30901 aagattaaaa tacagaaaat aatgaaacat attttctttg cttttgacat atacaatcct
    30961 ttcgatttaa catttaaact atttttcccg tcattgattt aaaaatagtt tgctaacttt
    31021 actggcgaaa agttcacttt ctacctgtaa agaatgacac tacagtaatc ataatcgctg
    31081 cacctacaat aaatgggagc aaagccattc cagcgattga tggcccccaa ctacctaaaa
    31141 gagattgtcc tgcagatgcc ccgattaaac cagcgaatac atttgcgatg tttcccatag
    31201 aactaccttt tttagtgatt ttacctgcca agagaccaat aagacctcca gcaataatta
    31261 atcacaacat tgcctaccct ccttttttat tttaatatca aaaaatcaat ttctttgatt
    31321 actactatta tataacttta atatagaaaa gtcaattatt ttgattatta ttattatata
    31381 attttaatat taaaaatcaa attctttgat tgttgctatt atataatttt taaaattaaa
    31441 aatataatct ttagacttga atttgattct gtattcacgc cctcaataga cggtaaaata
    31501 agaaaattgt ttatatattg tctccgtagt gttattatac gaaataaaag attttaggaa
    31561 aagtcgttat atcatgctat acctattctt tgtggtataa ttgcaagagg tttaatccga
    31621 taatttataa agagagaaag atattcatga gagatttatt atctaaaaaa agtcataggc
    31681 aattagaatt attatttgaa cataaacgtt ggtttcatcg ttctgaacta gcagagttat
    31741 taaattgtac agaacgtgca gtcaaagatg atctatccca tgttaaatct gcttttcctg
    31801 acttgatttt tcattcttct actaatggta tacgcattat taataccgat gatagtgata
    31861 ttgaaatggt ttaccatcat ttctttaaac attcaactca tttttcgatt ttagaattca
    31921 tcttctttag tgaaggttgt caagctgaaa gtatttgtaa agaattttat atcagttcat
    31981 cttcgctcta tcgtattatt agccaaatca ataaagtgat taaaaggcaa tttcaatttg
    32041 aagtcagtct gacccctgtt caagtcattg gaaatgagag agacattcgt tacttttttg
    32101 cacaatattt ttcagaaaaa tattatttcc tagaatggcc atttgaaaat ttttcatcag
    32161 agccactatc tcaattgtta gaattggttt ataaggaaac aagctttcca atgaatttgt
    32221 caacgcatag aatgctaaag ttgctcctag ttacgaacct atatagaata aagtttggtc
    32281 attttatgga agtagataaa gattctttta acgaccaaag tttgaatgct ttgatgcagg
    32341 cagaaggaat agaaggtgtt gctcagagtt ttgaatcaga atacaatatc tctttagatg
    32401 aagaagttgt ttgccaatta tttgtgtctt actttcaaaa aatgtttttc atagatggaa
    32461 gtctctttat gaaatgcgta aaaaaggata gttatgttga aaaatcttac catctattga
    32521 gtgattttat tgatcagatt tcagtcaagt atcagattga aatggagaat aaggataatc
    32581 tgatttggca tctgcataat accgcacatc tgtatcgtca agagttgtcc actgagttta
    32641 ttttatttga tcaaaaaggg aatacaatca ggaactttca aaatattttt ccaaaatttg
    32701 tttcagatgt aaaaaaagag ctttctcact atttagagac tcttgaggtt tgttctagtt
    32761 caatgatggt aaatcatcta tcttatacct tcatcactca taccaaacat ttggtgatta
    32821 atttgctaca aaatcagcct aaactaaagg ttttggttat gagtaatttt gatcagtatc
    32881 atgcaaaatt cgttgcagag acactttctt attactgtag caataatttt gaactagaag
    32941 tttggactga attagaatta tcaaaggaat ctttagaaga ttcaccttat gatatcatta
    33001 tttctaattt tattattcct cctattgaaa ataagagact catctattca aataatataa
    33061 acacggtctc actcatatat ttgttaaatg ccatgatgtt tattcgatta gatgagtaac
    33121 caaaaataac aaaaaaacgc tatttcgcgt ttgaactgta cctcaaaagt tagacagaaa
    33181 aaatctaatt tttggggtgt ttttgttaag aaaagacctt caatcattta agcaaaatgt
    33241 acatctagat ttatagcctt ctaaaactct tacttttttt gtagaagata cgaaaaaagc
    33301 catgaaacca ggctctataa tatttgtagt gggtaaatcc cctatggata ttatggagcc
    33361 tattttaggg tagaaaaaaa gtcccatatc atctataatg aaaagcgaca aaataactca
    33421 ttagaaagaa tcatatggaa caattacatt ttatcacaaa actactcgat atcaaagacc
    33481 ctaatatcca atttatggat atcattaata aggatacaca caaggaaatc atcgccaaac
    33541 tggactacga cgccccatct tgccctgagt gtggaaacca attgaagaaa tatgactttc
    33601 aaaaaccttc taaaattcct tatcttgaaa cgactggtat gcctactaga atcctactta
    33661 gaaagcgtcg attcaagtgc tatcattgct cgaaaatgat ggtcgctgag acttctatcg
    33721 tcaagaaaaa tcaccaaatt cctcgtatta tcaaccaaaa gattgcgcaa aagttgattg
    33781 aaaaaacttc tatgaccgat attgcccatc aactggccat ttcaacttca actgtcattc
    33841 gcaagctcaa tgacttccac tttgagtgta aggttagaaa tctgcctgag attatgtctt
    33901 gggacgagta tgccttcact aagggaaaga tgagtttcat tgctcaggac tttgaaaagc
    33961 tcaatatcat cactgttctt gaggggagaa cgcaagctgt cattcgagat cactttctta
    34021 aatatgatag agccgtccgc tgtcaggtga aaattattac catggatatg tttagccctt
    34081 attatgcctt ggctaaacag ctttttccat gtgctaaaat cgttctagat cgctttcaca
    34141 ttgtgcaaca tcttagccgt gctatgagtc gtgtgcgtgt ccaaatcatg aaccaattgg
    34201 atcgaaaatc tcatgaatac aaggctatca agcgctactg gaaactcatc cagcaagata
    34261 gtcgtaaact gagtgataaa cgattttatc gccctacttt tcgtatgcac ttgaccaata
    34321 aagagattct agacaagctt ttgagctatt cagaagactt gaaacaccac tatcagctct
//
LOCUS       DAVDZK010000023        32567 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVDZK010000023 DAVDZK010000000
VERSION     DAVDZK010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32567
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.024"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VUX16_001275"
     CDS             complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VUX16_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET8124237.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLVGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
     gene            complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VUX16_001276"
     CDS             complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VUX16_001276"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET8124238.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VUX16_001277"
     CDS             complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VUX16_001277"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET8124239.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3790..5058)
                     /locus_tag="VUX16_001278"
     CDS             complement(3790..5058)
                     /locus_tag="VUX16_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET8124240.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLLQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5178..5546)
                     /locus_tag="VUX16_001279"
     CDS             complement(5178..5546)
                     /locus_tag="VUX16_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET8124241.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5539..5805)
                     /locus_tag="VUX16_001280"
     CDS             complement(5539..5805)
                     /locus_tag="VUX16_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET8124242.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5863..9378)
                     /gene="mfd"
                     /locus_tag="VUX16_001281"
     CDS             complement(5863..9378)
                     /gene="mfd"
                     /locus_tag="VUX16_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET8124243.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTNTRTKGNAELILLIDAYLPDTYIS
                     DQRHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQ
                     RVERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDY
                     EILEGLLIFGESLLEIKESKEKNSI"
     gene            complement(9379..9948)
                     /locus_tag="VUX16_001282"
     CDS             complement(9379..9948)
                     /locus_tag="VUX16_001282"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET8124244.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10019..11134)
                     /gene="ychF"
                     /locus_tag="VUX16_001283"
     CDS             complement(10019..11134)
                     /gene="ychF"
                     /locus_tag="VUX16_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET8124245.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11254..12267)
                     /locus_tag="VUX16_001284"
     CDS             complement(11254..12267)
                     /locus_tag="VUX16_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET8124246.1"
                     /translation="MDFEKDGSTVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKF
                     KIDKYLLPAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYA
                     VSLQAIPFNPARDIIVPRRKEKKGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLY
                     KTLLATGLRIRECLALEWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSIRVIDLDNKT
                     VLMLRLYKARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFH
                     AFRHTHASILLNAGLPYKEIQTRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKL
                     KSS"
     gene            complement(12268..12420)
                     /locus_tag="VUX16_001285"
     CDS             complement(12268..12420)
                     /locus_tag="VUX16_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HET8124247.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQA"
     gene            complement(12516..12968)
                     /locus_tag="VUX16_001286"
     CDS             complement(12516..12968)
                     /locus_tag="VUX16_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET8124248.1"
                     /translation="MDKINYFSAEEAILLHDIEVIEKIGGLHGVKDKGRVFSVFEHLQ
                     NDDYYPDFETKLTVLVFNTVQFHMFNDGNKRSSIVFGIKFLTINHLDYLIPFFIETME
                     NIVLWVAMGLIDFNFLKEIISSILYYEELTEKVKEKLVQIALAEENNK"
     gene            complement(12968..13972)
                     /locus_tag="VUX16_001287"
     CDS             complement(12968..13972)
                     /locus_tag="VUX16_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET8124249.1"
                     /translation="MTDLTTSQIERQNILNNSLALQKAEEILKVPGFYFEDTFYFTNS
                     QLATFFEVDIRTIERLVEAHKTELTENGYHTLRGEKLAKFKENAFATDTNVGSKVTQL
                     SISSFRTLLNFAMLLTNSDIAKQVRNTLLDIVINVLTEKTGGHVKFINQRDKNYLSTA
                     LEEDNARKIFTNAIDKYVSGSNFKYGQLTNEIYKAIFKERASEYKKILKLNKNDNARA
                     TMYSEVLIVIASFEKGVAYEIEQKSKSSNQKLTNTDVIEIIQRLANHPMQEPHLMHAR
                     EKMASRDLSFRNAKHEKLAEYIRPISEEDFERFIGEQSKSLSEQIDEHRQVFERLRDK
                     "
     gene            complement(14121..15077)
                     /locus_tag="VUX16_001288"
     CDS             complement(14121..15077)
                     /locus_tag="VUX16_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8124250.1"
                     /translation="MAKNSPQDLENREYFSKRLNLLMEQKGVRQIDLHNALDIPKSTI
                     TGYVKGKSLPTAGNLQKIADFLNVKKSFLDLRFIDTVSTSTLKELLDNNQREKVFEMF
                     FNKIKEILSFKKDYMNMEYIRGKIAFDQGVLGRVLQSSIINPGIVEIFNGLDLSDISK
                     NNEALLLSKQREAREYAYNNVLTMITNEYITRLINVIEREQALNTSYVHSEISNLINS
                     LNNKIDSYGAVVFEVNEIIEKIGIQDRKILGYCLQRKISSVQNEINDLVHNNTNNSFC
                     VTKNKIFTEKSDIIDTIEFDYYKGIQNRLNDLAEEIREHFSD"
     gene            15192..15425
                     /locus_tag="VUX16_001289"
     CDS             15192..15425
                     /locus_tag="VUX16_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8124251.1"
                     /translation="MEQWTLKACRVNAGYTLRQIAKKVNKNFQTVSKYEKDSTYIPFE
                     LLKELSAIYQVKLDNIFLGDSTKKIELNKREVQ"
     gene            15515..16120
                     /locus_tag="VUX16_001290"
                     /pseudo
     CDS             15515..16120
                     /locus_tag="VUX16_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518114.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            16132..16392
                     /locus_tag="VUX16_001291"
     CDS             16132..16392
                     /locus_tag="VUX16_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124252.1"
                     /translation="MENEFKTVTNAKGLEIPKYPKDFKKLVEMDRQLAEYLCMNYENL
                     DNEDLGAFLETVEQGFSWILDLIESKDLLYSPQTGKKARKRQ"
     gene            16621..16791
                     /locus_tag="VUX16_001292"
     CDS             16621..16791
                     /locus_tag="VUX16_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124253.1"
                     /translation="MGKTLGRPKSDNPKNKQLKIKMTEQDFNNLEELAKKKNMTKTDI
                     VMRGIELVKSEP"
     gene            16946..17401
                     /locus_tag="VUX16_001293"
     CDS             16946..17401
                     /locus_tag="VUX16_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124254.1"
                     /translation="MRKKHQVVKFKDIAEKLPELEGKRLEEITKVLGYRNLESCRTNL
                     CKLKQNNRLDFTLEKGVYSKFALLDGTVKEELEDKELSERGRYLKSVDRYKAMLNAFS
                     IAFDSTVKAETRQKAEHDGLKALDRIPDKHYALLYDMMEGEDGSKNPLR"
     gene            17376..17525
                     /locus_tag="VUX16_001294"
     CDS             17376..17525
                     /locus_tag="VUX16_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124255.1"
                     /translation="MEAKTHFARFMRRGMELARQLHSKEIQRDEFDRAWKRLGDQIEN
                     ETKKN"
     gene            17959..18459
                     /locus_tag="VUX16_001295"
     CDS             17959..18459
                     /locus_tag="VUX16_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124256.1"
                     /translation="MISDKLEAISTNLEEIQKSLVGAETVLAKREISRVLNDLDDVYS
                     ELTSTEYHEQQQTIKEQTEKMKQRGIAEVIGELEEREESYYRNFWGDTQFIRLLSNFD
                     GFLFLNTYLAEITKENTYPMEQSQLLNYVWEVIAVDIAKKKRGKKNVLDSWTDSSLYT
                     RGMMID"
     gene            18471..18671
                     /locus_tag="VUX16_001296"
     CDS             18471..18671
                     /locus_tag="VUX16_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124257.1"
                     /translation="MTLDLGKMTQAEFDEVMADIKARNPNLLQLITDFLDRKVTPEEV
                     DDLLNMERAEQVEYIKNYQARA"
     gene            18673..18888
                     /locus_tag="VUX16_001297"
     CDS             18673..18888
                     /locus_tag="VUX16_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124258.1"
                     /translation="MNELDISNTHAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTI
                     KTPSEDLNPDYGRYIQLAGVRVSGGME"
     gene            18885..19178
                     /locus_tag="VUX16_001298"
     CDS             18885..19178
                     /locus_tag="VUX16_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124259.1"
                     /translation="MSYTMNLYPDIEKIPDEPYFTKDIFLATCMDNATKLAVTMSLLT
                     EQTLDLETETAILKTLDTIIETQKDILQGVASGQITFVNKSKGEEGLDESIRE"
     gene            19159..19500
                     /locus_tag="VUX16_001299"
     CDS             19159..19500
                     /locus_tag="VUX16_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET8124260.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKR
                     LVVKHNIPIVGVRCGVFSGYFIPANKGELLDGAKAFYNQVQEESKRLAVLMNSDLESY
                     KETLKEVGGYV"
     gene            19493..19768
                     /locus_tag="VUX16_001300"
     CDS             19493..19768
                     /locus_tag="VUX16_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124261.1"
                     /translation="MFSLSRESEHDLTHGILEVVERYLEAREKVPPRLTKLINRVELK
                     EELKISDNTLNKWESQGLRRYQPPDDGARIIFYLVDDIRRFMGVENG"
     gene            20180..20590
                     /locus_tag="VUX16_001301"
     CDS             20180..20590
                     /locus_tag="VUX16_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HET8124262.1"
                     /translation="MEAVSSALFGYSYILYPTIKQGLYLELAALESGIIKKQELSNTR
                     VQTSRVNTTENNLINVLKLKEYTLQRIERLTEERMEISRLIDKLANPLERSVLRLFYL
                     NVLDAWQVAEEIDKSKTAVYIIRQKAIEHLANVG"
     gene            20747..21139
                     /locus_tag="VUX16_001302"
     CDS             20747..21139
                     /locus_tag="VUX16_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET8124263.1"
                     /translation="MELDKFKTMMNVRERMTYFLRFQRMAGSENQVTIDEEAWKLVLP
                     DQWNLTSKHEKAIREGLEIFAQDINSIENKRARKYFIIHYCYMRKKTMSECVEMAATS
                     STSYHRYKQIAVLNFARIHQNGELEVYK"
     gene            21193..21339
                     /locus_tag="VUX16_001303"
     CDS             21193..21339
                     /locus_tag="VUX16_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124264.1"
                     /translation="MIEDFLIDLDNIQLEDMEIDFNMDIDIDLNIDFDLDGLDLTLLQ
                     ELEA"
     gene            complement(21770..21964)
                     /locus_tag="VUX16_001304"
     CDS             complement(21770..21964)
                     /locus_tag="VUX16_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET8124265.1"
                     /translation="MYQVGNFVEMKKPHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFDRKMNKIID"
     gene            complement(22029..23165)
                     /gene="dnaN"
                     /locus_tag="VUX16_001305"
     CDS             complement(22029..23165)
                     /gene="dnaN"
                     /locus_tag="VUX16_001305"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET8124266.1"
                     /translation="MMHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(23324..24685)
                     /gene="dnaA"
                     /locus_tag="VUX16_001306"
     CDS             complement(23324..24685)
                     /gene="dnaA"
                     /locus_tag="VUX16_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET8124267.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(24898..25656)
                     /locus_tag="VUX16_001307"
     CDS             complement(24898..25656)
                     /locus_tag="VUX16_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET8124268.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIHNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(25714..26895)
                     /locus_tag="VUX16_001308"
     CDS             complement(25714..26895)
                     /locus_tag="VUX16_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET8124269.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGEIAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLDKSSGDLE
                     S"
     gene            27078..27557
                     /gene="rlmH"
                     /locus_tag="VUX16_001309"
     CDS             27078..27557
                     /gene="rlmH"
                     /locus_tag="VUX16_001309"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET8124270.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     FTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            27601..27674
                     /locus_tag="VUX16_001310"
     tRNA            27601..27674
                     /locus_tag="VUX16_001310"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27635..27637,aa:Arg,seq:tct)
     gene            27839..27964
                     /gene="comC"
                     /locus_tag="VUX16_001311"
     CDS             27839..27964
                     /gene="comC"
                     /locus_tag="VUX16_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET8124271.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRISRIILDFLFLRKK"
     gene            27985..29310
                     /locus_tag="VUX16_001312"
     CDS             27985..29310
                     /locus_tag="VUX16_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET8124272.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYVFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            29307..30059
                     /locus_tag="VUX16_001313"
     CDS             29307..30059
                     /locus_tag="VUX16_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET8124273.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            30111..30182
                     /locus_tag="VUX16_001314"
     tRNA            30111..30182
                     /locus_tag="VUX16_001314"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30144..30146,aa:Glu,seq:ttc)
     gene            30188..30261
                     /locus_tag="VUX16_001315"
     tRNA            30188..30261
                     /locus_tag="VUX16_001315"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30222..30224,aa:Asn,seq:gtt)
     gene            complement(30302..30844)
                     /locus_tag="VUX16_001316"
     CDS             complement(30302..30844)
                     /locus_tag="VUX16_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET8124274.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKARISRS
                     SFYTHYKDKYDMIEYYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSIDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            30952..32552
                     /locus_tag="VUX16_001317"
                     /pseudo
     CDS             30952..32552
                     /locus_tag="VUX16_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
BASE COUNT        10365 a         5806 c         5723 g        10673 t
ORIGIN      
        1 tttcgtcatt catttttgac tttacttcat cataggatag tgcatgagat tcctcttcta
       61 ctgcttcagg catctttcct gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt
      121 cgtatttcaa taatgcttct gcaattaact tgtgagtttc acgatttgac tgaataattt
      181 cagcagcttt atttcgtgcc tcatttaata atgaacgaac ctcttcatca atttcataag
      241 ctgtttgttc tgaaattgat ttttgaggac tctgtgcacc aagcatagca tggtttcctt
      301 catattgtac tgggccaagt ttttcactca taccgtactc tgtaaccatt gcacgtgcca
      361 tttgtgtcgc ttgttcaaag tcgtttgaag ctcctgtagt ttggacatta aagataattt
      421 cttcagctac acgtccaccc attaagccaa ccaattgctc tttcatatct tctttagata
      481 gaagcatttg atcctcttta ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta
      541 caattgtaac cttatggaca acgcgagcat tcgacaagac tagaccaaca atggtatgtc
      601 ctgcctcatg gtaagcaacc aattctcgtt ctttttgtga aactgtctta tctttcttag
      661 aaggtccagc aataactcta tcttctgctt catcaatatc tgaagcatca attatcgatt
      721 tattgcgacg agcagcaact aaagctgctt cattcaagac attctctaaa tcagcaccaa
      781 caaagcctgg agtttgttga gccactaatt tcaaatcaac atcttctgct aaaggcttgt
      841 tcttagcgtg aactttcaag attgcttcac gacctttaac atcaggacgg ccaaccaata
      901 cttttctatc aaaacgtcct ggacgcaaaa gggcaggatc aagtacatct gaacggtttg
      961 tcgcagcgat gacgataatc ccttcatttc cctcaaaacc atccatctca atcaaaagtt
     1021 ggttcaaggt ttgttcacgt tcgtcattac ctccgccgag accgactcca cgttgacgtc
     1081 caacagcatc aatttcatcg ataaagatga tagctggtgc tgcttttttg gcatcctcaa
     1141 aaagagagcg aacacgacta gctccaactc cgacaaacat ttctacaaag tcagaacctg
     1201 agatactaaa gaatggaaca cctgcttctc cagcgactgc cttagcaagc aaagtcttac
     1261 ctgtccccgg aggtccctcc aaaagaacac ctgctggaat acgggctcca agttttgtga
     1321 atcgttttgg atcttttaag aactcaacaa cttcaactag ttcttgtttt tcttcctcag
     1381 ctccagcaac atctgaaaat cttactttaa tatcttcttt atttgctgct ttagccttac
     1441 tacgtccaaa actcattgga ttacggccat tgcctcctcc catatttccc atcatagaga
     1501 ataggaagaa gaatagaatt ccaaatggca caatggatac gagtagatta atccatatac
     1561 cacttgaact ttcatgctta acagttactt ctgctttatg gtcagtagca agtttttgca
     1621 attctgatac ggtagtatct gcaggaagaa tagtgctggt aaatttctct accttagtaa
     1681 cagatggcgt gaaaaactga atacctgttc cttctttact tgttttagga tttttataga
     1741 caccagaaac ttcgataaca ctaccatttg gttggtaagt taattctttt acattaccat
     1801 cggtaatttc ttgtaccaac tcagtatagt tgatttgctg acttcctcct gagttattcc
     1861 cagaatagaa atactggaat cctgtcacaa ggaaaaagat aaataataac catagaaaag
     1921 gatttttaat taaaccatta ttttgttttt tcattaaaga ttattctttc taatttgaat
     1981 acacttcctc tttcaatact ccaatataag gaagattacg ataattttct ttgtagtcta
     2041 aaccataacc tactacaaac tcatttggga tagtaaagca ggtatagtct gcctcaattt
     2101 ctacaacacg tccttctggt ttatccaaca aggttgcaat tttaacagaa gctgcttctc
     2161 tttctttaaa catatctcgc aaattcttca aagtttgacc tgtatcaatg atatcttcta
     2221 caaatagaac atgtcttcct ttgatatctt gagtcacatc ttgtttaata ttgataacac
     2281 cactacttgc tgttccacca tggtagctag aaaccatcat gaagtccatt tcaatatgtg
     2341 tatcaatatg tttgaccaat tcagccataa aaggaataga tccttttaaa atcccaacta
     2401 agattggatt ttttcctgca tagtctttag ttaattgagc acctagtttt ttagctgctt
     2461 ctgtaatttc atcgtgtgaa acgaggactt ttttaatatc gttttctaac attttttacc
     2521 tatctatttt ttctatataa agtacagtgt tcattatatc atttttcgtt tttttactca
     2581 aattattggt cgcaattccc aaaattgaga caatttcacc aaattgctca ataataagag
     2641 cagagtttct cttttccata gggattttca aatcaataaa taaacgtctg agtttttttc
     2701 tatgcccatt ttgaatcaaa acatctcctg tttttcgatg acgaatgtgt atggatgttt
     2761 cacgtgaaac aggtatttgt tgaattgatt caccttctaa tggaagtcca aaggaaaata
     2821 aatatccttg ataagctacc tgattttgat agtgtaacac aagttcatct tcctcttcat
     2881 cagcctgcgg actgatttta caaatctgaa actgttggta ctcttttatc aattcatagc
     2941 catttttaat cggatgacga tactggcttt tagattttaa aatctgctga acttcagcaa
     3001 actgagcttt tgtaagattc aaatctggaa aacgattcag ataagtttga agtaaaactc
     3061 tttgtgtaga ctcagagtaa gaaaataact gctgtaaatt ttccacatta atattgttag
     3121 ataattcagc tattgccaaa tcataatcta aaatttcatt gccgatgcct aagattgcat
     3181 ccctaaatcg aggattttct ttttccaatt ctggtaagta agaatttcga atacgatttc
     3241 gaaaataatg attctcctga tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt
     3301 ttttctgaaa atgcaagaag ggacgaatga tttctatctc tccgactact tgcttctcct
     3361 taattcctga tagatagcgc aagcgagttc ctcgaatcaa gcgcatcaaa atcgtttcca
     3421 cctgatcatc agcatggtgg gcagtgacta aagctgtcgc acctgtcttt ttcatgacct
     3481 cttgaaaaaa atcataacga aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat
     3541 tgctgatata aataggaagc tctgcttcag cagccaactt ccttaattcc ttttcttccc
     3601 aatctgattc aattctctgc ttatgattca catgagctag aatcaattca atctctaact
     3661 ctttttgata agtagacaat accttaaata gaaacatgga atctaatcca ccagaaagag
     3721 ctagaaccgc cttagcatgc tttttgaaat atcccttctt gagaaaatga tttaaaaaat
     3781 ctggttccct cattttagaa cctcataaac atccttggct atcttagaaa tcgtatcata
     3841 atcagaattc ttagtgaaaa tagaaagaat aaatggagaa tctgcataga caacacccgt
     3901 atcatgctta aattcatccg catctccaat tttatgagct actttaacag aaacaccttt
     3961 ggcaattcgc tgactatcaa aatctgtttt agtcaaagac tctagcacaa atccattttg
     4021 attataaata gcttccataa acttcccggc catcttagaa gaaatcaatt tttcttttgg
     4081 atcccaatca tctcccataa tggcagacat cttggatttg aatgtggcat cagattggtt
     4141 tgaaatgtaa tatcccaata gattatgagc tacattatca gattcttttg atactttcgt
     4201 aattaaatcc tttaaagaat attctttatt atcttctttt ttaggaagac taccacttcc
     4261 ctctggttta taagaacctg gaaaatcatt gactgcagat acgtatttta cagtcgtatc
     4321 taactgataa agaccctcat ttattttttc ttgcgtataa tagagatagg agagtttcaa
     4381 aacgctggct gcatacatct tttcatcttg attgatacca gcttcttttc cagtagtcag
     4441 ttgcttaaca taaatagaga aagaatcttt ctgatatttt tcagataaca tttcttgaac
     4501 tttactcatc cgattatctt cttcagaagt tgattcttta gctacccatc cagcctgatc
     4561 aatatgtaga aattctcttc cttctacaaa catggtcttg tcgattgata cttgcgaata
     4621 agctgataag gatgatttca cttcttttaa atcataagga ctattgtaca gtttaaagtc
     4681 agattctaac catgcttttt ttattgttgg agttacctct gattgatcat ataaaaatcg
     4741 tttgtccgca gctataaatt gatgatttga tagcttaaat actggaattc cttgtttatt
     4801 taagcgccac tcggttattt gaaaacttgt tttgggagtc aatttcccag attccactac
     4861 taaatcttca ttcgcataaa caggaacctc tccataaacc atgggagaac ttaatttttc
     4921 tctaaaataa ataccaaagt cagattgtaa aaggtaataa atttctttcg aagtatagac
     4981 gacttctttt tctgtgctaa cgacttttga aatggtcaaa aaacttggta gcaacaaaat
     5041 aattaagaat ttacgcattc ttcctttcct tttcttcttg taaacgcaat aattgatttt
     5101 tatcagccaa ttcttccagc ttttcatctg acaaactcaa aaattgctct attacgtcta
     5161 ataaattttc cattttatca cctttgaagc aagtcaggaa tcgtataaac tttttccctc
     5221 gacttagaat aatagtactt cgctcgtgta tatttagcag cataatcttc atctttcaac
     5281 ttggtagcaa atgctgtctc cttatccttt tcatcactca aagtttgata ctgagtttgc
     5341 aagtctgcta attgctgacg tctttggagt aattgctgat aactctgcgc taaattaaaa
     5401 gttggcaaga taaataatag cataatcaaa atcaataccc ctcccataaa acgattccgt
     5461 ttttgtcgtt ctttcatcag gtagcgacga cgttggtatt cattttgaat aaaagaatta
     5521 ttcaattgta caatattttt agacattttc ttctacccgt gtttcactga taatttcata
     5581 cattcctgct gcatcttctt tttttgtact atctttcatc tctagtactt ttacaagcag
     5641 caacttattg ccaaagcgaa tttcaacttg gtcattaact ttcaagtccg ttgaactttt
     5701 ggccaagatt ccattaacct tgattctacc tttatctgct acttcctttg cgactgtacg
     5761 acgcttgata attcgcgata cttttaaata tttatctaat ctcatcctta ttacctcaat
     5821 ttattattgt accattttta tcttttttat agaagaaaaa tatcaaatgg aatttttttc
     5881 cttagactct tttatctcta ataaactttc tccaaaaatc agcagacctt ctaaaatttc
     5941 ataatctttc ttattttgga catcaaatac aagctccatt aatcccttat tctcagcgat
     6001 gcctgctttt aagttcgtta cggataaagc tttaaaataa tcttgagcta aaaacaatcg
     6061 ttgagtgact ttttcaaatt gaattgtaat tttattatct tttctttcca cacgttgaac
     6121 aaagaccttg tccaagtatg atttgaccaa accaatctct aaaagatagg ctactacatc
     6181 tgggtattct ccaaaacggt ctatcaactc ctcttgtaac tcttcataat tgacacggtt
     6241 gtcaatttga cgaattttct tgtaaatttc aatcttatgt cgttgatcag aaatataagt
     6301 atcaggaaga taggcatcaa ttagcaaaat caactcagca ttccctttgg ttcttgtgtt
     6361 agtgttagcg ttagcattac cgtttcgttt agcaatagct tcctctaata actgcgaata
     6421 caattcaaaa ccaacagaat caatgaaacc agactgggat tttcctaaaa gatttcctgc
     6481 tccacgaatc gaaagatctc gcattgcaat cttaaagcca gagcccaatt ctgtaaatcc
     6541 tttaatcgct tctaatctct tttcagagac ttcactgatt gatttttctg gacgatacat
     6601 gagataagca taagcaatac gattactacg accgactctt cctcttaact gatataaggt
     6661 tgacaagccc atatggtccg cattttcaat aaataaagta ttagcatttg gaatgtccac
     6721 ccctgtctca ataatagtag tcgtcaccaa gatatcgtat tgtccctcaa taaagtctaa
     6781 tagagtattt tccaactgga cttcactcat tcgaccatga acatatccaa tcgaagcctc
     6841 cggaatcaac tcctgtaatt ctgaaacctt ctgaacaatt gtgtcaactt tgttgtaaag
     6901 atagtaaact tgacctccac gctccatttc acgcaagaca gcatcacgaa tgacactatc
     6961 attcttttcc aaaacatagg tctgaacagg atagcgatta gtcggcggag tttcaataac
     7021 agataaatct ctgattccca gcatagacat atggagggta cgagggattg gcgtagcggt
     7081 caaggttagg acatccactt gtttcttcag ttctttcaaa gtttccttat gcttgacacc
     7141 aaatcgctgt tcctcatcaa taatcatcaa gcccaaatca gcaaacacaa catcttttga
     7201 caaaacacga tgtgttccaa tcaaaatatc gacttgaccg tttttcaatt tttcaagtgt
     7261 tgcagtctgc tcttttttac ttctaaagcg actcaacaca tcaacattaa ctgcaaaatt
     7321 ttggaatcgt tccttaaaat tcgtatagtg ctgttgcgct aaaaccgtcg tcggaactag
     7381 aatgacaacc tgtttgtgat cattgactgc tttaaaggct gcacgcatag caacttcagt
     7441 ctttccaaaa ccaacatccc caactaaaag tcgatccatt ggctgagaag cctgcatatc
     7501 cctcttgatt tcctcaatac tacgaagttg atcatccgtt tcaacataag ggaaagcatc
     7561 atcaaaggca tcttgatcat catcatcagc tgagaaagca aaacccttca actgactacg
     7621 ttcagagtag agtttgatta aatcatcagc tatatcctct acctggttct taaccttttg
     7681 cttggccttt ttaaaatgac cgtcatttaa tttattgagt tttggagctt taccatcact
     7741 tgaaatatat ttggacagta gatgaatctg ttccacgggg atagaaattt gatcaccatt
     7801 ttggtattgg acactgacat aatcgcgatg aattcccttg atttcaatgg tttcaattcc
     7861 tagatattga ccaatcccat ggatatgatg gacaacatag tccccttttt caagttcatt
     7921 gtaatctttt aatctctctg catttgaaac atgttgtctt cgaaaacgac gctttaattt
     7981 cttttgaaaa atctcatgtt cagttatcaa taaaatcttt tcatctacaa aatgaaaacc
     8041 atgtctgaga ttaccctcta ttaagtttac agattcttta cagatacttg tcttatctct
     8101 agaatccaat ttaatctgat attcctctaa catatcctcc aatgttttac ttcccattga
     8161 attgctagac tgcagaataa tggtgtaatc cattttttta tatcgttcaa tttcttcttt
     8221 tagaaaagaa aactgattga aaaattcctg cataggatat tgattgaatt gataaatttt
     8281 gtcaaatttg agatttccta aacccttttg aagattagag aaaaaggtca ctggactttg
     8341 ttttttatag atttgttcaa tatcagaaaa atactgcata tcagaaaatg ctttactatt
     8401 ctgtaattct tctgtaaagt actgcgctaa gtctctttca aagacttcat actgattcat
     8461 caatttttga taatcatcaa agaatattgg agtatctttt tcaatataat caaagacagt
     8521 ccatgtctta tcatagcaca aagataaaaa cttccgagag tctgcatgac tttgtttttg
     8581 gtgaaaactt gaaagaattt cttccaggta tgatttcaaa ataggtgata aagtttttga
     8641 aatttgtttt tctaaagctg actgtcctcg ttgataatcc ttttctctca aaagcatatc
     8701 actagctgga aagatagtga gttctgtctt attttctttc gataattgtg tttctacttc
     8761 aaatgacctg ataccatcaa tttcatcacc aaaaaactca attcgacaag gttctaactg
     8821 ggatatttca aaaatatcta aaatatctcc tcgaagacta aattcgccct gagtttgtac
     8881 ttgagtaact tttcgatagc cattttcctt taactgatgg ataaacgcgt gttgatcata
     8941 ttcttcacca actgagattt ttacaatact atctttgaat gcattgggag acggtaaaat
     9001 caatcgactt gctgcgatat tacaaactaa aatccctttc ttagatgaat cagtcaaaaa
     9061 acgcaaggct tcaacccgtg aaataatttt ttcctgtgaa gacatcaaaa actccaccat
     9121 aggagcatca tctaccaaaa atggatagac gagttcctca cccaagatag atataagatc
     9181 actaacaagt ccttctgctt ctccataagt tgacgtcaat aacacaatcc tatcttcttt
     9241 ttctaaactg cttgcaattg caagagcctt agtagatgtt gataaaccaa gtattagttg
     9301 tcttttctta tctgttaaat tttgatgcca ttttttaatc tgatcatttt ctgagaataa
     9361 atctaataag gtcaccattt atccgttata cctctgcatt gttttctcaa aatttttctc
     9421 ttgtaaatag tagtttacag aatcgtcaac tttgtcaaca gactgtaaaa taccgatata
     9481 atcatccctg tcaaacttac tcaaaacatg atgaacaact gacataccat ttttaggtct
     9541 tccaattcca atcttaacac ggttaaagac ctgagttcct atatgttgaa taatagactt
     9601 gataccatta tgaccacctg ctgagccttt tgctcttaaa cgaattttcc caacttccat
     9661 gtcaagatca tcgtaaatga taagtaaatc gtcaatatcc aaaccatagt aagttaataa
     9721 agcatgaact gcttttccac tttcattcat aaaggtcgtt ggtttaacca gataaatttt
     9781 ttctccattt aggaaaaagg atgctaggtc agcttgaaat atcttatcgt gtgtaaaagt
     9841 gacattctgt ttcttcgcta gttgatcaat caacataaaa ccaacattgt gttttgtttc
     9901 aaaatattta tcccctggat ttcccaagcc tacaagtaat ttggtcattt atttttcctt
     9961 tcaaaagcca aaagggttgg aatttttttc caacctaatt gacaccattt attaattttt
    10021 agacattaaa gcggaattcc atgatatcgc catcttgaac gatatattct tttccttctt
    10081 cacgcaagcg tccagcttct tttacggcct tttcagattc gtatttcact agatcctcat
    10141 atgacatggt tactgcacga ataaagcctt tttcaaagtc tgagtggata ataccagctg
    10201 cttgaggagc cttcatacca cgtttgaaag tccaagcgcg aacttctttt tcaccagctg
    10261 tgaagtaagt tcccaatcca agcaagtggt aagctgcacg cgtcaactta tctacacctg
    10321 attctatcaa accaatggct tcaagaaact cttttttatc ttcatcatcc aattcagaaa
    10381 tttcttcctc agcacgcgca gaaataacga ctacttcagc attttctgtc gctgcaaatt
    10441 cacgaatttg tttgacatag tcgatagagt caggttctga aaccacatcc tcgtccacat
    10501 tagctacata aagaactggt ttagtcgtca aaaggaaaag acctttgaca accttttgtt
    10561 cctcatctgt aaattcaatg gtacgagctg atttcccgtc ttctaggact ggtttaatct
    10621 tttgaagaac attgaattct gctactgatt ctttatcttt ttgcgtacgt gccatctttt
    10681 ctacacgcgc atatcgttta ttgactgatt ctaagtctgc aagaatcaat tctaggttaa
    10741 tggtgtcaat atctgcaagt ggatccacaa aggcgtcttc acgtccttgc tcgcgcatta
    10801 cattttcatc atcaaaagca cgaactacgt gaacaatcgc atctacttca cgaatattgg
    10861 ccaagaattt attccctagc ccttctcctt ttgaagctcc ttttacaatc cctgcaatat
    10921 ctgtaaattc aaatgttgtg ggaactgtct ttttaggagt tatcatttca gttagttttt
    10981 gtaggcgttc atctggaact tccaccattc caacatttgg atcaatcgtc gcaaatgggt
    11041 agtttgctgc ctctgctcct gcttttgtaa ttgcattaaa tagtgttgat ttaccaacgt
    11101 ttggcaaacc aacgatacct gctgtcaaag ccatatttct cattctccgt tttcatttca
    11161 atccctaata ttataacaca aaaaggggaa acttgctaaa attccttgat atagctattt
    11221 cccataactg aaataataat tttatggact tttttaggaa ctttttaatt tttcaatagc
    11281 tttttcataa aatgaagtag catttttctg attgtctttg gataggtggc tataaatatc
    11341 catggtcata gaaagttttg catgaccgag ccgtgtttgt atctctttgt aaggtagtcc
    11401 agcattgagc aagatactag catgagtgtg gcggaaggcg tggaacgtaa aacgagggca
    11461 tccagcccgt tccaaatgtt ttactaacct gaaactaagc attctagcgt ctatatgctt
    11521 atcaaagcta ttagagaata ctttctcata ggtcaacccc atttctttcc ctatttggga
    11581 ttgtcttgct ttatagagcc gtagcatgag caccgtctta ttatccaagt caattaccct
    11641 aatacttgat ttagtcttag ggccagtgat ttctttgata atatttaacg ttttatttac
    11701 gtctagtgtg ccgtttttta ggtcaatatc agaccactct aaggctagac actcacgaat
    11761 gcgcaaacca gtcgctaaaa gcgtcttata tagcaccgta tcgtagaaat ttttgtaagt
    11821 gtttggcagc tgctccaggt aagtcaagaa tttttttaag ttatcatcat ccagatattt
    11881 cagtttttgc cctttttttt ccttacgacg tggcacgata atatcacggg cagggttgaa
    11941 ggggatagct tgcaaagata cggcatattt aagtatgcgt ttgtttagcg agtgaaggag
    12001 aggatactct tgaaaccctt tgcctagttg attatagtct tttgcccatt gattgacttg
    12061 cttttgaatg attgggggcg tcagtttatc cagcctataa tttccgaaag ctggaagtag
    12121 atatttatct attttgaatt tggtacccat taaggtcgat tttttaaccg tatggcagta
    12181 ggtttctagc caattctcca ccagttcggc gtaagtcttt atctcaactg ctttatatac
    12241 tgtagacccg tctttttcaa agtcgattta agcctgtagc gctttggctt tgagttctct
    12301 cttggttcgc cctgatatag tcgtcttgac tttcttacct gttacggtat cgataccaag
    12361 gtagacgcta gagcgataga ctgtagaccc gtcttttttg gtgtattctg ttattttcat
    12421 gatgataaac ctttctaaaa tacatcagca ggcaagctat tattaaaaag gttttagatt
    12481 atggtttata tcatgttgag cttacgggaa agattttatt tgttattttc ttcagctaaa
    12541 gctatctgta caagtttttc ttttactttt tcagtgagtt cctcatagta gagaattgaa
    12601 gaaataattt cttttaaaaa attgaaatcg attaacccca ttgctaccca taagacaata
    12661 ttttccattg tttcgataaa gaagggaatg aggtaatcaa ggtgattgat tgttaaaaat
    12721 ttaataccga agacaatgct acttctctta tttccatcat tgaacatatg aaattgaact
    12781 gtattaaata ctagcactgt aagttttgtt tcaaagtctg gatagtaatc gtcattctgt
    12841 aagtgttcaa atacactaaa tacccttccc ttatctttaa caccgtgtaa accacctatt
    12901 ttctcaatta cttcaatgtc gtgtagtaaa attgcttctt cagcagaaaa ataattgatt
    12961 ttatccatta tttatctctc aatctttcaa aaacttggcg gtgttcatca atttgttccg
    13021 aaagtgattt actttgttcg ccaataaatc tttcaaaatc ttcttcagaa attggacgga
    13081 tatattctgc taatttctca tgtttggcat tcctgaaaga tagatcccta ctagccattt
    13141 tctctctggc atgcattaaa tggggttctt gcattgggtg atttgctaat ctctgaatta
    13201 tctcgattac atcagtatta gttagttttt gatttgaaga cttactcttt tgttcaatct
    13261 cataagcaac ccctttttca aaactagcaa taactataag tacctcacta tacattgttg
    13321 cgcgagcatt atcattttta ttcaatttca gtattttttt atattctgat gctctttctt
    13381 taaagattgc tttgtaaatt tcattcgtta attgaccata tttaaaatta cttccagaga
    13441 catacttatc aatggcattt gtaaatattt ttctagcatt atcttcttct aatgcagtcg
    13501 atagataatt tttgtcacgc tggtttataa attttacatg gccaccagtc ttctcagtta
    13561 acacattaat gacaatatca agtagggtat ttcttacttg cttagctata tcactattgg
    13621 ttaacaacat agcaaaatta agcaatgttc tgaacgatga gatacttaat tgtgtaactt
    13681 tgctaccgac atttgtgtcg gtagcaaaag cattttcttt aaatttagct agtttttctc
    13741 cacgtaaagt gtgataacca ttttcagtaa gctccgtttt atgagcttca acaagtcttt
    13801 caatagttcg aatgtcgact tcgaaaaagg tagctagctg agaatttgta aaataaaaag
    13861 tatcctcaaa gtagaaacca ggtactttta aaatctcttc agctttttgt aatgctaaag
    13921 aattatttaa aatattttgt ctttctattt gtgaggttgt cagatcagtc ataatttctc
    13981 ctttttgtcg agttaatttg ccaataactc ccgatatttc aagagtttta ttttattttc
    14041 gtgtcgttag agtatattag aaaatcttga actccgcgaa tacacgcgct tcaggattgt
    14101 tgaacattgt ggcgcgtggg ttagtcgctg aagtgttccc tgatttcttc agctaaatca
    14161 ttcaagcggt tctgaatacc tttatagtaa tcaaattcaa tggtgtcaat gatgtcactt
    14221 ttttcagtaa atatcttgtt ttttgtaaca caaaagctat tatttgtatt attgtgaaca
    14281 aggtcattta tctcattttg aacagaagat attttccttt gtaagcaata gcctaagatt
    14341 tttcgatctt gaatacctat tttttcaatt atttcattca cttcaaagac aactgcccca
    14401 tagctatcaa ttttattgtt aaggctattg ataagattag aaatttcaga atgcacatag
    14461 gaggtattga gagcttgctc acgttcaata acgtttatta aacgtgtaat atattcgtta
    14521 gtaatcatgg tgagtacatt attataagcg tactccctag cttcgcgctg tttggaaagt
    14581 agtagagcct cattattttt tgagatatct gataaatcaa gtccgttgaa aatttcaaca
    14641 ataccagggt ttattattga agactgaaga acgcgaccca aaacaccctg gtcaaatgct
    14701 atttttcctc gaatgtactc catattcata taatcttttt taaagctaag tatttctttg
    14761 attttattga agaacatctc aaaaaccttt tctctttgat tattatctag caactctttt
    14821 agtgtgctgg ttgaaactgt atcaataaac cgcagatcta ggaaagattt ttttacgttc
    14881 aaaaaatcag ctattttttg taaattccca gcggttggta aagattttcc ttttacatat
    14941 cccgtaattg tacttttagg aatatctaaa gcgttatgaa ggtcaatttg tctaacccct
    15001 ttttgttcca taagaaggtt gagccgttta gagaagtatt ctctattttc aagatcttga
    15061 ggactatttt tagccatgac tttaaccctt tcagttgtaa gttatacatt gattataaca
    15121 caaaataaaa acaaagtacg aaaataatag tactattaac ttatcacttt tgaaaggaat
    15181 tgttagatta tatggaacaa tggacgttga aagcctgtag agtaaacgct ggttatactt
    15241 tgcgacagat tgctaaaaag gtaaataaga attttcaaac tgtctccaag tacgaaaaag
    15301 atagtacata tataccgttt gaacttttaa aagaattgtc tgcaatttac caagttaaat
    15361 tggacaatat ttttttagga gacagtacga aaaaaataga actaaataaa agagaggtgc
    15421 aataatgaga gtattatttt aagtcaatgg tggcagaaat caaaccagac ataacaatag
    15481 atgaattatt ttatagctag aaaggagcaa accaatggaa ctagtctaca tggacggaaa
    15541 gaaagagccg tatactacga gtgagatcat cgctgaatgt gctggagtca ctcatcacac
    15601 aatacaagaa cttttaagga agcataaagc tgattttgaa agctacggaa ttatcgcatt
    15661 tgaaatgcga taattagacg gccgagggag accaatgaaa atatatctcc taaatgaaca
    15721 acaagcgacc ttgctgatca cttatttaaa gaatactgaa cctgtacggc ggttcaaaat
    15781 gaacctagtc aaagcattct ttgaaatgcg tgaggagctt tctaaacgct atcttcaaag
    15841 agaactggaa aagccaaagc gcaagacctt aaccgaagct atcaaatcat gggagaaagc
    15901 gcccaagcat gcctatagta cacttacaaa cctactgcta aagggagcga ctgggaaaaa
    15961 caaagcccaa ctcatgcaag agcgagaaag tgaaaacggt attgacagtt taacaagcgc
    16021 ggaactgaca aactaccaac gtttggaaga tatggcaata gcgatgatta acttgaatag
    16081 ggtgtattca gaaattgaag aactaatttt taaagcatag gagtatagaa aatggaaaat
    16141 gaatttaaga cagttacaaa tgccaaaggg ttagaaattc ctaagtatcc caaggatttt
    16201 aaaaagctag ttgagatgga cagacaacta gccgaatatc tttgtatgaa ctatgagaac
    16261 ttggacaatg aagacctagg cgcatttctt gaaacggtgg agcagggatt cagctggatt
    16321 ctggatctta tcgaaagtaa agatttgctt tatagccccc agacagggaa gaaagcaaga
    16381 aaaagacaat aaaaaaagtc acttgctgat agtttggcga ccgaggcaag cgacaagatt
    16441 tagggtatag atattttttc tatacctaga ttatagcata atatagcggt ttccgctagt
    16501 acattgaaaa taaaataagg tacgctggga agattttaaa tttttttcgg tttaggggtt
    16561 gacttaaagg gtacaccgtt acataataaa agggtacccc gaaagaaaga gaggtcaaaa
    16621 atggggaaaa cattaggacg acctaaaagc gataacccaa aaaacaagca actaaaaatt
    16681 aaaatgactg aacaggattt taataattta gaagaacttg ccaaaaagaa aaacatgact
    16741 aaaacagata tagtcatgcg agggattgag cttgtaaagt ctgaaccata acgaaaccgc
    16801 ctaccgtgtc acttgtttgg cgacagaaca cgatagacgg cgatgcacca caaatgaggt
    16861 acgtaaatat cttatcatgc gtactcttat ttgtcaaaca tagaaataga gtacgctttt
    16921 tgcgtaccca aaaatgaggt atacaatgag aaagaaacat caagtagtaa aatttaaaga
    16981 tattgctgaa aaattgcctg aattagaggg caagcgccta gaagaaatta ctaaagtatt
    17041 aggttaccgt aacctagaga gttgcagaac caacctctgc aagttgaaac aaaacaatcg
    17101 cctagatttt acactagaaa aaggagttta tagcaagttc gcactattag acggtacggt
    17161 aaaagaggaa ttggaagata aagaattgtc agaacgtggg cgctatttga agagtgtaga
    17221 ccgctacaag gcaatgctga atgctttttc tatcgccttt gatagtacgg tcaaggcgga
    17281 aaccagacaa aaagcagaac acgacggctt gaaagccttg gacagaatcc cagataaaca
    17341 ttacgcccta ctttatgaca tgatggaggg ggaggatgga agcaaaaacc cacttcgcta
    17401 gattcatgcg tagaggcatg gagttagcaa ggcaattaca tagtaaagaa attcaacgtg
    17461 atgaatttga tagagcctgg aaaagattag gcgatcaaat cgaaaacgaa acgaagaaaa
    17521 actaagaaaa ccgaagagca ggcaagcaat tagaaaaggt tttgaaaagc atagagcgcc
    17581 aactctttaa actggtactt tctcacgctt tcaatttggc gagtctgagc gtgaggcatg
    17641 tgacaggaaa aactgtataa gaaacaacca ttcaaaatcc ccacactcaa attttggcca
    17701 aggagagcgt gaggatagca attacaagaa aaaagcatta agaagccatc agggcaatta
    17761 caagaaaaaa gcattaagaa gccatcaggg caattacaca acatagaaac agaggtacaa
    17821 gtatggaaga aacaacatac gatattatcg ctaaaagctt ggatagaatt agtatggaat
    17881 tacaccaagc tgacgaaaat aacgattttc tagaatatgg gttttatcag gacaattaaa
    17941 aggccaatgg aggaaaacat gatatcagat aaattagaag ctatttcaac aaatttagaa
    18001 gaaatacaaa aaagccttgt aggggctgaa actgtattag ctaaaagaga aatcagtaga
    18061 gtgttgaacg acttggatga tgtttacagt gaactaacta gcacagaata ccatgaacaa
    18121 cagcaaacga taaaggaaca aacagaaaag atgaaacaga gggggattgc tgaggtaata
    18181 ggtgaactag aagaacgaga agagtcttat tacagaaatt tttggggtga tactcagttt
    18241 ataaggctac tttccaactt tgatggattt cttttcttaa acacttacct agctgaaata
    18301 actaaagaaa atacctaccc aatggaacaa agtcaattat tgaattatgt atgggaagtc
    18361 atagcggttg atatcgcaaa gaaaaaacga ggaaaaaaga acgttttgga ttcatggaca
    18421 gattcatcct tatatactcg tggaatgatg attgattagg aggcaatgca gtgacactag
    18481 acctaggcaa aatgacacaa gcagaatttg atgaagtaat ggctgacatc aaggcaagaa
    18541 atccaaacct attacagctc atcactgatt ttttagatag aaaggtaaca cccgaagagg
    18601 tggacgactt gttgaatatg gagcgagctg aacaagtgga atatattaag aattatcaag
    18661 cgagggcata acatgaatga actagatata agtaacacac atgctgctgt cttaatcgtg
    18721 attttgattg gcttactgct ttatttaaac caccgagacc gcaaaaaaag cgcccaaatt
    18781 gagcgagaaa accaacagac gataaaaaca cctagcgagg atttaaaccc tgattatggg
    18841 cgatatatcc agcttgcagg ggtaagagtt tccggaggga tggaatgagt tacacaatga
    18901 atttataccc cgatattgaa aaaataccag atgaacctta ttttactaaa gatatttttc
    18961 tagctacgtg tatggacaat gcaacaaagt tagctgtaac tatgagcttg ttgacagaac
    19021 aaacgttgga tttagagact gagacagcta ttttgaaaac cttggataca atcatagaaa
    19081 ctcaaaaaga tattttgcaa ggggtagcga gcggacaaat aacctttgta aataaaagca
    19141 aaggagagga ggggttggat gagtctatca gagaatgaca agcgagtttt aagactaatc
    19201 aaggtagggg ctgagaactc cataacaggg tcagaaatta gcctgacaac caagctaact
    19261 gaaagaactg tacgtgacat tatcaagcgt ctagtagtta agcacaacat ccctattgta
    19321 ggggttagat gtggcgtttt tagtgggtac tttattccag cgaataaagg cgagttacta
    19381 gatggcgcta aggcttttta caaccaagta caggaggaga gcaagcgcct agcggtgttg
    19441 atgaatagcg acctagaaag ctacaaagaa accttgaagg aggtgggcgg atatgtttag
    19501 cttaagccga gaaagtgagc atgatttgac gcatggcatt ctggaggtag tggaaagata
    19561 cctggaagcg cgtgagaaag taccgccaag attgaccaag ttaataaata gagttgaact
    19621 caaagaagag ttaaaaatta gtgacaacac gctgaataag tgggaaagtc agggtttaag
    19681 acgctatcaa ccaccggacg atggtgctag aataatattt tatttagtgg atgacattcg
    19741 taggtttatg ggggtggaga atgggtagat ataacacaca cccagcgcaa ggcggaggtc
    19801 attatcatga cattaaattg tataagcacc gtggcagatc tttggaacag ttccaagaac
    19861 aaaagctact gaagaagtta aaaaaaacgc aaaaaggggc gatagtatga caatttatga
    19921 ggctagaggt ttccagagta atcttgtcta tccatttgat aagatggagc cgttccagta
    19981 cattgaacgc tttaagcctt tggtagtccc tgaaggggca aacattgaag aatttaaacg
    20041 tatacaagcg ccttactgta ttagtggcaa agtgacacca gaaaagaatg gcagttacaa
    20101 gcgaaacaac accagtctaa tctatcggga tttgattttc cttgattatg acgatataca
    20161 ggggacgact gaggatttca tagaagccgt ttctagcgct ttgtttggct actcttatat
    20221 cttatacccg actatcaaac aaggcttata tttagagctt gcagctttag aaagtggtat
    20281 tatcaaaaag caagaactaa gcaataccag agtacaaaca agcagggtaa atacgaccga
    20341 gaataacctt ataaatgttc taaaactaaa agagtacact ttacagagaa ttgagcgact
    20401 tactgaagag agaatggaaa tatctaggct aatcgataag ctagccaatc cgcttgaacg
    20461 ttctgttctc aggctgttct acttgaatgt tcttgacgct tggcaagttg ctgaggaaat
    20521 agataaatca aagactgcag tatacattat aaggcaaaaa gctatagaac acttagcaaa
    20581 tgtggggtaa taggtgagca caaaaaaacg cctagaacaa tctaagcgct aaagagtagt
    20641 ggacggtgtg cctgtcccgt catctcatac tatgaagttg cgtagcgaca ctatcatctc
    20701 tacctcactt ctctttagac taattatacc acaaaggagc gaactaatgg agctggataa
    20761 gtttaaaacg atgatgaacg tcagagaacg gatgacctac tttctacgtt tccagaggat
    20821 ggcagggagt gaaaaccaag ttacaataga cgaagaggct tggaaacttg tcttacctga
    20881 tcagtggaat ttgactagta agcatgaaaa agcaatccgt gaggggttgg aaatattcgc
    20941 ccaagacatc aacagtatag agaacaaacg agctagaaaa tactttatta tccattattg
    21001 ttacatgaga aagaaaacaa tgagcgaatg cgtagaaatg gcagctacta gctccactag
    21061 ctaccaccga tataaacaaa tagccgtctt aaattttgcg agaatccacc agaacggaga
    21121 gctagaagtg tataagtagg catttgtggt gttttgttga gaaatgttga gatttaagtg
    21181 aagggggatg acatgattga agattttttg attgatttgg ataatatcca attagaggat
    21241 atggagatag attttaacat ggatatagac atcgatttaa acatagattt tgaccttgat
    21301 ggtttagatt tgaccttact acaagaatta gaagcgtaaa tgttggtaaa tgtaggctga
    21361 ggcttcatat tcgcctccct atttcgcttg gtttcgtccc ggacgattaa aacaccatgg
    21421 ataaactaga agcccttaga aacgaatcag ggggactttt gtgaggtcat aatcttataa
    21481 accacgcgct tcatggtata atatacctat cagcaaccag caataaaaaa agcacgtttg
    21541 accgtgctag tttcttgcct gctgaactcg tcatttattg cccttttgtg gggctttttt
    21601 tgtggacttt ttgagaattt ttaagaactt ttaatgattt ctaatcaaat gagatttttc
    21661 aaaaagtcag taatatcaaa ggtttaggcg ctataaacaa gtttaaaagc gtgtagatta
    21721 caatctaaca caaaaaggga taaagtgcta accctctaat taagggttct cagtcaataa
    21781 ttttattcat ttttcgatca aaatcatatc gccccatcat gacaacatgc tcacaattac
    21841 tgcattttat tttgatatct gctcctacac gtgtaatttc ccaacgatta gcctttttac
    21901 cagtcgactt gattgtacaa gcgtgtggtt ttttcatctc aacaaaattt ccaacttgat
    21961 acatactact ctccttttct ttttcgatta tatcataaaa gaggcgagcc aggctcaacc
    22021 tctttcactt aatttgtacg aactggtgta atgagctgca tgaagtcttc gtcagtatct
    22081 gctggcacaa gagtaaatgg acgaacagct gagataaagc taatggtcac cttttcgcta
    22141 tttaaagctt taagagaatc aatcaagtaa gttgggttga aactaatggt caaatcttca
    22201 ccagtaacct gatcagtatc gatttcttcg tttactttac caacttctgg agagtgaaca
    22261 tgggcgctaa caaccccatc cttaatttca agtttcacag taccattttg agtcgcactt
    22321 gataaaagac gggcacgctc cattgactgg cgtaagttta ccacattaaa agtaatagta
    22381 gtgttaaagt ctgttggaat caagcgatct gtatcaggat agtttccttc taggagacga
    22441 gtatagaagc taatattttc gcttctaaag aggatttggt tattggcaaa gaaaatttct
    22501 acagtttcga tatcatctgt aaataccgct gaaaattcgc gtagagaacg gctaggaatt
    22561 acgacatcaa aatcatcact atttttttca agagtcaatt ttttctggct taggcgatga
    22621 gagtctgttg caactgtttt taactctttg tgttgactca atacgaagtg gacacctgtt
    22681 aaaatcggac gactctcttg tgtacttgca gcaaaggctg tttcattaat aattttcttg
    22741 agtaattttg tttcaagtat taaaggagtg cttgctgaaa tttcttggat tcgtggatat
    22801 tgttcgctat cttttccttt tagggtaatt tctgatttgc cactggttaa aacaatttga
    22861 ttttgttcaa tttctttaaa atcaagagtc acatcaggta aactagatac tacattgata
    22921 aagaaagaag cttcaagaag gatcgaacct aaagaagtaa ttaacaaacc agcatcttca
    22981 tttttttgag aaataaaatt ttcaattgaa atttgaccat ttgaaccaat taaagtaata
    23041 ccttcattgg tcacgtcaat ttttactgtt gataaaatag gaatggcatt tttagaacta
    23101 atagctctct tagtagtatt taatgcttgt agaaataaat ttttattaat tgaaaaatgc
    23161 atcatggatt ctcctttatt tatttttagt attagaaaga taatagtaat aatagagtct
    23221 gtgaaatctg tggaaaacag cctttaaaca agtcatatca agttttttag cttgtttaaa
    23281 aaatgtggat aaaaaagata aaaaagtaaa agttatccac aaattatttg attttctttt
    23341 tgattgattc aatttctaaa cgtaaattat cgtcttgatc aatcaaagat tttattttgg
    23401 catgggcatg aatgactgtg gtatgatctt ttcccccaaa ttccttccca atttttggaa
    23461 gactattatc tgttagttct ctagataaat acatggctac ttgacgggcc aaaacaatat
    23521 tttgaaggcg tctacttccc ttcatttctt tgatactaac accataaaag ttaccaactt
    23581 cagtttggat tttatcaatt gggatgacga gcatttggct aacatcttgt ttgcgggctc
    23641 taatggcttc tgcagcaata tcaatagtga tatccttgat tttttttact ctggcaatta
    23701 aagtgatgtc gttgatggct ccctcaagat ctcgaacatt tgaatcaaat tgcccagcta
    23761 ggtattctag agtatcactt tggaaattgt agcctaaatg ttccgtttta ctttgtaaaa
    23821 tggcaatacg tgtttcaaag tcagggggtg tgatagtttg tgtcaatccc caactaaaac
    23881 gcgtgacaag cctctcctcg agcccttcta gatgttttgg actacgatca ctcgttagga
    23941 caatctgttt ttgcttgtca tgaagggcgt taaaggtatt gaaaaattct tcctgagttg
    24001 cgactttttt tccgctgagt gactggatat catcgattaa caaaagatca agactacgat
    24061 aggtcttttt aaacttttcc atttccccaa gtcttaggtg atcaagaaag tcattaataa
    24121 agctttcggc aggaatatat ttaacacgcg cattaggaat attttttaga atttcatttc
    24181 caatagcgtt taataagtga gtcttaccaa ggcctggtcc tccatagata aaaagagggt
    24241 tataggtcag agctaaatct tcagagacag ctaaagcggc tgatacagcc caaacatttc
    24301 catccccttg aataaagtta tcaaaggtat atttttcttt taatcccgta tctgaataag
    24361 gaatagatac taactttgga ctatagttat aaagagttaa atttgtagct tcttcaactt
    24421 gtgagctagt cgtatcttga ggtttggtga aaatatagtg gggagttatt tcagcgtcat
    24481 aaatttcaaa accagctact acaataatat cttttagttg tttttcccag accatttcca
    24541 tttcagagcg aggtagaaat atagtggcaa cattttcctc taccttgatg agttcagctt
    24601 gaatagcata gaaatcatac atggatcgag tcagtctttc ttgtgcaaat tctaatatac
    24661 gattccaaaa ttgtttttct ttcaatcctt tctcctcctt tactatttaa aagtttaata
    24721 ctagagatat tttaccatag atagcaagaa ttttccacaa gttgtgaaaa ataatccaca
    24781 atgttaccaa actttatcca caggttgggg ataaaagaag aaattattga tttattaagc
    24841 tttttatcga aaaacatagt ggataacctt gtgagataaa aaaataaaag aacagcctta
    24901 tttcaggctg ttgataattc tactatattc ttcttgattt gaaaaagaaa taatgatttt
    24961 tccactgtct tttttagata gtttaatttc tacatctaat ccgagtagtt ttcttaactg
    25021 tttttcttca ttgtgtatga aatgattagt tttttgctgt ttcttttgtt ttttctctgt
    25081 cagaagagct tctaacttcc ttacagaaat atcttcttct ataatccgtt gaaagaaata
    25141 gtcttgttgt tccttattta atccaactag ggaacgcgca tgggcttgtg atagtttgcc
    25201 attttctact tctgagagaa tttgttctgg caaggaaagt aaacgaatgg agttgctgat
    25261 atatggacga gacttgccca ttttatctgc aatttcagca tgggtgaatc ctttctctac
    25321 gagagattca taggcgcgtg cttcttctat tgggtttaaa ttttctctct gtaaattttc
    25381 aataatggac tggaccatca tctcttggtc tgaaatctgt ttaacaacag ctgggataga
    25441 ccgtagacca gctaaaagtg aagcccgata gcgtctctct cctgcaagga tttcataacc
    25501 aataacagga gattgacgaa caataatcgg ttgaatgacc ccattttctt tgatagattg
    25561 tgctagttca tctagttttt ctctatcaaa ttcttttcgg ggttgatagg gatttttttg
    25621 tatatctgtg atagaaatca tttcaaattt ttccatgatt ctacactaac acatcttttc
    25681 tcttatgtaa agctttcttt acatagatgt caattaagat tctaaatcac ctgaactctt
    25741 gtcaagtttg atagaggtag tttcttcttt cccgttacga tagtaggtta tcttaatggt
    25801 gtctccgata gaatggttgt aaagagcact ttgtaagtct gttgatgaag caatctcttt
    25861 gtcatctact tttgtaatca catcgtattt ttcaaggtga ccattggcag gcatattact
    25921 ttgtaccgaa cgaacaacta caccagatgt aacattactt ggaatattga gtcttctgat
    25981 gtcgcttgta ctcacattag ataaattaac catctggatt cccaaagctg gacgcgtcac
    26041 ttttccgttt ttttctaact gttcaataat attgatagca tcatttgcag gaattgcgaa
    26101 accaagacct tctacagatg ttcctccatt tgtagcaatt ttacttgagg taattccgat
    26161 aacctgccct tgaatattga tcagtgggcc gccagagtta cctgggttaa tagcagtatc
    26221 agtttggatg gcttttgtag aaatagcttg tccatcttcc gattttaagg atacatttct
    26281 attgagactg gatacgatac cttgagtgac agtatttgca tattcagaac ctaacgggct
    26341 accgatggca atagcaattt ctcctacagt taacttacta gaatcaccaa actcagctac
    26401 tgttgtcact ttttctgaag agattttgac gacagcaata tcagagaaag tgtcagctcc
    26461 gacaatttct ccaggtactt tagtcccatc tgacaatcga atatctactt tgctggcgcc
    26521 atttataacg tgattgttgg tgacgatgta agcttcttta tcattctttt tataaataac
    26581 tccagatcct tcactagaga ttcgctgaga atctgtgtca gtatcatcat tgccaaatac
    26641 gctattttgt ctgtttgccg aataagtaat aacagaaaca acagcatctt ttactttgtt
    26701 aacagcctgt gttgttgaat tttcgttctt ataggcagtt tgtgtaatag tactattgtt
    26761 gttagagttg tttacactac ttttttgagt tagttgagtt attgaaaaac tacccaaggc
    26821 tccactaaaa aagctaatga cgataacgac taataattga aaccattttt tgtaaaatgt
    26881 ttttagatgt ttcatatttg cctccatatg tttgaattac tgaaagtata aactgactag
    26941 cttaattata acttaaacac aaaagtttta cacaaactgt ggataactct tttgaaactg
    27001 tgattttctt aattgaaatc tattttttat tttgtgaata agatgtgaaa aaatagagaa
    27061 tatgttagaa tagagtcatg aaaattaaag ttgtaacagt tgggaaactg aaagaaaagt
    27121 atttaaaaga tggtatcgca gagtattcaa aacgaatttc tagatttgct aagtttgaaa
    27181 tgattgagtt atcagatgaa aaaacaccag ataaggccag tgaatcagaa aatcaaaaga
    27241 ttttagaaat agaaggtcag agaattttat caaaaattgc tgaccgtgat ttcgttattg
    27301 tgttagccat tgaagggaaa actttcttct cagaagaatt tagtaagcag ttagaagaaa
    27361 cttctataaa aggattttct acttttactt ttattattgg gggaagttta ggattgtcat
    27421 catctgtaaa aaatagagcc aatctttctg tcagttttgg tcgcctaacc ttgcctcatc
    27481 agttaatgag actagttctt gttgaacaaa tctatcgcgc ttttacgatt cagcagggat
    27541 tcccctacca taaatagaaa attgactttt aattgaattt ttggtagaat aattgtgtta
    27601 ggtctcatag ctcagctgga tagagcattc gccttctaag cgaacggtcg caggttcgaa
    27661 tcctgctggg atcaatataa tagcaaagct gggaattttc ccggcttttt tcttaaaaaa
    27721 gtacactttg ggagaaaaaa atgacagttg agagaatttt atctaaagcg aaattccatt
    27781 ttgtataatg gtttttgtaa gttagcttac aagaaaaaac attttaggag attttattat
    27841 gaaaaacaca gttaaattgg aacagtttgt agctttgaag gaaaaagact tacaaaagat
    27901 taaaggtggg gagatgagga tttcaagaat catccttgat tttcttttcc tacgaaaaaa
    27961 gtaatgaaat aaggagaaag agtaatggat ttacttggat ttgggacagt tattgttcat
    28021 tttttaatta ttagtcacag ttaccgttta atttgtaaag gtcgaataaa tagaaaagaa
    28081 ttatacgttt ttggtgctta tacattacta actgaaatag tacttgaatt ttccttttat
    28141 cttctatatt tagataaaat agggattgaa agatttttat ttcctttggg cttatattcc
    28201 tattttcgat ggatgaaaca gtatgagagg gatagaggac tattcctaag tttactacta
    28261 tctcttttat atgagagcac tcataacttt ctgtccgtaa ctttctcctc tataacagga
    28321 gataattttg ttttacaata tcatttccca ttctttttcg ttgtgacggt gttaacctat
    28381 tttgttacat taaaaatcat ttattatttc catttggaac tagcctattt tgacaaggac
    28441 tacctttatc ctttcttgaa aaaagtattt tttgctttac tattgctaca tattgtatct
    28501 ttcgtttcag atatggtaag tacgattaaa catttgaata gttttggaag tattttgtca
    28561 tctattgtct ttatctctct ccttttgacc ttctttgcaa tgaattctca taaagttcaa
    28621 atggagaaag agattgcttt gaagcagaag aaatttgaac agaaacattt acagaattac
    28681 acagatgaaa ttgttggtct gtataatgaa atccgtggtt ttagacatga ttatgctgga
    28741 atgcttgtca gcatgcagat ggcaattgac agtggtaatt tacaggaaat tgacagaatt
    28801 tacaatgaag ttttagtcaa agcaaatcat aaattgcgtt cagataagta cacttacttt
    28861 gatttgaaca acatagaaga ctcagcttta cgaagtttgg ttgctcagtc aattgtctat
    28921 gctcgaaata atggtgtaga gtttacactg gaagtaaaag atacgattac caagcttcca
    28981 attgaactat tggatttggt tcgtatcatg agcgttttat tgaataatgc tgtcgaagga
    29041 tcggctgata gctataaaaa gcagatggaa gtagcagtta ttaagatgga aactgaaaca
    29101 gttattgtga ttcagaattc atgtaaaatg acgatgactc cttcaggaga tctatttgcc
    29161 ttaggattct ccactaaggg aagaaatcgc ggagtcggat taaataatgt gaaagaacta
    29221 ctagataagt acaacaatat tattttagaa acagagatgg aaggcagtac atttagacaa
    29281 atcattagat ttaagaggga atttgaatga aagttttaat tttagaagat gttattgaac
    29341 atcaagtgag actagagaga atattggatg aaatttcgaa agaatcgaat attccaatat
    29401 catacaagac aacgggaaaa gtccgtgaat ttgaagaata cattgaaaat gatgaagtaa
    29461 atcagcttta tttcctagat atcgatattc atggaattga gaaaaaggga tttgaagtgg
    29521 ctcagctcat tcgtcattac aatccttacg ctattatcgt ctttatcact agtcgatcag
    29581 agtttgcgac tctaacctat aaataccagg tatcagccct agattttgtt gataaggata
    29641 tcaatgatga gatgtttaag aagagaattg agcaaaatat cttctacacg aagagtatgt
    29701 tacttgaaaa tgaagatgtt gtagattatt tcgactacaa ttacaaggga aatgatttaa
    29761 aaattcctta ccatgatatt ttgtatattg aaacaacagg ggtatctcat aaattgcgca
    29821 ttattggtaa gaattttgca aaagagtttt atggtaccat gacagatatt caggaaaagg
    29881 acaaacatac tcagcgattt tattctcctc acaagtcatt tttggtaaat ataggcaata
    29941 tcagagaaat tgatcgaaaa aacttagaaa ttgttttcta tgaagaccat cgttgtccta
    30001 tttcaagatt aaaaattaga aaattaaaag atattttaga gaaaaaatct caaaagtgat
    30061 tgacaattag caagaaattg atataatggt tatatctgct acagatagaa ggtccgttgg
    30121 tcaaggggtt aagacaccgc cttttcacgg cggtaacacg ggttcgaatc ccgtacggac
    30181 tattttatcc gccatagctc agttggtagt agcgcatgac tgttaatcat gatgtcgtag
    30241 gttcgagtcc tactggcgga gtatagataa aagggaacac agctgtgttc ctctttttgt
    30301 atcaatttgt atcaccaagc attttcataa ggaagtctgt tatttcttga gaactttctt
    30361 tttttccatg tgcaatccaa gtttggcaga caccaaaaag tgcatgagtt agatagatgc
    30421 tactatattc taattcagtg gtatttagat tcagttgcat aaatcgcttt tgtaaatcta
    30481 tactgagcat gatatgaagt ttatttcgta agaaattttg gatttcttta gtcccatttt
    30541 cagaaagaag ggcagccaga agtggttctg actctagata ttcaaagact tctaaaatag
    30601 cgtctctttt gtgatgagca tgtttttgaa aaatatattc aaatgtatgg aatagcttgc
    30661 tttgatagta ctcaatcata tcatacttat ccttatagtg agtatagaag ctggaacgac
    30721 taattctggc tttttctact aatttgacag tagaaatttt atcaaatggc tgttccatca
    30781 gtaattgtac catagcattt tcaatagttc gctttgtttt taagcgtttg ttactttctt
    30841 gcatatttcc tccttgtaaa caaattagac tatatgtcta aaaatagatt ttttaatgta
    30901 taatccatta tatcaaaatt ttagacaata tgtttaaaaa aaggagaaac tatgtttaaa
    30961 gaatggaaag caatttttaa aaaaccaacc tttattattg tcataatcgg gatttctctt
    31021 attccagctc tgtacaatat catatttttg tcatcaatgt gggacccata tgggcaattg
    31081 tctgacttac ctgtggcagt tgtaaataat gataaagagg cttcctataa tggtaatact
    31141 atggcaatag gaaaagacat ggtgtccaat ttaaaagaaa ataaaacctt ggattttcat
    31201 tttgtagatg aagaggaagg aaagaaggga ttggaagatg gcgattacta tatggtagtg
    31261 actttaccaa gtgatttatc tgaaaaaaca actacattat ccaatattca atcgacagca
    31321 gcttatcaat cattgacaag tgagcaacaa actgagataa gtgattctgt atctcaaaat
    31381 tttcaatcgg ctcagtcaat tgtagcttta gtacaaggtt tgcagggaag tttagaaaac
    31441 ttacaaaatc aatcttctaa tctttcgact ttaaaaaatc aagctaatca agtattacct
    31501 attacttcta cttctttgat aggattgtca agtggattaa cagagataca aggagctgtt
    31561 actagcaaat tagttcctgc cagtcagtcg attgcatcag gtgtaaacgc atatactaca
    31621 ggtgttgata aagtttctca gggcgcaagt caactaagtg aaaaaaatgc caccttgata
    31681 caaaaatctt ctagattgac agcaggagtt ggttaattac aatcaggatc tgggcaatta
    31741 gcagacaaat ccagtcagtt actttcaggt gcttctccat tagagaatag agctaataaa
    31801 ttggcagatg gatctgggaa actagcagaa ggtggaacaa agttaacttc tggattggaa
    31861 gatttacaga caggacttgc ttctttagga caaggactag gtaatgctag tgatcaactc
    31921 aaatcagtat caacagaatc taaaaatgca gagattttgt caaatccact caatctttca
    31981 aaaacagaca atgatcaagt tcctgtaaat ggaatcgcaa tagctcctta tatgatatca
    32041 gttgctcttt ttgttgcagc aatatcaaca aatatgatat tttcgaaatt gccttcagga
    32101 cgtcatccag agatccgttg ggcttggttg aaatctcgat ctgaaataaa tggtattata
    32161 gctgttttgg caggaatttt ggtatatgga ggagttcatc ttattggttt aactgctaat
    32221 catgagatga gaatatttat tctcatcatc ctaacaagtt tagtattcat gtctatggtg
    32281 accactttaa caacgtggaa tagccgtata ggagctttct tctcacttat tttgctttta
    32341 ctacagttag catcaagtgc aggtacttat ccacttgctt tgacaaatga tttctttaga
    32401 tctattaatc cctggttacc aatgagctat tcagtttcgg gattacgaca aacaatctcc
    32461 atcaacaagt cattttccta gctgtcatac tagctctatt tactggttta ggtatactag
    32521 cctatcaaca taagaaaatg gaagaagatt aaaaaaatcg accgatt
//
LOCUS       DAVDZK010000024        32272 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVDZK010000024 DAVDZK010000000
VERSION     DAVDZK010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.025"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(<1..314)
                     /locus_tag="VUX16_001318"
     CDS             complement(<1..314)
                     /locus_tag="VUX16_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET8124275.1"
                     /translation="MSNIYDSANELSRGLRELPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQDKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VF"
     gene            complement(325..1428)
                     /locus_tag="VUX16_001319"
     CDS             complement(325..1428)
                     /locus_tag="VUX16_001319"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET8124276.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADIIILSLPIKQTISFIKELANLDLKEGVIISDAGSTKSA
                     IVDAAENYLAGKPVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSPDTLEE
                     MKELLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNRETILERIEDFKERLDEVGQAISKGDEEQIWNFFN
                     QAREQRQAMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVVK"
     gene            complement(1438..2604)
                     /gene="aroC"
                     /locus_tag="VUX16_001320"
     CDS             complement(1438..2604)
                     /gene="aroC"
                     /locus_tag="VUX16_001320"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET8124277.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQERGQEIKDYIDKIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(2614..3681)
                     /locus_tag="VUX16_001321"
     CDS             complement(2614..3681)
                     /locus_tag="VUX16_001321"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET8124278.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(3700..4554)
                     /locus_tag="VUX16_001322"
     CDS             complement(3700..4554)
                     /locus_tag="VUX16_001322"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET8124279.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGTYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(4544..5221)
                     /locus_tag="VUX16_001323"
     CDS             complement(4544..5221)
                     /locus_tag="VUX16_001323"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET8124280.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLGFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAAMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTMSMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(5218..6381)
                     /locus_tag="VUX16_001324"
     CDS             complement(5218..6381)
                     /locus_tag="VUX16_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET8124281.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASELENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSTYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVVAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(7068..8702)
                     /locus_tag="VUX16_001325"
     CDS             complement(7068..8702)
                     /locus_tag="VUX16_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124282.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMIICFSNIAIHFPFEEMPVYFSFMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFVLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTIKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(8683..9432)
                     /locus_tag="VUX16_001326"
     CDS             complement(8683..9432)
                     /locus_tag="VUX16_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124283.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVADASQGH"
     gene            9611..11065
                     /locus_tag="VUX16_001327"
     CDS             9611..11065
                     /locus_tag="VUX16_001327"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET8124284.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFDASRAGSNYNLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEVLDRLLTIR
                     KDLAYGEQTDYFDDANCIGWVRSGAENQSPIAVLISNDQENSKSMFIGQEWAKQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSAASVSVWATNTI"
     gene            complement(11155..13773)
                     /gene="alaS"
                     /locus_tag="VUX16_001328"
     CDS             complement(11155..13773)
                     /gene="alaS"
                     /locus_tag="VUX16_001328"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET8124285.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGSSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETPFYAEMGGQVA
                     DHGQILNASGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLVIDTNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIVDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(13795..14280)
                     /locus_tag="VUX16_001329"
     CDS             complement(13795..14280)
                     /locus_tag="VUX16_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET8124286.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(14555..14794)
                     /locus_tag="VUX16_001330"
     CDS             complement(14555..14794)
                     /locus_tag="VUX16_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124287.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(15055..16125)
                     /locus_tag="VUX16_001331"
     CDS             complement(15055..16125)
                     /locus_tag="VUX16_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET8124288.1"
                     /translation="MKKLYSFLAGIVAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLEQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKLEGLENIGLEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNAAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDA
                     AYAFINFMLKPENALKNAEYVGYSTPNLPAKELLPEEKKEDKTFYPDAETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(16122..16895)
                     /locus_tag="VUX16_001332"
     CDS             complement(16122..16895)
                     /locus_tag="VUX16_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124289.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLIVTQTFFLAFLSAFIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTKLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(16892..17698)
                     /locus_tag="VUX16_001333"
     CDS             complement(16892..17698)
                     /locus_tag="VUX16_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124290.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGHRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(17679..18836)
                     /locus_tag="VUX16_001334"
     CDS             complement(17679..18836)
                     /locus_tag="VUX16_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124291.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDILLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILSGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(18996..19901)
                     /gene="murB"
                     /locus_tag="VUX16_001335"
     CDS             complement(18996..19901)
                     /gene="murB"
                     /locus_tag="VUX16_001335"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET8124292.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSSITLEREVRILGESK"
     gene            complement(20013..20765)
                     /locus_tag="VUX16_001336"
     CDS             complement(20013..20765)
                     /locus_tag="VUX16_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET8124293.1"
                     /translation="MTIHIIIIMLLLLVFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLVYIIYGLAMAAFFEETARLVFFKCLEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLSQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(20775..21506)
                     /gene="budA"
                     /locus_tag="VUX16_001337"
     CDS             complement(20775..21506)
                     /gene="budA"
                     /locus_tag="VUX16_001337"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET8124294.1"
                     /translation="MDKNVQEPAKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGTGEQPEIVEVSPDTLIPYAAVVPHQAEVIFRQRFEMTD
                     KELEERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     GGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            21648..22919
                     /locus_tag="VUX16_001338"
     CDS             21648..22919
                     /locus_tag="VUX16_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET8124295.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKTNQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(22939..23754)
                     /locus_tag="VUX16_001339"
     CDS             complement(22939..23754)
                     /locus_tag="VUX16_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET8124296.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     CLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(23911..24564)
                     /gene="phoU"
                     /locus_tag="VUX16_001340"
     CDS             complement(23911..24564)
                     /gene="phoU"
                     /locus_tag="VUX16_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET8124297.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(24576..25334)
                     /gene="pstB"
                     /locus_tag="VUX16_001341"
     CDS             complement(24576..25334)
                     /gene="pstB"
                     /locus_tag="VUX16_001341"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET8124298.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(25347..26150)
                     /gene="pstB"
                     /locus_tag="VUX16_001342"
     CDS             complement(25347..26150)
                     /gene="pstB"
                     /locus_tag="VUX16_001342"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET8124299.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(26161..27045)
                     /gene="pstA"
                     /locus_tag="VUX16_001343"
     CDS             complement(26161..27045)
                     /gene="pstA"
                     /locus_tag="VUX16_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET8124300.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(27035..27952)
                     /gene="pstC"
                     /locus_tag="VUX16_001344"
     CDS             complement(27035..27952)
                     /gene="pstC"
                     /locus_tag="VUX16_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET8124301.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(27952..28830)
                     /gene="pstS"
                     /locus_tag="VUX16_001345"
     CDS             complement(27952..28830)
                     /gene="pstS"
                     /locus_tag="VUX16_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET8124302.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTMLEGRQ"
     gene            complement(29404..30708)
                     /locus_tag="VUX16_001346"
     CDS             complement(29404..30708)
                     /locus_tag="VUX16_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET8124303.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(30709..31482)
                     /locus_tag="VUX16_001347"
     CDS             complement(30709..31482)
                     /locus_tag="VUX16_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET8124304.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(31472..31750)
                     /locus_tag="VUX16_001348"
     CDS             complement(31472..31750)
                     /locus_tag="VUX16_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET8124305.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKEEGKISLGK"
     gene            complement(31750..32151)
                     /locus_tag="VUX16_001349"
     CDS             complement(31750..32151)
                     /locus_tag="VUX16_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET8124306.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
BASE COUNT         9598 a         7464 c         6192 g         9018 t
ORIGIN      
        1 tcgaaaacaa ttttttcaat gtcagaaagg taaattgcca attgttgttg cttagtaaag
       61 aattctgaca agaggctatt tccttgaatc tgcttgccaa agccttccat cttatcttgg
      121 aaggacgcat ctggcatttg acctgtctgt gctagttttt gaatttcctc ttgaaaggca
      181 agataatctg taaagatttt gcttgcctca gcatctgctg caatcgcatc tttagctgct
      241 ttgacagcct tgtattctgg taattcgcgt agaccgcgac taagttcgtt tgcactatcg
      301 taaatatttg acatgatttt ctccttattt gacaacgact gtgtagtcgg tattttctgt
      361 tattagatgc tcagctcttt ccaagtcttg agcattttta aatgaaattt gtagaatccc
      421 gtgaatatcc tcacggtttt cctcgttgat atgaatattg accaaggaag ttccacgtag
      481 tagttccaaa atcctcaaga tgacatcttc ttcatcggga acgtcgacat agaggtcgta
      541 agaactatcc acacctccac gcttatggat ttccatggcc tgacgttgct cacgcgcttg
      601 gttgaaaaag ttccaaatct gctcttcatc tcccttgctg atagcctgac caacctcatc
      661 caaccgttcc ttgaaatcct caattcgctc cagaatggtc tcacgattag acaagagaat
      721 ggaagtccac atacctggct cactttccgc aattcgagtc atatctcgga aaccaccggc
      781 cgcaaagcgc cttgccatct catgttcttg agcatagacc gcggtctgtt ccatgagact
      841 agaagccaga atatgaggaa aatggctaat ctgagaagtg actcgatcat gctccttggc
      901 atcaatctcg ataaagcgag catgaagacc tgaaagcagc tccttcattt cctcaagcgt
      961 gtcaggactt gtcagactcg aaggcgtgaa gatataataa gcattttcaa aaagattgac
     1021 atctgccgaa gcagcccctg tcttgtgact accagccatg ggatgggctc ctacaaaacg
     1081 aacaggcttg ccagccaaat agttctccgc tgcatccaca atagctgact tggtcgaacc
     1141 agcatctgaa ataatgacac cttctttcaa gtccaagttg gccaactcct taataaagga
     1201 aatagtttgt ttaattggca agctgagaat aatgatatct gccaaaggag caaaactagc
     1261 aaaatcatcc gttgcacggt caatcatgcc ttctttcaag gcgatatctc tcgaagcttg
     1321 actacgatta taacctaaaa tttcataatc tggatgatcg cgtttgatac caagtgccat
     1381 agaggctcca atcaacccaa gacctgcgat atagattgtt tttgccatag gaactcctta
     1441 atagttcttt gtatagtctc ggtgtttggc taccgcttct tttagttcct caagattatc
     1501 tgatgagaat ttttcgagga tttcttgcgc cagaaccgtt gctacaactg cttccatgac
     1561 cattcctgca gctggaagag cagtcggatc acttctctcc acggttgcct tataaggttc
     1621 gtgggtttcg atatccacac tcataagagg tttataaaga gtaggaatgg gtttcatgac
     1681 cccacgaaca acgatgggtt gcccattagt cataccacct tcaaaaccac ctagattatt
     1741 ggtacggcga gtataaccgt cttctttaga ccagagaatt tcatccataa cttggctacc
     1801 tttacgataa ccagcctcaa agccaagacc aaattccacc cctttaaagg cattgatgga
     1861 gacaacagct tgagccaatc ttgcatccaa ttttctatcc cattggacat aggaaccaag
     1921 accaactgga acgcctccga cgactgtctc cacaacccca ccgatggtat caccatcacg
     1981 tttgattttg tcaatatagt ccttgatttc ctgtcctcgt tcttggttga caatagaaac
     2041 ttcagactgg gcagctcgtt gcttaatttc agcgactgtc agattttcag gaacatcgat
     2101 ttccttgcca ccaaagacca cgacatggtt ggcaatctcc atatccagct cagccaagag
     2161 gcgtttggct actgcaccaa ctgccacccg catggtggtt tcacgagctg atgaacgctc
     2221 caaagaattt cgcaaatcat caaaacggta cttaatcccc ccaaccaaat cggcatgacc
     2281 tgggcgagga tgagtaattt tccgcttgct tttaaggcgg tcttcaatgt cctccgcaga
     2341 catgatgtcc agccatttct ggtggtcctt attgatgaca tccatagtaa taggcgcccc
     2401 tgtcgtcttc ccgtggcgaa cgcccgaagt aaagacaacc tggtcactct caatcttcat
     2461 acgaccacca cgaccgtagc caccctgacg gcgtctaagg tcctcattga tatcctcagc
     2521 tgtcaatgga agtccagctg gaattccctc aataatagct gttagacggg ggccgtgtga
     2581 ttctcctgca gttaaatatc tcatacactc tccttatttt accaagtagt ctttcatctc
     2641 ttccagagaa actgggtgaa tggtcgctga accaagctct ggcaccaaga ccaatttcaa
     2701 ggtgttacca cgcgctttct tgtcatgagt aagagcctga taaagcttgt caacttccca
     2761 attttcatag tcaacaggca agccgaattt ctgacacatc tctgtgatag attgggtaat
     2821 gccagctggc atgaggcctt tttcctcagc aaccttggaa atctgtacca ttcccatggc
     2881 aacagcctct ccatgcatga ccttgccata accggcagtc gcttcgatgg catggccaat
     2941 agtgtggcca aaattgaggt aaagacgaat accattgtcc aactcatctt caaccaccat
     3001 cttgcgcttc acctgacaag aatgttcaat caaggtctct gcatgttcca aaatgctctc
     3061 aacagaacca ttcagccccg tcaagagagc ccacagttct ggatcctcaa tcaagccata
     3121 cttgataact tcacccatcc cttcaatcaa ctctcttttt ccgagggttt caagaacaag
     3181 tggatcaatc agaaccccat ctggttgggc aaaggtcccc accatatttt tagcaaatgg
     3241 tgtgttaacg cctgtctttc caccgataga agaatcaacc tgagctgtca aactagtcgg
     3301 aatctgaaca aagtgaatac cccgcatata ggtagaggct acaaagccag ccaggtcccc
     3361 aacaacgcca ccaccaagag ccacgattcc atcgctacga gtcagacctt gcttgactag
     3421 aaattcatag actttctgaa cagtagttaa attctttctt tcttcacctt ctaagaaatc
     3481 aaaaacagct acctgaaagc cagcatcttc taggctgagc ttgaccttct ctgcatagag
     3541 agaggctaca tggttatctg tcacaatgac taccttttgc ggttgccaga gttctcgcaa
     3601 ccactgacca gcctgggcca tacaaccttt ttcaatctga atatcataag gatgatgagg
     3661 aatatcgatt ctgattttca taggagagtc tccctttctt tattgatatt tttctgttaa
     3721 agactgccaa atctcttctg tcggcatttc cttgcctgtc cacagttgaa aagcttctgc
     3781 agcttgatag agcaacattc ccagaccatt gactgctgga ttgccctgac ttctagccca
     3841 tttcaaaaac ggtgtttcaa agggttggta tatgatatct gcaactaata gagtttctgg
     3901 taagactatg ttttcaggaa caggagagga ttggccatcc atgcccacac tggtggcatt
     3961 aactagcaaa tccgactcgg caatccttgc ttgcagttca gaaacatatt ctaaagcaca
     4021 caaatccact ttaaagcctg tctgctcctg taacttgtct aggtaaggtc ttgttttttc
     4081 catagaaacg gaacgaacaa agaccgaaat ctgactgacg ccatccaaaa tagcctgtgc
     4141 caagattgat ttagccgcac cacctgcacc cagcagggtc atctttttac ctgaaattgt
     4201 aaaagaaggc aagcacttaa aaaatccctt gccatctgta ttatatccaa ttaaattgcc
     4261 attctcattg acaaccgtat taaccgcacc aatcaagcgc gcttcatcgc tcagctcatc
     4321 caaataagga atcacctgct ccttataggg catggacaga ttgatgccaa acatctggta
     4381 gcgacgaata ttggccactg tttctgccaa gtcactcgct tcaatctccc aagccacgta
     4441 agtaccgttg gtagctgtcg cctcaaaggc tctattgtgg atgaagggag aaatagaatg
     4501 cttaatagga ttggcaacaa ctgcagctaa acgtgtatag ccatcaagct tcatccaaaa
     4561 tctccctgat ttttttcatg ctagctagag aaatctgccc aggggcacta acctcatcca
     4621 gactggcaaa agaccaactc gaaccagtca catccgcagt gatacgagag accttgccca
     4681 ccttacccat agacatggtc acatattcct gttcaggatt gagggtttta aagcctcgtg
     4741 tatagttcat caagtctaag acatcctgct ccgtgtgagc catcgccgca accttgacaa
     4801 gttttggatt taggatcgtc aactctgaca agatttccat catgttctca ggtgtttctt
     4861 ggaaattatg gtaactcaaa acaagatttg ggaagcccag catttcctca aaaacatcct
     4921 tgtagctata gtactcaaaa tcaatatagt ctggttgata gagttgcgca acttccttga
     4981 ttagatggat atactcttct ggagaaaggt cgatttctcc accttcggaa cgagttcgta
     5041 gcgtgaaaac caactcacgg cctgcgaatt tttcaaaaat ggctggagct acctgcaaaa
     5101 tcgcttcttt aggcagatag tcggcacgcc attcaatgat gtcggcatcc aggtacctcg
     5161 tggcatccag agcctgagcc tcctctaaac ttcttggcat tactgaaacg attaatttca
     5221 tttactaacc ttcatactaa tcaccttgag gtaattacta ctttcatctt ttttattata
     5281 ggcaaaatct gctggaagac catatttgtt taaaatctgg taacttcttc ctgcaaagcc
     5341 tttatcaatt tgttctgtaa atttctgacg ggaaacattg gcagcattgg tactggcaat
     5401 gataatccct cccggattta aaatctcaag actctgggaa atcaacttgt gataatcctt
     5461 ggccacagag aaagtttgtt ttttattccg agcaaagcta ggcggatcta ggacaatcac
     5521 atcgtaggtc aagtctttgc gtttggcata tttgaaatac tcaaagacat ccatgactat
     5581 aaaacgatgc tcgtctgtgc tgagcccatt tgcctgaaaa tgcgcttgag acaattctcg
     5641 tgaacgtttg gctagatcaa cagaagttgt ctggctagct cctcccatgg ccgcaactac
     5701 tgaaaaagcc gctgtgtagg aaaacatatt tagcaaggat ttacccatag ccaagccgtc
     5761 aactaaacta ccgcgaacct catgctggtc taggaaaatt cctgtcatca agccatcatt
     5821 cataaagact tgatacagga caccattttc taaaacagtg aaaaagtcag gtgcttcttg
     5881 accataaaca tgggcagatt catagtccaa ccccttaaag cggattttct cataagcccc
     5941 taaaacctca gggaaaacct gtctaaaggc ttctgatata gtctgacgaa tctgataaac
     6001 ataagagtta taccaagaaa aaacggcgta gtcgccataa aggtccactg tcagaccccc
     6061 aaagccatct ccctcttgat taaagagacg aaaggcagtt gtcaaatcat cttgatagta
     6121 ggtgcttctc ttttctttgg cttttctaaa caaggtttca aagaaagctt gattgaaggc
     6181 caccttgtct ttgctgacaa accagcccaa gcccttgttt tgctgagaaa gataggcagt
     6241 cccaagaaag tttccttcct gaccctgcac ctctacttcc tgatccttaa gattgacatt
     6301 ctcaagttca ctggcttcta gtaaaactag ccccttagca agcttctttt caaccctttt
     6361 gctgactctt attctattca taactaccat tatatcaaac ttttagacaa ttctcaaaaa
     6421 agaaactacc ctttcttttt tactcttctt ttaaaaaatg gtatactaga cttcctgcaa
     6481 aactaggaag taaatgtgta agaatcacaa taaaaaatgc tcttccgtct tggaggagct
     6541 tttcttttta tcaacgaaaa tcaaatggca aactatgaaa ctagcctcag gttaactgtg
     6601 agattatagg tagagaggtt gtatcagcaa tatgtgtctg tcaaatttag taacaaaggt
     6661 agtagaagaa agataaagaa ataaatcagc ttcagtagat atctggaaaa tttgatttta
     6721 tagagaagcc ttttgttaca aactcaatat actatcaata aataatatta tagaagcaac
     6781 aataattata atttcaccta tctgcataat tctatttcga actctaaata tatgttctat
     6841 caaaaatact tgaaaaagac acattatagg aattaaagtt tttgaaattg aaaaatattc
     6901 aaataaataa actataaaca acaaaaatag aactatgtta tatttcttat tcaaaacatt
     6961 cctccctata tatttttgat taccaatctt aatcatttac aactacattc taacaaacta
     7021 taaaagcgtt tgtcgaattg aatttatcaa gcaagcgacc aaccagctca tcttttttct
     7081 atttctgcca atatgcgtga caggtagtaa tgatagccaa aaatagcaag agcaagcaag
     7141 acgataagag ctcctactcc caagctgatg gcaaggatag gggagagaga ctgaaccaag
     7201 aatatgctcc caattacaag agccatcagg attgcactat aaataaacaa taaaactatg
     7261 gcgactatgc catttgaacg attcaccagg tccgtaatgc tactccaatt ggttgacaga
     7321 tttttaacgt ccttaaagta atggtggcaa gaaaggatga cactggcaat gatccagact
     7381 acaagaaggt aaatcatcga aaggatggac aagcctagat atagagaaag accgagtaaa
     7441 gtcagaattg gtaaaaagga ctgaacagca aagataatcc aaaatttcac tttcacataa
     7501 cgagcaaagt caaagggtaa actcttcaga aaatcaacat tttccctctc caaggacaag
     7561 gcaattgaat gcaggctggt gatattgtta ttgacaactg ctataaagag agctataaaa
     7621 aacaagggta accagtatgg aggatgaatg tctggaacta tctgagaatc tcggattttg
     7681 gaaatcagac tgatcatcat gagataagga aggaaagcac ttgtaaaaag cactgtaatc
     7741 acgccagtcc cctgtcccaa gagggtgagg tggtagcgta aaaccatacg gaaaaagccc
     7801 tttttaatag ttgaaatcct ctccttgctg cgacgttctt ttttgacctt ctcctcactg
     7861 ttaagcagga tcacgtcata aaaacgagga aggaccttct ttttggtcag ataaagcagg
     7921 aagagagtta gtcctatcca agcgagcaga cccactaagg cttctgtcga aaaaggctcc
     7981 actgctattt tgtaaaagat atgaagagga taaaggacaa atggaatgtc tctaactttg
     8041 tcaacaatac ttccaaaagt cgactgaaga aagaagataa atattaaagg tatgagaact
     8101 cctatcccaa tcatcacatt cgaaaaaata gactgatact ttctgaagac cctagtctga
     8161 gccaagaaat gtactgccac taccgtcact aaagtaacag agacaaataa taaggtcaag
     8221 gacagtagca tcaaaggcaa acccagccaa agagaaggag ctagactaat atagagggct
     8281 agaaaataag ctaggattgg tacaattcca gttagagctg gcaaaaggac agacagtcct
     8341 ttagcaatta taatctctga ttctttaaaa gcatagggac tataggaggc caaatcctta
     8401 ctctcataaa aaacattgta aaatgcagtt aaagaagttg aaaaggcaat cactagtaaa
     8461 atagcaacca tgaaactaaa ataaacaggc atttcctcaa aaggaaaatg aatggctata
     8521 ttactaaaac agatgatcat caagagactg gaaaaaatgt aagaacttaa gactctagcg
     8581 gaaacattta cttttttccc aggattctta gcctgcttct ttcgtagatt agccagatta
     8641 gcttcttgag atgaataaag gatattgata tcaactaatt ttttaatgac cttgagacgc
     8701 atccgcaacc tcctcttttc taccagcaag actaaggtag atactttcca aagactggtc
     8761 tgggtaatct tttctcaagt cctctacact accacaataa atcaaatgcc cctttttcaa
     8821 aatggcaatc cgatcacaga cttgctctgc cacctctagg acatgagttg aaaacaagac
     8881 tgtcttccct ttttgtgcat gttccttcat catctgtttc aaatcaaagg cagcctgggg
     8941 atccaaacca gtcaagggtt catccaagac ccaaatatcg ggatcagaca agagtgctcc
     9001 gatgacaaag actttctgac gcattccgtg agaaagagtt tcaataacct gatagcgatt
     9061 ttcagcaaaa tcaaaaacgt tcaatagcct agctagacta gcctccaagt cagatctact
     9121 cagatcatag gatgaggcga tcaattccca aaattcattg gccgttaagc gtaaaaataa
     9181 gtcaggcgag tctgctacgt agccaatctt tcgtttaata gccaagcgat tttccgataa
     9241 ctcctgaccg tctaccaaaa tacgaccact gctgggtgaa atgatactga ctagggattt
     9301 tatagtggtc gattttccag ccccattatg accaatcaag cccataatct ctccattttc
     9361 aatctgcaaa ttgagattac tcaaggcctc tttatcacca tacaacttac taacattttg
     9421 aaattcaatc atgggacaac tcctatcttt atctgtatta tacatcgcta tactagcact
     9481 ttgatacaaa aaaatcaata ctttatttta agtagttaaa atagtttcct tctatcttac
     9541 gcaaacgttt gctccgagag atactttatg atagaataaa gaacaagatt gacaagtaag
     9601 aggaaacatc atgcaaaatc aaacactcat gcaatacttt gaatggtatc tgccccacga
     9661 cggtcaacac tggacgcgtc tggctgaaaa tgctccacac ctagctcatc tggggatcag
     9721 tcacgtctgg atgccaccag ccttcaaggc aaccaacgaa aaagatgtcg gctatggggt
     9781 ctatgactta tttgacttag gagagttcaa ccaaaaaggg actgtccgca ccaagtatgg
     9841 tttcaaagaa gactatcttc aagccattca agcccttaaa gcacagggaa ttcaacccat
     9901 ggctgatgta gttctcaacc acaaggctgc tgccgataac agggaagcct ttcaggttat
     9961 cgaagttgat cctgtagacc gtacagttga acttggagaa cccttcacca tcaatggctg
    10021 gactagtttt accttcgatg gtcgccaaga tacctataat ggcttccact ggcattggta
    10081 ccacttcacc ggtacagact acgatgccaa acgcagtaaa tctgggattt atctgatcca
    10141 aggggacaac aagggctggg ctaacgagga attggtcgat aacgaaaacg gaaactacga
    10201 ctacctcatg tatgccgacc tagactttaa acatcctgaa gtcatccaaa acatctatga
    10261 ctgggctgat tggttcatgg aaacgactgg tgtagctggt ttccgtttgg atgccgttaa
    10321 gcatattgac tctttcttta tgcgcaactt catccgcgat atgaaggaaa aatacggtga
    10381 cgatttctat gtttttggtg aattttggaa cccagacaag gaagccaatc tggactatct
    10441 cgaaaaaacg gaagaacact ttgaccttgt cgatgttcgt ctccaccaga atctctttga
    10501 tgctagccga gcaggttcca actataacct tcgtggcatt ttcacagata gcctggttga
    10561 actcaaacct gacaaggctg ttacctttgt cgacaaccac gatacccaac gaggacaagc
    10621 tcttgaatct actgttgaag aatggttcaa accagcagcc tatgccctca ttctattacg
    10681 ccaagatggg cttccatgtg tcttttacgg cgactactat gggatttcag ggcaatatgc
    10741 tcaagaagat ttcaaagaag tccttgaccg cctcctaacc atccgaaaag atttggccta
    10801 tggagagcaa acagactact ttgatgatgc taactgtatc ggttgggtac gttcaggcgc
    10861 tgaaaatcaa tccccaatcg cagtcttgat ttcaaatgac caagaaaaca gcaagtcaat
    10921 gtttatcggc caagaatggg ctaaacaaac ctttgtagat ttacttggaa accaccaagg
    10981 tcaagttaca attgatgagg aaggttatgg acaattccca gtctcagctg cttcggtaag
    11041 tgtctgggca accaatacaa tctaatagct aatgataatc aagccaggtc caatcggatt
    11101 tggctttttt gcattcacaa aaagacctac ccaaatggat agatctttac tcgattacaa
    11161 tttacctgct actgcatcca acaattcttg aattttagct tggttgcttc ctcctgccat
    11221 ggccatgtct ggttttccac caccacgtcc atcgacgatt ggtgccaatt ctttgacaag
    11281 gtttcctgca tgaaggtctt ttgtcttgct tgctacaagg acattgactt tgtcaccgat
    11341 agcggcaact aggacaagaa gatcagagta gtctttttgt ttccaattat ctgcaaaagt
    11401 acgaagggca cctgcatctg atacagaaac ttggctagca atgtaacggt gaccgttgac
    11461 ttccttcaca tccttgaaga tatcgcctgc ggctgcagct gcggcttttt ctttcaattc
    11521 agcattttct ttttgaagtt gacgaagttg ttcttgaagt ccttctacct tgtgaggtac
    11581 ttccttgact tgaggtgctt tcaaggttgc tgcgacagct ttaagagcgt cttcttgttc
    11641 acggtaagct tcaaaggctt ccttaccagt cactgccaag atacggcgag ttcctgatcc
    11701 aatcccttct tctttgacaa tcttgaaaag accaatttca gaagtgttgc caacgtgggt
    11761 accaccacaa agctcgatag agtagtcacc gatagtaaca acacggactt ccttaccgta
    11821 tttctcacca aagagagcca tagctcccat ttctttagca gtgtcaatat ccgtttcaac
    11881 tgtcttcact tcaagagctt cccagatttt ctcgttgact tgctgttcaa tcgcacgcaa
    11941 ttcttcagca gttactgctt ggaaatgcgt aaagtcaaag cgaaggaatt caacttcgtt
    12001 aagagatcct gcttgtgttg cgtgatttcc aaggatattg tgaagggcag cgtgaagcaa
    12061 gtgagtcgca gtatggtttt tcatgacacg gtgacgacga tttgtatcaa ttaccaaggt
    12121 atattcttgg ttcaaggcaa gcggtgcaag gacttcaact gtatgaagag cttgtccgtt
    12181 tggagctttc tgaacattgg tcacagtagc cacgacctta cctgacgcat tcaagatttg
    12241 tccatggtca gctacctgtc cgcccatttc agcatagaat ggcgtttccg caaagataag
    12301 tgaggcagtt ccttctgata cagcttctac ttctgcattg tccgccacga tagctaccaa
    12361 tttagaagac aattggctag cattgtagtt gaagacactt tctacagtga tgttttgaag
    12421 agtttcattt tgcataccca ttgagctacc cttgacagct gacgcacgcg cgcgttcttg
    12481 ttgttctttc atggctgctt caaaaccttc acggtctaca gtcataccag cctcttcagc
    12541 aatttcttca gtcaattcaa ctgggaatcc gtatgtatca tagagtttaa agacatcttg
    12601 accagcaatg acagattgac ctttttcttt caagtctgcc acaatgcctt gggcaaagtg
    12661 ttgacctgag tgaagggtac gggcaaatga ttcttcttcg ctcttaacga ttttctcaat
    12721 aaagtcacgt ttctcaagca cttctgggta gtagctttcc atgatttttc caacagttgg
    12781 aaccaatttg taaaggaaag gctcgttgat acccaatttt tgaccatgca tagaagcacg
    12841 acggagaaga cgacgaagaa cataaccacg accttcattt cctggaaggg caccatcacc
    12901 gatagcaaat gaaagagaac gaatgtggtc tgcgataacc ttgaagctca tgttgtcgcc
    12961 atcttggtca taaaccttac cagacaattt ctcgacttca cggataatcg gcatgaagag
    13021 gtccgtttca aagttggtct tagccccttg gataacagcc accaaacgct ccaaaccagc
    13081 gcccgtatca atgttcttat gtggcaattc cttgtattcg ctacgaggaa cagcagggtc
    13141 tgcgttaaat tgtgacaaaa cgatgttcca gatttcaata taacggtcgt tttcaatatc
    13201 ttctgcaagc aggcgaagac cgatattttc tgggtcaaag gcttccccac ggtcaaagaa
    13261 gatttctgta tctggtccag aaggtcccgc accgatttcc cagaagttgt cctcaattgg
    13321 aatcaagtga cttggatcca ctcccacttc aatccagcgg ttgtaagaat ctttatcgtc
    13381 tggatagtag gtcatgtaaa gtttttcagc agggaaatca aaccattcag ggcttgtcaa
    13441 aagctcataa gcccaagtga tagcttcgtc acggaagtaa tccccgatag agaagttccc
    13501 cagcatttca aacatggtat ggtgacgcgc agtcttccct acgttttcga tgtcgttggt
    13561 acggatagcc ttttgggcat tggtaatacg tggattttca gggataatgg tcccgtcaaa
    13621 gtatttctta agggttgcta ccccagagtt gatccacaaa agagttgggt catttacagg
    13681 aaccaaactt actgatggtt ctactgagtg acctttggtc gcccagaaat caagccacat
    13741 ttggcgtact tgtgcactag atagttgttt catattgtct ccttattcac ttgtttaatg
    13801 tgattggctt tccagcattt ccacatagtc aatcgcgaca cagagggaaa tgactaggtc
    13861 tgcataagcg tcttcaagaa ccgttacggt ataggtagag gtcagatgga agagttcctt
    13921 cttaatttcc gcaatcaact gatcgcgatc atccagcaat ttgaaattca aatcccagat
    13981 attgccctcg atacgaagac ctagattatc aaactcatac ttatctcgcc agaaggtcaa
    14041 cttcttacga atgacaaaac tcgagccatc ccgaagctga atctcaaaac gaggaagcaa
    14101 ggtcaagatt tctttactaa tctcactgac ttgttcacca gccgcatcat agatggtaaa
    14161 ggttttagga atcttaaaaa atgatccctc cacctgatag gcaatttctc ccctgtcatc
    14221 cttgatagcg aagcgttcgc ctccaagacg aaacttttgt ttgacaagaa atgttttcat
    14281 caacacctcc aaaaatcaaa agacaagctc atatcacgaa gggcgaaaaa ccgcggtacc
    14341 accttcattc aatgaacttg tcattctctt gttcttatgc aattgtatga ttgagtagca
    14401 tgacttccta gcttagatgg ctcgcagcac cgccatttct ctggactaag acaagtgaaa
    14461 atcaattctc aactctctta ttataacgtt tttttaagct tgcgtcaact ggaaatgatc
    14521 tccgttgaat tagaccaatt ccctacatct ctgattactt tttcaggata tattttttct
    14581 tactgccatt tttcttttta tcccaaattt tcatattact aaacacagct actagaatat
    14641 ttccaaatat aaaggtgcct atcacccaat atatggactc agttgttagg tattgtcgat
    14701 ccaagccatc ctttaaatgg aatagtataa cagtttggtt aacaatcata aaggttggcc
    14761 agaaactttt tttgaaaaaa gtagacattt tcattatttg ttgccgcttt ctgtaaggtt
    14821 aatactcaat aaaaatcaaa aagcaaacta ggaagctagc ctcaagctgt acttgagtac
    14881 ggcaaggcaa cgctgacatg gtttgaagag tataggctta gtatactact aggcaagcaa
    14941 ataagcaaat aagcaaataa acaactagaa tagaaaaaga tagggctcta aaaactgact
    15001 tctattcctt aaaaacgaac cagcttgact gattcgtctt cttacgttta tctcctactt
    15061 ccgatacatt ttaaactgta ggaagaggtc gctatatttt cctgtccatt tatggtcaaa
    15121 tttctcataa acctctaggt gtttcatggt ttcagcatca ggatagaagg tcttgtcttc
    15181 ttttttctcc tctgggagta attccttagc tggtaggttt ggtgttgaat agccgacata
    15241 ctccgcattt ttgagagcat tttcgggttt caacataaag ttgataaagg cataggctgc
    15301 atcttggttt ttgactgttt tgggaatgac catattgtca aaccaaaggt tgctggcttc
    15361 tgtcggtacc acatagcgta gattttcatt tttttctagc atttggctag cttccccaga
    15421 gaaggtcaca ccgatggcag cattgttctg aatcatgtag cccttcatct cgtcggcaac
    15481 gatagccttg atatttggag tcaatttata gagcttatct actgtctctt ccaactgctg
    15541 tggatccttg gagttgaggc tgtaaccaag ggaattaagt cctagtccca gcacctcacg
    15601 cgccccatca aagagcataa tagagttctt atactctggc ttccagaggt catcccagtg
    15661 ctcaggcgct tcatctacca tagtttcatt gtagacaatt cccagggttc cccagaagta
    15721 agggatagag aatttatttc ctgggtcaaa ggactggttg aggaactcta atccgatatt
    15781 ttcaagacct tcaagttttg aatagtcaag cggtactaag aggtcttcgt ccttcatctt
    15841 gttaatcatg tattcactag gaatggcaat atcgtaggtc gttccaccct gcttgatctt
    15901 ggtatacatg gcttcgttgg agtcaaaggt ctcatactgg acttggatgc ctgtttcttc
    15961 tgtaaattgc tccaagagtt ctggatcgat atagtccccc cagttgtaga taaccagttt
    16021 ttgactatct cgactattga ttttactatc gagatgagtc gcaattcccc acaagacgag
    16081 gataatggct acaattcctg ctaaaaatga atagagtttt ttcatgcttg ctcctccttc
    16141 tcacgtgaga taaagtaata tccaacaact aggataatac taaagagaaa gacaagggca
    16201 gacagggcat tgatttctag cgaaatcccc ttacgagcac gagagtaaat ctcgactgac
    16261 agggttgaaa agccatttcc cgttacaaag aaggtcacag caaagtcatc tagcgaatag
    16321 gtgaaggcca tgaaataacc agcaatgata gatggagtca ggtaaggaag cataatttcc
    16381 ttgaacatct gaaattgact ggcaccaagg tcataggccg catgaatcat atcgccattc
    16441 atttccttga gacgaggcaa gaccatcaag accacgatag gaatggagaa ggccacgtga
    16501 ctagatagaa cggtcaaaaa gccaagtgaa aacttgagtt tggtaaagag gatcaagaaa
    16561 ctggcaccaa tcataacgtc aggcgcaacc atgaggatat tattgagtga aagaaaggct
    16621 tcttgatatt tcttacgaga ctggtagatg taaatagcac cgaaagtccc gataatggtc
    16681 gcaataaagg ctgataaaaa ggccaagaaa aaggtttgag tcacaattaa cataaggcga
    16741 ccatcgccaa acatggtttc aaagtgagtc cagctaaaac ctgtaaagct attcatatca
    16801 tcaccagcat taaaggcata gccaatcaaa taaaaaatcg gcaggtagag gacaagaaag
    16861 accagtccta gataaaggtt ggcaaatttt ttcatcgttc tctcctttcc ttggtcaccc
    16921 acatggtgat gaacatggtc aagatgagaa ttacaccgat ggttgaaccc ataccgtagt
    16981 tgtcattggt taggaaattc tgttcaatag ccgtccccaa ggtgataacg cggtgcccac
    17041 caatcaaacg ggtcagcatg aagagactca aacttgggat aaagacggat tgaaccccac
    17101 ttctcacacc gttcatcgat agagggaaga tgacatgacg gaaggtctcc cacttggtcg
    17161 caccgaggtc atagctggca ttgatgagat tgttatccat atcgtccaag acattgaaaa
    17221 tcggcaaaat cataaaggga agctcgatgt agcttgcgac aaagataaag gagaaatcgg
    17281 taaagagcaa ctgttgcgaa ccaattccga taaattccaa gaattgatta atagagccat
    17341 tctgaccaaa aatcccgata aaggcatagg ctttaaggag caaattgatc caggttggca
    17401 ggataatcag catgagccag agttgacggt gcttgagacg ggtcaaaaag agggctgtcg
    17461 gatagctgat aagcaaggtc acaaaggtta caatccctgc atagagtaca gagttgaaac
    17521 tcatttttag gtaggtcaag ttttgtgacg caaaataaga tttgtaattt tctaaactga
    17581 actggccttc gatgttgaaa aaggattgac cgaaaatcaa gaccaagggt gccagaacaa
    17641 agagggcaat ccaaagcatg tagggcacta caaagagttt agagcttgtt ttcttcatct
    17701 ctttcctcct cgattgcatt gatcaaacct gcttcttgct cttcgatttc cacgtattct
    17761 tcgatacgag catcgaactc ttcttctgtt tcgttgagac gcatgatatg gatgtcttct
    17821 ggttcaaagt ccagaccgat ttcctcacca acaatagcct tacgggttga gtggatcatc
    17881 cattcattcc caagctcgtc ataggcgata atttcatagt gaactccacg gaagagctgg
    17941 gtatccacct taacttggag cttgccttct tcaggaaggg taatgcgcaa gtcctctgga
    18001 cgaataacga cctcaacagg ttcatttggc ttcatccccc catcgactgc ttcgaagcgt
    18061 ttgccgttaa attcgaccaa gtagtcctca atcatggttc ctgacaagat atttgactcg
    18121 ccgataaagg tggcaacaaa gtgattgatt ggctcatcgt agatatctac tggtgttcca
    18181 gactgaacaa tctcgccatc attcataacg aaaatccagt cactcatggc cagcgcttct
    18241 tcctgatcat gagtaacaaa aacaaaggtg attcccaatc gttgttgcag ttcacgcagt
    18301 tcgtactgca tgtctgttcg taattttaag tccagcgctg acagaggttc gtccaacaac
    18361 accacacggg gttggttgat gatggcacgg gcaatagcca cacgctgacg ttgtcctcca
    18421 gaaagtttgc ggatggaacg tttttcatac ccttccaact gaaccatctt gagaacttcc
    18481 gctacgcgtt gctcgatttc tttcttgtca attttacgca agcgaagtgg aaaggcaaca
    18541 ttttcaaaca cattcatatg cggaaacaag gcataagatt ggaaaacggt atggacgtct
    18601 cgcttgttgg ttgggatgtc attgatacgg acaccatcca gcaaaatatc tcctgtcgtc
    18661 gcatccagta accctgcaat aatgtttagg atggttgatt tccccgaacc agatgcacct
    18721 agaagggtgt agaattttcc ttcttccaac tcaaagttga tgtctttgag aaccttggtg
    18781 ttgctgtctt caaaaacttt agagacgttt ttgaattcga taattggttt tttcaattgg
    18841 cataaattcc ttctttttca tagattaacc gatcggggct ctgtcaggtc cccactacct
    18901 cttgcaggga gtaaaaccac ctgcatacat cttcgctacc gataggcttt cacccccttt
    18961 ccatgacata gcagcagctt ttcaaataca gcttcctact tgctttcacc caagatccgg
    19021 acttctcttt caagcgtaat acttgagtgt tccttaactt tttcgataac cgattggatc
    19081 aagtcctcgt agtctttggc cgttccatct gcgacattga tcataaatcc tgcatgcttt
    19141 tctgacactt ctacgccacc gatacgatag cctttcaagc cagcttctga aattaactga
    19201 cctgcaaaat gcccgactgg acgcttaaag accgagccac aagatgggta ttccaaaggt
    19261 tgcttgagtt cacgtaggtg cgtcaagcgg tccatttcct gcttgataac ctgatgggtt
    19321 cctggggcta gggcaaattt aactgacaag acaactgcac cagactcctg aatagctgaa
    19381 tggcggtaac caaaagccaa gtctttagca gacagggttt cgatttctcc atccttggtc
    19441 aagaccttac aagactgcaa gatgtgagca atctcgccac cataggcacc cgcattcata
    19501 aagacagcac cgccaacgct tcctggaata ccacaagcaa actcaaagcc agtcaaacta
    19561 tgacggaggg caatgcgagt tgtttcaatc aagttagccc cagcttctgc ttcaatggta
    19621 tagccatcaa cagaaacgtt attgagcttg tcacacaaga tgacaaatcc acgaatccca
    19681 ccatcacgaa caatgatatt gcttgcatta ccaagaacca tccaagggat attttcttgg
    19741 ttggcaaatt tcacaacgcg agccaactca aaacgatttc gtggaaagac caaataatca
    19801 gcctctccac ctacttttgt ataactatag ctatgcaagg gttccttaaa acggatatca
    19861 attccttcta agatttcaag cattttttct cttacagaca tgtcactctt ccttttacaa
    19921 aattcattcc attataccat ttttagagac atttgacgac cataaaaata ccttgtttgg
    19981 attttgcata agaaaaagag gttcccccct ttttatgatt ttttacaaaa gatttccttg
    20041 gttccatagg cgaccagaac gagctccagt gctagaatca cttcaaccaa gactggattt
    20101 gtcaaccagc ctacttggga aagagatggt gccagatcaa agaaggcatg caagccatag
    20161 gctgctagga gataaatcca tttcttctgg cgaacagctt ggtaaaccca aactgtcaaa
    20221 agtaattgga aaccaagcgc caagattcgc tcaaaaccaa gcaaataaat ctgccagacc
    20281 gaaagtgact gaatggtttt taacatattt tcagacagta attgcataac ctgtggattc
    20341 tgagtttgaa ctgccgaaag aacaatgtaa agattgagta aactagtaag gcctagaaaa
    20401 atcaactcca agccaccatg cccaagtcca taggccaagg cgtctgcctt ttccaaactt
    20461 ctctttttct ccaagcattt gaagaaaaca agacgagccg tttcctcaaa aaatgctgcc
    20521 atggctaggc cataaataat atagacaagc ggatgatctt gcaagagggc aatactaccg
    20581 tctttttgag gatgcaaaat caagatatgc accagttttt ccaaaatctg cgaagagaca
    20641 aagaaagcga ctgcacccaa gcccaagaca gctagattaa tctggtattt ctttttggca
    20701 aaccaaatgc ttcctatcag aaaaactagc aacagcaaca tgataataat gatatgaatg
    20761 gtcattttct tctcctattc tgccttttca atatcttttt tcatctcgtc aacattgaac
    20821 ttagcaaaca agtattgacg gtcttggact gggaaacgtt ggtccaactg gtcaactgct
    20881 cccacctcga taatgccttc cttgatgaca aaatccatga catgtccacc gaaggtcaaa
    20941 tcatctgata tgaagtgcag atggtagcct gccacactga ccccatggaa aatctcaggc
    21001 gtccagaaac caacaatagt ccccccaaca ttgtcacgac tatattccgg ttgatgggtt
    21061 gcgacatcag caaacttggt atcgggtgtt gacttaggaa tcatacgcac atgcatatgt
    21121 gaaaattctc cccgaatctt gatagaacgg aaaagatttt ccccatcata ataagactca
    21181 attcgttctt ccaattcctt gtctgtcatc tcaaagcgct ggcggaaaat gacctctgcc
    21241 tgatgcggta ctactgctgc ataaggaata agggtatctg gtgacacttc cacaatttct
    21301 ggctgttctc ctgttccttt tgcctgataa gccttgccat ctaagacaat caattcccca
    21361 tcaatagaat ccaaggttcc caaaccaagg tcaccatgct ctagcaattc tcccactgtc
    21421 atggtaccac cataaaggcc agccatcaag gctccaagag tattgtattg aaataatttc
    21481 gctggttcct gcacgttctt atccattcac tttcttgtct gttattctat aaatgttact
    21541 cctaagtata ccacatttgc ccctagatgt gaacgagaga aacgctctag acattgccaa
    21601 gaaggaaaaa aaagggtaca atgtaacaaa atcaagggag gtctggaatg aagaaacaaa
    21661 gcaagtacaa agaggtcgtt tcctatctga aaaatggtat cgagtctgga cgatttccga
    21721 cgggtagtcg cctgccttct atccgtcaac tgagccttga ctttcactgc agcaaggaca
    21781 ccattcaacg agccctgctg gaattacggc acgaacaata cctctatgcc aagcctcaga
    21841 gtggctacta tgtattagaa caagggcaac atcaagacct agaaatcgag gttaccgacg
    21901 aacatgccag tgcctatgac gatttccgac tctgtgtcaa tgaaaccttg attggccgag
    21961 aaaactacct cttcaactac tatgacaatc aagaaggatt agaagaccta agacaatcca
    22021 ttcacaaact cctctttgac caagctctct actgcaagac taaccaacta gtactgactt
    22081 ctggaaccca gcaagccttg tttatcctat ctcaaatatc ctttcctagc caagccaagg
    22141 aaatcttggt ggaacagcca acctaccatc ggatgaatcg cctcttgatt gcacaggggc
    22201 tggactatca aacgattgaa cgaggcattg atgggattga cttggaggag ctggaaggcc
    22261 acttcaaaac aggaaaaatt aaatttttct acaccattcc ccgatttcac tatcctctgg
    22321 gacattccta ttctgagcaa gacaaacgat ctattcttaa cttagctgcc aagtatgatg
    22381 tctatatcgt agaggacgat tatctgggtg atttggactc caagaagggc caaaccttcc
    22441 actatcttga tacagaggag catgttattt atatcaagtc cttctcgacc agcctttttc
    22501 ctgcccttcg tattacagca ctcattcttc caaatgctat caaagaagca tttgtggcct
    22561 acaaaaatat cctagactac gacagcaacc tcattatgca aaaggccctg tcactctata
    22621 ttgacagtca attgtttgaa aaaaatcgtt tggctcgctt gaccaatcat gaatcttacc
    22681 aaaaacaaat cgaagaaagg ataactaaaa caccttgtcc cctccctcat tatcccctac
    22741 acgatggttt attgctagac ctgagacagt atcctaaaat cgccagtctc aaacacagtc
    22801 aactgggctt ggacttcttt gaagaggcct atttaagcac ctgtccttat caatttgcca
    22861 aggtgtccct agacaatctg gaaaatgttt taaactattt aaaagcagaa ttggaatgac
    22921 atccaactct gctttttctt attcttcaac ttcagttaga cttgctgctt tttcaagata
    22981 gctttggtaa gttccttcat ccttaagttt ttggataacc ttgtctacca cttctttcaa
    23041 atcatcacta ttttttctaa gagcaacggc attggcgtcg ccgtccttca tcttcaagca
    23101 gacagttgcg acagctaagc cagcgttttt agcagcataa ctaagtgcaa caggttcatc
    23161 catatgaaca gcatctactt ttccagcctg caattcattg actgcttcac ccatattagt
    23221 tagggaagtt aattgagctt ttggcaattg ttccttgacc attgattctg gaacagtccc
    23281 tttttgggct gcaatattag cactttctag gctagttaaa tccttgtatt tttccacatc
    23341 agccttacga accaagaaac taatcttgtt ttcatagtat gggattgaaa aatcaaagac
    23401 ttcttttctc tcgtcagtag cactaattcc tgcaactgct aggtcagcct taccagtttg
    23461 aagactggtc aaaacattgt caaaactcat gcttgagatt tccaacttaa ccccaagttc
    23521 atcagcgata gcctgagcca tgtcgatgtc tgcaccgact acctggttct ttccatcaac
    23581 caatgattga aattcaaagg gtgcatagtc aggactggtt gccacaacta atttcccctt
    23641 ttgcttaatg gcctcaacag ctgactgaga accattagaa cctgactggc aagctactaa
    23701 gaagaaactt gcaagaaaat tacataaaac aaatatccat ttttttgatt tcataaataa
    23761 acaacctctc tgttaatttt gtataattat aacgatatcc aagttacttg tcaagtgttt
    23821 tttaaatttt tatctcaaaa atattttttt gttcaaaaaa aggagccatc agttgattcc
    23881 aagctccttt ttatacagaa ttaaactatt ttatagttcg acaatcttac ctgtttcaaa
    23941 gtagacaacc cattcacaga tatttttagc atagtcaccg atacgctcca agtaggaaat
    24001 aacttggaaa taatcacgac ccgtaacaat ggcttctgga tttttcttaa tctcttcagt
    24061 cgcaaggtca cggatagttt caaaatagtg gttaatttgc tcatccatgg aggccacccg
    24121 gtatgcgtcg tcaacagaac cattaagata aagatcaagt gctgcttcaa caacgctttt
    24181 aacttcacgt cccatttttt taatttcttc ctctacagct gggatgcgtt cttccccctt
    24241 catacggatg gttgcctggg caatggctac agcgtgatcc cccatacgct ccacatctga
    24301 tacagcctta aggacagtca agactgtacg caaatcttga gagactggtt gttggagtgc
    24361 gatcatttca aatgatttct tttccagttt cacttcgtat tcatttactt ctgcatcatc
    24421 ttcgatgacc tcttttgcca ggtcacggtc atgcgtgaca aaagcacgta ccgtacgatt
    24481 gatttgtgag agcacttctt gtcccatagc gtagaactgg ttatgtaatt tctctaaatc
    24541 ttcttcaaat tgagatcgta acatctttca tctccttatc caaattttcc tgtaatatag
    24601 tcttccgttt ccttgtgttg gggatcaagg aacatctgct tggtatcatt aaattcaatc
    24661 aaatctccat ctaggaaaaa tcctgtctta tcagagatac gtgaagcttg ctgcatggaa
    24721 cgggttacca gaagcatggt gtacttgtct tttagaccat acaaggtttc ctcaatttta
    24781 ccagctgaaa tcggatccaa agccgaagtt ggctcatcca agaggatgat tttaggacta
    24841 gttgccaaga cacgggccac gcagacacgc tgctgttgac cacctgacaa tccaatagct
    24901 gaatcatata gacgatcctt gacctcatcc cagatagagg caccttgcaa ggctttttct
    24961 acggcttcat ccagaacctg cttatcctta attccattga tacgaagccc gtagacaaca
    25021 ttctcataga tagtcatagg gaaaggatta ggttgttgga aaaccattcc gatttcctta
    25081 cgtaattcaa ccgtatctgt acgcggactg tagatgttgt gaccattgta caccacggat
    25141 ccagttgtgg tcacctctgg attgagatct cccatgcggt taagagactt gaggagggtt
    25201 gacttccctg atccagatgg accaatcaag gctgtaattt ccttaggttg gaaagatagg
    25261 gaaacactat tcaaagcctt ctttttatta taataaacgg acaggtctga tacctgtaaa
    25321 atcgcatctg tcatacggtt tcctttctaa ccaaagtgac cagatacata gtcattggtg
    25381 gactgtagct tggcattttg gaaaatagtt gcagtcttgt catactcaat caaatcaccc
    25441 aagtaaaaga agcctgtata gtcacttgca cgagcagcct gctgcatatt atgcgttaca
    25501 atgatgatgg taaagttttt cttgagctca aacatggtct cttctagttg catggtcgca
    25561 atcggatcca aggctgaggc tggctcatcc attaagagga tatctggctt aacagagatg
    25621 gcacgagcga tacagagacg ttgttgctga ccacctgata aggtcaaggc tgacttgtgg
    25681 agatcgtctt taacctgatc ccagagggca gcctgacgaa gggaggtttc tacgatttca
    25741 tctaggactt gcttatcctt aactccagca cgttcatgcg caaaggtaat attacggtaa
    25801 attgacttag caaatggatt ggggcgttga aaaaccattc caatgtgttt acgcatttca
    25861 taaacgttga tttctggacg gttgacatca attccacgat agagaatctg cccagttact
    25921 ttagcaatat caatagtatc attcatgcga ttgagactgc gtaagtaggt agatttcccc
    25981 gatcccgacg gaccaatcaa agctgtaatt ttatttcttt caaattgcat atcaatcccc
    26041 ttaatggatt catttttacc atagtaaaca tggacatcct tagtagaaag ggctactttt
    26101 tcttcaggaa aggtaaggat atgcttctca tcccagttat atgttgacat ggcttctcct
    26161 ttaggcagcg gttaatttct tgtgtagata gcttccgaac ttacgagctc caaagttaaa
    26221 aatcaggata aagatcagga gcacagcggc agaacctgct gatacaattg ttccatctgg
    26281 aatagtgcct tcactattga ctttccagat atggacagcc aaggtttctg cttgacggaa
    26341 gatagagatg gggctagtca cactgaggat attccagtta gaccagtcaa gagctggcgc
    26401 cgattgccct gctgtataga tcagagctgc agcttcgcca aagatacgac cagatgccaa
    26461 gacgacaccc gttacaatac ctggaagcgc ttctggaata acaacatgaa ccactgtctc
    26521 ccagcgagaa atcccaagag ccagaccagc ctcacgttgg gtatggtgaa cgtgtttcaa
    26581 actatcctct acattacgcg tcatctgagg caagttaaag actgtcaagg ccaaggcacc
    26641 tgaaatgatt gaaaatccat actcaaactg gactacaaag atcaagtaac caaagagacc
    26701 caccaccact gatggtaaag aggacaagat ttcaatacaa gtccgcacaa agttggtaac
    26761 aggacctttt ttagcatatt cagccaagta aatcccagct cccatagaaa gaggtacaga
    26821 aataatcaag gtaatgacca ataggaaaaa ggaattgtaa agctgaatgc caatcccacc
    26881 acctgcttga aaagcagaag accttccagt caagaaagac caagagatat ggggcaagcc
    26941 ccgaaccaag atatagagaa tcaaggaagc caagattgtc acaatgatgc tagcaatcgt
    27001 atagaggaca gctgttgcaa gtttatctaa tttcttagcg cgcataattt ttctttcctc
    27061 tttctttcgt aatcaattta atcacactgt taaaaactaa actcatcaag agcagtacca
    27121 aggccagtga ccagagaaca ttattattta cagttcccat gacagtgttc ccaattccca
    27181 tagttaatat agaagttaaa gttgcagctg gtgtggtcaa ggaagttggg ataacagctg
    27241 agtttccgac aaccatctgg atagctagag cctcaccaaa ggcacgcgcc atcccaaaga
    27301 ccactgcagt gaaaatacca gaacgggccg ccttcaagat cacacgccag atagtctgcc
    27361 agcgagtagc tcccatagcg aaactggcct cacgataata acgaggaacc gcacgcaagc
    27421 tatccgttgt cataaaggtt acggtcggca aaatcatgac aaagaggacg gaaatccctg
    27481 acaaaatccc aaaaccagtc ccaccaaaga cactgcgaac aaagggaacg acgacttgca
    27541 agccaataaa tccgtacact actgaaggaa tcccaaccag gagttcaata gctggttgca
    27601 aaatcttcgc cccttttggt gatacttcgg tcataaaaac tgctgcacca atagcaaagg
    27661 gtgttgcgat aagggctgag agaatggtaa cgataaagga acccaaaatc ataggaaggg
    27721 caccaaattc tttactagaa ggattccaag ttcctcccaa aagaaagtca aagatattca
    27781 caccattgac aaagaaggtc gacaagcctt tttgcgctac gaaaaccaaa atcatggcca
    27841 caaggatgac tatcaaagaa agacaggcaa aggtcaaacc ttttcctaat ttctccagac
    27901 gagaattctt tgatggaagc aacattttct tagctaattc ttcttgattc attattgtct
    27961 cccttccaac attgtcacag ttccggcagc atctttttca accttcattt ccttaatcgg
    28021 aatatacttc aatcctttga caatcccttc ttgggtctca tccgagagaa caaaattgag
    28081 aaattctgca gccaactcat tgggctgccc caatgtatac atatgctcat aagaccacaa
    28141 gggccaatta ttgctactta tattttctgg acttaagtca tagccattca acttcatgct
    28201 tttgaccgaa tcatctatat aggtaagaga taaataagag atagctcctg gactttttga
    28261 tacgattgat tttaccgctc catttgaatc ctgctcctga ctttgcatgg cagactgacc
    28321 ttccataatg acagtatcaa aggtagcacg agagccagag ccggctgccc gattgataac
    28381 agagatgggt aagtccttac caccaacctc tttccaattg gttacctcac ctatgaagat
    28441 ttgacgaagt tgctctgtcg ttaggttatc aacatcaacc tccttattga caatcagagc
    28501 caagccagct accgcgacct tgtggtcaac aagagcagaa gcatcaattc cgtctttttc
    28561 ctcagcaaat acatctgagt ttcctatatc aactgcccca gactgaacct gggacaagcc
    28621 tgtaccagaa cctccccctt ggacattgac cgtttttcca acatggatcg tgccaaattc
    28681 atctgccgct acttcaacca agggttgcaa ggcagttgag ccaacagccg ttatggattc
    28741 tccacgatca atccagctag cacagcctac taaacaagcc gtcagccaaa aagcgataag
    28801 agacagagca agcttttttc tttttttcac tgtttttctc ctcgaaaata attatgaata
    28861 ctgtgaattt tttaagtagt tctttatgag ttgacgcatg aattcttacc aaatttctgc
    28921 gcaattgatt atttatataa tataggctat attactcttt cctaacctcc ttttttcata
    28981 tgtggataaa atctcttgtc tatcccttcc cccattgtca cccattatag tcatttcgtg
    29041 tctctttttc ccctttttaa tgcaagggaa attactctcc tcagatgata atccaaaagc
    29101 tagaaaggta tctcaaacct ctctactctc ccagactagt ttacaactaa aaggaaaaga
    29161 ttctatttta tgagaaatct agtttacaag cggtaagaac gctaataact aaacttcttg
    29221 tactctttga aaatctcttc aaaccagtgt tttgagctat ctatggctag cttcctagtt
    29281 tgctctttga ttttcatcga gtagtaaaac tacatgtgat ggcaatcaag atatcaagaa
    29341 tcatcctact aaaaaaatcc atactttcac tataacatag aataagatat ttgactagca
    29401 ttttcatttg aatctgaggc cttttggaaa ataatttttc aaaacatttc cagtaacctt
    29461 tgcaaagccc aagccattgc ctttaaccaa aacttggtac caaccatttg gcagactttc
    29521 tgccagctga acggtttctc cagccgcata cttgacaaac gcttcttggc caatttcaac
    29581 cgactgttcg acctgactcg gtttcaaggc taaaccaaga gcgaaactgg gctcaaagcg
    29641 tttcttctta aaagtgccca gatgcagtcc attgcgagca atcttgagct tccctaaatc
    29701 tggcaaaagt tctggcaaga gataaagctg gtctccaaaa gtctgcaaga tacccggtag
    29761 attgaccttc aaatggtttt gggcaaattc ctgccacaag gcaacttgtt cacggctgag
    29821 gttactctta cttgccttaa atttaggagc tggattgtta cccttaaact gtagatgggc
    29881 aacaaactga ccctctccct taaactgatg agggtacatc cgagccgttt ctggcaggtc
    29941 aataccagct accattccat tgatatgctc tactggcaac aagtcaaaat catactcttc
    30001 cagcaaccaa ttgacaatct cttcgttttc ctcgggtgcc caggtacagg tcgaataaac
    30061 cagacgacca ccttcagcta acatggtcac tgcatcctcc agaatttctc tttgcaagct
    30121 agcacattga ctcggataat ctaagctcca atagtccata gcatcaggct gcttacgaaa
    30181 cattccttca ccagagcaag gggcatcaag aacgattaag tcaaaatagc ctttaaagac
    30241 cttgaccaag cggtcggcag attcattggt caccacgaca tttgtcgctc caaaacgctc
    30301 catgttttca accaaaatct tagcccgttt gcttgaaatt tcattggaaa caagtagccc
    30361 ctcccctgct agataggctg ccagttgagt tgatttgccc cccggtgcag cagccaagtc
    30421 caagaccttc ataccaggac tgggttgggc tacttgagcc accatttgag cagcaggttc
    30481 ttgcgaataa actaaacctg tagcatgctc aggcgatttc cctgaaacct tcccatagtg
    30541 gccccaaggg gtttgagtaa tggcatcaga aaaggaaagt tgctcttctt ttaagggatt
    30601 gacccgaaag gccgaaaccg cttcctcctc aaaagaggca agaaaatctc ttgcctcatc
    30661 tcctagtatt tctttatatt tttcaacaaa tccttctgga aattgcattt aagttctttt
    30721 cctttcgtaa atataggact gaatttcctc ctgcatctca agaggcacca tcatgacagg
    30781 ctgtctggtt tgaaaatcag gagcttcacc aaaaagggtc acaacccgat agcccagact
    30841 ttcccctaaa atactagctg cggcataatc ccatggttgc agataagtga gataggtcaa
    30901 caaacgccct gacaaaatct tggcaaaact aatggccgca cttccataga cacgaacacc
    30961 aagaaccgct cggctcaaat cagccagccc ccattcattg gtttccagca taccactatt
    31021 ccctgcaatg agaaaatctc caagtggttt agttttaaaa ggagctaggg gcctatcatt
    31081 tagacaaact ggaaattccc caccaccgtg gtaacaatcc cctttgacca catcataaat
    31141 cagaccaaac tgtccctgac cattttcaaa ataagccatc ataacagcaa aatcttcctg
    31201 ctgggctaca aaattattgg taccatcaat gggatcaatg acccaaacct tgccctcttg
    31261 aaccgaggct cgcagacaac cttcttcagc acaaatctta tcctcaggat aacgggacaa
    31321 aatctcacca accaagagtt cctgaacttc tttgtccagt ctggtcacca aatctgttgg
    31381 agaggacttg gtttcaacac gcaagtcttc ctgcatatgg tcaagaatgt actgacctgc
    31441 tttcttaaca agctctttag caaattcaaa tttactttcc aagagaaatc tttccttcct
    31501 ctttttcttt ggcagcctga actgctcggt aaagtgaata gccactaacc gtttcaaatt
    31561 ctcgtcccaa acgtttctct tcgctcttgc ttggcacgac cgctttgaat cccttatagg
    31621 agtccagtaa ctttttagcc tctactttgc cttcataggc agcttcaaca tcattaaaaa
    31681 aagaaagcac tgaagcaagt tcttcagtgc tccacgacaa atctagtggg taactatact
    31741 gtttgttcat taactaatac cagctctcat tcttgcttct tttagttctt gcttacgata
    31801 actacgaggg agaaaagcac gaatctcatc ttcattaaaa ccgatttgca tacgcttggc
    31861 atcaataata attggacgac gcaaaagact aggatactgc tcaatcaaat gaagcaattc
    31921 cgataccgaa atactctcta catcaatatt caatttttga aaaatttttg aacgagttga
    31981 aatgatgtca tcagtaccat tttcggtcaa ggaaaggatg tgttgcaatt cttttcttgt
    32041 taaaggactg gtcataatat tgtgttccac aaagggaacc ttatgttttt ctaaccaggc
    32101 cttagcctta cgacatgatg tacagctcgg tgatagaaat agtgtaatca tgcttttctc
    32161 ttcttatcta tactttgcta cttctattat acaaaaaaat aaggcgcttg actagggatt
    32221 tttagaaaaa aagcctattt tttcaagaaa aataggctgt ttgcgaacga tt
//
LOCUS       DAVDZK010000025        31637 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVDZK010000025 DAVDZK010000000
VERSION     DAVDZK010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31637
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.026"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(52..768)
                     /locus_tag="VUX16_001350"
     CDS             complement(52..768)
                     /locus_tag="VUX16_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET8124307.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKSQGATPKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYEIQNKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AESGLSLEEYYGFEGGDYVD"
     gene            complement(771..1241)
                     /locus_tag="VUX16_001351"
     CDS             complement(771..1241)
                     /locus_tag="VUX16_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET8124308.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGYGLNGRGPVWWIPFEEMIAEICQSKPDEIKRLVERLSSEVDKLLEIKE"
     gene            complement(1243..2280)
                     /locus_tag="VUX16_001352"
     CDS             complement(1243..2280)
                     /locus_tag="VUX16_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET8124309.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVVFA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(2378..3703)
                     /gene="brnQ"
                     /locus_tag="VUX16_001353"
     CDS             complement(2378..3703)
                     /gene="brnQ"
                     /locus_tag="VUX16_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET8124310.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAVYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEEMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVKFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(3874..3966)
                     /locus_tag="VUX16_001354"
     CDS             complement(3874..3966)
                     /locus_tag="VUX16_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET8124311.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(4009..4161)
                     /locus_tag="VUX16_001355"
     CDS             complement(4009..4161)
                     /locus_tag="VUX16_001355"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET8124312.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(4321..4899)
                     /locus_tag="VUX16_001356"
     CDS             complement(4321..4899)
                     /locus_tag="VUX16_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET8124313.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(4953..6353)
                     /gene="pepV"
                     /locus_tag="VUX16_001357"
     CDS             complement(4953..6353)
                     /gene="pepV"
                     /locus_tag="VUX16_001357"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET8124314.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKVDAEHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFDFAGPAKDYLDIAGKILLNDHEGESLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(6366..6971)
                     /locus_tag="VUX16_001358"
     CDS             complement(6366..6971)
                     /locus_tag="VUX16_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET8124315.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTNLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            7142..7942
                     /locus_tag="VUX16_001359"
     CDS             7142..7942
                     /locus_tag="VUX16_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET8124316.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGYYLPDQSQLQ"
     gene            complement(8128..8961)
                     /locus_tag="VUX16_001360"
     CDS             complement(8128..8961)
                     /locus_tag="VUX16_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET8124317.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKNQGVSKYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGAIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLSSLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(8951..10798)
                     /gene="uvrC"
                     /locus_tag="VUX16_001361"
     CDS             complement(8951..10798)
                     /gene="uvrC"
                     /locus_tag="VUX16_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET8124318.1"
                     /translation="MNNLIKPKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVRAANEIKRLLDRIFPFRKCTNLPSKVCF
                     YYHIGQCMAHTICKKDEVYFKSMAQEVSDFLKGQDDKIIDNLKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQISTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREGLTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQETEILPQVAEERVDYQMEGNYNEP"
     gene            complement(10837..11526)
                     /locus_tag="VUX16_001362"
                     /pseudo
     CDS             complement(10837..11526)
                     /locus_tag="VUX16_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
     gene            complement(11605..12837)
                     /gene="murN"
                     /locus_tag="VUX16_001363"
     CDS             complement(11605..12837)
                     /gene="murN"
                     /locus_tag="VUX16_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET8124319.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     IKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(12842..14062)
                     /gene="murM"
                     /locus_tag="VUX16_001364"
     CDS             complement(12842..14062)
                     /gene="murM"
                     /locus_tag="VUX16_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET8124320.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDAGQARVPLAATLTLEFGQTSVNLYAGMDEDFRRYKAPILTWY
                     ETARYSFERGILWQNLGGVENNLDGGLYRFKANFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(14174..14953)
                     /locus_tag="VUX16_001365"
     CDS             complement(14174..14953)
                     /locus_tag="VUX16_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET8124321.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNVTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQDFSPESQNLG
                     TPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEGFLTTLPIDFKLEERLT"
     gene            complement(15022..16683)
                     /locus_tag="VUX16_001366"
     CDS             complement(15022..16683)
                     /locus_tag="VUX16_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET8124322.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(16858..19080)
                     /gene="recJ"
                     /locus_tag="VUX16_001367"
     CDS             complement(16858..19080)
                     /gene="recJ"
                     /locus_tag="VUX16_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET8124323.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEEM
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPYRDLFIAFGGHAGAAGMTLEVEQLSDLSQILEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQYFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYRFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESHIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            19356..20024
                     /locus_tag="VUX16_001368"
                     /pseudo
     CDS             19356..20024
                     /locus_tag="VUX16_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            20022..20708
                     /locus_tag="VUX16_001369"
                     /pseudo
     CDS             20022..20708
                     /locus_tag="VUX16_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            20721..21398
                     /locus_tag="VUX16_001370"
     CDS             20721..21398
                     /locus_tag="VUX16_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET8124324.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYSLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYTAEVIRSGIQSIPSGQMEVALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGVALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            21408..22067
                     /locus_tag="VUX16_001371"
     CDS             21408..22067
                     /locus_tag="VUX16_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET8124325.1"
                     /translation="MESILEVLSPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            22361..23551
                     /locus_tag="VUX16_001372"
     CDS             22361..23551
                     /locus_tag="VUX16_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET8124326.1"
                     /translation="MKSIKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTAHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FVSIILVAYLGKYIQYEAWRWIHRMVYLAYIFGLFHVYMMMGNRLLTFNLLSFLVGSS
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQAGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQVGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYNFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(23871..24752)
                     /locus_tag="VUX16_001373"
     CDS             complement(23871..24752)
                     /locus_tag="VUX16_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET8124327.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(24893..26221)
                     /gene="vncS"
                     /locus_tag="VUX16_001374"
     CDS             complement(24893..26221)
                     /gene="vncS"
                     /locus_tag="VUX16_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET8124328.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTKNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQFF
                     SGNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(26218..26874)
                     /gene="vncR"
                     /locus_tag="VUX16_001375"
     CDS             complement(26218..26874)
                     /gene="vncR"
                     /locus_tag="VUX16_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET8124329.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(26923..27006)
                     /gene="pep27"
                     /locus_tag="VUX16_001376"
     CDS             complement(26923..27006)
                     /gene="pep27"
                     /locus_tag="VUX16_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET8124330.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(27153..28532)
                     /gene="vex3"
                     /locus_tag="VUX16_001377"
     CDS             complement(27153..28532)
                     /gene="vex3"
                     /locus_tag="VUX16_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET8124331.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSFKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIDTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AVQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIVFVLALVLVVAVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(28584..29231)
                     /gene="vex2"
                     /locus_tag="VUX16_001378"
     CDS             complement(28584..29231)
                     /gene="vex2"
                     /locus_tag="VUX16_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET8124332.1"
                     /translation="MTLLQLQDLTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(29358..30635)
                     /locus_tag="VUX16_001379"
     CDS             complement(29358..30635)
                     /locus_tag="VUX16_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124333.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VETNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVS
                     GEQSVERDDLSAADKNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHGKIALDAGQSEAGKGQTVEFEIVGIFSGKKQEKFTGLSSDFSENQVFT
                     DYDSSQTLLGNSEPQVSAARFYVENPKEMDGLVKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKTSIFLQF
                     CLEVVLVSLGALLPAFVVGNAITSYLLQTLLASGEQASLQDTLAKASSLSTNILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(30786..31343)
                     /locus_tag="VUX16_001380"
                     /pseudo
     CDS             complement(30786..31343)
                     /locus_tag="VUX16_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000035094.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         8940 a         7260 c         5910 g         9527 t
ORIGIN      
        1 tacgcacggt aaggcgacgc tgacgtggtc tgaagagatt ttcgaagagt attaatcgac
       61 gtagtctccg ccttcaaagc catagtattc ttccaaactg agaccactct cagcaatttc
      121 tttagcttct tttcctacat aacgcaggtg ccattcctca gccatatagc ccgtttcttt
      181 ttctttacct ttaagataac ggacaacaaa accataatca gccgcatggt ccaggagcca
      241 ttgagctgct ttttcttctg tcaccaaatc accatcagtc ccaataacat caaaggccaa
      301 gcctgtttgg tgttcactat agccaggtcg ggcagagtaa cggtcggcag cttctttccc
      361 gtcttgattg acataatctt gatagagctt gttctgaatt tcataacttc taaagccact
      421 gtaatggtca ctgattggga aacctgcctc ttgcatcgct ttgatgagtt tgaccaactc
      481 tgccttggct gttggatttt cccctggatt atagtcttta gacaatggat agtgtttatt
      541 tgctacgatg atttcatcgt atttaccctg aatgctgtaa tagtctcctt tgttaaccac
      601 ttctgctttt tttggggtag ccccttgaga cttgcttccg actgttccat cagccttggc
      661 tgtttgttct gtcttagctg ctccatcttc attttttgct ttttcttgtg aacaagctgc
      721 tagactcaag gctagcaagg ctgtcaagac aaggtatctt tttttcatct ttactccttt
      781 atttctaata gtttatctac ttctgatgat aaacgttcga ctaatctttt aatctcatca
      841 ggttttgatt ggcagatttc tgctatcatt tcttcaaagg gaatccacca tactggacca
      901 cgtccattga ggccataacc attcatatca cctcttcgtc taggaaacag atgccaatga
      961 agatgggcat cgccatttcc tagcagttcg atattcattt tctcagcagc aaaggccttg
     1021 gcaactgcct cttggaccac actcatttct tctagaaaac ggagtcttgt ctcctttttc
     1081 aaatggtgca attcggtgac atgttccttg gctagaaaga gactatagcc tgcaaaatac
     1141 tggtggtctc caatcacaag atagcctgtt tccaactctt tgacaaaata gggattttct
     1201 cccttcttga tgagctcaat tctctgacat ataaggcaca tatcaatcta ctaaattgct
     1261 tctaagatag gcatcgacca ttcgttctgt tgcgaccacc gagtcaatat gagtgcgctc
     1321 ataagaatga ctagactcga tacccgcacc aagaagggca tgcttgacct ctgcccctgc
     1381 agacatagcc gctgaagcat ccgaaccata aaatggatag atgtccagct taaaaggaat
     1441 atcttgctct ttagcaaaga caaccaagtg ttgacggaag tcatagtgat aaggacctga
     1501 agcatccttg acacagatag atactgtgta ctcatctgtc tgctggtcat ctcccatagc
     1561 tcccatatcc acagccagat attctactac ctgagcagga atgttagaat tagcaccatg
     1621 tcctacttct tcaaaaactg aaaaagcaaa atgagttgtt actggcaatt caatcttctc
     1681 tttcttataa atacgaagca ggttgagcaa aatcgctgcg ctgaccttat catccaaatg
     1741 acgagacttg ataaaacctg tatcagtcac aacagttcgt ggatcgaagc tgataaaatc
     1801 accgacctca atcccaagag cacgagtttc tttttcattg cttactttta catccaaacg
     1861 cacttccata ttgtcctgcg tgcgttctgc agttcctgca tccttgtaga catggcaaga
     1921 agtttggtgg atgaggatgg ttcctgatac cttttgacct gtgctagcca catgaacggt
     1981 acagttttca ccttcaatca tgttccaagg aaaaccaccg atacggtcca atttaagacg
     2041 accatctggt ttgacagcac gaacaatagc acccagcgtg tccacatggg cagtcacata
     2101 gcgatgttgc tcatcatttt gacctttgat ggtcacattg acaccaccct tggctgtgcg
     2161 aactggctgg taaccaaaac cttctagagt cttgactaaa taattcgaaa tttcacgagt
     2221 gaagcccgtt ggcgatgcga tggctgtcag ttctttgata tattctactg tttgattcat
     2281 ttcttcacct ctttcgctac ctattataac acatttatca tcggataaaa aaagaaaatc
     2341 actcctgtag acttggctac aaaagtgatt taagtgatta ttccatttca aaaacatcgc
     2401 tttcttgctt gtttggtaga accaatgaga gcaagattcc aacaatggct ggcaccaacc
     2461 atgggagaga tgccttggca aaaggaagaa cgctaacaag atttgcaaga aacttaacct
     2521 taaacgagct tcctagtacg cttgcaatgg caataactgt aaccacagca attgtcaact
     2581 gcatacctgg ttttgaaagg gcaacaaatt tgttgacaat gacaatcata acgatagcaa
     2641 tcgtgattgg gtacaagata accagtactg gaattgagta cttgataatc gcatcaagac
     2701 ccaaattggc aatagcaaat ccaatcaagg taaaggctgt cgcataaacc ttgtagctga
     2761 tttgtgggaa gcgctcatta aagaactcag ctgttgacac aatcaaacca acagtcgttg
     2821 tgaagcaggt tacggtaacc atagctgcaa ggaagagttg agctgttgag ccaaagattt
     2881 cttgagtggc ttgtgacaag atgtaaacac ctggtgtccc acccttcatc tcttcagctg
     2941 gtactgggaa atgatttcca agaaaaccta aaccgatgta aagagcgctg aaggcaaggg
     3001 caacaacgat accaacaacc caaatagttg aaatgtattc tttcttactt gaaaatccaa
     3061 gttgtttcaa ggtttgaact gcgattacgc taaaggccac tgaggcaagg gcgtccaagg
     3121 tattgtaacc ttctaggaaa cctgtaccaa aggcagaagc ttgataaaca gctgaagcag
     3181 cttgaggact tgttccacca tatttgatag ctcccagaac gaccaagata acaatcaaaa
     3241 ttgcaaagac tggcgttaaa atacgtccaa tgcggtctaa gatttttgat ggattaagcg
     3301 aaatcaaata ggctgccgca aaatacagaa ccgtaaatac aatcaagcca agtcctttat
     3361 ttgcatccga caaaaggggg ctaatcccta cttcgtaagc tgttgtagca gtacgtgggg
     3421 tagcaaagaa tggaccgatt gacaagtaaa gaactgagag gtaaagagtc gcaaaccaag
     3481 gcgctatctt cgttgaaatc tcgtagatat atcctttagg atttagcgtt ccaataataa
     3541 gggtcaagac ggcgatacca acgcctgaaa agacaaaacc tgcgatggca ggaagaaaat
     3601 gttctccaga tagagcacct agagaaggcg gaaaaatcaa gttccccgca ccaaaaaata
     3661 ttccaaacag gagcaaacct gttagggtac cttttttagc cataaaaatc tccttcatat
     3721 ttataaaata ctgacctagt ataccacgat taggagtctg aaaaaagcat cacgaggcaa
     3781 atattaaatg ttttcaattt tcttaaaaat aagaattatc taaaaataaa actctcctac
     3841 ccagtccaca ccaagtagga gaaatgcaaa attttaaagt tcttcaaagg ctaacatgcc
     3901 accctggaca ttgataacat tataaccttg ttctaatagg aattggcaag cacgcgccga
     3961 tctcattcca gatttgcaaa taatataatg caagcgatct ttgtccaatt aatcataact
     4021 atcagccaat tgactaagcg gtaggttgtg ggcaccttct aaatgaagag ctgcaaactc
     4081 atccacttct ctcacatcca ctagagaaag ctggtcgttt tggtaaagct ggtaaaatgc
     4141 gtcaaaggct atttctttca ttctttttct tctaatactc ttcgaaaatc tcttcaaacc
     4201 acgtcagcat cgccttaccg tgcgtatgtt accgacttcg tcagttttat ctgcaacttc
     4261 aaagctgtac tttgagcagc ctacgactag cttcctagtt tgctctttga ttttcattga
     4321 ctataaaatg gttttaattc tttttttcaa atctggcact acttctgcct caaaccaagg
     4381 atttttggcc atccagattt gatttcgtgg tgatgggtga actagcggaa aataggctgg
     4441 cagatagtct ttataatgtt tcaccctctc cgttaccttc ccactgattt tctcctgtaa
     4501 atagtaggct tgggcatatt gcccaatcaa gagggttaac tgaatatcag gcaattcctg
     4561 taagagctgc ggatgccatt tttctgcaaa acctgtacga ggcggaagat cacccgactt
     4621 gccatgtcct ggaaagtaga aatccatagg caaaacagca aaataacctg aattgtaaaa
     4681 ggtatcttca tccacaccta gccagtcccg caagcggtca ccacttttat ctttccagta
     4741 aaggcctgct tcttgagttt taagtcccgg agcctgaccg atgatattga tgcgagcagt
     4801 ttttggcgct gcaaagagag gctcaatgcc acgctctgta tagctggcat tctgcgaatc
     4861 cgccatgata gcctgtttga ttctttcgat ttgagacatc tactttccct ccaaaaagaa
     4921 gtccaagcat aagatctcag acttctatcg ttttatttga tcaattcgta aatagcttcg
     4981 gcataaattg ctgctgctcg gaagagatca tccaaggcaa taaattcatt ggcttggtgc
     5041 atggtatcaa ttgagtctgg gaacatagca ccataggcaa ctccgcgctc taacaagcga
     5101 ccaaaggttc caccaccgat gacttgttca tgacctttaa ggcctgtttg tttttcatag
     5161 acattcaaca aggtttgcac aagtggatct tccattggca catagtgagg cgtgtgaccg
     5221 tgttcagaca ggctaacaga aacaactggc aagttttcaa ggattgactt gatttgttct
     5281 ggacttgttc cttttggata gcggatgttg agagcaatgg tattatcagc acttgtttca
     5341 tcgaagcgga agacgcctgc attcatagaa agggcaccca tcttttcatc cacatgagcg
     5401 atcttaagac tttcaccctc atggtcgttc aagagaattt taccagcgat gtcaaggtag
     5461 tctttggctg gaccagcaaa gtcaaactgg ctaaggaaga gggctaggta agtcgcacca
     5521 ttgacacctg aagcaggcat agcaccgtgg gctgatttac caatgatcgt caccttgtat
     5581 ttgccagctt cttcttggag ttctcctcta agtttgtgtt ctgcaacaaa ggcatctagt
     5641 ttagcttgca aatcagccaa atcacctgaa acgactgctg ttgctgattc tggtaccata
     5701 ttttcacgta aaccacctgt aaagctgtga agacgggcag cacctgtatt ttctcctgca
     5761 aagtggaggt attccgtgat atttcctttt tcaccattga tgatagggaa ttcagcgtct
     5821 ggagagaaac cgaaatctgg tttggcaagt cctacgtgct caaagtagta gtccatgtct
     5881 gcccagcctg attcttcgtc tgttccaacg atgaagcgaa ctttcttaga agttggaaga
     5941 cccaattctt tgatgatttt caaaccatag taacaagctg ttgtaggacc cttatcgtcc
     6001 gaagccccgc gcgcataaag gcgaccatct ttgatagttg gtgtgtaagg atctgtgtcc
     6061 caaccgctac cagcaggcac cacatccata tgggcaaaga ttccgagaac ttcttctcca
     6121 tcaccaaact caaaatgtcc tgcgtagtta tcgacattct tagttgggta gccatcacgg
     6181 tctgcgattt caaggaattt ctccaaggct tttactggac caggcccaaa tggatgttca
     6241 gcatcaacct tgctgtcatc acgttctgaa ttgatttcca aaaggctaaa caagtcagcc
     6301 aagaggtctt ctttgcgttt ttctacttct gctgtaaaat caattgctgt cattttttct
     6361 tctttctatc ttttctcgat gatttcatct actggcaagc ggtagcttgg ttccaatttt
     6421 tcgtctgtat aacccactgt gatcaagagt tctgggcgga aacggtcttc aatttccaaa
     6481 acctcattga cttttgattt gtcaaatcca agaataatgt tagaaccaat tccttggtct
     6541 gtcaatgcaa gaactaagtt catggcaacc aaacctgcat tgagagctag gtagtcgctg
     6601 acttgttgct cactgtaacg ggcaaactca gctggcagat ttttcataaa atattgaagt
     6661 tgctcttcag aaaagttatt agcaccacca acacgggcaa tcttacgagc acgtttggct
     6721 aagttcgtat ctgtaaacaa ggcaatggtt acaggcgctg atgatacctg ctcaaagttt
     6781 gaaccataag ccaactttgc cagttcagca tttttctcac gaacaactac aaatttccaa
     6841 ggctggctgt tgtgggcgct tggcgccaag gttgcaattt cgatagccgt acgcacatct
     6901 tttggatcaa caggcttatc agtgaaatgc ttggtcgcat gacgtttttt atttaattca
     6961 agaaatttca taatcgattt ccttttctaa ttctactgct tccattctac cataatttga
     7021 aagagcttgc agggattttt catgattaag tttttctatc acagacataa aagatatata
     7081 ttggtttatc aggaacattt ctgataaact agcaagtact ttacatttga atggagacag
     7141 tatgaaaaaa tttagcctat tactagctat cctaccattt ttggttgcct gtgggaatca
     7201 agctacaccc aaagagacta gcgctcaaaa gacaatcgtc cttgctacag ctggcgacgt
     7261 gccaccattt gactacgaag ataaaggcaa tctgacaggc ttcgatatcg aagttttaaa
     7321 ggcagtagat gaaaaactca gcgactacga gattcaattc caaagaactg cttgggagag
     7381 catcttccca ggacttgatt ctggtcacta tcaggctgcg gccaataact tgagttacac
     7441 aaaagagcgt gctgaaaaat acctttactc gcttccaatt tccaacaatc ccctcgtcct
     7501 tgtcagcaac aagaaaaatc ctttgacttc tcttgaccag atcgctggta aaacaacaca
     7561 agaggatacc ggaacttcta acgctcaatt catcaataac tggaatcaga aacacactga
     7621 taatcccgct acaattgatt tttctggtga ggatattggt aaacgaatcc tagaccttgc
     7681 taacggagag tttgatttcc tcgtttttga caaggtatcc gttcaaaaga ttatcaagga
     7741 ccgtggttta gacctctcag tcgttgattt accttctgca gatagcccca gcaattatat
     7801 cattttctca agcgaccaaa aagagtttaa agagcaattt gataaagcgc tcaaagaact
     7861 ctatcaagac ggaacccttg aaaaactcag caatacctat ctaggtggtt attacctccc
     7921 agatcaatct cagttacaat aacactcttc gaaaatctct tcaaacaaac cacgtcagct
     7981 ttatctgcaa cctcaaagct gtgctttgag caacctacgg ctagcttcct agtttgctct
     8041 ttgattttca ttgagtataa gatatactaa aagcgattgg accagccaat cgctttttta
     8101 gtttgcattg gctattttag gaaactctta caaaaaatca aaaaaattct tcacatcctc
     8161 tacataccca tgcttttcta ttaagctgga taataattcc agattgtgcc cctgatagtt
     8221 atcgtcacga cgcagttctt catacatttc gataaaggga agccccttgg acttggccaa
     8281 ttctaactca gcttcgtaat cataagcaac tttacgaaat tggatattga gtaattcccc
     8341 atcttcaact tctatcacgg catactgggc acggtgattt tttaacgcct cccaattaaa
     8401 atagggcatg ccaatcgccc ctggattgat gatttgttgc ccttgacttc cataacgaag
     8461 caactgcttg tgaacatgac cataaactgc cacgtccgtt tccgcatcta gcagttggtc
     8521 aaatttctct gtatcattct caactagcaa gtcaccacca tagtttttgt caggtaaatt
     8581 atgagagata gaaaagcgca atccgtcaat ttctttcttt tccagcaaag gcaagcttcg
     8641 tagccagaca atcgttgcag gatccattcg ctccatcaaa aactgggtca tgcgcattga
     8701 ctggatttct ttcggatatt ccaaaccata ttcgccatcc aagacctcaa ggacacgatc
     8761 atcccaattg cctcgaacac ttgctgtgat aggaaggtcc tttagcaggg caactaagtc
     8821 atttgcgcct ggaccaggaa gaaaaatatc tcccagaagc cagtatttac tgactccttg
     8881 atttttagca tctgcaatca ctgcttctag cgccgtcgca ttgccatgaa tatctgataa
     8941 aattgcgatt ttatggttca ttgtagtttc cttccatttg gtaatctact ctttcttccg
     9001 ccacttgagg caagatttct gtttcctgcg ggttcaattt tctttgcaca gcctctgcaa
     9061 ctgctcttgg taccccaact tcgacaatct catccacact ggcttccttg attttagtca
     9121 aagacttgaa atgcttcatg agattctgct tgcgtttagg tcccagaccg tcaatcccat
     9181 ccaattgaga tgaaaaggaa tttttggagc gcagttggcg gtgaaaggtg atggcaaagc
     9241 ggtgcacctc atcttgaatg cgttgaagga ggaaaaattc ttgagaatta cgagacaagt
     9301 ccaccacttc cagcggatct ccaaagagca attcatgagt ttggtgctta tcattctttt
     9361 gcagacctgc aattggaata tccaagccca gttcctcttg gataacctgc ttagcgatat
     9421 tgacttgacc ttgccctcca tcaatcacaa tcaaatctgg cggagttaaa ccttctcttt
     9481 gcactcgacc ataacgtctg cgaatgactt ctctcatact ggcatagtcg tctggtccaa
     9541 ccacagtctt tattttatac ttacgataat cttttttact tggtttgccg ttgacaaaga
     9601 ccaccatagc tgaaacagga ctagtcccca tgatattgga attgtcaaag gactcgatgc
     9661 gaactggggt tgagatttga agcaagcgtc ctagattttc aatagctcct tgggtcttct
     9721 cgacagattt ctctagcagg ttgaacttct gctctaggct aacacgggca ttttttatag
     9781 ctaaattgac cagctgcttt ttctctccac gttgaggctt aagaatcttg gaatccacca
     9841 aagccttgac agcttcttcg tcaatatcct gcggaatcag tacctcattg ggaactagat
     9901 gagatttttc ttgatagaat tgtcctacat aggtcaaaaa atcctcatct ggatcattga
     9961 agtaggggaa tagattgaca tcgcgctcga tgagcttgcc ctgacgaaca aagaaaactt
    10021 gcacacacat ccagccctta tccacatagt agccaaagac atcgcgattt tggagatcct
    10081 tagccatgac ccgttgcttg gttcgaagcg ttccaatagc ctgaatcagg tcacggtatt
    10141 ccgccgcacg ttcaaactcc atagtctggg ccgccgctgc cattttgccc ttgaggttat
    10201 caatgatttt gtcatcctgc ccttttaaaa agtcagaaac ctcctgagcc atagatttga
    10261 aatagacctc atctttctta cagatagtat gggccatgca ttggccgata tggtagtaaa
    10321 aacaaacctt agaaggaaga ttggtacact tacgaaaagg aaaaatccga tccagtagtc
    10381 gcttgatttc attggccgcc ctcacatctg gataaggtcc aaagtagaga cctccgtcct
    10441 tcttgacctg acgagtgata atcaaacgag gatagcgctc attagtgatt ttgatgaagg
    10501 gataggactt atcatccttg agcatgatat tgtatttagg tttattttcc ttgatcaggt
    10561 tgatttctag gagaagtgcc tcaatattag actcagtaac gataaattca aaatctacaa
    10621 tttcagacac caaagcctct gttttggtat catgacttcc acggaaatag gaccgcacgc
    10681 ggttacgcag atttttagcc tttcctacat agataatggt gccgttttta tccttgtgaa
    10741 tgtagcaacc agggctggtc ggcaagagct ctagttttgg tttaatcaag ttgttcatag
    10801 ttccattata gcaaaaaagt agggaaagat agtaccctac tcactagtct catatatttt
    10861 tcggaggttt gcaacatcct cttcctggat accataaaag gaacctgctg gttgcatgac
    10921 agacttctca tctgtatggt ccaagccaat cgcatgacct aactcatgtt ctgccgtatg
    10981 gacaaggcgt tcataggaat agccatagta tggattggac aaataataat gattcaaccg
    11041 caccgttacg gacaagaatt gccctgttaa gagattagtt tgactttctg cctctcctgc
    11101 cacaggagtg cctccgtcgt tcatctccgt agccgtaata tccgccttac tagactcagt
    11161 cacgagttca aagttaaaag caccaatttg attccagttc tggattgctt ctaaataagc
    11221 ctcttgaaag cgtgaatcca tctggggatc caggtaaata cgagcagagg cctgtggcca
    11281 ccttccttca gaatgctggt gactatctgt ctggcttaac ttaggcagtt gccctgtttt
    11341 ctctcattgg tcaatacttt gttgaccaat ttttactgac cgttctgctt gctttagcgc
    11401 tccttgaaaa tccccgttca gataccagag aagtccgaaa gcaagcacac ataagagcac
    11461 aactatccaa aacaaacgcc acacaaaaga aaagaaagcc cctatcaaac gaaaaagcca
    11521 gcgcatgtct ctccaccttt ctagcaaata agaattattt tactaaaaga agctaaaaga
    11581 aatctaaata ctgacttttt catcttaacg tcctactatt tttttgagta actggatagc
    11641 tttgtatttt aaaggcgatg gatggtaacg gaaagtacct gctttgcgta caatatagcc
    11701 attaaaattc tgtttaaaac gcaaaacacc atcacttcca tcaaaaatcc cttgaatgcc
    11761 taggaagttg tatttaggta ttccacgttt tatgctttcc aacataacat atttttgaag
    11821 cagtgcaggg gcatagaact tattaaactc agtgtaggaa ccactaaaga gataagtcgt
    11881 ttcctgaggc atataaacaa ataaactccc agctaaaaca atatcttctt ctccatattt
    11941 ttcaatcaag tctcgcgctt ctgcttttcg aacttcaaac gtttcaaatt gactagaata
    12001 ttctctcagt tgattttgtt ttttctcaga atgaggattt ttactcaaat caagtcgcaa
    12061 cttgtccaag ttttcttcta gtttactttg ttcaccttgc aatttgctca tatactccga
    12121 aaaatttaag cttgctatga gaaactccgc ttgttctcca aaagtatcat aaaaatgctc
    12181 ataatattct aaacttttat cactatattc tctacgttca gaggtttctt ttgttatatt
    12241 cttaaaaatc gatagttctt cacgttttaa ctttttcaac cgaatgccaa aggtttcagc
    12301 ctttttcacc aagggtttac cctttttgct aaaactttta agcaaactct tttcagttaa
    12361 ttcagttaaa tctttatagt ataaccaatc tggttctcca cctgggtaac ctgttgttaa
    12421 gccatcaaat tgataaccta aatcagtcaa accttgaata atactttttt tctcagcatc
    12481 tattggatta ccttggctat caaaagtttg ataagtttca taaggtttta taagcaactc
    12541 taatacacca ttttgcttgg catattcttt taactctgca taaaaaactg gaagagcatc
    12601 ttgttgggta taaatcggcc ccgaattgag ttccatatgc agaccaccca gcatgggcaa
    12661 gctataaacc agagctgcaa cttgaatttc tccttcttgt ttcaaagcaa gataaacaat
    12721 tcgagcccct cttttttcta gcaaatcccc catctggaca gattgcataa aggaacgaga
    12781 agaaacctga tcagaataag tctgaaactc ttctttcgtg agtgttgtta gtgccatata
    12841 cttactttct atgttttttt cttaatgttt tacggaaatc aagagcaagt cttaacagag
    12901 gatagagagg atgagtgggc attgtaaatt cacccaagta ttcttcaatc gttggattaa
    12961 aattagcttt aaaacgataa agtccaccat ctaaattatt ttcgactcct cctaaatttt
    13021 gccataaaat gccacgttca aaggaatatc tagctgtctc ataccaggtc aaaatagggg
    13081 ctttatatcg tctaaaatct tcatccattc ctgcatatag attgacagaa gtttgtccga
    13141 attctaaagt caaggtagcc gctaaaggaa ctctcgcttg acctgcatct atatattcct
    13201 gcaagaaggt caattcctct aacaaacgtt ctttttcctt cttctgcgct tctacttttg
    13261 aagttcgagt cgattcagta aaggtctctt ccaaggctct gtttttcgct aactgttctt
    13321 ctaattcttg cgaacgttta gagacatcca aggttgccaa ggtgatatag gccttgtcct
    13381 taaaattatc taacaatttt ttataatagg cttcattcct caaatgaatc tcttttcgct
    13441 tctcagtttt tttcatcaac tccgaaaatg aatctaatag ttccagtcca ccatattgaa
    13501 tctcaagccc tttgtttcgt gctgttcgaa tagcctgttt tgttgacttg gaaagtttat
    13561 cttcttcaaa attttccttg tatatttttg cctgaatacg aggttgaatg gtgtctccca
    13621 tttcctccgt ttttcctgac caccttactc ccatttgttg caaactatca ataatagcca
    13681 gattttcagg aaattctgtc ttttcctgat tgattaaact ttgagatagg caaatacttg
    13741 ggtcaaaagt cacaaaaacc gctctcttac tgcgagcata ggacttaata gactgaatgg
    13801 caaaattcaa gagttcttta tccccataat ccaatatagg tcctcttggg atgtaaaaca
    13861 ttttatagcc tagcggaaga gttctaatca aaatactagc tgtcgccagt aatttttctt
    13921 ccctgtaaac accaaacttc tcatgttgcc aattagactt aacttcctcc caagcactac
    13981 tttgtaatac attggctaat tcatgttctt tgacaaactg atcatattct aatgtgggaa
    14041 tgccaatttg ataacggtac atttcctact ctctttcctc cagtatttta ttactattct
    14101 actactttcg tttgaaaagt ctagtgaaaa catattttat tttagttcta ctccccctat
    14161 gctgaagttc aaactaagtc agtctctctt ctaatttgaa atcaattggt agggttgtta
    14221 aaaaaccttc caattgtttt tcccaataat accactcgtg agttccagcg ctatggctat
    14281 aggtcacatc aaaacctagt tttttgagat ttttcactgc gagattattg gcttcgtaca
    14341 agaaatcctg ttcgccacac cacgcccaaa gtttggtctt tttatccgat tttttagcca
    14401 gactttcaag agaataggga ctagttgtcc agtctttaat ctctccaaaa acacctctcc
    14461 agtatgctgg cgttcccaga ttttgactct caggagaaaa atcttgaaag ctcaatgcac
    14521 ctgaaaagct agctgcatga gaaaaacgat ttgtcgtaag agccagtttg aagcagccgt
    14581 agcctcccat agaaagacca gcgataaagg tcttttcacg cttgctagtc acattaggga
    14641 agaagcgttt cagaacctgt ggcaattcct ctgctagagc cgtgtagtag tcaaaaccat
    14701 actgggtatc ggtgtaccaa ccattgctgg tattgggcat aacaacgatg agattagttc
    14761 ctcgaagcaa gcgttctaca ttggtccgct taagccaact attatgattt ccagacatcc
    14821 cgtgcaaaag gtacaagacg ggaatatctt cacactctgg ttcttccact cgattggcat
    14881 cagggtagag gacattcacc ccccactcca tatccaatac ttgtgagtaa tactcgattt
    14941 tcattactgc catgattttc tccttctatt tttctataag aaaaagccga aactcgactt
    15001 tctctctgtt tatttcaacg attattttgc ttccatgact actggtaaaa tggctgggcg
    15061 acgcttggtt tgatcaaaga ggtacttggt cagattgtca cgaaccttac ctttgagatc
    15121 tgcccagtca aagtcatctc cttgaagata ctcttctacc gtttggttaa tcaattctga
    15181 actttcacgg agaatatcgc gactcttctt gagataaaca aatccacgcg tgtgaacacg
    15241 agccctagcc acaattttct tctcacgacg gttgactgta atagccacga tgaaaattcc
    15301 atcctctgac aagaccttac ggtcacgaag aacaacattt ccaacatcac caatggcatt
    15361 cccatcaatc aagatatctc ctgctgaaac cgatccagct ggaacaaagt ctccattctc
    15421 gtaagccata gtcgtcccct ttttaggaat gaagatgcgt tctggcaaca tcccaactgc
    15481 catggcagcc ttagcgtgag catccaactc acgatactcc ccttggacag ggaagaggta
    15541 cttaggttgc aaaagattga tcatcagctg caaatcacgc acatttccgt gccctgatac
    15601 atgtaaactt tgggtaatca atttgacaac cccacctgcc tgataaatca tattttccac
    15661 acgcgcaaca aaggcttctt tagcaataga cggagccgta gcaatataga ccaggtcccc
    15721 atccttgatt tctacataac gatggcgacc aatcgacatc ttacgaagtc cattgatagg
    15781 ctcacccata cgacctgtct caagaataat caactcatgg tcttcaaagc gagacatatc
    15841 tttaggctta atcaaaagaa tttcgttggc taaagacaac ttcttaagac gaatcgctgt
    15901 gcggacgata ttttcaatat caaatcctgt caagacgata cgtcgacctg ttttatccgc
    15961 agcgtcaaaa atctgctgaa tacgagaaag attactggaa acagctgcaa cgatgatacg
    16021 accttcccag tcagcaatag tttgggtaat ttcatcccta acttcacttt cactagccac
    16081 ctgaatattg ctgtctgcat tggccgaatc actgaggaga gccaggacgc cgtcacgacc
    16141 aatctctgcc aaacgagcaa aatcagttgc ataagattca ctagccgttt ggtcaaattt
    16201 gaagtcacct gtataaacga tgcttccttc cgatgtcttc aagacaattc ccagactctc
    16261 tggaacggag taagtcgtag ggaagaagga aaccactgtc ccaccaaaat caatctccgt
    16321 attctcatca atgacatgga aatcattaaa tttcttaacg gcatcatttc ctttgacaaa
    16381 gagctttgcc aactcaatgg tcaactcaga cccaaataca ggaactttag cctctgccaa
    16441 gagataaggt agagcaccaa tggcatccgc atgcccgtgg gtcaagaaaa ccccagcaat
    16501 acggtcgcta ttttcaaaaa ggtaatccat gtttggaatc accacatcga cccctaattg
    16561 ttcattttca ggatatttta accctacatt caaaacaaaa atggactctc caatttcagc
    16621 aatgtacata ttttttccat tctcacgcac accaccaagt gttgttaaac tgatattact
    16681 catttttcct ccaaaatctt agtttatctt gattataggg caactctacc ctcttattct
    16741 aaaagttcta atactttcag ccgaatcttt tcctaccatt ataccatttt tttgatgatt
    16801 ttcaaaatga aggtctgttt tcaaaaaaga gttgatttcc caactctttc ctaacttcta
    16861 ctctttttcc atcaaaaaat cataaatttc ttgcaccgta cccagcgcca tcatttcttg
    16921 gtctttaacg gtttgtttga gattttggta aatatgactt tctcctatct cccgctttgg
    16981 cgcctcttta ttgactgtca tcacaccatc ttttatcgtc acaaagccta gttcttcaaa
    17041 tacttgaatc atcttgacca gcaagatttg ttgaatatta agatatgcag ccaaatcttt
    17101 cagcttgtag cgaatatcaa actctgggaa ccggtaaata gtcttgtaca atttggcaaa
    17161 ctgatctcta gtcccataac ctgtcagata ataggccttg tcaatatcat ttttgaaata
    17221 gacagcagag aaatactgtt cctgaaaaat ggtcttcagc tgagtaatat cctctggaat
    17281 gttttttacg acaacagctt cactagccgc aagatttggc agttctccag gaaaatccaa
    17341 gactggaaca ccttctggca agactgcatt ttttccacga atattaaaaa gttgaacacc
    17401 ttccactcgc gcatccacca tcatcaactg gagggcagtt tggccattcc attggttgac
    17461 agacaattta accgctaact ctagattctt ggtttgagaa aactctgtcg cccatctgcc
    17521 ttgaccaaag gctaccactt caaaactcgc ctcacccttg gaaattttca gctttagatg
    17581 ggcattacct gcccccatag tacgagcact ttcgacctga aaattcttga tataaaaaat
    17641 aggtttctga ttatccattc caaaaggagc taaacgttca aaacttttga ccgtttccaa
    17701 gctaagtgcc tccaaatcca actcttcatc taggtttaac ttattcttgc caccagcatc
    17761 tgcacctttt tcacgaacat aatcttccaa aatctgagat aaatctgaga gttgctcaac
    17821 ttccagcgtc atacccgctg cacctgcatg acctccaaag gcgatgaaga ggtctcgata
    17881 gggatccaga gcttcaaaaa tatcgaccgc ttccacacta cgagcactgc ccttggcacg
    17941 accgtcttct atattaagaa caatgactgt ctgtcccaat tcttccaata aacgaccagc
    18001 cacgattcct agaaccccag gattccagcc ttccttggcc aagacctgaa ccttcttctc
    18061 aggatccacc atggtcttgg cttcttcata gatagactga acgatttcct tgcgctcttc
    18121 gtttttctgg tgaatcataa gggcaatctc atgcgcttcc tcatcatcaa atccagtcaa
    18181 caaatcaatg gcaggattag gatcatccaa gcggcccaag gcattcaaac gaggagcaat
    18241 ctggaaacca accatttctt ctgttacttc gttggcagca atcccagcca tgtctagcat
    18301 ttcttgtaga ccaatacgct gagtgtggcc caacatttcc agaccatatt gcaccaaaat
    18361 gcgattttca tccgtcagac tcaccatatc agcaattgta ccaatagcga ccaaatcaag
    18421 caattccact tgcacttctt ctaacagggc acaagccaac ttgaaagcaa ctccacaacc
    18481 agccaaatat ttaaaaggat aatccgcatc tggatgttca ggatggacaa tagcataagc
    18541 atctggcagg gtttcaggca tggaatgatg gtctgtcaca atgacatcta ctcccataga
    18601 ctgagccaat gcaatagcct catgaccagc aaccccattg tccaccgtca caatcaagga
    18661 aattccttct tgctcgataa agtatttata aacactagca ttagggccat agccatcggt
    18721 aaaacgattt ggcaggtaaa ctcggcactc agcaccaagt tgttccaaac tttccttcac
    18781 aatagaagcc gaagtcatgc catccgcatc atagtctcca taaacgagaa tattttcccc
    18841 ttcttcaata gcctgacgaa tccgctccac tgccttgtcc atatcatgga gcagataagc
    18901 atcatgtaag tcctccaagg aaggttctaa aaacttcttc agactttctt ggtcctgaat
    18961 ccctctctca aacaataacc gagccacctc aggacccagt ccagccttct tggctatctt
    19021 tgtaaaatcc gcatcttcta cctgcagggc aaactgccat tcataagtag gtgttatcaa
    19081 aaagacatcc actctttcta agaattctat tgcttcatta taacatgatt tagacgtttt
    19141 ctctatccag attgcttttt tataacattt tatagtatat tgaaactaga atagtacacc
    19201 tctacttcta aaatattgtt agaaatcgat ttgactgtcc cgatcgattt gtcctgttct
    19261 tatctcacta tagtgatttt ttcagatatg gtttgacaag aacattcttt tattgtagaa
    19321 ttgtgttata aaatctaaca taaaggagat ctctcatggc tttagtagaa tttaaaaacg
    19381 tcgaaaaata ttacggagac taccacgcac tccgcaacat caatctccgt tttgaaaaag
    19441 gacaagttgt tgtcctgctt ggaccttctg gctctgggaa gtccactctt atccgtacga
    19501 tcaatggttt agaggctgtt gacaaaggaa gtctcctagt caatgggcac caagttgctg
    19561 gtgccagcca gaaagatttg gtacctcttc gcaaggaagt cggcatggtt tttcaacatt
    19621 ttaaccttta tccacacaaa actgtgttag aaaacgtgac acttgcgccc attaaagttc
    19681 taggaattga taaaaaagaa gctgaaaaaa ccgcccaaaa atatctggaa tttgtaaata
    19741 tgtgggacaa gaaagattcc tatcccgcca tgctatctgg tggacaaaaa cagcggatcg
    19801 ccatcgctcg tggtcttgct atgcatacgg aactcctcct ctttgatgaa ccaacatctg
    19861 ctcttgatcc tgagactatc ggagatgttc tagcagttat gcagaaactg gcgcatgatg
    19921 ggatgaacat gatcatcgtt acccacgaaa tgggctttgc tcgagaggtt gcggaccgca
    19981 ttatctttat ggccgacgga gaagttttag tagatacgac agatctggtt gtcggtgtca
    20041 aacaagacgt tcccaatttt ggttacaaag atcccaagac cggtacttat tctggtatcg
    20101 aaaccgactt ggccaagatg gtagctgatg aactcaaggt caagattcgc tatgtgccgg
    20161 ttacagcaca aacccgcggc ccccttctag acaatgaaca ggtcgatatg gatatcgcga
    20221 cctttaccat cacggacgaa cgcaaaaaac tctacaactt taccagtccc tactacacag
    20281 acgcttctgg atttttggtc aataaatctg ccaaaatcaa aaagattgag aacctaaacg
    20341 gcaaaaccat cggagtcgcc caaggttcta tcacccaacg cctgattact gaactgggta
    20401 aaaagaaagg tctgaagttt aaattcgtcg aacttggttc ctacccagaa ttgattactt
    20461 cccttcacgc tcatcgtatc gatgcctttt ccgttgaccg ctctattcta tctggctaca
    20521 ctagtaaacg gacagcacta ctagatgata gtttcaagcc atctgactac ggtattgtta
    20581 ccaagaaatc aaatacagag ctcaacgact atcttgataa cttggttact aaatggagca
    20641 aggatggtag tttgcagaaa ctttatgacc gttacaagct caaaccatct agtcataccg
    20701 cagattaagg aggataccct atgacagatt tatcatcttg gacagcctat tttcaggatt
    20761 ttggacaatt tttcaatggt ttcctcttta ctctcgccct agcgattgga tcctttatcc
    20821 tcgccatggt cttaggaatc ttctttggtg ccatgtcaac cagtaaacgt ccgattttgc
    20881 gaatcttagc tcgcatcttc gtggaatttt accaaaacac tcccctcttg gtgcagtttg
    20941 ttattgtttt ttatagccta cctcttatca gtgaccatac tatcatgatt ccgatttatt
    21001 ggacagctgt tctctgcgtg ggactctatc acggcgctta taccgctgag gttattcgtt
    21061 cagggattca gtctattcct agtggtcaga tggaggtcgc cttgtcgcaa ggttttacct
    21121 atatcagtgc catgcgcttg attatcttgc ctcaggcctt ccgcatcatt ctccctccat
    21181 tgaccaacca aattgttaac ctcatcaaga acacctctac tgtagctatc atctctggag
    21241 tagacttgat gtttgtgact aagtcttggt cggctctcaa cggaaactat atcccagcct
    21301 ttttaggtgt tgctcttctc tactttgccc tatgcttccc tgttgcccag tttggtcgca
    21361 agatggagca agccaacaaa aaagcctatt cactttagga ggttactatg gaatctattt
    21421 tagaagtttt aagcccagat aacctagtct ttatctttaa aggatttggc ttgaccctct
    21481 atatttctct gattgccatc atcctctcta ctatcatcgg taccgtgctt gccgtcatgc
    21541 gaaatggaaa aaatcctatc ttacgcatta tttccagtat ttatatcgag tttgtgcgca
    21601 acgttcccaa ccttctctgg atttttacta tctttttggt gttcaaaatg aaatccacgc
    21661 cagcaggtat tacagccttt actctcttta catcagcagc cttggctgag attattcgag
    21721 gcggtctcaa tgccgtagac aagggacaat acgaagcagg gatgtcacaa ggcttcacct
    21781 cagcccaaat cctctactac atcattctcc cacaagccat ccgcaaaatg ctgccagcca
    21841 tcatttctca gtttgtaacc gtgattaagg acaccagtct tctctactct gttatcgccc
    21901 tacaagaact ctttggagcc agccaaattc tcatgggtcg ttatttcgaa ccagagcagg
    21961 tcttcagtct ttatatcctg attgccctca tctacttcag ctttaaccta gccatttcga
    22021 gcctgtctca tatgctagca aaacgttggc aacaagctgc agaataatac tcttcgaaaa
    22081 tctcttcaaa ccacgtcagc ttcaccttgc cgtatatatg ttactgactt cgtcagttct
    22141 atccacaacc tcaaaacggt ttttgagcag cctgcgggct agcttcctag tttgctcttt
    22201 gattttcatt gagtataaac agccactctc cagttcaatt ggagagtttt ttataagaac
    22261 agagatttac acacctagat ttgacaccat acattttcta tgataaaatg taacaaattt
    22321 atttacaaca aatcgaaatc taaatgaaat ggaattttct atgaaatcaa tcaaaggact
    22381 actctttatc atagctagtt ttatcttgac tcttttgact tggatgaaca cttctcccca
    22441 attcatgatt ccaggactag ctttaacaag cctatctctg acttttatcc tagccactcg
    22501 tctcccacta ctagaaagct ggtttcacgg tttggagaag gtctacaccg cccacaaatt
    22561 cacagccttt ctctccatca tcctactaat ctttcataac tttagtatgg gcggtttgtg
    22621 gggctctcgc ttagctgctc agtttggcaa ccttgccatc tatatctttg tcagtatcat
    22681 ccttgtcgcc tatttaggca aatacatcca atacgaagct tggcgatgga tccaccgcat
    22741 ggtttaccta gcctatattt ttggactctt tcatgtctac atgatgatgg gcaatcgtct
    22801 ccttacattt aatcttctaa gttttcttgt tggtagctct gcccttttag gcttactagc
    22861 tggtttttat atcatttttc tatatcaaaa gatttccttc ccctatctag ggaaaattac
    22921 ccatctcaaa cgcttaaatc acgatactag agaaattcaa atccatctta gcagaccttt
    22981 caactatcaa gcaggacaat ttgccttcct aaagattttc caagaaggct ttgaaagcgc
    23041 cccacatccc ttttctatct caggcggtca cggccaaact ctttacttta ctgttaaaaa
    23101 ttcaggtgac cataccaaga atatctatga caatcttcaa gtcggcagca aagtaaccct
    23161 agacagagct tacggacaca tgatcataga agaaggacga gaaaatcagg tttggattgc
    23221 tggaggtatt gggatcaccc ccttcatctc ttacatccgt gaacatccta ttttagataa
    23281 acaggttcac ttctactata acttccgtgg agatgaaaat gcagtctacc tagatttact
    23341 ccgtaactat gctcagaaaa atcctaattt tgaactccat ctaatcgaca gtacgaaaga
    23401 cggctatctt aattttgaac aaaaagaagt gcccgaacat gcaaccgtct atatgtgtgg
    23461 tcctatttct atgatgaagg cacttgccaa acagattaag aaacaaaatc caaaaacaga
    23521 gcttatttac gaaggattca agttcaaata agtactcata ctctcctggg aattctagga
    23581 gagtttttta tagccaaatg aaataagtcc ggaacgatgg aattttggca ttcaaatcaa
    23641 ttgataagaa tgttttatag tggagtgaaa taggatacga acaaattgat taggaaaatc
    23701 aaatgaattt atagaaatct tttagcagtt atgttgtcct attctcgttt caaaacgcta
    23761 tagaagcagc attgtactag tctagattca gtttactata ctaaaacgag tagcttgaaa
    23821 tcaaaaaacc caccctcaca ggcaggtttt atctgtatta ttcagctaga ttatgcttta
    23881 ccttctgaac cgaatacgtc gatacgttct tcaaccgatg cttggatagc ttttacaccg
    23941 tcagccaaga attttcgtgg gtcgaagagt tttttcttgt cgtattctgc ttcgtttgct
    24001 tcgtagtcac gagcaaattt acgagttgcg ttagcgaatg cgatttggca ttctgtgtta
    24061 acgttaactt tggcaacacc aagtttgata gctgcttgga tttgctcatc aggaatacct
    24121 gatccaccgt gcaatacgat tgggaatcct ggaagagctt ctgtcaattt ttgcaagtgg
    24181 tcaaggtcaa gaccttccca gtttactggg taagggccgt ggatgttacc gataccagct
    24241 gccaagaagt cgataccagt ttcaaccatt gctttagcgt cttcgattgg agccaattca
    24301 cctttaccga tgattccgtc ttcttcacca ccgatagtac caacttcagc ttctactgag
    24361 atacctttag cgtgtgcttt ttcaacaact tctttagcca atttaaggtt ttcttcaact
    24421 ggaaggtgtg aaccgtcaaa catgattgaa gtataaccaa cttcgataca ctcaagtgca
    24481 tcttcgtagt gaccgtggtc aaggtggata gctaccggta cagtgatacc cattgattca
    24541 acaaggttag cgatcaagtt gcgagcaact ttataaccac ccatgtattt agcagcaccc
    24601 attgaagttt ggatcaaaac tggagctttt ttagcttctg ctgcgcgcaa gatagcttga
    24661 gtccactcaa ggttgtttgt gttaaatcca ccaactgcat aaccgttgtc acgggctgct
    24721 tggacaaatt tttctgctga aacgattgcc attttatcag gcctcctgta tatttttatg
    24781 ggtcatccca tttacattgt tcattttatc actttttgcc aaaaaaatct agtttttccc
    24841 gcagtttcga ttgattttct tctaactcca tctatgtaaa ccctttctct ccctagtctt
    24901 gggcgacttt tggaaaagct ataaagaagg ttaaacgatt ctcctccatc tcgaaacgat
    24961 aagctaattt ttcatgttct aatagactct taaccacaaa gagccccata ccagacccct
    25021 tgaccttgcg actagcattg ccagaaaaaa actgggctag tttttcttgt tcctctgagc
    25081 tacagctatt ttcgataaaa agttctcctt ctctttctcc aattcgaact aagccacctg
    25141 gaacagagtg cttaatggca ttgctgatga gattagaaag aatcaacttc ataactgatg
    25201 ggtttagata agcctgctga tgggtcaaac tattgtctat ctggagctct ctttccttgg
    25261 ctagcaaggc ataatctttg accagatttt tcgtcatctg gaggaggtca attgtttccc
    25321 tatcatctcg caattcctgc acagaagaga gggaaagtat ctgcagaaca tggtgattga
    25381 gttcatccac aatccccaag gcaactccca gatactggtc tctatcctta taacgaccga
    25441 tattctctct catattttcg attaggattt tcaaactagc cagcggtgtt ttcaattcat
    25501 gagaagctcc tcgtaggaat tcgaccttca tcttctccag ctggagaatg gcttcattct
    25561 tttcatgcaa gtccgcaata acagtcaaga gatgctggta gaggctattg atttgttcct
    25621 tgagattacc tatctcatcc ttagaatcca cgcgcaatcg cacttgggaa tccaggtcca
    25681 tcatccgacg ggtcacccgc ttgatttcca aaatcggtgc aacaatagtc cgagcgtaga
    25741 tgtaggccac caagagggaa atcagaaagg aggccagcaa ggtataggga agaaactgga
    25801 gactgatttg ctccgcttcc ttttgtaaat ccatggaagc tagaaactgg agaatcatag
    25861 taccaccgtc ttgcgttttc acctcgcgct cctcaataaa gagagaggtt gtctggcggt
    25921 ctgtgtccag aggaagactg tccttgactt ctaacttgtc ctcggtcatc tcacctttga
    25981 cggtcccctt gatatcacta gtctgggaat acaagtctaa cacttgctcg atactctgcc
    26041 tatctttccc ttctagggac tgggcaatgg ctgttgcctt ttgaccaatg gtttcctgac
    26101 gatgactcag ataagtcgaa ggaaaaagaa aataaatagc taaatgaagg cagataacca
    26161 gaacactaaa tatcgagaaa gtatatataa atatctttgt aaataaacct gttcgtttca
    26221 ttttcgctcc aatttataac caacattgcg cacagtgagg atacaatcca agtctagctt
    26281 tttccgcaat tccttgatat aaacatcaat aacacggtca aagggaacct catctgtcgc
    26341 tttccagacg gcatcgataa tctgagaccg agtcaaggcc cggccttcat ttttcactag
    26401 atagtccaga atttccaact ctttggcatt gataggcact tcttgacctg cgaggcttgc
    26461 actgtagctt tcaaagtcca ccttggtatc cttgtaagaa aagattcgtc ctgtatcgta
    26521 gtagcgcttg aaaatcgcgt ccaccctcac ttttaagagg gagagggaga aaggtttttc
    26581 cagatagcca tctgccaaag aggcaaaggc actcatcttg tattcctcat cctgaaaagc
    26641 tgtcaacatc aagacaggaa cctgactggt tttacgaatc tcagctagga cttctaggcc
    26701 gttaagcttg ggcatctgga tatccagtaa aaccagggcc acctcatagc tagaaaattg
    26761 ctccagagct tcctgaccgt ccgctgcctc aatagtttca tagccacaat ccgtcaaata
    26821 atcactgacc ccctcacgga tcatctcttc atcttctaca attaaaattt tcatacttta
    26881 actgctctct attttttatt tttcttagaa taaataccta ctctattttc tattatagtc
    26941 tcttgctggc cttttgtctg taagcaactg accactagat aaaacgttgt gaaattcctt
    27001 tctcataaat ttcatatatt tagtatatta tatttaagca ctaaagtaca aagaaaacaa
    27061 ctgaaagcaa tgattttcac cactgctttc tgcttcattt atcattttaa aactttcagt
    27121 tgctagcctc atttttcact ctggcatcgg tattattcac catccagcaa gagttctttt
    27181 ggttgttttc taaggagatt acttgaagca agcgccataa cggccaccac tagaaccaag
    27241 gcaaggacaa agacgatgat aaaatctgat gtctgaatag aaatgtctag gctcgataag
    27301 gtcttactaa agccatctac ttctgcaccg ccaccaaggt tagaggcttg aaccgcctta
    27361 ctagcctgtt tggcaacacc tgaagtcaca ttggcaagga cagtgtttcc aattgcacgg
    27421 gcagtgtaat tagctaggaa gtaagcagaa actagagcag ggatagcaat caagatagat
    27481 tcggtgatga attgacccaa gatacttgcc tgcttgaggc cgatagagag gagaattccc
    27541 acttccttgc gacgggcgtt gatccaaagg ctgagcaaga gggcaaggag gagaactgag
    27601 aagctcaagc taccccagaa gaggaggttg gccatcttgt acataccaga gatagattgc
    27661 tcaagagctg ggtagttaga ggagctcttg acaagtgtgt agctcttcca gttgatacca
    27721 ctgatgccat tcaactcttt cataacatca tccaagttct tgtctgctgt tacaaagaag
    27781 gttgcgtccc cataaatggc tgtgtcttct gtgtatccat aaagttttgc agcagtgtca
    27841 atgtctgtaa tagctgtgtt ttcgtaaagt tcttgtgagt aggttactgc tgacttatta
    27901 tgaccatcaa agagtccctt gattgtcact tcaactgttt ccttggctcc tttttcatta
    27961 tctgcatcgt agatattaga gtccagttta accttgtccc ctactttcca gccgtgtttg
    28021 gctgccaagt ccttgtgcaa gaggatttta tccttgtcgt cgttggttaa gtgctctcct
    28081 tcgactagtt tataagaacc agagacaaac ttgtcttctt taaaggagtc attgacacct
    28141 gtaatcatca agctacttcc aaaacgtttg gcacgatcag cagtgagatt cttcttggtt
    28201 tctggcgttt caatcaggtc atatccagtc aaatctccga tagcgttgat acgtttgaca
    28261 taagactcga tggccttgtt ttcggtgatt tttttgatgt cttcaccctt gatattccca
    28321 gcaccacgag gcgttccttg gttgacgcga cgattgattt gcatggagaa gctattggtg
    28381 atatttttaa aggtctcctg agaagccttg gcagtagctc ccttgattga caagccgacc
    28441 aaactcaagc tcgccatgag gagaataatc aggaagatga caatcgattt aaaaaacttc
    28501 cttgtaacat aggcaaatgc gttgtgtaac atagattccc tttctagatt ttgttttaat
    28561 cattctatca aaataagctc aaattattta ctagtattgc gcgtttcagt cagtttctta
    28621 tcctttaatt caagtgtaat atctgacgct tgtgccactt ctttactgtg agttacgaca
    28681 atcacacatt tacctgtttt ctgggcaagt gatttgagca gttcgacaat atctccagca
    28741 gttttaggat ccagatttcc tgttggctca tcagcgagaa taactggagc ttctgatact
    28801 aaactacgag caatggcaac acgttgttgt tgaccacctg acaactggag aacattccgc
    28861 ttgatctgac tttcatccaa accaagctca agaagtgtat ccttgctggc ctttttgtta
    28921 accaagcgga tattttccag tggagaaaga taatctatca agttataatt ttgaaagacc
    28981 aaggaaatat ggtgcatgcg atggtaagaa tagcccttct tacgaatatc ctctccttga
    29041 aaaaggatag aaccttcaac aggactatct agaccagcaa gtagggacaa gagagtggat
    29101 tttcctgctc ctgactcccc aataatactg taaaatttcc cgggttcaaa attataattg
    29161 atctgatata ggactgcttc agcagtgttc ttataacggt aggtaaggtc ttgtaattgt
    29221 aataaagtca tgatttctcc ttcttatact caatgaaaat caaagttcaa actaggaagc
    29281 tagctgcagg ttgctcaaag cacagctttg aggttgcaga tacagctaac gcggtttgaa
    29341 gagattttcg aagagtatta actaatagat gataaaattt ctttaggcga ttttctaaat
    29401 aagaatagga aacaaagtgc tacagacaag caactaagca gaactagaaa gacataggat
    29461 tctgcaaatg ataggatatt agttgataga ctgcttgctt tagctagcgt gtcttgtaag
    29521 cttgcctgct ctccacttgc tagtagagtt tggagtaggt aagatgtgat tgcgtttcct
    29581 acaacaaatg ctggaagcaa agcgccgaga gataccaaaa ctacctctaa acagaattgt
    29641 aggaagattg aggtcttgcc ttttccaagt gccagtaaaa tccccacttc gtagaccctt
    29701 tctctcaacc agagagacaa aacaagaatt aaggcccctg ctcctgctat caacatccca
    29761 taaaggaaga tggtcagaaa ggtttggaag gttgcaactg agtctttgat ttgttcaaaa
    29821 gccttgtttt ccttttcgac ttggtagcct tgattttcca aggccaagtt ttctacctgc
    29881 ttcacgagtc cgtccatttc cttaggattt tctacataga agcgcgctgc actgacttgc
    29941 ggttcactat ttcccaaaag agtttggcta ctgtcatagt ctgtaaagac ttgattttca
    30001 ctgaagtcag aagacaagcc tgtgaatttc tcctgttttt taccagaaaa gatgccgaca
    30061 atttcaaact caactgtttg tcctttacca gcttcggact gaccagcatc taaggcaatc
    30121 ttgccatgaa gcgaaagacc attcttctta gccaactctt cgtggatgag aattttcttt
    30181 gaatcccctt tttgaagatg tctcccttct tttagattga aagccgaact ggtaaaggtc
    30241 acatccttgg atgaatcctc cagagctgtt aagctaacca agttcttgtc cgcagctgac
    30301 aaatcatcac gttcaacgct ctgctcgcca ctcactgctt ccttgtcttt tagttttgcg
    30361 accgtctcca gttcaggaga aacattttcc agtcccttaa tcttgcttac agatgctagg
    30421 tctgacaact tgaatgtctg accattttct atcttcttaa ttgaaaaaga ggtattgagt
    30481 gatttgtaaa gattggtttc cactgttttg ttggacttca tcagagtcaa acaggctgag
    30541 attccggcca ataggaccaa taaaatcaga aataaaataa aacttctcag tcgttttctg
    30601 ctgacataag cccaagatct ttggattgga ttcatttgtc acctccatat ttgtaagact
    30661 attataaaac ccaaatatga aatgtttatg aaatacgaaa aaaaaaatat caaaaagagc
    30721 aacggctttc accgttgctc tttcaatcac tattctagct agtttccgac tagtttaagc
    30781 ttgacttatc ttaactgagc cagaatagct ttgagtttct caatcaactc atcttctgtg
    30841 tgatcagact ctttctcatt ggctaggaaa ggaactgctt gagcgagagc ttctcgtgct
    30901 tggtcgagga gtttcgaatc tacacttgta aggtcgcttt cttgcagaac cttagtcaat
    30961 cccttggtca atttcttgag ttctgactct ttcttacgac gcgcgatgag gaagagaagg
    31021 agaccaagaa aggcaagcag gctagcaatc atcgtaccat atggaagatg accttgctct
    31081 ttgcttgttt cttgcatttc ctcttcatcc ttagtcgctt gcttgccttt caaggattcg
    31141 agtgcttctt tgaccttagc agtaatctct ctcaagcctg cctctgtcaa gtcagtattt
    31201 ctaagggcta cttgactctc tacgagaatg atcttagcag catcgatgac agattgatca
    31261 ataccatcca agtttttcaa gcgagtttcc aattcttcaa ccaatcgagc aagttcaaac
    31321 ttgtcaacag gacgagcctc actaggagtt gctgtattgc ttgaattatt tggagtgctt
    31381 ggagaaactg gtgtttcttg agctggagta cttgcttgag cctgtcctcc aacagtagac
    31441 gatggagtag cagaggtcgt gttcctacta tcgtcggtcg tcacattagg cgctggagtg
    31501 ttggcactgt tatctggtgt cacactgtta ctattgctat cagcaggggt ggtagtacca
    31561 ccgttgttgg tgttagcact attgttagtg ttgccactgt tgccatcctt acttggtaca
    31621 gaagttggct tatctac
//
LOCUS       DAVDZK010000026        31457 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVDZK010000026 DAVDZK010000000
VERSION     DAVDZK010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.027"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            161..2416
                     /locus_tag="VUX16_001381"
     CDS             161..2416
                     /locus_tag="VUX16_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET8124334.1"
                     /translation="MLGAGIALGYGVALFDKVRVPQTEELVNQVKDISSISEITYSDG
                     TVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAVIRATLGKFVGL
                     GSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEILTTYLNVAPFG
                     RNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPYENTGELKSDED
                     LEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGISRDYLYFTTLA
                     EAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITTTIDQKIHSAMQ
                     SAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNHAFDTKRSPAST
                     TKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMTLGEALNYSWNI
                     PAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQHTNGYQTLANN
                     GVYYQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVLSSRVTTTFKSN
                     LTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNHSLSRRAGYSNN
                     SNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVSVEGKEVEVTGS
                     TVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSSSSSSSSDSSNS
                     STTRPSSRARR"
     gene            2481..3392
                     /locus_tag="VUX16_001382"
     CDS             2481..3392
                     /locus_tag="VUX16_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET8124335.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            3622..4320
                     /gene="dapD"
                     /locus_tag="VUX16_001383"
     CDS             3622..4320
                     /gene="dapD"
                     /locus_tag="VUX16_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET8124336.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            4388..5518
                     /locus_tag="VUX16_001384"
     CDS             4388..5518
                     /locus_tag="VUX16_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET8124337.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVDAVSSFLKKKAAE"
     gene            5530..6069
                     /locus_tag="VUX16_001385"
     CDS             5530..6069
                     /locus_tag="VUX16_001385"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET8124338.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            6053..6730
                     /locus_tag="VUX16_001386"
     CDS             6053..6730
                     /locus_tag="VUX16_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET8124339.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIILRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(6797..7696)
                     /gene="galU"
                     /locus_tag="VUX16_001387"
     CDS             complement(6797..7696)
                     /gene="galU"
                     /locus_tag="VUX16_001387"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET8124340.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(7718..8734)
                     /locus_tag="VUX16_001388"
     CDS             complement(7718..8734)
                     /locus_tag="VUX16_001388"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET8124341.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            8946..9385
                     /locus_tag="VUX16_001389"
                     /pseudo
     CDS             8946..9385
                     /locus_tag="VUX16_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(9500..9925)
                     /locus_tag="VUX16_001390"
     CDS             complement(9500..9925)
                     /locus_tag="VUX16_001390"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET8124342.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(9993..10643)
                     /gene="phoU"
                     /locus_tag="VUX16_001391"
     CDS             complement(9993..10643)
                     /gene="phoU"
                     /locus_tag="VUX16_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET8124343.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELACARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(10658..11410)
                     /gene="pstB"
                     /locus_tag="VUX16_001392"
     CDS             complement(10658..11410)
                     /gene="pstB"
                     /locus_tag="VUX16_001392"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET8124344.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(11412..12227)
                     /gene="pstA"
                     /locus_tag="VUX16_001393"
     CDS             complement(11412..12227)
                     /gene="pstA"
                     /locus_tag="VUX16_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET8124345.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLVIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(12220..13083)
                     /gene="pstC"
                     /locus_tag="VUX16_001394"
     CDS             complement(12220..13083)
                     /gene="pstC"
                     /locus_tag="VUX16_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET8124346.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(13201..14076)
                     /locus_tag="VUX16_001395"
     CDS             complement(13201..14076)
                     /locus_tag="VUX16_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HET8124347.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGKYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(14243..15574)
                     /locus_tag="VUX16_001396"
     CDS             complement(14243..15574)
                     /locus_tag="VUX16_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET8124348.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(15575..16282)
                     /locus_tag="VUX16_001397"
     CDS             complement(15575..16282)
                     /locus_tag="VUX16_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET8124349.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(16366..16668)
                     /locus_tag="VUX16_001398"
     CDS             complement(16366..16668)
                     /locus_tag="VUX16_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET8124350.1"
                     /translation="MTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(16655..16876)
                     /locus_tag="VUX16_001399"
     CDS             complement(16655..16876)
                     /locus_tag="VUX16_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET8124351.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            16838..17396
                     /locus_tag="VUX16_001400"
                     /pseudo
     CDS             16838..17396
                     /locus_tag="VUX16_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(17786..19477)
                     /locus_tag="VUX16_001401"
     CDS             complement(17786..19477)
                     /locus_tag="VUX16_001401"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET8124352.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILNLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIATELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKAQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            19613..20059
                     /gene="argR"
                     /locus_tag="VUX16_001402"
     CDS             19613..20059
                     /gene="argR"
                     /locus_tag="VUX16_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET8124353.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLANETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            20110..22644
                     /gene="mutS"
                     /locus_tag="VUX16_001403"
     CDS             20110..22644
                     /gene="mutS"
                     /locus_tag="VUX16_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET8124354.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSCQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIREILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREESA
                     NLEYEIFMRIREEVGKYIQRLQSLAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IQKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAETAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIESGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            22791..24485
                     /gene="patA"
                     /locus_tag="VUX16_001404"
     CDS             22791..24485
                     /gene="patA"
                     /locus_tag="VUX16_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET8124355.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNFYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQTIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAVKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(24814..25077)
                     /locus_tag="VUX16_001405"
                     /pseudo
     CDS             complement(24814..25077)
                     /locus_tag="VUX16_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            25274..27040
                     /gene="patB"
                     /locus_tag="VUX16_001406"
     CDS             25274..27040
                     /gene="patB"
                     /locus_tag="VUX16_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET8124356.1"
                     /translation="MKTVQFFWNYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNVVLYIGLILV
                     MFSRNVTLALITIASTPLAFFMLIFIVKMARKSTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLVNTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            27179..27868
                     /locus_tag="VUX16_001407"
     CDS             27179..27868
                     /locus_tag="VUX16_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET8124357.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPLGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            27872..28051
                     /locus_tag="VUX16_001408"
                     /pseudo
     CDS             27872..28051
                     /locus_tag="VUX16_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            28038..29387
                     /locus_tag="VUX16_001409"
     CDS             28038..29387
                     /locus_tag="VUX16_001409"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET8124358.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLIVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANSWVTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKSLMEGANTARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            29511..30971
                     /locus_tag="VUX16_001410"
     CDS             29511..30971
                     /locus_tag="VUX16_001410"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET8124359.1"
                     /translation="MLKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGVTPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     TDLETIFQMAKPFLEEAGCLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            30985..31419
                     /locus_tag="VUX16_001411"
     CDS             30985..31419
                     /locus_tag="VUX16_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET8124360.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAIPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         9156 a         6153 c         6906 g         9242 t
ORIGIN      
        1 ccagcaaaaa caaaaaaata aaaaatcagc tagacctggc aagaaaggtt caagtaccaa
       61 aaaatctaaa accttagata agtcagccat tttcccagct attttactga gtataaaagc
      121 cttatttaac ttactctttg tactcggttt tctaggagga atgttgggag ctgggattgc
      181 tttggggtac ggagtggcct tatttgacaa ggttcgggtg cctcagacag aagaattggt
      241 gaatcaggtc aaggacatct cttctatttc agagattacc tattcggacg ggacggtgat
      301 tgcttccata gagagtgatt tgttgcgcac ttctatctca tctgagcaaa tttcggaaaa
      361 tctgaagaag gctatcattg cgacagaaga tgaacacttt aaagaacata agggtgtagt
      421 acccaaggcg gtgattcgtg cgaccttggg gaaatttgta ggtttgggtt cctctagtgg
      481 gggttcaacc ttgacccagc aactaattaa acagcaggtg gttggggatg cgccgacctt
      541 ggctcgtaag gcggcagaga ttgtggatgc tcttgccttg gaacgcgcca tgaataaaga
      601 tgagatttta acgacctatc tcaatgtggc tccctttggc cgaaataata agggacagaa
      661 tattgcaggg gctcggcaag cagctgaggg aattttcggt gtagatgcca gtcagttgac
      721 tgttcctcaa gcagcatttt tagcaggact tccacagagt cccattactt actctcctta
      781 tgaaaatact ggggagttga agagtgatga agacctagaa attggcttaa gacgggctaa
      841 ggcagttctt tacagtatgt atcgtacagg tgcattaagc aaagacgagt attctcagta
      901 caaggattat gaccttaaac aggacttttt accatcgggc acggttacag gaatttcacg
      961 agactattta tactttacaa ctttggcaga agctcaagaa cgtatgtatg actatctagc
     1021 tcagagagac aatgtctccg ctaaggagtt gaaaaatgag gcaactcaga agttttatcg
     1081 agatttggca gccaaggaaa ttgaaaatgg tggttataag attactacta ccatagatca
     1141 gaaaattcat tctgccatgc aaagtgcggt tgctgattat ggctatcttt tagacgatgg
     1201 aacaggtcgt gtagaagtag ggaatgtctt gatggacaac caaacaggtg ctattctagg
     1261 ctttgtaggt ggtcgtaatt atcaagaaaa tcaaaataat catgcctttg ataccaaacg
     1321 ttcgccagct tctactacca agcccttgct ggcctacggt attgctattg accagggctt
     1381 gatgggaagt gaaacgattc tatctaacta tccaacaaac tttgctaatg gcaatccgat
     1441 tatgtatgct aatagcaagg gaacaggaat gatgaccttg ggagaagctc tgaactattc
     1501 atggaatatc cctgcttact ggacctatcg tatgctccgt gaaaagggtg ttgatgtcaa
     1561 gggttatatg gaaaagatgg gttacgagat tcctgagtac ggtattgaga gcttgccaat
     1621 gggtggtggt attgaagtca cagttgccca gcataccaat ggctatcaga ccttagctaa
     1681 taatggagtt tattatcaga agcatgtgat ttcaaagatt gaagcagcag atggtagagt
     1741 ggtgtatgag tatcaggata aaccggttca agtctattca aaagctactg cgacgattat
     1801 gcagggattg ctacgagaag ttctatcctc tcgtgtgaca acaaccttca agtctaacct
     1861 gacttcttta aatcctactc tggctaatgc agattggatt gggaagactg gtacaaccaa
     1921 ccaagacgaa aatatgtggc tcatgctttc gacacctaga ttaaccctag gtggctggat
     1981 tgggcatgat gataatcatt cattgtcacg tagagcaggt tattctaata actctaatta
     2041 catggctcat ctagtaaatg cgattcagca agcttcccca agcatttggg ggaacgagcg
     2101 ctttgcttta gatcctagtg tagtgaaatc ggaagtcttg aaatcaacag gtcaaaaacc
     2161 agggaaggtt tctgttgaag gaaaagaagt agaggtcaca ggttcgactg ttaccagcta
     2221 ttgggctaat aagtcaggag cgccagcgac aagttatcgc tttgctattg gtggaagtga
     2281 tgcggattat cagaatgctt ggtctagtat tgtggggagt ctaccaactc catccagctc
     2341 cagcagttca agtagtagtt ctagcgatag cagtaactca agtactacac gaccttcttc
     2401 aagggcgaga cgataattct ctaaatgaag tggccaatca atggattgcc acttttttcc
     2461 tttcgtgtta caataagggt atgaatcagt atcagaaaaa gattgttaac ggaaaaattt
     2521 attcgctcct atccggctta atatggggaa tctgtggaat tttaggagag tacttcttta
     2581 ctcattatca ggtgtcttcg ggctggatta cctctatgcg tttgacactg gcagggagtc
     2641 ttgtactcat ttggtctgca atacaattaa aatcgcaagt gctagatatt tggcgagaca
     2701 agaaaaatta cctgcccttt ttagcctatg ctattttggg gattttttca gttcagtatt
     2761 ttttctatct ctgtgtagaa tactcaaatg ctacgacagc aactatttta cagtttatta
     2821 gccctgtctt tatcctcttt tataatcgct tggtttatca aaaacgagcg tcaaaaagcg
     2881 ctgttttcta tgttttggtt gccatgctgg gtgtttgctt gatggcgaca aagggagatc
     2941 tctctcagtt atccatgacg ccgctagctc ttataacagg tttgctgagt gccatgggtg
     3001 ttatgtttaa tgttatcttg ccccaacctt ttgctaagcg ttatggtttt gttcctacgg
     3061 ttgggtgggg gatgattttg gcaggtttgt ttagcaatgt cctctcgccg gtttatcagc
     3121 tttcctttac tcttgatatt tggagtatct tgatttgcct cattatcgct ttctttggaa
     3181 cggcttttgc ttttttcatt tccatgaagg ctgtgtcctt ggtttctcct ttggtggttt
     3241 ccgttatcag tgccagtgaa cctctctctt ctgctctctt gagtgttttg ttcttaggat
     3301 tagtagtgga ttggtccctc cttctagcta tagccttgat tattttaccc atgatatttt
     3361 tgtctataga agaagcgaaa gaaagtagat aaaaagtctt ttcttaattc taaaagtgtg
     3421 ctatactaga atagtcaata aaacacgggg agatagttgt gaagagtgtt tttaggttgt
     3481 atcggtaggg gcttgctttt accgacagca cgttttatct cacaacccta aaaaatcata
     3541 cctaaaaaca gacaaaaagg tttcaaattt gaggcctttt ttggtagaat aggtatcatt
     3601 ataacgaacc aggaggcacc tatgactgct acaaaaatga acgctcaaga aattatccaa
     3661 tttatcgcca atgctgaaaa gaaaaccagt gtcaaagtaa cctttgaggg gcaactcgca
     3721 actgctgtgc ctagctctgt tgtcaaacta ggaaatgtcc tattcggaga ctggaaggac
     3781 gtggctccgc ttcttgaagg tttggtagaa aatcaagatt atgttgtcga gcaagatgct
     3841 cgtaattctg cagttccttt gctagataag cgtgctatca acgctcgtat cgagccaggt
     3901 gctattatcc gtgaccaggt ggaaattggt gacaatgctg ttatcatgat gggagctgtt
     3961 atcaatatcg gtgctgaaat cggtgctgga accatgattg acatgggtgc catccttggt
     4021 ggccgtgcca tcgttggaaa aaatagccac gttggtgcag gtgcagtttt ggcaggtgtg
     4081 attgagccag ctagtgctga accagtccgt gtcggagaca atgttcttat cggtgctaat
     4141 gcagtggtta tcgaaggagt ccaaatcggt agtggttcag ttgtcgcagc aggagctatt
     4201 gttacccaag atgtcccaga aaacgtggta gtagcaggtg ttccagctcg tattatcaaa
     4261 gaaattgatg cccaaactca acaaaaaaca gcgctagagg atgcgcttcg taccttgtaa
     4321 ttgtaaaagt aaaaaagagg cggaaccctt tttccagcct ctttctgcta tatcggagga
     4381 cagatagatg ttagatttga ttcagactag acgagattta caccagatac cagagattgg
     4441 cttggaggag ttcaagactc aggcttattt gctggatgtg attgagaaat tgactacggg
     4501 caaggatttt gttcaaattc gtacttggcg gacagggatt ttggtctacc tgcagggaag
     4561 tcagccggag cgaaccattg gttggcggac agatattgat ggcctgccta tcgtcgaaca
     4621 aacaggtcta ccttttgctt ctcaacacca aggtcgcatg catgcctgtg gtcatgattt
     4681 tcatatgacc attgccttag gctgtcttga gcgcgccctt gaggagcaac ccaagaataa
     4741 tctgctcttt ctatttcagc ctgctgaaga aaatgaagct ggtggtatgc tcatgtatga
     4801 ggacggtgct tttggagatt ggttgccaaa ccaattctat ggtctccatg ttcgtccaga
     4861 tttgaaagtc ggccagattg cgactaatac tcatacactc tttgcaggaa cttgcgaggt
     4921 gaagatccgt ttcaaaggca aaggtggcca cgcagctttt cctcatgaag ccaatgacgc
     4981 cttggtggcg gctagttact ttgtgaccca agtgcagtca gttgttagcc gcaatgtcaa
     5041 cccaatcgag ggagcagtgg tgaccttcgg cgtttttcaa gctggaacca ccaacaatgt
     5101 catcacagac acagcttttt tacatggaac tattcgtgcc ttgacacagg acatgagtct
     5161 cttggtgcaa aagagggtaa aaacagttgc agaaggggtt gcagctgcct ttgatatgga
     5221 agtcgaagtg gaactcaaac aaggtggata cctacctgtt gagaacaatc cagccttggc
     5281 gcgtgaactg atggacttct ttgacgaaaa agacggaatc gagttgattg atatcgaacc
     5341 tgctatgaca ggcgaggact ttggttatct cctttcaaag gttgatggcg tgatgttttg
     5401 gctaggtatc gatagtccct acgctcttca tcaccctcaa atgagtccta aggaagaagt
     5461 cttagctatt ggggttgatg cagtctctag tttcctgaaa aagaaggcag cagaatagag
     5521 ggcttgtata tgaaatcgga attacgcaag caagtcttgc atgaaatgaa ggctttatct
     5581 caagaacaaa aacaggctat agaccaagct ttaaccgagc gaattttaca acaccccttt
     5641 tatcaagaag ccaaggtcat cgcaacctac ctctcttttt ctcatgagtt tcaaacgcgg
     5701 gaactgattg agcaggcgct gaaggacggc aagaaggttt taatacccaa aacttatccc
     5761 aaggggcgca tggactttgt agtctatgat ccgcagcagt tggtaaaaac tgcctttgcc
     5821 ttactggagc cacagggaga tttggaagtg gtggatgtat ctcagattga tttgattcat
     5881 gttcctggcc tggcttttac gacggatgga tatcggattg gatatggtgg aggttattat
     5941 gaccgctatc tggaacattt ttctggtcat actttgagta cggttcatcc ttgtcaaatt
     6001 caggacttta tacctgaaaa ccatgatatt cctgttcagg aggtattaat tgatgaagga
     6061 aatctttgat agacgttacc ctgtgacgag tttcttcctc ttagtgacgg ccttggtatt
     6121 tttactaatg ttggtcactg caggcggaaa ctttgacagg gcagatacat tatttcgatt
     6181 tggagccatg tatgggccag ctattcgcct ctttcccgag caggtttggc gtctcttgtc
     6241 tgccattttt gttcatattg ggtgggaaca tttcattgtt aatatgcttt cactttatta
     6301 tcttggaagg caggtagagg agattttcgg ctctaagcag ttcttttttc tctatctctt
     6361 atcaggaatg atgggcaatc tctttgtttt tgtatttagt cctaaatcct tagcagcagg
     6421 cgcctctacc tctctttatg ggctatttgc cgcgattatc attcttcgct atgcaactcg
     6481 caatccttat atccaacagc tagggcaatc ctatctgaca ctttttgtgg ttaacattat
     6541 tggaagtgtt ctgattccag gaatcagcct agcaggccat atcggtggtg cagttggtgg
     6601 cgcatttcta gcagttatct ttccagttag aggagaaaaa cggatgtata acaccagcca
     6661 gagattagga gcggtagtct tgttcgtagg actcgccatt ttgcttttct acaagggaat
     6721 gggaatgtga cgaagttgaa agaaaatttg tgtaatgaaa aaagataagg cattttttga
     6781 accttatctt tttattttat tccttctcag tcaattcttt tccaagttgg atgaggtaat
     6841 tcttcaaatc atctttgact tgtggatgtt tgagggcgta gtcaatagat gttttcataa
     6901 agccaaactt atccccaacg tcgtaacgag ctcctgtaaa ttcacgggca aaaacacgct
     6961 gtgttttatt aagagtatcg attgcatcag taagttggat ttcatttcca gcaccaggag
     7021 cttggttttc gaggatttgg aaaatttcag gcgtgaggag gtagcgtccg ataatagcaa
     7081 ggtcgctagg agcgtcctct ggagctggtt tttcaacaaa ggtttcaaca ctgtaaagac
     7141 catcttttcc ttcgccttgc ggagcaataa ccccgtaagc agatacttcg tcatgaggga
     7201 ctggcatgac agcgatagta gacgcgtggg tacgcttgta gtcatccatg agttgtttgg
     7261 taagtggaac agccttttcg tctgtgatat ccatcaagtc atcaccaagc ataacgacaa
     7321 aaggttcatt tccgacgaaa gccttggctt gcaaaacagc atctccgaga ccgcgtggat
     7381 gagtttggcg gataaaatgc agacgcatgc cagttgtttc atcaactagc ttcaaaagat
     7441 ctgttttccc tttttctttg aggttatatt ccaattcgaa gtttgaatcg aagtggtcct
     7501 caatagaacg ttttgattta ccagtgacaa ctagaatatc ttcaatacct gatttgagag
     7561 cctcttccac gataaactgg atagttggtt tgtctacgat tggcaacatt tctttggcaa
     7621 gggccttggt tgctggtaaa aatcgagttc ctagtccagc agcagggata actgcctttc
     7681 taacttttga tgtcataaaa atcctttcta tagagggtta agaccactca ttttctgctt
     7741 taaattcatt gttcatgatg tcataaatgg catctttgat attggttccg tgataaataa
     7801 cttggtaaat agcctgtgta atgggcatat agactccaag ttcttgggct agttcatagg
     7861 ctgctcgagt cgttgaaatt ccttcgatta ccatgcccat attagcttct atatcagcta
     7921 gggattctcc tcgtccgaga gcatctccag ctctccagtt acgagagtgg atggaagttc
     7981 ccgttacgat caaatctccc acaccagata agccgctata ggtcagtgga ctggccccga
     8041 gtgctacccc taggcgggtg atttctgcta aacctcgagc gatgatggct gccttagcat
     8101 tatcaccaaa tccaagacca tgtaaagctc cagcaccgac agcaataata tttttaagag
     8161 caccagcagt ttcaaccccg ataacatccg tattggtata aagtcggaag tagtgattac
     8221 taaatagctt ctgaacgtat tgagctgttt gtaaatcttt agaagcagca gttattaaag
     8281 ttaggtcacg cacaatggtc tcttctgcat gactaggccc tgaaacaacg acgatatcac
     8341 tacggagatg ttcaggaatt tcttcttcaa gaatggttga taatcgttta tggctatcag
     8401 gttctaatcc ctttgatgcg tgcatgatga taaccttatg gtccaaggtt tgtgcaactt
     8461 gctgggcaac aagtcgtgtc acttttgttg ggacaacaaa caaaatcgca tccacatctt
     8521 tcaatgtttc tgctaagtcg gtgtaggcaa tgatattttc gtctagaacg acatctttaa
     8581 agtagtgctt attagtatgg tgtgtattaa tttcattgat ttgctcggga agatttcccc
     8641 aaatacgtac ctcgtgtcca ttgtcattta agacttgtga aagggcggtt ccccaagaac
     8701 caggccccaa gacggcgacg gtttgttttt ccatgatttc ctccttgata gagttctttc
     8761 tcttattcta tcatattcta gaggattttg cacttgcatt actggggtat ggtggaaaaa
     8821 tacacaaaaa ccgagacgaa gggataaact cttagtcttt agttaaagtg agaagaaatc
     8881 tgatagatag tttgattcag tatatgctta taatagaggt aaacaactca ggaggttctt
     8941 gtaggttgcg agagtttggc gaaaaaatta aaagattacg tttggctaaa aaaatcagtc
     9001 gttcagaatt ttgtggtgat gagtctgaat taagtatccg tcaattaatt agaattgaaa
     9061 atggagaatc cagaccaata ctaacaaagt taaaatatat tgctgaacgt ttgggggttg
     9121 aagattacaa gttgatgcca agttatatag agttggataa ggaataccta gaattgaagt
     9181 atttcttgat gaggattcct acatacgaag atgaaactat cgcccaaaag aaagagagtg
     9241 ttttgataag atttttgaag agtattatga taggttacct gaggaagaaa gatttatcat
     9301 cccaaattat tcatatctgg cactaacgaa ctacacagtt caaaaattac cagaaaagct
     9361 agttgaaata ctgtccttct ggtgattttg cttaatttct gatgttcgag acataattga
     9421 ggagatttgt cttgattttt tcctaaaaaa gggcagactc ctcccttggt ttgatgctcg
     9481 atttttaaaa taaggtgact tattctgtta ggcatgtttt cccctgccct ctagctctat
     9541 atggaacagg gagtatcaga tttatctggc agattgtatc aaataaggct tgaaactgtt
     9601 ttgaataggc gtatagactt gagaatttga gaatatgtcg tctagcagta gagacatatt
     9661 ttccggcaat atgaaggaag agacgtcgaa aacgcttgat agtcaaggcc tttacttcat
     9721 caccagctag ctgctttaaa aagaggtaga gattataagc cagacagccc atcatcatac
     9781 gtacttcatt cttaatcatg gtcgaactat ctgtcttatc cccaaagaat cctgctttcc
     9841 tttctttgat aaagttttca gcattccctc gttcacgata gaattgaaac agctcctcac
     9901 tatctacact gcttaaattg ttcaaatgaa cttttttaca accataaaaa agagcactta
     9961 atcgtactct tctcttttaa ggattagttg aattaattca aatccaccag ttctcctgtt
    10021 tctaggtaga ctaggcgttc acaaatgtta gcaatgtaat cagcgaagcg ttccagatgc
    10081 cctatgatat aaaggtattg agttccattg ggaattgagg tttcttggtc tttcataagt
    10141 ccaatgattt cctttgataa ggcataataa tattggtcaa tctgttcatc tttttgagca
    10201 atactaatag cttttgaggc ttggtgcaaa ggaaaggcaa ccaataaatc ggctagcatg
    10261 ctgagggata atttacccat ttggtgtaac tgttcttcgt caggggctag ttgattttct
    10321 tttagttgca aaacagcttt ggcaatgcct gccatatggt ctcccatacg ttcaaggtct
    10381 gaacaagaag acatgatgct aattacaaat cgaaggtcag acacttgtgg ctgctgcaag
    10441 gctaacaaac gggcacaggc caattcgata gcgctttgac cttggttgat agcatgatcc
    10501 ttattgataa ttagctctgc catctccttg tctttggagg ctaaggccag taaggctttt
    10561 gaagctgttt caaggacaag ttgccctagt cctaaaaagg attgttctaa ttcatgcaat
    10621 tctaagtcaa attgatttct cataggtttt tccttcctta tccgaaccgt cctgaaatat
    10681 agtcttctgt gcgctgatct tttggattgg taaacacgtc aacggtatct ccaaattcgc
    10741 aaatttctcc tgttaagaaa aaagcagttt tatctgaaat acgtgaagct tgttgcatgt
    10801 tatgggtaac aatgataatc gtataatcct tttttagttg ctgaatgagg tcttcaattt
    10861 ttaaagtgga gatagggtct aaggctgaag tcggctcatc cattaacaga atatcaggtt
    10921 ctactgctaa agctcgcgca atgcaaaggc gttgctgctg accgccagat aaggacatgg
    10981 cactcttttt aagatcatct ttgacttctt cccaaatggc tgcccctttt aaagatttct
    11041 ccactaaggc atctaattgt tttttgtctc gaataccatg tgtccttggg ccataagcca
    11101 cgttatcata gatagacatg gcaaagggat taggctgttg aaaaaccatc cctacacgct
    11161 tacgtagctg attaaggttg aatttgctac tataaatatc ttgctcatct aagaggactt
    11221 ggccttcaat atggcaagaa ggaaccaaat cgttcatccg attaagggtt tttagaaaag
    11281 ttgatttacc acaaccagat gggcctatca aggcagtaat ctgtctttct ggtaattgaa
    11341 tcgaaatatt ttttaaggct tgaaaatccc cgtaaaataa gtctaggtgt ctgactgaaa
    11401 atgttcccat actaggaagc tcctttcaca agtttccgag ataataagct tgatagagta
    11461 tttatcatta aaacagtaat aatcaaaatc acaccggtag cataggcttc attgacatgt
    11521 agcccctcac ttgacagcat atacatatgc agggctagag aacgacctga agacatgaga
    11581 ctacttggcg tattggtaga ggtacctaat gtatacatga gggcagctgt ttcaccaacg
    11641 atacggccaa tagctagtat cactccagct aaaatacctg gcatggcaac tggtagaaca
    11701 attctaaaaa cagtccgtaa cttacctgcc ccaagtccat aacttgcttg acgcatgcta
    11761 tcactaacag ataaaagggc ttcttctgtt gagcgaataa tgactggcaa caccatgata
    11821 actgaggtta agattcctga taacagagag tattgaaaac ctaagaagac tacaaagaag
    11881 agcatgccaa acagaccaaa aacaatggaa ggaatcccag ataaggtatc tgaggccaat
    11941 cgcatgattt taacacaaag ggaatctttt tttgtatatt ccacaagata aaaaccagca
    12001 aaaatcccta tgggcaaggc taaaagaaga gcaccaaaga ccagaataac ggtggaaata
    12061 atcgctggca taagggaaat gttctcagaa gtataagtcc aagaaaagag ggatagactt
    12121 agatgaggta agcctttgat gaggataaaa ccaatgacta aaaagagaga gccaaaggtt
    12181 aaagctgaaa aacaataaac gagaagtttt agcaggtatt tactcataag atgattttcc
    12241 tttcaagtag gcaaagtagg cattaatcaa gagaataagg aaaaagagaa ctgctgaggt
    12301 tgcaataagg gcttccctat gctgacctga tgcgtaagcc atttccagaa caatattggt
    12361 tgttaaggtt ctggttcctg aaaagagtcc acttggaata atcggttggt tgcctgctac
    12421 caaaataact gccatggttt cacctactgc gcgaccgatt cctaaaataa ctgctgataa
    12481 aataccagat ctcgcagctg gcaagatgac actaaaaata ctccgttcat gactagctcc
    12541 tagagccaag ctaccagaat aatacgtttt gggaactgtt cggatagcag attctgacaa
    12601 actgataatg gttggcaaaa tcattattcc taatagtaac gaagcggtta ggacactcat
    12661 gccatttcct aaaaagcttc taatccaagg caccaataat tgtaggccga aaaaaccata
    12721 aacaatagat ggaatggccg ccatcaagtt gatagctgat tttaagaagc catagacggg
    12781 ctttggacaa taataaacca taaacaccga tgtcaagatg cctgttggca ccccaatcac
    12841 aatcgctcct aaggtaatta ataaggaacc aacgatcatt ggtaaaatac catagcttgc
    12901 cggaatgttc gttggcgacc aatcactgcc taataaaaaa cgggcaaagc cgtagttagc
    12961 catgaaaggt aagccattac taaaaataaa gaaacagatt agcaaaatag ctacaacagc
    13021 tactgttgca ctcatgaaaa aaattgccct aaaaactgct tctttgaagg cttgttttat
    13081 cacatcttgt cctttctagt gaagaaagta agggagatac gacacctccc tacttgcctt
    13141 ctttatctta ttgtacgatg aaacgtctgc atctctttag agatttatgg agcaaacatt
    13201 ttatttaatc ttgtcccagg tggttaattt gccactaaaa acgtctgcaa gttcagccat
    13261 actgacttgg cttgccttat tgtcattatt gaccacaaca gcaataccgt ctaaagcaat
    13321 agcatcatgg gtgagactct taccttcttc aggagttaat tccctagaaa ccataccaat
    13381 atcagcggtt ttctccttaa cagcggtaat acctgctgaa gacccattag aggtaatatc
    13441 aatcgtaact tctggatttt cttttttata agcttctgct aatttttcca ttaaagaaga
    13501 tactgaagtg gaacctacaa cagacaactt gcctgataag tgttggctgg tatattctgt
    13561 ggtttcggtt ttagcttcaa taaatttatt atctgtgacc acttgttgac cttgtttgga
    13621 gtggataaag ctgataaaat cttgacctag cttggaaaga ttagaagacc aaacaatgtt
    13681 gaagggacgt tgaagagggt atttaccatc taaaactgtg tctcgactag ccttgacacc
    13741 atcaatctct aaagccttga cagatttcgt taaagatccc aaggagatgt agccgatagc
    13801 attagcattc ccttgaactg ctgagagaac accttctgta ctattttgaa tcacagctgt
    13861 tttggcagtg ttgtcaattt ttttatcacc gtcttttttg agaatccctg tgatttctgt
    13921 gaaggcaccc cgtgtcccag agccattttc tcgtgaaatc acctcaatcg ttcctgaagc
    13981 tgactgtttg gaagcagctg actgattgcc acaggcaaca agcccaaatc ctgataagcc
    14041 aatggctgca agagtaagca tttttttgaa tttcataata atcaccttta tctctatgta
    14101 tttttcttgt gtaggcttac tacatttata gtctaacaag tctttgtaaa ggtttatccc
    14161 tgattcatgt aaagattgtg taaagaatca aaaaaagcca cttttgaaaa atggctgctc
    14221 ctaaaaatag ctttaaaaat tattagtcct gtgcgaaaga ttggttagga agaaaaatcg
    14281 tgaagcaact gcctctgcca agctgactcg tcaccgtgac ttggccacct aataattgac
    14341 tgagttcttt gacaatggca aggccaagac cagtgccacc agtttgtctg cttcgacctt
    14401 tattaactcg gtaaaaacgt tcaaaaatac gatcctgctc taattgacta ataccaatcc
    14461 ctgtatctga tacagaaatc ttaatgcctt cgttcacctt ttgggtcttg acctcaattt
    14521 ttcccccttg ttcagtgtaa cggatggcat tggataaaag attgagtaag atttgggaaa
    14581 gtaattgact atctgatacg agggtgacat catctggcac ctgcaccttt agctgtaaat
    14641 ccttcttctt gagctgaggt tgcaagcttt gagtcaaatc ctgtacaaat tctgccaaag
    14701 aaagggtcgt ccattgtata ggcatttgtt gagccttaga taaggtaaga agatgctcaa
    14761 caatatgctc aagacgcaag ctttctttgt aaataatgtc tagaaagtca tccttgagcg
    14821 cttcttcttc agctgacatc cccttaatgg tttcagcaaa gcccttaatc gaagtaactg
    14881 gtgtcctcaa ttcatgggag gcatttgaga caaaggctaa atttaacttt tcataagttc
    14941 taatcgttgt taaatcatat agcaagacga gcacagcttc cacagattgg gtggggctaa
    15001 aaacgggaac tgctgtcact tctaaaatca agtcaccctc atgaaaccca cttacttctt
    15061 gttttaacct tgttttttga tcaaaggctt ggtgaactaa atttcgaata tccatccgtt
    15121 tgaggtcatc aagtgaactt atgtcgccgt ccacatcggg aaaataatga ggcagagagc
    15181 gactggataa taacatctga ccttgagcgg aaactaaaaa cgtccccatg gttaggtgcg
    15241 acagaagaac ctccattgtt tcggctaggt ccttgtattg ctgatcctgt tgggagactt
    15301 tggtttttag ggcagacaca tactgagcca aagactttaa gtcttcttgc cctttttcta
    15361 aaaagtattc actactggtc aagagaggtt ggtgcaaggt ctcaaaagca acttcccatt
    15421 tccaaaggca aaagagccag tagccacctt gtcccaaaga aagggctaga agaaagagac
    15481 cgatgccttt actgatccaa gttaatgcca tccctgcaat cagaatgagg ctaacactta
    15541 gattgactag ccaaaattga aggtagcgtt tcatctataa ctccttgaac ttataaccat
    15601 aaccccgaat ggttcgaata aattgagggg ctttaggatt gtcttcaatt ttttccctca
    15661 acttaccaat atgaacgtcc accaaacgtg tttcctgccc aaagtcatac ccccagatac
    15721 gttccaaaag acgctctcta gtcagtgtca tgttgggatg tttcataaga tagagcaaga
    15781 gttcaaattc ttttggggtc aaactcagta acttattcgc cttgtagact tcatgacgct
    15841 cagggtatac tttcaaggtc ccaaatagcc aagaatcgtc agcgatatta tctgaatcat
    15901 ctccttcttg ttctccttta gttcgcctga ggacagcctt gacacgcgcc agcaattctc
    15961 tagggctaaa aggcttggtc aggtagtcat cagcccctaa ttccaaggcc aaaaccttat
    16021 caaattcatc acttttcgca gaaaccatca taattggagt tttgacgcct ttggctctca
    16081 gccgcttaca aacttccatg ccatctaatt gtggtaacat gatatcaagc aagataaaat
    16141 caaagggttc tgtttctgcc aaagctaagg ccttccgtcc atttgttacc aattgagtag
    16201 aaaagccttc cttacttaaa tggtagtcaa gcaatttcag aatgtgttct tcatcatcca
    16261 ctaataagac ttgttttgtc atctattatc tcctattggt aacattataa cacaattatc
    16321 agaaatccta acattgctaa atcagattaa atttgcttat caagactagt atctggtcaa
    16381 acgctcaatc atctccttgt gctctggata ggtcgccagt agatctaccc tttcaaataa
    16441 ttcaaaatcc tcaaattcaa aaccaggagc aacaagacaa gaaaccagag cataatcctt
    16501 atcaactgtt gatccccaaa tagtgccctt aggaacacag tagtgaagtt gttgcccttt
    16561 ggatatgtcc aggcctaaag tgactgcttc gtagtgacca tctgctgtaa tcatgtgaac
    16621 agtaagtggg gatcctgcat gaaaatacca gatttcatct gctgtcaatc ggtgaaaatg
    16681 tgaaggattc gtttcttctt aataagaaat aaatactggt ataaagcgcc cttcccttac
    16741 cagcaaggtt tatagtgtct gaagcttttt ttgtttgtct aaaatagcca ccttcaacat
    16801 ggggagctaa ctctagagtt cttatcaagt cttctttatc cgtcggagcc aatgggttga
    16861 agtaactctt gttcaaagtg gtgttacgat ttcaagaact cctctcagtt ctgaggacac
    16921 ggtaatgatt gatgcgacgg aagtacaaat caatcgccct aaaaaaagaa ttagcgaatt
    16981 attctggtaa aaagaaattt cacgttatga aggctcaagc gattgtcaca agtcaaggga
    17041 gaattgtttc tttggatatc gctgtgaact attgtcatga tatgaagttg ttcaaaatga
    17101 gtcgcagaaa tatcggacaa gctggtaaaa tcttggctga cagtggttat caagggctca
    17161 tgaagatata tcctcaagca caaactccac gtaaatccag caaactcaag ccactaacag
    17221 ttgaagataa agcctataac catgcgctat ccaaggagag aagcaaggtc gagaacatct
    17281 ttgccaaagt aaaaacgttt aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct
    17341 tcggattacg aatgaatttg attgctggtc ttatcaatca tgaactagga ttctagtttt
    17401 gcaggaagtc tattatttgg ttaggtgaat tagtgaagcg tttaggcaag tgtctctggt
    17461 tacgacgtaa agaagcataa atcgataata tttatgtttc tttactagtg aaacgcctag
    17521 ccaaattacc atagttacga cgtcatggcc tctaaatcga ttatatttag gggtcatgac
    17581 tagtgaagca gttagctagt tcgcatataa gcggctagcg tctaacaatt aggaacttta
    17641 gttccaataa ctttaagatt acgacgtttt aggacataaa tcgatcatat ttatgtccta
    17701 aaactagtga agcgcctagc caaagtccga ataggatttg gcgttagtta cttagattgc
    17761 tttgcaatca agtaactttg gcgatttaca tcttctctgg cgcttctact ccaagcaagc
    17821 gaagggcttc tttgagaacg actgcggttg cgtagctgag ggctagacgg ctgtcgcgtt
    17881 ctgggctttc atccaagata cgtgtatgtg catagtattt gttaaaggat tgagccaggc
    17941 taattgcaaa tttagcaatg atagaaggtt caaagttatc tgccgcacgg ttgataatac
    18001 gtgggaagtc ttgaatgagt ttaatgattt cccagctttc agtatcattc aagctatagt
    18061 tgccagctgt ttctggtttg aaatcggctt tacgtaagat agattggata cgagcgtagg
    18121 catattgaac gtaaggtcca gtttcaccct cgaaggatac catagcttct aggtcgaagt
    18181 cgtatccatt tgtacggtcg gttttgaggt catagaattt aatggctcca accccaacag
    18241 catgtgctac ctgatcttta ttttccaatt caggattttt tgcttcaatt tgggctttgg
    18301 cacggctaac agcctctgca acagtaggct ctagcaagat gacattccct ttacgagtag
    18361 agagtttctt cccttctttt gtaaccagac caaaaggaac gtgagtaatg tcgtcactcc
    18421 agtcgtagcc catctcttgc aagacagctt tgagctgttt aaagtgggca gattgttctt
    18481 gaccaacgac atagatagat ttagcaaatt ggtattcgtt tttacggtaa agggctgcag
    18541 ccaagtcacg tgtgatatag agagttgcac catcagactt cttgatgagg gcgggatgtt
    18601 caattccata tttctcaagg ttcacaactt gggcaccttc tgattcaaga agtagtcctt
    18661 tttcagaaag aatgtctaca actgcatcca tcttatcatt gtagaaggct tctccgttat
    18721 agctgtcaaa ttcaaccttc aattcattgt aaaggcggtt aaattccact aaactttcat
    18781 cgcggaacca ttgccaaaga gcgagagctt cctcatctcc attttcaagt ttacggaacc
    18841 attcgcgcgc ttcttcatcc aagctagggt cattttcagc ttcagcgttg atgcggacat
    18901 agagtttaag gagttcatcg attggatgag cttttacagc ttcttcgtcg ccccattttt
    18961 tgtaggcaac aatcaacatc ccaaattgtt taccccagtc tcccaaatgg ttgaccttga
    19021 ccgtttgata accgattttt tggaaaatat gtgacaagct atctccgata acagttgaac
    19081 gcaggtggcc aatagaaaat ggtttagcga tattcggact agacatgtcg ataacaacat
    19141 tttcttgttt accaatattt tggtcagcat agtgttcttt ttcagtggta acagcttgca
    19201 atacttgagc agaaatggca gatttatcaa ggaaaaagtt aacgtaaggt cctgttgcga
    19261 caaccttttc aaaggcttgg ctgttcattt tttcagccag ttcagtcgca atcatttgag
    19321 gtgctttacg ttcgactttt gcaagagaaa aagcagggaa agcgatgtct cccatttctg
    19381 agtttttagg ggtttccagt aaatttaaaa tagcctcttg gtccaggcta tcaatgatgc
    19441 tagataattc gctagcaatc aattcttttg tattcattaa gagctccttt ttggactttt
    19501 ctactatttt atcacaattt taaagaaaga agaaaaaatt tttgaaatct cccgtttttt
    19561 tggtataata tagctataaa tatagttata aatatacata taagaggatt ttatgagaaa
    19621 aagagatcgt catcagttaa taaaaaaaat gattactgag gagaaattaa gtacacaaaa
    19681 agaaattcaa gatcggttgg aggcgcacaa tgtttgtgtg acgcagacaa ccttgtctcg
    19741 tgatttgcgc gaaatcggct tgaccaaggt caagaaaaat gatatggtgt attatgtact
    19801 agcaaatgag acagaaaaga ttgatttggt ggaatttttg tctcatcatt tagaaggtgt
    19861 tgcaagagca gagtttacct tggtgcttca taccaaattg ggagaagcct ctgttttggc
    19921 aaatattgta gatgtaaaca aggatgaatg gattttagga acagttgctg gtgccaatac
    19981 cttattggtt atttgtcgag atcagcacgt tgccaaactc atggaagatc gtttgctaga
    20041 tttgatgaaa gataagtaag gtcttgggag ttgctctcaa gacttatttt tgaaaaggag
    20101 agacagaaaa tggcgataga aaagctatca cccggcatgc aacagtatgt ggatattaaa
    20161 aagcaatatc cagatgcttt tttgctcttt cgtatgggtg atttttatga attattttat
    20221 gaggatgcgg tcaatgctgc gcagattctg gaaatttcct taacgagtcg caacaagaat
    20281 gccgacaatc cgatccctat ggcgggtgtt ccctatcatt ctgcccaaca gtatatcgat
    20341 gtcttgattg agcagggtta taaggtggct atcgcagagc agatggaaga tcctaaacaa
    20401 gcagttgggg ttgttaaacg agaggttgtt caggtcatta cgccagggac agtggtcgat
    20461 agcagtaagc cggacagtca gaataatttt ttggttgcca tagaccgcga aggcaatcaa
    20521 tttggcctag cttatatgga tttggtgacg ggtgactttt atgtgacagg tcttttggat
    20581 ttcacgctgg tttgtgggga aatccgtaac ctcaaggctc gagaagtggt gttgggttat
    20641 gacttgtctg aggaagaaga acaaatcctc agctgccaga tgaatctggt actctcttat
    20701 gaaaaagaaa gctttgaaga ccttcattta ttggatttgc gattggcaac ggtggagcaa
    20761 acggcatcta gtaagctgct ccagtatgtt catcggactc agatgaggga attgaaccac
    20821 ctcaaacctg ttatccgata cgaaattaag gatttcttgc agatggatta tgcgaccaag
    20881 gctagtctgg atttggttga gaatgctcgc tcaggtaaga aacaaggcag tcttttctgg
    20941 cttttggatg aaaccaaaac ggctatgggg atgcgtctct tgcgttcttg gattcatcgc
    21001 cccttgattg ataaggaacg aatcgtccaa cgtcaagaag tagtgcaggt ctttctcgac
    21061 catttctttg agcgtagtga cttgacagac agtctcaagg gtgtttatga cattgagcgc
    21121 ttggctagtc gtgtttcttt tggcaaaacc aatccaaagg atctcttgca gttggcgact
    21181 accttgtcta gtgtgccacg gattcgtgag attttagaag ggatggagca acctgctcta
    21241 gcctatctca tcgcacaact ggatgcaatc cctgagttgg agagtttgat tagcgcagcg
    21301 attgctcctg aagctcctca tgtgattaca gatgggggaa ttatccggac tggatttgat
    21361 gagactttag acaagtatcg ttgcgttctc agagaaggga ctagctggat tgctgagatt
    21421 gaggctaagg agcgagaaaa ctctggtatc agcacgctca agattgacta caataaaaag
    21481 gatggctact attttcatgt gaccaattcg caactgggaa atgtgccagc ccactttttc
    21541 cgcaaggcga cgctgaaaaa ctcagaacgc tttggaaccg aagaattagc ccgtatcgag
    21601 ggagatatgc ttgaggcgcg tgaggagtca gccaacctcg aatacgaaat atttatgcgc
    21661 attcgtgaag aggtcggcaa gtacatccag cgtttacaat ctctagccca aggaattgcg
    21721 acggttgatg tcttacagag tctggcggtt gtggctgaaa cccagcattt gattcgacct
    21781 gagtttggtg acgattcaca aattgatatc cagaaagggc gccatgctgt cgttgaaaag
    21841 gttatggggg ctcagaccta tattccaaat acgattcaga tggcagaaga taccagtatt
    21901 caactgatta cagggccaaa catgagtggg aagtctacct atatgcgtca gttagccatg
    21961 acggcggtta tggcccagct gggttcctat gttcctgctg aaaccgccca tttaccgatt
    22021 tttgatgcga tttttacccg tatcggagca gcagatgact tggtttcggg tcagtcaacc
    22081 tttatggtgg agatgatgga ggccaataat gccatttcgc atgcgaccaa gaactctctc
    22141 attctatttg atgaattggg acgtggaact gcaacttatg acgggatggc tcttgctcag
    22201 tccatcatcg aatatatcca tgagcacatc ggagctaaga ccctctttgc gacccactac
    22261 catgagttga ctagtctgga gtctagttta caacacttgg tcaatgtcca cgtggcaact
    22321 ttggagcagg atgggcaggt caccttcctt cacaagattg aatcgggacc agctgataaa
    22381 tcctacggta tccatgttgc caagattgct ggcttgccag cagacctttt agcaagggcg
    22441 gataagattt tgactcagct agagaatcaa ggaacagaga gtcctcctcc catgagacaa
    22501 actagtgctg tcactgaaca gatttcactc tttgataggg cagaagagca tcctatccta
    22561 gcagaattag ctaaactgga tgtgtataat atgacaccta tgcaggttat gaatgtctta
    22621 gtagagttaa aacagaaact ataaaaccaa gactcactag ttaatctagc tgtatcaagg
    22681 agacttcttt gacaattctc cacttttttg ctagaataac atcacacaaa cagaatgaaa
    22741 aggagctgac gcattgtcgc tcccttttgt ctatttttta aggagaaagt atgctgattc
    22801 agaaaataaa aacctacaag tggcaggccc tggcttcgct cctgatgaca ggcttgatgg
    22861 ttgctagttc acttctgcaa ccgcgttatt tgcaggaagt cttagacgcc ctccttactg
    22921 ggaaatatga agctatttat agtatcgggg cttggttgat tggtgtggcc gtagtcggtc
    22981 tagttgctgg tggactcaat gttgtcctcg cagcctatat tgcccaagga gtttcatccg
    23041 accttcggga ggatgccttc cgtaaaattc aaaccttttc ttatgctgat attgaacaat
    23101 ttaatgcggg aaatctagtc gttcgaatga caaatgatat caaccagatt cagaacgttg
    23161 tcatgatgac cttccaaatt cttttcagac ttcccctctt gttcatcggt tcgtttatcc
    23221 tagcggttca aaccttacct tctctgtggt gggtgattgt tctcatggta gtcttgattt
    23281 ttggtttgac tgctgtcatg atgggaatga tggggcctcg ttttgctaag tttcaaaccc
    23341 ttcttgagcg catcaatgcc attgccaagg aaaatttacg tggcgttcgt gtggtcaagt
    23401 cctttgtcca agaaaaagag caatttgcta agtttacaga ggtctcagac gagcttcttg
    23461 gtcaaaactt ttacattggt tatgcctttt cagtagtgga accctttatg atgttggttg
    23521 gttacggggc ggtcttcctc tctatttggc tggtcgcggg aatggttcag tcggatccgt
    23581 ctgttgttgg ttccatcgct tcttttgtta attacctaag ccagactatc tttaccattg
    23641 ttatggttgg atttttggga aattctgtca gccgtgccat gatttccatg cgtcgtattc
    23701 gagaaattct tgacgcagag ccagctatga ccttcaagga tatcccagat gaagagttgg
    23761 ttggaagcct tagctttgaa aatgtgacct ttacctatcc aatggacaag gaaccgatgc
    23821 tgaaagatgt gagctttact attgaacctg gtcaaatggt tggtgtagtt ggagcgactg
    23881 gtgcaggaaa gtcaaccttg gctcaattga ttccacgtct ctttgatcca caggacgggg
    23941 ccgttaaaat cggtggcaag gatattcgag aagtgagtga aggaaccctg cgtaaaacag
    24001 tttccatcgt tctccaacgt gccattcttt ttagtggaac gattgcagat aacttgagac
    24061 aggggaaggg aaatgctact ctatttgaaa tggagcgtgc agccaatatt gcccaggcta
    24121 gtgaattcat tcatcgtatg gagaaaacct ttgaaagtcc agttgaagaa cggggaacca
    24181 atttctctgg tggacaaaaa caaaggatgt cgattgcgcg tgggattgtc agcaatccac
    24241 gtattctgat ttttgacgat tcgacctcag ccttggatgc caagtcagag cgcttggtgc
    24301 aagaagcttt gaataaggac ttgaagggga cgacaaccat tattattgct caaaaaatta
    24361 gctcggttgt ccatgcagac aagatcttgg ttctaaatca aggacgattg attggtcaag
    24421 gcacgcatgc agacttggtt gccaacaatg ccgtttaccg tgaaatctat gaaacacaga
    24481 aatgaaagac aaactataag aaaagtcaat agttttatct aaactatttc ttatttcaat
    24541 ttgatgattt ggcgatgatt ttagagcacg gcaaaaagcc cttgaaaaag tccatttttc
    24601 aaaggtaatc ctgtgttaat ttcagaaatt acatcacttt ttgttcgtca aatggcagct
    24661 cttttttagg atataaaaca gggttcggat aagttttttt gcaaggtgga tgatggttat
    24721 attgtaatgt tttccttatt ctaacttagt cttaagatag gccttaaaag taggcgaaaa
    24781 gcgagcgcat gctttggcaa cttgtatgag tacctaccgc agatgagggg aaccccgttt
    24841 gaccattctt cctgctaaat caatctgacc tgactgataa atagaagaat ccagtccagc
    24901 gaaagcttgt aattgagcag gattatcaaa ggcatgaata tttcgaatct cggctaaaat
    24961 gaccgcccct aaacgattcc caatcccagt aaccgtcgtg atgaccgagt tgaactcagc
    25021 catcaagtca ttgacacatt tttccgcttt gtcaatgatc ctcttgtaat gtttgatgtt
    25081 ttcattacac gagataaaac gtttatgcgt tatcaaactc attaccaatt gaaacaaaag
    25141 ctgtggttag agcctttcgg aaattgtcaa gcgattggag gaaatgaact aatccacagc
    25201 ggcttattcc aagtatacca cttgggcttt ggcagtagct aactgcgcta aatataatat
    25261 aaggaggagt aaaatgaaga cagttcaatt tttttggaat tattttaagg tctacaagtt
    25321 ctcatttgta gttgtcatct tgatgattgt tctggcgact tttgcccaag ccctctttcc
    25381 agtcttctct ggacaagcgg tgacgcagct agccaattta gttcaagctt atcaaaatgg
    25441 caatccagaa cttgtatggc aaagcctatc aggaatcatg gtcaatcttg gtctgctggt
    25501 tttggttcta tttatttcta gtgtaatata catgtgtctc atgacgcgcg tgattgcaga
    25561 atcgaccaac gagatgcgca aaggcctctt tggtaagctt gctcagttga cggtttcttt
    25621 ctttgaccgt cgacaagatg gcgatatcct gtctcatttt accagtgatt tggataatat
    25681 cctccaagcc tttaacgaaa gcttgattca ggtcatgagc aatgttgttt tatacattgg
    25741 tctgattctt gtcatgtttt cgagaaatgt gacgctggct ctcatcacca ttgccagcac
    25801 cccattggct ttctttatgc tgattttcat cgtgaaaatg gcacgcaaat ccaccaacct
    25861 ccagcagaaa gaggtaggga agctcaacgc ctatatggat gagagcatct caggccaaaa
    25921 agccgtgatt gtgcaaggaa ttcaagagga tatgatggca ggatttcttg aacaaaatga
    25981 gcgcgtgcgc aaggcaacct ttaaaggaag aatgttctca ggaattcttt tccctgttat
    26041 gaatgggatg agcctggtta atacagccat cgtcatcttt gctggttcgg ctgtgctttt
    26101 gaatgataag tctattgaaa caagtacagc cctaggtttg attgttatgt ttgcacaatt
    26161 ttcacagcag tactaccagc ctattatcca agttgcagcg agttggggaa gccttcagtt
    26221 ggcctttact ggagctgaac gaattcagga aatgtttgat gcagaggagg aaatccgacc
    26281 tgaaaaggct ccaaccttca ctaagttgca agaaagtgtt gaaatcagtc atatcgattt
    26341 ttcatacttg cctgataaac ctattttgaa agatgtcagc atttctgccc ctaaaggcca
    26401 gatgacagca gttgttgggc cgacaggttc aggaaaaacg actattatga acctcatcaa
    26461 tcgcttttat gatgttgatg ctggtggtat ttattttgat ggtaaagaca ttcgtggcta
    26521 tgacttagat agtcttagaa gcaaggtggg aattgtattg caagattcgg tcttgtttag
    26581 cggaacgatt cgagacaata tccgatttgg tgtgccagat gctagtcagg aaatggttga
    26641 ggtagcagca aaagcaaccc acattcacga ctatatcgaa agtttgcctg ataagtacga
    26701 tactcttatt gatgatgacc agagcatctt ttcaacaggg cagaagcaat tgatttcaat
    26761 cgctcgaacc ctgatgacag atccagaagt tctcattctc gatgaagcaa cttcaaacgt
    26821 agatacggtg acagaaagca agattcagca tgccatggag gtggttgtag caggtagaac
    26881 tagtttcgtc attgcccacc gcttgaaaac cattctcaat gcagatcaga ttattgtcct
    26941 taaagatgga gaagtcattg aacgtggtaa ccaccatgaa cttttgaagc taggtggctt
    27001 ttattcagaa ctctatcaca atcaatttgt tttcgaataa gaaagaagtt gtcctatgtg
    27061 ggcagctttt tcttgtccat aaaaaatgtt tatcacagcc ttaaaaaaaa catattagac
    27121 gaaagtcatt ttgagtgata tgataggact atcgttagca ttcgaaagga gaggcatcat
    27181 ggctagaacg gttgtaggag ttgctgcaaa tctatgtccc gtagacgcag aaggcaaaat
    27241 cattcattca tctgtatctt gtagattcgc agagatcatt cgtcaagtcg gtggtctccc
    27301 tttagtcatt cctgttggtg atgagtcagt tgtacgtgat tatgtggaaa tgattgacaa
    27361 gctcattttg acaggaggcc aaaatgttca tcctcagttc tatggagaga aaaagaccgt
    27421 cgagagcgat gattacaatc tggtccgtga cgaatttgaa ttggcactct tgaaggaagc
    27481 gcttcgtcag aataaaccaa ttatggcaat ctgtcgcggt gtccaacttg tcaatgttgc
    27541 ctttggtgga accctcaatc aagaaatcga aggtcactgg caaggactac ctttagggac
    27601 atctcactct attgagacag tagaaggaag cgtggtggct aagctatttg ggaaagaaag
    27661 tcaggtcaac tcagtccatc gtcaaagcat taaagatttg gcacctaatt tccgtgtaac
    27721 tgctattgat tcaagagacc aaactattga agcgattgag tctatcgacg agcaccgcat
    27781 tatcggttta cagtggcatc cagagtttct ggttaatgaa gaagatggca atttagaatt
    27841 atttgagtat ttattgaatg aactgtaacg attggaacat ctggtcgttc tttcttttat
    27901 tttttcaaaa tttttagaat gtggcatttt tacgcaaacg tttgaattct gataaaaatt
    27961 ggagaaattc gacaaaaaac ttgaaaaaaa cgaaggtaag cgttatgata gaaaagaaga
    28021 aatattggag gaagaacatg tcacatatta aatttgatta ttcaaaagtt ttagacaaat
    28081 ttgttgcacc acatgaagtg gaatacatgc aatcacaagt aacagcagca gatgaattga
    28141 tccgtaaagg aactggtgct ggtagcgact tcttgggatg gttggacctt cctgaaaaat
    28201 acgaccgcga agaatttgac cgcatcttga aagctgctga gcaaatcaag tcagacagcg
    28261 atgttttgat tgtgatcggt attggtggat cttaccttgg tgcaaaagca gcaatcgact
    28321 tcttgaatca ccattttgct aacttgcaaa caaaagaaga acgcaaagcg ccacaaatcc
    28381 tttacgcagg aaactcaatc tcatctactt accttgctga cttggtagag tatgttgcag
    28441 acaaagactt ctcagtaaac gtaatttcta aatcaggtac aacaactgaa ccagcgattg
    28501 ctttccgtgt ctttaaagaa ctcttggtta agaaatatgg tcaagaagaa gctaacaaac
    28561 gtatctatgc aacaactgac cgccaaaagg gtgctgttaa ggttgaagca gacgctaaca
    28621 gttgggtaac atttgttgtt ccagatgata tcggtggacg cttctcagta ttgacagccg
    28681 ttggtttgct tccgatcgca gcatcaggag ctgacatcaa atctcttatg gaaggtgcga
    28741 atacagctcg caaagactac acttcagaca aaatctctga aaacgaagct taccaatacg
    28801 cagccgttcg taacatcctt tatcgtaaag gctatgcaac tgagatcttg gtaaactatg
    28861 agccatcact tcaatacttc tcagaatggt ggaaacaatt ggctggtgaa tcagaaggaa
    28921 aagaccaaaa aggtatctac ccaacttcag ccaacttctc aactgacttg cattcacttg
    28981 gtcaatttat ccaagaagga actcgtatca tgtttgaaac agttgtccgt gttgacaaac
    29041 ctcgtaaaaa cgtgcttatt cctactttgg aagaagacct tgacggactt ggttaccttc
    29101 aaggaaagga cgttgacttt gtaaacaaaa aagcaactga cggtgttctt cttgcccaca
    29161 cagatggtga tgtaccaaac atgtatgtga ctcttccaga gcaagacgct ttcactcttg
    29221 gttacactat ctacttcttc gaattggcaa ttgccctttc aggttacttg aatgctatca
    29281 acccatttga ccaaccaggt gttgaagctt ataaacgtaa catgtttgcc cttcttggaa
    29341 aaccaggatt tgaagaattg agcaaagaac ttaacgcacg tctataatag aagaaaagag
    29401 tggtttgccc actcttttta ctctctttat ccatagaaat tggactcagc caagacttgt
    29461 gatataatat agaaagcaaa aaggcagacg cctagataat aggagaaact atgttaaaag
    29521 atatccgcgt acgttacgca ccaagtccaa caggactact acacatcgga aatgctcgta
    29581 cagcattgtt taactacttg tatgcgcgcc atcatggtgg aacatttctc atccgtatcg
    29641 aagatactga ccgtaaacgc catgtcgagg atggtgaacg ttcacaactt gaaaaccttc
    29701 gctggttagg catggattgg gatgaaagtc cagaatcaca tgagaattat cgccagtctg
    29761 agcgtttgga cttgtatcaa aaatacattg accaactatt agctgaagga aaagcctata
    29821 aatcttacgt tacagaagaa gagttggcag ctgaacgcga acgccaagaa gtagctggcg
    29881 aaacaccacg ctacatcaat gaataccttg gtatgagtga agaagaaaaa gcagcttaca
    29941 tcgcagaacg tgaagcagca ggggtcaccc caactgttcg tttggctgtc aatgagtcag
    30001 gtatctacaa gtggcatgat atggtcaaag gcgatattga atttgaaggt ggcaatatcg
    30061 gtggtgactg ggttatccaa aagaaagacg gttacccaac ttacaacttt gccgttgcca
    30121 tcgatgacca tgatatgcaa atctcccatg ttatccgtgg agacgaccat attgctaaca
    30181 caccaaaaca gctcatggtt tatgaagcac ttggttggga agctccagag tttggtcaca
    30241 tgaccttgat tatcaattct gagactggta agaagttatc taaacgtgat accaacaccc
    30301 ttcagtttat cgaagactac cgtaaaaaag gttatttacc agaagcagtc tttaacttta
    30361 ttgctcttct tggttggaac ccaggtggtg aagatgagat tttctctcgt gaagaactca
    30421 ttaaactttt tgatgaaaac cgcctcagca agtcaccagc agcctttgat cagaaaaaac
    30481 tagactggat gagcaatgat tatatcaaga atacagacct tgaaaccatc tttcaaatgg
    30541 caaaaccatt cttagaggaa gcaggctgtt tgactgacaa ggctgaaaaa ttagttgagc
    30601 tctataaacc acaaatgaaa tcagtagatg agattatccc attgacagat cttttcttct
    30661 cagatttccc agaattgaca gaagcagagc gcgaagtcat gacgggtgaa acagttccaa
    30721 cagttcttga agcattcaaa gcaaaacttg aagcgatgac agatgatgaa tttgtgacag
    30781 aaaatatctt cccacaaatt aaagcagtcc aaaaagaaac aggtattaaa gggaaaaatc
    30841 ttttcatgcc tattcgtatc gcagtttcag gcgaaatgca tgggccagaa ttaccagata
    30901 caattttctt gcttggacgt gaaaaatcaa ttcagcatat cgaaaacatg ctaaaagaaa
    30961 tctctaaata aagaggatac aataatggac atctgggaaa agatgtacga agaagcacag
    31021 aaactataca atccacatga agtatcagac tttgtttatg ccaatcatgt tgtagctgca
    31081 gtagaagcag aagatggaca aatatttaca ggattctgta tggagggaac ctgtggtgtt
    31141 ttccatctct gcgcagaacg ggcggccctc ttcaatatgt accaattttc aggacaaact
    31201 aaggttaaga aagtattagc ctttcgagat aaaccacctt atggcggaag ttcagccatt
    31261 ccttgcggtg cttgtagaga attcctttta gagcttaatg ctgaaaataa agatgcagaa
    31321 ttcatgatgg actataatat aagaaaaaca gttaaagtcg cagaactaat cccttattgg
    31381 tggggagaag aacgtgcttc taagtttaat gagcgataga agagtcagta taattctggc
    31441 tctttttact ataagtt
//
LOCUS       DAVDZK010000027        30759 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVDZK010000027 DAVDZK010000000
VERSION     DAVDZK010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30759
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.028"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            114..1244
                     /locus_tag="VUX16_001412"
     CDS             114..1244
                     /locus_tag="VUX16_001412"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET8124361.1"
                     /translation="MKKRSETIKYRRIVFKVGTSSLTNEDGSLSRSKVKAITQQLAML
                     HESGHELILVSSGAIAAGFGVLGFKKRPTKITDKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLSRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            1254..2516
                     /locus_tag="VUX16_001413"
     CDS             1254..2516
                     /locus_tag="VUX16_001413"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET8124362.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTVL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASFLPRLDQ
                     MLVAERKEVGLEPIQFRLDSKASQFVSGQVAEAQDFDTEFLDYVLAVKVVSSLEEAVT
                     HIETHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            2520..3317
                     /gene="proC"
                     /locus_tag="VUX16_001414"
     CDS             2520..3317
                     /gene="proC"
                     /locus_tag="VUX16_001414"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET8124363.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDELLLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVGLGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEVHAFRGTVMDAVHQAYKRTQELGQ"
     gene            3537..4175
                     /locus_tag="VUX16_001415"
     CDS             3537..4175
                     /locus_tag="VUX16_001415"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET8124364.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLLILEEKGVEVLTSREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            4172..5062
                     /locus_tag="VUX16_001416"
     CDS             4172..5062
                     /locus_tag="VUX16_001416"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET8124365.1"
                     /translation="MKQEQLKAWQPAQFDRFVRILEQDQLNHAYFFSGFFGSLEMAQF
                     LAKSLFCTDKVDVLPCENCRNCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEQLILLLEQMGLVKKKATLLAQFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRVLEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            5102..5419
                     /gene="yabA"
                     /locus_tag="VUX16_001417"
     CDS             5102..5419
                     /gene="yabA"
                     /locus_tag="VUX16_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET8124366.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            5422..6291
                     /gene="rsmI"
                     /locus_tag="VUX16_001418"
     CDS             5422..6291
                     /gene="rsmI"
                     /locus_tag="VUX16_001418"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET8124367.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKVGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            6509..7564
                     /locus_tag="VUX16_001419"
     CDS             6509..7564
                     /locus_tag="VUX16_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET8124368.1"
                     /translation="MKKYNIVDLFSGAGGLSYGFEMAGFNVLLGIDNDEKALETFQKN
                     HQNSEILCGDIANISYEEDIKPIIGEQKIDIIVGGPPCQGMSLSGPRRFDDPRNKLYL
                     SYIRLVREIQPTAFVIENVIGIVSLFKGQIKDTIIEEFSKMGYKVQFKVLLASDYGVP
                     QNRKRVIFVGTRNDGFEYPEALGTIITTEMAISDLPTLENELGEIEMSYVSEPQNDYQ
                     KLMRKRSNVVLNHVAAKHSEKVISTIALVPDGGNYKNLPKELRETRKFNVAWTRFASW
                     KPAPTIDTGHRHHFHYKYNRVPTVRESARLQSFPDDFIFYGSKTQQFRQVGNAVPPLM
                     AQQIANNLLKYLKNNEE"
     gene            7567..8967
                     /locus_tag="VUX16_001420"
     CDS             7567..8967
                     /locus_tag="VUX16_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET8124369.1"
                     /translation="MYQVPEKYYFRLHHPRPRFKNDVENVLVYMATNISYLGILPKKE
                     FSQQLNDIIKQYAGNADKTEKTINNWRTEISSLFGMMIEKEGFVYSGNRAKELTEDQD
                     LIRFFKTFLYNFEYPGGHLKDNEIVKLCQIGVQFKPAQYLLELFTEASQAEEKTIYLT
                     DEEVAHCIFNDLRCTRDREPVLEIWNRIKENRASKVAYDTKGDVIRYAKDVLDYMVIA
                     SLLTVQGGRYKINSMEEQATNDFLQSDATFDGYAQFIGNASTTIEDVRNFRSAWFEYV
                     NRDLGDIDFRTNFNLYLPSDIDFTEEKTDIIGHLTEHIEYSEKISTAVVGSSGEAIVI
                     NHEKQKLREHGQEQLLHLVNFIPTQFGVGYDVQSFECDDSELRKYIEVKTTVSNASIT
                     FNSFHITPNEWRTAKSVRDRYYIYRLQISKHSKKLFIIKNLYELVKNEKMLLIERKDG
                     YDARFSSSVGFEENLI"
     gene            8964..10004
                     /gene="dcm"
                     /locus_tag="VUX16_001421"
     CDS             8964..10004
                     /gene="dcm"
                     /locus_tag="VUX16_001421"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET8124370.1"
                     /translation="MKKLKIASLFSGGGGTDIGFAGGFDFLGKHYADNQIEIVYANDI
                     EDSANKMFEKNFGVTPDNRNIREIKSDEIPSFDILTGGFPCQSFSVSAQNPKRLGIKD
                     EKGTLFFEMVRVLKAHQPKAFFAENVKGILSANNKEAFPLIIEEFEKAGYNVSYKLCV
                     ATKYGVPQKRERVFIVGIRKDLNFTFEFPEEPIQNVEDYTPLKVILQQDIDEKYYFSE
                     RAVQGMLNSKSGKKMNKGRAQDIEQPSNTVSSHLAKVSLNSTDPVLLENGRYRRYTPR
                     EVARIQSFPENYELLGSEGAQYRMLGNAIPPVMMWYIAEKLVSDLRNSDVIAKQQKLE
                     ESFGQLDLFEAS"
     gene            10029..10823
                     /locus_tag="VUX16_001422"
     CDS             10029..10823
                     /locus_tag="VUX16_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HET8124371.1"
                     /translation="MELNFQDKSFIKVFFNSDGYVLNFSNSTFANFTFNSVGVNIQEK
                     YGGSKGKALQAFVDNEPDELVLKLALDLLRYYEDLPDSYYEKTEERNSQALKLKERLS
                     KYEVSQIAYLNNAAKSLSDYFDSDYIDKQMGIMNEMISRSPADAIGKAKELLESCFKH
                     ILDHEKIEYSNSNDIATLQKKVFKFLNLDSNENISAKNNQDVKVVLSGLNQIIKGINN
                     LRNDKGDGHGKGANFIELPPRYASVVVGSALTVVSFVWETYQDKQK"
     gene            10841..11404
                     /locus_tag="VUX16_001423"
     CDS             10841..11404
                     /locus_tag="VUX16_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000042158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HET8124372.1"
                     /translation="MSKNQEKLHFQLKKFIVNVGWTHKIHAVRIDELESYIRWFRIAT
                     IIISGVVSSGLVGILWFDEYWIKLVTAFLSLVTTIIFSITKEFNFEERLALERKSVDE
                     LWNLRVLAEILLSEVVYNGKPSSEIQEFFEELKFRRDATYSQLSNASPKNVSKASKLI
                     KSRKDNDYEEDYRYFIPKELMEIKEEE"
     gene            11404..12726
                     /locus_tag="VUX16_001424"
     CDS             11404..12726
                     /locus_tag="VUX16_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET8124373.1"
                     /translation="MSLSNDFKEFCEDELPMTDEEWEKWENRLKEITKRLNRKFYSLD
                     ELDDQETDNGLIVGSVGRTTAVRNVSDFDYIFSLPSEVYRRFDSYEGNGQSALLQEIK
                     NELLKRYPNTKIKGDGQVVVIDFSDGGKIELVPAFEKSDGNFKYPDSRNGGSWKTTKP
                     KFEIEKCKSLNSNFNSHFSNLTRLIRQWKNHMGFSFKGLLIDTLISDLIDDKGISEIY
                     YSDYNILLKDIFEYFSNQDKNREYWYALGSNQKIYNNDGAKFVNKAKQALKKIEDASE
                     EKLTEVYRQLFGRKFAQSTSTTNRASNEEFIDELFNVNIEYNIVLECEITQDGFRKAL
                     LSDFLKSRFKIKNRKSLDFEIIKSDIPDNLLSDVKYYWKVRNIGAEAIRRNCERGAIF
                     SGKIKHHEDSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            13070..14404
                     /gene="trmFO"
                     /locus_tag="VUX16_001425"
     CDS             13070..14404
                     /gene="trmFO"
                     /locus_tag="VUX16_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET8124374.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESATSGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            14488..15213
                     /locus_tag="VUX16_001426"
     CDS             14488..15213
                     /locus_tag="VUX16_001426"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET8124375.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRSAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQPGNIKRVVFGENIGTTVSNNI"
     gene            15234..15791
                     /gene="frr"
                     /locus_tag="VUX16_001427"
     CDS             15234..15791
                     /gene="frr"
                     /locus_tag="VUX16_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET8124376.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLII
                     PVLTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            15851..16705
                     /gene="cvfB"
                     /locus_tag="VUX16_001428"
     CDS             15851..16705
                     /gene="cvfB"
                     /locus_tag="VUX16_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET8124377.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            16714..16929
                     /locus_tag="VUX16_001429"
     CDS             16714..16929
                     /locus_tag="VUX16_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET8124378.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            17015..17983
                     /locus_tag="VUX16_001430"
     CDS             17015..17983
                     /locus_tag="VUX16_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET8124379.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVILAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(17961..18140)
                     /locus_tag="VUX16_001431"
     CDS             complement(17961..18140)
                     /locus_tag="VUX16_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124380.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQQYI
                     LLQANFLKISRVQLQ"
     gene            18176..18676
                     /locus_tag="VUX16_001432"
     CDS             18176..18676
                     /locus_tag="VUX16_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124381.1"
                     /translation="MIDQLSKYYSCRILTEKNIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFIGFWNGSDLVAVMDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKACLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            18679..18939
                     /locus_tag="VUX16_001433"
                     /pseudo
     CDS             18679..18939
                     /locus_tag="VUX16_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(19306..20417)
                     /gene="ald"
                     /locus_tag="VUX16_001434"
                     /pseudo
     CDS             complement(19306..20417)
                     /gene="ald"
                     /locus_tag="VUX16_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            20594..21163
                     /locus_tag="VUX16_001435"
     CDS             20594..21163
                     /locus_tag="VUX16_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124382.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYTSDKGNTRY
                     TFPTNQILEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTPETNRAVIELAFEKIGMNKLVALYDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            21230..21880
                     /locus_tag="VUX16_001436"
     CDS             21230..21880
                     /locus_tag="VUX16_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET8124383.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            21864..24104
                     /locus_tag="VUX16_001437"
     CDS             21864..24104
                     /locus_tag="VUX16_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET8124384.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFALSFLYPVIQLNFIFEWLEGMIRLVSQVASRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKRLAVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESEKKIEKWQEKATTSNAQRTLIPYLKSRGVSKIDQLILTNTDKEHIGDL
                     LEVTKAFHVGEILVSKGSLKQKEFVVELQATQNKVRSVSVGENLLIFGSQLEVLSPRK
                     IGDGGHDDTLVLYGKLLDKQFLFTGNLEEKGERDLLRQYPDLEVDVLKASQHGSKTSS
                     SSAFLEKLKPEITLISVGKSNRTKLPHQETLTRLETINSKVYRTDQQGAIRFKGWKSW
                     KIESVR"
     gene            24504..25097
                     /locus_tag="VUX16_001438"
     CDS             24504..25097
                     /locus_tag="VUX16_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124385.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFEKGRIYGILAINGSGKTTLFR
                     TISNLIPISSGNIAAPPSLFYYESVEWLDGSLSGIDYLRLIKNIWKSDLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEVPL"
     gene            25094..26278
                     /locus_tag="VUX16_001439"
     CDS             25094..26278
                     /locus_tag="VUX16_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124386.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLLLFASVLGVTFYLNSQTANSVS
                     LESRLESRIVDNGRAINENEAKLSQMSDTSSEEYQFAKNNLDLQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFN
                     RS"
     gene            26497..26826
                     /locus_tag="VUX16_001440"
                     /pseudo
     CDS             26497..26826
                     /locus_tag="VUX16_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282476.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            27093..27371
                     /locus_tag="VUX16_001441"
     CDS             27093..27371
                     /locus_tag="VUX16_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124387.1"
                     /translation="MWLETIVCFDCDYEEKWEEDNIFKPIHCPECRDVLDVVERDWLG
                     ETILRSTVQCERCNFLFDHLDFQLGLSECPSCFSKELKLVRQKKEIVE"
     gene            27368..27532
                     /locus_tag="VUX16_001442"
     CDS             27368..27532
                     /locus_tag="VUX16_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124388.1"
                     /translation="MTKEMFVQFSKKAAVNEVMRKTGMSKKRAVKAVEELEREGVLFS
                     MGNGTVMMGV"
     gene            27537..28631
                     /locus_tag="VUX16_001443"
     CDS             27537..28631
                     /locus_tag="VUX16_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET8124389.1"
                     /translation="MADITVNQVATQTFYQIPQIFMVNVKKKFSAEGKPTGKIKMTSL
                     YAKKLSNDGKIAYGVLYDRCMLSIYSYRNGELTYVDENGSVFLVYTVEDLMEILDRSK
                     PTVLKIKKELKELGLLREVKQGKNRPNRLYLQNVNAELQEYEHYDAEVVEKGRDKGTV
                     VYHHVKTLDYKGCVLFEIERPGSEEESSILKDENSVLEKPIKSINSGSQKSLPPEVKN
                     FNPIKTEKSHTENNSTRHSSRKPASNSKELDQTAGTCDTPSQKTSGKKFIKPQVYSLL
                     QEIADSYRDHLPWYQHYNMTHRQKMIVGQYIQTGWITSSEVLHCIERIPECDSPFAYL
                     IQSIENLIGERKSEAKMQAHREAEYRYLSN"
     gene            28943..29257
                     /locus_tag="VUX16_001444"
     CDS             28943..29257
                     /locus_tag="VUX16_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124390.1"
                     /translation="MNQSKLVTEVTLADLRRLGNQGNATARLDNGDEIKLTSRYGLVP
                     KKGYLAGKLETVWMIVEYSKIYKEIRTIKRGDVLVVRRIKQGNTNRLLLTGKGYHRPT
                     KH"
     gene            29449..>30759
                     /locus_tag="VUX16_001445"
     CDS             29449..>30759
                     /locus_tag="VUX16_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HET8124391.1"
                     /translation="MKLRTTILATTASVTLLGLGNSQPVYANSTTSSQVESLKSEFIK
                     AKREYEQAKSIYDNALSSSPSNTIILSDKYIKALKTAFSDFNISQTERDSAKSILQSE
                     SLRLKNQNSFHKDVADEGERLDVNNLPLAVRQELSFFAQDLINQVRSQVGTPRVSVSI
                     SALDFADKVAKAYVQDNWGWHKMSVSGTLGHDATGINHVAREYGLPTTNSEEEKKGEQ
                     NYENLASRLPGFKTANKAQLKEAIYIGMIEFMFNDTEWMHAQSIAGLNWGNVNSKDYF
                     GLSFSSRSSVSSAHFITVSQEDIKRASKSSFSTAAVSDPTSVNRRQAIKKLEEDYKAK
                     EKIYQDFQKQADSKGSQGQSNQGSATVTEPSKPSAGSAEPTKSIENTSDLRDQWKQEG
                     SYWYYFDRAGKALVNSWKGNYYLKSNGVMARNEWVYDTNYKAWYY"
BASE COUNT         9635 a         5245 c         6928 g         8951 t
ORIGIN      
        1 aaaaataggc tccataatat ccatagggga tttacccact acaaatatta tagagcctct
       61 ttttcctatc aactcttttc tatttcctgt tattcatgtt ataatggata aatatgaaga
      121 aacggagtga gactataaaa tacagacgga ttgtctttaa ggttgggact tcttctctga
      181 caaatgagga tggaagttta tcacgtagta aggtaaaggc tatcacccag cagttggcta
      241 tgttgcacga gtctggtcat gaattgattt tggtgtcgtc aggtgccatt gcagctggtt
      301 ttggggtctt aggatttaaa aagcgtccga ctaagattac tgataaacag gcttcagcag
      361 cggtaggaca agggcttttg ttggaagaat acacgactaa tcttctcttg cgccaaatcg
      421 tttctgcaca aatcttgctg acccaggatg attttgtgga taagcgccgt tataaaaatg
      481 cccatcaggc tttgtcagtt ctacttagcc gtggggcaat tcctattatc aacgagaacg
      541 atagtgtcgt tattgatgag ctcaaggttg gggacaatga tactctgagt gcccaggtag
      601 cggccatggt ccaagctgac cttttggtcc tcttgacaga tgtagacggt ctctatactg
      661 gaaatcctaa ttcagaccca agagccaaac gcttggagcg aatcgagacc atcaatcgtg
      721 agattattga tatggctggt ggagctggtt cgtcaaacgg aactgggggc atgctaacaa
      781 aaattaaggc tgcaactatc gcgacggaat caggagttcc tgtttatatc tgctcatcct
      841 tgaaatcaga ttccatgatt gaggcggcag aggagaccga ggatggttct tactttgttg
      901 ctcaagagaa ggggcttcgt acccagaaac aatggcttgc cttctatgct cagagtcaag
      961 gttctatttg ggttgataaa ggggctgcgg aagctctctc tcaacatgga aagagtcttc
     1021 tcttatctgg tatcgttgaa gcagaaggag ccttttctta cggtgatatc gtgacagtat
     1081 ttgacaagga aagtggaaaa tcacttggaa aaggacgcgt gcaatttgga gcatctgctt
     1141 tggaggatat gttgcgttct caaaaagcca agggtgtctt gatttaccgt gacgactgga
     1201 tttccattac tcctgaaatc caactacttt ttacagaatt ttagaggtaa actatggtga
     1261 gtagacaaga acaatttgaa caggtacagg ctgttaaaaa atcgattaac acagctagtg
     1321 aagaagtgaa aaaccaagcc ttgctagcca tggctgatca cttagtggct gctactgagg
     1381 aaattttagc ggctaatgcc ctcgatatgg cagcggctaa ggggaaaatc tcagatgtga
     1441 tgttggatcg tctttatttg gatgcagatc gtatagaagc gatggcaaga ggaattcgtg
     1501 aagtggttgc cttaccagat ccaatcggtg aagttttaga aacaagtcag cttgaaaatg
     1561 gtttggttat cacaaaaaaa cgtgtagcta tgggtgtcat cggtattatc tatgaaagcc
     1621 gtccaaatgt gacgtctgat gcggctgctt tgactcttaa gagtggaaat gcggttgttc
     1681 ttcgtagtgg taaggatgcc tatcaaacaa cccatgccat tgtcacagtc ttgaagaagg
     1741 gcttggagac gactactatt catccaaatg tgattcaact ggtggaagat actagccgtg
     1801 aaagtagcta tgccatgatg aaggccaagg gttatctaga tcttctcatt cctcgtggag
     1861 gagctggctt gatcaatgca gtggttgaga atgcgattgt acctgttatc gagacaggga
     1921 ctgggattgt ccatgtctat gtggataagg atgcagacga agacaaggcg ctgtctatca
     1981 tcaacaatgc taaaaccagt cgtccttctg tttgtaatgc catggaggtt ctccttgttc
     2041 atgaagataa ggcagcaagc ttccttcctc gcttggatca aatgctggtt gcagagcgta
     2101 aggaagttgg actggaacca attcaattcc gcttggatag taaagcaagt cagtttgttt
     2161 caggtcaagt agctgaagca caagactttg acaccgagtt tttagactat gtcctagcgg
     2221 ttaaggttgt gagcagttta gaagaagcgg ttacccatat tgaaacccac agtacccatc
     2281 attcggatgc cattgtaacg gaaaatgctg aagctgcagc ttactttaca gatcaagtgg
     2341 actctgcagc ggtgtatgtt aatgcctcaa ctcgtttcac agatggagga caatttggtc
     2401 ttggttgtga aatggggatt tctactcaga aattgcacgc gcgtggtcca atgggcttga
     2461 aagagttgac cagctacaag tatgtggttg ctggtgatgg gcagataagg gagtaagaga
     2521 tgaagattgg atttatcggt ttggggaata tgggtgctag cttggcaaaa tctgtcttgc
     2581 agactaggac gtcagatgag cttctccttg ccaatcgtag tcaagccaag gtagatgctt
     2641 tcattgcaga ctttggtggt caggcttcca gcaatgaaga aatgtttgca gaagcagatg
     2701 tgatttttct aggagttaag cctgctcagt tttctgaact gctttctcaa taccagacca
     2761 tccttgaaaa aagagaaagt cttcttttga tttcgatggc agctggattg accttagaaa
     2821 aactagcaag tcttatccca agtcaacacc gaattattcg tatgatgccc aatacccctg
     2881 cttctatcgg gcaaggagtg attagttatg ccttgtctcc taattgccgg gctgaggaca
     2941 gtgagctctt ttgtcagctt ttagccaagg ctggtctctt ggttggatta ggagaaagct
     3001 taatcaatgc agcgacaggt cttgcaggtt gtggaccagc ctttgtctat ctctttattg
     3061 aggccttggc agatgcgggt gttcagacgg gattaccacg agaaacagcc ttgaaaatgg
     3121 cagcccaaac tgtggtagga gctgggcaat tggtcctaga aagccagcaa catcctggag
     3181 ttttgaaaga tcaagtttgt agtccaggcg gttcgactat tgccggcgta gcaagcctag
     3241 aagtgcatgc ttttcgagga acggtcatgg atgcagttca tcaagcatat aaacgaacac
     3301 aagaactagg tcaataagag gtagttttat ctgcctcttt tatggtggtt gatactcttc
     3361 gaaaatcaaa ttcaaactgc gtcagcttca ccttgccgta ctcaagtaca gcctgcggct
     3421 agcttcctag tttgctcttt aattttcatt gagtatgaaa tgagaagaca aaaagattgt
     3481 cacaaacccc tatttttttg atagaataga agtagtaaaa aagaaatgag ttagacatgt
     3541 caaaaggatt tttagtctct cttgagggac cagagggagc aggcaagacc agtgttttag
     3601 aggctctact actaatttta gaggaaaaag gagtagaggt gctgacgagc cgtgagccag
     3661 gcggtgtctt gattggggag aagattcggg aagtaatttt ggatccaagt catactcaga
     3721 tggatgcgaa gacagagttg cttctctata ttgccagtcg cagacagcac ttggtggaaa
     3781 aagttcttcc agcccttgaa gctggcaagc tggtcattat ggatcgtttt atcgatagtt
     3841 ctgttgccta tcagggattt ggtcgtggct tagatattga agccattgac tggctcaatc
     3901 agtttgcgac agatggcctc aaacccgatt tgacactcta ttttgacatc gaggtggaag
     3961 aaggactggc tcgtattgct gctaatagtg accgcgaggt taatcgtttg gatttggaag
     4021 ggttggactt gcataaaaaa gttcgtcaag gctacctttc tcttctggat aaagagggaa
     4081 atcgcattgt caagattgat gctagtctcc ctttggagca agttgtggaa actaccaagg
     4141 ctgtcttgtt tgacggaatg ggcttggcca aatgaaacaa gaacaattaa aggcttggca
     4201 accagcccag tttgaccgat ttgtccgtat cttagaacaa gaccagctca atcacgccta
     4261 tttcttttca ggtttctttg gaagcctgga aatggcgcag tttttggcca agagtctatt
     4321 ttgtacggat aaggtagatg ttttaccatg tgaaaactgc cgaaattgta agctgattga
     4381 acagggagag tttccagatg taaccttgat taagccagtc aatcaggtca tcaagacaga
     4441 acgcattcgg gaattggtgg gacagttttc tcaagcaggg attgaaagcc agcaacaggt
     4501 ctttatcatc gagcaagcgg ataaaatgca tcccaacgca gccaattctc tgcttaaggt
     4561 catcgaagaa ccccagagtg aagtttatat tttcttcttg actagcgatg aggaaaagat
     4621 gttaccgaca atccgaagtc ggacccagat tttccacttt aaaaagcaag aagaacaact
     4681 catcttgctc ttagaacaaa tgggacttgt taagaaaaaa gcgactcttt tagctcagtt
     4741 tagtcaatcg cgagctgaag cagaaaagtt ggctaatcag gcaagttttt ggaccttggt
     4801 cgatgaaagt gaacgcctgc tgacttggtt agtagctaag aaaaaagaaa gttatctaca
     4861 ggttgccaaa ttagcgaact tggcagatga taaggaaaaa caagatcagg ttttacgggt
     4921 tcttgaagtt ctctgtgggc aggacctctt gcaggtaaga gtaagggtga ttctacaaga
     4981 tttgctagaa gctagaaaaa tgtggcaagc taatgtcagc tttcaaaatg ccatggaata
     5041 tctggtcttg aaagaaatat aaactcaaaa atgaacgata aagaaaggaa aggcctggct
     5101 tatggacaaa aaagaattat ttgacgcgct ggatgatttt tcccaacagt tattggtaac
     5161 cttggccgat gtggaagcta tcaagaaaaa tctcaagagc ctagtagagg aaaatacagc
     5221 tcttcgtttg gaaaattcta agttgcgcga acgtttgggt gaggtggaag cagacgctcc
     5281 cgtcaaggcc aagcatgttc gcgaaagtgt tcgtcgcatt taccgtgatg gatttcacgt
     5341 atgtaatgat ttttatggac aacgtcgaga acaggacgag gaatgtatgt tctgtgacga
     5401 gttgttatac agggagtaag catgcagatt caaaaaagtt ttaaggggca gtctccctat
     5461 ggcaagctgt atctagtggc aacgccgatt ggcaatctag atgatatgac ctttcgcgct
     5521 atccagacct tgaaagaagt ggactggatt gctgctgagg atacgcgcaa tacaggtctt
     5581 ttgctcaagc attttgacat ttccaccaag cagatcagtt ttcatgagca caatgccaag
     5641 gaaaaaattc ctgatttgat tggtttcttg aaagtagggc aaagtattgc tcaggtctct
     5701 gatgccggtt tgcctagcat ttcagaccct ggtcatgatt tggttaaggc agctattgag
     5761 gaagaaattg cagttgtgac tgttccaggt gcctctgcag gaatttctgc cttgattgcc
     5821 agtggtttag ctccacagcc acatatcttt tacggttttt taccgagaaa atcaggtcag
     5881 cagaagcaat tttttgactc gaaaaaagat tatcctgaaa cacagatttt ctatgaatca
     5941 cctcatcgtg tagcagacac gttggaaaat atgttagaag tctacggtga ccgctccgtt
     6001 gtcttggtca gggaattgac caaaatctat gaagaatacc aaagaggtac aatttctgaa
     6061 ttgctggaaa gcatctctga aacgtctctc aagggtgaat gtcttctgat tgttgaaggt
     6121 gccagtcagg atgtggaaga aaaagacgag gaagacttgt tcttagaaat ccaagctcgt
     6181 atccagcaag gtatgaagaa aaatcaagct attaaggaag tagctaagat ttaccagtgg
     6241 aataagagtc aactctacgc agcctaccac gactgggaag aaaaacaata aagggagaca
     6301 ggatgtaata attctgtctg tttctgttta acttaattag tgatgataat attcggagtc
     6361 taaataatag aattgattga gtagtgaata aataaaaaca atgttcattc agtttacgtt
     6421 gaatatatat aatgtactct attagaatta tttttaagta cgcagtatgg tataattata
     6481 tatgagaaaa tagtgtggag tttatcagtt gaaaaaatat aacattgtag atttattttc
     6541 aggagcaggt ggtctatctt atggattcga gatggctgga tttaatgttc tattaggaat
     6601 tgataatgac gaaaaagcct tagaaacctt tcaaaaaaat catcagaatt cagaaatatt
     6661 atgtggagat attgcgaata tatcttatga ggaagatata aaaccaataa ttggagaaca
     6721 aaaaattgac ataattgtag gtggtccccc ttgtcagggg atgtcgcttt ctggacctag
     6781 aagatttgat gatccaagga acaaacttta tttgtcttat attcgattgg ttcgagaaat
     6841 acagccaact gcttttgtca ttgaaaatgt gattgggatt gttagtttgt ttaaagggca
     6901 aataaaagat actatcatag aagaattttc gaaaatgggt tataaggttc agtttaaagt
     6961 gttgctggcc tctgactatg gagttcctca aaatagaaaa cgtgttattt ttgtggggac
     7021 gaggaatgat ggatttgaat atcctgaagc attgggaaca atcattacaa cagagatggc
     7081 aatttctgat ttaccaacat tagaaaatga acttggcgag atagaaatgt cttatgtttc
     7141 agaaccacaa aatgactatc aaaaactaat gcgaaaacgt tcaaacgtag ttttgaacca
     7201 cgttgcagcc aagcattcag aaaaagtgat aagtacaatt gcccttgtcc ctgacggtgg
     7261 aaattataaa aatctcccga aggaattacg agaaacaaga aaatttaatg tcgcttggac
     7321 acgatttgct agttggaagc cagctcctac gattgatacg gggcatagac atcatttcca
     7381 ctataagtat aatcgtgtgc caacagtgag ggaatctgct cgtctacaat cttttccaga
     7441 tgattttatc ttttacggaa gtaaaacaca gcaatttaga caagttggta atgctgttcc
     7501 tcctttaatg gctcagcaga ttgcaaacaa tttactgaaa tatttaaaaa ataacgaaga
     7561 gtaactatgt atcaagttcc agagaaatat tattttagac tacatcaccc aagacctcgt
     7621 tttaaaaatg atgtcgaaaa tgtacttgtt tatatggcaa cgaatatttc ttatttggga
     7681 atattgccta aaaaggaatt tagtcagcaa ctaaatgaca ttatcaaaca atatgcagga
     7741 aatgcagata aaacagagaa aacaatcaat aactggcgaa cagagatttc ttctttgttt
     7801 ggaatgatga ttgagaaaga aggctttgtc tattcaggaa atagggctaa ggaattgact
     7861 gaagaccaag accttattcg cttttttaaa acctttttgt ataattttga atatcctggt
     7921 gggcatctaa aagataacga gattgttaaa ctttgtcaaa tcggagttca atttaagcca
     7981 gctcagtatc tactggaact atttacagaa gcctcacaag ctgaagaaaa aactatttac
     8041 ctcaccgatg aagaagtcgc ccattgtatc tttaatgatt tgagatgtac tcgtgataga
     8101 gagcctgttt tggaaatatg gaatcgtatc aaagagaata gagcgtctaa agtagcttac
     8161 gatactaaag gagatgttat tcgatatgcc aaagatgttt tagattacat ggttatagcg
     8221 agtttactaa ctgttcaagg tggtaggtat aaaataaatt ctatggaaga gcaagcaaca
     8281 aatgactttt tgcaatcaga tgctaccttt gatggctatg ctcaatttat tggaaatgct
     8341 tctacaacaa ttgaagatgt tcgaaatttt agaagtgctt ggttcgaata tgtcaatcgt
     8401 gatttaggag atattgattt taggacaaac tttaatctct accttccaag tgatattgat
     8461 tttactgaag agaaaacaga tattatcgga catctaactg aacacatcga atacagcgag
     8521 aaaatatcta ccgctgttgt agggagttcg ggagaagcta ttgttatcaa tcatgaaaaa
     8581 caaaaattac gagaacatgg gcaagaacag ttgctccatc tggtgaattt tattccaaca
     8641 cagtttggtg tcggctacga tgttcaatct tttgagtgtg atgattctga gctgagaaag
     8701 tatattgaag tcaaaacaac tgtcagcaat gcttctatta cttttaattc gtttcatatc
     8761 acaccaaacg aatggcgaac tgctaaatct gtgcgtgata gatactatat ttatcgtttg
     8821 cagatttcta aacatagcaa aaaattgttt attatcaaga atttgtatga gttagtcaaa
     8881 aatgagaaga tgcttctgat tgagagaaaa gatggatatg atgcccgttt ttcatcgtca
     8941 gttggctttg aggagaattt aatttgaaga aactaaaaat tgcctctctt tttagtggag
     9001 ggggtggaac ggatattggt tttgctggtg gatttgattt tttaggtaaa cattatgccg
     9061 acaatcaaat tgagattgtc tatgcaaatg atattgaaga cagtgccaat aaaatgtttg
     9121 aaaagaattt tggtgttact ccagacaatc gaaatatccg agaaataaaa tcagatgaaa
     9181 tcccatcttt cgatatttta acgggaggtt ttccttgtca atcattttct gttagtgctc
     9241 aaaatccgaa acgcttagga ataaaagacg aaaaagggac attgtttttt gagatggtgc
     9301 gagtgttaaa agctcatcaa ccaaaagcat tttttgccga aaatgttaag ggaattttgt
     9361 ctgcaaacaa taaagaagcc tttcctctaa ttattgaaga gttcgaaaaa gctggttata
     9421 atgtttctta taaactttgc gtagccacca aatacggcgt tccgcaaaag agagagcgtg
     9481 tgtttattgt tggtattcga aaggatttga attttacttt tgaatttcct gaagagccta
     9541 ttcaaaatgt agaagattat acaccactaa aagtaattct tcagcaagat attgatgaaa
     9601 agtattattt tagtgagagg gctgtgcaag gaatgctaaa tagtaaatct ggcaaaaaaa
     9661 tgaataaagg acgagcacaa gacattgaac agccgagtaa tacggttagt tctcacttag
     9721 caaaagtatc cttaaatagc actgaccctg ttttgttaga aaatggacgt taccgtcgct
     9781 atactccaag agaggttgca cgtattcagt cgtttccaga aaactatgaa ttgcttggtt
     9841 cagaaggtgc tcaatataga atgctgggga atgctattcc accagtaatg atgtggtata
     9901 ttgctgaaaa gttagtgtca gatttacgaa atagtgatgt aattgcaaag caacagaaac
     9961 tcgaagaaag ttttggtcaa ctggatttgt ttgaagcgag ttgatgtttt aaatctaggg
    10021 aacttgatat ggaattaaat tttcaagata agagttttat aaaagtattt tttaatagtg
    10081 acggttatgt attaaatttt tctaactcta cttttgctaa ttttactttt aattcagtag
    10141 gagtaaatat tcaagagaaa tatggaggtt caaaagggaa agctttacag gcttttgtag
    10201 ataacgaacc agatgaactg gttttaaaat tggctttaga tttacttaga tattatgaag
    10261 accttcctga ctcatattac gagaaaactg aagagaggaa ctctcaggca ttgaaattga
    10321 aagagagact ttcgaaatat gaagtctcac aaatagccta cttaaataat gctgctaaat
    10381 ctttatctga ctattttgat agcgactata tagataagca aatggggatt atgaatgaaa
    10441 tgatttctcg ctctccagcg gacgctattg gaaaagctaa ggaattgttg gaatcgtgtt
    10501 ttaaacatat tttagaccat gaaaaaattg agtattctaa ttctaatgat attgcaactt
    10561 tgcaaaagaa agtctttaaa tttttaaact tggattctaa tgaaaatatt tcagcaaaaa
    10621 ataatcaaga tgtgaaggtg gttctaagtg gtttgaatca aattatcaag ggtattaaca
    10681 atcttagaaa tgataaaggc gatggtcatg gtaagggagc taactttata gaattgccac
    10741 caaggtatgc ttcagttgtt gtaggttctg cattaacggt agtgtcattt gtttgggaaa
    10801 cataccaaga taagcaaaaa tagtaaagga gggagattta atgtcgaaaa atcaagaaaa
    10861 attacacttt caacttaaaa aatttatagt aaatgtaggt tggactcaca aaattcatgc
    10921 ggttagaatt gacgagttag aaagctatat tcgatggttt agaatagcaa caataatcat
    10981 ttctggagtt gtctcttctg gcttagttgg aatactttgg tttgatgaat attggataaa
    11041 gcttgttaca gcatttttat cattagtcac gacaataatt tttagcatca caaaggagtt
    11101 taactttgag gaacgactag ctttggagag gaaatctgtt gatgagcttt ggaatcttag
    11161 agtgttagct gaaattcttt tatctgaggt ggtttacaat ggaaaaccat ccagtgaaat
    11221 ccaagaattt ttcgaagaat taaaatttcg aagagatgct acttatagtc aactttctaa
    11281 tgcttctccc aaaaatgtat ccaaggcttc aaaactaata aaatcgagaa aagataatga
    11341 ttatgaggag gattatagat actttattcc aaaagaattg atggaaatta aggaggaaga
    11401 gtaatgtctt tatctaatga ttttaaagaa ttttgcgaag acgaactccc catgacggat
    11461 gaggaatggg aaaaatggga gaatagatta aaagagatta cgaaacgact taatcgaaaa
    11521 ttttattcct tagatgagct tgacgatcaa gaaactgaca acggtttgat tgttggtagt
    11581 gtggggagaa cgacggctgt tcgaaatgtt agtgattttg attatatttt ttctctacca
    11641 tcagaagtgt atagacgatt tgattcttat gagggcaatg gtcaatcagc actcctacag
    11701 gaaataaaaa acgaattact aaaaagatac ccaaatacaa aaataaaagg agacggacag
    11761 gtcgttgtta ttgatttttc ggatggtgga aaaattgagt tagttccagc tttcgaaaaa
    11821 tctgatggta attttaaata tcctgattct cgtaacggag gctcttggaa aactactaaa
    11881 ccaaagtttg aaattgaaaa atgcaaatct ttaaattcca attttaatag tcatttttct
    11941 aacttaacaa ggctcatacg acaatggaaa aatcatatgg gcttttcatt taaggggttg
    12001 ttgatagata ctttgatatc tgatttaatt gatgataaag gtatttctga aatatattat
    12061 tctgattata atattctctt gaaagatatt tttgaatact tttcaaatca agataaaaat
    12121 agagagtatt ggtatgcttt aggtagtaat caaaagattt ataataatga tggagcaaaa
    12181 tttgtcaata aagctaagca ggctctaaag aaaatagaag acgcttcaga agagaaactt
    12241 actgaagttt atagacagct atttggtaga aaattcgctc aatctacttc tacaacaaat
    12301 cgagcttcga atgaagaatt tattgatgaa ttgtttaatg ttaatatcga atataatatt
    12361 gttttggagt gtgaaattac acaagatggt tttcgaaaag cacttctttc agacttttta
    12421 aaaagtagat ttaagattaa aaatagaaaa tctcttgatt ttgaaattat aaaatcagat
    12481 attccagata atcttttgtc tgatgttaaa tattattgga aagtgagaaa tattggagct
    12541 gaggcgatta gaagaaattg tgagcgtggt gctatttttt caggtaaaat aaaacatcac
    12601 gaagattctc agtttaaagg agaccactat gttgaatgtt atgctgtttt agataatacg
    12661 gttatagcaa gagatagaat aacagtccct atcgatccgt tatgtggaaa agattttata
    12721 gagtagcata taattgattc ttaactggaa tactctctat ctctttacat caagaaaatg
    12781 actaaacagg gaagtttgcc ttcttccctt tttttgttat actagtagaa gaaaaaaata
    12841 gaaagatttg tgggagtgaa aaagtccggg ggactttttc agcttgagcc aagaaattcg
    12901 agagcgagga aagtctgggg gactttttca gcctgagcca agaaattcga gagcgaagta
    12961 agtccaatgg actttttcag cctgagccaa gaaactcgaa agctcgtaag tctgattggc
    13021 tttttcaatg tgaatcttaa cttcacactc ccaaagaggt attagtgtcg tgtctcaatc
    13081 ttatatcaat gttatcggtg ctggtttggc aggttctgaa gcagcttacc aaatcgcaga
    13141 gcgtggtatt ccagttaaac tttatgaaat gcgtggtgtc aagtcgactc ctcagcacaa
    13201 aacagacaat tttgctgagt tggtttgttc caattctttg cgtggggatg ctttgacaaa
    13261 tgcagttggt cttctcaagg aagaaatgcg tcgcttgggt tctgttatct tggaatctgc
    13321 tgaggctaca cgtgttcctg ccggtggagc ccttgcggtg gatcgtgatg gtttctctca
    13381 aatggtgacc gaaaaagtgg tcaaccaccc cttgattgaa gtggtgcgtg atgaaattac
    13441 agaattgcca acagatgtta ttacagttgt ggcgactggt cccttgacta gcgatgccct
    13501 ggctgaaaag attcatgccc ttaataatgg cgatggcttc tatttctacg atgcagcagc
    13561 gcctattatc gatgtcaaca ctatcgatat gagtaaggtc tatctcaaat ctcgttatga
    13621 taagggagaa gcagcctatc tcaatgctcc aatgaccaag caagagttta tggatttcca
    13681 tgaagccttg gtcaatgcgg aagaagcacc gctcaattct tttgaaaaag aaaagtactt
    13741 tgaaggatgt atgccaatcg aagttatggc caaacgtggc attaaaacta tgctttatgg
    13801 ccctatgaag ccagtcggtc ttgagtatcc ggacgactac acaggacctc gtgatggaga
    13861 atttaaaaca ccttatgcgg ttgtgcaact tcgtcaggat aatgcagctg gtagcctata
    13921 caatattgtt ggtttccaga cccacctcaa atggggagaa caaaagcgtg tcttccaaat
    13981 gattccgggt cttgaaaatg cggagtttgt ccgttatggt gtcatgcatc gcaattctta
    14041 catggattca ccaaatcttc ttgagcagac ttaccgttcc aagaaacaac caaatctctt
    14101 ctttgctggt cagatgacgg gggtggaagg ctatgttgag tcggcgactt cgggcttagt
    14161 tgcgggaatt aacgcagctc gtctcttcaa ggaagaaagc gaggttattt tccccgagac
    14221 gacagcgatt ggaagcttag ctcattacat tacccatgcc gacagcaaac atttccaacc
    14281 aatgaatgtc aattttggga tcatcaagga gttggaaggc gagcgtatcc gtgataagaa
    14341 ggctcgttat gaaaaaattg cagagcgtgc ccttgccgac ttagaggaat ttttgactgt
    14401 ctaatttttt tgaaagaatt gctcatgata ctataaaaat cttagaaatt gtgataaaat
    14461 aggtaggatg aaagaaggag agtgaaaatg gcgaatccca agtataaacg tattttaatc
    14521 aagttatcag gtgaagccct tgccggtgaa cgtggcgtag ggattgatat ccaaacagtt
    14581 caaacaatcg caaaagagat tcaagaagtt catagcttag gtatcgaaat tgcccttgtt
    14641 attggtggag gaaatctctg gcgtggagaa cctgcagcag aagcaggtat ggaccgtgtt
    14701 caggcagatt acactggaat gcttgggact gttatgaatg ctcttgtgat ggcagattca
    14761 ttgcaacaag ttggtgtcga tacgcgtgtg caaacagcca ttgctatgca acaagtggca
    14821 gaaccttacg tacgtggacg tgctcttcgc caccttgaaa aaggccgtat cgttatcttt
    14881 ggtgctggaa ttggttcacc ttacttctca accgatacaa cagcggctct tcgttcagct
    14941 gaaatcgaag cggatgccat tcttatggct aaaaatggtg tcgatggtgt ttacaatgcc
    15001 gatcctaaga aagataagac agctgttaag tttgaagaat tgacccaccg tgatgttatc
    15061 aacaaaggtc ttcgtatcat ggactcaaca gcttcaaccc tctcaatgga taacgacatt
    15121 gacttggttg tcttcaacat gaaccaacca ggcaacatca aacgtgtcgt atttggtgaa
    15181 aatatcggaa caacagtttc aaataatatc taagaaaagg aagaagaaag attatggcta
    15241 acgtaattat tgaaaaagct aaagagagaa tgacccagtc tcaccaatca cttgctcgtg
    15301 aatttggtgg tatccgtgct ggccgtgcca atgcaagctt gctcgaccgt gtacatgtag
    15361 aatactatgg agtcgaaact cctcttaacc aaatcgcttc aattacgatt ccagaagcgc
    15421 gtgttttgtt ggtaacacca tttgacaagt cttcattgaa agacatcgaa cgtgccttga
    15481 acgcttctga tcttggtatc acaccagcta atgacggttc tgtgattcgc ttgattatcc
    15541 cagttcttac agaagaaact cgtcgtgacc ttgctaaaga agtgaagaag gtcggcgaaa
    15601 atgctaaagt ggctgtccgc aatatccgtc gcgatgctat ggacgaagct aagaaacaag
    15661 aaaaagcaaa agaaatcact gaagacgaat tgaagactct tgaaaaagac attcaaaaag
    15721 taacagacga tgctgttaaa cacatcgacg atatgactgc caacaaagag aaagaacttt
    15781 tggaagtcta aaaataaaca gaaaaactca gttggcattg ctggctgagt tttattcgaa
    15841 agaaggaaat atgaatacaa atcttgcaag ttttatcgtt ggactgatca tcgatgaaaa
    15901 tgaccgtttt tactttgtgc aaaaggatgg tcaaacctat gctcttgcta aggaagaggg
    15961 ccaacataca gtaggggata cggtcaaagg ttttgcatac acggatatga agcaaaaact
    16021 ccgcctgaca accttagaag tgactgccac tcaggaccaa tttggttggg gacgtgtcac
    16081 agaggttcgt aaggacttgg gtgtctttgt ggatacaggc cttcctgaca aggaaatcgt
    16141 tgtgtcactc gatattctcc ctgagctcaa ggaactctgg cctaagaagg gcgaccaact
    16201 ctacatccgt cttgaagtgg ataagaaaga ccgtatctgg ggcctcttgg cttatcaaga
    16261 agacttccaa cgtctcgctc gtcctgctta caacaacatg cagaaccaaa actggccagc
    16321 cattgtttac cgtctcaagc tgtcaggaac ttttgtttac ctaccagaaa ataatatgct
    16381 tggttttatt catcctagcg agcgttacgc agagccacgt ttggggcaag tattagatgc
    16441 gcgcgttatt ggtttccgtg aagtggaccg cactctgaac ctctccctca aaccacgctc
    16501 ctttgaaatg ttggaaaacg atgctcagat gattttgact tatttggaaa gcaatggcgg
    16561 tttcatgacc ttaaatgata agtcatctcc agacgacatc aaggcaacct ttggcatttc
    16621 taaaggtcag ttcaagaaag ctttaggtgg tcttatgaag gctggtaaaa tcaagcaaga
    16681 ccagtttggg acagagttga tttagggaga tttatgagaa aatcatttta cacttggctc
    16741 atgaccgagc gcaatcctaa aagtaacagt cccaaagcta tcttggcaga cctagctttt
    16801 gaagaggcag cttttccaaa acacacagat gattttgatg aggtcagtcg ctttttggag
    16861 gagcatgcca gtttctcttt taacctagga gattttgaca gcatttggca ggaatatcta
    16921 gaacactagc atttattcat tgggtttgga ctagtaattt ctccatccct ctgctataat
    16981 aaaaagaaat aaaaggatta gagaggttct ttatttgaag gaacattcaa tagacattca
    17041 actgagtcat ccagatgacc tgtttcatct ttttggttcc aatgaacgcc atcttcgttt
    17101 gatggaagaa gagcttgatg ttgtgattca tgctcgtacg gagattgtcc aggttttggg
    17161 agaagagtct gcttgcgagg aagcccgtca ggttattcaa gctctcatgg ccttggtaaa
    17221 tcgtgggatg accgttggta cgccagatgt agtgacggct attagtatgg tcaaaaatga
    17281 tgaaatcgac aagtttgtcg ccctttacga agaagaaatc atcaaggaca atacagggaa
    17341 gcctatccga gtcaaaaccc tagggcaaaa gctttatgtg gacagtgtca aacagcatga
    17401 tgtgaccttt ggaattgggc cagcagggac ggggaagacc tttcttgcag ttattttggc
    17461 agtgactgcc cttaaacgtg ggcaagtcaa gcgaattatc ctaactcgtc cagcggtgga
    17521 agcgggagag agtcttggat ttcttccggg tgatcttaag gagaaggtgg atccttacct
    17581 tcgtcctgtt tacgatgcct tgtatcaaat tcttgggaaa gaccaaacga ctcgtctcat
    17641 ggagcgtgaa attatcgaaa ttgcgcccct tgcctatatg cgtggccgga ccttggatga
    17701 tgcctttgtc attctcgatg aggcgcaaaa cacgaccatc atgcagatga agatgttctt
    17761 gacgcgttta ggctttcatt ctaagatgat tgtcaatgga gatatcagtc agattgacct
    17821 gccacgtaat gtcaagtccg gtttgattga tgctcaagag aaactcaaga acatccatca
    17881 gattgacttt gttcattttt cagccaagga tgtggttcgc catccagttg tcgctcagat
    17941 tatccgagcc tatgaatatt ctactgaagt tgcacacgac tgattttgag gaagttcgcc
    18001 tgcaaaagaa tatactgttg agagaggaaa atccagttgt ataggctaaa ggttttatcc
    18061 aaaggtttga gacaacgatt aggcacgatg gaaagaactt ttatgtggct gatgacgatc
    18121 agtgcatctt cctgtgtcat aatcacaggg cacaagaaag taggaatttg aaaagatgat
    18181 tgaccaacta tctaagtatt acagttgtag gatactaact gaaaagaata ttccaagtat
    18241 tttatcttta tatgaaagta atcctctgta ttttcagcat tgtccaccag agccaaattt
    18301 tgcaactgta aaagaggaca tgctttgtct acctgaaggt aaagctaagg ctgataagtt
    18361 ttttattgga ttttggaatg gatctgacct tgtggctgtt atggattttg tctatgcaca
    18421 tcctgatgag gagactgttt ttattggttt gtttatggtt gatcaagcct atcagaggaa
    18481 agggattggt agtcatattg tgacagaagc actagcttat tttgctaaga actttcgaaa
    18541 ggcatgtttg gcttatgtta agggaaatcc gcaatctcag catttttggg aaaagcaggg
    18601 ctttaaatca attggatgcg aggttaagca agaactctat acggttgtta tcgttgaaca
    18661 gagcctagaa gattagaaat ggcatcaagt aagaactatt tggaatttgt tttggaacaa
    18721 ttatcaggat tagatgatgt gacttaccgt tccatgatgg gggagtatat tctttacttc
    18781 cgcggcaaga ttattgacgg catttatgac gatcgctttt tagttaaacc cgtgcaagca
    18841 gtcttagata agattgacca atcttctttt gagtttccat acaaaggtgc caaagaaatg
    18901 atttgagtgg aagaacttga taataagatg tttctataag acctgatttt agctatgtat
    18961 aaccaactgc caacgcccaa acctaaaaag aaaaagcaag ggtgaacgaa gtaaaaaaga
    19021 agtctgctaa ggccctgtct ttgcacgggt aaaattttat atataaaaag aagctgggac
    19081 taaagagctc agcttccttt ggtttatata attgtcatta caagacgaag tggttgggcg
    19141 aaactctgtt gactttattc aatttagagt ttcttatgca caattgagtc tggaacgaaa
    19201 gtctccagtt tcaaagtata cagtacaata aaccaacgat gtaatagctg atgacacaaa
    19261 gcacagtggg taggacttgt gaagtcaccc ttttcttttc aaaatttata ctaaatcatt
    19321 gatatcagtg tagtcacgat taagtccttg agcaactggt aggctagtca agtaaccttg
    19381 ataagtggtc acaccttgac gcaagccttc atcttcagag attgcttgtg cgaatccttt
    19441 gccagccaaa gcttcgatat aaggaagagt gacattggtt agggcgatgg ttgaagtgcg
    19501 ggtaaccgca ccagggatat tggcaacggc atagtggaga acaccgtgtt tttcatagac
    19561 gggttcatcg tgcgttgtca cacggtcagc tgtttcgata acgccacctt ggtcaacagc
    19621 aacgtcaacg atacagagcc tggacgcatt tgtttgacca tctcatctgt caccaattcc
    19681 ggtgcttttg caccagggat gagaatggct ccaatcacca catcagcatc tctcacactt
    19741 gcttcaatgt tgaatgaatt agacataaga gtttgaattt gacttccaaa gacttcttct
    19801 agaactgaga gacgcttggc actaatatct aaaatagtca cttgagcacc aagaccaagg
    19861 gcgatgcggg cagcatgtgt accgacgaca ccaccaccga tgatagttac ttttcctttt
    19921 ggaacacctg gtacaccacc aggtagaaca ccagagccac cagcttgctt agtaaggaag
    19981 tgagctccga tttgaacagc catacgacct gcaacctcac tcataggaac gaggagcggt
    20041 agttgtcctt gattgtcacg aacagtttca taggcaattc ctgttgtttt tgctgctaac
    20101 atagcatctg ctaattctgg agcagcggcc atgtgcaagt aggtgaagag aagaagatcg
    20161 tcgcgcaagt aaccgtattc agaacttaaa ggttctttta ctttcacaac caactctgct
    20221 gcccaagctt caccagcagt agcgacaatc tcagctcctt gcttttgata gtcagcatca
    20281 gtaaagccag aactgagacc agcatttgtt tcgataagga cacgatgacc acgactaact
    20341 aagctatgaa cacctgcagg tgtgagggcg acacggtttt cgttattttt aatttctttt
    20401 gggattccga ttaacattga gataacctac ctttcaattg acggtcttgt tttggttgtc
    20461 acattccagt tcataaatca aaaatgtgac ggtttcattg tatatgaaac cgcttcaaaa
    20521 atcaagaaaa acttgtcatc caaatttttt tatgctagac tagtgaaaat caagctctaa
    20581 tggagggaaa agtatggaat caatatttgt gaaatttgcc cagtatccgt ctatagaaac
    20641 ggagcgttta ttgcttagac ctgtaacttt ggatgatgcg gaagcaatgt ttgactatac
    20701 ctcggacaag ggtaatacac gttacacttt tccaaccaat caaatcttgg aagaaaccaa
    20761 gaataacatt gctcagttct acttggctaa tcccttggga cgttggggga ttgaattaaa
    20821 agataacggc aagtttatcg gaactattga cttacacaag attgaccctg ttcttaagaa
    20881 ggcagctatt ggctatatta tcaataaaaa gtattggaat caaggattga cgccagaaac
    20941 caatcgtgct gtgattgagc tagcttttga gaagatagga atgaataagt tagttgcttt
    21001 atacgataag gacaatcctg cgtcaggaaa ggtcatggag aaatcaggca tgcgtttttc
    21061 ccatgcagaa ccatatgctt gtatggacca gcatgaaaaa ggccgaatcg tgacaagagt
    21121 tcattatgtc ttgaccaagg aagactattt tgcaaataaa taagcagttg aaaagaaatt
    21181 ttcgactgtt ttttcttcct cttacgaata atctaagaga ggagaaaata tggaagcaat
    21241 tatcgagaaa atcaaagagt ataaaatcat cgtcatctgt actggtctgg gcttgcttgt
    21301 aggcggattt ttcctgctaa agccagctcc acaaacacct gtaaaggaaa cgaatttgca
    21361 ggctgaagtt gcagctgttt ccaaggattt ggtatccgaa aaggaagtga acaaggaaga
    21421 gaaggaagaa ccagttgaac aagatctaat cacagtagat gtcaaaggtg ctgtcaaatc
    21481 gccagggatt tatgacttgc ctgtaggtag tcgagtcaat gatgctgttc agaaggctgg
    21541 tggcttgaca gagcaagcag acagcaagtc gctcaatcta gctcagaaag ttagtgatga
    21601 ggctctggtt tacgttccta ctaagggaga agaagcagtt agtcaacaga ctggttcggg
    21661 gacagcttct tcaacaagca aggaaaagaa ggtcaatctc aacaaggcca gtctggaaga
    21721 actcaagcag gtcaagggac tgggaggaaa acgagctcag gacattattg accatcgtga
    21781 ggcaaatggc aagttcaagt cagtagacga gctcaagaag gtctctggca ttggtgccaa
    21841 gaccatagaa aaacttaaag actatgttac agtggattaa gaatttctct attcccctaa
    21901 tttacctgag ttttctgtta ctatggcttt actacgccat tttctcagta tcctattttg
    21961 ctttgttggg ttttgttttt ctgctagtct gcctctttat ccaatttcct tggaaatcag
    22021 caggtaaagt tctagtgatt tgtggagtct ttggcttctg gtttctgttt caaacttggc
    22081 aacagagtca agcgagtcaa aatctggcgg attctgttga aagggtacgg attttaccag
    22141 acactattaa ggtcaacggt gacagtctgt cctttcgtgg taagtctgat ggtcgtgctt
    22201 tccaagtcta ttataaactc cagtccgagg aggagaaaga agcctttcaa gctttaaccg
    22261 acctgcatga gataggacta gaagggaagc tttcggagcc agaagggcag agaaattttg
    22321 gtggctttaa ttaccaagcc tatctgaaga ctcagggaat ttaccagact ctcaatatca
    22381 aaacaatcca gtcacttcaa aagattggca gttgggatat aggagaaaac ttgtccagtt
    22441 tacgtcgaaa ggctgtggtt tggattaaga cgcactttcc agaccctatg cgcaattaca
    22501 tgacaggact cttgctggga catctggaca ccgactttga ggagatgaat gagctttatt
    22561 ccagtctagg aattatccac ctctttgccc tatctggcat gcaggtaggt tttttcatga
    22621 atggatttaa gaaacttctc ttgcgattgg gcttgaccca agaaaagttg aaatggttga
    22681 cttatccctt ttcccttatc tatgcgggac taactggatt ttcagcatcg gttattcgca
    22741 gtctcttgca aaagctactg gctcaacatg gggttaaggg cttggataat tttgccttga
    22801 cggtgcttgt cctctttatt gtcatgccaa actttttctt gacagcagga ggagtcttgt
    22861 cctgcgctta tgcttttatc ctgaccatga ccagcaaaga aggggagggg ctcaaggctg
    22921 ttgctagtga aagtctagtc atctccttgg gcatattgcc cattctatcc ttctattttg
    22981 cggaatttca accttggtct atccttttga cctttgtctt ttcctttcta tttgacttgg
    23041 tcttcttacc gctcttgtcc atcttatttg ccctttcctt tctctatcca gtcattcagc
    23101 tgaattttat ttttgaatgg ttggagggga tgattcgctt ggtatcacag gtggcaagta
    23161 ggcctctagt ctttggacaa cctaatgcgt ggcttttaat tttattgtta atttccttgg
    23221 ctttagtcta tgatttgagg aaaaacatta aaaggctagc agtgttgagc ttattgatta
    23281 caggtctctt tttcctgacc aagtatccac tggaaaatga aatcaccatg ctggatgttg
    23341 ggcaagggga aagtattttc ctacgggatg taactgggaa aaccattctc atagatgttg
    23401 gtggcaaggc agaatctgag aagaaaatcg aaaaatggca agaaaaggcg acgaccagca
    23461 atgctcagcg aaccttgata ccctatctta aaagtcgagg agtgagcaag attgaccagc
    23521 tgattttgac aaatacggac aaggagcata ttggagattt gttggaggtg accaaggctt
    23581 tccatgtagg cgaaatttta gtgtcaaaag gcagtctgaa acagaaggaa tttgtggtag
    23641 aactacaggc gactcaaaac aaagtacgta gtgtgtcagt gggagagaac cttctaattt
    23701 ttggaagtca gttagaagtc ctatccccaa ggaaaattgg agatggcggt catgatgata
    23761 ccctggttct gtatgggaaa ctcttggata agcaatttct cttcactgga aatttggagg
    23821 agaaaggaga gagagacttg ctgaggcaat atcctgacct agaagtggat gttttgaaag
    23881 ctagccaaca tggctctaaa acctcatcaa gttcagcgtt tttagaaaaa ctcaaaccag
    23941 agattaccct catctcagtt ggaaagagta atcggacgaa actcccccat caggaaacat
    24001 tgacacgact ggaaactatc aatagcaaag tttatcgaac tgatcagcaa ggagctatac
    24061 gctttaaggg gtggaaaagt tggaaaatcg aaagtgttcg ataggaagga caaatattat
    24121 atattagtaa aataaactaa aaatctgttg cataataatg ataaaaacga tataatgaaa
    24181 gcgtcttcga tattgatgat ataaaatcat taaaaatcag caaaagttgt tttattagct
    24241 agtttgttat ctattggtct ttttcagtcc agtgtatctg ctgtgagcgt tcttaaaact
    24301 tatcggtatg attggaatat cttctataag tctagtatga attatcacag acatagatat
    24361 agtgatattc cgtcatggtc tcgttattac agctattctg agtataaagt tggcggaggc
    24421 tggaactatg atcgttatga ggtaataaac tactacagcg gaggctatta atccttaaag
    24481 agtgataaaa aggagggcta ggtatgttgc agcttactca tgtgacctta aaaacgcgac
    24541 aagtcatctt acaagatgtt gattttacat ttgaaaaggg taggatttat ggtattcttg
    24601 ctatcaatgg ttctggaaag acgacactat tccgcaccat tagcaattta attcctataa
    24661 gtagcggaaa tattgcagcc cctccttctt tattttatta tgagagcgtt gaatggctgg
    24721 atggaagctt aagtgggata gactatcttc gccttatcaa aaacatctgg aagtcagacc
    24781 tgaacttgag ggatgaaatt gcctattggg aaatgtctga ctatatcagc cttcccattc
    24841 gcaagtattc cttaggcatg aagcaacgct tggtgattgc catgtatttc ctcagtcagg
    24901 ccaaatgctg gcttatggat gagattacaa atggcttaga tgagtattat cgacagaagt
    24961 tttttgatag gcttgcacaa atcgatagac aagagcagct ggttctttta agttcccact
    25021 ataaggaaga gttggttgat gtctgcgata gagtagtaac cattcatcag gggcagatag
    25081 aagaggttcc gttatgaaag atgttagtct atttttattg aaaaaagttt tcaaaagccg
    25141 cttaaactgg attgtcttac ttttatttgc atctgtactt ggtgttacct tttatttaaa
    25201 tagtcagact gcaaactccg tcagcttgga gagtaggttg gaaagtcgca ttgtggataa
    25261 cgggagagcc atcaatgaaa atgaagcgaa actttcccaa atgtctgaca ccagctcgga
    25321 ggaataccag tttgctaaaa ataatttaga cttgcaaaaa aatcttttga cgcgaaagac
    25381 agaaattctg actttattaa aagaagggcg ctggaaagag gcctattatc tgcagtggca
    25441 agatgaagag aagaattatg aatttgtatc aaatgacccg actgctagct ctggcttaaa
    25501 aatgggggtt gaccgcgaac ggaagattta ccaagccctg tatcccttga acataaaagc
    25561 acatactttg gagtttccga cccacgggat tgatcagatt gtctggattt tagaggttat
    25621 catcccaagc ttgtttgtgg ttgcgattat ttttatgcta acacaactat ttgcagaaag
    25681 atatcaaaat catctggaca cagctcactt atatcctgtt tcaaaagtga catttgcaat
    25741 atcctctctt ggagttggag tgggatatgt aactgtgctg tttatcggaa tctgtggctt
    25801 ttcttttcta gtgggaagtc tgataagtgg ttttggacag ttagattatc cctacccgat
    25861 ttatagctta gtgaatcaag aggtaactat tgggaaaata caagatgtat tatttcctgg
    25921 cttgctctta gctttcttag cctttatcgt cattgtggaa gttgtgtact tgattgctta
    25981 ctttttcaag caaaaaatgc ctgtcctctt tctttcactc attgggattg ttggcttatt
    26041 gtttggcatc caaaccattc agcctcttca aaggattgca catctgattc cctttactta
    26101 cttgcgttca gtggagattt tatctggaag attatctaag cagattgata atgtcgatct
    26161 aaattggagc atggggatgg tcttacttcc ttgcctgatt atccttttgt tagtggggat
    26221 tctatttatc gaaagctggg gaagttcacg taaaaaggaa gtttttaata ggtcttagct
    26281 ttcctatagg gaaaataagt aaaaactaac atagagaggg aatcaatttg attctctctt
    26341 tttgattcga aaaccaaacc aaaatacaaa cagaaacttt tcaaaaaaat aactgtaagt
    26401 gtctagagtt ttgagaaatg cagaaagaat ataaataaat gtagagaacg aaaaaatccg
    26461 ttctcttttt tcgttgccaa aaattaagga gaaaaaatgt cagataatat tgaaattgtt
    26521 atggatattg attcgctaga aattttcgat gtaatagatc ttgataagaa tgaaaatatg
    26581 gttgattgta tttctgaagg aaattctgat gaaaagtatc tccagacaat gaccttgcta
    26641 gagtttggct tggaaacgat tattataagc tcgctagtat tttatggaaa gtcataaaag
    26701 atgatgttat tcatgaatta tatcttagaa ttaagcttgg cacttatccg tatttcagaa
    26761 gagctagaga tggaacatgg ggaatgggga caaaccagcc aactgactta tgatgaaggc
    26821 ctgtagacga cgatggaatt tactcctgag ttacttgctt ctgtttgaaa cgagagaggc
    26881 cgagatagca tgacaagact agaaagagaa atgttgaatt attataagcg ttcactggag
    26941 ctatatgagg caagactaga agtcttaaga aaaccttaca aaaaagtgag gtacaactaa
    27001 tgagtgcaga acgtgatctt gtgagaaaga aaatcaagga atttaagttc aagataggcg
    27061 aattagaagg aacattggaa gggagttaat ccatgtggtt ggaaacaatc gtttgttttg
    27121 attgtgatta tgaggaaaaa tgggaagaag ataatatttt caagcctatt cattgtcctg
    27181 aatgtagaga tgtattagat gttgtagaaa gagattggtt aggtgaaaca atacttagaa
    27241 gcacagtgca gtgtgagcga tgtaactttt tatttgacca tttggatttt cagcttggtc
    27301 tatctgaatg tccgagttgc ttttcaaagg agctcaaatt agtgagacag aaaaaggaga
    27361 tagtagaatg actaaagaaa tgtttgtgca attttcaaaa aaagcagctg ttaacgaagt
    27421 gatgagaaaa acaggaatga gtaaaaaacg tgctgttaag gcggttgaag aattagagag
    27481 agaaggagtt ctgttctcta tgggaaatgg tactgtgatg atgggggtgt gataacatgg
    27541 ctgatattac agtaaatcaa gtggcaacac agaccttcta tcaaatccca caaattttca
    27601 tggtaaatgt taagaagaaa ttttctgctg aagggaaacc tactgggaaa atcaagatga
    27661 cgagtctcta tgccaagaaa ttatcaaatg atggcaaaat tgcttatggt gtactctatg
    27721 atcgatgtat gttgagtatt tattcttaca gaaacggtga actgacttat gttgatgaga
    27781 atggttcagt atttcttgtc tatacggttg aggacttaat ggaaatttta gatcgtagta
    27841 agccaactgt gttgaaaatc aagaaagaat tgaaagagct tggcttgctt cgtgaagtga
    27901 aacaagggaa gaatcgtccg aatcgtttgt atctgcaaaa tgtgaatgct gaattacaag
    27961 aatatgaaca ctatgatgct gaagtcgtag aaaaaggacg tgacaaagga actgtagtct
    28021 accaccatgt aaaaacttta gattacaaag gttgtgtctt atttgaaatt gaacgtccag
    28081 gcagtgaaga agaatcttct attttgaaag atgaaaactc tgttttagaa aagcctatca
    28141 aatcaataaa ttctggaagt caaaaatctt tacctccgga ggtaaaaaat tttaacccta
    28201 ttaagactga gaagagtcat actgagaata atagtactag acatagttct agaaagcctg
    28261 cttccaattc taaggaattg gatcagactg ctggaacttg tgacactcct tctcaaaaaa
    28321 caagtgggaa gaaatttatc aaacctcaag tctattctct cttgcaggaa attgcagata
    28381 gctaccgaga tcatttaccg tggtaccagc attataatat gactcaccgc caaaagatga
    28441 ttgttggcca atacattcag acaggatgga taacaagtag tgaggttctt cactgtatcg
    28501 aacggattcc tgaatgtgat agtccttttg cttacttgat tcaatctatt gaaaatttga
    28561 ttggcgaacg taagagcgag gccaagatgc aagctcatag agaagcagag tataggtatc
    28621 tgagtaacta agctatagat gacatgagac taaatctagc ttttttgacc tgagcaagtc
    28681 ataaaactac ttttgacctt tgaaaattga atatccccac tgtcctgatt agcggaacta
    28741 agcataaaaa gaagaacaag ggcggtgtgt aggctagaaa aggatatcta gtgctgttcc
    28801 accacgtaaa agcaggcaaa gcctaagctg aaggagtttg cggtttctag acttaaaacc
    28861 gtgtgtaaaa aatacagcag gtatgtacgt catacctcgg catggctgta aatcagcctt
    28921 gattcagtaa ggaggagata agatgaatca atcaaaatta gttacagagg tcactttagc
    28981 tgaccttaga cgcttaggaa atcaaggaaa tgcaaccgca agacttgata atggcgatga
    29041 aatcaaatta accagcagat atggtttggt acctaaaaaa ggatatttag caggtaaact
    29101 agaaacagtt tggatgattg tagaatattc aaaaatttat aaagaaattc gcaccatcaa
    29161 acgaggtgat gttttagtgg ttagacgcat taagcaagga aataccaatc gtttactgct
    29221 gactggtaaa ggatatcatc gtccaacgaa gcattaaaca gatagagcct catctatctg
    29281 tttcatcaag gagaggagat ttgaactgtt ttaaacgtcc tatctttgat taagcggata
    29341 gatgaatgaa aattaagaaa aaaattgaga acaacctcta aaaatggtaa aataaaagta
    29401 taaaataaat attttaagaa cgtttttaaa caaaaaggag ataagattat gaaattgaga
    29461 acaaccatct tggcaacaac tgctagcgta acgttgcttg ggttaggaaa tagtcaacct
    29521 gtgtatgcaa atagtacaac gagtagtcaa gtagagagct taaaaagtga atttattaaa
    29581 gcaaagagag aatatgaaca agctaaaagt atctatgaca atgctttatc atcttcacct
    29641 agcaatacga ttatactgag tgataagtat ataaaggctt tgaagacggc tttttctgat
    29701 tttaatatta gccagactga acgtgacagt gcgaaatcta ttttgcagtc agaaagtttg
    29761 agattaaaga atcaaaatag tttccacaaa gatgttgctg atgagggaga acgtctggat
    29821 gtcaacaatc taccgctagc tgttcgtcag gagttgtcat tttttgccca agatttaatt
    29881 aaccaagttc gttctcaggt tgggacacct agagtcagtg tttcaatttc ggcacttgac
    29941 tttgcagata aggtggcgaa agcatatgtt caagataact ggggttggca taaaatgagc
    30001 gtatctggta cacttggtca tgatgcgact ggaatcaatc atgtggcgag agaatatgga
    30061 ctgcctacaa ccaattctga agaagagaaa aaaggggagc aaaactatga aaatctagct
    30121 tctcgtctac ctggtttcaa aacagctaac aaggctcagt taaaagaggc tatctatatt
    30181 gggatgatag agtttatgtt caatgatact gagtggatgc atgctcagag tattgctggc
    30241 ttgaactggg gaaatgtgaa ctcaaaagat tattttgggc tttcattctc tagtcgttct
    30301 tctgttagtt cagcccattt tatcacggtt tcccaagaag atatcaagcg tgcaagcaaa
    30361 tcaagcttta gcacggctgc tgtgagtgat ccaactagtg tcaatcgccg tcaagcaatc
    30421 aaaaagctag aggaagacta caaagccaag gaaaaaattt atcaagattt tcaaaaacaa
    30481 gcagatagta aaggatctca agggcagtct aaccaaggtt cagctactgt gacagaacca
    30541 agtaaaccaa gcgctggctc agctgagcct actaaatcga ttgaaaacac atctgatttg
    30601 cgtgaccaat ggaaacaaga gggaagttat tggtattatt ttgatcgtgc agggaaagct
    30661 cttgttaata gttggaaggg aaactattat ctcaaatcaa atggtgtgat ggcacgtaat
    30721 gaatgggttt atgatacaaa ctataaagct tggtattat
//
LOCUS       DAVDZK010000028        30127 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVDZK010000028 DAVDZK010000000
VERSION     DAVDZK010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30127
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.029"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            89..2500
                     /locus_tag="VUX16_001446"
     CDS             89..2500
                     /locus_tag="VUX16_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET8124392.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLVKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKISTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            2750..3451
                     /locus_tag="VUX16_001447"
     CDS             2750..3451
                     /locus_tag="VUX16_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124393.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            3453..6161
                     /locus_tag="VUX16_001448"
     CDS             3453..6161
                     /locus_tag="VUX16_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET8124394.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALTTHLQDQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLRLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVATVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(6257..6748)
                     /gene="tpx"
                     /locus_tag="VUX16_001449"
     CDS             complement(6257..6748)
                     /gene="tpx"
                     /locus_tag="VUX16_001449"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET8124395.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(6871..7800)
                     /gene="psaA"
                     /locus_tag="VUX16_001450"
     CDS             complement(6871..7800)
                     /gene="psaA"
                     /locus_tag="VUX16_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET8124396.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(7832..8680)
                     /locus_tag="VUX16_001451"
     CDS             complement(7832..8680)
                     /locus_tag="VUX16_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET8124397.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(8677..9399)
                     /locus_tag="VUX16_001452"
     CDS             complement(8677..9399)
                     /locus_tag="VUX16_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET8124398.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            9690..11582
                     /gene="pepO"
                     /locus_tag="VUX16_001453"
     CDS             9690..11582
                     /gene="pepO"
                     /locus_tag="VUX16_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET8124399.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(11705..12334)
                     /locus_tag="VUX16_001454"
     CDS             complement(11705..12334)
                     /locus_tag="VUX16_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET8124400.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            13328..15550
                     /locus_tag="VUX16_001455"
     CDS             13328..15550
                     /locus_tag="VUX16_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET8124401.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            15580..16023
                     /locus_tag="VUX16_001456"
     CDS             15580..16023
                     /locus_tag="VUX16_001456"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET8124402.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(16290..16475)
                     /locus_tag="VUX16_001457"
     CDS             complement(16290..16475)
                     /locus_tag="VUX16_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124403.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRELTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(16494..16907)
                     /locus_tag="VUX16_001458"
     CDS             complement(16494..16907)
                     /locus_tag="VUX16_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124404.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGILTIDFLFFVLLAFISSQRFSSLMP
                     IITARHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            complement(17038..17684)
                     /locus_tag="VUX16_001459"
                     /pseudo
     CDS             complement(17038..17684)
                     /locus_tag="VUX16_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(17861..18511)
                     /locus_tag="VUX16_001460"
     CDS             complement(17861..18511)
                     /locus_tag="VUX16_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET8124405.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            18623..19465
                     /locus_tag="VUX16_001461"
     CDS             18623..19465
                     /locus_tag="VUX16_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET8124406.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            19541..19978
                     /locus_tag="VUX16_001462"
     CDS             19541..19978
                     /locus_tag="VUX16_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET8124407.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            20047..20349
                     /locus_tag="VUX16_001463"
     CDS             20047..20349
                     /locus_tag="VUX16_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124408.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYSGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(20440..21513)
                     /locus_tag="VUX16_001464"
     CDS             complement(20440..21513)
                     /locus_tag="VUX16_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET8124409.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFNWKIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            21669..22346
                     /locus_tag="VUX16_001465"
     CDS             21669..22346
                     /locus_tag="VUX16_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET8124410.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            22339..23313
                     /locus_tag="VUX16_001466"
     CDS             22339..23313
                     /locus_tag="VUX16_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET8124411.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(23362..25305)
                     /gene="thrS"
                     /locus_tag="VUX16_001467"
     CDS             complement(23362..25305)
                     /gene="thrS"
                     /locus_tag="VUX16_001467"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET8124412.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(25363..25539)
                     /locus_tag="VUX16_001468"
     CDS             complement(25363..25539)
                     /locus_tag="VUX16_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET8124413.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(25546..25686)
                     /locus_tag="VUX16_001469"
     CDS             complement(25546..25686)
                     /locus_tag="VUX16_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET8124414.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(25943..26317)
                     /locus_tag="VUX16_001470"
     CDS             complement(25943..26317)
                     /locus_tag="VUX16_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124415.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPLVILIISLLYSYRFRFSLWWLVGNGLLFYFTIITFGEFILIYLLIYETVALVSM
                     DSGISIKHILQKMKNKKLSQNP"
     gene            26556..27185
                     /locus_tag="VUX16_001471"
     CDS             26556..27185
                     /locus_tag="VUX16_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET8124416.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLFRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            27326..27595
                     /gene="rpsO"
                     /locus_tag="VUX16_001472"
     CDS             27326..27595
                     /gene="rpsO"
                     /locus_tag="VUX16_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET8124417.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            28409..29023
                     /locus_tag="VUX16_001473"
     CDS             28409..29023
                     /locus_tag="VUX16_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET8124418.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(29316..30065)
                     /locus_tag="VUX16_001474"
     CDS             complement(29316..30065)
                     /locus_tag="VUX16_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET8124419.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
BASE COUNT         8838 a         5627 c         6849 g         8813 t
ORIGIN      
        1 tttttttcta cacaaaatag gctccataat atccataggg ggttacccac tacaaatatt
       61 atagagcctt ttatgttagt atggaagtat gataaggaat aaaaaacaag attatgtact
      121 ggcctacaaa caaccagctt caaccactta catgggttgg gaagaagaag ctttaccgat
      181 aggcaatggt tctttaggag caaaagtatt tggccttata ggggctgaac ggattcaatt
      241 taatgaaaaa agtctctggt ctggaggtcc acttcctgat agttcagatt atcagggtgg
      301 aaatcttcag gatcagtatg tttttttagc tgagattcgg caggctttgg agaagagaga
      361 ttacaatctg gttaaggaac tggctgagca gcacctaatt gggccaaaaa cgagtcaata
      421 tgggacctat ctgtcttttg gggatattca cattgagttc agccagcaag gtacgacttt
      481 gtctcaggtg acggactatc agagacagct gaatattagt aaggcacttg cgacgacttc
      541 ttatgtctat aagggaacgc gatttgaacg taaagctttt gcgagttttc cagatgatct
      601 cttggttcaa tgttttacta aggaagggtt ggaaactcta gattttacta tagaactatc
      661 cttgacctgt gatttggctt ctgatggaaa gtatgaacag gaaaaatctg attacaagga
      721 gtgtaagttg gatattactg attctcatat cttgatgaag ggaagagtta aggataatga
      781 tctgcggttt gctagttatc tagcttggga aacggatgga gatattagag tttggtcaga
      841 tagggttcag atatcaggag ccagttatgc caatctcttc ttggccgcta agacggattt
      901 tgcccaaaat cctgctagca attatcgcaa gaaactagat ttagagcaac aggtgataga
      961 cttggtggac acagctaaag aaaagggcta tacccaattg aaatcaaggc atatcgagga
     1021 ctaccaagcc ttattccagc gtgttcaatt ggatttggaa gctgatgttg acgcatccac
     1081 tacagatgat ttgttaaaaa attataagcc acaagaaggg caggctttgg aggagctgtt
     1141 cttccagtat ggacggtatt tattgattag ttcgtccaga gactgcccag atgctctacc
     1201 agctaaccta cagggagtct ggaatgcggt cgacaatcct ccttggaatt cggactatca
     1261 cttaaatgtc aatctgcaga tgaattattg gccagcctat gttaccaatc tcctagagac
     1321 ggtctttcca gtcatcaact atgtagatga tttgcgtgtc tatggtcgtc tagcggctgt
     1381 aaagtatgca ggaatcgtct ctcagaaagg tgaggagaat ggttggttgg ttcatactca
     1441 agcgactccc tttggttgga cggcacctgg ttgggattac tattggggtt ggtcaccagc
     1501 tgccaatgcg tggatgatgc aaaccgttta tgaagcctat tcattttata gggaccaaga
     1561 ctatctcaga gagaaaattt atcccatgtt gagggaaacg gttcgttttt ggaatgcctt
     1621 tttacataag gatcagcagg cgcagcgttg ggtgtcttct ccgtcttatt ccccagaaca
     1681 tgggccgatt tcgattggca atacttatga ccaatctctg atttggcagt tatttcatga
     1741 ttttattcag gctgctcagg aattgggact ggatgaggac ttgttgactg aggttaagga
     1801 gaagtctgat ttactaaatc ctttgcaaat cactcaatct ggtcgaatca gggagtggta
     1861 tgaggaggaa gagcagtatt ttcaaaatga gaaagtggag gcccagcacc ggcacgcttc
     1921 ccatctagtg ggactctatc ctggcaatct ctttagctac aagggacaag agtatattga
     1981 agcggcacgt gctagcctca atgatcgtgg agatggcggc acaggctggt ccaaggctaa
     2041 taagatcaat ctctgggcgc gtttgggaga tggcaatcga gctcataaat tattggcaga
     2101 gcagttaaaa atatccacct tgccaaatct ttggtgtagc catcctcctt ttcagataga
     2161 tggtaatttt ggtgctacta gtggcatggc agaaatgtta ctccagtctc atgcagctta
     2221 tctggtacct ctagctgccc tacctgatgc ttggtcaaca ggttctgttt caggcttaat
     2281 ggcacgtgga cattttgaag tgagcatgag ctgggaagat aaaaaactct tacagttgac
     2341 cattttatca aggagtggag gagatttgcg agtttcttat ccagatattg agaagagtgt
     2401 gattaaaatg aatcaagaaa aaataaaagc gaaatgcatg gggaaagatt gtatttcggt
     2461 ggcaacagca gaaggtgatc ttgttcaatt ttatttttaa gaagatgtta taaggcagta
     2521 atttgaaact tccttttaat aaggatttaa gaatataggc agtttccaac tagttgaaaa
     2581 agcgttataa tgataatagg aagtaatact caatgaaaat caaagagcac aaactaggaa
     2641 gctagccgca ggttgctcaa aacagtgttt tgaggttgta gatggaagct gacgtggttt
     2701 gaagagagat tttcgaggag tataatttgt ttgatagagg gtggatctga tggcttatat
     2761 tgagatgaaa cactgttaca agcgttatca ggttggggac acggagattg tggccaatcg
     2821 tgatgtgaat tttgagattg aaaaggggga gctggttatt atccttggtg cttcaggtgc
     2881 aggcaagtca acagttctta accttcttgg gggaatggat accaatgatg aaggggaaat
     2941 ctggattgat ggtgttaata ttgcggatta tagttcccac cagcgcacca attaccgtag
     3001 aaatgatgtg gggtttgttt ttcagtttta taatctagtt tctaatctga cagctaagga
     3061 aaatgtggaa ctggcttctg aaattgtgac agatgccttg aatcctgatc aggtcttgac
     3121 agatgtaggt ctggctcatc gtctcaataa ctttccagcc cagctttctg gaggggagca
     3181 acagcgagtc tccattgcac gcgcggtagc caaaaatcct aaaattctcc tttgtgatga
     3241 accgactgga gccttggatt atcagacggg caagcaggtt ttgaaaattc tccaagacat
     3301 gtctcgtcaa aagggagcga cggtgatcat cgtgactcat aatggagctt tggcgcccat
     3361 tgctgatcgc gtgattcaaa tgcacgatgc cagtgtcaag gatgtggtgc tcaaccagca
     3421 tcctcaggat attgacagtt tggagtacta gcatgatcaa gcgaaaaact tattggaagg
     3481 acttaattca gtccttcaca ggctccaagg ggcgtttttt atccatcttg atcctgatga
     3541 tgttgggatc tctagcctta gtaggcctca aagtaaccag tcccaacatg gaggcgacag
     3601 ctaatgctta tttaacaact gctcaaacct tagatttggc agtcatgtct aactatggct
     3661 tggatcaagc agaccaagaa gaactaaaac agacggaggg cgcagaggtc gagtttggct
     3721 atttgacaga tgtgactatg gataatgggc aggatgccat tcggctgtac tccaaaccag
     3781 agcgaatttc aacctttcag ctaagaaagg gacgacttcc tcagtcagac aaggaaatcg
     3841 ctttgaccac tcatttgcaa gaccaataca gcgtgggaca ggagattagt tttaaagaaa
     3901 aagaagaggg tcattcctct ttaaaagacc atacttatac cattactggt tttgtggatt
     3961 cggctgaaat cctctcccag cgagatatgg gctacgcagg aagtggaagt gggactctga
     4021 cagcctatgg ggtgatttta cctagtcaat ttgatcagaa agtctacaat atagctcgtt
     4081 tgaaatatca agatttagca ggtttaaatg ccttttcatc agcttatgaa gaaaaatcca
     4141 agcaacatca ggaagagctt gaacaaattt tatcagataa tggcaaggta cgtctgcgac
     4201 ttttgaaaaa agaaggacaa gagtctctag acaaggggca agagaccctt gacaaggctc
     4261 agactaattt gcaggaaggc aagcgtcgtt tagcagctgc tcaagctcgt atacaggctc
     4321 aagaaagtca actagccttg tttcctcaag ctcagagaga acaggctagt gctcaactta
     4381 cccaagccaa gcaggaattg ggcaaggaag aggacaaact aaagcaagct gaacaaaatc
     4441 tagcccaaga aaaggaaaaa ttagaaaaac atcagcaagt cttggatgat ttggcggagc
     4501 caaggtatca ggtttataat cgtcagacca tgccaggtgg tcagggctat cttatgtata
     4561 gcaatgcttc atccagtatt cgagcagtgg gcaatatctt tcctgtggta ctttatgccg
     4621 tagcagccat ggtgaccttt acgaccatga ctcgctttgt agacgaagag cgaactcatg
     4681 cagggatttt taaggccttg ggttaccgta gtaaggatat tatcgccaag tttctccttt
     4741 atggactagt agctgggact gtcggaacgg ctctaggtag tatacttggt cattatttgc
     4801 tagccagtgt aatttcaagt gtcattacaa aaggcatggt ggtgggagaa acccagattc
     4861 agttctattg gacctatagc ttactagctc ttgtcttgag ctggttggcg agtgtgttac
     4921 cagcctatct ggtggcttgg agggaacttc atgccgaagc agcccagctt ctacttccta
     4981 aacctcctgt caaaggagct aaaatcttat tggagcgtat cggttttatc tggcgtcgtc
     5041 tcagttttac tcataaggta acagcccgca acatctttcg ttataagcag agaatgttga
     5101 tgacaatctt tggtgtggca ggttctgtag ctctgctctt tgcaggtttg ggaatccaat
     5161 cttctgtagc aggagttccg tctaaacagt ttcaacaaat ccaacagtat cagatgcttg
     5221 tctctgaaaa tcctagtgcg accaatcagg acaaggtaga gctagcagaa gtgttgaaag
     5281 ggcaggagat actagcctac cagaaaatct attctaaaac gctagacaag gatttcaaag
     5341 gcaaggctgg tcttcaaaac attactctta tgatgataga gaaggaagat ttgactccct
     5401 ttatccatct tcaacatcat cagcaggagc tgacattaaa agatggcatc gttattacag
     5461 ctaaactcgc ccagctggca ggtgtcaagg ttgggcagac tttagaaatt gaaggtaagg
     5521 aactaaaggt cgctgctatt actgagaact acgttggtca ctttatttat atgagtcagg
     5581 ctagctatga gcaactttac ggacagctac cccaagccaa cacttatctg gtctcattaa
     5641 gggataccag tgcaactagt atcgaaagtc aggcgggctt gcttatgaat caatctgcgg
     5701 tgtccagcgt tgtccaaaat gcttcagcca ttcgactctt cgactctatc gctagctcac
     5761 tcaatcagac catgaccatc ttggtcatcg tatcggttct attagctatt gtcatccttt
     5821 acaatctgac caatatcaac gtagctgaga gaatccgtga actctccact atcaaggttc
     5881 tcggttttca taataatgaa gtcaccctct acatttaccg tgagacgatt gtgctgtccc
     5941 ttgtgggaat cgtacttggt ctggtagctg gtttctattt acaccaattt ttgattcaaa
     6001 tgatttcgcc tgcgactatt ctcttttatc cgcaggtagg ctgggaagtc tatgtaatcc
     6061 cagtggcaac agtaagcatc attttgacct tgcttggttt cttcgtcaat tattatctga
     6121 gaaaggttga tatgttagaa gccctgaaat ctgtagagta aggtagttat ttttagctga
     6181 ttgaacttct atttactaat attcaaaaat cctctgtcac aaagagcagg gagctctttg
     6241 tgacagagga ttttttctat agggctttag cagctgcaat tgcggcttcg aagtttggct
     6301 cagaattgat attatccacg tattcaacgt agcgaatcgt attgtcagta tcgaggacaa
     6361 agactgcgcg tgctaatagg tgccattcgt tgatcaagag ggcataatcg cgcccgaaag
     6421 aatggtcaaa gtagtctgaa agcataatgg cattgtcaag gccttcagca ccgcaccaac
     6481 gtttttgagc aaaaggtagg tccattgaaa cagtcaatac gaccgtgttg tccagtccag
     6541 ccaattcttc attaaaacga cgtgtttgag ttgagcagat acctgtatcg atagaaggaa
     6601 cgacactcaa gacttttttc ttgccatcaa aatcagccag agatttttta gaaagatctg
     6661 ttgtagtaag agaaaaatca agcgccttgt cgccgacttg tagttgttta cctgtaaagc
     6721 tcacaggatt tccgagaaaa gttaccatag gatactccaa tcttttttct tccattgtat
     6781 ctaaaacagt cagaattttc caatgatttg accggaaatg tgtgcataga aaaaacgcca
     6841 gctcacatga gaatgacgtt tttcagaggc ttattttgcc aatccttcag caatcttgtc
     6901 aaggttgtat ttcatcatgc tgtagtagct gtcgccttct ttaccttgtt ctgcgataga
     6961 gtcagtaaag atttgtgcgt agattgggat gtttgtgtct tgagaaacag ttttcattgg
     7021 acggtcatcc acacttgatt ctacaaagag tgatggaact tttgtttggc gaagtttttc
     7081 aaccaaggtc ttgatttgtt caggagttcc ttcttcttca gtattgattt cccagatgta
     7141 ggcacttggg acaccatagg ctttagagaa gtatttgaat gctccttcgc tggttacaat
     7201 gagtttcttt tcagcaggga tcttattaaa tttatcctta ctttctttat caagtttgtc
     7261 taacttatca gtatattctt tgagattttt ttcatagaat tctttattgt tagggtcttt
     7321 ggcgctcaat tgtttggcga tatttttagc aaaaataata ccgttttcaa ggttaagcca
     7381 agcgtgtggg tcttcttttc ctttttcatt ttgaccttca aggtagataa catcaacgcc
     7441 gtcgctgact gcgaagtagt ctttgttttc agttttcttg gcattttcta ccaattttgt
     7501 aaaccaagca ttgccacctg tttcaaggtt gataccgtta tagaaaatca aatcagcctc
     7561 agaagttttc ttaacgtctt caggaagtgg ttcgtattcg tgtgggtctt gcccaatcgg
     7621 aacgatacta tgaaggtcaa ttttgtcacc agcaatattt ttagtaatat cagcgatgat
     7681 tgagtttgta gcaacaactt ttagtttttg accagaagtt gtatcttttt ttccgctagc
     7741 acatgctaca agaatgattg cagaaagaaa gagaacgagt aatgtaccta attttttcat
     7801 tagatcctcc aatttattag ggctttgccc cttattttaa caaatgttta tttttcagtt
     7861 tcaaatatcg ttgtttggga gcgataaaga agctaatgag aaagaaacta gcagctgtaa
     7921 gcacgatact agaacctgcc gcaacattaa aactatagcc aataaagagt cccaaaactg
     7981 aagcagtagc tccgaaggtt gaggaaagga aaatcatact tttcagacta ttagcataca
     8041 gataagcagt tgcagctggg gtaatcagca tggctacaat caggatagtt ccgacacttt
     8101 gcatggctgt cacagacacg agagtcagga gtaccatgag aaggtagtga tagaaattga
     8161 caggcattcc catggcttta gccaagagtt catcaaagga agttatcaag agttgcttga
     8221 agaaaatcca gattaacaag aggatggctg cccccacacc catagtaata aacatatccg
     8281 tatcttggac ggccaggata ttaccaaaaa ggatatggaa aaggtcagtt gaacttttag
     8341 cgacaccaat caagatgata ccgagggcta agaaagaaga aaaggtaatg ccgatggcgg
     8401 tatcgctttt gataatcgag tttcctttga tgtaggtaat gatgatggca gctagcaatc
     8461 caaagacaat ggctccgata aagaagtcaa ggcccaagat gaaggagagg gctacacctg
     8521 gtaagacagc atgtgaaatg gcatctccca tgagtgacat cccgcgtaga ataatgaaac
     8581 atcccacggc tccagctaca atcccgacga caatagctgt tatcaaggca ttttgtagga
     8641 aatggaattt ttgcaatcca tcgataaatt ctgcaatcat aggtcacctc cattgaaaaa
     8701 gagttgatta ccgtaagctt cttttagatt ggtttcggta aaagtttctt ttgttggacc
     8761 aaaggcaatc acttctcgat tgacaagtaa gacttgatcg aagtagtggg gaatcttgct
     8821 gaggtcgtgg tgaacgatga gaaccgtctt cccagctttt ttcaaatctc tcagcgtatt
     8881 catgatgatt tcctcactga cagagtcaat cccagcaaag ggttcatcca agaggatata
     8941 gtcggcttcc tgcaccaaac atctggcaat caagacccgc tggaattgac ctccagacag
     9001 ttgactaatt tgacgttcag cgtagtcagc taggccgacg atttcaaggg cctcttgcac
     9061 tttcttccaa tgtttagcct ttaaacttcg aaagagagga atagagggaa atagtcctaa
     9121 cgagacgcat tccttgacct tgatgggaaa gttgtagtcg atattgattt tttgttcgac
     9181 ataggcaatt cggtgtaagg attttttaac ttccttgtca tcgagaaatg cctgaccttg
     9241 atgtgggata attcccagca taccttttaa tagtgttgat ttcccagcgc cgtttggacc
     9301 aatgatgccg gtaattgttg gtccatggag cactagtgaa atatccttaa gtgccaacgt
     9361 ttctttgtag gagacactga ggttttcgat acgtatcata aacttgtatt cctcctgtct
     9421 cttaatatac attaaaaaaa aaattaagtc aagttaattt ttgaaaaaat taaaataata
     9481 actgaaaaat agattctaaa gataactttc aggataaatt tctaaattat aaaacgcata
     9541 gtatcaagtg taaaaaactt ggaattatgc gttttatcat ggaaagattt tttataatag
     9601 ctaaaaaata atagttaaat ggttattaat tgcattccct agtgattttt gttaagataa
     9661 atgcaaatac aaatgaaagc gagaacaaga tgacacgtta tcaagatgat ttttatgatg
     9721 ctatcaatgg agaatggcaa cagacagctg aaatcccagc agataagtct caaacaggag
     9781 gttttgttga tttagaccag gaaattgaag acctgatgct ggcgacaaca gacaagtggt
     9841 tagcaggtga agaagtgcct gaggatgcta tcttggaaaa ctttgtcaaa taccaccgcc
     9901 tagttcgtga ttttgacaag agagaagctg acggtatcac acctgtctta ccactcctta
     9961 aagaattcca agaattggag acttttgcgg attttacagc taaactagca gagtttgagc
    10021 ttgcaggaaa accaaacttc cttccttttg gtgtatcgcc agactttatg gatgctagaa
    10081 tcaatgttct atgggctagc gctccaagca caatcttgcc agatacgacc tactatgcag
    10141 aagaacatcc tcagcgcgaa gagctcttga ctctttggaa agaaagcagc gcaaatctcc
    10201 tcaaggctta tgatttctct gatgaagaaa ttgaagactt gctagaaaaa agacttgaat
    10261 tggaccgccg agttgcggca gtggtgctct ctaatgaaga aagttcagaa tatgctaaac
    10321 tctatcatcc atattcttac gaagatttca agaaattcgc gcctgcccta cctttggatg
    10381 acttcttcaa agcagttatt gggcaattac cagacaaggt tattgtagac gaggaacgtt
    10441 tctggcaagc agcagagcaa ttctacagtg aggaagcctg gtctctcctt aaagcaacct
    10501 tgattttgag tgttgtcaat ctttcaacca gctatttaac agaggatatc cgtgttttgt
    10561 ctggtgccta cagccgtgcc ctttctggag ttccagaggc aaaagataag gtcaaagcag
    10621 cttatcatct agcacaagaa cctttcaagc aagccctggg tctttggtac gcccgtgaga
    10681 agttctctcc agaagccaag gcggatgtgg agaaaaaagt ggcaaccatg attgatgttt
    10741 ataaggagcg tctgcttaag aatgactggc tcactccaga aacctgtaaa caggctatcg
    10801 tgaagctcaa tgtgatcaaa ccttatattg gctatccaga agaattgcct gcacgttaca
    10861 aggataaggt agtgaatgaa actgccagtc tttttgagaa tgctctagcc tttgcgcgtg
    10921 tggaaatcaa gcacagttgg agtaagtgga accagcctgt agactataag gaatggggca
    10981 tgcctgctca tatggtcaat gcctactaca atcctcagaa gaacctgatt gtctttccag
    11041 cagccatttt acaggcgcct ttctatgact tgcatcagtc atcttctgct aactacggtg
    11101 gtattggggc agtgattgcc catgaaattt cccacgcctt tgatactaac ggggcttcct
    11161 ttgacgaaaa tggtagcctc aaggattggt ggacagagag cgactatgct gccttcaagg
    11221 agaaaacaca aaaagtcatt gaccaatttg atggacagga ttcttatgga gcaaccatta
    11281 acggtaaatt gactgtatca gaaaacgtgg ctgacttggg aggaatcgca gcagcgcttg
    11341 aagcagctaa gagagaagca gacttctcag cagaagagtt cttctacaac ttcggtcgca
    11401 tctggcgcat gaaaggtcga ccagaattta tgaaactttt ggctagcgtc gatgtgcacg
    11461 caccagccaa actccgtgtc aatgtgcaag taccaaactt cgacgatttc tttacaacct
    11521 atgatgtcaa agaaggagac ggaatgtggc gttcaccaga ggagcgcgtg attatttggt
    11581 aatacaaaaa atctagtcat cagaaaaaag gcatccaatc acgtgtgaaa accttgatag
    11641 gatgcctttt gtaatagaaa gatttgctgg atagtttact taaatttcga ttgtcatcat
    11701 cttgctagaa aaagggattg aaggcctttt cgtgagcgat agtagtagct ggaccatgtc
    11761 ctggatagac atcgtagttt ggtagggtga agagttgggt ctggatacta tgaaggagtt
    11821 gctccatgct accagtcgga aggtcggtcc gtccgatagt ttcgcggaat agagcatctc
    11881 ccgtcaagac taggtgagca tcaggaaaga ctagggaaac accaccgata gagtgccctg
    11941 gggtcggtag aaccttaaaa cgaaattcct ctagttggta ttcttcgtga aagacaaagg
    12001 tgtgttctgc aggttttgtg accacatctg ccatatcatc gtggcgaggg agaccggaga
    12061 gattatcgac aggagtgtag agccagctgg cttcgctctc tgcgatatag acaggaggat
    12121 tgccaaacgt ctcgcgaacc aagtccagac tcatgatatg gtcataatgg gcgtgggtca
    12181 agagaatagc acagatcggt ttgttgatct tctcgattgt ctgacgaatg gcttcccaat
    12241 gactaccagg atcgacgacg atgaggtgct tttcgccttc tagataatag gtattttcat
    12301 aggcaacagg attcacggtt ttatggattt tcatactagc tccaatctca aagaatgtac
    12361 taatactctt cgaaaatctc ttcaaaccgc gtcaacttta tctgcaacct caaagcagtg
    12421 ctttgaacag cctgcggcta gctttctagt ttgctctttg attttcattg agtataaatt
    12481 aagtatagca cagttaggga gaataggtaa ggatttaaaa tgaacttaaa aaccagcatg
    12541 actagatgaa gacaggctgg ttatcaattt atcaatattg gaaaggtgtc aattgccctt
    12601 cataggttgc ataaactccg tcattagctt gtttgataga cgtgatgttt agagtgctac
    12661 cgtagttggc ttctcatttg tcgctatatt cactataagt tatcctactg ggcaggttct
    12721 ggtcgttagc atagtattga acgagttttt tatagctttg ctggctgaat aggaacaggc
    12781 agcaaactcc taacattagg agagcaaaga tagaaatagc agtttttttc ataggtattc
    12841 tccttataaa ctaaaggata gaagaaagta tcttgaggat ttttatactc ttcaaaaatc
    12901 tcttcaaacc gcgtcaacgt cgccttgccg tatatatgtg actgactttg tcagtcttat
    12961 ctacaacctc aaagcagtgc tttgagcaac ctgcggctag tttcctagtt tgctctttga
    13021 ttttcattga gtattaattc caaaatccag tcaaggtacc agtgtatgtg atacgagttc
    13081 caccgtttat ctttcgtatc ttcaatggaa ttggggaaat cagaaagtct ttgggttaca
    13141 atatggtttc cgttcttcta tctctccttc tatcacctaa gtttaaaatc taacttcgta
    13201 gtatattatg ggtcaataat tcagaattat caagcaattt tgaattattt ttttcttatt
    13261 ctgttccaat ctagttttca tattcttaaa aaagtgataa aatggtagga agaattggag
    13321 agtagagatg ccgaaagaag tgaatttaac aggcgaagaa gttgtcgctt taaccaaaga
    13381 atatttaacg gaagaggatg ttcattttgt ccataaggcc ttggtctatg ctgttgaatg
    13441 ccacagtggt caatatcgca aatcaggcga gccttatatc attcacccta tccaagtggc
    13501 aggtatttta gctaagctaa agctggatgc tgtaacagta gcttgtggat tcttgcatga
    13561 tgtggtggaa gatacagatg cgaccttgga cgatttggaa agagagtttg gtcctgatgt
    13621 gcgggtgatt gttgacggag ttaccaagct tggcaaggtc gagtacaaat cgatcgagga
    13681 gcaattagcg gaaaatcatc gcaagatgct catggccatg tctgaggata tccgcgttat
    13741 tttggtcaaa ctgtctgacc gcttgcacaa tatgcggacc ctgaaacatc ttcgaaaaga
    13801 caagcaggag cgtatttcca aagaaaccat ggaaatctat gccccacttg cccatcgttt
    13861 ggggatttcc agtgtcaaat gggaattaga agacttgtct ttccgttatc tcaatccaac
    13921 ggagttttac aagattaccc atatgatgaa ggaaaagcgc agggagcgtg aggccttggt
    13981 ggatgaggta gtcacaaaat tagaggagta tacgacagaa cgtcacttga aagggaagat
    14041 ttatggtcgt cccaagcata tttactcaat tttccgcaaa atgcaggaca agagaaaacg
    14101 gtttgaggaa atctatgatc tgattgctat tcgttgtatt ttagataccc aaagtgatgt
    14161 ttatgccatg cttggttacg tgcatgaatt ttggaaaccg atgccaggtc gcttcaaaga
    14221 ctatattgcc aaccgcaagg ccaatggtta tcagtctatc catacgactg tttatggacc
    14281 aaaagggccg attgaattcc agattcgaac caaggaaatg cacgaggtgg ctgagtatgg
    14341 ggttgcggct cactgggctt ataagaaagg tataaagggg caagttaaca gcaaggaatc
    14401 agctattgga atgaactgga tcaaggagat gatggagctc caagaccagg ctgatgatgc
    14461 taaggaattt gtggactctg ttaaggaaaa ctatctggct gaggagattt acgtttttac
    14521 cccagatgga gctgtccgtt cccttcccaa agattcagga ccgattgatt ttgcctacga
    14581 aatccatacc aaggtcggtg aaaaagcaac tggtgccaag gtcaatggcc gcatggttcc
    14641 actgacaacc aagttaaaga caggggatca ggttgaaatt atcgccaacc cgaactcctt
    14701 tggacctagc cgtgactggc tcaatatggt caagactagc aaggcgcgca ataagattcg
    14761 ccagttcttt aaaaaccaag ataaggaatt gtctgtcaac aagggtcgtg agatgctgat
    14821 ggctcagttc caagaaaatg gctatgtggc aaataaattt atggacaagc gccacatgga
    14881 tcaagttctg caaaagacca gttacaagac agaagactcc ctctttgcgg ccattggttt
    14941 tggggaaatc ggtgcgatta ccgtctttaa ccgtctgact gaaaaggaac gccgtgagga
    15001 agagcgtgcc aaggccaaag ctgaggcaga ggagcttgtc aaaggtggcg aggtcaaggt
    15061 tgaaaataaa gaaaccctca aggtcaagca tgagggggga gtggttattg aaggtgcttc
    15121 tggtctccta gtgcggattg ctaagtgttg taaccccgtg cctggtgacg atattgttgg
    15181 ctacattacc aagggtcgtg gtgtggctat tcaccgtgtg gactgtatga acctgcgtgc
    15241 ccaagaaaac tacgagcaac gtctccttga tgtggaatgg gaagaccagt actctagctc
    15301 aaataaggag tatatggccc atatcgatat ctacggtctc aaccgtacag gactgttgaa
    15361 cgatgtactg caagttcttt caaatacaac caagaatatt tcaacggtca atgcccaacc
    15421 aaccaaggat atgaagtttg ctaatatcca tgtgtccttc ggtattgcca acctctctac
    15481 actgaccacg gttgtcgata aaattaagag tgtgccagaa gtttactctg tcaaacggac
    15541 caacggctag ttgtcctagc tcttactaga aaggctatta tgaaaatcat tatccaacgg
    15601 gttaaaaaag cccaagtgag tatagaaggc cagattcagg gaaaaatcaa tcagggactt
    15661 ttattgctgg ttggtgttgg accagaggac caagaggaag atttggacta tgctgtgaga
    15721 aaactggtca atatgcggat tttttcagac gcagaaggca agatgaacct gtctgtcaaa
    15781 gatattgaag gagaaatcct ctctatttct cagtttaccc tctttgcgga tactaagaaa
    15841 ggcaatcgtc cagcctttac aggggcagct aaacctgata tggcatcaga cttctatgat
    15901 gctttcaatc aaaaattagc gcaagaagtg cccgttcaga caggcatctt tggagcagat
    15961 atgcaggttg agctggttaa taacggacct gttaccatta tcctagatac taaaaagaga
    16021 tgagaaagac caagcccagt cggcttggtc tttctcatct atcataaaat actccaaaaa
    16081 gaaatcggtt cttgatatgc ttgggggaag tctcttttca ggctttggca gatgcgatag
    16141 gaagggatga gatgtcctag gatgaggaga gttccctgaa ggaaaagtgg aatatcactt
    16201 aaagacacca aggagagaat catcaggcta tcccatagga gaatttgtaa agcaaaacgc
    16261 cagaatctcg gtctaatctg ggaatagagt taactaaagt ggtcacaaag ttggtttgaa
    16321 agataggtca atagcacagg atgaaagaaa atgagccaac cgctataaat caaaatccag
    16381 tcccaagtaa gctccctttt aaatgtcaaa aatgccagca tgattccatc aatgacaagg
    16441 agttgaatgg ttttgatgaa gatgattttt ttcatgctaa aacctccttt tccttagaga
    16501 cactcccata aagagatgtg tttgtcgtaa aagtctggat agttttctcc taggtagtca
    16561 gctgtcatat aataaaaagt agaatggcga gcagtgatga ttggcataag agatgaaaaa
    16621 cgctgagaac taatgaaggc taagagaaca aaaaatagaa aatcaatggt gagaatccct
    16681 aaatagtaga agcgaatctt tttattgatt tgaggataaa tctcagcgaa ttgatgtttg
    16741 agtcggacga ccaagagaaa tagcaggagt ccttgagcaa ggaagaaaat taaaccagag
    16801 agcaagagcc actcaaaaga tgtctcgagt ctagtgataa aaaatgcaaa tagtagcaaa
    16861 tcaataactg caattgctat aaaatggatt ctatagagtt ttttcatgac aagacctccc
    16921 tcttttatct aacttcattc tactctaaaa gaatgggagt tacaactaaa atgataaaaa
    16981 tagcagaggg gagattctct taagttgact agtattcttt atttgagttt ccttctatta
    17041 tctaacttct tcatcattcc agacaaataa agctccgatt gcattgagga tataaaagat
    17101 gtatttaccg atattggcga agtttccttg aataccagct tttgtcagct gaacgaaatt
    17161 gtaaatcaac caaaagcccc actgtccctc attgcaaatg cattcaaagc attggcaatg
    17221 agggacagtg caaaggcaat agttgttacg taggcaagga gattcatctt gcccccatat
    17281 ccgatatagt tggtcacaaa ggcaaagagg aaggcgatga tggaaatgat gatggccgcc
    17341 aattttacct gtttttggct catttggttg ggtctgcctt cttgcgaagc tttccatttc
    17401 tttatagcaa aggtataaat gaggaaggtg acgggatagg taatgatggc cgccttattt
    17461 ccaaggatat aatcaatagc accggacaaa atggtattaa caataccaaa gtaatttccc
    17521 catttgctta atttccccgt gaaacgagtg gacaacatgg aaatcccaac gttggttacg
    17581 gaaatcaatc caaagggtac aagagctgtc catagtcccc agtctacaaa tttatcgagg
    17641 cgtgagttga gataaccaga tgcaatcgca atcccaacga ccaaagcaac cccgaagagg
    17701 tcaaatcatt tagatgtagc aaaaattttt agtgattttt tcataggtta aactaccttt
    17761 ctttttttca aatactctac caccaaatga aagtaaaatc aaatgataga aataaaaccc
    17821 tgaaaataaa actttcaggg ttggtaggga acttgagaaa ttagttgatt ttctcgacat
    17881 agagttgttt tgcaatgtcc atattcactt gtaaatcctc gtcgttactg aggatagtga
    17941 aggtattgct gaagccatca aactgcttga cttggagctg gtcaccgatg tgaagtgagt
    18001 gcttgtccag ataatggaga atgtcaaaac tatcgtgcac ccgagtcagg cggtaggcgc
    18061 cagcttcctt gatatcagct agtgggaggt tattgatttc aacgaggagt tctcccttgg
    18121 caggaatagt tcctccgtgg gggcaggttt tagggaaacc tagcagttta tctagtcttt
    18181 ccacgaacag gtcagagaca gtgtgttcca agacctcagc ttcctcgtga atctggtcac
    18241 ttgtatagtc taaatgatga actagaaaaa cttcaatcaa gcggtgctta cgatagagct
    18301 cagagaccag tttgagaccg aggtcagtca gtagatagcc acattccttg tcctttagga
    18361 tgagattttc acttttcatt cgtttgatca tttcagttac ggcaggggga gagacttgca
    18421 tgcgagccgc aatttccttg ttggtaatct tatgcaggtc tatgccaatt tcataaatac
    18481 attttagata atcttctttg tttggggtca ttcgtttcct cttgtctaat atctttatct
    18541 agtatatcaa aaaaagctag atttctctag ctgtgacttt ttatgttata cttattgcaa
    18601 gagaaaaaac gaggagatgg atatgacgaa aatagctctt ctttcagata ttcatggaaa
    18661 taccaccgcc ttggaggctg ttttggcaga tgctcagcag ctaggagtgg atgaatactg
    18721 gcttttggga gatattctca tgccagggac aggacgtaga aggattttgg acttgttgga
    18781 tcaactaccg attacggcta gagttttggg aaactgggaa gacagtcttt ggcatggtgt
    18841 ccgtaaggaa ttggacagta ctcgccccag tcaacgctat ctcttgcgcc agtgccagta
    18901 tgttttagag gaaatttccc tagaagaaat tgaagtgctc cacaatcaac ctcttcaaat
    18961 tcatcgtcag tttggggatt tgacggtggg aattagccat catctgcctg ataagaactg
    19021 ggggcgagag ttgattcata ctggcaaaca agaggagttt gaccgcttgg tgactcatcc
    19081 tccctgtgat attgctgttt atggacatat tcaccagcag ttgcttcgtt acgggactgg
    19141 tgggcaattg attgtcaatc cgggttcgat tggccaacct ttctttttgg acgctcagct
    19201 acggaaggac ttgcgggccc agtatatgat tttggagttt gatgacaaag gcctggtaga
    19261 tatggacttc cgacgggtag actacgatgt ggcagcggaa ttgcagctgg ctaaagacct
    19321 gagacttccc tattttgagg tttactatga aagtctggtc aatgggatcc accatactca
    19381 tcatcaggaa tttttgagag aattggctca gaaagagggc tgcgatcggg agttagacga
    19441 ctggttgaaa agtggtaacg attgacatta caactaaaaa gggtataata atagaaaaag
    19501 aagagtagag gcagggtagc ctcgtaaaaa ggagaagagg atgcaaattc caagtagatt
    19561 taccattgca actcatatgc tgataatcat tgccctcgag gggaaggaaa gcaaggtgac
    19621 cagtgatttt ctggctgcta gtgttggggt caatcctgtc attatcagaa agatcttgtc
    19681 ccagttgaag aaggcagagc tgatttcagt agcgcgtgga acgggcggaa cagagattgt
    19741 caaggacctt aaggatatta gtcttttaga tgtttatcag gcggtcgaat gtcttggtaa
    19801 gacaggtcaa ctcttcagtt tccatgacaa tccgaatcca aattgccctg taggagctca
    19861 tattcatgat gttttggatc aaaaattgga gagaattcag ttgactatgg aggcagaact
    19921 tggtcagacc agtctagaaa aagtcgtggc cgatgcagag agtcagatga aggattaaga
    19981 gggataaatg ccctcttttt ttctttggat aattatgata aaatgtagct attaaaggag
    20041 taagaaatgt atctcgttat agaaattgta ttagccttta tagtgtcatt ttggaaggat
    20101 aatagaagtt tgtggaatcc agtattattt ttattatccc tcatttcaag ttatttttat
    20161 ctatcctacc ttttttataa aaatggatac gagaatgttc agttagcttt ttatgtattt
    20221 gcctttgtct tacttccttt tttgcttttt ctaagtggca tctttttaat ctatagtggg
    20281 gtcattttgt tgaaacgaga gggacgttcc aagccccatt atctctcaat gctctttgat
    20341 ttttattgac tattagattc tatttaaaaa gacttagaat gcacatgaaa gtatgtattc
    20401 taggtctttt gttttgtata catttaattt tcaagagtat tatctatttt tccatgcatg
    20461 gtaacgagta tcaatcaata actgggtaag gcgacccaag gtttctcttt cttctggagt
    20521 gagggattga gcttggacaa agagatgatg aatgtattca agcgccttta aggaagccaa
    20581 gtcattgata gagctaatac cagcatcaag aatagtgcca aagaagaggt cgaagtagag
    20641 ctgaagttct tcgtcaggga ctgtggccac ccattcttta aaggttgtgt ctacttgccg
    20701 gctatcactg ttggtcttat ccagttgaac gaagtgcttg tcctcaatct tccaattaaa
    20761 ggtatcgtgc tgggcgatgc cacccagggc agtactctga acgatgattt ggtgagcagg
    20821 aatttccagc atcataccga taatggaacc ttgtggaatg aatatcttgc ttctatccat
    20881 tatcctttga taacccgcag tctgtgtcaa ttcttgatgg agaccaggtg catcaaatgt
    20941 ataaactgct gtgatctgat tttgcaaact ttgctcaatt tggctagcag catagatagc
    21001 gagatttcct cccttggaat gcccagccag aataaccttt tgcttaggat gatgggcaaa
    21061 aaagttcttt aaatagcgaa gggcgtgctt ttgagcagga atttccttca tataggtcag
    21121 gtggaaatct tccttccagc caatgatact gtcatctgtc ccacgaaaga caatcagata
    21181 ggtatcgagg ctgacacgat aagtcatagc cgcaaattgc ttttgcagtt cagggtcgat
    21241 gtcgttgata aaatgggaga gtttgcaatt tttgaagcgc ttgtgttgag ccaattcatc
    21301 taataattga aggcgatttt tgctagtaag catggtgggc tctcttggaa cctgaggtgc
    21361 tagatctaaa agacgttgag gaagtgtgga gaccagatta tcaaaggaga ggtaggtgat
    21421 ttctattaag gttagaatgt ctaactcatt caagggaagg tcgtaataag aatcatatgc
    21481 gacatctttc agatagtcaa aaatattggc cataagagct cctttctttt tatttatctt
    21541 agcaaatttc cctcaaatta gctagtagca ttgcctgttt gtactggcta aaaacaggct
    21601 atttcaaatt cagtttcaga ccatctggca tggaaaaatc tgttataata atggaaaagg
    21661 agaagcgcat gcacaagatt ttattaatag aagatgatca ggtcattcgt caacagattg
    21721 ggaaaatgct ctctgaatgg ggatttgaag tggtcctggt agaagacttt atggaagttt
    21781 tgagtctatt tgttcagtcg gaacctcatc tggtcctcat ggatattggt ttgcccttgt
    21841 ttaatggtta tcactggtgt caggaaatcc gcaagatttc caaggtacct atcatgtttc
    21901 tttcttcgag agaccaggct atggatattg tcatggcaat caatatgggg gcggatgact
    21961 ttgtgaccaa gccttttgac cagcaggttc ttttagctaa ggttcagggc ttgttgcgtc
    22021 gttcctatga gtttgggcgt gatgagagtt tgctggaata tgctggtgtt atcctcaata
    22081 ccaaatccat ggatttacat tatcaagggc aagtcttgaa tttgaccaag aatgaattcc
    22141 agattttacg cgtgttattt gagcatgcag gcaacatcgt agcacgtgac gacctgatgc
    22201 gggaactttg gaacagtgac tttttcattg atgataatac cctctctgtc aatgtggctc
    22261 gtttgcgtaa aaagttggag gagcagggat tggtaggatt tatcgagacc aagaaaggaa
    22321 tagggtacgg attgaagcat gcttgattgg aaacaatttt ttctagccta tctgcgctcc
    22381 cgtagtcgtc tttttatcta tctgctttct ttggcatttc ttgtcttact ctttcagttt
    22441 ttatttgcca gtctaggaat ttacttcctc tactttttct tcttgtgttg ctttgtaacc
    22501 atcttatttt tcacttggga catattggtg gaaacgcagg tctatcgcca ggaacttctc
    22561 tatggagaga gggaagccaa gtctcctttg gaaatagctt tagcagaaaa attagaagcg
    22621 cgtgagatgg aactctatca gcagaggtca aaagcagaaa gaaaactgac ggatttgctg
    22681 gattactata ccttgtgggt ccatcagata aagaccccca ttgcagccag tcaactctta
    22741 gttgcagaag tggtcgaccg ccaactgaag cagcagctag aacaggaaat tttcaaaatc
    22801 gactcctata ccaacctagt tttacagtac ctgcgtttag aaagtttcca tgatgatttg
    22861 ctcttaaagc aggttcaaat tgaggacttg gtcaaggaaa taattcgtaa atatgctctt
    22921 ttctttattc aaaaaggctt aaatgtcaat ctacatgacc ttgataaaga aatcgtgacg
    22981 gataaaaaat ggctgctagt ggttattgag caaatcatct caaacagtct caagtacacc
    23041 aaggaaggtg gtctggagat ttatatggat gaccaagagc tttgtatcaa agatacggga
    23101 atcgggataa aaaacagtga tgtcctccga gtatttgaac gtggcttttc aggatacaat
    23161 ggccgtttga cccagcagtc ctctggactt ggcctttatc tatctaagaa aatttctgaa
    23221 gaactggggc accagattcg tatcgagtct gaggtcggaa aaggaacgac agtgcggatt
    23281 cagtttgctc aagtgaactt agtccttgag taaaaataga tgagaaaaag cctccagatt
    23341 ggaggctttt atgctagact cttatttctc aacgcgtgat ttgttggcga tatcagctag
    23401 gatagcttga acaaaattat caactgagac agtttgtgtt tctttttggc cgtagcgacg
    23461 aacgttgact gtttcgtctt ccatttcttt gtctccaaca attaattggt aaggaatctt
    23521 gctggtttgt gaagcacgga tcttgaactg cattttttca ttgcgctcat ctacgtctgc
    23581 acggacaccg cggtcacgga gtttcttggc cacttcccaa gcgtagtcca cgtgtttttc
    23641 gttagatact gggatgaggg ttacttggtg tggtgccagc catgttggga aggccccctt
    23701 gtagttctca atcaagatag ctgtgaagcg ttccatagtt gagataaccc cacggtggat
    23761 catgactgga cggtgatctt cgccatcagc tccgatgtat ttgaggtcga agcgttctgg
    23821 caacaagaaa tcaagttgga tagtagaaag ggtttcttct tttccaaggg cagttttaat
    23881 ctggatatcc aattttggtc cgtagaaggc tgcttcacct tcggcttcaa agtagtccac
    23941 gcccatttca tcaagagctg cacgaagcat ggtttgggca ttttcccaca tctcatcgtt
    24001 atcaaagtac ttatgagtat cttgagggtc acgaagagag aggcggaagc ggtagtcagt
    24061 caagttgaag tcttcataaa catcgataat caactgaagg gcacgttgga attcttcttg
    24121 gatttgttct ggagtaacga ataggtgacc gtcgttgagt gacatttcac gtacacgttg
    24181 aaggccagtg agggcaccag atttttcgta acggtgcatc ataccgattt cagcgatacg
    24241 gattggcaat tcacggtaag agtgaacatg gtgtttgaaa acttggatgt ggtgcggaca
    24301 gttcattgga cgaaggacaa attcttcccc gtcacccatg tccatggttg ggaacatgtc
    24361 ttcttggtaa tgatcccagt gaccagaagt cttgtaaagc tcaacagaag caagtggtgg
    24421 agtgtagacg tgttggtagc cagaagccaa ctctttgttt acgatgtagc gttccaattc
    24481 acgacggata gtcgcaccat ttggcaacca gaacggcaaa ccttgtccca cttcttgtga
    24541 aatcataaag aggtcaagct ctttaccaag tttacggtgg tcacgttcct tagcttcttc
    24601 acgcatttga aggtagtttt tcaagtcttt cttgtcaaac caagctgtac cgtagatacg
    24661 ttgcatcata gcgttgtcgc tgtttccacg ccagtacgca ccagctacat ggagaaggtg
    24721 gaagatttgg atacgacctg ttgatggaac gtgaggtcca cggcagaggt ctacatattc
    24781 accctgacga tagatagtca aaccgccttc gtcttctgag tgttcttcaa tcaattccaa
    24841 cttgtaaggg tcatttttga agatttcacg tgcctcgtct ttagtcactt cttcacgaat
    24901 agatgggaag ttttctttga cgattttttg catttcttct tcgatacgag gaaggtcttc
    24961 gttagagatt tgaccagctg tgttgtcagt atcgtagtag aaaccatctt cgatggctgg
    25021 accaactccc aagtgaatgt ccgggaaaag acgacgagct gcttgggcga acaagtgagc
    25081 tgctgagtga cgcaagattg gaagggcatc ttcgtgatca ggtgtcacaa tttcgatgct
    25141 tccatcttca gtgatagcgc gagtagtgtc gatgagtttg ccgttgaatt taccagccaa
    25201 ggctttttta gctagggaat tgctgataga ttgggcaatt tcaaaagttg ttacgccaga
    25261 ttcgaattca cgaacagcgc catctgggaa agtaatgtta atcatgatgt tctccttttt
    25321 tattatttca tagtttctaa gcattgattt tttatcagca gactacttcc gagtcctaac
    25381 gttcaattgc ttttctttat cagagaggaa gttttccatt tccgtcagaa tgtctatatc
    25441 caaacgttga gaaagttcta atagccacca gatattttct gaaagttttt gttccagtgt
    25501 gtagggtgtt tcatcatagt agcgtccttg ctttgtcatc accagtcatt ggaaatttcc
    25561 aatatcatta gataaagcca agaggtcttc ttctaccgtc cacttgaaat catgatgctt
    25621 aacttccagt tcgtgataag cttgtcggat tgcccaactg cgctccacta attcttgcaa
    25681 ctccataatt agtatcctaa taaaaaaatg cgacatcctc gaaaggacgt cgcaacgtgg
    25741 ttccaccttc atttatgtac ctcaaaagag agggacacct ctgatcggct ctaacgtggc
    25801 caccgtttta tgttttcata aaaaactcaa gagtagtatc agtttagact tcctatgcgt
    25861 ttccagcaac cacgcactct ctagtagaaa gggactaagt gacttgtctc tatggattat
    25921 tatagcatga ttgtgagatt tttcaaggat tttgtgaaag ttttttgttt ttcatttttt
    25981 gtagaatatg cttgatgcta ataccagaat ccatgctcac cagagcaact gtttcataga
    26041 ttagcaagta aattagtata aactcaccaa aggttatgat agtaaagtaa aagagcagtc
    26101 cgttaccaac taaccaccaa agtgagaaac ggaaacggta gctatagagt aacgatataa
    26161 tcaagattac cagaggtgta aagaagagaa gattgtttat atagagtccc ttgagtgtaa
    26221 gggggtcaga aacaactagc aagaacaact cataaagtgg ccaataaaag aataatatga
    26281 ccagatagta ggggagatgg gaatagaatc tacgcatgat aatcacctcg ttttaaaaaa
    26341 acagacaact tagatctctt gctatgatta ttatagcatg tttaaaacaa gaaagtaaat
    26401 ttgttgacaa agaagatttt tcttttccct agaatcatag ttagttttct tggtagaaat
    26461 attttgataa taattaagca agactattga cattgattat taagagtgtc acaattgttg
    26521 taactaaaat aattacaaca agagaggtat aaaaaatgaa actagcagtt attgcagcaa
    26581 atggacaagc ggggaaggca attgttgaag aagcagtcaa acgaggacat gaagtaacgg
    26641 ctattgttcg ttctgaaaac aaaagtcaat ctgagtctat tattaaaaaa gatttatttg
    26701 agttgacaaa agatgatctt actggatttg atgctgttat ttcagcgttt ggtgcttata
    26761 caccagatac gctaccgctc cacagcaaat caatcgaact atttaatcag cttcttgctg
    26821 gaacacagac acgttttcta gttgtagggg gatcaggaag cttttatata gatgaaacaa
    26881 aaacgacacg acttttagat acgtctgatt ttcctgaaga atttaagcca ctagcaaaag
    26941 ctcaagcgga tgaattggat ctttttcgta caaaaaataa tctcaactgg acttttgtca
    27001 gtcctgctgt agattttatt cccgatggtg aaaaaacagg aaactacatt ctagcaggag
    27061 aaatttttac tactaatgaa aaaggaataa gccagattag ttatgcagat tatgctattg
    27121 gattggtaga tgaacttgaa aaaggtcatc atataaaaga acgtatctct ttacttgaaa
    27181 aataataact atgagagtat taatgtttga cagaaaattt aaatcttggt agaataggga
    27241 ttgtcgtaaa gacaaataac ttcttcttgg ttacaggcat gccaacctgt cactcggatg
    27301 aagccaaata aaaaggagaa acatcatggc aatctcaaaa gagaaaaaaa atgaaatcat
    27361 cgcacaatat gcacgtcacg aaggtgatac aggttcagta gaggttcaag ttgctgtcct
    27421 tacttgggaa atcaaccacc ttaatgaaca catcaaacaa cacaaaaaag accacgctac
    27481 ttaccgtgga ttgatgaaaa aaatcggtcg ccgtcgtaac ttgcttgcat acttgcgtaa
    27541 aaacgacgtt aaccgttacc gtgagttgat caactctcta ggacttcgtc gctaattcaa
    27601 gatacaaagg ctgtcaaaag cacaaagtaa aaataggaaa attgacgaag aaacttcagt
    27661 ttctaggaga ttttatcttt tttgccaagt gcttaggccg tgttcaattg agcatatctt
    27721 gataatgaag ctactctaaa ttgggtagct tttttgtgtt gtcaccttac ctcgatatac
    27781 tcaagtataa tctttggtta cggttcctag cactgtaagg taaaataaac cagcttttct
    27841 cccttcgggg agattttttt gtttcactga aagtttcgta cgatcttcgc ctcgtcgcct
    27901 agtctataaa cgatttatct agcaagaatc atgatgctaa gggcgtcaaa aatccgtatg
    27961 aaaataggga aatgacacag tgttcgatga gcacaaggag tttcatcttt ttcactagga
    28021 ttttagcccg gactcaaatc agctctctga cttcagaggg cttttttatt gaggttttat
    28081 cggtaacaat tttggagact acaaaaacct caaacggtat cagctaatta caccataaag
    28141 gtgcgcagtt actcggcttt tcaagccgag tagttgtatg caagccccct agaagagccc
    28201 actctttaca aagtaaagta tagtatgtta tactttacat ggaagtagtc actgaattcc
    28261 agttagaaat tactttgtaa ctacgttttg aggaggagta aaatgctttc ctacgttcga
    28321 tattacccac tagcgatagc taaattaatg tgtctgtgct ctcctaaaat ctgctgattt
    28381 attactgact aatacaggag ttttttttat gggacagaca atcatatctg ctattggtgt
    28441 ttatatttcc accagtatcg attatttaat tattttaatt attttatttg cacagctatc
    28501 acagaataaa cagaaatggc atatttatgc ggggcaatat ctaggcacag gcttacttgt
    28561 aggggcgagt ttagttgctg cttatgtcgt taatttcgtg cctgaagaat ggatggttgg
    28621 attgcttggt ttaatcccta tctatttagg gattcgcttt gcaattcttg gagaagatgc
    28681 ggaagaagaa gaggaagaaa ttattgaaag attagaacaa agcaaggcaa atcaactgtt
    28741 ttggacagtt acattgctga caattgcgtc tggcggagat aatttaggta tctatatacc
    28801 ttattttgct tcgttagatt ggtcacagac cctcgtggcc ttgcttgtgt ttgtaatcgg
    28861 cataattatc ttttgcgaga ttagtcgggt gttatcctct attccgttaa tattcgagac
    28921 aattgaaaaa tacgagcgaa tcattgtgcc cttagtattc attctacttg gactatacat
    28981 catgtatgaa aatggcacga tagagacttt tctgatcgtg tagatttttt tgtttcacta
    29041 ggattttagc ccgagctcaa atcagctctc tgattttcag agggcttttt cattgagtat
    29101 aaatggacaa tcttaaagtt actctattgt agagtggctt ttgatttgat taggagattc
    29161 ttataaatat agtaaaatga aacaaaaaca ggacaaatcg atcaggacag tcaaatcgat
    29221 ttctaaaaat gttttaagaa gtagaggtgt actattctag tttcaatttg atatataaat
    29281 gaaaacctta gctgtttggc caaggttcat ttcttctatg caagttcttc tcttttctta
    29341 tctgggttcc agatgaagct tgcgataaag ctaaagatga tggttaggat agcgaggata
    29401 atagcaagga tgagggcagg gatgcggata aaccaccaga gtggatttgg ttttttatca
    29461 ttgtgccatt gtttcgtttc ttcgtccaga cgttggaatt ctgtttgaat acgattggcg
    29521 actgtttcaa tgccttcatc attcattttc ttgatatctg agatatcgat tggatttcca
    29581 aagttcatat cgacacgttc acggctaatc aagcccttca aagtcatggg accggtgtag
    29641 gtaaccggca tgatacggac tttggccatt ttggcaatca gtgctgcgcc ccccttgaca
    29701 tcgtttgagt ggcggctacc acttggaaac atgatgagag agcggtcact ttttttgaga
    29761 acgttgatag gatatttgat ggctgaggcg ctgggatttt cacggtcgat gggaaaggcg
    29821 ccacacatac gaatccacca accaaagata cggttggtaa agagttcttt ttttgccata
    29881 aagatgaact gttttggctt ggtcgcaaag gccatataaa caggatccca ccaggtacgg
    29941 tgaggcgcaa ctaaaatata attttcatct tgattaggaa ttttatcagt attatgatag
    30001 tgagcattgc cattgatgga ccataagagc aatacaacta atccacgcaa ataagtataa
    30061 aacatgcgat ctccttcgat tgttttcttg ttattattat accttatcaa aggagggctg
    30121 gcaaact
//
LOCUS       DAVDZK010000029        30036 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVDZK010000029 DAVDZK010000000
VERSION     DAVDZK010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30036
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.030"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            249..770
                     /gene="pyrR"
                     /locus_tag="VUX16_001475"
     CDS             249..770
                     /gene="pyrR"
                     /locus_tag="VUX16_001475"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET8124420.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVADREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            789..1712
                     /locus_tag="VUX16_001476"
     CDS             789..1712
                     /locus_tag="VUX16_001476"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET8124421.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPCEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIVNGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            1762..2841
                     /gene="carA"
                     /locus_tag="VUX16_001477"
     CDS             1762..2841
                     /gene="carA"
                     /locus_tag="VUX16_001477"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET8124422.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            3153..6329
                     /gene="carB"
                     /locus_tag="VUX16_001478"
     CDS             3153..6329
                     /gene="carB"
                     /locus_tag="VUX16_001478"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET8124423.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAIEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGGRRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLETGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGLENESIKSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(6604..7413)
                     /locus_tag="VUX16_001479"
     CDS             complement(6604..7413)
                     /locus_tag="VUX16_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET8124424.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(7415..8218)
                     /locus_tag="VUX16_001480"
     CDS             complement(7415..8218)
                     /locus_tag="VUX16_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET8124425.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSHENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(8228..9715)
                     /gene="tacF"
                     /locus_tag="VUX16_001481"
     CDS             complement(8228..9715)
                     /gene="tacF"
                     /locus_tag="VUX16_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET8124426.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRAFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVLPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            10051..10758
                     /locus_tag="VUX16_001482"
     CDS             10051..10758
                     /locus_tag="VUX16_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET8124427.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            10763..11785
                     /locus_tag="VUX16_001483"
     CDS             10763..11785
                     /locus_tag="VUX16_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET8124428.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            11802..12671
                     /gene="licA"
                     /locus_tag="VUX16_001484"
     CDS             11802..12671
                     /gene="licA"
                     /locus_tag="VUX16_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET8124429.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAIRLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            12661..13539
                     /locus_tag="VUX16_001485"
     CDS             12661..13539
                     /locus_tag="VUX16_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET8124430.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKIRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIVINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            13551..14240
                     /locus_tag="VUX16_001486"
     CDS             13551..14240
                     /locus_tag="VUX16_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP--phosphocholine cytidylyltransferase"
                     /protein_id="HET8124431.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DASTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            14337..15185
                     /gene="dprA"
                     /locus_tag="VUX16_001487"
     CDS             14337..15185
                     /gene="dprA"
                     /locus_tag="VUX16_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET8124432.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIANIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            16069..17112
                     /locus_tag="VUX16_001488"
     CDS             16069..17112
                     /locus_tag="VUX16_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET8124433.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            17279..19366
                     /gene="topA"
                     /locus_tag="VUX16_001489"
     CDS             17279..19366
                     /gene="topA"
                     /locus_tag="VUX16_001489"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET8124434.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFDS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            19587..19946
                     /locus_tag="VUX16_001490"
     CDS             19587..19946
                     /locus_tag="VUX16_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET8124435.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            20039..20671
                     /locus_tag="VUX16_001491"
     CDS             20039..20671
                     /locus_tag="VUX16_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET8124436.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            20715..21371
                     /locus_tag="VUX16_001492"
     CDS             20715..21371
                     /locus_tag="VUX16_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET8124437.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMRISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTYKK
                     "
     gene            21390..22484
                     /locus_tag="VUX16_001493"
     CDS             21390..22484
                     /locus_tag="VUX16_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET8124438.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            22496..23533
                     /gene="leuB"
                     /locus_tag="VUX16_001494"
     CDS             22496..23533
                     /gene="leuB"
                     /locus_tag="VUX16_001494"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HET8124439.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNCRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSILSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVVMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMMEAIIARL"
     gene            23530..23799
                     /locus_tag="VUX16_001495"
     CDS             23530..23799
                     /locus_tag="VUX16_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET8124440.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            23803..24162
                     /gene="leuD"
                     /locus_tag="VUX16_001496"
     CDS             23803..24162
                     /gene="leuD"
                     /locus_tag="VUX16_001496"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET8124441.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNDLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            24324..24894
                     /locus_tag="VUX16_001497"
                     /pseudo
     CDS             24324..24894
                     /locus_tag="VUX16_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            24988..25053
                     /locus_tag="VUX16_001498"
                     /pseudo
     CDS             24988..25053
                     /locus_tag="VUX16_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            25216..27147
                     /locus_tag="VUX16_001499"
     CDS             25216..27147
                     /locus_tag="VUX16_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET8124442.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNESDENDDADY"
     gene            27134..28450
                     /locus_tag="VUX16_001500"
     CDS             27134..28450
                     /locus_tag="VUX16_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET8124443.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKKQKILETINQEIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPLTGNIAYTTREFTYDNPLMQLICHTIEYIKNQKSIGQGVLDSLLTS
                     RENVSEIMRVTPSYKLADRAKIIRGNKSKPIRHAYFHEYRKLQELCLMILNQEKHGLG
                     YQDQKIHGILFDVAWLWEEYVHTLLPKDFIHPRNKDKTDGISVFSSRERKVYPDFYNR
                     DLKIVLDAKYKKLEDTEKGINREDLFQLISYSYILKAEKAGLIFPSEKKAVDNEIGKL
                     AGYGALLKKWSIQIPQNSSSYREFCEMMERSEESFKRNITKELGRK"
     gene            28624..29610
                     /locus_tag="VUX16_001501"
     CDS             28624..29610
                     /locus_tag="VUX16_001501"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET8124444.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGSYFYIMHRFDEAGRIPFIKRMHEQGLIASISVGVKDYEY
                     DFVSQLKDDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            29674..29745
                     /locus_tag="VUX16_001502"
     tRNA            29674..29745
                     /locus_tag="VUX16_001502"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29707..29709,aa:Arg,seq:ccg)
BASE COUNT         9378 a         5290 c         6395 g         8973 t
ORIGIN      
        1 accagtaccc acaattatat gattttagca atttgtaaga tgctacattg aaactttttg
       61 cttgatttta agcatgcttt gtgctatagt aaatgataac taaatattcc tttaaacctg
      121 tcccgtgagg caggcaagga gcgcgataaa gtagaagggt gaagtctata ctgtgtgcag
      181 tagggctcgc ttggctataa atttcaagtc tccttgttta aggagacttt tctttttgga
      241 ggtttgtcat gaaaacaaaa gaagttgtag acgaattgac cgtcaaacga gcgattacgc
      301 gtattactta tgagattatc gaacgcaaca aagatttgaa taagatcgtc ttggctggta
      361 ttaaaactcg tggtgtcttt attgcccacc gaatccaaga acgtttgaag cagttagaaa
      421 atctttcagt tcctgttgtg gaattggata ctaaaccttt ccgtgatgat gttaaaagtg
      481 gagaagatac ttctttggtt tctgtcgatg tggcagaccg cgaagttatc ttggtggatg
      541 atgtgctcta tacaggtcgt accatccgtg ctgctattga taatattgtc ggtcatggtc
      601 gtcctgcgcg tgtgagttta gcagttctag tcgatcgtgg acatagagaa ttgccaatcc
      661 gtccagatta cgttggaaaa aatatcccaa ccagtcgttc tgaagaaatc atcgtagaga
      721 tgacagaact tgatgaccaa gacagagttc tgattactga agaagcttag aaagttaaag
      781 gagtagccat gtcagaaaat caacaagcat tgaaccatgt ggtgtccatg gaagacctca
      841 ctgtcgatca agtgatgaaa ttgatcaagc gaggaattga gtttaaaaat ggagcccagc
      901 ttccctgtga agaccatccg attgtttcca atctcttctt tgaggattct acacggacac
      961 ataagtcctt tgaagtcgca gagattaaac ttggattgga acgacttgac tttgatgtga
     1021 agactagttc ggttaataag ggtgagacac tttatgacac cattttgact ctgtctgctt
     1081 taggagtgga tgtctgtgtg attcgccatc cagaggtcga ctactataga gaattgattg
     1141 ctagtccaac gattacgact tccatcgtca atggtggaga tggttcgggc caacacccta
     1201 gccagagctt gcttgatttg atgaccattt atgaggaatt tggccacttt gagggtctta
     1261 aagttgctat tgcaggtgac ttggatcact cacgcgttgc caaatccaat atgcagattt
     1321 tgaaacgctt gggagctgaa ctctttttcg ctggacctga ggaatggaga agtcaagagt
     1381 ttgcagacta tggacagttt gtaaccattg atgaaatcat tgatcaggtt gatgtcatga
     1441 tgtttctccg tgtgcaacac gaacgccatg atagtggagc tgtattttca aaagaagact
     1501 accatgccca acatggcttg actcaagaac gttacgatcg tttgaaagaa acagcaatcc
     1561 tcatgcaccc agctccaatc aatcgtgatg tagaaatagc agaccacttg gttgaagcac
     1621 caaaatcacg gattgtccaa caaatgacca atggtgtctt tgttcgaatg gcaatcttag
     1681 aatccgtact agcgagtaga aacgccaact aaaacacaag acgttaaaag acgccagtga
     1741 gcgtccacga gaggtgaaaa tatgacaaaa agaattctag tattagaaga tggcacagtt
     1801 tttgaaggca aggccttcgg agcagatatt gatgtaacag gcgaaatcgt ctttaataca
     1861 ggaatgaccg gctaccaaga atccattaca gaccagtctt ataatggaca aatcttgacc
     1921 tttacttatc ctttggtagg aaattatggt attaatcgtg atgattatga atccattatt
     1981 ccaacttgta agggagtcgt tgtttttgaa gaagcgcgta gagctagcaa ctggcgcaac
     2041 caaatgacct tggatgaatt tttgaaagcc aagaaaattc cagggatttc aggaattgat
     2101 acgcgtgctc ttaccaagat tatccgtaag catggtacta tgcgtgcaac cttgacccat
     2161 gttggggaca gtatggacca tgtgacggac cagctccaag caacagtttt accgacagac
     2221 aatatcaaac aggtttctac taaaacgtct tatccagctc caggagttgg tttgagcgtg
     2281 gtgctagtgg actttggtct caagcactca atcctacgtg aactttctaa acgcaactgt
     2341 aacgtgacag ttgttcctta ttcgacaacg gctgaagaaa ttctccatct caatcctgac
     2401 ggagttatgt tgtcaaatgg tccaggtaac ccagaagacg ttccacaagc actcgacatg
     2461 attcgcggtg tacaaggaaa aataccaatc tttggtattt gtatgggaca ccaactcttt
     2521 gcaatggcaa acggggctaa gacctataag atgaagtttg gccaccgtgg attcaaccat
     2581 gcggtacgtg aaatcgcaac aggacgagta gacttcacca gccagaacca tggttatgca
     2641 gtcagccgcg aggatttgcc agagcacttg attattacac acgaagaaat caatgacaag
     2701 tcagtggaag gtgtgcgcca cagataccaa cctgctttct ctgttcaata ccacccagat
     2761 gcagctcctg ggccacacga cgctagctac ctatttgacg agtttatcga gatgatggaa
     2821 gtttttaaac aatcaaacta agaacgagta aaagctcgtc ggagaattta tgtaactgaa
     2881 cacggacgga aagctcagaa tttagagaaa ccaacttgga ttgtcaatcc ttccttgatt
     2941 ttctaaaatt caatcgcttt ctattcgtcc tttgtatctt atttaatgtc gccctgagag
     3001 gcgacgaata gaaaggagaa gggtgctccg tatttgctga actgaatacg ggctacggac
     3061 ggtgctaaaa agatagttat tcctagaact gacagttcta ggaataactc ctattttagc
     3121 tttgtccgct tgacgccctt aatatcttat atatgcctaa acgtactgat attcaaaaaa
     3181 ttatggtgat tggttctggt ccgattatta ttggtcaggc tgctgagttt gactacgctg
     3241 ggactcaggc ttgcttgtcg ttgaaagagg aaggttatga ggttgttttg gttaactcaa
     3301 atcctgcaac catcatgacg gacaaggaaa ttgctgacaa ggtttacatt gaaccgatta
     3361 cacttgagtt tgtgacacgt attcttcgta aggaacgtcc agatgccttg ctaccaacac
     3421 tcggtggtca gacaggtctc aacatggcca tagaattgtc taaaaatggt atcttagatg
     3481 agcttggcgt tgaacttctg ggtaccaaat tatctgccat tgaccaagcg gaggaccgtg
     3541 acctctttaa acaattgatg gaagagcttg aacaacccat tccagaatct gaaattgtta
     3601 acacagtaga agaagcagtt gcctttgcag cgacaattgg ctacccagtc atcgttcgtc
     3661 cagcctttac cctcggtggt actggtggtg gtatgtgtgc caatgagaaa gaattgcgtg
     3721 aaatcactga aaatggtttg aaattgtcac ctgttaccca atgtttgatt gagcgttcga
     3781 ttgccggttt caaggaaatt gaatacgaag tgatgcgtga ctcagctgac aatgccttgg
     3841 ttgtttgtaa catggaaaac tttgacccag ttgggattca cacaggggat tccattgtat
     3901 ttgcccctgc gcaaaccatg tcagactatg aaaaccaaat gcttcgtgat gcgagcttga
     3961 gcattattcg tgccctcaag attgaaggtg gatgtaatgt tcagctagct cttgatccta
     4021 acagcttcaa gtattatgtt atcgaagtaa accctcgtgt atcacgttcg tcagcccttg
     4081 cttctaaagc gactggatat ccgattgcta agttggctgc caagattgca gtaggtttga
     4141 ccttggatga ggttataaac ccagttacag gttcaaccta tgccatgttt gaaccagccc
     4201 ttgactacgt agttgctaag attccacgtt tcccatttga caagtttgaa aagggtggac
     4261 gccgtctcgg tacacaaatg aaggcgactg gagaagtcat ggcaatcggt cgtaatatcg
     4321 aggaatctct tctcaaggcc tgccgctccc ttgaaactgg ggtgcaccac aatgaaatac
     4381 ctgaacttgc agcagtttct gatgatgcct tgattgaaaa ggttgtcaaa gcccaagatg
     4441 accgtctctt ctacgtatca gaagcaattc gtcgtggcta cacacctgaa gaaattgcag
     4501 agctaacaaa aattgatatc ttctatcttg ataaactctt gcatatcttt gaaattgagc
     4561 aagaattggg tgctcatcca caagatctag aagttttgaa aacagccaaa cttaatggtt
     4621 tctcagaccg taagattgct gaactctggg gaacgactga tgatcaagtt cgccaacttc
     4681 gcttggaaaa caagattgtt ccagtttata agatggtaga tacttgtgcg gcagagttcg
     4741 actctgaaac gccatatttc tattcaacct atggtttgga aaatgaatct atcaaatctg
     4801 ataaagaatc tgtacttgtc ctaggttcag gtccaatccg tatcggtcaa ggggttgagt
     4861 ttgactacgc aaccgttcac tctgttaagg ctatccaggc agctggttat gaagctatca
     4921 tcatgaactc aaacccagag accgtttcaa cagacttctc tgtatcagat aagctttact
     4981 ttgagccatt gacattcgaa gatgttatga acgtcattga cttggaacaa ccaaagggag
     5041 ttatcgttca gtttggtggt caaacagcca tcaaccttgc ggagccattg gcaaaagcag
     5101 gtgtgaccat ccttggtaca caggttgctg acctagaccg tgccgaagac cgtgacctct
     5161 tcgagcaagc tctcaaagaa ttggatattc cacagccacc aggacaaacg gctaccaatg
     5221 aagaagaagc agctcttgca gctcgtaaga ttggcttccc agttcttgtc cgcccatctt
     5281 atgtacttgg tggacgtgcc atggaaatcg ttgaaaacga agaagacctt cgttcttaca
     5341 tgcgaactgc tgttaaggct agtccagatc atccagttct tgtcgactct tatatcgttg
     5401 ggcaagagtg cgaagttgat gccatttcag atggtaaaga tgtactcatt cctggtatca
     5461 tggagcatat cgaacgtgct ggtgtccact caggtgactc aatggctgtt tacccaccac
     5521 aaaccttgtc gcaaaaagtt caggagacca tcgcagacta caccaaacgc ttagcaatcg
     5581 gtcttcactg ccttggaatg atgaacatcc agtttgttat caaggatgaa aaagtctacg
     5641 ttattgaggt caatccacgt gccagccgta ccgttccatt tctatctaag gtaaccaata
     5701 ttcctatggc tcaagtagcg accaagctca ttcttggtca aagtttatca gaacttggct
     5761 accaaaatgg actttaccct gaaagcaccc gtgttcatat caaggcacct gtcttctcct
     5821 ttactaaact agctaaggta gacagcttgc tcggtcctga aatgaagtca acaggtgaag
     5881 ttatgggttc tgatgctact ttggaaaaag ctctctataa agcctttgaa gcttcttatc
     5941 tacacttgcc aacttttggt aatgtcgtct ttaccatcgc tgatgatgcc aaagaagaag
     6001 ccttgaactt ggctcgtcgt ttccaaaaca ttggttatgg aatccttgcg acagaaggga
     6061 cagcagcctt ctttgctagt catggcttgc aagcccaacc tgttggtaag attggtgatg
     6121 acgataagga tatcccaagt tttgtacgca aaggaagaat tcaagctatc attaacacag
     6181 taggaacaaa acgaactgct gacgaagatg gtgagcaaat tcgtcgttca gccattgaac
     6241 acggggtgcc cctcttcaca gcgctagata cagctaatgc catgcttaag gtacttgaaa
     6301 gtcgtagctt tgttacagaa gcgatttaaa tagaaaaata agatatagca gactgaattt
     6361 agaacagtac acagggatac taaaatattt ctagaaatta atttgaattt tctaattgat
     6421 tcgttcgcat cttatttcaa tctactatag aaaaaagtct ttaaaattat aaaacgcatc
     6481 atatcaaggt ttttcaaaaa ccctgatatg atgcgtttta ttgtgggaat atgtatttca
     6541 ttttctacta aaattatgtt tttgaataac ctctatctta gtagtttgta taatccccct
     6601 caatcagttt ttgcgataag ctttaatgct atgactatac cactcttgca tttcttttga
     6661 tggtggtgtc atataatcgc catacatctg ggttaaaaat tggtcatatt ttttgggaac
     6721 aggcaacata cggccctcaa actcagttaa aatcagttct ttaaaggtat caactgggaa
     6781 gatttctttc atcccttcct taccgatccc aactcctcct tcatattgag gagtgttggt
     6841 tacagcattt ttgactagtt gatcaatttt cttgtaaaag tagcgaggat tgacaaatcg
     6901 gagagcgtac caactacata atctaagaaa atcttttagt ttgctatcac cgtgaactgc
     6961 tcgtgatttt ttgatataag ctagttgacg aagggccaca tacttatagc tcttgtcgac
     7021 aatgctcaag tctgtaaatc gatcaattgg gaagacatcg atgaaaaggc tggtatcatg
     7081 acgcttgtac ttaacatggt cttctataac agtagaagtg tccaaaatcg atgcgaaatt
     7141 atggaagtac caagaagatg tatcgtagga aagaaccttg tagcgagggt gattttcttc
     7201 ttcaataatc ttcagtaaac gctcataatc ctcacgataa agggaaatat caatatcatc
     7261 atcccaagga atcatacctt tgtggcggat ggctccaagc atggttccat aactgagaaa
     7321 ataaggaata tcatgtttct tacaagtctc atcaatatag tccagcaggg ctagttgaat
     7381 ttctttaatt tctttttttt ctaaatattg catcctaatc ctccaattta taagcgtgaa
     7441 attcatgact gtagaagcgt ttttcttctg gtggtagggt catataatct ccataaaatt
     7501 gtgtcaaaat agtatcaaat ttttcaggtg caggaaggct taaattctca aagggtaaat
     7561 cgattgtttt atcaaaggta ccacttggga agacttcctt ttccttaaat tttgaaggga
     7621 taaaagccat atactgccca ttttcatgac tatatttttg aatttctttc tcgattttat
     7681 ttgcaaaata acgaggagaa accggtcgaa ggagcaacca aaaggctgtt cgtatccaat
     7741 cttttaaaag gctatcctta tagacaatat ttttatgttt actgaaagac agcagtttga
     7801 agctttccag tttataacaa gtatcaatga ccttaggatc atcaaagcga tctataggga
     7861 aaatatcgat aaagatacca gactcatagg tttttgtatt tcgagtatca ataattttag
     7921 tcgtactgtc ggttatcttg ataaagttgt taaagtagtt cttatcagtt tctaaggata
     7981 ggagcttata cttgcttttt tccttttgaa aaatgttaat aaatcgttgg tagtcttctc
     8041 taggcatgga taaatcaata tcgtcgtccc aagggataaa gccctcatgt cgaaccgccc
     8101 caatcagagt accgtagtta ataatatagt tgatattgtg ctttttacag agagtatcaa
     8161 tataatccaa aatttctaat tcaatttgtt tggcatcttc aacggttagt tgtttcattt
     8221 taaactccta tgatttttta aatttatttt ttaaggctag gacatggttt aaaaattcat
     8281 agaaaatgct atcttttgtg aagacaagta gactaatata agagatagct gatagcaaga
     8341 caatcaaacc agtattaatt aaaaatggca aattaatgac catatccaca ggatacacga
     8401 aattaatcag gaaataaatt gctacaaagg aaagtgaaaa gagagagtat cgaacagtat
     8461 agctaaagat atgtcccaag tggatgagtt gttttctatg gatgaaaata atatagaaaa
     8521 caagtagaga agtctctgat aacatagttg tcagtaagta gtattcagga agcacgatat
     8581 ggttgaaaaa gaggagacta ttcaagccca aattgagtag cccagcaaag actgtataga
     8641 ctgtgatacg tttttcatag ccattggtaa agagaatttg ggaaccaaga atggtatcta
     8701 aggccaggat aatcgtacga aaagcgaaga gagaggtcaa gatgccgcct ccgatatatt
     8761 tttcactacc gtaaagtagg atggcatttg gtcctaaaac catgagtcca aaactcagtg
     8821 gaatgataaa gaagttaaag attcgactac ctctattaac cagagaaaca taggcttctt
     8881 tgtctccttt ccccagatag taactgagac gaggcacact cactccaatt gcacctgtta
     8941 caaccccagc tataacggtc acaattcgct gagctatggt atagtaacta acgttgacat
     9001 caatccctgt tttaacgagg aagaggcgat ctaaaaaagt gaagagcata ttggcattgg
     9061 caaagactaa catggctgtc agagggagaa agagtggttt aaaatcactt aggtgaatct
     9121 taacaagttt gatgtctctt ttaatccaaa aataactaat caggtagtta atcagcgtcg
     9181 ataaactcat cacaagtgta tagacaacaa tatcgtgttc atttttaaca aataagaaaa
     9241 tagagaccag catcaggata cggatgaagg cagttttgta aaagagaaaa ctgtaatttt
     9301 ccagagcttc attgacccat tcgattgaaa aaatctgggc aatgagttga atccccataa
     9361 caaggtagac ctttttgacg attggattat cagtaaagaa gagaggatag gctaggatat
     9421 agacagcagt ggtcaaaatc gtacaagcga tgcacaaata aaaaagacta gaaaaggctc
     9481 tgttaagatc ttttttgtta tccttgacat tactgatagc ccttaaaccg tagttataga
     9541 caccataagt tgcaaagggc aagaaaaatg acaaaatagt gtcgactgag ttgaagtaac
     9601 catagtcagt tcggtccaag acacgcgcga cataggttcc agttaggatg ggaaaaataa
     9661 tattcaagac acgaattccc atgtaagata gagcatttaa ttttatactt ttcattcaat
     9721 ttacctcgtt tttcattata tcataaagtt agctaataag aaatgaaggg cagtaagtca
     9781 agtaatcact ttgaagtttc aaatcttaaa ttttaagttt tctttaagga aagtatatta
     9841 ttctgaagga ctctaaaatt tcgcaaccat ttattagtaa ttgctacaga attcctagtc
     9901 attactagaa atggactagt ttctttgaat aatagaactg cataattctc ctattctaga
     9961 aggggaggac cagtatttct tttatgatag gactagattg tggtataata gagagaataa
    10021 gtttttttag taagacaaag gagaaaatag atgatttatg caggaattct tgctggtgga
    10081 actggcacac gcatgggaat cagtaacttg ccaaaacaat ttttagagct aggtgatcga
    10141 cctattttga ttcatacaat tgaaaaattt gtcttggagc caagtattga aaaaattgta
    10201 gttggtgttc atggagactg ggtttctcat gcagaagatc ttgtagataa atatcttcct
    10261 ctttataagg aacgtatcat cattacaaag ggtggtgctg accgcaatac aagtattaag
    10321 aaaattattg aagcgattga tgcttatcgt ccgcttactc cagaggatat cgttgttacc
    10381 cacgattctg ttcgtccatt tattacactt cgcatgattc aggacaatat ccaacttgcc
    10441 caaaatcatg acgcagtgga cacagtggta gaagcggttg atactatcgt tgaaagtacc
    10501 aatggtcaat ttattacaga tattccaaat cgtgctcacc tttatcaagg acaaacacct
    10561 caaacattcc gttgcaagga cttcatggac ctttatggat ctctttctga tgaagagaag
    10621 gaaatcttga cagatgcatg taaaatcttt gtgatcaaag gaaaagatgt ggccttggcc
    10681 aaaggcgaat actcaaatct gaagattaca accgtaacag atttgaagat tgcaaaaagt
    10741 atgattgaga aagactagta aaatgattaa tcaaatttat caactaacta agcctaagtt
    10801 tatcaatgtc aaatatcagg aagaggctat tgaccaagag aatcatatcc ttatccgtcc
    10861 caactacatg gctgtctgtc atgcggatca gcgttactat cagggaaaac gtgatcccaa
    10921 gattttgaat aaaaagcttc caatggcgat gattcacgag tcatgtggaa ccgtcatttc
    10981 tgacccgacc ggaacctacg aggttggtca aaaagttgtc atgattccca atcagtctcc
    11041 tatgcagagt gatgaagaat tctatgaaaa ctacatgaca gggacccatt tcttgtctag
    11101 tggatttgat ggctttatga gagagtttgt ttctctccct aaagatcgtg tggtggctta
    11161 tgatgctatt gaagatacgg ttgcagccat tacagagttt gtcagtgtgg gcatgcacgc
    11221 tatgaatcgt ctattgactc ttgctcatag caagcgggag cggatcgccg ttattggaga
    11281 tggaagttta gcttttgtgg ttgccaatat tatcaactat actttgccag aatcagagat
    11341 tgtggttatt ggtcgtcatt gggaaaagtt ggaactcttc tcatttgcca aagaatgcta
    11401 tattacggat aatattcctg aagatttggc ctttgaccat gcttttgaat gttgtggtgg
    11461 tgatggtact ggaccagcta ttaatgactt gattcgctac attcgtcctc agggaacgat
    11521 tctcatgatg ggagttagcg aatataaagt caatctcaat actcgcgatg ccttagaaaa
    11581 gggcttgatt ttggttgggt catctcgttc tggtcgcatt gattttgaaa atgctatcca
    11641 aatgatggaa gtcaagaaat ttgccaatcg tcttaaaaat atcctttatc tagaagaacc
    11701 tgtaagagaa attaaagata ttcatcgtgt ctttgcaacc gatttaaaca cagcctttaa
    11761 aacagtgttt aagtgggaag tataagtact ggaggttaat tgtggagaaa atcattaaag
    11821 aaaaaatttc ttccttactt agtcaagaag aggaagtcct cagtgttgaa caactgggtg
    11881 gaatgaccaa tcaaaactat ttggccaaaa caacaaataa gcaatacatt gttaaattct
    11941 ttggtaaagg gacagaaaag cttatcaatc gacaagatga aaagtacaat cttgaactac
    12001 taaaggattt aggcttagat gtaaaaaatt atctttttga tattgaagct ggtatcaaag
    12061 taaatgagta tatcgaatct gcgattaggc ttgattcaac gtcaatcaag accaagttcg
    12121 acaaaattgc tccaatatta caaactattc atacgtctgc taaggaatta agaggagaat
    12181 ttgctccttt tgaagaaatc aaaaaatacg aatccttgat tgaagaacaa attccttatg
    12241 ccaactatga atctgttaga aatgcagtct tctccttaga gaaaagactg gctgacttag
    12301 gtgttgacag aaaatcttgt catatcgatt tggtgcctga aaactttatc gaatcacctc
    12361 aaggacgact ttatttgatt gactgggaat attcatcaat gaatgatcca atgtgggatt
    12421 tggctgccct ctttttagag tctgaattca cttcccaaga ggaagaaact ttcttatctc
    12481 actatgagag tgaccaaaca ccggtttctc atgaaaagat tgctatttat aaaattttac
    12541 aagatactat ttggagtcta tggactgtat ataaggaaga gcaaggtgca gattttggtg
    12601 actatggtgt gaatcgttac caaagagctg ttaaaggttt ggcttcttat ggaggttcag
    12661 atgaaaagta aaaacggagt tccttttggc cttctctcag gtattttctg gggcttgggt
    12721 ctaacagtta gtgcttatat cttttcgatt tttacagatt tgtcaccctt tgtggtggcc
    12781 gctgctcacg atttcttgag tatctttatc ttactggctt ttcttttagt aaaagaaggg
    12841 aaaattcgtc tctcaatttt cttaaatatt cgcaatgtca gtgttatcat cggagccttg
    12901 ctagcaggtc ctattggtat gcaggccaat ctttatgcag ttaagtatat cggaagttct
    12961 ttagcttcat ctgtatcggc tatttaccct gcgatttcag ttctattggc tttcttcttt
    13021 ttgaagcaca agatttcgaa aaatactgta tttgggattg tcttgattat tggagggatt
    13081 attgcccaga cctataaggt tgaacaggtt aattccttct acattgggat tctctgtgct
    13141 ttggtttgtg ctattgcatg gggaagtgag agtgttctta gctcctttgc tatggaaagt
    13201 gaactgagtg aaattgaagc cctcttaatc cgtcaagtga cttcgttctt gtcctatctt
    13261 gtgattgtgc tcttctctca tcagtcattt gttgcagtag ccaatggaca attgctaggt
    13321 ctcatgattg tctttgtagc ctttgatatg atttcctact tggcttatta tatcgttatc
    13381 aatcgcttgc aaccagccaa ggctacaggc ttgaacgtga gctatgtagt atggacggtc
    13441 ttgtttgcag ttgttttttt gggtgcaccg ctagatatgc tgaccattat gacgtcactt
    13501 gtcgtcattg ctggagttta tattattatt aaagaataaa ggagattcgt gtgaaagcca
    13561 ttatcttagc agcgggattg ggaactcgct tgcgtcctat gactgaaaat acccctaaag
    13621 ccttggttca ggttaatcaa aaacctttga ttgaatacca aattgagttt ctcaaagaaa
    13681 aaggaatcaa tgacatcatc atcatcgttg gttatcttaa agaacaattc gattatttaa
    13741 aagaaaaata cggtgttcgc ctcgttttca atgataaata cgctgactac aataactttt
    13801 actctctcta tcttgtaaaa gaagaattgg ccaacagcta tgttattgat gctgacaatt
    13861 atctctttaa aaatatgttc cgcaatgatt tgacacgttc gacttatttt agtgtttatc
    13921 gtgaagattg taccaacgaa tggttcttgg tctatggaga tgactacaag gttcaagaca
    13981 ttattgttga tagcaaggca ggtcgcatcc ttagtggtgt atccttctgg gatgcttcaa
    14041 ctgcagaaaa gattgtcagc tttatcgaca aggcttatgc aagtggtgaa tttgttgatc
    14101 tctattggga caatatggtt aaggataata tcaaagagct agatgtctat gttgaagaat
    14161 tagaaggcaa tagcatttat gagatcgata gtgtccaaga ctatcgtaaa ttagaagaaa
    14221 ttcttaaaaa cgaaaattaa agattccaac atctgacaaa atagtcggat gtttttttga
    14281 ttttttacga acttttacga atagatagat gagtagaaaa agaaatggag ttatttatga
    14341 aaattacaaa ctatgaaatc tataagttaa aaaaatcagg tttgaccaat caacagattt
    14401 tgaaagtgct agaatacggt gaaaatgttg atcaggagct tttgttgggt gatattgcaa
    14461 atatatcagg ttgccgtaat ccagccgttt ttatggaacg ttattttcag atagacgatg
    14521 cgcatttgtc gaaagagttt caaaaatttc catctttctc tattttagat gactgttatc
    14581 cttgggattt gagtgaaata tatgatgcgc ctgtactttt attttacaag ggaaatcttg
    14641 acctcctgaa attcccgaag gtagcggtcg tgggcagtcg tgcttgtagc aaacagggag
    14701 ctaaatcagt tgaaaaagtc attcaaggct tggaaaatga actggttatt gtcagtggtc
    14761 tggccaaggg cattgacaca gcagctcata tggcagctct tcagaatggc ggaaaaacca
    14821 ttgcagtgat tggaacagga ctggatgtgt tttatcctaa agccaataaa cgcttgcaag
    14881 actacatcgg caatgaccat ctggttctaa gtgaatatgg acctggcgaa caacctctga
    14941 aatttcattt tcctgcccgt aatcgcatca ttgctggact ttgtcgtggt gtgattgtag
    15001 cagaggctaa gatgcgttca ggtagtctca ttacctgtga gcgagcaatg gaagaaggac
    15061 gcgatgtctt tgctattcct ggtagcattt tagatggact atcagacggt tgccatcatt
    15121 tgattcaaga aggagcaaaa ttggtcacca gtgggcaaga tgttcttgcg gaatttgaat
    15181 tttaaaaatg acctaagcta gaattctaag aaaaaatcaa ttttaagaga aaatgaaccc
    15241 aacatttcca taataaaacg catattagca agtttttaac acttgataat atgcgttttt
    15301 tctaagtgga ttagtagagt agaggatttt tctcatataa tactcttcga aaatctcttc
    15361 aaactacgtc agcttccatc tgcaacctca aaacagtatt ttgagctgac ttcgtcagtc
    15421 ttatctacaa cctcaaagca gtgctttgag caacctgtgg ctcgcttcct agtttgcgct
    15481 ttgattttca ttgagtataa gggaaagtat agtgaattga aataagatgt gaacaactct
    15541 atcaggaaag tcaaattgat ttatagaaat attttagcag ccaaggtgca ctgttataga
    15601 ttcaatacac tataatttag tgtaattgag aaaggagaaa tgattgtgat tgatgttggc
    15661 taggttatgt tcaatgattc ctaccgtctc aaatcttgtc agtaaggaaa aataaattct
    15721 tcaaaagtag agattacaag gcttgtttaa gaaagaattc aaagaccttg acaaataaaa
    15781 ataaaatggt tattataaaa aatggtctga aatagatgat gatacttttc gaaaatcttt
    15841 ttacgtcagc tcagctttgc cttgctgtgt tttgagcaag ctacggttag cttccgagtt
    15901 tgattttcat ttactagaaa tgaaactgat gagagatatc agtagacatc tgagttagga
    15961 tattatggaa aatgataaaa agagctcgtg agattggcat atcagactac taaagtattg
    16021 agtttgttag gattttagcg actagttagc tgggaaagga agatatttgt gacaaataat
    16081 aaactgtatt cgttgataga atttagaaat aaaatatatg aagaattaga actttccaga
    16141 agtgatttag cgattttact atgtgccatg cttatcgcct ctatcggatt aaatatggat
    16201 tcgactcccg tgattattgg agccatgtta atctctcctt tgatgacacc tattctggga
    16261 gtggggctct ctctagctat atttgatttt aaattgttaa gaaaatcttt taaaatatta
    16321 gctattcaaa ttcttgccag tctaatagct tcaacacttt atttttatct ttctcccatt
    16381 tcgtatgcta gttcggagat tgttgctaga acctctccga ctatttggga tgttctcatt
    16441 gcttttgtag gagggatagc aggtattatt ggtgctagga aaaaagagac caataatatt
    16501 gttcctggtg ttgctattgc aaccgccttg atgcctcctc tttgtacagt aggttatgct
    16561 attgcttctg ctaatctaaa atttatcata ggctcctctt acctattcct catcaattgt
    16621 agctttattg tcattgcgac ttatataggt gttaggttga tgatggttaa gaaacattat
    16681 tttaaagata atgaagaaga ctctaaaatg cgtaggattt tgcttctagt tgctgttttg
    16741 ctgatgattc cgagtttcat ctctgcaacg actttagtga gagaaacgtt gaaaaaagag
    16801 tcccttaaga aatttatatc agagcagttt caggggtata atattttgaa aaaaacctat
    16861 tctaaaaaga ctcataccct aaagctaacc atttcaggaa attatttgac agaagaagaa
    16921 ctcgatatga tttcaagtaa gagaggtgac tatggtttaa gtgatgtttc tgttcaagtt
    16981 tcacaattgt ctgattcaga acaacttagt aaggaagagc tggtggagta tttcttccag
    17041 tatatcaagg ataaggaagc aaaagaaaag gagaaagcta ataaatttga tacagagtct
    17101 gaggagcaat aatttcttga gaatagctgg tttctctcgt gagtcttcta tgtatatcaa
    17161 aggaagactg aggttttaag tataaaactt ttcttctatt atagtagcta agtcttgaca
    17221 gggttcaaaa aatggtttac actttataaa gtttattact ttgaaaaggt gtgatactgt
    17281 ggctacggca acaaaaaaga aaaaatcaac agttaaaaaa aatctagtca tcgtggagtc
    17341 gcctgctaag gccaagacga ttgaaaaata tctaggcaga aactacaagg ttttagccag
    17401 tgtcgggcat atccgtgatt tgaagaaatc cagtatgtcc gtcgatattg aaaataatta
    17461 tgaaccgcaa tatattaata tccgaggaaa aggccctctt atcaatgact tgaaaaaaga
    17521 agctaaaaaa gctaataaag tttttctcgc gagtgacccg gaccgtgaag gagaagcgat
    17581 ttcttggcat ttggcccata ttctcaactt ggatgaaaat gatgccaacc gtgtggtctt
    17641 caatgaaatc accaaggatg cagtcaaaaa tgcttttaaa gaacctcgta agatcgatat
    17701 ggacttggtc gatgcccaac aagctcgtcg gatcttggat cgcttggtag ggtattcgat
    17761 ttcgcctatt ttgtggaaga aggtcaagaa gggcttgtca gcaggtcgcg ttcagtccat
    17821 tgcccttaaa ctcatcattg accgtgaaaa tgaaatcaat gccttccagc cagaagaata
    17881 ctggacagtt gatgctgtct ttaaaaaggg aaccaaacaa tttcatgctt ccttctatgg
    17941 agtagatggt aaaaagatga aactgaccag caatgacgaa gtcaaggaag tcttgtctcg
    18001 tctgacgagt aaagactttt cagtagatca ggtggataag aaagagcgca agcgcaatgc
    18061 tcctttaccc tataccactt catctatgca gatggatgct gccaataaaa tcaatttccg
    18121 tactcgaaaa accatgatgg ttgcccaaca gctctatgaa ggaattaata tcggttctgg
    18181 tgttcaaggt ttgattacct atatgcgtac cgattcgact cgtatcagtc ctgtagcgca
    18241 aaatgaggcg gcaagcttca ttacggatcg ttttgatagt aagtattcta agcacggtag
    18301 caaggtcaaa aacgcatcag gtgctcagga tgcccatgag gctattcgtc cgtcaagtgt
    18361 ctttaataca ccagaaagca tcgctaagta tctggacaag gatcagctca agctatatac
    18421 ccttatctgg aatcgttttg tggctagcca gatgacagcg gccgtttttg ataccatggc
    18481 tgttaaattg tctcaaaaag gggttcaatt tgctgccaat ggtagtcagg ttaagtttga
    18541 tggttatctt gccatttata atgattctga caagaataag atgttaccgg acatggttgt
    18601 tggagatgtg gtcaaacagg tcaatagcaa accagagcaa catttcaccc aaccgcctgc
    18661 ccgttattct gaagcaacac tgattaaaac cttagaggaa aatggggttg gacgtccatc
    18721 aacctacgcg ccaaccattg aaaccattca gaaacgttat tatgttcgcc tggcagccaa
    18781 acgttttgaa ccgacagagt tgggagaaat tgtcaataag ctcatcgttg aatatttccc
    18841 agatatcgta aacgtgacct tcacagctga aatggaaggt aaactggatg atgtcgaagt
    18901 tggaaaagag cagtggcgac gggtcattga tgccttttac aaaccattct ctaaagaagt
    18961 tgccaaggct gaagaagaaa tggaaaaaat ccagattaag gatgaaccag ctggatttga
    19021 ctgtgaagtg tgtggcagtc caatggtcat taaacttggt cgttttggta aattctacgc
    19081 ttgtagcaat ttcccagatt gccgtcatac ccaagcaatc gtgaaagaga ttggtgttga
    19141 gtgtccaagc tgtcatcagg gacaaattat tgagcgaaaa accaagcgta atcgcctatt
    19201 ctatggttgc aatcgctatc cagaatgtga atttacctct tgggacaagc ctgttggtcg
    19261 tgactgtcca aaatgtggca acttcctcat ggagaaaaaa gtccgtggtg gtggcaagca
    19321 ggttgtttgt agcaaaggcg actacgagga agaaaagatt aaataagagg aggggcccga
    19381 aagtaaattt caggctcctt ttggttagaa cttgacaaaa tacatcattt tatgcgaaac
    19441 tagaagaaga ttattttata ctcaatgaga atcaaagagc aaattagaaa gctagtcgca
    19501 ggttgctcaa agcactactt tgaggttgaa gatggaagct gacctggttt gaagagattt
    19561 tcgaagagta ttaactagga gaagttatgc gtcttatcta tttgataatt ggttttttat
    19621 cactggcctt ggctattgtt ggggttgttt tacccttgtt gccgacaacg cctttccttt
    19681 tgttgtctat tgcttgtttc tccagaagtt ccaagcgttt cgaagactgg ctttatcata
    19741 ccaagctcta tcaaacatat gtagctgatt ttcgcgagac taagtctatt acgcgtgaac
    19801 gaaagaaaaa aatcatcgtc tctatctacg tcttgatggg aatttctatt tattttgcac
    19861 ctcttttacc agtcaaaatc ggtctgggtg ctttgaccat ctttatcact tattatctct
    19921 tcaaggtcat tccagacaaa gaatagttaa aacagtagtt atttgccttg ataaaattga
    19981 aatcatattc ataacaatat gatataataa atttgaagta atattcaagg agaatcaaat
    20041 gatttacgaa ttttgtgctg aaaatgtgac tttacttgaa aaggcgatgc aggctggagc
    20101 tcgtcggatt gaactctgtg ataatctagc agttggtggg acaacaccca gctatggagt
    20161 gactaaggca gcggttgaac tggcagctaa ctacgataca accatcatga ccatgattcg
    20221 gccacgtggt ggtgactttg tctataatga cctagaaatt gctatcatgc tagaagacat
    20281 tcgtttgact gctcaggctg gaagtcaagg ggttgtattt ggagctttaa ctgctgataa
    20341 aaagttggat aagcctaatc tggaaaagtt aattgctgca tcaaaaggaa tggaaattgt
    20401 ctttcacatg gcctttgatg aactaagtga tgaagatcaa ccggaagcta ttgactggct
    20461 cagtcaagcc ggtgtcactc gtatcctaac tcgtgctggt gtgtctggcg actccttaga
    20521 aaaacgtttt gttcactatc acagaatttt ggagtacgct aaaggtaaaa ttgaaattct
    20581 accaggtggg gggattgacc ttgaaaaccg tcaaaccttt atcgaccagg tgggggtaac
    20641 acaattgcat ggtactaagg ttgtttttta aaaaatagaa aggaactgct agctttgggt
    20701 agcagttttc acttatgttt gaaattttta aatcctatca atttaatcaa gaaaaggctc
    20761 atgattatgg ttttatagaa aatagcgaag tctggacata tagttgccag attttgcaag
    20821 gtgactttgt catgactgtg tccatcactg ctgataatgt gaactttcaa gtctttgacc
    20881 aagagactgg tgacctctat cctcacgttc atatggaaag catgagggga agttttgtcg
    20941 gaaatgtccg tgaggcttgt ctggagattc tttaccagat tcggaaggct tgttttgatg
    21001 tgcaagattt tatctgtcat cagactaagc gtatcatgac tcaagttcag gaaaagtatg
    21061 gaaaccagtt ggagtatctg tgggaaaaat cgcctgatac agctgtattg cgccatgaag
    21121 gcaatcaaaa gtggtatgcc gtcttgatga gaatctcttg gaataagctg gaaaagggta
    21181 gagaaggaca agtggaagca gtcaacctca agcatgacca agtagctaat ttgctttcac
    21241 aaaaggggat ttatccagcc tttcatatga gcaagcgcta ctggattagt gtgtcccttg
    21301 atgatacttt atcagatgaa gaagtactgg aattgataga aaaaagttgg aacttaacct
    21361 ataaaaaatg aaatatttta ataattttca tgaactttca attagctaaa tattctttac
    21421 tgaagaaatt ttcagaaaat ataggattta ccacaccaga ggaatatggt gccatcttca
    21481 aatacctgat tgagaatgtc aagacggatc gtcagatcat ctattcgcct cactgtcatg
    21541 atgacctcgg aatggcagtg gcaaatagcc ttgctgctgt caagaatggt gcaggacgtg
    21601 ttgaagggac tatcaatggt attagggagc gagctggaaa tgctgctttg gaagaaattg
    21661 cagtggctct caatattcgc caagattact accaagtaga aaccagtatt gtcctaaatg
    21721 agaccatcaa tacgtcagaa atggtttctc gcttctctgg tattccagtt cctaaaaaca
    21781 aagccgtcgt tggtggcaat accttctccc acgaatctgg tattcaccaa gatggagtcc
    21841 ttaaaaatcc tctcacttat gagatcatca cacctgaatt ggttggtgtt aagattccgc
    21901 ttggaaaatt atctggtcgc catgcttttg ttgagaaact gagagaattg gccctagatt
    21961 ttacagaaga ggatatcaaa ccactctttg ctaagttcaa ggcactggtc gataagaagc
    22021 aagaaatcac agatgcagat attcgagctt tggtagctgg aaccatggtt gaaaatccag
    22081 aaggcttcca ctttgatgat ttacaacttc aaactcatgc agataatgac attgaagcgc
    22141 tcgttagcct agccaatatg gatggtgaga aagtcgaatt taatgcgaca gggcaaggtt
    22201 ccgttgaagc aatctttaac gctatcgata agttctttaa ccaatctgtt cgtttggtgt
    22261 cctacactat cgatgcggta acagatggaa tcgataccca ggatcgggtt ttggtcactg
    22321 ttgaaaacag agatacagaa accatcttta atgcagcagg gcttgatttt gatgtgttga
    22381 aggcttctgc tattgtctat ataaacgcta atacctttgt tcaaaaagag aatgcaggtg
    22441 agatgggacg cagtgtttct taccacgata tgcctagtgt gtaaaggaga aggctatggc
    22501 aaagaaaata gtagctctag caggagacgg aattggccca gaaatcatgg aggttggttt
    22561 agaagttctg gaggctctag ctgaaaaaac aggttttgac tatgagattg acagacgacc
    22621 gttcggaggt gcagatattg atgcagcatg gcctccctta cctgatgaaa cccttaaggc
    22681 aagtagggaa gcagatgcta tcctactagc agctatcggt agtcctcagt atgatggagc
    22741 agtggttcgc cctgaacaag gcctgatggc tctccgtaag gaactcaatc tttacgctaa
    22801 tattcgtcct gtaaaaatct ttgacagtct aaagcatttg tcaccactca aactggaacg
    22861 aattgctggt gtagactttg tcgtggtgcg tgaattgaca ggcgggattt actttggaga
    22921 tcatattctt gaagagcgca atgcgcgtga tatcaacgac tatagctatg aggaagtgga
    22981 gcggattatt cgcaaagcct ttgaaattgc aagaaattgc agaaaaatcc ttactagtat
    23041 cgataagcaa aatgttctag cgacctcaaa actctggcgg aaagtagctg aggaagtcgc
    23101 acaggatttc tcagatgtaa ccttggaaca ccagctggta gactcagctg ctatgcttat
    23161 gattaccaat cctgctaagt ttgatgttat tgtaacggag aatctttttg gagatatttt
    23221 atctgatgaa tcaagcatct tatctggtac acttggggtt atgccatcag ccagtcattc
    23281 tgaaaatgga ccaagtctct atgaacctat tcacggttca gcacctgata ttgcaggtca
    23341 aggaattgcc aatcctattt ccatgatttt atcagttgtc atgatgttga gagatagttt
    23401 cggacgttat gaggatgcag agcgtatcaa acgtgctgtt gagacaagtc tggcggcagg
    23461 aattttaacg agagatatag gaggtcaggc ttcaacaaag gaaatgatgg aagctattat
    23521 tgcaaggtta tgaagttaga cgaaaaaatt actctagtcc ttttgatttg gaatgtcatc
    23581 attttcttga tttatggcat tgacaaattc aaggcaagaa gaagagcttg gcgcatccaa
    23641 gagaaaatct tactcatttt agcccttact tgtggtggtt ttggggcctg gttagctgga
    23701 atcacttttc accacaagac tcgaaaatgg tactttaaaa cagtttggtt tcttgggatg
    23761 gtgaccacac tagtagcctt atattttatt tggaggtaat ggatggcagg gtcttcgagg
    23821 gaacacgctg cttgggctct agcggactat ggttttaagg tcgtgattgc aggatctttc
    23881 ggtgacattc attacaataa tgaactcaat aatgacctgt tgccaatcgt tcagcctaga
    23941 gaggttagag agaaactagc ccagctaaaa ccaaccgacc aggtaactgt ggacttggaa
    24001 caacaaaaaa tcatctcacc agttgaagaa ttcaccttcg agatagatag cgagtggaaa
    24061 cataaactcc taaatagttt ggatgatatc ggtattacct tgcagtatga agagttgatt
    24121 gctgcttatg aaaaacaacg accagcctac tggcaggatt agaaaaaata gaaaaggaaa
    24181 tatagtaaac tgaaataaga tgtaaacaaa tgaattagag cttaacatcc atttccagca
    24241 attttttaga aactacagtg gactattctg gattcaacac attataaaat tatgacaaaa
    24301 cacattcaca agaaggctac gacattttaa aaggtgaggg cggatgtatc gtttgcccta
    24361 ctaaagttgg ttacattatc atgaccagtg acaaggcagg acttgagcgt aagttcgcag
    24421 ccaaagaacg taagcgtaac aaaccaggtg ttgttctctg cggtagcatg gatgaacttc
    24481 gcgctttagc gcaactcaac ccagaaattg aagcattcta ctaaaaacat tgggatgaag
    24541 atattcttct tggttgtatc cttccttgga aaccagaagc ctctgaaaaa ctcaaagcat
    24601 acggggatgg ccgtgaagaa cttatgactg atgtacgtgg tactagctgt tttgttatca
    24661 agtttggaaa agcaggtgaa caattggctg ccaagctttg ggaagaaggt aaaatggtct
    24721 acgcctcatc tgcttcaatg acaaaacgat tgaaactcgc tatgagagca aggtgtaatg
    24781 gtgtctatgg ttgataagga cggcaaactc atcccagaac aaggaggagc acgttcaact
    24841 tcaccagcac cagttgtgat ccgtaaaggg cttgacattg atatagtaaa atgaagtaag
    24901 agcaggacaa attaatcagg acagtcaaat cgatttctaa caatgtttta gaagtagagg
    24961 tgtactattc tagtttcaat ccactataaa atcatgatgc acctgtcaga tacttttaac
    25021 tcatgggact accgtcaggt tgagtattat taggatagag aagaagtcta gtgttaagga
    25081 cattacagct cataatacta ggctttttta tagaaattct tttctttttc tataggatat
    25141 ggtattctat gtagaaaata tatgttaata agtaatgcca atatttaaac atcattagta
    25201 aaaggagtta gattgatgaa taaaagaaaa gttagtttag aagattttta taaatggtat
    25261 agtctaaata aagaagagtt attaaataag gcaactgttg gtgaaaagtt taatgataaa
    25321 ttaaaagaag agtttctcca ggaatggcct ttggatagga ttttaacaat gtcaatcgat
    25381 gaatatgtaa taggaaaggg acagcaaaat aagtctttat gctacgctct tgagaaggga
    25441 aaatacaaaa atctatttct tggaatttct ggtggctcag cttcaaaatt tggtatttat
    25501 tggaataaaa aaacaaacaa atataaagat caagctaata atgagatttc agagttggat
    25561 cagcgatttt caaaattaaa atcagatttg tatgaaatta tcaaagaagg tattcgtttt
    25621 aactttgaaa atcctatttt tgatatgaaa agatcaacaa atgaatttat tggtcgttct
    25681 gctatggtga caaaattact ttgtatctat actgagggag atcctttctt tggtgtaaat
    25741 attaatagtc agaaagaatt ttggaaccac tttgtttctc agacaaatca aggtggacct
    25801 tatctgcaaa atcataaaat aattgaactg gtgtccaaaa cttatcctga gttggagcca
    25861 tcgaaattag gaactatgct ttttgagtat tctaagcttt ttatggaaaa taaggaagac
    25921 aatagtacaa tggattcatc aaacaatttt agtcatcaat taactcaatc tctattaaag
    25981 tctccaaacc ttatccttcg tggtgctcct ggcacaggaa agacttatct tgctaaagaa
    26041 attgccaaag aattaacgga tggcaacgaa gaccaaatcg gatttgtaca atttcaccca
    26101 tcctatgatt atacggattt tgtagaaggt ttaagaccag tatcaaatgg ggatggagct
    26161 attgagttta ggctacagga cggtattttt aaagattttt gtcagaaagc aaaagaaacc
    26221 caattgattg gaggacaaga taattttgat gaggcttggg attcttactt agaatatata
    26281 aatgttgctg aagaaaaaga atatataaca aaaacatctt acttatctgt taatagtaga
    26341 caaaatttgt cagtaaatta tgatagtggt gttccaggat ggtcactacc tagcaaatat
    26401 gtttacgagt tgtataaaga taaaaattat aataagcaag aatactacaa aagtggtgga
    26461 aaaactgtcc tagaaacatt gagaaagaga tttggtttga aagactatgt ttccccaaca
    26521 gaaattgata ctgataagaa attcgtcttc atcatcgatg aaatcaatcg tggggagatt
    26581 tctaagattt ttggcgaact ctttttctct atcgaccctg gctatcgtgg tgaaaaagga
    26641 agtgtttcta cccaatatgc aaatctacac gaaactgatg aaaagttcta tatccccgaa
    26701 aatgtttaca tcatcggaac tatgaatgat attgatcgtt cagtggatac ctttgatttt
    26761 gctatgcgtc gtcgttttcg ttttgttgaa gttactgccg agggtcaagt tggcatgttg
    26821 gataaagagc tgaatatcca tgcagaagaa gcaaaaattc gtctaagaaa cttgaacgct
    26881 gctatcgaaa atgttcagga attaaacagt cattatcata ttggaccaag ttattttctt
    26941 aagttgaagg atgtagattt tgactatgaa ttactctggt ctgattatat taagcctctc
    27001 ctagaagact acttgcgagg ttcttatgat gaggttgaaa ctttggaaac tttgaaaaaa
    27061 gcatttgaac tgacaaataa tgagcaaaaa gatcaggcag tagctgatga caatgaaagc
    27121 gatgaaaacg atgatgcgga ttactgataa tcaacacaag attattaaag aaaaatttgt
    27181 tgaagaatat cctaaactaa gcaatcttct tttagacaga accttggaaa gtctatccca
    27241 agatgaacgt attttcattt ttccaaatga tttgactcat actccagatt tggataagaa
    27301 acaaaagatt ttggaaacga tcaatcagga aatcaagaca ggaaatgtga ttggttttct
    27361 tggatatggt caggaaagat taacgatttc ctcacgattt tctgatgaga gtaatgacca
    27421 ttttttgcat tatctcttaa acaaggttct tcatatcaat ctcactagtt tagatgttgc
    27481 tttgtctcgt gaagagaggc tttatcaact tttgatgtat ctcttcccca agtatctaca
    27541 agctgctatt cgaaaaggtc tttataagga atatcatcga ttttctcata acgacagtca
    27601 tgttaaggga gtgattgatg taagaaacca tctcaagaaa aaccttcctt taacgggaaa
    27661 tattgcctac acaacgagag agttcaccta tgataatccc ctcatgcagt tgatttgtca
    27721 tactattgaa tacattaaga atcagaaaag cattgggcaa ggagttcttg atagtctctt
    27781 aactagtcgt gaaaatgtat ctgaaatcat gcgagtaact ccatcttata aactagctga
    27841 tcgtgcgaag attattcggg gaaataaatc taaacctata cgtcatgcat actttcacga
    27901 gtacagaaag ttacaagaac tttgtctgat gattctaaac caagaaaagc acggtttagg
    27961 ctatcaagat caaaaaattc atggtattct ttttgatgtt gcctggcttt gggaagagta
    28021 tgttcatact ttgttgccaa aagatttcat ccatccacga aataaagata agacggacgg
    28081 aatttcagta ttttctagtc gagaacgaaa agtttatcca gatttctata atagagattt
    28141 aaaaattgtg ttagacgcta aatataaaaa gcttgaagat actgaaaaag gaataaaccg
    28201 tgaggacttg ttccaactga tttcctattc ttatatttta aaagctgaga aggctggtct
    28261 tatttttccg agtgagaaaa aggcggttga taatgagata ggaaagctag cagggtacgg
    28321 agccttatta aagaaatggt ctattcaaat tcctcagaac tcttcatcct atcgtgaatt
    28381 ttgtgaaatg atggaaagat ccgaagaatc ttttaaaagg aatattacta aagaactggg
    28441 gagaaaataa tctctccgct ttcttttgtt attcatccaa taaaatccga acgatatatt
    28501 ttaatttata acattatttg acaaaaactt tactttagtt tataataaat taaggaaacg
    28561 tcggaaaaga cgtagagatg cgcaagcata tgtaggtcat tataaaagaa acgagacatc
    28621 gatatgttaa atgaatttcc aatttttgat tacgaagata ttcaattgat tccaaataaa
    28681 tgtgtgatta aaagccgtgc agaagcggat acaagtgtca ctctaggaaa tcacaccttt
    28741 aaactacctg ttgtgccagc taatatgcag acgattttgg atgaaaatgt agcagagcaa
    28801 ctggctaaag gtagttactt ctacattatg catcgttttg atgaggcagg acgtattcct
    28861 tttattaagc gtatgcatga gcaagggctc attgcgtcca tttctgttgg tgttaaggac
    28921 tatgagtatg atttcgttag ccagctcaag gatgatgctc cggaatatat cacgattgat
    28981 attgcccatg gtcatgcgga tagcgtgatt tctatgattc aacacatcaa gaaagaattg
    29041 ccagatacct ttgtcattgc tggaaatgtg ggaacaccag aagctgtgcg tgaattggaa
    29101 aatgctggtg cagatgctac taaggtcgga atcggtcctg gtaaggtttg tatcaccaag
    29161 gttaagactg gttttggtac aggtggttgg cagttggctg ctctacgctg gtgtgccaag
    29221 gctgcgcgta aaccgattat cgctgatgga ggaattcgta ctcacggtga tattgccaag
    29281 tctatccgct tcggtgctag catgatcatg attggttccc tctttgcagg acacattgaa
    29341 agtccaggga aaacgattga agtcgatggt gaacagttca aagaatatta tggttcagcc
    29401 tcacaatatc agaaaggtgc ttacaaaaat gtggaaggca aacgtatctt gcttcctgct
    29461 aaaggtcatc tgcaagacac tttaactgag atggaacaag accttcaaag tgctatttct
    29521 tatgcaggtg gacgtcaggt tgctgacctt aaacacgttg attatgtgat cgtgaaaaac
    29581 tccatctgga atggggatgc ttcccactaa gacggggtct ttgaccaaaa aacttgttat
    29641 tagagcaaat ttctgttata ataaaacaag tttccaccct tagtgtaatg gatatcacgt
    29701 aagattccgg ttcttgagat gggggttcga ttccctcagg gtggatgtaa acatcctaaa
    29761 aagcctttaa tagggctttt ttctttacac tgctttaaat ttgtccctaa tactcaatga
    29821 aaatcaaaga gcaaactagg aagctagccg taggctgctc aaagcactgc tttgaggttg
    29881 tagataagac tgacgaagtc agttacatat acctacggca aggcgaagct gacgtgattt
    29941 gaagagattt tcgaagagta taaaactgaa aatctctgtc taaagaattt ccaaatcccc
    30001 tccagtcccg ttttaaagtg actcaggggg cttttt
//
LOCUS       DAVDZK010000030        29000 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVDZK010000030 DAVDZK010000000
VERSION     DAVDZK010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29000
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.031"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            283..780
                     /locus_tag="VUX16_001503"
     CDS             283..780
                     /locus_tag="VUX16_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET8124445.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            780..2435
                     /gene="dnaX"
                     /locus_tag="VUX16_001504"
     CDS             780..2435
                     /gene="dnaX"
                     /locus_tag="VUX16_001504"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET8124446.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2463..2657
                     /locus_tag="VUX16_001505"
     CDS             2463..2657
                     /locus_tag="VUX16_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET8124447.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2807..3577
                     /gene="sufC"
                     /locus_tag="VUX16_001506"
     CDS             2807..3577
                     /gene="sufC"
                     /locus_tag="VUX16_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET8124448.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDMVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3605..4867
                     /gene="sufD"
                     /locus_tag="VUX16_001507"
     CDS             3605..4867
                     /gene="sufD"
                     /locus_tag="VUX16_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET8124449.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIESLELPVIERVKFH
                     RWNLGDGTITESEPSANVPDFTALDNHLKLVQVGTQTVFEQIPVELAQQGVVFTDFHS
                     ALEEIPELIEELFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEIKEPIEGVFYQDS
                     DSDVPFNKHIMIIAGKNSKISYLERLESRGEGSTKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQIQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4878..6104
                     /locus_tag="VUX16_001508"
     CDS             4878..6104
                     /locus_tag="VUX16_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET8124450.1"
                     /translation="MLDVEVIRKDFPILDQIVNDEPLVYLDNAATTQKPLAVLETINR
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     YAEEVLTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMVDLRAKLTD
                     KVQFVSLAHASNVLGVVNPIKEITQMAHQVGAIMVVDGAQSTPHMKIDVQDLDVDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MVGAIGLAAAVDYLEKIGMDAIEAHEQELIAYVFPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLDVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            6091..6531
                     /locus_tag="VUX16_001509"
     CDS             6091..6531
                     /locus_tag="VUX16_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET8124451.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFNAEDRLEDIAFLNSGCTISTASASMMTEAVLGKTKQEILELATIFSEMVQGQ
                     KDDRQDSLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6589..8001
                     /gene="sufB"
                     /locus_tag="VUX16_001510"
     CDS             6589..8001
                     /gene="sufB"
                     /locus_tag="VUX16_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET8124452.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEDVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDEVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFEKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANVGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSKVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8232..9473)
                     /locus_tag="VUX16_001511"
     CDS             complement(8232..9473)
                     /locus_tag="VUX16_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET8124453.1"
                     /translation="MKKIFLTLLTISLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLRDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLESMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVAHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9576..10685
                     /locus_tag="VUX16_001512"
     CDS             9576..10685
                     /locus_tag="VUX16_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET8124454.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVRVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11331..11678
                     /gene="ssrA"
                     /locus_tag="VUX16_001513"
     tmRNA           11331..11678
                     /gene="ssrA"
                     /locus_tag="VUX16_001513"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11848..11935)
                     /locus_tag="VUX16_001514"
     tRNA            complement(11848..11935)
                     /locus_tag="VUX16_001514"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11899..11901),aa:Ser,seq:gga)
     gene            12097..12837
                     /locus_tag="VUX16_001515"
     CDS             12097..12837
                     /locus_tag="VUX16_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET8124455.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQGIKEKTEVIEV"
     gene            12834..13745
                     /gene="pfkB"
                     /locus_tag="VUX16_001516"
     CDS             12834..13745
                     /gene="pfkB"
                     /locus_tag="VUX16_001516"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET8124456.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13742..15694
                     /locus_tag="VUX16_001517"
     CDS             13742..15694
                     /locus_tag="VUX16_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET8124457.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15858..18083
                     /locus_tag="VUX16_001518"
     CDS             15858..18083
                     /locus_tag="VUX16_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET8124458.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(18127..18555)
                     /locus_tag="VUX16_001519"
     CDS             complement(18127..18555)
                     /locus_tag="VUX16_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124459.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITATITIMN
                     ALDNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVKE
                     EKKEEQKTATQDSTTPATSKPATENEKQPNTPTSENKSNQ"
     gene            18693..19835
                     /locus_tag="VUX16_001520"
     CDS             18693..19835
                     /locus_tag="VUX16_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET8124460.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHLAVK
                     ESALWLKSQGFEVDFAPVDKKGFVDVEALADLIRPDTTLVSIVAVNNEIGSVQPIEAI
                     SELLADQPTISFHVDAVQALAKIPTEKYLTERVDCATFSGHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFIFSAEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19844..21058
                     /gene="thiI"
                     /locus_tag="VUX16_001521"
     CDS             19844..21058
                     /gene="thiI"
                     /locus_tag="VUX16_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET8124461.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVR
                     ADRDRAHAHLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            21194..22018
                     /locus_tag="VUX16_001522"
     CDS             21194..22018
                     /locus_tag="VUX16_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET8124462.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGHSWKIIPAIKRNSDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     KSPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            22040..22780
                     /locus_tag="VUX16_001523"
     CDS             22040..22780
                     /locus_tag="VUX16_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET8124463.1"
                     /translation="MHIEYLSHWSGHLNREMYLNRYGHAGIPVVVFASSGGSHNEYYD
                     FGMIDACTSFIEEGRVQFFTLSSVDGESWLATWKNAHDQAEMHRSYERYVIEEAIPFI
                     KHKTGWFDGMMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYYNDDAI
                     YQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDKKQIPAW
                     FAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            22793..23959
                     /locus_tag="VUX16_001524"
                     /pseudo
     CDS             22793..23959
                     /locus_tag="VUX16_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
     gene            24467..25432
                     /locus_tag="VUX16_001525"
     CDS             24467..25432
                     /locus_tag="VUX16_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET8124464.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDTV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLTNPPFKGSLDYNSTYNDLLATVKTKKQNYSFFLFSCEL"
     gene            25420..25959
                     /locus_tag="VUX16_001526"
                     /pseudo
     CDS             25420..25959
                     /locus_tag="VUX16_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819381.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            25972..26557
                     /locus_tag="VUX16_001527"
                     /pseudo
     CDS             25972..26557
                     /locus_tag="VUX16_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            26617..26853
                     /locus_tag="VUX16_001528"
     CDS             26617..26853
                     /locus_tag="VUX16_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HET8124465.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            26850..27263
                     /locus_tag="VUX16_001529"
     CDS             26850..27263
                     /locus_tag="VUX16_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET8124466.1"
                     /translation="MTIYLTEKQIEKINSLAIQRYSPNEKIQTVSPSALNMIVNLPEQ
                     FVFGKPLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            27381..28335
                     /locus_tag="VUX16_001530"
                     /pseudo
     CDS             27381..28335
                     /locus_tag="VUX16_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            28369..>29000
                     /locus_tag="VUX16_001531"
     CDS             28369..>29000
                     /locus_tag="VUX16_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET8124467.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIMVSYTNLREQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSE"
BASE COUNT         8780 a         5207 c         6331 g         8682 t
ORIGIN      
        1 ttgtgtgtat ctttattgat gatatctaga atcttgatgt ttgggtcttt aatatcgagc
       61 agttttgtga taaaatgtaa ttgttccata tgattctttc taatgagttg ttttgtcgct
      121 tttcattata ggtcatatgg gacttttttt ctacacaaaa ataggctcca taatatccat
      181 agggaattta cccactacaa atattataga gcccaaaatc ctttgtttac taaacaaggg
      241 atttttcttt tgtctctgct ccttttttga tataatagtt ctatgttaaa atcagaaaaa
      301 caatcacgtt atcaaatgtt aaatgaagaa ttgtccttcc tattggaagg cgaaaccaat
      361 gttttggcta atctttccaa cgccagtgct ctcataaaat cacgttttcc taataccgta
      421 tttgcaggct tttatttgtt cgatggaaag gaattggttt taggtccctt ccaaggaggt
      481 gtttcctgca tccgtattgc actaggcaag ggtgtttgtg gtgaggcagc tcactttcag
      541 gaaactgtta ttgttggaga tgtgacgacc tatctcaact atatttcttg tgatagtcta
      601 gctaaaagtg aaattgtggt gccgatgatg aagaatggtc agttacttgg agttctggat
      661 ctggattctt cagagattga ggattacgat gctatggatc gagattattt ggaacaattt
      721 gtcgctattt tgcttgaaaa gacagcatgg gactttacga tgtttgagga aaaatcttaa
      781 tgtatcaagc actttatcga aaatatagaa gtcaaaactt ctcccagtta gttggtcaag
      841 aagttgtggc taagactctt aaacaagcgg tggagcaaga gaaaataagt cacgcttatc
      901 ttttttctgg tcctcgtgga acgggaaaaa ccagtgttgc taaaatcttt gccaaggcta
      961 tgaactgtcc caatcaagtg ggtggcgaac cttgcaataa ctgctatatt tgtcaagcag
     1021 tgacggacgg tagtttagaa gatgtcattg aaatggatgc agcttctaat aatggggtag
     1081 atgaaattcg cgaaattcgt gataaatcta cctatgcgcc tagccttgct cgttataagg
     1141 tttatatcat agatgaggtt cacatgctgt ctacaggggc ttttaatgcc ctcctaaaga
     1201 cgctggaaga accaacacag aatgtagtct ttattttggc cactactgaa ttgcacaaga
     1261 ttcctgctac tattctatcc cgtgtgcaac gttttgagtt taaatcaatt aagacacagg
     1321 atattaagga acatattcac tatatcttag aaaaagaaaa tatcagttct gaaccagagg
     1381 ctgtggaaat cattgccaga cgggcggaag gtggaatgcg ggacgccttg tctattttgg
     1441 atcaagccct gagtttgaca cagggaaatg agctgacgac tgctatctct gaagaaatta
     1501 ctggcaccat tagcctatca gccttggatg attatgtggc ggccttgtct caacaggatg
     1561 ttcccaaagc tttgtcttgc ttgaatcttc tttttgacaa tggtaagagc atgactcgtt
     1621 ttgtgaccga tcttttgcac tatttaagag acttgttaat tgttcaaaca gggggagaaa
     1681 atactcatca tagttcagtc tttgtagaaa atttggcact tcctcaaaaa aatctgtttg
     1741 aaatgattcg cttagcaaca gtgagtttag cagatattaa gtctagtttg cagcccaaga
     1801 tttatgctga aatgatgacc gtccgtttgg cggaaatcaa gccagaacca gctctatcag
     1861 gagcggttga aaatgaaatt gctacgctga gacaggaagt tgcccgtctc aaacaagagc
     1921 tttctaatgt aggtgcggtt cctaaacaag ttgcaccagc tcctagtcga ccagctacgg
     1981 gcaaaacagt ctatcgtgtc gatcgtaata aagtgcaatc tatcttacaa gaggccgtcg
     2041 aaaatcctga tttagcacgt caaaatctaa ttcgtttgca gaatgcctgg ggagaggtaa
     2101 ttgaaagtct aggtgggccg gacaaggctc tgctagttgg ttctcaaccg gttgctgcca
     2161 atgaacacca tgctattctt gcttttgagt ctaacttcaa tgctggtcaa actatgaaac
     2221 gagacaatct caataccatg tttggtaata tcctcagtca ggcggcaggt ttttcacctg
     2281 agattttagc tatttccatg gaggaatgga aagaagttcg cgcagccttt tcagccaaag
     2341 ccaaatcttc tcaaactgaa aaagaagtag aagaaagcct gattccagaa ggatttgaat
     2401 ttttggctga taaagtgaag gtagaggaag actaaagaaa gatttcatga tacaataagt
     2461 ttatgaataa acaacaattt attattatgg cgctgtttac agctgctgag acctattttt
     2521 tcaatgaagc ctggatgact ggccgctata ttatggcagc cttttgggca attttactct
     2581 ttagaaattt ccgagtcagt tatgtgatgg gtaaaatcgt tgatgtcatc gatcagcatt
     2641 ttaataggaa agactagccc tcagcttcca gacaaaatca aagcctttta ggcttttttt
     2701 tgttatacta gaaaagtata tttatagaat ttttgctcta tttctgggga aatcagacgt
     2761 ttttctagta agtactgtaa aagttttgaa aaagaaagga actattatgt cagtaataga
     2821 gatcaaagat cttcacgttg agattgaagg aaaagaaatt ttaaaagggg ttaacctgac
     2881 cctgaaaaca ggagaaattg ccgctatcat gggaccaaat ggtacaggta aatcgactct
     2941 ttctgccgct atcatgggaa atccaaacta tgaagtaact aaaggtgaag ttttgtttga
     3001 tggcgtaaac atccttgagt tggaagtgga tgagcgtgcg cgtatgggac ttttccttgc
     3061 tatgcaatac ccatcagaaa tccctggaat taccaatgct gagtttcttc gtgccgctat
     3121 gaatgcgggt aaagaagatg atgagaagat ttcagttcgt gagtttatta ctaagctaga
     3181 tgaaaaaatg gaattgctca acatgaaaga agaaatggca gagcgttacc tcaacgaagg
     3241 cttctctggt ggtgagaaaa aacgcaatga aattcttcaa cttttgatgc tggagccaac
     3301 atttgctctt ttggacgaga ttgactcagg tcttgatatt gacgctctta aagttgtgtc
     3361 taaaggtgtc aatgccatgc gtggtgaagg ttttggtgct atgatcatta ctcactacca
     3421 acgtcttttg aactatatca cacctgatat ggtacacgtg atgatggaag gtcgtgttgt
     3481 cctttctggt ggtccagaat tggctgcgcg tttggaacgt gaaggatacg caaaattagc
     3541 tgaagaactt ggctacgact acaaggaaga attgtaattc cctcgtatct tttaggagaa
     3601 gtaaatgact agagaaaata ttaaactttt ttcagaaatg cacgctgaac caagctggtt
     3661 ggctgatctc cgtcaaaaag cttttgataa aatcgagagt ttggaattac cagttattga
     3721 gcgtgtgaaa tttcaccgtt ggaatctggg tgatggaacg attacagaaa gtgagccatc
     3781 agcaaatgtt ccagatttca ctgcactaga taatcacttg aagttggtgc aagtaggaac
     3841 tcaaactgtt tttgagcaaa ttccagttga gttggctcaa cagggtgttg tatttacaga
     3901 cttccattca gctttagaag aaattccaga gcttattgag gaattattca tgtcatctgt
     3961 caagtatgac gatgataagt tggcagccta ccatacagct tatttcaaca gtggtgctgt
     4021 tctttacatt cctgataatg ttgagattaa agaaccaatc gaaggtgttt tctaccaaga
     4081 cagtgatagc gatgtaccgt ttaacaagca tattatgatt atcgctggta aaaattctaa
     4141 gattagttat ctggagcgtt tagagtcacg tggtgaagga agtacaaaag caactgcaaa
     4201 catcactgtc gaagtgattg cacgttctgg tgctcaagtg aagtttgctg ccatcgaccg
     4261 tctaggtgaa aacgttactg cctacattag ccgtcgtggt aaattaggca atgatgcaag
     4321 cattgactgg gcaatcggtg tcatgaacga agggaacgtc gttgcggact ttgatagcga
     4381 cttgattgga aatggtagcc atgctgacct gaaagttgta gctctttcaa gtggccgtca
     4441 gatacaaggg attgataccc gagtgactaa ctatggttgc aactcaatcg gaaatatcct
     4501 tcaacatggg gttattcttg aaaaagcaac cttgaccttc aatggtattg gccacattat
     4561 caagggtgcc aagggagcag atgcgcaaca agaaagtcgt gttctcatgc tttcagacca
     4621 agcgcgttca gatgccaatc caattctttt gattgatgaa aatgacgtaa ctgcaggaca
     4681 tgcggcttct atcggtcagg tagatccaga agacatgtac tacctcatga gtcgtggttt
     4741 ggacaaggca actgcagagc gtttggttgt tcgtggtttc cttggatccg ttatcgttga
     4801 gattccagtc aaggaggttc gtgatgaaat gattgcgact atcgaagaaa aattgtcaaa
     4861 acgctaaggg gtagcctatg ttagatgtag aagtgattcg caaggatttt ccaattttag
     4921 accagattgt taatgatgaa ccattggttt atttggacaa tgctgcgacg acacaaaaac
     4981 cactagcagt tctggaaaca atcaaccgct actatgagca ggacaatgcc aatgttcatc
     5041 gtggcgttca taccttggca gaaagggcga cagcttctta tgaggcagct cgtgaaacca
     5101 ttcgtaagtt tatcaatgca gggtctacaa aggaagttct ctttactaga ggaacgacaa
     5161 ccagtcttaa ctgggtagcg cgttatgctg aggaagtctt gactgaggga gaccaggttt
     5221 tgatttctgt catggaacac cattctaata tcattccttg gcaggaagcc tgccgtaaga
     5281 ctggagcgga gcttgtctat gtttatctca aagacggagc tttggatatg gttgacttgc
     5341 gagcaaaatt gacggacaag gtacagtttg tttccctagc tcatgcctca aatgttctgg
     5401 gtgtggtcaa tccgatcaaa gaaatcactc aaatggccca ccaagtggga gccatcatgg
     5461 tggtggatgg tgctcagtct actcctcata tgaagattga tgttcaggac ttggatgtgg
     5521 acttctttgc cttttcaggt cacaagatgg ctggtccaac tggtatcggt gttctttacg
     5581 gcaaagaaaa gtatctggaa caaatgtcac cagttgaatt tggcggcgaa atgattgatt
     5641 tcgtttatga acaatctgct agttggaagg aattgccttg gaaattcgag gctggaactc
     5701 ctaacatggt tggtgcaatc ggacttgctg ctgcagttga ttatctggaa aagattggta
     5761 tggatgccat tgaagcccat gaacaggaat tgatcgccta tgtctttccg aaattacagg
     5821 cgattgaagg actgaccatt tatggttcac aggacttggc tcaacgttca ggtgtcattg
     5881 cttttaacct aggcgacctt catcctcacg accttgcaac ggctttggat tatgaaggtg
     5941 tggcagttcg tgcgggtcac cactgtgcgc aacccttgct ccagtatttg gatgttccag
     6001 caacagctcg tgcaagtttt tatatctaca ataccaaggc agattgcgac aagctagtcg
     6061 atgccttaca aaagacaaag gagtttttca atggcacttt ctaaactaga tagcctttat
     6121 atggcagtgg tagcagacca ttcgaaaaat ccacaccacc aagggaagtt ggaagatgct
     6181 gagcaaatca gtctcaacaa tccgacctgt ggcgatgtta tcaacctctc tgtcaagttt
     6241 aatgcagaag accgtttgga agatatcgct tttctaaact caggttgtac catctcaact
     6301 gcctctgcaa gcatgatgac agaggcagtt ttaggcaaga ccaagcaaga aattctagaa
     6361 cttgcaacca tcttttctga aatggttcaa ggacaaaaag atgacagaca agatagtctt
     6421 ggagatgcag ccttcttgtc aggtgttgct aaatttcctc aacgaatcaa gtgtgcgacc
     6481 ctagcttgga acgccctgaa gaaaacaatt gaaaatcaag aaaaacagta aggcaagttt
     6541 cttttgtctt atgaatcagt agaaatgaag aatgaaagaa aggatattat ggctgaagaa
     6601 agagtagaac caaaaccaat tgatcttggt gaatataaat ttggtttcca tgatgatgta
     6661 gagcctgtcc tatcgacagg aaaaggattg aatgaagatg tcattcgtga actatcagct
     6721 gccaagggag aacctgagtg gatgttagag ttccgtttga agtcttatga aacctttaaa
     6781 aaaatgccca tgcaaacttg gggagcagac ttgtcagaga ttgactttga tgacttgatc
     6841 tactaccaaa aaccatctga taaaccagct cgttcatggg atgaggttcc tgaaaaaatt
     6901 aaagaaacct ttgagcgtat cgggattcct gaagctgagc gtgcttatct agccggtgcc
     6961 tctgcccagt acgagtcaga agtggtttac cacaacatga aggaagaatt tgagaagtta
     7021 ggtattatct ttacagatac ggattctgcc ctcaaggaat acccagactt gtttaaacaa
     7081 tactttgcta agttggtacc gccaacagat aacaaattgg ctgcccttaa ctcagcagta
     7141 tggtctggtg gaacctttat ctacgtacca aaaggggtca aggtagatat tccacttcaa
     7201 acttacttcc gtatcaacaa cgagaataca ggtcagtttg aacgtacctt gattattgtt
     7261 gatgagggag caagtgtcca ctacgttgaa gggtgtacag cgccaacata ttcaagcaac
     7321 agcttgcacg ctgccatcgt agaaatcttt gccttggatg gtgcttatat gcgttataca
     7381 accatccaaa actggtctga taacgtttat aacttggtaa caaagcgtgc taaagctcaa
     7441 aaggatgcca ctgttgagtg gattgatggt aacttgggtg ccaaaacaac catgaaatac
     7501 ccatctgttt accttgatgg agaaggggcg cgtgggacta tgctttcgat tgcctttgct
     7561 aatgtagggc aacaccaaga tacgggtgct aagatgatcc acaatgctcc acatactagc
     7621 tcatctatcg tgtctaaatc catcgctaaa ggtggaggta aggttgatta ccgtggtcaa
     7681 gtaaccttta acaagaactc taagaaatct gtttctcaca ttgagtgtga taccattatc
     7741 atggatgact tgtcagcatc agataccatt ccgtttaatg aaatccacaa ctcgaaagtt
     7801 gctttggaac acgaagcaaa ggtttctaag atttcagaag agcaactcta ttacctcatg
     7861 agccgtggat tgtcagaatc tgaggcaact gagatgattg ttatgggatt tgtagagccc
     7921 tttacgaaag aacttccaat ggaatacgca gttgagctga accgcttgat tagctatgaa
     7981 atggaagggt cagttgggta aaatttgatt ttatactctt cgaaaatctc ttcaaaccac
     8041 gtcagcatcg ccttaccgta tgtatggtta ctgacttcgt cagtttcatc tacaacctca
     8101 aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt gttctttgat tttgagtatt
     8161 agatttactc aaaatcaagg attttgaaga tgaacttgta tcaaaaaatc gcggtttaaa
     8221 atcgcgattt tttataattt ctcgttaaca aagcggacaa actgattcca ccaaactttt
     8281 aagaaaaagg ctttttcaat tttcttgtct gctaccattt cgaaactagg gcgctctgtg
     8341 gtgatgtaac cttgaccaat caagtccttg tcttcataag tcaaatgggc aaccactgtt
     8401 ccagcttcaa gtggtgctgg gattgctttg gaatcaggtg tgaattgaac agattgggaa
     8461 gattgattcc caacacgttc gattagatag atatcctctg gagccactgc agttactgta
     8521 tcttcttttc catcttgtac aggggctttg ctatcttgat aggcatcgcc ttgttgaacg
     8581 attttgcgaa gtgtaaatgt agaagaaata taatccatta gggaagatgt agctgtaaat
     8641 cgagcgtaag gattattgtc ttgatgatct gcatttaaaa caactgtgat gactctcatg
     8701 cctttttcga cagtagtacc aacaaaagac tctccagcct tatctgttgt tcctgttttt
     8761 agcccatcaa aaccaccacg gtaagcaggc atactttcta acatgtagtt ggttgaagtg
     8821 attgtcattc cagcaaaagt agaagaaggt tttttggtga tttccaagac ttgtgggtat
     8881 tttttgatga ggttgcgagc aacaatagcg acatcataag cactaagctt attttcctca
     8941 tcttttttag aacctgggta aatgttatcc cttagagttt cattgttaag acctgtcgta
     9001 ttgacaacag tggcatcctg aattccccat tccaagagtt ttgcccgcat catatcgacg
     9061 aaatcttttt ctgagccagc aattttctca gctagggcaa tagcggcgct gttggcacta
     9121 gataccagag ttgcttcaag caactcttcg acagtataat tacgggcctc cataggaata
     9181 ttactggctt cagaatttgt cgtcaattga taaggataat cagaaatatc tacaggagtg
     9241 gagagggtaa tacttccgtt ttccaaagct tcatagacca gataaacagt aatcaatttt
     9301 gttatggaag caatttcgac aggttgcgtt gcatccttct catagagaat tttaccagta
     9361 tttgcctcaa cagcaatcgc atgtttagcg gcaatggtaa aatcttgagc aacagcagta
     9421 gaagcacccc ctaaaagaga gatagttaat aaagttaaaa atattttttt catagtagtc
     9481 ttattctatc ataaagaaaa aaaatattct tgctttaata attcatctgt taagcttttt
     9541 gaaaatatgg taaaataaag tgagggaggt aactcatgtt tcgtagaaat aaattatttt
     9601 tttggaccac agaaatttta ctcttaacca tcatctttta cctatggaga cagatggggt
     9661 ctttgattaa cccttttgtt agagtgctta atacaattat gattccattt ttattagggg
     9721 gctttcttta ttatttgaca aaccctattg ttactttctt aaataaagtc tgtaaactca
     9781 atcgtttgct tggtatttta attaccttgt gtactttggt ctggggaatg gtcataggtg
     9841 ttgtctatct cttacctatt ttgattaatc agttatctag tttgattata tctagtcaaa
     9901 ctatttatag tcgagtacaa gacttaatca tagacttatc taattatcct gcgctccaga
     9961 atttggatgt agaagctaca attcagcagt taaacttatc ctatgttgat attcttcaaa
    10021 atatcctaaa tagcgtatca aatagtgtgg ggagcgtctt gtcagctctt atcagtactg
    10081 ttttgatttt gattatgact ccagtttttt tggtttattt cttattagat ggacataaat
    10141 tcttgcccat gcttgaaaga acaattctaa agagggatcg cttgcatatt gcaggcttat
    10201 taaagaattt aaatgcgacg attgctcgct atattagtgg agtttcgatt gacgcaatca
    10261 ttataggttg tttggcttat attggctata gtattattgg tttaaaatat gctttagttt
    10321 ttgccatttt ttctggtgta gccaatttaa ttccttatgt gggaccaagt attggtttga
    10381 ttcctatgat catcgcaaat atattcactg atccccatag actgctgatt gcagtgattt
    10441 atatgcttgt tgttcagcag gtagatggca atatcttata tcctcgaatc gtaggaagtg
    10501 ttatgaaggt tcatccaatc acgattttag ttttactttt gttgtcaagc aatatctatg
    10561 gtgtagttgg aatgattgtc gcagtgccaa cctattctat cttgaaagaa atttctaagt
    10621 tcttatcccg tttgtatgaa aatcataaaa taatgaaaga acgagaaaga gaattagcta
    10681 agtaaaagtc aggagaaccc tgatttttct ttactggaag tggcctttag attagaagac
    10741 tgaaaataag ttaaagtctt aaactaattt tcacagctaa gaatagtaga agttaatctg
    10801 ataaaaatcg aaaaaaccag tggaattccg tgtcagggta agttccactg gttttcatag
    10861 tctattaaag ttcgaatgaa acctatttat agtatattga aactagaata gtacacctct
    10921 aattctaaaa cattgttaga aatcgatttg actgtcctga tctattcgtc ctattcttat
    10981 ttcattttac tatattttgg tgcaataagt gaaaagtagt ccgaataata taaggattaa
    11041 ttttatagtt tttaaactca aatgaattaa aataaagaga gtacgaaaat tctcatctga
    11101 aagtatttta gaataattct cttcgtgaat ttcttcaaaa cagatagctt catcttaggt
    11161 atgtgttaat tggatttcgt aagctctatt tacaatcgta aagttatgca ctgagaaagt
    11221 tgtagttagt cttccagttt gctaaatttc tcgaatagta tcttttttag gtatgtgatt
    11281 tctttttgca tttttgagtt agataaggta taatggtttt attgtctttt ggggtcgtta
    11341 cggattcgac aggcattatg aggcatattt tgcgactcgt gtggcgacgt aaacgctcag
    11401 ttaaatataa ctgcaaaaaa taacacttct tacgctctag ctgcctaaaa accagcaggc
    11461 gtgacccgat ttggattgct cgtgttcaat gacaggtctt attattagcg agatacgatt
    11521 aagccttgtc tagcggcttg ataagagatt gatagactcg cagtttctag gcttgagtta
    11581 tgtgtcgagg ggctgttaaa ataatacata acctatggtt gtagacaaat atgttggcag
    11641 gtgtttggac gtgggttcga ctcccaccgg ctccattatt cctttgcatt cttttgcatt
    11701 ccttggtaaa acgttgttaa atcaacgttt tttattttta tctttggtat tcctttgcat
    11761 tcttttgcta aaaagggagt cacaaacaga ccctatttta aaaaaggata caacatttgt
    11821 tgcatcctaa aaataatctt ttttcgacgg aagatatggg attcgaaccc acgcacgcta
    11881 ttacacgcct accgcgtttc caacacggcc tcttaagcct cttgagtaat cttccaatac
    11941 ttactcaaat agtctaccat aaaggctctt atcttgcaat aaaaattcta gaaataagaa
    12001 aaatgataga ttttgaaaga aaatgataaa aaatgcttga cttcaaaata aagtatggta
    12061 gaatgaatag tgtaaacgat aacaggaggt gattcagtgt taaaaacaga acgtaaacaa
    12121 ctgattttag aggagttaaa tcaacatcat gtagtttctc tagaaaaatt agttagtttg
    12181 ctagaaactt cagaatcaac ggttcgaaga gacttggatg agttggaagc ggaaaacaag
    12241 cttcgtcgtg tgcatggtgg agcagaactc ccccactcct tacaggaaga agaaaccatt
    12301 caagaaaaat ctgtcaaaaa ccttcaagaa aagaagttgc tggctcagaa agcagcctct
    12361 ctcattaaag aaaaagatgt catctttatc gatgctggaa caacaactgc ttttttgatt
    12421 catgaattgg tcaataagaa tgttacagtt gtgaccaact ccattcacca tgccgctcag
    12481 ttggttgaaa agcagattcc aactgtcatg gttggaggaa acgtcaagac ggcgacagat
    12541 gctagtatcg gtggcgttgc tcttaaccag attaaccaat tgcactttga ccgtgccttt
    12601 atcggaatga atggtgttga cgatggctat tatacgactc ctgatatgga ggagggagct
    12661 gtgaaaagag ctattttgga gaatgccaag cagacctacg tcttggtgga ttcgtcaaaa
    12721 attggacaaa cttgctttgc caaggtagca ccactcaaac gcgctatcgt tatcactagt
    12781 caagggcatg agctcttgca gggtattaag gagaaaacgg aggtaataga agtatgattt
    12841 atacagtcac actcaatcca tccattgact atatcgttcg tttggaccaa gtcaaagttg
    12901 gtagtgtaaa tcgtatggac agtgatgata agtttgctgg tgggaaagga atcaatgtca
    12961 gccgtgtctt gaaacgtttg aatataccaa atacagcgac gggatttatc ggtggcttta
    13021 ctggtaaatt tatcacagat actttagcag aggaagaaat cgagacacgt tttgtccagg
    13081 tggcagaaga tactcgtatc aatgttaaaa tcaaagcaga ccaagaaaca gaaatcaacg
    13141 gaacgggtcc aactgttgaa ccggttcagc tagaagaatt gaaagctatt ttatctagtc
    13201 tgacagcaga agatacagtt gtctttgcag gttcaagtgc taaaaatcta ggcaatgtta
    13261 tctataagga tttgatttcc ttgacgcgcc agactggtgc gcaagtggtc tgtgactttg
    13321 aaggacagac cttaattgat agtttggact accagcctct tcttgtaaaa ccaaacaatc
    13381 atgaacttgg agcgattttt ggggttaaac tcgaaagttt agatgaaatt gagaaatacg
    13441 ctcgtgagtt actggctaag ggtgctcaaa atgttattat ctctatggct ggtgatggcg
    13501 cccttcttgt cacatctgag ggagcttact tcgctaaacc aatcaaagga acagtcaaaa
    13561 attcagttgg agctggtgat tctatggttg ctggattcac aggtgaattt gtcaaatcaa
    13621 aagacgcagt agaagccttc aaatggggag tggcttgcgg aacggcaact accttctcag
    13681 atgacttggc aacggcggaa tttattaaag aaacatatgg aaaagttgag gtagaaaaaa
    13741 gatgaaaatt caagacctat tgagaaaaga tgtcatgttg ctagatttgc aggcaactga
    13801 aaaaacagct gtcatcgacg agatgattaa aaatttgaca gagcacggtt atgtaacaga
    13861 ttttgaaaca tttaaagaag gaattttggc gcgtgaagct ttgacttcta ctggtttggg
    13921 tgatggaatc gcaatgcctc acagcaaaaa cgctgctgtc aaagaagcga cagttctatt
    13981 tgctaagtca aataagggtg ttgactacga gagcttggat ggacaagcaa ctgacctctt
    14041 cttcatgatt gcagctccag aaggtgccaa tgatactcac ttggcagcct tggcagaatt
    14101 gtctcaatac ttgatgaaag acggttttgc agacaaactt cgtcaagcaa catctgcaga
    14161 ccaagttatc gaactttttg accaagcttc agaaaaaact gaggaacttg ttcaagcacc
    14221 tgctaatgac tctggtgact ttatcgtagc tgttacagct tgtacaacag gtattgccca
    14281 cacttacatg gcccaagaag cccttcaaaa agtagctgct gaaatggggg ttggtatcaa
    14341 ggtcgaaacc aacggtgcta gcggtgttgg aaatcaacta actgcagaag atatccgtaa
    14401 ggctaaagct attatcattg cagcagacaa ggccgttgaa atggatcgat ttgatggaaa
    14461 accattgatc aatcgtccag ttgctgacgg tatccgtaag acagaagagt taattaactt
    14521 ggctctttca ggagatactg aagtctaccg tgccgctaat ggtgcaaaag ctgcaacagc
    14581 ctctaacgaa aaacaaagcc ttggtggtgc cttctacaaa cacttgatga gtggtgtatc
    14641 tcaaatgtta ccattcgtta tcggtggtgg tatcatgatt gcccttgcct tcttgattga
    14701 cggtgctttg ggtgttccaa atgaaaacct tggcaatctt ggttcttacc atgagttagc
    14761 ttctatgttc atgaaaattg gtggagctgc ctttggtttg atgctgccag tctttgcggg
    14821 ttatgttgcc tactctattg ctgaaaaacc aggtttggta gcaggtttcg tggctggtgc
    14881 tattgccaaa gaaggttttg cctttggtaa aattccttat gccgcaggtg gtgaagcaac
    14941 ttcaactctt gcaggtgtct catctggttt cctaggtgcc cttgttggtg gatttatcgc
    15001 aggtgccttg gttcttgcca tcaagaaata cgttaaagtt cctcgttcac tcgaaggtgc
    15061 taaatcaatc cttctattgc cacttcttgg aacaatcttg acaggatttg ttatgctagc
    15121 tgtaaatatc ccaatggctg caatcaatac tgctatgaat gacttcctag gcggtcttgg
    15181 aggaggttca gctgtccttc ttggtatcgt ccttggtgga atgatggctg ttgacatggg
    15241 tggaccagtt aataaagcag cttatgtctt tggtacaggt acgcttgcag caactgtttc
    15301 ttcaggtggt tctgtagcca tggcagcagt tatggctgga ggaatggtgc caccacttgc
    15361 aatctttgtc gcaactcttc ttttcaaaga taaatttact aaggaagaac gtaactctgg
    15421 tttgacaaac atcatcatgg gcttgtcatt tatcactgag ggagcgattc catttggtgc
    15481 cgctgaccca gctcgtgcga ttccaagctt catccttggt tcagcagtag caggtggact
    15541 cgttggtctt actggtatca aactcatggc gccacacgga ggaatcttcg ttatcgccct
    15601 tacttcaaat gctctccttt acctcgtttc tgtcttggta ggagcaatcg taagtggtgt
    15661 ggtttatggt tacctacgca aaccacaagc ataaaaaata gaaaaatgaa aagattggac
    15721 cgtttggtgc agtctttttc tcttcccgaa atgcctgtga aatatggtat aatagaagaa
    15781 tggcaaacaa gaatacaagt acaacaagac ggagaccgtc taaagcagaa ctggaaagaa
    15841 aagaagcgat tcaacgaatg ttgatttcgt taggaattgc gattttattg attttcgcag
    15901 ccttcaaatt aggggctgca ggtataaccc tttataattt aattcgcttg ctagtgggta
    15961 gcctagctta tctggcgata ttcggcctat taatctatct cttctttttc aagtggatac
    16021 gaaaacagga aggactctta tctggctttt tcaccatatt tgctggctta ctcttgattt
    16081 ttgaggccta cttggtttgg aaatatggtt tggacaagtc cgttctaaaa gggaccatgg
    16141 ctcaggttgt gacagatctg actggttttc gaacgactag ctttgctgga gggggcttga
    16201 tcggggtcgc tctttatatt ccaacagcct ttctcttttc aaatatcgga acttacttta
    16261 ttggttctat cttgatttta gtgggttctc tcctagtcag cccttggtct gtttacgata
    16321 ttgctgaatt tttcagtaga ggctttgcca aatggtggga agggcacgag cgtcgaaaag
    16381 aggaacgctt tgtcaaacaa gaagaaaaag ctcgccaaaa ggctgagaaa gaggctagat
    16441 tagaacaaga agagactgaa aaagccttac tcgatttgcc tcctgttgat atggaaacgg
    16501 gtgaaattct gacagaggaa gctgttcaaa atcttccacc tattccagaa gaaaagtggg
    16561 tggaaccaga aatcatcctg cctcaagctg aacttaaatt ccctgaacag gaagatgact
    16621 cagatgacga agatgttcag gtcgattttt cagccaaaga agcccttgaa tacaaacttc
    16681 caagcttaca actctttgca ccagataaac caaaagatca gtctaaagag aagaaaattg
    16741 tcagagaaaa tatcaaaatc ttagaagcaa cctttgctag ctttggtatt aaggtaacag
    16801 ttgaacgggc cgaaattggg ccatcagtga ccaagtatga agtcaagccg gctgttggtg
    16861 taagggtcaa ccgcatttcc aatctatcag atgacctcgc tctagccttg gctgccaaag
    16921 atgtccggat tgaagcacca atccctggga aatccctaat cggaattgaa gtgcccaact
    16981 ccgatattgc cactgtatct ttccgagaac tatgggaaca atcgcaaacg aaagcagaaa
    17041 atttcttgga aattccttta gggaaggctg ttaatggaac cgcaagagct tttgaccttt
    17101 ctaaaatgcc ccacttgcta gttgcaggtt caacgggttc agggaagtca gtagcagtta
    17161 acggcattat tgctagcatt ctcatgaagg cgagaccaga tcaagttaaa tttatgatgg
    17221 tcgatcccaa gatggttgag ttatctgttt acaatgatat tccccacctc ttgattccag
    17281 tcgtgaccaa tccacgcaaa gccagcaagg ctctgcaaaa ggttgtggat gaaatggaaa
    17341 accgttatga actctttgcc aaggtgggag ttcggaatat tgcaggtttt aatgccaagg
    17401 tagaagagtt caattcccag tctgagtaca agcaaattcc gctaccattc attgtcgtga
    17461 ttgtggatga gttggctgac ctcatgatgg tggccagcaa ggaagtggaa gatgctatca
    17521 tccgtcttgg gcagaaggcg cgtgctgcag gtatccacat gattcttgca actcagcgtc
    17581 catctgttga tgtcatctct ggtttgatta aggccaatgt tccatctcgt gtagcatttg
    17641 cggtttcatc aggaacagac tcccgtacga ttttggatga aaatggagca gaaaaacttc
    17701 ttggtcgagg agacatgctc tttaaaccaa ttgatgaaaa tcatccagtt cgtctccaag
    17761 gctcctttat ctcggatgac gatgttgagc gcattgtgaa cttcatcaag actcaggcag
    17821 atgcagacta cgatgagagt tttgatccag gtgaggtttc tgaaaatgaa ggagaatttt
    17881 cggatggaga tgctggtggt gatccgcttt ttgaagaagc taagtctttg gttatcgaaa
    17941 cacagaaagc cagtgcatcc atgattcagc gtcgtttgtc agttggattt aaccgtgcga
    18001 cccgtctcat ggaagagctt gagatggcag gtgtcattgg tccagctgaa ggtaccaagc
    18061 caagaaaagt attgcagcaa taaaaaatag cttctttcca aggttggaag gaagctattt
    18121 ttctggttat tgattacttt tattttctga agttggagta ttgggctgtt tttcattttc
    18181 agtggcaggt ttacttgtag caggtgtagt agagtcctga gttgctgttt tctgctcttc
    18241 ttttttctct tccttgacgc tagattttgg cgtttcttct tgttgtgttt tttcttgaga
    18301 agtgttattt tccttatttg gagtagtatt ttcctgaggg gattcttttt gaatttcttt
    18361 gacaaaggtt gtcgtctggc ttgtcgtagg ttcttttttg gtatttttat tattatccaa
    18421 ggcattcatg atcgtgatag tcgcagtaat caagccgagg atactaccga tagtagtaat
    18481 ggttttttga aaaacagtaa agcctttttt gatatgttct gttttcggtt ttgaagttct
    18541 acgataatta gacatgcatt ctctcctttg attatgactt attatactct gtttctttaa
    18601 aaaaatctta aaaaaagaga aattgccctt tcttgtcgca agctctgttt catgatacaa
    18661 tagagggagt gattttagaa agcgtgagaa acatgattta ctttgataat tcagcgacga
    18721 ccaagcctta tcctgaagcc cttgaaacct atatgcaggt cgcttcaaaa attttaggaa
    18781 acccatctag tctccatcgt ttgggagacc aagcaacacg aatattagat gcttctcgcc
    18841 aacagattgc agatttaatc ggtaagaaaa gcgatgaaat cttctttacc tctggtggaa
    18901 cagaagggga taactgggtt atcaagggtg tggcctttga aaaagctcag tttggcaagc
    18961 acatcattgt ttcagccatt gaacatctag cagtcaaaga gtcagccctc tggttgaaaa
    19021 gtcaaggatt tgaagtggat tttgctcccg ttgataagaa aggctttgtc gatgttgagg
    19081 cgttagcaga tttgatacgt cctgatacga ccctcgtttc catcgtggca gttaacaatg
    19141 aaattggctc tgttcagccc attgaggcta tttcagaatt gttggcagat cagccgacta
    19201 tttctttcca cgttgatgcg gttcaggcgc ttgccaagat tccgactgaa aagtatctga
    19261 cagaacgggt ggattgcgcg actttctctg gtcacaagtt ccacggagtt cgtggtgttg
    19321 gttttgtcta tatcaagtct ggcaagaaga ttacgcctct tttaacaggt ggtggtcagg
    19381 agcgcgacta tcgttcgaca actgaaaatg tggcagggat tgcagcgaca gccaaggctc
    19441 tgcgtttgtc tatggaaaaa ctggatatct ttaggagtaa gacagggcag atgaaggcag
    19501 tgattcgcca agctctttta gattatccag atatatttat cttttcagct gaggaagact
    19561 ttgcccctca tatcctgact tttggaatca agggtgttcg tggtgaagtc atcgttcacg
    19621 cctttgaaga ctatgatatt ttcatctcaa caacctctgc ttgttcgtcc aaggctggga
    19681 aacctgcagg taccttgatt gccatgggag tggataagga taaggcccag tcagctgtgc
    19741 gtcttagtct agaccttgaa aatgatatga gtcaggtcga gcagtttttg accaagttaa
    19801 aattgattta caatcaaact agaaaagtaa gataggagca ttcatgcagt attcagaaat
    19861 tatgattcgc tacggtgagc tgtcaaccaa gggtaaaaac cgtatgcgtt tcatcaataa
    19921 acttcgcaat aatatttcag acgttttgtc tatctatccc caagttaagg taagggcaga
    19981 tcgcgaccgt gcccacgctc acctcaatgg agcagattac acagcagtag cagaatcgct
    20041 caaacaagta tttggaattc agaatttttc tcctgtttat aaggttgaaa aatctgtaga
    20101 agttttgaag tcttctgtcc aagagattat gcgggacatc tacaaggaag gtatgacctt
    20161 taagatttct agcaagcgta gcgaccacaa ctttgaactt gatagtcgtg aactcaacca
    20221 aacacttgga ggggctgtat tcgaagccat tccaaatgtg caagttcaaa tgaaaagtcc
    20281 tgacatcaat cttcaggtgg agattcgtga agaagcagcc tatctttctt atgaaaccat
    20341 tcgtggggct ggtggtttgc cagttggaac ttcaggtaaa gggatgctca tgttgtcagg
    20401 agggattgac tcacctgtag caggttatct tgctcttaag cgtggggtgg atatcgaggc
    20461 agttcacttt gctagtccac catatactag tcctggtgcc ctcaagaaag cgcaggactt
    20521 gacccgtaaa ttgaccaagt ttggcggaaa tatccagttt attgaggtgc ctttcacaga
    20581 gattcaagag gaaatcaaag ccaaagcgcc agaagcttat ttgatgactc taactcgtcg
    20641 ctttatgatg cggattactg accgtattcg tgaggtacga aatggtttgg ttatcatcaa
    20701 tggggaaagt ctaggtcaag tagccagcca aacccttgaa agtatgaagg ctatcaatgc
    20761 tgttaccaac actcccatca ttcgtcctgt ggttaccatg gacaagttgg aaatcattga
    20821 catcgcccag gaaatcgata cctttgacat ttcaatccaa ccgtttgaag actgttgtac
    20881 catttttgca ccagatcgtc caaaaacaaa tcctaaaatt aagaatgcgg agcagtacga
    20941 agcgcgtatg gatgttgaag gcttggttga gcgagcagtg gctggaatca tgattactga
    21001 aatcacacct caagccgaaa aagatgaagt tgatgacttg attgacaatc tgctctaatt
    21061 cagaaaatcc aaaagaatag cgaaaatcag taaaaaaagt tagttttttc tctaaaaaca
    21121 ggtaaaaaac taactttttt ctatttttat gatataatga tataaaattt tgaatataga
    21181 gagttttctg acaatgaatc aatcctactt ttatctaaaa atgaaagaac acaaactcaa
    21241 ggttccttat acaggtaagg agcgccgtgt acgtattctt cttcctaaag attatgagaa
    21301 agatacagac cgttcctatc ctgttgtata ctttcatgac gggcaaaatg ttttttatag
    21361 caaagagtct ttcattggac attcatggaa gattatccca gctatcaaac gaaattcgga
    21421 tatcagtcgc atgattgtcg ttgctattga caatgatggt atggggcgga tgaatgagta
    21481 tgcggcttgg aagttccaaa aatctcctat cccagggcag cagtttggtg gtaagggtgt
    21541 ggagtatgct gagtttgtca tggaggtggt caagcctttt atcgatgaga cctatcgtac
    21601 aaaagcagac tgccagcata cggctatgat tggttcctca ctaggaggca atattaccca
    21661 gtttatcggt ttggaatacc aagaccaaat tggttgcttg ggcgtttttt catctgcaaa
    21721 ctggctccac caagaagcct ttaaccgcta tatcgagtgc cagaaactat cgcctgacca
    21781 gcgcatcttc atctatgtag gaacagaaga agcagatgat acagacaaga ccttgatgga
    21841 tggcaatatc aaacaagcct acatcgactc gtcgctttgc tattaccatg atttgatagc
    21901 agggggagta catctggata atcttgtgct aaaagttcag tctggtgcca tccatagtga
    21961 aatcccttgg tcagaaaatt taccagattg tctgagattt tttgcagaaa aatggtaagt
    22021 taagaaagaa aaaaacgaaa tgcatattga atatcttagc cactggagtg gtcatcttaa
    22081 ccgtgaaatg taccttaacc gttatggaca tgctgggatt ccagttgtgg tctttgcttc
    22141 atcaggtggt agtcacaacg aatactatga ttttggcatg attgatgcct gcacttcctt
    22201 tatcgaggaa ggccgtgtcc agttctttac cctatctagt gtggatggtg agagctggtt
    22261 ggctacttgg aaaaatgctc atgaccaagc ggaaatgcac cgttcctacg aacgttatgt
    22321 gattgaggag gccattcctt ttatcaagca caagacaggt tggtttgatg gcatgatgac
    22381 gacaggttgc tctatgggag cctatcatgc actcaatttc ttcctccagc atccagatgt
    22441 ctttaccaaa gtgattgctc tcagtggtgt ttacgacgca cgtttctttg tcggtgatta
    22501 ctacaacgat gatgctattt accaaaactc gccagtagat tatatttgga accaaaacga
    22561 cggctggttt attgaccgtt accgtcaggc agagattgtg ctgtgtacgg ggcttggagc
    22621 ctgggaacaa gatggtttgc catcctttta caagctcaaa gaagcctttg acaagaaaca
    22681 aattccagcc tggtttgctg aatggggaca tgatgtcgcc catgactggg aatggtggcg
    22741 taaacaaatg ccttatttcc tcggtaatct ctatttataa aaggagttac ctatgaatta
    22801 ccttgttatt tctccctact atccacaaaa ctttcaacag tttaccatcg aactagctaa
    22861 taaaggcatc acagtcttgg gaattggtca agagtcttac gagcaattgg atgagccctt
    22921 gcgcaatagc ttgatcgagt attttcgtgt tgataatctt gagaacatag atgaagtcaa
    22981 acgtgcagtt gcttttctct tttataaaca tggtccaatt gaccgcatcg agtctcacaa
    23041 tgaatactgg cttgagctag acgcaacact cagagaataa ttcaatgttt ttggtgccaa
    23101 accagaggat ctcaaaaaga cgaaatataa gtctgaaatg aagaaacttt tcaaaaaagc
    23161 aggtgttcct gtggtacctg gagctgttat caagacggaa gcagatgttg atcaagcagt
    23221 gaaggaaatc ggtcttccaa tgattgccaa acctgataat ggagtgggag cagccgcaac
    23281 ctttaaactt gagacagaag acgatatcaa tcacttcaag caagaatggg accattcaac
    23341 cctttatttc tttgaaaaat ttgtcacttc cagcgaaatc tgtacctttg acgggctcgt
    23401 ggacaaggat ggaaagattg tcttctcaac aacctttgac tacgcctata caccacttga
    23461 cctcatgatt tataagatgg acaattctta ttatgtgctc aaggatatgg atcctaaact
    23521 gcgcaagtat ggggaagcaa ttgtcaaaga atttggtatg aaagaacggt ttttccatat
    23581 tgagttcttc cgtgaggggg acgattatat taccatcgag tacaataacc gccctgcagg
    23641 tggttttacc attgatgttt ataactttgc tcattccttg aacctttatc gtggctatgc
    23701 agctattgtc gcaggagagg agttcccagc gtcagacttt gaaactcagt attgtttggc
    23761 tacttctcgc cgtgcaaatg ctcactatgt ttattcagaa gaggatttgc ttgccaaata
    23821 tagccagcag ttcaaggtta aaaaagtcat gccagctgcc ttcgcggaac ttcaaggaga
    23881 ttacctgtat atgctgacca ctccgagtcg acaagaaatg gagcagatga ttgcagattt
    23941 cggacaacgt caagaataag aactatcgga ttaaggaaat taactccctt aatgcttttg
    24001 ttttgtctga taaaaaataa gagcatccca acaaggtagc tatcataaaa cttgttcgat
    24061 aactatttga agcaggatta ggtggttaga aattgaattt taatatttca attgagtcat
    24121 agtattgtgt tttcgtatcc ttaaatcagc taaaaggatc catgacgaca cctatacgat
    24181 atagttttca agataccaaa caagtctatt aatactcaat gaaaatcaaa gagcaaacta
    24241 ggaagctagc cgcaggtttc tcaaaacact gttttgaggt tgtggataga actgacagag
    24301 tcagtatcat atacctacgg caaggtgaag ctgacgtggt ttgaagagat tttcgaagag
    24361 tataaaatat tcaggtgacg catagatata gttaattgaa gctttgtttg aaatctgata
    24421 aaataatgat attactaagt tttaaaaact aaagaaaagg gaagatatga ttacaggcga
    24481 attaaaaaat aaaatcgatc agttgtggga aattctttgg acagaaggaa atgcaaatcc
    24541 tttaacaaat attgaacagt tgacttatct cttatttatg aaagatttgg atactgtcga
    24601 gcttggacgt gaaagtgatg ctgaatttct agggattcct tatgagggag tttttccaaa
    24661 agataaacct gaataccgtt ggtcaacttt taaaaacata ggagatgctc aggaagttta
    24721 tcgtttaatg actcaggaga tttttccgtt tattaaaaat ctcaaggggg atacagatga
    24781 tacagccttt tcacgatata tgcgagaagc tatttttcaa ataaataaac ctgctacgct
    24841 tcaaaaggca atttctatct tagatgtttt tccaactagg ggattagatg tagattttga
    24901 taatgacaaa caaagtatta ctgatatcgg agatatctat gaatatctgt tatcaaaatt
    24961 gtcgaccgca ggtaaaaatg gacagttccg tacacctcgt cacatcatcg atatgatggt
    25021 tgagttgatg caaccaacta tcaaagatat catctcagat cccgctatgg gttctgctgg
    25081 cttcttagta tccgctagcc gttacttaaa gcgtaagaaa gatgaatggg aaaccaatac
    25141 agataatatc aatcattttc ataatcagat gtttcatgga aatgatacgg atacgactat
    25201 gttgagactt ggggcgatga acatgatgct acatggagta gaaaacccac aaatcagtta
    25261 ccttgactcg ctgtctcaag ataatgaaga agccgataaa tatactttgg ttttaacaaa
    25321 tcctcctttt aagggctcac ttgactacaa ttcaacctat aatgaccttc ttgcaaccgt
    25381 aaaaaccaaa aaacagaatt actctttctt tctcttttct tgcgaacttt aaaaccaggt
    25441 ggacgagcag cagttatcgt acctgatggt gtcctttttg gttcgtctaa agctcataaa
    25501 ggaattcgtc aggaaattgt agagaaccat aagattaatg ctataatctc aatgcctagt
    25561 ggtgttttca agccttatgc tggagtttca actgccattc tcatctttac aaaaactggc
    25621 aatggtggta ccgacaaggt ctggttttac gatatgaaag cggatggttt gagtttggat
    25681 gataaatgac aaccaattag tgacaatgat attccagata ttatcgaacg ctttcatcat
    25741 cttgaaaaag aagtagaacg tcagagaacg gatcaatctt tctttgttcc agttgctgag
    25801 ataaaggaaa atgattatga tttgtctatc aataaatata aagagattga gtatgaaaaa
    25861 gttgagtatg aaccaacaga agtcatatta aagaaaatca atgatttaga aaaagaaatt
    25921 caagctggct tggctgaatt ggaaaaatta ctcaagtagg gaggtggctg tatgaaaaaa
    25981 gtgaagttgg gggaagtctt atctctaaaa aaaggcaaga aagccactgt acttgctgaa
    26041 caaacaactc taagccaacg ttatattcaa atagatgatt taagaaataa taataattta
    26101 aaattcactg aaagtttaaa tatgactgaa gcactcccag atgatattct gatagcatgg
    26161 gatggagcta atgcaggaac agttggttat ggattatcgg gagctgttgg tagtacaatt
    26221 acggtcttaa aaaagaatga gcgatacaaa gaaaaaatta tatcagatta cttgggagtc
    26281 tttttggaaa gtaaatccag ttttcttatg gaagcttatt acaaatgaga aaacaaaatt
    26341 aaaaattaag agaatttcct ctggaactag tgggagtatg aaaaatattt cgaaatcaca
    26401 attgttacaa attagagttc ccttcccccc actagccctc caaaatgagt tcgcagactt
    26461 tgtagccctg gtcgacaaat cacaattggc aatccaaaaa tctctggaag aacttgaaac
    26521 tttgaagaaa tctctgatgc aggagtattt tggctgatat tctgccattg taattacggt
    26581 aatgatttgt tataatactt caaaggagga aatcagatgg tagtaaaaac aagaaaacaa
    26641 ggaaattcaa tcaccattac gattccaagt gaatttaata ttccaagtgg tgttaaatac
    26701 gaagcgaaat tgttaccaag tggtgagatt atctttactc ctgaagaatt ggggcagcag
    26761 gtttcttatg tatctgatga tgcctttgac ttaaatttag ataaaatatt tgacgaatac
    26821 gacgatgttt tcaaagcttt ggtggaaaaa tgacaatcta tctgacagaa aagcaaattg
    26881 aaaaaataaa ttctttagca attcaacggt attctccaaa tgagaaaatt caaacagtta
    26941 gtccttctgc cttaaatatg attgtgaact taccagaaca atttgtcttt gggaagcctc
    27001 tttatccaac aatttttgat aaagcaacga tactatttgt ccaattgata aagaagcatg
    27061 tttttgctaa tgctaataaa agaactgctt tcttcgtttt ggtcaaattt ttacaattaa
    27121 acggctatcg tttttctgta acggtagaag aagcagtaaa aatgtgtgta accatcgcag
    27181 tagaagcttt aactgatgaa aaaatgacaa gctactccaa atgggtttct gaacattctg
    27241 ttagagaaaa ggtcaaaaag taacctagta tgctggattt gaatgagcac aagaaaataa
    27301 atgaacagac aatattagaa ttctgtaatg cagaaactga tattgtctct ttttattgat
    27361 gaataagaaa gtgagaaatt atggaatcaa aagttacaat tatcatgcaa gaaatgttac
    27421 ctcttttaaa taatgaacaa ttactagcgt tgagagagag tttagaacat catctagtag
    27481 acggaaaaaa gcagcagaag tattcgaata ataacctgtt gcaactattt attaccgcca
    27541 agcaggtaga gggctgtagc tcaaaaacaa ttcgttatta ccagaggacg attgaaaact
    27601 tgtttaatgc tattaaagag tctgtgacac aactcacaac agatgattta aggagttatt
    27661 tagcaaatta ccagtctgaa aaggattgta gtaaggcaaa cttagacaat attaggcgta
    27721 tattgtcttc tttttttgct tggcttgagc aagaggaata tatcattaaa aatcccattc
    27781 gacggataaa gaaaattaag actgagcaaa atgtgaagga aacttatact gatgaacatt
    27841 tggaaattat gcgtgataac tgtgaaaatt tgagagattt ggcaataata gacctactag
    27901 tatcgtgtag gggagcttgt acagttgaat cgttcagata ttgattttga aaacagagag
    27961 tgtgttgtct ttggtaaagg aaagaaggag agaccagtat attttgacgc tcggacgaaa
    28021 attcatttaa gaaattatct taacgacaga aaagatagtc accctgctct ttttgtaacg
    28081 ctagttggaa aagcccagag acttggaatt gctggtgtag agattcgctt aagaaaatta
    28141 ggagacaaac tcggcataca aaaggttcac ccacataagt tcagaagaac tttagcgact
    28201 aaggcaattg ataaaggtat gcctatcgaa caagtccaaa aactgctagg tcatagcaag
    28261 attgacacaa ccctggccta tgccatggtc aatcaaaata atgtcaagca ttcacaccaa
    28321 aaattcatct cttaaaagca aatcccgata ttccgaggag gtggttgcat gaaaaaagtg
    28381 aaattagggc aagtggctac ttttatcaat ggctatgctt ttaaacctca agattggtca
    28441 tctgaaggga aagagattat cagaatacag aatctgacta aaacttcaaa agggataaat
    28501 tattattcgg gtacgattga taaaaaatac attgttgaag ctggtgatat tcttatttcg
    28561 tggtcgggta cattaggggt ttttcagtgg tgtggaagat ccgcagtgtt aaatcagcac
    28621 atttttaaag tggtttttga taagatagat atagataaat cgtattttaa atatgttgtt
    28681 gaaaaaggtt tgcaagatgc tgtaaaacat actcatggtt ccacaatgaa acatttaact
    28741 aaaaaatatt ttgataatat tatggtttca tatacaaatt tgagagagca acaaagaatt
    28801 gcaagtgagc tggatttgtt aagcaagctg attttaagga gacaagaaca acttgaagag
    28861 cttaatctac ttgtaaaatc ccgatttaac gagatgtttg gggaaaataa aatatttgaa
    28921 agcattgata acttatttga tattatagat ggtgataggg gcaaaaatta tcctaaatca
    28981 gatgagttgt ttagtgagga
//
LOCUS       DAVDZK010000031        26027 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVDZK010000031 DAVDZK010000000
VERSION     DAVDZK010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26027
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.032"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(1..516)
                     /locus_tag="VUX16_001532"
                     /pseudo
     CDS             complement(1..516)
                     /locus_tag="VUX16_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            complement(609..746)
                     /locus_tag="VUX16_001533"
     CDS             complement(609..746)
                     /locus_tag="VUX16_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124468.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEVLNIRLEVK
                     N"
     gene            1004..1123
                     /locus_tag="VUX16_001534"
     CDS             1004..1123
                     /locus_tag="VUX16_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET8124469.1"
                     /translation="MPDIVFKIEFFHSDSLIFFYTSDDKSNLQKSQEDFSKNK"
     gene            complement(1219..2565)
                     /gene="glnA"
                     /locus_tag="VUX16_001535"
     CDS             complement(1219..2565)
                     /gene="glnA"
                     /locus_tag="VUX16_001535"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET8124470.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKAMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLHGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVRAALGEHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2602..2958)
                     /gene="glnR"
                     /locus_tag="VUX16_001536"
     CDS             complement(2602..2958)
                     /gene="glnR"
                     /locus_tag="VUX16_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET8124471.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(3035..3562)
                     /locus_tag="VUX16_001537"
     CDS             complement(3035..3562)
                     /locus_tag="VUX16_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET8124472.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDKSVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(3698..4894)
                     /locus_tag="VUX16_001538"
     CDS             complement(3698..4894)
                     /locus_tag="VUX16_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET8124473.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELET
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TVGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(4984..9859)
                     /locus_tag="VUX16_001539"
                     /pseudo
     CDS             complement(4984..9859)
                     /locus_tag="VUX16_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
     gene            10148..11778
                     /locus_tag="VUX16_001540"
                     /pseudo
     CDS             10148..11778
                     /locus_tag="VUX16_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            complement(12337..13944)
                     /locus_tag="VUX16_001541"
     CDS             complement(12337..13944)
                     /locus_tag="VUX16_001541"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET8124474.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKIFLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(14334..14921)
                     /locus_tag="VUX16_001542"
     CDS             complement(14334..14921)
                     /locus_tag="VUX16_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET8124475.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(15049..15498)
                     /locus_tag="VUX16_001543"
     CDS             complement(15049..15498)
                     /locus_tag="VUX16_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124476.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKNILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(15503..15892)
                     /locus_tag="VUX16_001544"
     CDS             complement(15503..15892)
                     /locus_tag="VUX16_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HET8124477.1"
                     /translation="MKVNIVDLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(15920..16570)
                     /locus_tag="VUX16_001545"
     CDS             complement(15920..16570)
                     /locus_tag="VUX16_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET8124478.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPETLVGFDQSIQTAIR
                     GDLPDYLTILFRSLTHLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASFCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16560..17123)
                     /locus_tag="VUX16_001546"
     CDS             complement(16560..17123)
                     /locus_tag="VUX16_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET8124479.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(17288..17506)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17560..18063)
                     /locus_tag="VUX16_001547"
     CDS             complement(17560..18063)
                     /locus_tag="VUX16_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET8124480.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFMSRMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(18256..19086)
                     /locus_tag="VUX16_001548"
     CDS             complement(18256..19086)
                     /locus_tag="VUX16_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET8124481.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVASLLLILQNQGRFYNPWK
                     "
     gene            complement(19071..20753)
                     /locus_tag="VUX16_001549"
     CDS             complement(19071..20753)
                     /locus_tag="VUX16_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124482.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLSLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETSELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(20855..21112)
                     /locus_tag="VUX16_001550"
     CDS             complement(20855..21112)
                     /locus_tag="VUX16_001550"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124483.1"
                     /translation="MKIKEKTRKQVAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(21119..21667)
                     /locus_tag="VUX16_001551"
     CDS             complement(21119..21667)
                     /locus_tag="VUX16_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET8124484.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(21682..22530)
                     /locus_tag="VUX16_001552"
     CDS             complement(21682..22530)
                     /locus_tag="VUX16_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET8124485.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQLVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            22719..24068
                     /gene="trkA"
                     /locus_tag="VUX16_001553"
     CDS             22719..24068
                     /gene="trkA"
                     /locus_tag="VUX16_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET8124486.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGGDFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            24072..25511
                     /locus_tag="VUX16_001554"
     CDS             24072..25511
                     /locus_tag="VUX16_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET8124487.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLITLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            25597..26027
                     /locus_tag="VUX16_001555"
                     /pseudo
     CDS             25597..26027
                     /locus_tag="VUX16_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         7542 a         5722 c         4788 g         7975 t
ORIGIN      
        1 tattcgttgt tgttcggata gtggggagag agcaattaat aatagattaa aattataatc
       61 attgattgca ggataacttg ttccagtaga tttattatta acacgattga taaaattatc
      121 tgataataaa taatatttca aatatgtttc gttaagtaaa gtatccaaaa caataaatgc
      181 tgtactagct atcaaatact ctttaagttc tctaactaca gcaatatttt ttagatatgg
      241 tctaactgtt gaaaataaga cactattctg cgaaactaat tttctagcac gggaaggcgc
      301 ttgttcaggt gaaagatatt gtagattttt gtagttgatt atgttctttt ttctatcaat
      361 actagacgta tctatatacc taaaggattt ctctggctta ttttgcccaa aattccaata
      421 aattgatttt atcctcaccc actcccaagt atcaggaata tcataaggaa catcaatttc
      481 ttgagtgctt ccatcagcaa acttcccata atgtttctta tgtgcttcaa gtatataaaa
      541 aggcgtaaaa atacgcctat agataatggg gttgaaatag gtttattgtt gatgagattg
      601 tagataattc aattttttac ttccaatcga atattcaaaa cctccacctt ttctgcctgt
      661 aattgttcat cataaaattc aatatcttca ggattttccc cttggcaacc tcggcagaaa
      721 tattcttccg ctcgatcagg attcaaaaat cgacaagcac aaacaaaaca gtcgccatca
      781 tcatttattg agataatata gtagattgaa ataagatgta aacaaatcga ttaggaaagt
      841 taaattagtt tctagaaatt tttagcagat gtagtgtact attctagtct caatttacta
      901 tggcttcaaa tatatctttc gaaaaaatat ttacagatgt gtaattttga agcttgcaaa
      961 agttagtaaa cttgtagatt tcgatttgaa gtaacttgtt ttcttgcccg atattgtttt
     1021 taaaattgaa tttttccata gtgactcctt gattttcttc tacacgtctg atgataaatc
     1081 taatttgcaa aagagtcaag aggatttttc gaaaaataaa tagcgaccga aatcgctatt
     1141 ttaagggtta taggtatttg atggcttaga ctgctgtgtg actgtttacc cacaggcaat
     1201 ctttcttcta tattagtatt agtaaaggtc taaataatta tcaatttccc attgtgaaac
     1261 aaaggttgca taacttgccc attcgattcg tttggcttca aggaaactag tatagatatg
     1321 ttctccaaga gccgctctga caacttcatc ttctgtcaaa gctttcaaag cgttatgaag
     1381 agttgatgga aggtctgtaa taccagcttc cttacgctct tctgctgtca tgatgtagat
     1441 attttcttcg ataggagctg gtgcttcgat tttattttca ataccatgca aaccaacctc
     1501 caacagaacc gccatagcga tgtaagggtt cgccattgga tccactgaac gcaactcaag
     1561 acgagttccc ataccacgtg aagcaggtac gcgcacaagt ggcgaacggt tacgaccagc
     1621 ccaagcaatg taaacaggcg cttcataacc tggaaccaaa cgtttgtatg agttaactgt
     1681 tgggttcatg atagcagtat agttgtaggc atgcttaatc aaaccgccaa gaaaatggta
     1741 ggctgtttct gacaactgca ttccttttgg atcatttgga tcaaagaagg cgttatttcc
     1801 ttctgcatca aacaaggaca tattacagtg catacctgat ccagcaatac caaattttgg
     1861 tttcgccata aaggttgcgt aaagcccatg tttgcgagca atggttttaa caacgagttt
     1921 aaagatttga atcttatcac aagcacggag aacttcatca tacttaaagt caatctcgtg
     1981 ttgaccaacc gcaacctcgt ggtgactggc ttctacttca aatcccattt tggtcaagac
     2041 attgacaatc tcacgacgtg tattgtccgc aaggtcagta ggcgccaaat caaagtagcc
     2101 acccttgtca ttcacttcga gcgttggatc tccattttca tccagtttaa ataggaagaa
     2161 ttctggctct ggaccaaggt tgaaagattt gaatcctact tcttccatat gacgaagagc
     2221 tcgtttcaaa ttaccacgag ggtcccctgc aaatggttca ccttctgttg tatagacatc
     2281 acagatcaaa cctgcaacac ttccattttc atctccccaa gggaagactg tccatgtatc
     2341 caagtcaggg tacaagtaca tatccgactc attgatacgt acaaaacctt caatagaaga
     2401 tccatcaaac atagccttgt tcgacaagac cttatctaat tgttcatctg tagcaggaat
     2461 ttcgacgttt ttcatggttc ccaaaatatc tgaaaacatg agacgaataa aggtaacatt
     2521 tttttccttg acttcacgac gaatatctgc agctgtgatt ggcatgagtt ttctccttaa
     2581 tgtatgacta cttgcggttg cctaaccgcg accaaaaggt gactgtactg aagcaaagcg
     2641 accctgttgg aggagttcat tgtgaagtgc acggcgcacc tcagtctgac tcaccgcttt
     2701 cttggatttc gcttcacgtt cagcatattt tttcttaatg gcagcgatat tataaccttc
     2761 agagatataa tctttgattt caagcagacg atccatgtca ttcaaggaat acatgcgacg
     2821 atttccttcg tttcgatcgg gcttgatcaa ctcttgatct tcataataac gaatctgacg
     2881 cgccgataga tcggtcaact tcataacact gccgatagga aaaacagcca tatttcggcg
     2941 aaattctttt tccttcattt acaatttcct tctttctgtc tattatagtc taaaaaaaga
     3001 caaacgtcaa ttaataatgt tataaaatgt aacattattt ttcttttttc tctaagaaga
     3061 gacgaatacg atcaatatcg taatttacga taattgcgac aaaaactccc ataaacgttt
     3121 ctgatacacg cacaaacacg tacgaaattg tctcaccact tggaattgat agggtaatga
     3181 ttaacatagc tgctacacca ccaataactc ctgctttgtt gttcatggct acatttgtca
     3241 taatggttaa catggtgcag attggaacaa ctaccaaggt cacccaaaag gcttcgtgga
     3301 aaaaggtatt taataagaag aagaccaagg catagagtcc accgatacta tttcctagaa
     3361 tacgcgaagt cccaaaatga acactcttat caaaactctc cctcaggcta aaaacggctg
     3421 tcaaagcacc aatttgaaga cctttccagc caaaaaatcc aaaaatcaag agaactagaa
     3481 aaacagcaat acctgtttta aaggttcgca taccaagttt aaactgggat ttatcgaatt
     3541 tatatttttt aaaataactc ataatctcaa ctttctattt ccattttatc ataaatcggt
     3601 gatttttatg agtaatagtt gagaggaagc gtttttattt taagcaaaag aaaagaggaa
     3661 ctttcatccc tctcttcttt gatttgttta taaaatctta tttttctgtc aaggctgcaa
     3721 gtcctggaag aaccttacct tcaagaagtt ccattgatgc tccaccaccc gtactaatcc
     3781 atgagaactt gtctgcacgg ccaaggttaa tcgctgcggc agctgagtca ccaccaccga
     3841 tgattgattt aactcctggt tgtttcacga tagcgtccat cacaccgact gtaccagctt
     3901 ggaaatctgg gttttcaaat acacccatag gtccgttcca tacaactgtt ttggcaccag
     3961 tcaaagcttc gtcaaatttg gcgatagatt ttggaccgat atcaagacca aggaagcctt
     4021 cagaaactgc ttcaccttca gtgtcacgca cttcagtgta accagcaaat gcgttagctt
     4081 cttttgagtc aactggcaag atcaatttac catttgcttt ttcaagaaga gctttcgcaa
     4141 catccaattt gtcttcttct acaagtgagt taccaatttc gataccttgt gctttgtaga
     4201 atgtataagt catcccacca ccgataagga ctttatcagc tttttcaagc aagttttcga
     4261 taacaccgat cttgtctgaa acttttgaac caccaaggat agccacgaat ggacgttctg
     4321 gagtttcaac tgcttcttgg atgtaggcaa tttcgttttc aagaaggaaa ccagcaactg
     4381 ctttttcaac gtttgctgag ataccaacgt tagatgcgtg tgcacggtga gctgtaccga
     4441 atgcatcgtt tacgaagata ccatctccaa gtgatgccca gtatttacca agttcaggat
     4501 cgtttttaga ttctttcttg ccgtcaacat cttcgtaacg agtgttttca accaagagaa
     4561 cttgtccatc ttcaagagcg ttgattgccg tttccaattc cgcaccacga gtgacacctg
     4621 ggaaaacaac atcttgacca agttttgctg ccaagtcagc tgctacagga gcaagtgatt
     4681 taccagcttt atcagcttct tctttcacac gtccaaggtg agagaaaaga attgcacgtc
     4741 caccttgttc gatgatgtac ttaatagttg gaagagctgc tgtgatacgg ttatcgttag
     4801 tgattacgcc atctttcaat ggtacgttga agtcaacacg aacgaggact tttttacctt
     4861 tcaagtcaac gtctttaaca gtaagttttg ccatgttaca aaaactcctt tatttatttt
     4921 attcgaaact attatatcat actttggaaa tataaggaaa gatttcacaa gatttttcga
     4981 tatttaatct ttatcttctc ttttccgtct caaggtcaag gctaaactag caagaccaag
     5041 gctgaccaag cctgctatta gggattcatt agcatcagct gttcctgtat ttggcaattg
     5101 tttgcttgct tcttctgatt taactgctgt attttgagct ggtttttcct gtgtagctac
     5161 tactgctggt actgttttta cttttgttcc aatttcaaca atttctggaa tcgcttcttg
     5221 gatgacttct gttgaacgaa gacgacgctg accgttttca tcaacttcaa agacatgtct
     5281 taacagtcca tctcgtccct gtatgatgac tcgttgttcc ccaactagca tctcagcatt
     5341 ttcatgctct tgacgatgaa aggcaacctt ttcctcttga acttccaatt taggagcctt
     5401 ttgttgatca gaagccggtt gataagtagg ttttggaagg actgtgtttt gtggtgctgg
     5461 tttagcaggt tgtggttttt cagcagattc ataaacaaag gcataatgag taaagtgtgg
     5521 tgctgtaaag ataacatgac tatccgtttg ttcaaaagcc aattctactg cctctttgcc
     5581 ttcaggtaag aaaaatactt tcttaacttt cttatctttt tcaattggga ttttcacaat
     5641 agaagcgtaa gagagatcaa catcttgacc tttttcatcc aaaccttcta tttcaaagac
     5701 atgagcatct tctccagcaa agtatttctt ctcttcagca cttgcttgaa cacgctctac
     5761 tttcaaatcc ttgatgacag tcttctcttt atttgagaag tgtacttcaa cacctgtttt
     5821 actatcagaa aagactgctg gcttgtcttc tttcaataaa gcaaccagat cttttagact
     5881 ctgtttcgct gttgcaagct cttctggact caaatctact ttttcaacca aggccttgtt
     5941 cttttcaaga agcggagcta gggcagaacc tgaaggatgg tttggcagcc aagagttctt
     6001 gagcctcacc tgttaagcga tcaagctctg tcttttcttc cataaatttc tcttgaccat
     6061 tcagagcttt atgagcttct gtcaatttat taagtcggtc attgacttga tcttgggtgc
     6121 tagtttcatg gtctttcaac acttgttcgg ccgcttcaat tgctttcaag aaagcttctt
     6181 ttacttctgg tgaagcaaag ttatagacca ccttgttctt agcagcttca acttctgcta
     6241 atttttgttt gaggtactca tcgttcaatg ctgcttttgg agataccaaa acatcaaagt
     6301 tgacttcatg accttggtaa cgaagcgtca aggtttgacg accagtcttt tgagcatcgt
     6361 aaccagaaat ttcaactccc tcatcagtaa aggaatgttc ttccatggtg tcattgctat
     6421 aagccactgc aaagcgtcct tcagacaagt ctaagctatc accaactagg taatcttttt
     6481 tcggttcctg acttacttca attcccaaaa tagttttcgg acttgcttca tcttggccag
     6541 tgacagtcac tgacaaatta gcatttactg gttgtcccaa atattggaga gtaagattct
     6601 gttctccctt atgatgcgta tcaaaacctg atactgatac acctgcgtga tttagacgaa
     6661 tgagttcgtc ctcagttcct ccttcatact gaactcgaag aacaccacct ctaaggtcca
     6721 aatcctcccc ttcggcgtag cttattttct taggtcctgt ttctaggctg actaacttga
     6781 ttcttctgcc atcttttgga acggaaactg ctaggacatt actaatttcc ttgcctggca
     6841 actgggtacg ataataaaga agaccagatt gatttgtcaa atccaatggt gcacttgcta
     6901 ggtctcctcc aacttcgctc ttcaaggttg cgagcggagt ttgagaattt ggattatcat
     6961 aaacggtaat agttgctcca gccggtacat ctgcaaagcc aacttgtacc ttgttattgc
     7021 ctagagaacg ggctgcagcc ttggccatcg gaatatttac actctcagta tcaagctttt
     7081 catacatttt ccagttatag atacgaatag ccttccatgg agttccattg tcagaagtga
     7141 caacattcaa gtaccagtct tgagcagtga ttggtttatc aagagtgata tctgtcacat
     7201 gtgctttgtt accacggact tccttagcta gcttccactc acaatctgca tctttataat
     7261 aaaggtcaaa gtctttggtg ttcatcaagc catcgttaac agactcacca ccagcccctg
     7321 catgatccat gacccatcta acaacggtac gtggcttggt caaacgaata tccacactac
     7381 cactcaactg agctgaagac catttatctg acaagctagt aatggtaccg ttcaacatac
     7441 cttcaatacc ttctccacct tcagtcttag ggaaagtact atcaataact gttgcacctg
     7501 gaacgatatt ttcagctagt ggttttggta ggctggtatc ttttacagtc ataccccaat
     7561 caaaggttgt ggttgcagct tctgaacgaa ctccattttt accgactgct acaaccttca
     7621 gttcttgagt tgtaccctga gcacttgctg agcggctaac ttttggtaga taaatagttg
     7681 tagaagatga gccagttagt aatttccagc tgtctccatc tttttcataa acttcataga
     7741 aatctgcatc cttgttgcct ttaaattgca caactgcttc cgcttcttgg gcatttttaa
     7801 gcgattgttt cactacagaa aagcttgttg gcgattgtgg ctcttggtga ttgtccgaga
     7861 tagttaattg tccgaggttg aactgataat cttttacagc accttcatgc tcgaaaaata
     7921 gtttgactgc atagatggtt ttacctgcta gtgagctgag atcaaattct tcatttgtcc
     7981 agttgtcaga aagggttagc tctttccatg catctgcatc atcgaatttg tagtctggag
     8041 ttgtagagaa tgccatataa actttagaac cttttcctct cttgtgggca acacgaagtt
     8101 tggtcttctc agttacttct aacttagtag aataaagtct cacatcctga tctgtcttac
     8161 cggctacatc accagagaat ttaagggaat ttccgccatt ataggcatct gtaaaatcat
     8221 attctgcacg aagtttttcc cctgttgaag tctgccacca gcgccatgtt ggaagaacac
     8281 ctgatactga acgataattc cactcagaat ccttagaaac cttaccatct acgaaccatt
     8341 ttttaccatg acctgtatta aaagaagtag taaaagtatt acctaccgct ggcgtacggt
     8401 ccgcaactag gttagcaata ccataccaat ctttgtcacc tggtttttgg ccagtagggt
     8461 ctccttgata acctgtaaag aagatatctt catttttatg ataatcttca ccagtttttc
     8521 ctaaacttgt aatggtatct ggggcaaata aaccaagaga aaggcgcaat ttcccatttt
     8581 cgtctaaaat gtcattccac ttaacctttg tcttgtagga accaccctgt tgcaattcca
     8641 aacctgcaaa tacatcataa ggattacgac caatccagtt ggcagttgca atagtgtaat
     8701 catttttagc cttatcccag ttaaagttag caaagaagtt atctgccgga accttatctc
     8761 cttctggttg catgaattgg tagttgtatt ctcccaaacc atcttgatgg taacgtccat
     8821 aattataggt catggcatca taccaagaat acttgattgg atggtttacc ttagcagcat
     8881 attccttgct atagagcata aactggcgca tcttttctcc aagaggttta accaaatctc
     8941 cagttgtttc ttggttgatg aaatagccat catagccata atacttggcc atgtctacca
     9001 atttacgggc aattgggaag ctaccatctg cgtcttgctt caaagcttca gcaaatcttt
     9061 cttgatctgc aatactatta gaccagttga agaagagtgt accgtataca ggaaccccat
     9121 tacggtgacc tgcatcaata acgtcaggag ttggtacgag accttcccag aaaaccattg
     9181 aatctagata ttgccaatag tcaaaagcat aggccttgaa ctcttctcca ccaacagaag
     9241 catggtcttt tgctttagaa ttggtgtttg ataaggcttg aacttttgct tccttgctag
     9301 ctttttcatt gactaaatga cctgtccgac gtgaagcgag gataacagat ccgcggttaa
     9361 tagcatcatc ttcacgagca cctggttccc attttaacaa ttcttcccaa gaattaaatt
     9421 tgatttcctt tggttttaat gttttttctg tatttttagg gacatctggc tggacttctt
     9481 tttcagtctt attagcttct gctgctggct tagactcatc cccttggtta gttgcttcgg
     9541 gctttgcttc tgcagatggt gtttctgcaa ccacctcacc tgctttttcc tctggtttag
     9601 ctacgctagc tgcttctgcc ttttctagct tgttttctct agcatgttcc ccttcattct
     9661 gcttatcaac ttcattggtc gaatgctcac tctctcctga aacaagctct gtattagctc
     9721 cgctattttc aggaactgca gtttcttcag ccaaggctgg accagcaaat aaaacagcac
     9781 caatcatcag cgagcaggct cctactgata acttacgaat actgtaacga caacgtcttt
     9841 caaaaaatgg attcttcatt ttctcctcct aaaagattga ttttgttgtt ttcaagaaag
     9901 cgctttatat tctgtagttt tttaactcta gaaccatgat aatcacattt ttatcctaaa
     9961 acatttttag acaaaaaaca atagctgttt tcacaaatct aaaataaggt taaaaactct
    10021 taaaaataat acacttatca attataattt tcttttacaa acttgacatt aacacttgtt
    10081 agatttactt ttatccttta aaatagaata ggagatattc cgcgattatt tttcggagga
    10141 aaaagaaatg tccattaatt ggcaggaaat tttatttcac tttttaggtg gtctggggct
    10201 attcttatat agtatcaaga ccatgggaga cggtttgcaa caagctgctg gagatcgcct
    10261 tcgtttttac attgacaaat atactagtaa tcctttcttt ggagttctgg ttggtattgg
    10321 gatgactgct ctaattcagt ctagttctgg tgtaacagtt atcacagtcg gcctggtcag
    10381 tgccggtctc ttaaccttac gtcaggctat cgggattgtc atgggtgcta atattgggac
    10441 aactgtcaca tcctttctca tcggttttaa attaggtaac tatgccctac ctatgctctt
    10501 tatcggtgcc gtctgtctct tttttacaaa aaatggacag tcaataatat cggacgtatc
    10561 ctctttggtg tcggtggtat cttttttgcc ctcaatctca tgagcggcgc aatgactcca
    10621 ctcaaggatt tacaggtctt taaggactat atgattgagc taagtaagaa tcctgttttg
    10681 ggtgtctttg tcggtaccgg cttgaccttg ctaattcaag cttcttcggc taccattggg
    10741 attttacaaa acctctacgc cggcaatcta attgacctac agggagcttt gccagttcta
    10801 tttggtgaca atatcgggac aaccattaca gccatcattg cctctttagg ggctaatatt
    10861 gcagctaaac gggtagcagg agctcatgtt gccttcaacg ttatcggaac agtcgtctgc
    10921 gttatttttc tagttccttt tactgtcctg attcattggt ttgaagctac gctaaatcta
    10981 gcaccggaaa tgaccatcgc ctttgctcac ggaaccttta atattaccaa caccattgtc
    11041 caatttccat ttatcggagc tctggcttac tttgtaacca agattattcc tggagaggac
    11101 gaggttgtca aatacgaacc cttatatctt gatgaacatt tcatcaaaca ggccccatct
    11161 atcgctctag gaaatgctaa gaaagagctc ttgcacttag gaaactacgc tgctaaagcc
    11221 tttgaccttt cctataagta catcattgac ttggatgaaa aagttgctga aaaagggcat
    11281 aaaaccgaag aagcaattaa caccatcgat gagcaattaa cacgttatct cattgccctt
    11341 tcaagcgaag ctctcagcca aaaagaaagt gaagtgctta ccaatatcct tgattcctcc
    11401 cgtgatttgg aacggattgg agaccacacg gaggctctac tcaatctgac tgcctatctt
    11461 caacggaaaa atgttgaatt ttctgatgcc gccttgaaag aattagagga agtttaccgc
    11521 caaactagtg actttatcaa agatgctctg gatagtgtgg aaaacaatga tattgaaaaa
    11581 gcacgcagtc ttgtagaacg tcatgaaaca atcaataaga tagaacgtgt tctcagaaaa
    11641 acccacatca aacgcctcaa caaaggcgaa tgttcaacac aagctggggt caactttatc
    11701 gacatcatct cacactacac tcgtgtatca gaccacgcta tgaaccttgc tgaaaaggtt
    11761 tttgcagaac aaatctaaga accaagaagc tatccatcat aattggatgg ctttttactt
    11821 ttttctaagc aagactaggc tgaatgaaac tgaaagagta ttctacagat atatagtata
    11881 ttgaaactag aatagtacac ctctatttct aaaacattct tagaaatcga tttgactgtc
    11941 ctgaacgatt tgtcctgtta ttatttcatt ttattatagt ggattaaatt aaaaaagtat
    12001 agtatattga atctataaca gtacatcttg actgctaaaa tatttctata aattaatttg
    12061 actttcctga tagagatgtt cacatcttat ttcaattcac tatacaatcc agttcctaaa
    12121 actttgctag aaattgattt ggctttccga attaatttgt tcaaatttta tttcatttca
    12181 atatactgat aaatccattc actagcacag ggcaagaggg agtcgctatt gatttcaagg
    12241 gtagcaggta catacagagg actcctacct cagatatact gcaatatcat cgtatgcaaa
    12301 aaacctctga gatttttctc aaaggttctg attttgctaa ttgctgttct caaccgctgc
    12361 agtaacaaag gcagtgtaga gttcttctgg tcggtttgga cggcttgaca gttcagggtg
    12421 atactgacaa gctacaaaga atttattttc aggaatttcc acgatttcta ccaaacgatt
    12481 gtctggagaa actcctgaaa agacaaaacc tgctgcctca aactgctcac ggaaggcatt
    12541 attaaactca taacggtgac ggtgacggcg ttgcaccact tcttgattgt gataagcagc
    12601 agcagcctta gagccacgtt tcaacttaga cggataaagt cccaaacgaa gggttccacc
    12661 catatcctca atatcaatct gatcacgcat gatatcaatg atagggtatt ttgtttctgg
    12721 tgcaagctct gcagaattgg caccttcaag acctaaaacg tgacgagcaa actcgataca
    12781 tgtcaactgc attcccaagc agactcccaa cattggaaca tcattttcac gcgcatagcg
    12841 gatggcttgg attttccctt ctgtaccacg ttgaccaaaa ccacctggta cgatgatccc
    12901 gtccgcatca gacaagagtt ctgctacatt ctctgctgtc acatcattgg cattgaccca
    12961 attgatttta acttctacat cattgacata gccagagtgt ttcaaggctt cgaccactga
    13021 gatataggca tcttgcaact ccacatactt accaacaagg aaaatcttaa cttgtttctt
    13081 gaggttcatg accttgtcca ccatggctga ccattctgtc atatccgctg ctggtgcgtc
    13141 taatttcaaa tgatcacaaa caatttggtc catcccttgt gcctgcaagt tcagtggaat
    13201 ttggtaaagg tgttcaacat ccaacgattc gataacggct tctggtgcca catcacagaa
    13261 ctgggccagt ttatttttaa ttccttgacc agctggctct tctgtacgaa taaccaacat
    13321 atttggttgg attcccaagc cacgcaattc tttgacagag tgttgggttg gtttggtttt
    13381 catttcacca gcagccttga ggtaaggaag caaggttgta tggatataca tgacattatc
    13441 cgcacccaca tctgccttca tctgacgaag agcctctagg aatggcaagg actcgatatc
    13501 tcctactgtt ccaccaacct ctgtgataat gacatcagag tcggtcgtta gagcggcacg
    13561 cttgattttt tctttcaaag catctgtgat atgaggaatg acttgaacag ttgccccaag
    13621 gtattctcca cggcgttctt tacgaagaac ttcactgtaa attttcccag ttgtcacgtt
    13681 ggaatatttg ttgagattga tatcgatgaa acgttcatag tgacccaagt ccaaatctgt
    13741 ctcagctccg tcatctgtca caaaaacttc cccgtgctgg taaggactca tggttcccgg
    13801 atcaatattg atataagggt caaacttttg aatggttact ttgagaccac gatttttcaa
    13861 gagacggcct agactcgctg ccacaatccc tttcccaata gacgatacca caccaccagt
    13921 tacaaaaata tatttcgtag acatagattc ctctttctaa aatgctcaag gtcttgttaa
    13981 ctacgagggg atatagaaaa caagacccta ctaataagaa taatctggga cgactgcacc
    14041 agattcacaa ctaatactct tcgaaaatct cttcaaaccg cgtcaacgtc gccttgccgt
    14101 agatatgtgt tcctgacttt gtcagtctta tctacaacct caaaacagtg ttttgagcag
    14161 cctacggcta gtttcctagc ttgctctttg attttcattg agtataaaat acaagaagat
    14221 aacttcttga aaaaacaaaa atagctccct aagaactagg gagccccgac ctctaaaaga
    14281 ggtgcccaaa caatatgata cctaaaaata ggataattgt caatagctaa ctcttattcc
    14341 tcgctggttt cagcgtcgtc atctgaaaac tcgtcgtcgt cttcgttgag atccacatct
    14401 tctcccaagt catctggagc gatttcgttg atttctgcat cataagcttc cacttcattt
    14461 ttttcatcat ctggattttc atcatcgtat gaaagagctg gatctgcttc gtatgcatct
    14521 tcgtcttctg gatcatctgc attgtagtca atggcatctg aatcaccatc cataaaggca
    14581 ttgacacgtt ttttcttagc ttttggtgct acttcatcgt cgtcattttc ttcaagagcg
    14641 atgatttctt cgtcgatttc gtccacacca taccatgaac gaagacccca tttgttgtcc
    14701 ccaagtgaga tgaagctacc gtcaaagttc aactctgtgt agaacaaagg caaagcttcg
    14761 cggatatcgc tgtttgatgt tccaaggtag ttttgaattt cgtttacaag atcgctaaaa
    14821 tgcatctcat gatcgcgacc acgaagttcc aagatagcac gcgctacctc aatcatagat
    14881 agttcacttt tttcttgccc agcaaatact tctaattcca aagcgtttct cctcatttat
    14941 actactatcg ccagagcgaa cagactctga cctcatttta tcatttactc tttattttac
    15001 gataattttg cggaatagtc aaaggttaag ggggagaaag tggcaggatt agactaattc
    15061 caatataaaa ctccttcctt tttctgttgc tccattttcc acaaatccaa gcgacttgaa
    15121 acacctccta gaagcatgat tgtaggtgta gatttccttg actctcaatt ctttccatcc
    15181 ttttactcga gccaattcaa tcaaagcact tagaatattt tttccaagtc ctcgatgttg
    15241 gtaagcggaa ttcccaatca caatggggag attatcctga gatagtgtaa tatccccaat
    15301 tggaaaccat tctcccttct ccttgacttc aatccaaaaa agctcaccat gccgatccaa
    15361 ataggaatac atggcttcca aggtcgcttg actgtaagga agcttcaccc catctacgag
    15421 gtaaaccaag ttcacatcct gataccaagc aaaagcttcc tcacaataat tgaccttata
    15481 ataaggaaca aaacacaatg cactaccttt tcaacaaaag agttgctgct tgattaaaac
    15541 catcacacca gttataccat tttgcttcat acccatcttg agctaggata cgatcttcta
    15601 aatcaaaaac agagtaaatc tttctttcct cgcaagcttg cgcatagaga tgatatagtt
    15661 catcaccacc atctctatcc cactcagcag aaatcgtatc ccgacctgcc aataaagcct
    15721 gataagccct gtgatgccca tctgtaatca gcaaacaatc tccaaaggca agaatactga
    15781 ttggatcgac ttggtttgtt tctgccgact ggtaaagcat ctgaatatct tgcaacttct
    15841 tttctgataa atatagttga gtcggatgaa gatctactat attgactttc atttctttct
    15901 cctcaaggga attcgatact cacttctgtt tgcctttaaa tcgccattgg aagcggagct
    15961 tgtcatagaa gggaaactcg ataaacaaga ctcccaaacc cacacagaaa ctggcaagaa
    16021 catctgatgg gtagtgaact cccagataga ctcttgatac cagcacactg actaggtaga
    16081 ggccaaggac gatttgtacg atttttctcc agacctgatc tttaatccgc tgactaagaa
    16141 taacaatcaa agtccctacc atcagcgtta cagctagaga atgcccactt gggaaggaaa
    16201 atcccttctc ctccaccaga tgtaagatag ctggtcgtgg gcgctggtag atatttttaa
    16261 aggtcacgat taaaagacct gccaaagcca gatttcccag catgaagaaa ctttctatct
    16321 tccatcgctt acgataaaag acaaaagcta taatgacaac ccaagtgata atcactggaa
    16381 tatcaatcag atgtgtgagg gatcgaaaaa gaatagtcaa ataatctggt aagtctcctc
    16441 gaatggcagt ctgaatcgat tggtcaaaac cgaccagcgt ttcagggtaa aatttgacca
    16501 tgtagccaag aataacgaaa agtaaaaggg caaaactgcc cttcattaaa aatgtttgtt
    16561 tatctttcat agtgttttaa ggttggtttc aaaaggacgt acaacaacca gaatgaaacg
    16621 gaaaagatta caccctcaat caagttaaaa ggtaatacca tggtcattag gtagttggaa
    16681 agtcccaaaa tttttccaat atcaaagtta gcaaacttag cgtacaaagg aacagcataa
    16741 acatagttga gaaccaacat ggccaaggtt aaaccaacag ttccagctag agagcctagt
    16801 aggaaacgaa gggttgtccg ttcctttttc caaatcaaag caaatacgat gacaaaaact
    16861 cccaaagcta cgatattcat cggcaaacca atgtaagtat tcactccttg gctgttaaga
    16921 agcaatttca atagtgagcg aagcaagagc actcctagag cagcaggcaa atccatgacc
    16981 accagaccca caaggactgg caagatacta aattcgatct tgaggaaaga tgccgctggt
    17041 aaaagcggaa agtcaaagta catcagcaca aatgagatgg ctgatagaat tgcaatggtc
    17101 gaaagtcgac gtgtgtttgt cataacaggt tcctccaatt ttctataaaa tcagaagaag
    17161 ttggaaagga ttcctctatc tattctcact ttttatatcc caaaagttcc ctcttactct
    17221 attaaagaaa aacaaagcaa gtggttacaa tccggctata aatctatcaa aacagacaaa
    17281 gctattcttt cgtcttctcc catccagact atactgtcgg ttgtggaatc tcaccacatc
    17341 agcttgcgct cgcggactta ttttgctaag atattttaga tttatctagg cgtcgcagtc
    17401 gaagataata cttaaggtat atcgagacaa aacaacgacg agaaagctaa aatagctagt
    17461 caaatttacc gccggtcggg aatttcaccc tgccctgaag actcttttat cataacaaaa
    17521 aacgcttgca agcgcaagca ttttgttcat tttcattttt tatttcaatt tatccacttc
    17581 ataggtatgg acgagctcaa gacctgcaaa gttctgctgg cgaagagcct catagacaat
    17641 catgcagacg gtattagaca cattgagact gcggacatgt tcatcattca tgggaatacg
    17701 aagagccttc tcaggatgtt ctcgcataaa atcttcaggt aagcccttgt cttcacgtcc
    17761 aaagagaaaa taatggtcct cgtcagtcga taaatccacc tcagaataga ctttttccgc
    17821 gaatttcgaa atcagataga gttttccctt catccgagac atgaaatctt ccaaactctc
    17881 gtaaaaataa atctctagct tatcccagta atccaatcca gcccgcttca tcttgcggtc
    17941 atcaatagga aagcccatag gcttgatgat gtggagggga gaattggtcg cagcgcaagt
    18001 acgcgcgata ttgcccgtat tttgtggaat ttgaggttca aataatacaa tgtgatttgt
    18061 catgacttgc ttcctttcac cattgcaaaa aaatagccac actgcccgga gtcaagctca
    18121 gcaaacagcg tggttaaggc atcgttaact tacctcacaa caggtttgaa gtaaatcagc
    18181 gaaactactt tcttagtata acactttcag aatcattgtc aatagaaacg acttgatttt
    18241 ttaaattttt tcaagctatt tccaagggtt gtaaaatcgt ccctgattct gcaagataag
    18301 tagtaaacta gctactaaaa acaaggttgc caagagcaag gtaatatagt ctcctttttt
    18361 caaggcctga taactatacc atgtgcgttt tttctctttc ccaaagcggc gaagctccat
    18421 ggcagtcgca atggtatcaa tgcgttctag cgagctaaaa atcaagggcg taataatgag
    18481 cagattgcct ttgattcgtt gcataagaga agctttcttg gataattcca tcccacgcgc
    18541 ctcctgagac atcttgatag taaagaattc ttcctgcaaa tctggaatat agcgcaaggt
    18601 caggctgaca gaataagcaa tcttataggg cacaccaatt tgatttaaac tggaagcaaa
    18661 ctgactagga tgggttgtca tcaaaaagat aatagccaga ggaatggtgc aaagatactt
    18721 aatggccaaa tttagcagat aaaagagctc ctggctggtt agagtgtaga caccgattcc
    18781 ctgccaaatc acacttctct ctccataaag tccaacccca tactcgggag aaaagagata
    18841 gaccatcaaa acgtttaaaa cggcaaatac cgtcgcaaaa acggctacaa aggagacatc
    18901 tttaaagcgg atttctgata aatagaggag aaagactgaa aagatggcaa tcagcaagag
    18961 cattctggta tcatagctaa tcatggccgc caatgatacc agaatgaaaa agagaagttt
    19021 cccagctcct gacaagcgat gaatcacagt atctctatgc tggtaaccga ttaatttagc
    19081 ttgcatccct ctctcctttc tttgtaaaat gccgttaaat ccagtggatc cacatctagt
    19141 ttcttagcca agttaaagat ggaggtttct tttagattgg cttttactaa cagctcagga
    19201 tcgctcaaca gactggctgg aacagtatcg gcaatcaatt ctccatccac catgacaagg
    19261 acccggtctg aataatccag catcaattgc atatcatggg taatcatgac aatggtatgc
    19321 cctttttgat gtaactcttc gagaaattcc ataatctcag tatagttctt ctgatcttga
    19381 cctgcagtcg gttcatctag gagaataatt tcagctccta agaccaaaat tgaagcaatg
    19441 gtgacacgtt ttttctgacc aaatgacagg gcagaaatag gccaattacg gaattcataa
    19501 agtccacaga ttttcaaggt ttcatagact ctcgtttcaa tttccttctc atccacacct
    19561 cgcaaacgga gccctagagc cacctcatca aaaatcatat tggttgaaat catttgatta
    19621 ggattttgta gcacatatcc tactcgttcc gcccgctctg caacagaatc gccttttata
    19681 tcctgttttt cccaaagata gcgtccttcc gtctgaataa agctacttat agccttggct
    19741 agagttgatt tccctgctcc attttttccg acaatagcaa tcttttcacc ctttttaata
    19801 tctaaatgta gggattttaa aatcggtcta tcatcataag aaaaagatac ttcctctagt
    19861 ctaaagagtg actgcaattc tgaggtttct tttaccagtt ccgtctgtaa ctggacttgc
    19921 ccttttgaga tagacaagtt atccagatct gctaattgtt cttccttgac taagtccaca
    19981 cctaattgac ggagagtggt tagataaagg ggttctcgaa ttccattttg agtcaataaa
    20041 tcagtcgcaa gcaactggtc agggctccca ttaaaaagga tacgaccatc gtttatcaag
    20101 acaatccgat ccacagggcg atgcagaacg tcctccaaac ggtgctcgat aatcagagtc
    20161 gtcgtcccct cttccttatg aatctggtca atcaattcga taatatcctg acctgacttg
    20221 ggatctagat tggcgagtgg ctcatcaaac aagagaatcg gactttcatc aatcaagaca
    20281 ccagccagac tgactcgctg cttttgtcca cctgacaaat cctgaggacg ctgatccagt
    20341 aaagaaagaa ggtccaactt ttcagcccat ttataaacac gacctttcat ctcatctagg
    20401 gctgtcacat cattttccag agcaaacgcc aaatcttctg ccacagacaa gccaataaac
    20461 tgcccatctg tatcctgcaa aactgtgcta accagatgag acttatcata gatgctcata
    20521 tcaaaggcta cttgaccctt tatcaaaaat tctccatatg tctgaccctt gtaaatattg
    20581 ggaataatcc cattcaaaca ctgacccaag gtagatttac ctgacccaga tggtccaaca
    20641 attaagactt tctctccctt gtaaatggtc aagtctatcc cttgcaaggt cggttcttgt
    20701 tgtgtttcat accggaaaga gaaatccttc cactcaatta tagcttcttt catcttactc
    20761 tcttcattcg cttcttagac ttctatttta tcataaatca agcccttctt gcagtctctc
    20821 ctcttaaaat cttagcgcca aaaagattcc tatcctagct tacttgccta actaatctat
    20881 aaacatcgaa aaagactagt tgcccagcct tccccatcat tttatactct tcgaaaatct
    20941 cttcaaacca cgtcagcttc gccttgccgt aggtatggtt actgacttcg tcagtttcat
    21001 ctacaacctc aaaaccatgt tttgagctga cttcgtcagt tctatccaca atttcaaaac
    21061 actgttttga gcaacctgcg acttgcttcc tagttttctc tttgattttc attgagtatt
    21121 agtccttttt caaacttcct gcacgagttt gggttcctgc ataggcaagt aagagaagag
    21181 ttcctgcaat agctacagat acaccattgg caattcccgc aacaatccct tgtgcaaata
    21241 ctttttctgc cgcttcttga taaatcacaa catctccaag tggtgccaag acaccccaaa
    21301 caagggcatt tgcaagtagt tgaatgagat taaaaataag aatatctttc cagtcaaaaa
    21361 cactattgat cacgcgaacg tactttctaa aaagtcccac aactaaacca aagagtccgc
    21421 tagcgataat ccaagtccac catagaccat aaccaacaag agagtccttg attgcatgac
    21481 caatcaaccc gacaagcaaa ccgataatcg gtccaaaaat aatagaaagt agcgcttgta
    21541 ccgcatactg aagctggatg cttgtatttg gaacaggggt tggaatgttg atcatcccga
    21601 tgacgacaaa gagggcagcg ccaattccga cagcaacaac ttgtttaatt gtaaatttga
    21661 tttccatact attctcctat tttatccttc tattttcttt atttcaatgg tccaagatga
    21721 accgacacct acattatagg ccttggcaaa ggaaccttgg ttgatagcca aacctaaacg
    21781 atagagagag ttgatgtaaa ggatgggttg cccaattctc acatctgcaa atgatttgcc
    21841 atagacaagc tgattttgat agaccagcat atcagcatga tagatggtca cttcaaaacg
    21901 atcaccaaat tctggttcca gcttgtaaaa ttcttcccgt gtgatagagg tccaaagcga
    21961 accgaaacgc acatccagaa tatcaatggc tcccttcacc agatgatctt ctatgatggt
    22021 cgctacgact ggaagctcta caatctgttc cacactgagc tctggcccta cttcctcaaa
    22081 agtaatgtga ccactggcca gtttagcacc agtataggca tagacatcac gaccgtggaa
    22141 ggtataagaa tgctctgtgt tttgacgcct attggccacc tcagaaatct cacgaatggc
    22201 tacaatgcca acgtgtttct tgataaagga aagcgtccca ttatctggcg tgacaatgta
    22261 ttgatttttt gcagtcttgg caactacact cttacgtttc gaaccgacac ctggatcgac
    22321 aaccgataca aacgtcgttc cctcaggcca gtaatccacc gtctgaaaga gacgatagct
    22381 cccctcaaaa atattataag gcgtgatatc gtgcgtcaag tgatggattt ttaaggttgg
    22441 agactcttct aaagccactc caatcatagc cgataccgca ccatcaacca gaccaaagtc
    22501 tgattgtaat accagtaaat tattattcat tttatctcct tgtatatcct ttatcatacc
    22561 atatttcaga gaaagtcgct aatagctatt tcaattggtt agggtatagt tttaccttat
    22621 agcaaatttc ctactaaaag ttcttgttat tagctagtag gtgcattttt tcttgaaaaa
    22681 gggtatgata gttacatcat gaaaaagtag gttttattat gaaaattatc cttgtcggag
    22741 ggggaaaagt tggttttgct ctctgtcgct ccttggttgc agaaaagcat gatgttttgc
    22801 tgattgagca agacgaagct gttctcaatc atattgtcag tcgctttgat atcattggta
    22861 tccttggtaa cgggggcgat tttgccattc ttgagcaagc cagcgtccaa gattgtgata
    22921 tctttatcgc cctgactgag cacgatgaag tcaacatgat tgcagcagtt ctagccaaga
    22981 aaatgggagc taaagaaact atcgttcggg tgcggaaccc tgaatattct aactcttatt
    23041 tcaaggaaaa gaatattctc ggtttttctc ttatcgttaa tcctgagctc ttggctgccc
    23101 gcgctatcgc gaatatcatt gacttcccca acgccctgtc tgtcgaacgc tttgctggtg
    23161 gacgcgttag cctcatggaa tttgtcgtca agtccaccag cggtctttgc caaatgccca
    23221 tttctgattt tcgtaaaaaa tttggtaatg tcattgtctg tgcgatagag agggatcatc
    23281 aaattatcat tccaagcggt gacatgactg tacaggataa agatagaatc tttgtcactg
    23341 gtaaccgtgt cgatatgata ctcttccata attattttaa atcacgcgcc gtgaagagcc
    23401 ttctcatcgt tggggcaggt agaattgcct attatctact tggtattctc aaagatagtc
    23461 gtatcgatac aaaagtcatt gaaatcaatc ctgaaatcgc cagcttcttt agcgagaaat
    23521 tcccaaatct ctacatcgtt caaggagatg gaaccgcaaa agatatcctg ctggaagaaa
    23581 gtgctcaaca ctatgatgcc gttgcgactc taacaggagt cgatgaggaa aatctgatta
    23641 catctatgtt ccttgacagg gtaggtgtac agaaaaatat tactaaggtc aatcgtacca
    23701 gtctcctcga gattatcaat gcgcctgatt tttcaagtat catcacacct aaaagcatcg
    23761 ctgtagatac gattatgcac tttattcgtg gtcgagttaa tgcccagtat tcagaccttc
    23821 aagccatgca ccatctagcc aatggccaaa ttgaaaccct gcaattccat atcaaggaag
    23881 ccaataaaat gactgccaaa cctctttctc aactgaaatt gaaaaaaggg gttcttattg
    23941 cagccattat tcgaaagggc aagactattt tcccaactgg ggaggatatg ttggaagttg
    24001 gagacaagct cctagtaaca accttgttgc caaacatcac caagatttat gacttgattg
    24061 cgaggtaaga aatgaataaa agtatgattc gttacctcct ttcaaagtta cttttgattg
    24121 aagctgttct cctcttggtt cctgtggcta tcgctgtcta ttaccgtgaa tcgagccaag
    24181 tctttacagc cctcttttcg accataggga ttctcgtatt gttaggcggt tcagggagtt
    24241 tacagaagcc aaaaaatcaa cggatttatg ccaaggaggg agtcttgatc gttgccctct
    24301 gttggatcct ttggtctttc tttggtggtc tcccctttgt cttttctggg caaatcccta
    24361 gcgttattga tgcctttttt gaaattagtt ctgggtttac aactactgga gcaagtattt
    24421 tgaacgacat ttcggttctc agccgttccc tcctcttctg gcgaagtttt acccacttga
    24481 ttggagggat gggagtgctt gtttttgcac ttgctattat ggacaatgcc aaaaatagtc
    24541 acctagaagt aatgaaggct gaggttcctg gtcctgtctt tggtaaggtt gtatccaaat
    24601 taaaaaacac tgcccagatc ctctatctcc tttacatagc cctcttttcc ctctttgtca
    24661 tcatctatta tctagccggt atgcctctct acgatagttt tgtcattgct atggggacag
    24721 cgggaactgg aggatttacc gtctataacg atggaattgc ccactatggt agctcactga
    24781 ttacctatct ggttagtata ggagttttgg tttttggggt aaatttcaat ctctactact
    24841 accttatgct ccgtcgggtt aaggccttct ttggagatga agagcttcgg gcttacttgg
    24901 tcatcgtgct ggtttctaca ggcttgatta ccctcaatac tctctacctc tacccaggat
    24961 tttccaaaag ctttgaaatg gccttcttcc aggtttccaa catcattaca acaactggtt
    25021 ttggatatgg agatattacc aactggcccc tcttctccca gtttatcctc ctcttcctca
    25081 tgacaatcgg tggttctgct ggatcaactg caggtggact caagattatt cgaggcctca
    25141 tcctttcaaa aattgccaaa aatcaaattt tgtccattct atctccccac cgtgttttga
    25201 ctctccatgt gaataaaacg gtgattgata aggataccca gcataaaatt ctcaagtact
    25261 ttgtcatcta tgctatgatt ttgctatccc ttatctttat tgtcagccta gatagcaatg
    25321 attttctgat cgtgaccagc gctgtcttta gctgtttcaa taatatcggg cctattctag
    25381 gaaccacttc tagtttctca atctttagtc ctatctcaaa aattctcctc tcctttgcaa
    25441 tgattgcagg ccgcttggag atttacccaa tcctacttct ctttatgaag agaacttggt
    25501 ctaagagata aaatacaaaa tctctctttt tacaattatg aaagagggat tcttatatta
    25561 tacttcctgc ggaacaaaat atggtatagt agttctatga attatgaagc aagtaaacaa
    25621 ctaactgatg cacgattcaa gcgtcttgtt ggtgttcagc gcatgacttt taaagagatg
    25681 ttagctgtat taaaacagct tatcaactta aacacgcaaa aggtggacga aaacctaaat
    25741 taagcctaga agaccttctt atggtcactc ttcaatatgt gcgagagtat cgaacttatg
    25801 aagaaattgc ggctgatttt ggtatccacg aaagcaactt aatccgtcgg agccaatggg
    25861 ttgaagtaac tcttgttcaa agtggtgtta cgatttcaag aactcctctc agttctgagg
    25921 acacggtaat gattgatgcg acggaagtac aaatcaatcg ccctaaaaaa agaattagcg
    25981 aatgattctg gtaaaaagaa atttcacgct atgaaggctc aagcgat
//
LOCUS       DAVDZK010000032        25408 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVDZK010000032 DAVDZK010000000
VERSION     DAVDZK010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25408
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.033"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            38..1756
                     /locus_tag="VUX16_001556"
     CDS             38..1756
                     /locus_tag="VUX16_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET8124488.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLTRRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            1867..2214
                     /locus_tag="VUX16_001557"
     CDS             1867..2214
                     /locus_tag="VUX16_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET8124489.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFVGL"
     gene            complement(2492..3328)
                     /locus_tag="VUX16_001558"
     CDS             complement(2492..3328)
                     /locus_tag="VUX16_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET8124490.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYVDF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(3341..3970)
                     /locus_tag="VUX16_001559"
     CDS             complement(3341..3970)
                     /locus_tag="VUX16_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET8124491.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(3980..4621)
                     /locus_tag="VUX16_001560"
     CDS             complement(3980..4621)
                     /locus_tag="VUX16_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET8124492.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(4767..5996)
                     /locus_tag="VUX16_001561"
     CDS             complement(4767..5996)
                     /locus_tag="VUX16_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET8124493.1"
                     /translation="MNNSQQMLQALEEQDLTKAEYYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLMLGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(5986..7152)
                     /locus_tag="VUX16_001562"
     CDS             complement(5986..7152)
                     /locus_tag="VUX16_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET8124494.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAISIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VWASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFMPTKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFMIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVISGLYELEGEEVKSEQ"
     gene            7296..8309
                     /locus_tag="VUX16_001563"
     CDS             7296..8309
                     /locus_tag="VUX16_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET8124495.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKTGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIRLSTDGQYLYASNRGHNSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIAVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(8355..8774)
                     /locus_tag="VUX16_001564"
     CDS             complement(8355..8774)
                     /locus_tag="VUX16_001564"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET8124496.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDEDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(8785..10191)
                     /gene="atpD"
                     /locus_tag="VUX16_001565"
     CDS             complement(8785..10191)
                     /gene="atpD"
                     /locus_tag="VUX16_001565"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET8124497.1"
                     /translation="MSSGKIAQVMGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKILVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(10277..11155)
                     /locus_tag="VUX16_001566"
     CDS             complement(10277..11155)
                     /locus_tag="VUX16_001566"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET8124498.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLSDQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(11171..12676)
                     /locus_tag="VUX16_001567"
     CDS             complement(11171..12676)
                     /locus_tag="VUX16_001567"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET8124499.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENAMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(12691..13227)
                     /locus_tag="VUX16_001568"
     CDS             complement(12691..13227)
                     /locus_tag="VUX16_001568"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET8124500.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAYPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(13227..13721)
                     /gene="atpF"
                     /locus_tag="VUX16_001569"
     CDS             complement(13227..13721)
                     /gene="atpF"
                     /locus_tag="VUX16_001569"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET8124501.1"
                     /translation="MHVTVGELIGNFVLITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(13735..14451)
                     /gene="atpB"
                     /locus_tag="VUX16_001570"
     CDS             complement(13735..14451)
                     /gene="atpB"
                     /locus_tag="VUX16_001570"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET8124502.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(14486..14686)
                     /locus_tag="VUX16_001571"
     CDS             complement(14486..14686)
                     /locus_tag="VUX16_001571"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET8124503.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(14761..15768)
                     /locus_tag="VUX16_001572"
     CDS             complement(14761..15768)
                     /locus_tag="VUX16_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET8124504.1"
                     /translation="MQNYYTTKGKHLTIDSRCLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGCFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHRGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIAQRPEAINLRLENGHYEIDTVLLTRSKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHPYASWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            complement(16225..16587)
                     /locus_tag="VUX16_001573"
     CDS             complement(16225..16587)
                     /locus_tag="VUX16_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124505.1"
                     /translation="MENKESHKSQEIGNLLRVYNRSKREETESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYL"
     gene            complement(16976..17458)
                     /gene="greA"
                     /locus_tag="VUX16_001574"
     CDS             complement(16976..17458)
                     /gene="greA"
                     /locus_tag="VUX16_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET8124506.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVIIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVDSYDVKILKVEKTA
                     "
     gene            complement(17529..19184)
                     /gene="mltG"
                     /locus_tag="VUX16_001575"
     CDS             complement(17529..19184)
                     /gene="mltG"
                     /locus_tag="VUX16_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET8124507.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPRPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVTSFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRNR
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(19265..19759)
                     /locus_tag="VUX16_001576"
     CDS             complement(19265..19759)
                     /locus_tag="VUX16_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124508.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(19756..20220)
                     /locus_tag="VUX16_001577"
     CDS             complement(19756..20220)
                     /locus_tag="VUX16_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124509.1"
                     /translation="MEIPIKIIQASKSDLPEIEALQTSSFPAEKQQPSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEDATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(20230..21564)
                     /locus_tag="VUX16_001578"
     CDS             complement(20230..21564)
                     /locus_tag="VUX16_001578"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET8124510.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADKNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLKDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFESEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFVHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(21576..22193)
                     /locus_tag="VUX16_001579"
     CDS             complement(21576..22193)
                     /locus_tag="VUX16_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET8124511.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(22241..25339)
                     /locus_tag="VUX16_001580"
     CDS             complement(22241..25339)
                     /locus_tag="VUX16_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET8124512.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSGCAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPTLFMEDYQ
                     GVSGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
BASE COUNT         7461 a         5637 c         4697 g         7613 t
ORIGIN      
        1 aactgattaa atgttttaaa aataaaggag aatttgaatg tcttaccaag aaaattacca
       61 gaaatgggtt gattttgtgg agcttcctga ctaccttcgt caagatttgg aaaatatgga
      121 cgaaaaaact aaggaagatg ccttctatac aaatcttgaa tttggtactg caggtatgcg
      181 tggcttggtt ggtgctggta caaaccgtat caacatctac gttgttcgcc aagctactga
      241 aggattggct cgtttgattg agtcaaaagg tggaaacgag aaagaacgcg gtgtcgcaat
      301 tgcctacgat agccgtcact tctcacctga gtttgccttt gaatctgcgg cagttcttgc
      361 taaacacggc atcaaatctt acgtatttga aagccttcgt ccgactccag aactatcatt
      421 tgcagttcgt catctcaact gtttcgcagg tatcatggtc acagccagcc acaaccctgc
      481 tccatttaac ggttacaagg tttacggtga agacggtgga caaatgcctc cacacgatgc
      541 ggacgctttg actacttata tccgtgcaat cgaaaaccca tttgcagttg aagttgctga
      601 tgtggaaact gaaaaagctt ctggcttgat tgaagttatc ggcgaagctg ttgacataga
      661 ataccttaaa gaggttaagg acataaacat caacccagcc ttgattgaag aatttggtaa
      721 agacatgaag attgtctaca caccacttca tggtactggt gaaatgttga ctcgtcgtgc
      781 tcttgcccaa gcaggatttg actctgttca agttgttgaa gcgcaagcaa ctgctgaccc
      841 agacttctca actgtaacat ctccaaaccc agaaagccaa gcagcctttg cccttgctga
      901 agaacttggt cgtcaagttg gtgcagatgt tcttgtcgca actgacccag acgctgaccg
      961 tgttggtgtt gaagttcttc aaaaagatgg tagctacctc aacctttcag gtaaccaaat
     1021 cggtgctatc atggctaaat acatcttgga agctcacaaa aacgctggaa ctcttcctga
     1081 aaatgccgct ctctgcaaat ctatcgtttc aactgacttg gtaacgaaga ttgctgaaag
     1141 ctacggcgca actatgttca acgtcttgac aggtttcaaa tttatcgctg aaaaaatcca
     1201 agaattcgaa gaaaaacaca accacactta catgatggga tttgaagaaa gcttcggtta
     1261 cttgattaaa ccatttgtac gtgataaaga tgccatccaa gccgttcttg tcgttgctga
     1321 actcgctgcc tactaccgtt ctcgtggttt gacacttgct gacggtatcg aagaaatcta
     1381 taaagaatat ggctactacg cagaaaaaac aatctctgtt actctttcag gtgtcgatgg
     1441 tgctgaacaa atcaaagcga ttatggctaa attccgcaac aatgctccaa cagaatggaa
     1501 cgcaacagct atcactgtcg tagaagactt caaggcacaa actgctactg ttgctgacgg
     1561 tactgttaca aacttgacaa ctcctccaag tgatgtgttg aaatacacac ttgctgacgg
     1621 ttcatggatt gccgttcgcc cttcaggtac agaaccaaaa atcaagttct acattgcagt
     1681 tgtaggggaa accaacgaag aatcacaagc taagattact aacatcgaag cagaaatcaa
     1741 tgcatttgta aaataaagac ctataaaaga tgagaccaac caacctcatc ttttttcgta
     1801 tcaaatctaa gcaattttag aaactttatg gcatactaga cttatcaatg aaagcgaggt
     1861 aatctcatgg aacaattttt agataacatc aaagaccttg aagtcactac agttgtgcgt
     1921 gcgcaagaag ctcttgataa aaaagaaact gcaaccttct ttatcggtcg caaaacttgc
     1981 ccttactgcc gtaaatttgc aggtacattg tcaggtgtcg tagctgaaac caaagctcac
     2041 atttacttca tcaatagtga agaaccaagc caactcaatg atttgcaagc attccgctca
     2101 cgttatggaa tcccaactgt accaggtttt gttcatatta cagatggaca aatcaacgtc
     2161 cgttgcgact cttcaatgtc agcacaagaa atcaaagatt tcgtaggatt gtaaaaaatc
     2221 agctaacaag tcttaaaatc acaaaaacgc ataatgtaag gtgcaaaaac cttgatatta
     2281 tgcgttttat tgttcctaaa acagttacat cagcatttca ttacagaaca ttttaatttt
     2341 ggaagtcaaa tcaattttta acaatgtttt agaaatcaca gtgggctatt ccatattcaa
     2401 ttatccagat tcaatcgcta ttatcgtttt cctagattac aaaaaaacta cgttttgcta
     2461 atcaaaacgc agtttcagcc actattttat cttactgtcc ttcttttact tctttggttg
     2521 ctacatcttc tccaaaccat ttttggctga tttcttggaa cttgccgtcc ttgtaaagac
     2581 tagaaaaagc ttcatttatc ttcttaacca agtttgtatc ttccttacgg gctccaaccg
     2641 caaaagcttc tgtttctagt ccaactgtaa agacattata atcgtttaaa acaccttctg
     2701 cttctaaata atagtttgca tagacacggt caatcaatag accatcaatt cgatcgtttt
     2761 tcaaatcaat caaggcttca ttaaaggttt ggtattgatt cgcttcctta ttagcgacaa
     2821 tattcttcaa aatttctgga tttgcttcaa agtccacata accagatgaa ccagcttgag
     2881 ctcctaatgt ctttccagtc atatcctttg cagtcgtgat accagatgat ttcttcgtaa
     2941 ccaatacctg ctcattcttc atatatgagt tactgaaagc caccttttca cggcgttcgt
     3001 ctgtagcgga atagccattc caaatcagat caatcgttcc ttttgtcaat tcagcttctt
     3061 tcaaatccca atcaatcggt tgccaattta ccgtgattcc gtatttttca aaaacagctg
     3121 tagctaaatc aatatcaaat cctgcataag aaccatcttt ctgagcaaat cccattggaa
     3181 caaaagtact atcaaatcca atagtaatag acttgttaga ctggtacttt gaccaattat
     3241 ctccactagt ttcgctagaa tttttcccac aagctactaa gaacaaagca gtcatcagac
     3301 tgactaatac aagcatccat tttttcatcc atttttcctc ctatttaggt tctactttca
     3361 ataatacatc tgcgatattt tcagcaaact gcaaatcatg ggtaaccaca atctgggtca
     3421 tcccaagttc cctattttgc aagattagct tctccacttc caaacgtaat tctggatcca
     3481 gggcagaagt tggttcatcg tagccaatga tttctgggtc aatcatcata gcacgcgcca
     3541 aagccacccg ctgcttttgc ccaccagata gtgagaaagg ataggcctct gcgtgtcctc
     3601 ctagtcctaa ctgttccaag agtccactcg ccttcttctc agcctcttcc tgcttcattc
     3661 ccatggtctt cacaggcgat aaagtcaaat tttccagaac tgatagatga ggaaatagtt
     3721 gaaaatcttg gaagacaaat cccagtagat tgcgcttctg caattcatcc agctctaaag
     3781 gttgtccatt ataaaagatt tgccctgaat caatggtttc aagacctgca agcatacgta
     3841 aaagagttgt cttacctcca ccagaaggtc caacgatagc caggatttgc ttttcaggaa
     3901 tacttagact gaaattagac aggatttgtt tgtctccaaa gactttattg atatttcgta
     3961 attctaacat ggcagcctcc tatctataat aactatactt cttctcaact tttttggaaa
     4021 taattgtcac aatcccaatc aaaatcaaat aaatggctcc tgccaagaac ataggaacta
     4081 gactagcatc gcggttagca gctgttcgac tagccaagat aaggtctgaa attccgagag
     4141 catagaccaa agaagtatcc ttgaccaaac tcataacttc attaaagaca ctaggaagaa
     4201 cgatcttggt cacttggggc aagataatat agcgcactct gtcaaaaggg ctaaacttca
     4261 agaccttggc ggcctcatac tgtcctcttg gaatagtgtc aattccccca cggaaaattt
     4321 ctgcaaagta agctgcatag ttgagaacaa aggcaataat agctgcagga aggcggtcta
     4381 aacgaatccc aatacttggg agcacataat agataaaaat cagttgcaag agtaaggggg
     4441 ttcctcgcat aacccagatg taaatgttaa tcagataatg gaggggcttc caatggactt
     4501 gcaaggcaaa ggcaatcaaa acgcccaagg gaatcgaaaa tagcaagacc agtgcaaaga
     4561 cctgtacagt cgtgctcgca ccattcagta aactcggtaa tatctcaaat aaataagaca
     4621 tactgcacct cctaaaagta attgttccta ttatagcatg aataaacaag attaccaagt
     4681 atttttgtaa aaagattcta ccatatacaa ataaaaaccg tagctatcaa aagagataaa
     4741 ctacagttct atatgtttaa acattcttac aatctctcaa acagttcttg catttgcaca
     4801 tcatctggaa ccagttttaa gtaagtgtga gcatggactt ttgcttcttc aaaatgtccc
     4861 aattcacgca agagatagat atagtgttcc agaaattctg gattgtcctt caaatctcct
     4921 gtcaactctt gataatgctc ataagcagta tccaaatcgt ccatttcttg ataagaacga
     4981 gcaatcatcc acttggtcaa aagattttct ggctcctcac tctgcaagtc tagaatatcc
     5041 tcataacgct cctgctccag ataaatagtg gctaaacgaa gcaagatttc ttctgtatcc
     5101 tcagcgtctt cttttgcagc aagaagataa ttttctgcac cactagcatc atgcaattca
     5161 taagaaaatt gtgaagcagc cagcaagagg cgagtttcaa agggattttt ctctaatcct
     5221 tgcttagcga tacgcagggc ttcttgaact tgatgttcct tatgtaaagc ctgactgtac
     5281 ccatactcat agccttcaaa gtcaggagaa atggtatcaa gctgcttaaa gtagagggtg
     5341 gctttttgat attcttcttg atcaaaataa agactggcca actcaaaagc tgttaagtca
     5401 tcgtattcta actccagggc tttttctaaa aactcagtag ccgtttcaaa tttccctaac
     5461 tgagcatagg caaagccaat tcgttgatag gtggaaatgc ccgtttgctc ataaatcgag
     5521 cgattatcta actgggcata ggcttgaata gccgcttggt aattttccaa ctcactatcc
     5581 aactctgcca aacccaacat caagagagaa tcctctgagt aggtcaaggc ctccaataat
     5641 ttctcacgtg ccacatctgt caaaccttcc agctggtaaa ggtctgcctt caaaaccaaa
     5701 gacgagacat accagtcact gtcagcttgg atttcctcaa gataggtaaa ggcttcttct
     5761 atttgaccat cctcgctagc aattgcagct agattaagat gaacctctgg aaaatcctct
     5821 acaattttca ggtaaatttc cttggcctga ggatagaaac caatcccttc aagataagtt
     5881 gccaactcat acagaagatc acttgaatca ttttctaaag ctttggcgaa ataatactca
     5941 gccttagtta aatcttgctc ctccaaagcc tgtaacatct gttgactatt gttcactctt
     6001 gacttcctca ccctctaatt catataggcc actgattacc ttataccatt cgaaaatggc
     6061 tgaaatgaca accttagcag aggcataaac cggaataccg agcaagactc cccagatacc
     6121 aaacatggat cctgaagtta gcaagacaaa gagaacatta atgggatgga tgtttaattg
     6181 acttcccaaa atcaatggag aaacaaaacg gccttcaata gtttgttcta cgataaagac
     6241 aatcactact ttcaaaagca tgactggccc agcaatcaag cccaatacta gggcaggaag
     6301 catggctagg aagctgccaa gataaggaac caaatttaaa ataccagcag taacacctag
     6361 cgtaaccgca tagcgtagac cgataatctt gaagaaaatc ataaacatta ctgctacaat
     6421 aatagctact gtcacttgcc ctcgaacata gttggacaac tgttgattca catctgacaa
     6481 aacctgtcct acaggttctt tcaattttgt cggcatgaat tgggtcaaat agttacgcaa
     6541 gccttttcca tcacgcaaga gataaaagag catgaaagga acaataatca aggcaacaat
     6601 cacttgagaa gccccgctaa taaaggcact cacccagttg actgcctgag atgaaacctt
     6661 actcgcccaa actgtagcct gacttgagaa gtttgtcaaa acttgttcta actgaggtct
     6721 gaaatcatct ggcaggtgct gggctaccaa tccattaaca atcctatcta tatcttctaa
     6781 gtaaacagga acgtttcttg caaaggtcaa aacctgacgt tgcagatttg gaatggcgac
     6841 tgccaagccc caaatgataa agagagctat gatgacaaag acaatgctga tggctatgac
     6901 gcgattgact ttgtgttttt ccatccaatc aacaatagga ttcaacaaat aatataacaa
     6961 accagacaga atgactggca acatcacaac tgctaaaaag tctaaaacag gtgaaaatag
     7021 aaaactaatc ttacttaaaa taaaaagatt gagtcccaat aataaggtta ccaaaaatac
     7081 cgtaatggcc ttgttatcca aaaaccactt gaaaaaccaa gataggctaa aatgtttctc
     7141 tttttgctcc ataaatactt cctttctatt gttctcccat tataccattt ttgaaacaaa
     7201 ataactcttt tttaaagtgc ttacatctaa ttggatgtct ttaattggct tgtttttgtg
     7261 atataatagt cttatcttta cacagaggta tagtaatgaa agaaactgtt tattttggaa
     7321 cttatacacg tcgtacttct caagggattt acaaggcaga ctttgataca gaaactggtc
     7381 agctttcaaa tctagaactt tttgcagctg agccaagtcc aacctacctt gcctttgacc
     7441 agcaccaaca tttatacact gttggtagcc aagacgataa ggggggaatt gcagcctatc
     7501 aaactgacgg gactgtgtta aatcatgttg ttgaagaagg agctccccac tgttatgttg
     7561 ctgtcgatga aaagcgtgat ttggtttacg cagccaacta tcacaaggga caggtccttg
     7621 tttataaacg ccaggaagat ggtagtcttc tacttagcga tatggatcaa cacagtggcc
     7681 aaggtccaca tgaaaatcaa gcttcccccc atgttcacta tacagattta acacctgacc
     7741 actatctagt gacctgcgac ttgggaactg accaagtcat cacctatgac ctcgatcaag
     7801 aaggaaaatt atctaagctc tatacctatc acagcaagac aggagcaggc tcacgccata
     7861 tcattttcca taaccactat aaaatcgctt atctcatttg tgaactcaat agtactatcg
     7921 aagttttaat ctacgatggc gttggcgaat ttgaacgtat gcaggtcatt tcaactttac
     7981 cagaagctta cgaaggcttt aatggaaccg ctgctattcg tctctctaca gacggtcaat
     8041 acctctacgc ttctaaccgt ggtcataatt ctatcgcagt atataccatc cttgcggacg
     8101 gtagcttaga gttattagaa atcgttccaa cacatggtca gactccacgt gattttgatt
     8161 tgacacccga ccaaaaattt ctcattgctg tccaccaaga ctctgacaat gcaactgtct
     8221 ttaaacgtaa ttgtgacaat ggtcgtctag cagaactctc caacgacttc catgttcccg
     8281 aagcggtctg tatccgtttt gctccttaag aaaacataaa aaatgaactt ggaattttca
     8341 agttcatttt tttcttatag tctatttccg acattgatac ggttaatggc acgttgcagt
     8401 gcaatcttcg cacgacgttc ttggtcaatc aagtgtttgt cttgtgcttc ttcaattgca
     8461 cgttctgcac gaagtttggc acgttctgca cgactgatat cgatatcacg agcacgttct
     8521 gcagagtcag cgacgattgt aatcatatca ttggcaattt caataacacc gccgtttact
     8581 gcaatccagt tcacgtgatc ttcgtcatca atacgtttta cctttacttc atcaactgct
     8641 aaaaccgcaa tcatattttc atgtcgtggc aagatcccca tctcaccatc cagagttcga
     8701 accgatacat agctggcatg gtgatcatag acgaggccat ctggtgtcac gatctggaca
     8761 gttaactgag ccatagatca cctcttaaaa tcccattttt tcagcttttg caatcacatc
     8821 ttcgatagaa cctacaccac ggaaggcatc ttctggcaag tggtcgtatt taccatcaag
     8881 gatttcctta aagccacgta cagtttcagc aactggaaca taagaacctg gctgaccagt
     8941 aaattgttct gcgacgttga agttttgtga caagaagaac tggatacgac gggcgcgagc
     9001 aaccaagatc ttttcttcat cagaaagctc atccatacca aggatagcaa tgatatcttg
     9061 caattcatgg taacgttgaa ggacacgttt tacttcagca gcaactgcat agtgctcttc
     9121 tccaacgatt tcaggtgcca aggcacgtga gcttgaagca agtgggtcaa cggctgggta
     9181 gatacccaat tgtaccaact tacgttccaa gtttgttgtt gaatccaagt gagcgaaggc
     9241 tgttgctggc gctgggtcag tatagtcatc cgctggcaca tagatagcct ggatagaggt
     9301 tacagaaccc ttcttggttg atgtgatacg ttcttgcaat tgacccattt ccgtagcaag
     9361 tgttggttgg taaccaacgg ctgatggcat acgacccaaa agggcagata cttctgaacc
     9421 agcctgagtg aaacggaaga tattatcgat aaagagaagc acgtcttggc cttccacatc
     9481 acggaagtat tcagcgattg tcaaaccagt aagggcaaca cgcatacgtg ctcctggtgg
     9541 ctcattcatc tgaccaaaga ccatggctgt tttctcgata acgcctgatt ctttcatttc
     9601 ccagtaaagg tcattcccct cacgagtacg ttccccaaca ccagcaaata ctgaaatacc
     9661 accgtgctct tgggcaatgt tgtgaatcaa ttcttggatt aagacggttt taccaactcc
     9721 ggcaccaccg aaaagtccaa ctttaccacc tttaaggtaa ggggcaagaa ggtcaataac
     9781 cttgatccct gtttcaagga tttcagaaga ggtagacaac tcatcaaaag ttggagcttt
     9841 tttatgaatt ggctgacgct ctgcgtcttc tgtaaaagga gcttccaagt caatggtatc
     9901 tcccaaaacg ttgaagacac gtcccaaagt ttctttacct actggtacag agattggacg
     9961 acctgtgtcc aatacttcca ttccacgagt caacccatct gttgattcca tggcgatagt
    10021 acgaaccata ccatctccta actccaaggc tacttcaagg acgatttttg tttttctttc
    10081 gtcatttttg tagacgacaa gtgcattatt aatctcagga agtttttccc ctgctgcaaa
    10141 caaaacgtct acaacgggac ccataacctg agcaatttta cctgaactca tctccttctc
    10201 ctattctata taagatactg tcggttccta gctcaactag gtcctaagtt cattttcata
    10261 cgagatggac tagagcctat tctaaggcac tagcacctgc tacgatttct gtaatttctt
    10321 gtgtaatcgc cgcctgtctg gcacggttat actgaattgt caaatcattg atgactttct
    10381 tagcattatc tgtcgctgtt tgcatggctg tcatacccgc agcattctca gctgtcttgg
    10441 catcgataat ggcaccgtaa atcatacttt ctgcaaactg aggcaacaac tgctccagaa
    10501 tttcttctcg gctggtttcc aattcaaaag tcaagctgta ctcttcatcc gcttcatttg
    10561 gatccaagtc aacaatcgga agcatttgtt ccacacgcat ttgactggtt agcgtattga
    10621 catggtggtt gtagcaaaca taaagctcat caaagagttc attttggtac atttcaacag
    10681 tttttgaaat aatcttacga acttgatcaa agctaggttg gtctgacaag ccacgtaatt
    10741 cataaagtgg ttgaataccg cgagccttaa agaaatcagc tcccatccca ccgatacaga
    10801 tcatttcaaa acctttaccg tctgggtggt attcttcttt caactccata acagctttca
    10861 aaatagagga attataacct ccaaccaaac cgcggtctga agtgataacg atatagcctg
    10921 tcttcttcac agaacggcta atcaacatcg gattagttga agcaccagct ccattaccat
    10981 gaaggatatc tgtcaaaagt ttacgcactt tctgagcgta aacttggaag ttgcgagcag
    11041 cttcttcaga acgacctagc ttagcagccg ataccatttg catggcatta gtgatttgac
    11101 tcgtattttt tgttgaggcg atttttgttt taatatcatt tagagatact gccatctgac
    11161 acctctattc ttattggaag ctagattgat tgagaaactc tgtaatcgca gcatccaaga
    11221 ctgcttcttc tggcaagtct tttgtatcac gaatggtttc caaaatctct ggatgttgag
    11281 catcaaagaa ggcatggaac tcttcctcga aacgaacaat atcatctact ggaacagtat
    11341 ccaagaaacc atgtgtcaaa gcataaagaa tggttacttg tttctcaaca ggtaatggtt
    11401 tgtgaacagg ttgtttcaag acctcaacgg tacgacgtcc acggttcaac ttagcctgtg
    11461 ttgctgcgtc caagtcagaa ccaaacttag taaaggcttc caactcacgg tatgaagcaa
    11521 ggtcgatacg aagtgtacca gcaaccttct tcatggcttt gatttgtgca gaaccaccta
    11581 cacgagatac agatgaaccc gcatcgatgg ctggacgaat acctgcattg aaaaggccat
    11641 cgccaaggaa gatttgtcca tcagtgatag aaatcacgtt ggttgcgata taggctgaga
    11701 tatctcctgc ttgtgtctcg ataaatggta gggctgtaat tgatccacca ccaagttcat
    11761 cagaaacttt agctgagcgc tcaagcaaac ggctgtggag atagaaaaca tcccctggga
    11821 aggcttcacg acctggagga cgacgaagca agagcgacag ttcacgataa gctaccgctt
    11881 gttttgatag atcatcgtat acaatcaaaa catgcttacc ttgatacata aattcttccg
    11941 ccatagcaac cccagcataa ggagctagga agagcaatgg agatggttgt gaagcagagg
    12001 ctgtcacaac gattgtgtag tccaaggcac cgtactgacg aagtgtttct acttgcgtac
    12061 gaactgttga ttctttttgt ccaatcgcga cgtagataca gatcatatct tgatcttttt
    12121 ggttcaagat tgtatcaatc gcaatggttg ttttccctgt ctgacggtca ccgataatca
    12181 actcacgttg accacgacca atcggtacaa gggcgtcaat agctttcaaa ccagtttgca
    12241 atggttctga aacagactta cgttgcataa caccaggagc tggtgcttct actggacgag
    12301 ttttatcagt gtggatttct ccaagaccgt caactggacg accaagcgga tccacaacac
    12361 gaccaatcag actttcacct acagggactt ccatgatttt ccctgtacgg cggattgtat
    12421 cgccttcacg gatatctgta aagtcaccta ggatgataat accaacgtct gttgactcca
    12481 agttttgagc cataccataa gagccgtttt caaaattcaa caactctcca ctcatggcat
    12541 tttcaaggcc gtgagcacgc gcgataccat ccccgatata ggttacaaca cctgtttcag
    12601 tcacatcaaa attgggtttg aaattttcaa tttgttgctt aattaaagcg ctgatttctt
    12661 gtgcgttaat tgccaaaaga acaccacttt ctatttcaaa ttttctttaa caactttaag
    12721 ttgttgttta atactcacat caattgtctt gtgattggca aaaatgacaa aaccaccaat
    12781 gagactttca tcgatttgtt cttttacact ccttactttc agagacattt ttttctcaat
    12841 caaagggagc aaacgagtct tctgttcatc agttagagga taagcagacg taatcgtcac
    12901 ttcaaatcga tttgtttctt tttcaagtcg gttcaagcaa tctacaagca catcataaaa
    12961 aagatttgct ctgtgattgt aggccagaac ctggataaag ttttgtaata aaggtgacac
    13021 agaatcttgg aaaaaagcaa ttgttttttc cttatccgac tcgtctactg ccacttgttt
    13081 taaaaaagaa ggcagacctg ttttttcaac aacttgcttg atttgagtca agtctgaaaa
    13141 gatacggtct tcttctcctt tttcaagtac caattggaca aaaggcatgc tgtatttttc
    13201 aattaccttt actgttttct tgtccattaa gcttctccta gctgatcgat atactgatca
    13261 atgagtgctt tatgggcatg actgtcaagg ttttgtgaga tgattttacc agctaagctg
    13321 atggtcaaat ctgcgacctc acccttaaca ctctgtaaag cttctacttt attttgagca
    13381 atttcttgat tggctttttc ttttaagtgt cctgcttcta gtttagcatc tgctaagata
    13441 ttagccttac tttgctcagc tgtttccttt gcattttcaa tgattgtctt agcttcttta
    13501 cggctaccag ctaattcatc ttcgcgtttt tgagccaata cttctgcttt ttgacgggct
    13561 tcttcagctc tgtcaatatc tgaagcaatt ttttcagctc tttcttcgaa aatgcctgta
    13621 atattagacc atgcaaattt tttaatcaag actagcaaaa gaataaaaga gccagtaatt
    13681 aaaacaaaat taccaattaa ttcacctact gttacgtgca tcagttactc ctttctattc
    13741 ctcttcaata ttaatcttat tccctaaata cacagatgtc aaaagagtaa aaacataagc
    13801 ttggatgcag gaaataaaga cagaaaatgc agtccaagcc aaattagctc caaaggctac
    13861 tggataccaa taaatagctt ggtgggaaag aagaagtaac aaactcgtca tgacctctcc
    13921 tgcaaagata ttcccaaaaa tccgcaaagc caaagataag aagtttgtaa attcttccaa
    13981 gatattcatc ggtatgacaa aaacaggact cataaaagat tttatacttt ttttaaatcc
    14041 acgacgacga acgctttcta tatgtgtcaa caaaatgaca agaaaagata aggttaagtc
    14101 atactgtaaa ttagcggttg gcgaactcca ccagttagtc ccatcgatcg tttgaagctt
    14161 tgtcattaag ccaaggttat tggcaatcac catgaaaagg aataaacaaa ggaaaaagag
    14221 tgagtaatct ttcatgtagc gcgaaccaat gttaggttct gtaaatccaa taacaaaatc
    14281 atagacatac tcaagtacat tttgctttcc tttgggtttc aaggtcatat tgcggcttgc
    14341 ccaataaata aagacaaaaa taactcccac aatcaacaaa gtcatggcta acatagtcag
    14401 attgaagata acaggaccaa tagagatgat tggattaata ctttcttcca tctaaaatcc
    14461 tcccttttct tctcgttcca tgtatttatt tgataataaa tgagaagaca agagttacaa
    14521 agaaagttcc ttcaataaag gcaacaccta aaaacatcaa actacgaaac tcagaaagca
    14581 tatctggttg gcgtgctact gatttaaaca gtccattcat caataaacct tcaccgacag
    14641 atacgcccat acaggcaata cataagccta aaaatgttaa attcataaca aattctcctt
    14701 taaaataaaa tttacttact tagtgtagtc ctaaaattta aatttgtcaa cttttaaccg
    14761 ctattggaag cgtttaataa aaattatttc cattttgcta aatttcaagt tcaagttagc
    14821 catccagaag tcttctctgg gtgacttgta gtccaagcat tttttaggat agttgttaat
    14881 ccacttttcg atgaatgcga cttctttggg agtcattttc ttggttccct taggtaacca
    14941 tctacgaatg aacctgttgt gattctcatt agttcccctt tcccaagagg cataggggtg
    15001 cgcataataa atgtgctcct cagaaaatac atcagacaag cgattgaatt ccgttccatt
    15061 atctgccgtg atggaaagaa tcttgtgttg ttttaagatg agttttagag cctgattgac
    15121 cacctcagca cttttatttg gaatcaatcg gatgatctga tgtctactct ttcgatccgt
    15181 caagacaagc aagcagtagt ttttcgatct cgtaagtaga accgtatcaa tctcataatg
    15241 cccattctcc aagcgaagat tgatagcttc aggccgctgt gcgatggatt gaccagcagg
    15301 tttaaagttg gtgctagcct gtttcttaag cgcttttcct tttctagggt aaagcagatc
    15361 ctgcttgctt aaccccaatt ttccacgatg aatccaatag taaatggttg aaattcctac
    15421 gttaacccct ttagccatca ccatcatttc aggcgaaaat ttttggttat gatagtggag
    15481 aatcttttcc tttagttcct tggtcaagct tgatttcttg accgagcgct tgcgattgtt
    15541 ttcataagac tgttgagcat agtcggcaga ataaacctct ttgaagcacc cttttccaag
    15601 acattgtcgg actgtcccac gcttgatttc agtgtggata gtttgaggag cttttccaag
    15661 tagagaggca atttctctat ttgatttccc ttcttttttc catcgttcta ttaagcaacg
    15721 gctatcgatt gtcaaatgtt tgccttttgt agtataatag ttttgcatct ctgtgccttt
    15781 cttgtgtttg tggttgaaca acaagtatag cacagaggtg ttttcttatg cctacaagag
    15841 ctttcattat ttccactttc tttcggattt cactctattc tgaaaaactt gtgtatattt
    15901 actgaagcta gcaagtctta cctgtaaatt taatgaaagc aacacaaaat ccgagagggg
    15961 aatctcggat taatgtcaat ttaaaaagat agagagtttt tagtttaaat aaattgtttt
    16021 aaaatatcaa caacatcact tcttttctta acctgataag ccttaattcc taattttggg
    16081 gctacgatta tattgtcctc aatatcgtct agaaagacac aatttctagg ttataactgg
    16141 tatttatcaa tagttattca tatatatcag tccacctcca tactcacctt acagattctt
    16201 ttggtaataa tatctttgcc taatttagag atagtcttgc aaagaaaaaa cttccttgta
    16261 gccatgtttc tgataaaagt ccggtgcctg aaactggtaa gtattgacaa aggcaaaaca
    16321 acaatttcga ttcttagctt cactttctgc ctgttgcaat agttttgaac cgattccttg
    16381 ccctcgcagt tcctctttta caaacaaata ctcgatttct agccaatttc caaaagtctc
    16441 tgctatcaaa cctgccagga gattgccctt ttcatcttcg acataaagat taagtggctc
    16501 actttcagtc tcttctcttt ttgaacggtt ataaacacga agcagattcc ctatttcttg
    16561 cgatttatgt gattccttat tttccaatct aaagtatagt gaaatgaaat aaaacatgcg
    16621 caaatcgatt aaggaattta atctaatttc taacaatgtc ttagaaatca aagtgtacta
    16681 tgttaacttc aatgcactat acatctaata ctcaataaaa atcaaataat actcaataaa
    16741 aatcaaagag caaactagga aactagccgc aggttgctca aaacactgtt ttgaggttgt
    16801 agatgaaact gacgaagtca gctcaaaaca tggttttgag gttgtagatg aaactgacga
    16861 agtcagtaac catacatacg gtaaggcgac gctgacgtgg tttgaagaga ttttcgaaga
    16921 gtagcaaaac agaaaaagga gtgagtgaag cgcatcgcca ctcctttttc tgtttttagg
    16981 ctgttttttc aaccttcaag atttttacat catagctatc aacaggcgtt tcaatggttg
    17041 ctgtgtcacc tgttttcttg ccaatcaagg cctgcccaat tgggctttca tttgaaacct
    17101 tacctgcaaa ggcatccgca ccagctgaac ctacgataat ataaacttct tcttcgtcct
    17161 caccaatttc ttggatgatg actgttttac caatcgctac ttcgtcctgg gcaactgcgt
    17221 cgctattgac gatttcagca tagcggattt ttgtttctaa gctagagatt tgtccttcga
    17281 caaaggcttg ttcatcctta gctgcttcgt actcactgtt ttctgaaagg tcaccgtatg
    17341 aacgggcaat cttaatgcgt tctaccactt ctggtcgacg aaccaatttc aattcttcta
    17401 attctttttc aagtttttcc ttttcctcaa gggtcatagg atatgttttt tctgccattt
    17461 ttctcaactt tcttctgata atattttcta aagaaaatta tgtgaagtat cacataattt
    17521 tagtttgttt agtttaattt gctgttgaca tgttcagcga cattgcggtc gtggtcttct
    17581 tgattgttag catagtagac cttgccttct gtgacatctg ctacaaagta gaggttatcg
    17641 ctcttagttt gattgatgct tgactcaatc gcatccagac ttggactatc gactggacca
    17701 ggcatgagac ctacattttt ataaacatta taaggtgaat caatgttggt atcaatcgca
    17761 acatcctcag ctagactgat attttgcccc agttttcctt gggcatacaa gattgcaata
    17821 ttactttgaa gtggcctatt acgattcaaa cgattgtaga atacacctgc aatgagctta
    17881 cgatcttctg tcttggcacc ttctttttcg accaaggaag caatggtcaa caactcattg
    17941 acagtcaagt ttttagattt gatagtacta tagtaaggag ataggttctt atccatagca
    18001 gctaacatct catcaatcaa gctctcaata gttgtgcttt ccttgataga gtatgtagct
    18061 gggaaaaggt atccttccaa acgataacgc gcaccgctgt cttttacagg caaactttcc
    18121 agtaaagtag gatatttagc tactgcttga ctgataaacg tctcatcttg aactttagcc
    18181 aagaaagtct ccgctgtcaa agactctttg aagtcacctt gcaattgacc cacagcttga
    18241 gcaatctgat ccaaggtata accttctgga attgtcaaag tcgcaagtac aggttcttgc
    18301 ggttcatctg ttccaccttt ttgcaactct ttgagtaagt cttctgtact catactcttt
    18361 tgcaaattgt agtaacctgc tttcaagtcg gtataatttt tatacttggc ataaaaacta
    18421 aaaatcagac catgctttac caaaccagct ttttcaagcg tcgtaccgat ttcttgaacg
    18481 tttgaacctt ctggaattcc aaccgtcaca tatttcttag aattagcatc gataggtaac
    18541 aaagaatcta gcacgtactg gtaaccaaag taaccacctg ctgagagcaa ggcaaggaat
    18601 acaaggaatg aagtcacaaa agctttcaca tgtgacttct tctctttctt aggcttaacg
    18661 ggttttgctc cttctctacg gctacgacgt gatgtatcgc tgatgatatc cactgtttct
    18721 gtagcaggcc taggtgtttc tggacctgct tgttctgctt ttttctctgc cgtcgtatag
    18781 gaaacagcta cccttgttgg ggtttcattg tattctcttt caagtttctt aggtctaaca
    18841 ggacctggac ctggtcttga tccactttct tccgctggag aagaaggtac atcttgactt
    18901 ggatgacttg gaacaccagg agtttctctt tgaatctcat ctgctggaga agctggtaca
    18961 ccttgacttg ggtgagtagg cacggtagga gcttttctca taatctcctc taccgttgac
    19021 aaggaatcag ccatgagttc ctcagctgaa ggttcatttg caggagtgcg aactactgcc
    19081 tcatcttctt tcagaacttc atcatagcct tttacttttt ctaaatctct cagaatctgc
    19141 tctttaaagc ttaatttctc ttcttctctt gacttttcac tcaaaagttt ttcctccttg
    19201 ttgataatcc ataatattat atcttaaaag tcaaaaaaaa gcaatctatg atacttttcc
    19261 taacttattt tttcatttcc cagaccatat cataccatgt ttcccctgca aaggttgact
    19321 gggactggcc ttcgttgaca aatccatgtt tttcataata ggcgatgaga tagtcatgac
    19381 aggttagatt aatgccatct ctctcatctt caagagcaac ttctttcaag gctgtcagca
    19441 atttctgacc cagtccgagt ccctgtgcct ccttggcaat agacagacag gtcacagaga
    19501 tataaccacc aggctcatga ctatagtctt ttatttcttc tgtaaaagac tggtcttgca
    19561 gatggcggtg caggccaact ggtccttcga tataacccat gattcttcct tctttttcag
    19621 caaccagaaa agaggtctga atttctctca aatgtgcttc aaagacagaa ggaggaatgg
    19681 cttcttcgac cgaaaaattt tcaaattcaa gttcaacaat ccgatccaaa tcttctaatc
    19741 ttgcttgtct gattttcatt gttcctccag ataaaaggga ttaaaccaaa tcatactata
    19801 gccctggcta gttgcataga gcaaagttgc gtcttcatca acaaaaccgt tcatttcaaa
    19861 ataggaaagc agctcatcag gactctccaa acgaatccct ttgtaatcca gctcaactgc
    19921 cacctctttc aaggctgcaa gaagaagtgt tcccaagccc tgtctctgat ggtcagactc
    19981 gatgactaaa gaatgtactt ttagatattg cggattgtct gactggggac ttgataaaat
    20041 atagcctaaa agttgatttt catccctagc tagaagaaag gtatccgcac acttacggat
    20101 actttcttct aaaatatggg aaggttgctg cttttcagct ggaaaagacg aggtctgaag
    20161 tgcctctatc tcaggcaaat cagacttgct tgcctgaatg atcttaattg gaatttccat
    20221 gggaacatcc tattgaacat tgcttgtcaa gttagacaag agacgctcaa atgagtattc
    20281 ataggtttgg atgtctcctg ctcccataaa gacgtaaaca gcattgtcat ggtctaggag
    20341 tggagaaaca ttttcaacag taatcacttg gtgttttttg ttgattttgt tggctaggtc
    20401 ttctacctta acgtcaccat gatctacttc acgagccgag ccataaattt gcgctagata
    20461 aacagcatct gcttggttta aagcatggac aaagtcgtcc aacaaggcaa tggttcttgt
    20521 aaaggtatgc ggttgaaaga ctgctacaat ttccttgctt gggtatttct gacgagccgc
    20581 atccaaggtc gcaataattt ctgttggatg gtgggcaaag tcatcgataa tcactgtatc
    20641 attgacaatt ttctcagtga aacgacgttt aacaccggca aatgttttca agtgctcacg
    20701 caccaagttc aaatcaaatc ctgctgtgta aagaagacca ataacggctg tcgcattcat
    20761 gatattgtga cgaccaaagg ttggaatgtg gaattgcccc aagttttgtc cacggaaatg
    20821 aacagtgaaa gttgaaccag ttgttgaacg aagaagatca ctagctacaa agtcattgcc
    20881 ttcagattca aaaccataat aataaattgg tgcatcagac gtaatcttac gcaattcagc
    20941 atcttcacca tagacaaaaa gacccttggt aatttgtttg gcatagtcgt taaaggcatt
    21001 gaaaacatcc ttgagacttg tgaaataatc tggatggtca aagtcaatgt tggtgataat
    21061 agagtattct gggtggtaag gcatgaagtg acgctcatat tcatcagatt caaagacaaa
    21121 atatttggca ttggccgaac cacgacctgt cccatctcca atcaagaagc tggtatctgt
    21181 aatgtgagac aagacatgag acaacatacc tgtcgttgaa gtttttccat gtgctcctgc
    21241 tactcccatg ctaacaaagt cacgcataaa gctacctaga aactcatggt aacgtttgta
    21301 gctgatacca tttttgtccg cataggcaat ttcgacgttg ttatctggac gaaaggcatt
    21361 tccagcgata atttccatat caccgtctag attcttttca tcaaaaggaa gaatggtaat
    21421 tcctgcctgc tcaagaccgc gttgggtaaa gtagtacttt tcaacatctg atccctgaac
    21481 cttgtgcccc atctggtgca acatcaaggc caaggcactc atccctgatc ccttaattcc
    21541 gataaaatga tatgtctttg acatgttttc tccccctatt ctgtcattct ggtcagattc
    21601 aactcttggg caacccgacg ttcttgttct gtttgtttac tttttttatt gtagatttgg
    21661 ctcttcttta gaaaatcata attgtttttc tttggagcag gtgctgacac ttcttcattc
    21721 ttggtaggga tagaatgaac ttcttccgcc aagatataat gagactgggt caatttttgg
    21781 ctatatttga caaattcacc aggattttcc ttttggaaag gagttgtcgg ttgattgccc
    21841 tgtctaacta gactgggctg agaatgacgt ctcgcaaggc tgaaatcctg agttaggtag
    21901 ttagcagagc gtttcttttt caagtccgca cgcgcttctt cacgcgccac ctccgcatag
    21961 ctctttcctt cttttttaac ccctaaagga gcctttttag gtttctcgac ttgcttttca
    22021 atcggtttta ctggtttttc ttcagcaata ggagcccatt ctaaataatt tttatctcga
    22081 tactcaccct tgatattact gatcagatca gactcatcat agagattcat gactggcatt
    22141 tcagtcaaca tgacctcgtc atctgacacc aatggaaatc gttcttgttt cattttctat
    22201 ttcctttcaa cacttcatta tagcgtattg tcttgatttt tcaagtgctg gcttcagaaa
    22261 ttcccaaaat ttctctaatt tctgctaggg tcagactacc acgtgactct gtgccgtcca
    22321 atacttgtga caccagatgt ttcttttgtt cttggagttc ctgaattttt tcttcaatgg
    22381 ttcccttggt caccaagcga tagacctcaa ccgtttcttc ctgacccatc cgatgggcac
    22441 ggccaatggc ttgcgcttcc accgcaggat tccaccaaag gtcaaccaag atcactgtat
    22501 ctgcacctgt caggttcaga ccgaccccac cagccttgag ggaaatcaga aaggcatctc
    22561 tttctccttg attaaaggcc ttggtcatgt cttgtctttc cttggctggg gttgaacccg
    22621 taattttaaa ggaagtcagg cccaagtctg gcagttcttg ttcaattttt tccaacattc
    22681 ccttgaactg agagaaaatc aagacacggt gtccgccgtc tgccacctgt accagtaggt
    22741 ctcggagact atctagtttg ccactgactc cctgataatc ttccataaac agggtaggag
    22801 tgtcacatat ttgacgcaag cgcatcaaac cagataaaat ttccacacga cttcgctgaa
    22861 attcctgttc tgacacttga gccagatggt ctcgcatctg ttgtaactgg gcaaggtaaa
    22921 tagccttttg ctggtcttcc agttcatttt tataaaccac ctcaatcaag tctggcaatt
    22981 cagtcagaac ttcttctttc ttgcgtcgca tcacgaaagg cttgataaac tgagccactc
    23041 gctctgctgg caatttcata aattctttct tgcttggcaa aagtccgggc atgacgattt
    23101 ggaaaataga ccacagctca cccagatggt tttcaatcgg agttcctgac aaggcaaaga
    23161 ccgacggcac cacaaattgt ctcaaggtct gggcaatctt ggtctgggca tttttcatga
    23221 cctgagcctc atctaagaaa aggaagtcaa aggccatccc ctgataaaac tcactgtcct
    23281 gacggaaggt ggcatagcta gtcacataga tttgatggct ctcggcaaga atctcctcac
    23341 gacttgcttt caaaccatga acaacagcca catccaactg tggagcaaat ttctgaaact
    23401 catctgccca gttgtaaatc aaacctgacg gagcgagaat caaaacccga ctttcttttg
    23461 tcacttgact agtcaaaaaa gcaatggtct gaagggtttt cccaagtccc atatcatcag
    23521 ccaaaatccc accaaaacca taatgatgga gcatctgcaa ccagccaatt cccttttcct
    23581 gataatctcg caagtcagcc tgaacctgag ttgcctgtcg aggaaagtcc tctggatgtg
    23641 tcaaatcctg ggccagattc tggaattctt gtgaaaaaga aacacggtct cgcccttcaa
    23701 agagatgagc taaactgtag gccaaggatt tcctagcctg caaagtccca tcttttaatt
    23761 caaattgccc cagttcctgt aaattttgac gaattttctt ggtttcttca tcgaaaaagt
    23821 aaacttgatt agacgaatca atataaaaat cctgattggc aaccaaggcc tgcatggctt
    23881 ggtcgatttc ctcctgggca atatcttgaa aatcaaactg gatttccaag agacctccct
    23941 tggaggcaat ctgcacctga ggactcgcta ggctataaag ctcttctagt ttatctgata
    24001 ggtcaacatg cccgagtttt tcaaagactg gaatgatatc atgaaaaaaa tgatagacag
    24061 actccgcttt taaggcctga cgccaagatt gaaaatcggc ttcaaagccc gcagccaaac
    24121 agacttggaa aattctttct tctaagtccg cgtcacttga aaatggtaat tcttctagct
    24181 cttgtcggct agatacctgt ctatttccat aatcaaactg aatttctaaa cgaatccgat
    24241 tatcttcttc cctgtcaaag taaaaagagg gcgcaaaagt tttgatttgt agacgttctg
    24301 gagctgaaac ggtgcccatc tggataaaaa gagtcagaca ggaggccaat ttgtctcgat
    24361 cactgctatc aaattgcagg tatttctttc cttgttgacc cacaggtaac gctttaattt
    24421 ccttgagaag acgcatctgc tggtctgtta aaaaataaac ctgaccttta tggaaaagta
    24481 ctgctccttg ataaaagaca ttgaccctag gactctcact gatttccatt tcaaaatagt
    24541 ccgagtattc tgttactgta aaggcaaata gattggcatc agcatgcata tcctgaaaaa
    24601 gcagggtttg gtagctatcc acttgatggt caaattgaaa atggggcaag gccatcagta
    24661 aattcacacc ctgctcaaaa aaggtcagag ggaaaaagag gtgccgacct tggttttgga
    24721 aaaagaggtc tggaaccagc ccttcctccg ttagtccgtg caagaaagtc aaaagttctt
    24781 ggctggcatc atcaaaggct tcccaagaaa gagactcctc ataaatcttg ccaatcatat
    24841 acgactttct ctgctcgaca atccttaaaa aaagtggaat atcccgaatg acatagtatt
    24901 tttggctatt gatttggccg attctcagag tccacaagat atgattggtt cctgcttcca
    24961 cctgacccac agctgataac tcataggcgc atcctgattt tggagataaa attcgatcca
    25021 aaaacttgcc acccaaggtc accttggttt caacggcctc tttttcttca tgaccttctt
    25081 ccagactcca caagatttcc tgaccacgct catcattttt tagaaaatgc tctagcgctg
    25141 ccaaatgcac acagtagccc ctcttttgaa aaaaatcaca ggcacaaaaa accaaatcat
    25201 cctctaaact atagcgcagt tcttcttctg caacgcgagc gtagagtcga ttgttctttt
    25261 ccttgatgat atcaacctta ccagtttcat aaagggcaac accttcgata cgaattttcc
    25321 ccggaatcaa tttagccata ttttcacctt taccttatct gtttattata ccatattttc
    25381 gcctatgaaa atagccttct aggaagac
//
LOCUS       DAVDZK010000033        23791 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVDZK010000033 DAVDZK010000000
VERSION     DAVDZK010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.034"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            396..4007
                     /locus_tag="VUX16_001581"
     CDS             396..4007
                     /locus_tag="VUX16_001581"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET8124513.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHA
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVVMSERLVKDDIYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEDAEKATKAEATEEAAEQE"
     gene            4041..7718
                     /gene="rpoC"
                     /locus_tag="VUX16_001582"
     CDS             4041..7718
                     /gene="rpoC"
                     /locus_tag="VUX16_001582"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET8124514.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKVL
                     FNDIMPEGLPYLQEPNNGNLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYQHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIADQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            7819..8232
                     /gene="ndk"
                     /locus_tag="VUX16_001583"
     CDS             7819..8232
                     /gene="ndk"
                     /locus_tag="VUX16_001583"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET8124515.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGTKVIEIWRTMMGATRPEEALPGTI
                     RGDFAKAAEENEVIQNVVHGSDSEESAKREIALWF"
     gene            8466..8689
                     /gene="tnpA"
                     /locus_tag="VUX16_001584"
                     /pseudo
     CDS             8466..8689
                     /gene="tnpA"
                     /locus_tag="VUX16_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            8793..8993
                     /gene="tnpA"
                     /locus_tag="VUX16_001585"
                     /pseudo
     CDS             8793..8993
                     /gene="tnpA"
                     /locus_tag="VUX16_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            9597..10217
                     /locus_tag="VUX16_001586"
     CDS             9597..10217
                     /locus_tag="VUX16_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124516.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIATLIFF"
     gene            10303..10746
                     /gene="tsaE"
                     /locus_tag="VUX16_001587"
     CDS             10303..10746
                     /gene="tsaE"
                     /locus_tag="VUX16_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET8124517.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDTYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            10736..11254
                     /locus_tag="VUX16_001588"
     CDS             10736..11254
                     /locus_tag="VUX16_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124518.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            11262..12278
                     /locus_tag="VUX16_001589"
     CDS             11262..12278
                     /locus_tag="VUX16_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET8124519.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGVELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRVHMLEMQNILRRSLGQEEVTQLETNVVLFEDLFGRAPVG
                     DEDN"
     gene            12362..13618
                     /locus_tag="VUX16_001590"
     CDS             12362..13618
                     /locus_tag="VUX16_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET8124520.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGVSLTGVAGPDSLEGHPVGTVFIGLAQEQETEVINVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            13673..14839
                     /gene="recA"
                     /locus_tag="VUX16_001591"
     CDS             13673..14839
                     /gene="recA"
                     /locus_tag="VUX16_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET8124521.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEASEQDIENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            15164..16534
                     /locus_tag="VUX16_001592"
                     /pseudo
     CDS             15164..16534
                     /locus_tag="VUX16_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
     gene            16910..17866
                     /gene="lytA"
                     /locus_tag="VUX16_001593"
     CDS             16910..17866
                     /gene="lytA"
                     /locus_tag="VUX16_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET8124522.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKVNDTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIAEKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            18231..18391
                     /locus_tag="VUX16_001594"
                     /pseudo
     CDS             18231..18391
                     /locus_tag="VUX16_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            18605..18988
                     /locus_tag="VUX16_001595"
     CDS             18605..18988
                     /locus_tag="VUX16_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124523.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKETVLG"
     gene            18998..19369
                     /locus_tag="VUX16_001596"
     CDS             18998..19369
                     /locus_tag="VUX16_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124524.1"
                     /translation="MTEQLLEKLYSGKIVIPQEVYDEINIPTIPHLKSRIDQLVTKGS
                     AEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLAKKHNGILGSNNLRDVKPY
                     VEEFSLEHMTTGDILVEAFKA"
     gene            19778..20773
                     /locus_tag="VUX16_001597"
     CDS             19778..20773
                     /locus_tag="VUX16_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124525.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELALTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMNVVLVFSKLSDSEKKQLLQARIPFVDFKG
                     NLFFPTLGLVLNADDTEVPKELTPSEQLTWIAFLLTKDQKVVDVELLSRVTGLPNSTI
                     YRCLRTFKALDWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGTYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHALEGKVLEIWKYCPF
                     ISEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEVLENMILQYLGDDDAS"
     gene            20763..21242
                     /locus_tag="VUX16_001598"
                     /pseudo
     CDS             20763..21242
                     /locus_tag="VUX16_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21364..21624
                     /locus_tag="VUX16_001599"
     CDS             21364..21624
                     /locus_tag="VUX16_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124526.1"
                     /translation="MRERSATGAQGLSKFIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTIPQNDDISLDQNEIFQILKNFLDG"
     gene            22160..23098
                     /locus_tag="VUX16_001600"
                     /pseudo
     CDS             22160..23098
                     /locus_tag="VUX16_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23283..23682)
                     /locus_tag="VUX16_001601"
                     /pseudo
     CDS             complement(23283..23682)
                     /locus_tag="VUX16_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         7311 a         4280 c         5286 g         6914 t
ORIGIN      
        1 ttgaaaatga ttttcagtca atagtttttt cagttttttg taccatagcg tgattcgaat
       61 gtgatgccaa gttttctatg ggaaaaaaat taccaaaaac ctactgaatt cccttgaaaa
      121 atctagctaa atagggtata atatgggtaa tcatttgtcg taggttttgt ctgaaatatt
      181 gtccagacaa ggctcacagc agttaaatct tctgaaaaag tcagatttag ctgctctttt
      241 tgtgcttttt ttcaagattt tgagcatttg taacagaggc ttaaagattc tgaaaattcg
      301 tcaagaggac acggtgataa ggggtttaca accatatggc gattagaaaa gcctgattga
      361 caaggcttgg aacttattta caaaggagaa tcatcttggc aggacatgac gttcaatacg
      421 ggaaacatcg tacccgtcgt agtttttcaa gaatcaaaga agttcttgac ttaccaaatt
      481 tgattgaaat tcaaactgac tcattcaaag ctttcctaga ccacgctctt aaggaagtgt
      541 ttgaagatgt attgccaatt tcaaacttca cagacacaat ggagttggaa tttgttggat
      601 atgaaatcaa ggaaccaaaa tacacgctag aagaagctcg tatccacgat gctagctact
      661 cagcaccaat ttttgtaacc ttccgcttga tcaataaaga aacaggcgaa atcaagaccc
      721 aagaagtttt ctttggtgat ttcccaatca tgacagaaat gggtactttc atcatcaatg
      781 gtggtgaacg tattatcgtt tctcagttgg tccgctcacc aggtgtttac tttaacgaca
      841 aagtagacaa aaatggtaag gtgggctatg gttcaactgt tatccctaac cgtggagctt
      901 ggttggaact tgaaagcgac tcaaaagata tcacctacac tcgtatcgac cgtactcgta
      961 agattccatt tacaaccttg gttcgtgctc ttggtttctc aggtgatgat gaaatctttg
     1021 atatctttgg tgacagcgaa ttggttcgca acactgttga aaaagatatc cacaagaatc
     1081 caatggactc tcgtacagac gaagccttga aagaaattta cgaacgcctt cgtccaggtg
     1141 agcctaagac agctgaaagc tcacgtagct tgcttgtggc tcgcttcttt gacccacgtc
     1201 gctatgactt ggcagcagtt ggtcgttaca aaatcaataa aaaactcaat gttaaaacac
     1261 gtttgctcaa ccaaaccatt gcagagccat tggtagaccc tgaaactgga gaaatcttgg
     1321 tagaagctgg tacgattatg actcgtagcg tgattgaaag tattgaaagc catttggatg
     1381 gcgacttgaa caagattgtc tacatcccaa acgatgcagc cgttgtgact gagcctgttg
     1441 ttcttcaaaa attcaaggtt gttgctccaa ctgatccaga tcgcgtcgta acgatcattg
     1501 gtaatgctaa cccagatgac aaggttcgta cggtgactcc tgcagatatc cttgctgaga
     1561 tgagctactt cctcaacttg gctgaaggac ttggccgtgt agatgatatc gaccaccttg
     1621 gaaatcgtcg tatccgtgcg gttggtgaat tgcttgccaa ccaagtacgt ttgggacttt
     1681 ctcgtatgga acgtaatgtc cgtgaacgta tgtctgttca ggacaatgaa gtcttgacac
     1741 cacaacaaat tatcaatatc cgtcctgtaa cagctgcagt taaagaattc tttggttcat
     1801 cacagttgtc acagttcatg gaccaacaca acccgctttc tgagttgtct cacaaacgcc
     1861 gtttgtcagc cttaggacct ggtggtttga ctcgtgaccg tgccggatat gaagtacgtg
     1921 acgtgcacta cactcactat ggtcgtatgt gtccaatcga gacacctgaa ggacctaaca
     1981 tcggtttgat caataacttg tcatcttacg gacacttgaa caaatatggt tttgttcaaa
     2041 caccataccg taaggttgac cgtgaaacag gtgttgtcac gaacgaaatt gtttggttga
     2101 cagctgatga agaagatgaa tatactgtag ctcaggctaa ctctcgtctg aatgaagatg
     2161 gaacctttgc tgagaagatt gtcatgggac gtcaccaagg ggtcaaccaa gagtatccag
     2221 ctaatattgt tgactacatg gacgtttcac caaaacaggt agttgccgtt gcgacagcat
     2281 gtattccttt cttggaaaac gatgactcca accgtgccct catgggagcc aatatgcaac
     2341 gtcaggctgt gccattgatt aatcctcagg caccttacgt tggtactggt atggaatacc
     2401 aagcagccca cgattctggt gcggctgtga ttgctcagta tgatggtaaa gttacttacg
     2461 cagatgctga caaggtagaa gttcgtcgtg aagatggttc attggatgtt taccacatcc
     2521 aaaaattccg tcgttcaaac tcaggtactg cttacaacca acgcactctc gtaaaagttg
     2581 gtgatgtcgt tgaaaaaggc gatttcatcg ctgacggacc ttctatggaa aatggagaaa
     2641 tggcgcttgg acaaaaccca atcgttgcct acatgacttg ggaaggttac aacttcgagg
     2701 atgccgttgt catgagcgaa cgcttggtga aggacgatat ctacacatct gttcaccttg
     2761 aagaatacga atcagaaacg cgcgatacaa agcttgggcc tgaagaaatc actcgcgaaa
     2821 ttccaaacgt tggtgaagat gccctcaaag accttgacga aatggggatt atccgtattg
     2881 gtgctgaggt taaagaaggt gatattcttg taggtaaagt aacacctaag ggtgagaaag
     2941 acctttcagc tgaagaacgt ctcttgcacg ctatctttgg agacaagtct cgtgaagtgc
     3001 gtgatacttc tcttcgtgta ccacacggtg ccgatggtgt cgttcgtgat gttaagatct
     3061 ttacacgtgt aaatggagat gagttgcaat caggtgttaa catgttggtt cgtgtttaca
     3121 tcgctcaaaa acgtaagatt aaggtcggag ataaaatggc cggacgtcac ggaaacaaag
     3181 gggttgtctc tcgtatcgtt cctgtagaag acatgcctta ccttccagac ggaactccag
     3241 tcgacatcat gttgaatcca cttggggtgc catcacgtat gaatatcggt caggttatgg
     3301 agcttcacct tggtatggca gctcgtactc ttggtattca catcgcgaca ccagtctttg
     3361 atggagcaag ttctgaagat ctttggtcaa ctgttaaaga agcaggtatg gatagcgatg
     3421 ccaagacaat cctttacgat ggacgtacag gtgaaccatt tgataaccgt gtttctgttg
     3481 gagtcatgta catgatcaaa cttcaccaca tggttgacga taaattgcac gcgcgttcag
     3541 tcggacctta ctcaactgtt acccaacaac cactcggagg taaagctcag tttggtggac
     3601 aacgtttcgg tgagatggag gtttgggctc ttgaagccta cggtgcgtca aatgtccttc
     3661 aagaaatctt gacttacaag tctgacgata tcaacggacg tttgaaagcc tatgaagcta
     3721 ttacaaaagg caaaccaatt ccaaaaccag gtgttccaga atccttccga gttcttgtca
     3781 aagaattgca atctcttggt cttgacatgc gtgtcctaga cgaagatgac caagaagtgg
     3841 aacttcgcga cttggatgaa ggaatggacg aagatgtcat ccacgtagat gaccttgaaa
     3901 aagcccgtga aaaagcagcc caagaggcta aagcagcctt tgaagctgaa gacgctgaga
     3961 aagcaacaaa agcggaagca acagaagaag ctgctgaaca agaataagca gttcacttac
     4021 gaatagaaag ggaagaaata gtggttgatg taaatcgttt taaaagtatg caaatcaccc
     4081 tagcttctcc aagtaaagtc cgttcatggt cttatggaga agtcaaaaaa cctgaaacaa
     4141 tcaattatcg taccttgaaa ccagaacgtg aaggactctt tgatgaagtg atctttggtc
     4201 ctacaaaaga ctgggaatgt gcttgtggta agtacaaacg cattcgttac agaggaattg
     4261 tttgtgaccg ctgtggggtt gaagtaacgc gtacgaaagt tcgtcgtgag cgtatgggac
     4321 atatcgaatt gaaagctcct gtatctcaca tctggtactt caaggggatt ccaagccgta
     4381 tgggcttgac ccttgatatg agccctcgtg ccctcgagga agttatctac tttgcggctt
     4441 atgtggtgat tgatcctaag gatacaccac ttgagcacaa gtctatcatg acagagcgcg
     4501 aataccgaga gcgcttgcgc gaatatggtt atggttcatt tgttgccaag atgggtgccg
     4561 aagccatcca agaccttttg aagcaagtag atcttgaaaa agaaattgct gaactcaaag
     4621 aagaattgaa aacagctacc ggacaaaaac gtgttaaagc catccgtcgt ttggatgttt
     4681 tggatgcctt ttacaagtct ggaaacaaac ctgaatggat gatccttaac atccttccgg
     4741 ttatcccacc agatcttcgt ccaatgttgc agttggatgg tggccgtttt gcctcatctg
     4801 acttgaatga cctttaccgc cgtgttatca accgtaacaa ccgtttggct cgtttgcttg
     4861 agttaaatgc accaggtatc atcgttcaaa atgagaagcg tatgcttcaa gaagcggttg
     4921 acgctttgat tgacaatggt cgccgtggtc gtccaatcac agggccaggt agccgtccat
     4981 tgaaatcatt gagccacatg cttaaaggta aacaaggacg cttccgtcaa aacttgctcg
     5041 gtaaacgtgt tgacttctca ggacgttccg ttatcgccgt tggtccaact cttaagatgt
     5101 accaatgtgg tgtgccgcgt gaaatggcga ttgaactctt taaaccattt gtcatgcgtg
     5161 aaatcgttgc ccgtgatatc gtgcaaaacg tcaaagcagc taaacgcttg gtggaacgcg
     5221 gagatgagcg tatctgggat atccttgaag aagtgattaa agaacaccca gtgcttttga
     5281 accgcgcacc gacccttcac cgtttgggta tccaagcctt cgagccagtc ttgattgatg
     5341 gtaaggctct tcgcttgcac ccacttgtct gtgaagccta caatgccgac tttgacgggg
     5401 accaaatggc catccacgta ccactttcag aagaagcaca agcagaagct cgtatcctca
     5461 tgctagctgc tgagcacatc ttgaacccga aagatgggaa accggtagtt actccatctc
     5521 aggacatggt tttgggtaac tactacttga ccatggaaga agctggtcgg gaaggcgaag
     5581 gaatggtctt caaagatcgt gacgaagcgg ttatggctta ccgcaatggt tatgttcacc
     5641 tccactcacg tgttggtatc gcaacagaca gcctcaacaa gccttggaca gaagagcaaa
     5701 gacataaggt cttgcttaca acagttggta aagttctctt caacgatatc atgccagagg
     5761 ggctaccata cttgcaagaa ccaaacaatg gcaacttgac agaaggtgtt ccagctaaat
     5821 acttcttgcc acttggtgga gatatcaagg aagctatcag caatcttgaa ctcaaccctc
     5881 cattcaagaa gaaaaacctt ggaaatatca tcgctgaaat cttcaaacgt ttccgtacga
     5941 cagaaacttc tgccctactt gaccgcatga agaacctcgg ttaccagcac tcaactcttg
     6001 caggattgac agtgggtatt gccgatatcc cagtcgttga tgacaaggct gaaatcattg
     6061 aagaatcaca caaacgtgtc gaacaaatca ccaaacaatt ccgtcgtggt atgatcacag
     6121 acgacgagcg ttacaatgct gttacagctg aatggcgtgc tgcccgtgaa aaacttgaga
     6181 aacgcttgat tgctgaccaa gatcctaaga acccaatcgt tatgatgatg gactctggag
     6241 cccgtggtaa catctcaaac ttctcacagc ttgccggtat gcgtggtctg atggctgctc
     6301 cgaatggacg tatcatggaa ttgccaatcc tttcaaactt ccgcgaaggt ttgtcggtat
     6361 tggaaatgtt cttctcaact cacggtgctc gtaaaggtat gaccgatacg gcccttaaga
     6421 cagccgactc aggttacttg actcgtcgtt tggtcgacgt tgcccaagac gttatcatcc
     6481 gtgaggacga ctgtggaact gaccgtggtc tcttgatccg ttctatcgca gaaggaaaag
     6541 agatgatcga gtctctcgaa gagcgtctca acggtcgtta cactaagaaa actgttaaac
     6601 atccagaaac tggtgcagtg attattggtc caaatgaatt gattacagaa gacaaggcgc
     6661 gtgaaattgt caatgctggt gtggaagaag tgactatccg ttctgtattt acatgtaaca
     6721 ctcgtcacgg tgtctgccgt cactgttacg gtatcaactt ggcgactggt gatgcggttg
     6781 aagttggtga agcagttggt acaatcgctg cccaatctat cggggaacct ggtacacagc
     6841 ttacaatgcg taccttccac acaggtgggg ttgcctcaaa taccgatatc actcagggtc
     6901 ttcctcgtgt ccaagaaatc tttgaagccc gcaatcctaa aggggaagcg gttatcacag
     6961 aggttaaagg acaagttact gctatcgaag aagatgcatc aactcgtacc aagaaagtct
     7021 ttgttaaggg tgaaactggc gaaggtgaat atgtcgttcc atttacagct cgtatgcgtg
     7081 tcgaagttgg gggccaagta gcgcgtggtg ctgctctgac agaaggttct atccaaccaa
     7141 aacgtctcct tgcagttcgt gatgtcttgt cagttgaaac gtaccttctc ggtgaagtac
     7201 aaaaagttta ccgtagccaa ggggtagaaa tcggtgacaa acacatcgag gtaatggttc
     7261 gtcaaatgat ccgtaaagtc cgtgtcatgg atccaggtga tacagatctt ctcatgggta
     7321 ccctcatgga tatcaatgac tttacagatg ccaacaaaga tgtccttatc gcaggtggag
     7381 ttccagcgac aggtcgccca gtccttatgg gaattaccaa agcctcactt gaaacaaaca
     7441 gtttcttgtc agcggcttcc ttccaggaaa caactcgtgt ccttactgac gcagctatcc
     7501 gtggtaagaa agaccatctc cttggactta aagaaaatgt tatcatcggt aagatcatcc
     7561 cagctggtac tggtatggcc cgttaccgta accttgaacc acatgctgtc aacgaagaag
     7621 aataccttaa tcctccagta gaggaagaag gaaatgaaga aacaacagaa gtagttgtgg
     7681 atactgccgt tgaaactgtg gaagaaacag tagaataaga gaaccctcgg gttctctcat
     7741 tctctcttct gaaaactttc tccatttttc cacgaaatgt ggtaaaataa aagaaagaag
     7801 ctgacaaagg agacgagtat ggaacaaaca ttctttatca tcaaaccaga tggtgtaaaa
     7861 agaggactag tgggtgaagt gttaaagcgc atcgaacaac gtggatttac aatcgaaaaa
     7921 ttggagtttc gttcacaggt ttcagaagag ttgattgacc agcactatca ggacttggtt
     7981 ggtcagagtt tttacccacc gattcgtgaa ttcatgactt caggtccagt tcttgtgggt
     8041 gtcatttctg gtaccaaagt aatcgaaatt tggcggacca tgatgggtgc aactcgtcca
     8101 gaagaagctt taccaggcac tattcgaggt gattttgcaa aagctgctga agaaaatgag
     8161 gttatccaaa atgttgtaca tggttcagat tcagaagagt cagctaagcg agaaattgct
     8221 ctttggtttt aagagtggat tggctcaatc aattggttaa aagctcattt gaatagaaag
     8281 tatagtcaat tagtttaaga catgacgcat gatatcaaac tttttaggtt ttgatatggt
     8341 gcgttttttg attaagtgac tattagttcg tctcgctccg ttaggtgcga gacaaaacaa
     8401 ccacccgcta tgcgggtgcg cgtcgaaggt tataccaaaa aaactccaaa cgcgatacaa
     8461 taaaggtgtt caagccaatt ataaagcgaa aggagaaaaa tatggcacaa aaagcacata
     8521 gtttatcata cacaaagtgg atgtgttcta tcacattgtg ttcaccccta ggtatagacg
     8581 aacagtcatt tataatcaat atcgaagtag tttgggagaa atatttcatc gcttgtgtag
     8641 ttataaaggt gttgaaatta tcgagggtca cttaatgcct gaacatgtat agtgaattga
     8701 aataagatgt gaacatcctc tatcaggaaa gtcaaattaa tttatagaaa tattttagca
     8761 gtcaagatgt actgttatag cttcaataca ctatacatat gttagtcagt attccgccga
     8821 ggctaagtgt ttcaagtttt atggggtgtt taaaaggcaa aagtgcactc atgatgtttg
     8881 acaaacatgc caatctcaag tacaagtttg ggaatcggca tttctgggcg gaaggttatt
     8941 atgtgagcac agtagggctt aacaaagcca caattaagaa gtatagtcaa gattaaagaa
     9001 attatcgagt ggatgatttc ttcacgagta tgaaaatttg agaacgagta aagcatgata
     9061 tatagtaaaa tgaaataaga acaggacaaa attgatcagg acagtcaaat cgatttttaa
     9121 caatgtttta gaagtagagg tgtactattc cagtttgaat ctactatagc actagataaa
     9181 ttgagtgtaa aagaatatga ggctcccttt agggatagtg gtaagtaata ctaaagcctc
     9241 ttaaagaggc aagtgacgag tcaagagcaa taaggcttga acaacgtgaa agccagcgcc
     9301 taaagacgct ggctgatgat ttgggcttat agctctagga taaaccaccc gtttgacgga
     9361 ttttcatgat ttcaaattta tattcttcaa aaatctcttc aaaccacgtc agctctatct
     9421 gcaatctcaa aacagtgttt tgagcaacct gtggctagct acctagtttg ctctttgatt
     9481 tttattgagt attagtctct agtgtttgtt tagcgtctta aagagacatt tgagaagatt
     9541 agaaacagtt ctctcttttc tcctagtata atgattggta ggaagggaga gagaagatga
     9601 aatcaatgag aatcttattt ttgttagctt taattcaaat cagtttgagt agctgtttcc
     9661 tatggaagga atgcatcttg tcctttaaac aaagtacagc ttttttcatc ggaagcatgg
     9721 ttttcgtttc aggaatctgt gctggagtaa attatcttta tacccgtaag caagaagtcc
     9781 atagtgtcct agccagtaag aagtcggtga agctttttta tagtatgtta ctcttaatta
     9841 atttgttagg agctgttctt gttttgtcag ataacttgtt catcaaaaat acgctgcagc
     9901 aagaattagt tgacttttta ttgccatcct tctttttcct atttggacta gatttgctga
     9961 tttttttacc cttgaaaaaa tacgtgcgcg attttcttgc tatgctagac agaaaaaaga
    10021 cagtgttggt gactatttta gcaacacttc ttttcttaag aaatccaatg accattgtct
    10081 cacttctgat ttatattgga ctgggcttgt tttttgcagc ctatcttgtc ccaaattcgg
    10141 ttaagaagga agtttccttt tatggtcata ttttccgaga tcttgtattg gtcattgcta
    10201 cgctcatttt cttttagaga aagcctgttt tttatggatg ttatgatgat aagtttagta
    10261 ggaaaataga cacaaaagaa aagtttttgg tataataaga gtatgtacac aaaaaatgaa
    10321 gaagagttgc aagccttagg ggagcgtttg ggccatctat tagcaaagaa tgatgtttta
    10381 atcttaactg gagaactggg tgcaggtaaa acgaccttta ctaaaggact tgcaaaagga
    10441 ttacagattt ctcaaatgat taaaagtccc acctatacta tcgtgagaga gtatgaaggt
    10501 cgacttccac tttatcacct agatgtttat cgtattgaag gagatgctga ttctatcgac
    10561 ttggatgagt ttatctttgg tggtggcgtg actgttattg agtggggaaa tctcttagga
    10621 gatgccttgc cagatactta tttagaattg gaaattctaa aagaagcaga tggacgccgt
    10681 ttaaattttc aggcaaaggg tttgcgtgct gagaaattgt tagaggagct tcaatatgga
    10741 gtatgaattg ctcattaggg aagcagagcc caaagatgca gctgaattag tggccttttt
    10801 aaatcgtgtg agtttggaga cagactttac cagcctagac ggagatggta ttctcttgac
    10861 tagtgaggag atggaaatat tcctcaacaa gcaagctagt tcggacaatc agataacctt
    10921 acttgcattc ttaaatggca aaattgctgg tattgtaaat attacagctg accagcgtaa
    10981 gagagtccgt catattggag atctcttcat tgtgattgga aaaagatatt ggaataatgg
    11041 cttgggaagt ttgttgctag aagaagcgat agagtgggca caagcaagtg gcattctgcg
    11101 tcgtctccaa ctgactgtcc aaactcgtaa tcaagcagca gtccatcttt atcaaaagca
    11161 tggctttgtc attgaaggta gccaagagcg tggggcatat atagaagaag ggaaatttat
    11221 cgatgtttac ttgatgggta aactgatagg ttagtagaaa tatggttaaa aaaattattg
    11281 gaatggtgct agctttactt tctgtaactg tagtaggagt aggtgttttt gcttatacta
    11341 tttatcaaca agggacagaa accttagcta aaacctataa aaaaatcggc gaagaaacca
    11401 aggttattga agcgactgaa cctctaacca ttctgttaat gggagtggac accggaaatg
    11461 ctgaacgaac tgaaacttgg gtcggtagaa gtgatagcat gatcttgatg acagtgaatc
    11521 ctaaaacgaa aaaaacaaca atgatgagtt tagagcggga cattctgacg cgcattgaat
    11581 cagggaatgg tcaggctcat gaagcgaaac tgaactcagc atatgcagat ggtggagtag
    11641 agcttgctat agaaaccatt caaaaaatga tgaatatcca tattgatcgc tatgtaatgg
    11701 tcaatatgag agggttgcaa aaactagtgg atgcagtagg aggtattaca gtcaataata
    11761 tcctaggttt cccaatttct atcagtgacc aagaagaatt taatactatt tctatcggtg
    11821 ttggggagca acatattggg ggagaagaag ccctagtcta tgcacgaatg cgttaccaag
    11881 atcctgaggg ggattatggt cgtcaaaaac gtcaacgtga agttattcaa aaagtcatgg
    11941 aaaaagctct cagtttaaat agcgttggtc attatcaaga gattctaaaa gctttgagtg
    12001 acaatatgca gaccaatatt gatttgtctg caaaaagtat ccctaacttg ctaggctata
    12061 aagattcatt taaaaccatt gaaactcagc agttgcaggg tgaaggagag atacttcaag
    12121 gtgtttctta ccagattgtt tcaagagtac atatgttgga aatgcaaaat atactccgac
    12181 gttctttggg acaagaagaa gttactcagc ttgaaaccaa tgtggtttta tttgaagatt
    12241 tatttggcag agcacctgtt ggtgatgaag ataattaact tttgatacaa ataaaaaatc
    12301 aatcgtagga aaattcctgc gattttttca aaaaaatacg aatagatagg taggaggaaa
    12361 tatgaaagca gaaatcattg ctgttggaac agagattttg acaggacaga ttgtcaacac
    12421 caatgcccag tttttgtcgg aaaaactagc tgagattggg gtagatgtat attttcagac
    12481 agctgtagga gacaatgaag ttcgtctctt gtctttgctt gagattgcca gtcaacgtag
    12541 cagtctggtg attttgacag gcggtttggg gccaactgag gacgacctaa ccaaacaaac
    12601 cctagctaaa tttttaggga aagcattagt ctttgatcct caggctcagg agaagttgga
    12661 tatctttttt gccctgcgac cagactatgc ccgaacaccg aataacgaaa gacaagctca
    12721 aattgtagaa ggagcgattc cactgccaaa cgaaacagga ctggctgttg gaggaaaatt
    12781 agaagtagac ggagtgacct atgtcgtcct tccaggtccg ccaagtgaat tgaaacccat
    12841 ggtcttaaac caacttctac ccaagttgat gacagggagc aagctgtatt cccgagttct
    12901 tcgtttcttt gggattggcg agagccagct ggttacgatt ttggctgatt taattgataa
    12961 tcagatcgat cctaccttgg ccccttatgc caagacagga gaagtcactc tacgtctgtc
    13021 aacaaaggct agcagtcaag aagaggcgaa tcaagcgctg gatatcttgg aaaatcaaat
    13081 cttggactgc cagactttcg aaggaatttc tttacgagac ttttgctatg gttatgggga
    13141 agaaactagt ttagccagca ttgtggtaga agaactgaaa aggcaaggga aaaccatcgc
    13201 ggctgcagag agtttgacgg caggtctttt ccaagctacc gtggcgaatt tttctggagc
    13261 ttcaagtata tttaagggtg gttttgtgac ctatagcttg gaggaaaaat caaggatgtt
    13321 ggatattcct gccaagaatt tggaagaaca tggtgtggtg tctgaattta cagctcagaa
    13381 gatggctgag caggcacgaa gcaagaccca gtctgatttt ggagttagtt tgactggagt
    13441 ggcaggacca gatagcctag aaggacaccc agttgggaca gtcttcatag gcttggcgca
    13501 agagcaagaa actgaggtta tcaatgttaa tattggaggc agaagccgag cagatgtacg
    13561 tcatattgcg gttatgcatg cctttaacct agttcgcaag gctttattaa gtgactaact
    13621 tttgatataa tagtagatag gtctgaggaa cattagaatg taggagaata gaatggcgaa
    13681 aaaaccaaaa aaattagaag aaatttcaaa aaaatttggg gcagaacgtg aaaaggcctt
    13741 gaatgacgct cttaaattga ttgagaaaga ctttggtaaa ggatcaatca tgcgtttggg
    13801 tgaacgtgcg gagcaaaagg tgcaagtgat gagctcaggt tctttagctc ttgacattgc
    13861 ccttggctca ggtggttatc ctaagggacg tatcatcgaa atctatggcc cagagtcatc
    13921 tggtaagaca acggttgccc ttcatgcagt tgcacaagcg caaaaagaag gtgggattgc
    13981 tgcctttatc gatgcggaac atgcccttga tccagcttat gctgcggccc ttggtgtcaa
    14041 tattgacgaa ttgctcttgt ctcaaccaga ctcaggagag caaggtcttg aaattgcggg
    14101 aaaattgatt gactcaggtg cagttgatct tgtcgtagtc gactcagttg ctgcccttgt
    14161 tcctcgtgcg gaaattgatg gagatatcgg agatagccat gttggtttgc aggctcgtat
    14221 gatgagccag gccatgcgta aacttggcgc ctctatcaat aaaaccaaaa caattgccat
    14281 ttttatcaac caattgcgtg aaaaagttgg agtgatgttt ggaaatccag aaacaacacc
    14341 gggcggacgt gctttgaaat tctatgcttc agtccgcttg gatgttcgtg gtaatacaca
    14401 aattaaggga actggtgacc aaaaagaaac caatgtcggt aaagaaacta agattaaggt
    14461 tgtaaaaaat aaggtagctc caccgtttaa ggaagccgta gttgaaatta tgtacggaga
    14521 aggaatttct aagactggtg agcttttgaa gattgcaagc gatttggata ttatcaaaaa
    14581 agcaggggct tggtattctt acaaagatga aaaaattggg caaggttctg agaatgctaa
    14641 gaaatacttg gcggagcacc cagaaatctt tgatgaaatt gataagcaag tccgttctaa
    14701 atttggcttg attgatggag aagaagcttc agaacaagat attgaaaaca aaaaagatga
    14761 gccaaagaaa gaagaagcag tgaatgaaga agttacgctt gacctaggcg atgaacttga
    14821 aattgaaatt gaagaataag ctgttaaagt agtggagaaa tccgctactt tttcgatttt
    14881 tgattcaagt ttttagatta tatatagtag attgaaataa gatatgaaca actctattag
    14941 gaaagtcaaa ttaatttcta gaaatatttt agcagctaca gcttactatt ccaaactcaa
    15001 ccaactataa tagatcgaaa ctagaatagt acacatctac ttctaaaaca ttgttaaaaa
    15061 tcgatttgac tgtcctgatt gatttatcct gtttttattt cattttgcta tatatagttt
    15121 gctgtttctt gtcgctcctc tagaaagttg atataatagc tttatgaata aacaacgaac
    15181 agtggacctg atacatggtt cgattcttcc ctcgttctta agcttcacct tcccaatctt
    15241 gctatcaaat atttttcaac agctctataa cactgctgat gtcttgattg ttggacgatt
    15301 tcttggtcaa gaatccttgg ctgcagtagg agcgacgaca gcgatttttg acctgattgt
    15361 aggttttaca cttggtgttg gcaatggcat ggggattgtc attgctcgtt attatggggc
    15421 tcggaatttc actaaaatca aggaagcagt agcagccact tagattttag gtgctctttt
    15481 gagcattcta gttatgttgc tgggctttct tggcttgtat cctctcttgc aatacttaga
    15541 tactcctgca gaaattcttc ctcaatctta tcaatatatt tctatgattg tgacctgtgt
    15601 aggtgtcagc tttgcttata atctttttac aggcttgttg cggtctattg gtgacagtct
    15661 agcagccctg ggatttctga ttttctctga cttggttaat gtggttctag atctctattt
    15721 tattacgcaa ttgcatctgg gagttcaatc tgcaggactt gctaccatta tttcgcaagg
    15781 tttatcagcg gttctctgct tttattatat tcgtaaaagt gtgccagaac tcttgccaca
    15841 gtttaaacat ttcaaatggg acgaaagctt gtacgcggat ctcttggagc aaggtttggc
    15901 tatgggcttg atgagttcaa ttgtatctat cggcagtgta attttacagt cttctgttaa
    15961 tacctttggt gcagtgatta ttagtgccca gacggcagct cgacgcatta tggtctttgc
    16021 ccttcttcct atgaccgcta tttctgcatc aatgactacc tttgcttctc agaatcgagg
    16081 agctaagcga cctgaccgca ttgctcaagg tcttcgaatc ggtagtcgtt taagtatatc
    16141 ctgggcagtt tttgtttgta ttttcctctt ttttgccagt ccagccttgg tttccttctt
    16201 ggctagttcg acagatggtt acttgataga aaatggaagt ctctatctgc aaatcagttc
    16261 agccttttat cccattttga gcctcttgtt gatttatcgc aattgcttgc agggcttggg
    16321 gcaaaagatc cttcctctag tttctagctt tattgaacta atcggaaaaa tcgtttttgt
    16381 ggttttgatt attcattggg caggatataa gggtgttatc ctttgtgaac ctcttatctg
    16441 ggttgccatg acagttcaac tgtacttctc actattctgt catcccttga taaaagaagg
    16501 caaggcaatc ttggcaacca aagtgcaatc ctagttggat ttactgaata aaatccattt
    16561 cctctagtga gaatcgaaaa aacttgtgtt ctcctcttta gtttggtgtt gaaaatagtt
    16621 taacagactt ttgacttctt ttatatgata taataaagta tagcatttat gaaaaggaca
    16681 tatagagact gtaaaaatat acttttgaaa agctttttag tctggggtgt tattgtagat
    16741 agaatgcaga ccttgtcagt cctatttaca gtgtcaaaat agtgcgtttt gaggttctat
    16801 ctacaagcct aatcgtgact aagattgtct tctttgtaag gtagaaataa aggagtttct
    16861 ggttctggat tgtaaaaaat gagttgtttt aattgataag gagtagaata tggaaattaa
    16921 tgtgagtaaa ttaagaacag atttgcctca agtcggcgtg caaccatata ggcaagtaca
    16981 cgcacactca actgggaatc cgcattcaac cgtacagaat gaagcggatt atcactggcg
    17041 gaaagaccca gaattaggtt ttttctcgca cattgttggg aacggttgca tcatgcaggt
    17101 aggacctgtt gataatggtg cctgggacgt tgggggcggt tggaatgctg agacctatgc
    17161 agcggttgaa ctgattgaaa gccattcaac taaagaagag ttcatgacag actaccgcct
    17221 ttatatcgaa ctcttacgca atctagcaga tgaagcaggt ttgccgaaaa cgcttgatac
    17281 agggagttta gctggaatta aaacgcacga gtattgcacg aataaccaac caaacaacca
    17341 ctcagaccac gttgaccctt atccatatct tgctaaatgg ggcattagcc gtgagcagtt
    17401 taagcatgat attgagaacg gcttgacgat tgaaacaggc tggcagaaga atgacactgg
    17461 ctactggtac gtacattcag acggctctta tccaaaagac aagtttgaga aggtcaacga
    17521 cacttggtac tactttgaca gttcaggcta tatgcttgca gaccgctgga ggaagcacac
    17581 agacggcaac tggtactggt tcgacaactc aggcgaaatg gccacaggct ggaagaaaat
    17641 cgctgagaag tggtactatt tcaacgaaga aggtgccatg aagacaggct gggtcaagta
    17701 caaggacact tggtactact tagacgctaa agaaggcgcc atggtatcaa atgcctttat
    17761 ccagtcagcg gacggaacag gttggtacta cctcaaacca gacggaacac tggcagacaa
    17821 gccagaattc acagtagagc cagatggctt gattacagta aaataataat ggaatgtctt
    17881 tcaaatcaga acagcgcata ttattaggtc ttgaaaaagc ttaatagtat gcgttttctt
    17941 gtggagatat ttccttcaat gtttgctact atattaaaca aaaatcagaa agcaaactag
    18001 aaagttatgc tcaaataaaa tctaaatttg acaatgtaaa ccgagtcgga tagctttaag
    18061 tactgttttg aggttgaaga tacgattttt gataggaact catcaaatag gtttaatatc
    18121 atcaatttta gatttttaag cagcatcaat aaattgcttc cttattttgt cataattttt
    18181 ttatttaaaa aattatgaca agagtgtgct attcttttta tgagaggtgt atgaatatga
    18241 taaatgtatg tgatgttgga aaagaataaa agaacttaga atatcttcaa atcttactca
    18301 agataagatt gctgagtatt tgtctttgaa tcaaagcatg attgccaaaa tggaaaaagg
    18361 tgaaaggaat atcacgaatg gatttaagta ataaagcttc aaatcttaga aaaaagttgg
    18421 gagctgatgg tgaatcgccg atagatattt ttaaattggt acaaaagata taaaatttga
    18481 cgctggtatt ttatggactc ggaaagaata ttagcggagt ctgttataaa ggaactcagt
    18541 tcagtctcat tgcaatcaat tcagacattt attaggaagg taaagatttt ctttagcaca
    18601 tgaactgtat catctttatt atgatgaggt gaagaagagt tcagtcagtc ttatcttgat
    18661 tggtgaagga gatgaaactg aaagaaaagc ggatcagttt gcttcttatt ttttaatttt
    18721 cccatcttca ctgtatagga tggttgagga aatcagagaa aatgccaata gaactcatct
    18781 tgaagtagaa gatattataa aattgggtca gttttatggt atcagtcata aagctatgtt
    18841 atatagattg aggaatgatg gataccttga tgcagaagaa attaaaaata tggatattag
    18901 tgttatagag acagcttcaa gattaggcta tgatacaagt ttatatcgtc ctttgtcaga
    18961 aagtaaaaag gaaacggtat taggataata tatcaatctg actgaacaac ttttagaaaa
    19021 gctctattcg ggtaaaattg ttattccaca agaggtgtat gatgaaatca atatacctac
    19081 aattccccat ttaaaatcta ggatagacca gttggtaact aagggttcag ctgagattgt
    19141 gagcatagac attggaactg aagaatacgc attatataga gatttaacaa gaaatcatga
    19201 tagtaacaag attattggta agggagaagc tgcttctatt tccttagcga aaaagcataa
    19261 tgggatatta ggaagtaata acctaagaga tgttaaacca tatgtagaag aattttcttt
    19321 agaacatatg acaacaggag atatactggt tgaagcgttt aaagcgtaat ttattactga
    19381 acaagagggc aatcatatct ggaataatat gcttaaaaag agaaggaaaa ttggtgcaaa
    19441 ttcattttca gactatcttc gtggaagtat tcatcaaaat agacaaaaat aaatttggat
    19501 aaatcgaact cactattcag gaggcatatg agcaattcga aaaagaaaag tgtcaaattg
    19561 agcctatagg agtagaagtg aaatagtaag tcctgcatag tggatgagaa aaaagctgtc
    19621 cttgaagttt cccctgaact atcagtcgta tgttaaacga tatgtagggt gatgtaagag
    19681 gggatagcga gtagtttttg gttattttat caaaaacctt gtattttatc atactaaatg
    19741 ataaaatgta ataaaaatga tagaataagg aaaaaccatg aatgtcaaaa agataatgtc
    19801 gatttttcaa tccttttatg ttgatgtcag tattgaggaa ctggctttga ctttaccaat
    19861 cagttttgta aaaaggtttg agtatactca aatgactttt cataaggaat catttttatt
    19921 gattaaagaa aagagaaggg ggagtttaag ttcatttgtt actcaggctc gtactatggg
    19981 tgaaaaagcc aatatgaatg ttgttttggt gttttcaaag ttatcagaca gcgaaaaaaa
    20041 gcaattactt caagctagaa tcccttttgt cgacttcaag ggaaacctct tcttccctac
    20101 attgggacta gtactgaatg cggatgatac tgaagtccct aaggaattaa cacctagcga
    20161 acaattaaca tggattgcct ttttattgac aaaagatcaa aaagtagtag atgttgagtt
    20221 gctttcacgg gtgactggac ttccaaactc aacaatttat aggtgtttga ggacttttaa
    20281 agctttagat tggttaaaca agcaaaataa gctttacaca tatacggtgt caaagaaaga
    20341 attattctta aaatccgtgt catgtttatt taatcccatc aaaaaacgga ttttattgcc
    20401 agatggcgat ataaagcaga taaaatctgt ttctaacctt ctatatggtg gtacttatgc
    20461 tttgtcgcat tcaacttttt tagctgaaac ggatgaaaat actagctatg tcatatggca
    20521 gagaaaattc aatcagttat ccttgccact ttctcagcat gctttagaag gaaaggtgtt
    20581 agagatatgg aaatattgtc cttttatatc tgagttttgg aatgatttta aaaataatca
    20641 tgataaacaa tttgtagatc cgatttctct ttatttgacc ttaaaagatg atgatgaccc
    20701 acgtatagag gaagagagtg aagtactaga aaatatgata ttacagtatc tgggagacga
    20761 tgatgccagc taatatgaaa gctatttttc aagaaatgtt tgcggatttt aaggactatt
    20821 atgttctgat tgggggaact gctacctcta tcgtattgga ttcgcaagga tttaaaagtc
    20881 gcacaacaaa agattatgat atggtcatca ttgatgaact aaaaaataag gaattttata
    20941 ataccttgaa tcatttttta gaattgggag agtatcaagg aagtcagaaa gatgagaaag
    21001 cgcagctttt tcgatttaca acaactaaac ctgagtttcc ttctatgatt gaaccattta
    21061 gtatcttacc acaatatcca ttaaagaagg atggtcgaga aattccctta cattttgacc
    21121 aagatgctag tttatcagcc ttattattgg atgaggatta ttataatata ttggtgcatg
    21181 aaaaagagat cattcagggg tattcggtat tgagtaattg tggtctatac tcttcgaaaa
    21241 tcaaattcaa accacgtcag cttcaccttg ccgtactcaa gtacagcctg cggctagctt
    21301 cctagtttgc tctttgattt tcattgagta ttaattattt ttaaggctaa agcttggctg
    21361 gatatgaggg aacgctctgc tacaggtgct caaggtttaa gtaagttcat taaaaagcat
    21421 ttgaatgaca ttacccgttt gacagcttcc ttgctaggag atgaaaagtt atcggctata
    21481 acatcaagta gtgcggtaaa agcagacata caccgttttg tgatagaatt agagcctgtg
    21541 aagtcaacta ttcctcaaaa tgatgacatt tcattggatc aaaatgaaat ttttcaaatt
    21601 ctgaaaaatt ttctcgatgg ttaaaataat tgtagcaaga tagttatatt gaattcgtct
    21661 atctctggaa actgagcaaa actcaatttc aggagaaaat gaagtcaatc ttcccacaat
    21721 caaacgtata gtatcaaggt tttcaacacc tgatattatg cgttttttga ttttcaaaac
    21781 tttttgccca gactttgttt tttatccttt agtcacttga tttgtttcag gtggttttta
    21841 tacttttcga aaatctcttc aaacaaggtc agcttccatc tgcaacctca aaatagtatt
    21901 ttgagcagcc tgcgactggc ttcctagttt gctcttgagt attagaatag gtggtttgga
    21961 gcctcctatc ggctaggaaa tggtggcaat agtcctttgc tgaggatagg gtgtgacact
    22021 caactggttg acctagttga taggaaggga attactataa aatactcagg cttccatcat
    22081 attttttgaa acgattgtgt aattaaaatg agtctgggac aatagtctct tatctccaaa
    22141 aaaagcaacg gatttgccgt tgcttgcatt cgctcaagtt cttgaagaag aattggaaaa
    22201 cctgaaccag aacattgagg agacacccgt taaagggaag gatgagcgta aaacccaacg
    22261 tcggaaactc aagaaagtct tgcgtaaagt caaggaggat ttttcaatac gtgctgaaaa
    22321 atatgagaac tatcaggaga catttgaagg gcgtaacagt ttttccaaaa ccgatccaga
    22381 tgccactttt atgcggatga aagaagacca tatgaaaaat ggtcaactca aggctgctta
    22441 taatcttcaa atcgctacgg aaaaccaatt tgttcttcac tatgatgtct tttcaaatcc
    22501 gacagacacc aagactcttc tgccattcct tgaaacctat ccgcatgact tgaagacagt
    22561 tgccgcagat gctggatagg gaagtgaaga gaacctcctt cgtttagatg aaaaggaggt
    22621 aaaccatctg attaaatatg ccatgtttga taaggaacag aagagaggct ataaacagtc
    22681 agctagaaac ttagcaaatt ggcactatga taacaaggag gatagctaca cacatcctga
    22741 tggctggtat tatcgttttc accataccaa acatcagaaa acacagacag actttcaaca
    22801 agaaatcaag atttactaca ccgacgaacc tgaatcagcc cctcaaaagg gactgtatat
    22861 gaacaaaggc tatcaaaact tgaaagttaa agaatgtcag gcgcttttat ctccccaagg
    22921 tagacagatt ttcgctcaac gcaagattga tgtggaacct gtctttgggc agataaaggc
    22981 ttctttgggt tacaagagat gtaatctgag agggaagcgt caagtgagaa ttgacatggg
    23041 attggtactt atggtcaata atctcctaaa atacaataag agaacggctc aaaattaaaa
    23101 agctagagtt ccacaattgg aaatctctag cttttttgtg gtcgagaact attttgtccc
    23161 aggctcagaa gatgttgtgc atggataaat atatcataat tgctgtctct ctatgtaaaa
    23221 agaaggctgt atcaaaaaga tttcatatgt ctgtgcatgt atataataga cttcctgcaa
    23281 aactagaatt ctagttcatg attgataata ccagcaatca aattcattcg taatccgaag
    23341 cgtttatgat gatttcgata ggttgttgaa aacattttaa acgtttttac tttggcaaag
    23401 atgttctcaa ccttgcttct ctccttagat agtgcatggt tataggcttt atcttcagct
    23461 gttagcggct tgagtttgct ggatttacgt ggagtttgtg cttgaggata tatcttcatg
    23521 agcccttgat aaccactgtc agccaagatt ttaccagctt gtccgacttt tttgataagc
    23581 tgtttttaat acagctaaca tctcttcaaa agtcgtgcgc tgaacaccaa caagacgctt
    23641 aaatcgtgca tcagttagtt gtttacttgc ttcataatgc atagaactac tataccatat
    23701 tttgtttcgc aggaagtcta ataagttata gtccagtttt tactatactt tgatattcaa
    23761 atatgttata ctatgattat caaagtaaat g
//
LOCUS       DAVDZK010000034        23453 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVDZK010000034 DAVDZK010000000
VERSION     DAVDZK010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23453
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.035"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(54..995)
                     /locus_tag="VUX16_001602"
     CDS             complement(54..995)
                     /locus_tag="VUX16_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET8124527.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQVGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(985..2241)
                     /locus_tag="VUX16_001603"
     CDS             complement(985..2241)
                     /locus_tag="VUX16_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET8124528.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIKLHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQVSFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(2243..2905)
                     /locus_tag="VUX16_001604"
     CDS             complement(2243..2905)
                     /locus_tag="VUX16_001604"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET8124529.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIAIEDGQNLIAYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(2868..3524)
                     /locus_tag="VUX16_001605"
     CDS             complement(2868..3524)
                     /locus_tag="VUX16_001605"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET8124530.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVANPENHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(3535..4413)
                     /gene="rsgA"
                     /locus_tag="VUX16_001606"
     CDS             complement(3535..4413)
                     /gene="rsgA"
                     /locus_tag="VUX16_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET8124531.1"
                     /translation="MQGQIIKALAGFYYIESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNNLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIIYISKMDLLEDRSELDFYQQTYGDIGYDFVTSKEGLLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(4415..5287)
                     /gene="rsmA"
                     /locus_tag="VUX16_001607"
     CDS             complement(4415..5287)
                     /gene="rsmA"
                     /locus_tag="VUX16_001607"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET8124532.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGTLTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESDIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLT
                     EFASLAAALKGQGL"
     gene            complement(5418..5726)
                     /locus_tag="VUX16_001608"
     CDS             complement(5418..5726)
                     /locus_tag="VUX16_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124533.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLWVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(5719..6360)
                     /locus_tag="VUX16_001609"
     CDS             complement(5719..6360)
                     /locus_tag="VUX16_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124534.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKIIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVEALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVGLKDENRMIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(6362..8392)
                     /locus_tag="VUX16_001610"
     CDS             complement(6362..8392)
                     /locus_tag="VUX16_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET8124535.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWNQFSDRYRLSFGW
                     SSVFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPDSLREQSAYYQGLFTDYL
                     QNFSSESVEVTSRKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLSGMTIYELHGKYLLAQGG
                     VLLLGLILSSVLTGDSLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(8661..9560)
                     /locus_tag="VUX16_001611"
     CDS             complement(8661..9560)
                     /locus_tag="VUX16_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8124536.1"
                     /translation="MLIGQKIKEIRIEKGVSRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFLFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(9632..10192)
                     /gene="rnmV"
                     /locus_tag="VUX16_001612"
     CDS             complement(9632..10192)
                     /gene="rnmV"
                     /locus_tag="VUX16_001612"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET8124537.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(10192..10965)
                     /locus_tag="VUX16_001613"
     CDS             complement(10192..10965)
                     /locus_tag="VUX16_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET8124538.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQIYATIGWHPTEAGTYTEEVEAYLLDKLKHSKIVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIAYLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(11270..12100)
                     /locus_tag="VUX16_001614"
     CDS             complement(11270..12100)
                     /locus_tag="VUX16_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET8124539.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLETTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKNKQDEIKGAPLSDKEKAELLARVEAETIGVQAIAMVTVPKRPVAPNAAPKT
                     TSAPQATAGTMQDVTYQSPAGKQLPNTGSVSSAALASLGLVVATSGFALLGRKTRRRK
                     "
     gene            complement(12384..12518)
                     /gene="rpmH"
                     /locus_tag="VUX16_001615"
     CDS             complement(12384..12518)
                     /gene="rpmH"
                     /locus_tag="VUX16_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET8124540.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(12663..13877)
                     /locus_tag="VUX16_001616"
     CDS             complement(12663..13877)
                     /locus_tag="VUX16_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET8124541.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(14033..14326)
                     /locus_tag="VUX16_001617"
     CDS             complement(14033..14326)
                     /locus_tag="VUX16_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124542.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            14489..14941
                     /locus_tag="VUX16_001618"
     CDS             14489..14941
                     /locus_tag="VUX16_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET8124543.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVYSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(14976..16364)
                     /locus_tag="VUX16_001619"
     CDS             complement(14976..16364)
                     /locus_tag="VUX16_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET8124544.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            16430..17392
                     /locus_tag="VUX16_001620"
     CDS             16430..17392
                     /locus_tag="VUX16_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET8124545.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKAHLKLLIALNAGLTGQALKDYMEG"
     gene            complement(17733..18743)
                     /gene="ccpA"
                     /locus_tag="VUX16_001621"
     CDS             complement(17733..18743)
                     /gene="ccpA"
                     /locus_tag="VUX16_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET8124546.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLVKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(19167..19766)
                     /locus_tag="VUX16_001622"
     CDS             complement(19167..19766)
                     /locus_tag="VUX16_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET8124547.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLAFQADVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEIPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(19767..20864)
                     /locus_tag="VUX16_001623"
     CDS             complement(19767..20864)
                     /locus_tag="VUX16_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET8124548.1"
                     /translation="MLERLKSIHYMFWASLIFMLFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERAEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVSPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(20864..21601)
                     /locus_tag="VUX16_001624"
     CDS             complement(20864..21601)
                     /locus_tag="VUX16_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124549.1"
                     /translation="MKRWIALNKIEFLLTKRQLVYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPAVLHTDKINNWQKTLRHSPINMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVEMPLGSWVGAAILLILGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNKGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(21603..22487)
                     /locus_tag="VUX16_001625"
     CDS             complement(21603..22487)
                     /locus_tag="VUX16_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124550.1"
                     /translation="MNMIKVESLNKNIKGKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRSYLPQENVIVQKLKVKELIAFFQKIY
                     PNHLSNQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVMTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVQDLKAQGVTILYSSHYIEEVEHTADRILVLNKGGLIRDTTPLAIRSE
                     EIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWQLLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(22474..22668)
                     /locus_tag="VUX16_001626"
     CDS             complement(22474..22668)
                     /locus_tag="VUX16_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124551.1"
                     /translation="MKKAFLYLFIGLSLVVWLVEMFTGWFDQAFLHQAIRGAWGLEFM
                     IFIAFPMGKEWLKGEYHEHD"
     gene            complement(22665..22871)
                     /locus_tag="VUX16_001627"
     CDS             complement(22665..22871)
                     /locus_tag="VUX16_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124552.1"
                     /translation="MEEEEMKNKMIVAVSLVTAGVMTYLMFSGLDEGFYHFPWELFAG
                     FGMMSWLIREGLKLVSDVKKEFEK"
BASE COUNT         6758 a         5429 c         4351 g         6915 t
ORIGIN      
        1 acataaaaaa acgaacattc ttatcctaaa aaatgctcat ttttcttaaa ttatcaatct
       61 aaatctggtt tatagaagga acgattatcc atagcgaaga ttttattggt catctctcct
      121 ttatccacca aagccagagc tgttgacatc atcatcatgc ttgcatccag attgtcaatc
      181 atatggataa tctctgcctc cataatacgt ggacggactg gacttccata ttcaagcaag
      241 ccgtggtgac tgaggatgac atgacgaagc aaaacgactt cttccttggt atcatcgatg
      301 ccgagttcca taactgtctt ggtaatttcg ctatcaatga gagcgatatg tccaagaaga
      361 ttacctcgca ctgtgtactc tgtctggtct ggccccgtca actcgatgac cttagccaag
      421 tcatgcaaca taatccccgc atagagcagg ctcttattga gctgaggata aacttcgcta
      481 atagcgtctg ccaaacgcac catggtcgcc gtatgatagg ccaagcccgt ttcaaaggca
      541 tggtggttgg tcttggcagc tggataggag tagaattcct tatcatactt ggtgtagaga
      601 tttcggacaa tccgttgcca gacaggattt tcaattttga aaatcatttg cgacatgtag
      661 tcacgaattt ccttgacatc aactggtgac ttgaccttga aatcggctgg gtcattgggt
      721 tcaccaactt gaggcaggcg gagagtaatt tgattgactt gaggggtatt gttataaact
      781 tctcggcgtc ctttcatgtg gacaacctta cctgcggtaa aggcctcaat gttatgaggt
      841 tgggcatccc agagcttccc atcaatctcg ccactatcat cttggaaggt aaaggctagg
      901 tagtttttcc cagctcgagt ttgcctcagg tcagctgatt tgattaggta aaagccttca
      961 aataactcat cttttttcat gtgactaatc ttcatattct tcctcatttt cttgaaaatg
     1021 gagtagatca agcgcaggct caccttctga caactcaatg tgacggagcg tccgctcgat
     1081 agctatggta cgacggttta ataattcatc aatattgcca gaggcatgtt ggagatgttt
     1141 ttgcgccttg accagaatac caccaaactt gccaaactcg gtcttgacac tggcaagagt
     1201 cttgctgata tggtcggcac tcttttggat attaagggtc ttgaaaccaa ctgataggga
     1261 gttaagaagg gctgataggg tacttggtcc tgcaacaata atctgttctt cccgtctcaa
     1321 atcatcaaag aagaccggat tgcggacgat ttctgagtag agaccttctg tcggaacaaa
     1381 caaaactcca aaattggtcg tccgaggtgg tgctatgtac ttgttcctaa tatccctagc
     1441 aaaacgcttg acacttgcta ggagtgactt acgacagcgt tcgatttcat ccttgtcacc
     1501 tacttcatag gcttcttcta agcggtaata atctgccagt ggaaacttag agtcaattgg
     1561 taggtagacg tattcttggt cgccttgtcc gggtaacttg atggcatact ccactcgttc
     1621 actagagttt tcaaccgttg cgtattctcg ttcgtactgg gcaggtgtca tgatgtcttc
     1681 aataatttgc cccagttgca attctcccag aatccctcgc gtcttggttc cagagagaac
     1741 cttgttaaga gctccgacat cacgggcaac tgtctgcatt tctccaaggc cacgattgac
     1801 agactccagt tgtttagaaa ctgtctcaaa ggaaacctgt aagcgtgtct gcaaggtctt
     1861 ttctagtttt tcctcgaccg tctggcgcat ttgttccaaa cgttgctcat ttgattcctg
     1921 caaggcttgg agacgttggt ctgtcttgtc tctagtttgg aggagattat ctgtcatttc
     1981 ttgacggact tgggtcagac cttgatgcaa tttaatccgc acttcttgca aacggtcgct
     2041 gacagccact tccaaatctt tttggtctaa ctggctggct tgtctggctt ggtcaaagcg
     2101 gtaatccaac tggtctgaca aatgatctgc ctgatcctcc aagctcttac ttaagtgttt
     2161 ctcctgccta tcctgccttt gccaaatcag aaagagacca gctaggttgg caattaataa
     2221 tagaataagt aaactttcca tcctacctcc tgtccttgct atgcagtacg accacataac
     2281 catctgggca agttaccgac acttccctat ctatatattc gttagaagcg tacacttttt
     2341 taaagaaaaa attttcctct gtcaactcat acttggctcc aagaatagtc agctggctat
     2401 cccgaactgg cataaaggct agatagtcgt agtctgaacg aggttctagc tgactggtcc
     2461 cttctggaca ataggcaatc aagttttgcc catcctcaat cgctatctgg cgcatatagg
     2521 gtgccaactt aggattgcta ggtagaaaga cattggccaa catatggtca atacggccac
     2581 ccaaggcacc gaaaatagtg acctgagcct gaggattttg ttcaaagatg gttaagagag
     2641 ccaattccag atctgtatca tccttttctg gtcgtgcttg gacaaaatac tgggcacgtt
     2701 tttgaatcac ctgtcgctct tcttccgtca cagaatcaaa atctccgact gctagagcaa
     2761 gaggtaagtc ttcttccaat acccagagcg agcctcgatc caccccaaca aaagcatcaa
     2821 aatctgtccg ataatgaccg cggtttccgc ctgcaaaaac tgcaacccta gtccagttgt
     2881 tttctgagag tttgtactcg ctcattgact tctcccttaa agacatagga acctgctaca
     2941 aaaacagtcg caccagcttc tttggcttga gcaatagttt ggtcatcaat cccaccatcc
     3001 acttcgattt caaagttcaa acctttttcc tcacgaagag caaccaactc acgaacctta
     3061 tccatggttt ctggcagaaa ggcttgccca ccaaaacctg gattaaccgt catgactaaa
     3121 acttggtcaa ctagatgaag gacgtgcttg atggcttcaa ctggtgtgcc aggattgata
     3181 acgactgaag gcttaactcc gagtgaacga attttttgga gggcgccatg aatatgaggt
     3241 gttgcttcta catggatact gatgatgtct gcacctgcac gcgcaaagtc ttccagatga
     3301 ttctctggat tagctaccat caagtggcag tcaaagacca tcttgctatg aggtcgaaga
     3361 ctctcgacca cacctgcacc aaaactgatt tgcggtacaa aatgactgtc catgatatcg
     3421 atatgggcat attctgcccc agttgcttct aggcgtttga tttcacgttc aaagttggca
     3481 taatctgctg ctagaattga cggagcaatc ttgtattgag acataggttt ctccttattt
     3541 tggaattttt ttgctgactt ttttataggt ttctctgcga ttttcaattt cgctgaggaa
     3601 ttgcaggtag ttgtcaaaac ggaagggcgc aatggtacct tcttcaactg ctggcttgac
     3661 agcacaggac ggctcatggg tatgggtaca agtacggaac ttacagtctc gactgacagt
     3721 agcaatctct ggaaaggcct gattgaggtc ttcagccgtt gacacttcat aatccagtga
     3781 tgaaaagcct ggtgtgtctg cgattttacc cccattgagg ttgtaaaaac taactgctcg
     3841 agtggtatgg cgcccgcgac ccagactgtc tgagatttct cccgtttcaa gattaaggtc
     3901 tggtgcgatt ttattgagaa gggttgattt tccaacacct gtctgcccca taaagactgt
     3961 aaccttgcct gttaacaaag gaaggagtcc ctctttactg gtcacaaagt catagccaat
     4021 gtcaccatag gtctgctggt aaaaatccaa ttctgaccga tcttccagca aatccatttt
     4081 agaaatataa atgataggat ggatgccctt atgctccaaa agaaccaaga aacgatccag
     4141 caaattgctg ttaaaatcag gttccttgac agacatgatc accacagctt ggtcaatatt
     4201 gacaataggc ggacggacca gattgttttt ccgttcatga atcttgagga tatagccttc
     4261 tgaattttcc tcggcagaga aatctaccca gtccccaacg taaggagtat ggcctttttt
     4321 acggaaattc ccacgcgcgc gtgtttgata gacctggcca tcactctcta tatagtagaa
     4381 gcctgccaag gccttaataa tttgtccctg catcttagag cccttgccct ttaagcgcgg
     4441 ctgctagact ggcaaattct gtcaagctga gtgcttctcc acgcacactt ggtgacaagc
     4501 ctgcttggtc caaggcctta gtcagcttgt ccttgacttc ttcagtcttg ccaaagtaac
     4561 ctgtcaggtt attccataag gtcttgcggc gatgagtgaa actagccttg gaaaccttaa
     4621 agaagaagtt ctcgtcttcc actgctacag ctggctctgg acgacgcacc attttcaaga
     4681 tggctgaatc cacatttggc gctggcacaa agaccgtacg aggcacgata aaggcaacct
     4741 tggctgtcat gtaatactgc acggcgatag acaagctacc gtaagccttg gtgttaggct
     4801 gggctgaaat gcggtccgct acttctttct gcatcatgac cacaaactca caaaaaggaa
     4861 tgtcactctc aatcaagtgc atgagaatag gcgtcgtgat gtagtaaggc aaattagcca
     4921 ctaccttgat tggcaggtca ggatttttaa aattctggat atgttgcgcc aaatcaacct
     4981 tgagaatatc ttcgttaact acggtcacat tatcaaaatc acgcagggta tctgccaaaa
     5041 ttggcaccaa acggtggtca atctcaaaag ccatgacttg ggctgcacgc tcagccaaaa
     5101 attctgtcaa ggtaccaata cctggcccga tttcgatgac attgacctga tcatcaattt
     5161 cagccgtatc cacaattttt tgaaggatat tggtatccgt caaaaaattt tgcccaaagg
     5221 actttttaaa ggtaaaaccg tgacgctcca gcactgcctt ggtcacgcta taatctgcaa
     5281 ttctcatcta ttctcttttc tattatctgt tactactatt gtaacacatt ccccttgtat
     5341 tttgggaatg aaaatcatac caaaaaacta tctttcctca tgaagaaaga tagtcttgga
     5401 aatctttaaa agtggcctta gcagttctct cgaaacatgc gttcaaaaaa atcagcttct
     5461 tgataacttc gattttcggg tagggtcaaa tccacatcct cctccacatc atccactgtc
     5521 agttcaaccg tctgaggtaa atttttcaaa cgataatgct tttgcctttg cccttcaata
     5581 ctagcaaaat caagcaaata gccatgcact cggatttgaa cccaaaggag atgattggtc
     5641 atattttcca tgatgaggat atcttctaaa ccacctctgg cactaggata atcagatacc
     5701 ctgcgaatac ggattttttc acacatgagc aagtttcctc atatcaatga tttcatcagc
     5761 cttattccag actaggggat tatgggtcgc aatgatgatc attcgatttt catctttcaa
     5821 gcccaccaag agattcataa cctcctctga attttcagga tcaagagctg ctgttggttc
     5881 atctgccaaa atcaagggtg gatttttcaa aatagtctta gcaagggcaa ctcgttgggc
     5941 ctctccccca gataaagtat aaattttttg ttctagatcc aaatacccta gattaacttt
     6001 ttctaaagcc tccacttgcc tttccaaacg ttctactttt gaaatctttt gaccaacaaa
     6061 gcccaaatcc aaattttctt tgattgattg gttttctaaa aggccaaaat tttgaaagag
     6121 atagcccatc tgatctcgaa aatactcacg agtgggaatg atttttaaat ctttcccctg
     6181 atagagaacc cttcctccat ctatcttctc tagctttccc aagatattca gcagcgtcgt
     6241 ctttccgctt ccactcttcc cgattaaggc atagaccttg cccttctcca gtttgagatt
     6301 caaaccagag aaaatcgctc ggtcattaaa tttcttttcc aatccttgaa tatcaatcat
     6361 cttattttcc tttcaatact gccatgctac cagcttcttc ctttttatcc tgccttacta
     6421 aaatcaagag ggcgttaaga gtaaataaag ctacaactaa agcgctgatc aagctatctc
     6481 ctgtcaaaac actagataga attaggccaa gcaagagaac tcctccttgc gccagtaagt
     6541 acttgccatg aagctcataa attgtcatac cagaaagacg tttaatcata agctcccgtc
     6601 taaactgctc aaaatagaga agattcatgg aatcaaataa caagatagcc gtagacaggg
     6661 tcaaaatcgt cccaataagg agagagtaaa actccacccg tttgtcattt agtaccttgg
     6721 caaaaaatag ctggcttttt accaagtaag aaaccttgtg atacagacct tgctctttta
     6781 gagctgtgat gctgtctcca tatcgatcta gtttcaaggc actattagcc gtagttcccc
     6841 acaacatccc tgcaacaggt cttgttccag tcgcttgcgg cgttagaact acaataatcg
     6901 gatcttttag gtactggcgt gttgtcttgt acccatcatt atagaggaaa cgttcctgtc
     6961 ctgtttctgt aaaagctagc cttacctgtg ggaagtagtg tttccgactc gtcacttcta
     7021 cactttcaga tgaaaagttt tgcaggtaat ctgtaaacaa tccttggtag taggcagact
     7081 gctctcgcaa gctatcaggc aagatcagcc caaactctcc ctcagacaag ttttgcatct
     7141 tgtccataaa ctctgaagaa acggtaatct tttcttctat cagatagcgt ggtgagacat
     7201 agataacatt ccctgacggt gtgtagtcac tgagacgatt gccatctagg tccacttctg
     7261 ctccatctga gaaattgtca acattgctca taatataaaa agagtctgta ttggctaacc
     7321 gttcttcagt aaatgtctgc cactcacgat tatccttacg cgttccttct tcatcggcaa
     7381 atacactaga ccaaccaaag gatagacggt aacggtctga gaactggttc catttattgc
     7441 tagctctctc catttcctgc atttcacggt agtggggtag gagagctgtc gcactcgatc
     7501 cgaccaccaa tacagctaag agttgcccca ccatcatcaa tgtcatcata cgtttgagag
     7561 ggagtttccc tttcaataga tccaccagac tattttcctg taaaccaagt agatagacga
     7621 cacttagtaa ggtagaaatc cctgccaagg tcaatccata aagtagaaga gcaatgatga
     7681 ccagttgcac cgttgccata aacaaggcac cttgatacca gagaatcccc aatcccaaaa
     7741 gactggatac cagcactgag cagataagct gtctcacatc ttctaacact ggtctgagag
     7801 caactccaaa caagctctca ccagctatta agcgaatccc tgcctgacga agggatttga
     7861 tccgataaat aagggtcaga ctcataaagg tcagcagaaa aatagctaaa ctcagtagca
     7921 ccataggggt ggccgccaat agtaagacta tcgaaaatgg atcttctcca ttcgaaacaa
     7981 agccttgata accaagctct ttcaaggtgg tctgtaagct cactccatcc aaacttcctg
     8041 atacaatcaa gtaagaccct aataaatcac tcgtttctgc actctccttg gaggaaatgg
     8101 tcagaccttc tggaagcttt ccctcaccat aagtggcata ggtaaagcgt gtttctccag
     8161 cttcatttgg ctcaacaatc cgacgggcga tgagactatt atgctctacc gccaagtgac
     8221 tcaaagcctc tgtcacctct tcgcgactag ctactggttg atttatcatc attcctgtca
     8281 catcaacaga aggatagtta ccaaataaaa tctcttctcg atggtcaacg gaagttatca
     8341 ccatataaag cgataccaat accattgaaa tcaaaataaa taaacgtttc atcatttcct
     8401 ccaaaaagtt acttggtcac ttagtgagaa ggtgaccaca gtcactgcca tgttaagaag
     8461 tttattaagt tttttctact agcaacatct tcaaatatat tatatccgtt ttttcaagaa
     8521 ctatcaaggg catcaatgtc cttaaaatct aaccatttcg tgtcattttt agcttatatc
     8581 taaaaaaaca gccctaaaga cgaactttag aactgttttg atgcgagaac aaggacattt
     8641 ttgtcactga ttcactatgt ttataaatat tttttgacat cctcttgcca ttcctctgtc
     8701 aatttcttta ctagaaattc atctccaatt agctgcgcaa atgttttaga agactgataa
     8761 aatgattcag ctaaactaaa atctctttct tctcttaatg cttgcttcca caaaaacaga
     8821 aatacaagag gtttcttttg ataatcttga gttttatcca taatttcttg taaacacgat
     8881 agataatcat taaaacaatc agttactcct accttttcaa gacaacacat tcctgaaata
     8941 agagtatctc taattataaa gaagttttct aatttagtta cctttttctg ttccaaaaga
     9001 aagagcatta gcttttcgat ttgatttata aatttggcaa gatcttttct aatgagcatt
     9061 tgataaaaaa acaaacgaat caacaacata tcatttgttg aataaacttc tttttctatg
     9121 atctgaggca tatgttcctc aagtattaac tctgcatatt caggccttct agttctagaa
     9181 gtatccaaac acgcctgcaa tacttcacac gctaattgtt cttctttagg aagattatca
     9241 aagtatgttt tataaatctc ttccaaacac gcttccttct tatcgtactc ctcttcttta
     9301 ccatagattg gttcacgtaa aatctggtat ttcaattcta aataagcaga aggaagagct
     9361 gaaaaatccg gcataaggct ataaactgga actcctagcc ggcgagcaat atagtctaac
     9421 ttgggcaaac tcggttgcga agctccactt tcaattcgcg acagttgacg aactgtcagt
     9481 tcttgctcat ctccacaaaa atctggacga ctaactcctt tttctatccg aatctcttta
     9541 attttttgac caattaacat cagacgcctc ctcttctacc tgcttcgaaa aatactgtga
     9601 aacttaaaaa attgtaacgg ctacatcttt cctactcata agatttcata gcttcttcca
     9661 cttctgccaa agtaacccca aacaactcta ggcgtttgag gagttgcttg ccgttagaat
     9721 agccgattcg gagagtctct ccgagatatt ctctacgctt acggctgtct gcccctgcta
     9781 gaaaaccaag gcgaatcaaa tcgctacgac taatgtcaaa ctgactctca tgttcaaatt
     9841 gttctgtcac ctgagctaga gccgttttca ggtcttcata gctggcatgc tcaattccca
     9901 gagaacgccc cttggtcttg gacttgggaa cagcttcatc tcgcttgaga aaggcatgct
     9961 gaactgttgg aatggccgtc ataatcatgc gccgaatccg ctccccatta aaatctgggt
    10021 ctgtaaagac aatgactcca tgacgttggt gtagacgctg aattcgctct atatcctgat
    10081 cattgatggc agaacctcgt gtctcatagg tctccacatc gaaataacgc ttgagattga
    10141 ccgtatcatc gcgaccttca accacgataa cttgagaaat tttctctttc attacttgct
    10201 gtccaatcca aaaattcgtt ctgcatttgc agtcgttgct accgccagct cttctgtcgt
    10261 cataccacgc aagtaagcga taaagtcgac cacatagcga gtataggctg ttttattttc
    10321 acgaccacgc ttgggtacag gtgctaagta aggcgcatct gtttccacca acatcttgtc
    10381 caaaggtaac tctttagctg cttcttggag gtcagttgcc ttcttgaaag tcaccactcc
    10441 tgagaaggaa atggtcatac caagatccac aaacttctct gcccactcaa gcgtccctga
    10501 aaatgaatgc atgataccac cacgaggacc aacgccctca ctcttgataa tctcataggt
    10561 atcttccagc gcatcacggg tatggacaac aaaaggcaaa tccaagtcct tagatagctg
    10621 aatctgacgg cgaaaaacct gctcctgcac ctctttgggc gctgtcatcc aatggtagtc
    10681 taagccaatt tcacctaaag ccacaatctt ggaatgtttt aacttatcca acaagtaagc
    10741 ctcaacttcc tctgtataag taccagcttc tgtaggatgc caaccaatag tcgcatagat
    10801 ctgctcatac tcatctacca actccaaggc atgctcaatc gtcggtttat caaaaccaac
    10861 aatattcatc tgtgtcacac ccatctcagc agccaaggca atttcttctg cctcacgacc
    10921 tgcaaattct tctacattca agtgtgtatg tgtatcaaaa atcatctctt ctaacctcgt
    10981 tttctatctt ctattatacc aaaaaagagg aggggcacct aatttttcgg tttcccctcc
    11041 tctcttcaat aaagagctat tctgctatct tttctatccg atattgccca tctcctattc
    11101 cacagttaga gacagaagag attggctaca ttgatagaat attcctattc agctaaagta
    11161 tatgattatc ttgggttctc acttttctca cccatcacta ggattgatga cttctcaaaa
    11221 tcccccttat aatttaactt taagtagaga atagaatttt ctagctgttc tattttctac
    11281 gtctagtctt tcttcctagc aaagcaaaac cacttgttgc caccactaga ccaagactag
    11341 caagtgctgc acttgatact gaacctgtgt taggtaattg tttgccagca ggtgactggt
    11401 aggtaacatc ttgcattgtt cctgcagttg cttgcggtgc acttgttgtc ttaggagcag
    11461 cattaggagc cactggtctc ttaggaactg taaccatggc aatggcttgc actccaatcg
    11521 tttctgcttc cactcttgct aaaagttctg ctttttcttt atcagaaagc ggtgcgcctt
    11581 tgatttcatc ctgcttgttc ttggctgctt tttcaatggc atttttagct gattcttttt
    11641 cagtagctaa ttgcttagaa gcttgtgatt gagctgagtt ttgtgaacct gtgtgagctg
    11701 atccacccgc ctggctacca ccgccttcat tcgcattagc atctgagctt ccagtattgc
    11761 ctcccttatc tccacctggt gtagtttcta gcttatactc tggtgtagct tcttgagtta
    11821 cagattcacc tttcgcagat tgttgaactg tatcttttcc tagaatcgtc actactgaac
    11881 catctgggaa tgtgattgtt gctgtaccat ctccagctac attgattgta gctccgtcta
    11941 atgctgaacc atttgcttgt aaaatagcaa ccttaacttt ttcttcatct gttaaatgag
    12001 ttatatcttt tacatctact ctttgagcag gtgctttaac agttgatttt tcagcagtcg
    12061 gtttagtact atcttgtgct tttggatctt gtgctaccaa ttgatttcct ggaattgtaa
    12121 tagctgaacc atctttaaag acgattgtcg ctgtgccatc tccagctact tcaactttat
    12181 agtaaaataa aataataaca ggacaaatcg atcaggacag tcaaatcgat ttctaacaat
    12241 gttttagaaa cagaggtgta ctattctagt ttcaatctac tataacatcg cttccgaatc
    12301 catttgcatc tactgaactt ttttacaaaa ataaaaatca gtagactcga gttcctactg
    12361 atttttgata gaattcgttt ggattatgca gccaaaactt tgcgtccttt acgacgacga
    12421 gctgccaata cgcgacgacc atttttagtt gacatacggt tacggaatcc gtgtttgcgc
    12481 gcacgacgaa gtttacttgg ttgataagta cgtttcacga tgaatacctc ctcatagatt
    12541 ttgtattcgt ttagccggct ataaagtgat cagttactaa acatacttta ctattctatc
    12601 tgattctttc acttttgtca atagctctag gcaaatgttt ccagcttttt cgaatgcaag
    12661 ccctatctac gatactgttt caagaaacga gtcatctttt cttggatttg ggctaactca
    12721 tcaacacgag gaaggtaaac gatacggaag tggtctggtt cctgccagtt aaagcctcga
    12781 ccatgaacca agagaacctt ttcctgcttc aagaaatcaa ggacaaactg ctcatcatca
    12841 tcgatacggt acatattgcg gtcgattttt gggaagatat agagccccgc cttgggttta
    12901 acggcagaca aacctggaat atcttgaatg gcattataga tgaaatttct ttgctcgtag
    12961 attcgtccac caggaagaag caattcatcg actgattggt gaccccccaa ggaagtttgt
    13021 acgacttgtt gggccaaaac gttagagcaa aggcgcatat tggacagcat attgagccct
    13081 tcgatatagc ccttaacatg agtcttaggg ccagacaaga ccatccaacc cacacggaaa
    13141 cctgctatgc ggtgggattt tgacagacca ttcatgctga cacagaagac atctggtgcc
    13201 aagctcgcca caggcgtatg cacatgtccg tccattacca tgcggtcata gatttcatcc
    13261 gcaaagataa tcaaatcgtt ttgacgggca atctcaataa tctccagcaa gagttcctta
    13321 ggataaaggg ctccagttgg gttatttgga ttgataagga cgattgcctt ggtattggaa
    13381 gtgatttttg acttgatatc gtcaatatct gggtaccatt caacagcttc atcacagata
    13441 tagtgaacgg catttcctcc agctaggctg acagccgccg tccatagagg atagtctggc
    13501 attggcacta agacctcatc cccattgtcc aaaagcccct gcatggacat gacaatcaac
    13561 tcactgacac catttccaag gtaaatatca tcaatatcta cgtttgggaa tttcttcagc
    13621 tggcaatact gcatgatggc cttacgggct gagaaaatcc ctttggagtc agaatagcct
    13681 tcactatcac gcgcattcat aatcaagtca tgaatgacct cgtctggcgc tgtaaagcca
    13741 aattctgctg gatttcctgt attcagacgt aaaatctttt ctccattcgc tcgcatccgc
    13801 atggcttctt ccaatacagg accacggata tcataagcaa catgctctaa cttactagac
    13861 ttgttatatt ctttcatctt gtttcctcaa ttcatcagga tagtaacatt ataccactag
    13921 aaagagaatg cgacaagttt actgaaatat gttactagtt tcgtatagaa gaaaaacctt
    13981 gctaaaggcg aggttaagaa cgtagagata gcaggtattt tgcaaagaca catcacatac
    14041 caaaagataa acctagaaaa agcaagccta gaaaggagtc ataaagaaga ttaaacatga
    14101 ggaaaagccc ccatatcatc aagtaatccc aacgcccact tcgttttgca actagaaata
    14161 agattagatg gtagagtaca tgaaagacta aaaatccaat aaaacttgga taaagaagcg
    14221 gtaccagact ctctaattga cagatcatga tcacttctac caagactgaa actaggataa
    14281 ttccataata aaggaaattt gatttttgaa aagagttttt catcattctc ccttccttca
    14341 cttctttcct gctatccttt ctttttattt tatcatatat ttatatagag tttaagccct
    14401 aatattcttt tgaaaaatac tttttttgct ttacttctat agtgaaaagg tttacaatta
    14461 tagtaagaaa atttcaggag gtttcattat ggcacaacgt taccaaaata tcatggtcgc
    14521 aatcgatggt tctaaggaag cggacttggc ttttgtcaag ggagtttatt ctgctctacg
    14581 aaacgacgct aaactcacca tcgcacatgt cattgacaca cgcgctctcc aaagcgtatc
    14641 cacctttgat gctgaagttt acgaagaact ccaagtcgac gctgaaagtc tgatgaaaga
    14701 gtacgaaaaa cgtgctaaag atgctggggt agcagatgtt catatcgtca ttgaaatggg
    14761 aaatccaaag accctgctag cacgtactat tccagatgcc gaggaagtgg acctcatcct
    14821 cgttggcgca actggtctca acgcctttga acgcctcttg gtcggctctt catctgaata
    14881 catactccgc catgctaagg tcgatttgct ggttgtgaga gaacaagaaa aaaccttata
    14941 atcacaaaga aaaggagccc ctagctcctt tttgtttacg atttatttct ctctttatgg
    15001 cgttcgtaag ccttgagctg gcgctgcagt tcctttttaa tagcaggttc tggagcatat
    15061 ttttcttccc aattatctgg ttttaagatt ttatgggtca ctggatcaaa atgagccttg
    15121 ccatctggaa aaattttccc catattagcc tgatggacaa tatcaaaaat acgttctggg
    15181 tcgaccccca tcaagacaaa actgccgtag gtgaagtaaa gcgtgtcaat caaggcatcc
    15241 acttgcccta tcaaatcttg ctgagcaggt gtcttcttgg ctactttacc tgctgcctta
    15301 tcaagggcct gatgaagttg cgatacagct tgaccaaaat cttcttcaga aggactggct
    15361 gctcgaacaa actccaccaa ttcttctatt ttaaaaccag ccctatgggt tgcaccctct
    15421 aaatcccaag ctcgaggttc ttcttgggtt cgttcatcca tcatgtggtg gaaggtcttg
    15481 accttattga aatgatagtc acggctgaca aagacttttt ctgaagacaa aacaccaaaa
    15541 tgttccaagg ccttgtggat cccatcttgt tgattgctag tggtaatgtg cttggcagct
    15601 tccttgacac tgctactacc atttcccata gcgaccgaca taccgacgcc agccagcatt
    15661 tcaaggtcat tatctgagtc accaaaagcc atgacttggt tgaggtcaaa gccatattct
    15721 ttcccaactc ggcgaatgcc ttctaattta gaatttccct gattgatgac atccgatgca
    15781 aaaggattgc tacgtgtcaa tttcaagtct tcaaaatcag ctgccgcctt ctcagattct
    15841 tctggtgtca tcagcatcaa aacttggtag ataggctgat tcatcaggtg aagcaggtcc
    15901 tcttcctttt ggggaacaac cttgctgacc atgcgattaa aagactgact caccgtccga
    15961 gttaaaacag agggaacgaa gcgactaatt cgttgggaaa aagaacccag accaaaggac
    16021 atgattttag aacccaacat ggcatccttg gtccctaggg caatctccgt gccctctttt
    16081 ttagcatagc taattagatg gcgcaaatgt aacttggaaa tagggctcgt gaacaagact
    16141 ctgtctttac taaagatata ctggccatta taggttaccg caaaatccag atccaaatcg
    16201 tccatcaatt ccttaacaaa aaaaggtcct cgccctgtcg ctacgccaac tagtacccct
    16261 tgttctttga caatcttaat cgcgtcctta gtggatttca aaacactctt gcgattgttg
    16321 accaaggttc catcgatatc aaaaaaaaca gctttgactt ccatcctatt ccaatctccc
    16381 cttttgtgat acaatgatta taccacattt cagaaagagt gagtaaatca tgcctaagaa
    16441 aatccttgtt ttacatacgg gtggaactat ttccatgcag gccgatgctt ctggcgctgt
    16501 tgtgacgagt tcagataatc ccatgaacca tgtgtccaac ccacttgaag gaatccaagt
    16561 ccacgccttg gactttttta accttccaag tccccatatc aaacccaaac atatgctggt
    16621 cctctaccag aaaattaaag aggaagcaga taactacgat ggagtggtga tcacacacgg
    16681 aaccgatact ttagaggaaa cagcctattt ccttgatacc atggaagttc cccatatgcc
    16741 tatcgttcta acaggagcca tgcgtagctc caatgagctc ggtagtgatg gtgtttataa
    16801 ttacctaagt gctttacgag tggccagcga tgacagggct gctgacaaag gagttttggt
    16861 cgttatgaac gatgaaatcc acgctgccaa gtatgtcacc aaaacacata cgactaatgt
    16921 cagcaccttc cagactccaa cacatggccc cctcggtctc atcatgaaac aggaaatcct
    16981 ctacttcaaa acagctgaac ctcgtgttcg ctttgacctt gatcacatac aaggtttagt
    17041 ccctatcatc tcggcttatg ctggtatgac agatgagctg attgatatgc tggatttaga
    17101 acacttggac ggtttgatta tccaagcctt cggagctggt aatattccca aagaaacggc
    17161 tcaaaaatta gaaagccttc tgcaaaaagg aatcccagtc gctctggtat cacgatgctt
    17221 taacggtatt gccgagcctg tttatgccta ccagggtggg ggcgtacagt tgcaaaaagc
    17281 aggcgttttc tttgttaaag aactcaatgc ccaaaaagcc cacttgaaac tcctcatcgc
    17341 cctcaatgcc ggactaacag gacaggcttt gaaagactat atggaaggct aatactcttc
    17401 gaaaatctct gcaaaccacg tcacgtcgcc ttaccgtatg tatggttact gacttcgtca
    17461 gttctatcta caacctcaaa aacatgtttt gagctgactt cgtcagtttc atctacaacc
    17521 tcaaaaacat gttttgagct gacttcgtca gttctatctg caacctcaaa gcagtgcttt
    17581 tagctgactt cgtcagttct atctacaacc tcaaaacagt gtgttgcgca gcctttaacc
    17641 agccgcctag tccgctctat ggtattcatt aagtcaacat ctcttgttta agagcacaaa
    17701 atcaggaaat cttctcgatt ccctgatttt ttctatttac gttttcgtgt tgagctacgt
    17761 tctgtcaaac catgaggtaa gagaacttca cgttcttcca actcttcctt atgcataatc
    17821 ttggtcaaca tacgcatact aatggcacca aggtcataaa gaggttgggc aatcgttgtc
    17881 aagtttggac gggtaaagcg tgagatttgt gaatcatcac tagtaataat ttcaaaatct
    17941 tctggcacag aaacaccctt atcagccaaa ccgttcaaga ctcctgctgc caactcatca
    18001 cctgtcacaa ctgctgcagt tgcatttgat gaaatcaaac gctctgctaa ggcgtaacca
    18061 tcatcatagc tatatttaga ttcaaatacc aaaccctcac tataagtgat tcctgctttt
    18121 ttcaaggttt ccttgtagcc aactaaacga accttaccat tgatgtcatc cactagcgga
    18181 ccgctaacga aagcaatacg ctcattttct ttaacaaggt aactcactgc atcaattgtt
    18241 gcttgcttat agtcaatatt gacacttggc aactggtgct ccacatcgac agttcctgcg
    18301 agaacaatcg gagtacgtga acgcgaaaat tctgagcgaa ttttatctgt caagtgataa
    18361 cccatataga taatgccatc tacctgcttt gaaaagaggg tattgacaac agaaacttct
    18421 ttctcgttat cttcatcgct attagctagg acaatattgt acttgtacat ttctgcaata
    18481 tcatcaatcc ccttagccaa actcgaaaaa taaccattgg taatatttgg aatcacgaca
    18541 ccgacagtgg ttgtcttttt acttgcaaga ccacgcgcaa ctgcatttgg acgataatcc
    18601 aaacgatcaa ttacctctag cactttttta cgggtattct cttttacatt tttattgcca
    18661 ttgaccacac ggctgaccgt cgccatggaa acacctgctt cacgagcgac atcataaatg
    18721 gttactgtat catctgcatt cattcctttt cctgtccttt ctatctcaca cattctttta
    18781 caagtagagg tgctgattga agctctatat ctacttacaa aagtgaagat gtgaaaattt
    18841 cgttttcata tttctactta ttccattcta tcactaattg taaacacttt caagtgtttt
    18901 ttgaagattg attgaaaaaa tttcatagaa aacctaggtt tagctccttg ctaccacctt
    18961 agactaaaca aaaaggagga aactaagccc tcctaaagtt atagtaaaat gaaataagaa
    19021 caggataaat cgatcaggac agtcaaatcg atttctaaca atgttttaga agtagaggtg
    19081 tactattcta gtttcaatct actataggta ttgttccatt cactaccgtc aattttagca
    19141 catagtcttc ataaaatatt atatcatcat aaccaaccag attcttttgc gatattagct
    19201 gcctctgttc gattaccagc atccagtttt gaaagaatat tggtgacata gtttcgaata
    19261 gttccgtttg agaggtaaag ctgatctgcg atttcttggt tggataagcc ccgggcgatt
    19321 ccctttaaga cagcaatctc ttgttctgtc aacggattgg gacgggtcat caccacttcc
    19381 atcaattcag gcgaatactc cttgcgtcct tcgaggacgg tgtgcaaggt ttgcatgagg
    19441 tctgcaatgc ttcgttcctt taatacataa gcatctactc cagccttgac cgcacgttca
    19501 aaataccctg ggcgcttgaa ggtcgtcact acaaccacct ttgtttcgag cttttctgct
    19561 cgtatccact ccaagacttc gagtcctgtc ttaacaggaa tttctacgtc aaggatggcg
    19621 atatctacag actccttttc taatagttga attgcttctt gaccattctt ggcttgtaag
    19681 acagactcta catctgcttg aaaggcaagc aactggcaca tggcatctcg caacatactt
    19741 tgatcttctg cgactaatac tttcatctac tttctctcct tataaggtag tcgaacttgc
    19801 acttccgttg gatgtttctg actgattaca cttacttctc ctgaaaatgg agaaacacga
    19861 tctcggactg tatggagctc atctcctttt agaaaagcaa agccgcagcc atcatcactt
    19921 actgttaaaa tgagttcttt ctctgcccgt tctaatttca ggtaggcctt cgacgctttg
    19981 gcatgtttga taatattggt caccaactca agcaaaatca tggaagccgt tgactccaat
    20041 tcttgagtaa gactagcagt atctagttgg ttatccgttt ccacctcaat tccagcaatt
    20101 tctaacatct ttttcacagt ctctagttcg gatgtcaaag ttctagactt aagattttcc
    20161 acaatggttc gcacttcatt catggaatcc ttactgatct ggtgaatttc ttttaattcc
    20221 ttttccacct gtggataagc ctccatctga aataactgca aggctaaatc tgtcttgaca
    20281 ctcaacatag caaaggtatg tcccaagcta tcatgcaaat cctgaccgat acgactgcgt
    20341 tcattttcag caagcaatag atttatctgg gcattttgct tagcctgagc ttctttcaaa
    20401 tcctccacaa tacgaatccg aaccaagcca aaagtcatta aatcgacaaa agcaagaatt
    20461 acaagtagat agaatagaaa ctcaacttcg attctctgaa aaatcaacag ttggcccaca
    20521 acaaggactt gagcaagaag aaaagtccag acatgtaaag actttaaacc acctacgctg
    20581 aaatgataac ttaagagatt ggataggaaa aagaaaaacc agatataatt aacagcaaca
    20641 aaggcagtat tcccaactac ataagtcagc atgaggcccc aatatagcca agataggcgc
    20701 tggctcttag ttgttaaaac acccaaatac gccactacaa atagaatatc aatcaataaa
    20761 tgccaggcag aaagccaccc agtcactaca ggtaggatgg gaaaaagcat aaaaatcaaa
    20821 ctggcccaaa acatatagtg tatgcttttc agtctttcaa gcattaagca ttctccttat
    20881 gaccttgaag gtaaatagtc aaaccaaata aaactgctga aaaaacaagt agataaactg
    20941 tggctgatag attgatgcca cccttgttta agaaggtctt gagtaactcc atcaactgat
    21001 aggtcgggag acacttaccg actgcttgca tccagtctgg aaataaagag ataggcatcc
    21061 agagcccacc taaaacagcc aagccaaggt aaagaagatt gcccacgaca gacatcagct
    21121 gactagttgg taagagcgtc aaggtcaagc caagcgctac aaaagcaata cttcccaaaa
    21181 taagcaaaat cgcagcccca acccagcttc ctagaggcat ctctacacct cttacaaaat
    21241 gcccaactga gaaaaccacc aagattgaaa ccaaataatc aaccagcata cttgttatct
    21301 ttgatagata atattctacc atatttatag gactatgacg taatgttttc tgccagttgt
    21361 tgattttatc tgtatgtaaa acagctggga atgaaaagat agctgtcgac atcatggaaa
    21421 aagccgtcat ggagatgagg taatcacgca taaaattagc tggtccacca ggtgtgtcct
    21481 ggtacatgcc tgaaaagaat aaatagaagg ctgtcggcat ccctacggat aatagataat
    21541 agactaattg tcgtttggtc aatagaaatt ctatcttgtt tagtgcgatc catcgtttca
    21601 tcttagtcat ctcccttttg tgtttcttca aagattgtat ccaacaagct acgattattg
    21661 acttcaattt cttgaatcct acatcctgct tgcactaaca gttgccaaaa agcatccgct
    21721 tcacgtgtaa ctacttgcaa agcatcttgt ttttgtgacc agttttcaac caagttagac
    21781 tgctcaatga cttccttgta agctagagga aggataaagt gcttttcaat ctcctcactg
    21841 cgtatggcta gaggtgttgt atcgcgaatc aaccctccct tattcaagac caagattcgg
    21901 tccgctgtat gctctacctc ttcgatgtaa tgggacgaat agagaatggt aactccctgc
    21961 gcttttagat cctgaacaat ctcccaaaaa cgttggcggg ttgaggtatc catggccgca
    22021 gttggctcat ctaaaaagac aagttttggt cggccaatca aggtcatgac aaaagagaaa
    22081 agacgctttt gcccacctga caatttttct gcaaattgct ctttttgttg ctggtcaaac
    22141 tgcaatagtt gatcgatttc ctgattactc aagtgatttg gataaatttt ttgaaagaaa
    22201 gcaatcaact cttttacctt tagtttctga acgattacat tctcttgagg gagataggat
    22261 ctagtgtagt ctaacttaga gctcgtcact ggcaagcctt ggatggatac ttgaccgctt
    22321 gtgaccagtt tatctccaag cagacagtcc aagagtgtgg tcttcccagc accattgggc
    22381 ccaatcaagg cgacgcattc accttcagct acctcaaagg aaatatcctt caaaatagcc
    22441 ttgcccttga tgtttttatt taggctttct accttaatca tgttcatgat attctccttt
    22501 cagccactcc tttcccatag gaaaggcgat aaaaatcata aattctagtc cccaggcacc
    22561 gcgaatggct tggtgaagga aggcttgatc aaaccaacct gtaaacattt ctaccaacca
    22621 tactactagt gatagtccaa taaaaagata gagaaacgct tttttcattt ttcaaactcc
    22681 tttttcacat ctgagactaa tttcaaacct tctcggataa gccaggacat cattccaaat
    22741 cctgcaaata gctcccaagg aaaatgataa aatccttcat ccaatcctga aaacatgaga
    22801 taagtcatga ctcctgcggt tactagactc actgcgacaa tcattttatt tttcatctct
    22861 tcttcctcca tttcatactt caattataga cttttgaagt ttgcggagct agatgcttct
    22921 gtcactagga aatatgacaa ctgtcataaa agattctgtt caaaacaagc aagatacact
    22981 atacaataaa acacaatcag aaaaatctaa ggcaacttcc tcaaaagaga tatcaaaccc
    23041 aattcacacc ataatgtaaa ctaatactta tttaaaatca aaaagagtag aaatttttat
    23101 cagacaaaca catatatagt gtattgaatc tataacagta ggccttaaat actaaaatat
    23161 ttctataaat taatttaact ttcctgatag agctgttcat atcttatttc aattctctaa
    23221 attatacgtt gaacaaaacc cttctatttc tttcttaaaa atttataaga gttataaaat
    23281 ctgttaaatt tcaatgtgta tacctaaact acggtattta ttgaaaaaac tggagacaaa
    23341 aagtatacgt tgccaaaatg aattactgaa aatcaaaaaa gagagaacca aactgattcc
    23401 ctcttaatgt atataatatc tagttttaaa aatacacact cacatatctc tgt
//
LOCUS       DAVDZK010000035        22180 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVDZK010000035 DAVDZK010000000
VERSION     DAVDZK010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22180
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.036"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(268..1248)
                     /gene="dusB"
                     /locus_tag="VUX16_001628"
     CDS             complement(268..1248)
                     /gene="dusB"
                     /locus_tag="VUX16_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET8124553.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLID
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1235..2107)
                     /gene="hslO"
                     /locus_tag="VUX16_001629"
     CDS             complement(1235..2107)
                     /gene="hslO"
                     /locus_tag="VUX16_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET8124554.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2272..3699
                     /locus_tag="VUX16_001630"
     CDS             2272..3699
                     /locus_tag="VUX16_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET8124555.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMVENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3858..5366
                     /gene="glpK"
                     /locus_tag="VUX16_001631"
     CDS             3858..5366
                     /gene="glpK"
                     /locus_tag="VUX16_001631"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET8124556.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGATFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5408..7234
                     /gene="glpO"
                     /locus_tag="VUX16_001632"
     CDS             5408..7234
                     /gene="glpO"
                     /locus_tag="VUX16_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET8124557.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSPFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKACLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEVFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVKAALAQNDLAELKN"
     gene            7304..8008
                     /locus_tag="VUX16_001633"
     CDS             7304..8008
                     /locus_tag="VUX16_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET8124558.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSAGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEVEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8305..8508
                     /locus_tag="VUX16_001634"
     CDS             8305..8508
                     /locus_tag="VUX16_001634"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124559.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8595..9202)
                     /locus_tag="VUX16_001635"
                     /pseudo
     CDS             complement(8595..9202)
                     /locus_tag="VUX16_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10289..11565
                     /gene="ltrA"
                     /locus_tag="VUX16_001636"
                     /pseudo
     CDS             10289..11565
                     /gene="ltrA"
                     /locus_tag="VUX16_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            12021..12731
                     /locus_tag="VUX16_001637"
     CDS             12021..12731
                     /locus_tag="VUX16_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET8124560.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLLYQQI
                     YWKFFQIRFGFLPLYLFL"
     gene            12677..13198
                     /locus_tag="VUX16_001638"
     CDS             12677..13198
                     /locus_tag="VUX16_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET8124561.1"
                     /translation="MEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTVYSIGIIISG
                     LIAFRLSEKFLAAKWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVP
                     ESVFLQETVEENHLVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMI
                     EAILIYIRRDYFK"
     gene            13512..13643
                     /locus_tag="VUX16_001639"
     CDS             13512..13643
                     /locus_tag="VUX16_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET8124562.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13664..15214
                     /gene="dltA"
                     /locus_tag="VUX16_001640"
     CDS             13664..15214
                     /gene="dltA"
                     /locus_tag="VUX16_001640"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET8124563.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15211..16455
                     /gene="dltB"
                     /locus_tag="VUX16_001641"
     CDS             15211..16455
                     /gene="dltB"
                     /locus_tag="VUX16_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET8124564.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVIT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16469..16708
                     /gene="dltC"
                     /locus_tag="VUX16_001642"
     CDS             16469..16708
                     /gene="dltC"
                     /locus_tag="VUX16_001642"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET8124565.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16701..17969
                     /gene="dltD"
                     /locus_tag="VUX16_001643"
     CDS             16701..17969
                     /gene="dltD"
                     /locus_tag="VUX16_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET8124566.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYEPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIGDVVKADAEKNTSNNDLGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            18124..18564
                     /gene="adcR"
                     /locus_tag="VUX16_001644"
     CDS             18124..18564
                     /gene="adcR"
                     /locus_tag="VUX16_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET8124567.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQQFLTALVGEIK"
     gene            18564..19268
                     /locus_tag="VUX16_001645"
     CDS             18564..19268
                     /locus_tag="VUX16_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET8124568.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVTISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENDQEVGHA"
     gene            19261..20067
                     /locus_tag="VUX16_001646"
     CDS             19261..20067
                     /locus_tag="VUX16_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET8124569.1"
                     /translation="MLSLLSYDFMQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFLLISLVRRFIK"
     gene            20077..21582
                     /gene="adcA"
                     /locus_tag="VUX16_001647"
     CDS             20077..21582
                     /gene="adcA"
                     /locus_tag="VUX16_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET8124570.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLFQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYVGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKFTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
BASE COUNT         6469 a         4224 c         4913 g         6574 t
ORIGIN      
        1 gctatagagt caatgccaat ggtgaatggg taaactaaac ctaatataac tagttaatac
       61 tgacttcctg taagaactct ttaaagtatt ccctacaaat accatatcct ttcagtagat
      121 aatataccct tgtaggaagt ttagattaaa aaataactct gtaatctcta gccggattta
      181 tagcgctaga gactacggag tttttttgat gaggaaagaa tggcggcatt caagaggctc
      241 tttaagagag ttacgggttt taaactatta agccttctcc aattgcaaga gggcttcaat
      301 ctctgccagg gtgctagctt gcgaaatggc tccacggagt ttggcagcgc cagatgttcc
      361 acggagatag tgaggagcga ggccgcggaa ttcacgaact gcgacgtttt ctcctttgag
      421 gtcaatcaat cgtttcaagt gttcgtaggc gatcttcatc ttgtcttcaa aggtcaaatc
      481 aggtaggatt tctcctgttt caaagtaatg gttgatttgg ttgaagaggt aaggatttcc
      541 catggcagct cggccaatca tgactgcgtc agcaccaact tcttcgatgc gttgcttggc
      601 ttcttggaca gtacggatat caccgttggc gatgaatgga atcttggtta gagcttgggc
      661 aaccttgtaa agggtctcaa ggtctgcgtg gccagtatac atttgttcac gggtacggcc
      721 atgcatggcg agggcagaaa cacctgcagc ttcagcagcg agagcatttt ctactgcaag
      781 agatgggtcc gcccagccgg tacgcatttt gacagtaagt gggatatcaa ggacagactg
      841 gaccttgttg atgatagagt agatcttgtc aggatccttg agccacatag caccagcttc
      901 gttcttcacg attttgttga cagggcagcc catgttgata tcgacgatat cggtcttggt
      961 gttttcttgg atgaattctg ctgcgcgtgc taggctgtct tcatcgctac caaaaagttg
     1021 gatagagaca gggttttcgc cctcatcgat atgaagcatg tgcagggttt tttcgttgtt
     1081 gtattggatt cccttgtcag agaccatttc cattacaacg agtccagctc cgagctcttt
     1141 tgcgatggta cgaaaggctg agttggtcac gccagccata ggcgctaaaa cggtacgatt
     1201 gggaatctca acattgccaa tcataaaagg tgtattaaga tttgtcacga atgagttcct
     1261 ccaggtcctt ttcatcaaag ttgtaagtag tttggcagaa ttgacaagtg atttctaccc
     1321 cgtggtcttc ctctttcatt tcctgtaagt ctgagcttgg aaggctggca agagcgttca
     1381 taaagcgttc atggctacag tcacattgga aacggatttc ttcttcagaa agacgcttgt
     1441 aggcttcgtc cccgtagata gccttgagga gggcttcgat atggtcgtcg ctttcgagaa
     1501 gagtagagat agctggcatt tcttggatgc gtttttcaaa gcgagcaatc tcttctttct
     1561 tggctcctgg caagacttga actaggaaac cacctgcaat cttgaccttg tcttcctcgt
     1621 ccaaaaggac attgaggccg accgctgaag gcgtttgttg gctttcagta aggtaaaagg
     1681 caaggtcttc accgatttct ccagagatga ggggagttat agagttgtaa ggatttccag
     1741 taccgtagtc tgtgataacg aggaattgac catttccaac aaaaggtccg actaggactt
     1801 caccagtcgc agtctttttg atgtcaacac caggattttg aacgtagcct ttgacgttcc
     1861 ccttggtatc agcgacggtg ataatagcac ctagagagct agatcccaac accttaactg
     1921 taagtttggt atttcctttt tcattggctg cgagaatctg gctggcgata agagttcgac
     1981 caagcgctac agttgagcta gcttgggttt gatgtttttc ttgagcagtg cggacggttt
     2041 cagtgctatc aaggacaaaa gcacgaaagg ctccgctttc tgatatagtt ttaataattt
     2101 tatccatagc tactatttta gcataaaaat gcccaaaggg ggagccgtgt gtttactgat
     2161 tttcaggata atggaccagg aaatcagcat gaaaataaaa agagaaacag attattttag
     2221 catttgtaag atttatgcta tgcttaaggt agaaaatgaa aggggtaaca aatgtattta
     2281 ggagatttga tggagaaagc cgagtgtggt caattttcaa tcctttcctt tctattacaa
     2341 gagtctcaga cgaccgtcaa ggctgtaatg gaagaaacag gattttcaaa agcaacccta
     2401 accaaatatg tcaccctgct caatgacaag gctttggata gtggcttaga gctggctatt
     2461 cactcagaag atgaaaatct gcgtctgtct atcggtgcag ctaccaaggg gagagatatt
     2521 cggagcttgt ttttggagag tgctgttaaa taccagattt tggtttatct tctctaccac
     2581 caacagtttt tagcccatca gctggctcaa gaattggtga ttagcgaggc tacgcttggt
     2641 cgtcacttgg ctggtttaaa tcagattttg tcagaatttg atttatccat ccaaaatgga
     2701 cgttggcgag gtccagagca tcagattcgc tatttctatt tctgtctttt ccgaaaggtc
     2761 tggtcgagtc aggaatggga aggtcacatg cagaaaccag agagaaaaca ggagattgcc
     2821 aatttagagg aaatctgcgg tgcaagtttg tctgtggggc agaaattgga cttggttctc
     2881 tgggctcaca tcagtcaaca acgtcttcgg gtcaatgctt gtcagtttca agtcatagaa
     2941 gagaaaatgc gagggtattt tgacaatatc ttttatcttc gtttgctgag aaaggttccg
     3001 tccttttttg ctgggcaaca tattccacta ggagttgagg atggtgagat gatgatattc
     3061 ttctcttttc tcctatctca tcgcattctt cctcttcata ctatggagta tattcttggt
     3121 tttggagggc agttggcaga tttactgacg caattgattc aagaaatgaa gaaggaggaa
     3181 ctattggggg attatacaga ggaccatgtc acctatgaac tcagtcagct ttgtgctcaa
     3241 gtctatctct ataagggcta tattttacag gatcgctaca agtaccagtt agagaatcgt
     3301 catccatatt tactgatgga acatgatttt aaagagacag cagaggagat ttttcatgct
     3361 ctacctactt ttcaacaggg gacagattta gataagaaga ttctctggga atggctccag
     3421 ttaatcgaat atatggttga aaacggtggc cagcatatgc ggattggtct ggatttgaca
     3481 tctggttttc ttgtcttttc aaggatggca gccattttga aacggtattt ggaatacaat
     3541 cgttttatta ccattgaagc ctatgaccct agtaggcatt atgatttgct ggttaccaat
     3601 aaccctattc ataagaagga acagacacca gtctattatt taaaaaatga cttggatatg
     3661 gaagatttgg cagggattcg tcagttatta ttcacttaaa aggcttggtt aatccaggtc
     3721 ttttttgtga aattcacaca atctcctcac atttttttaa aaattaaaaa aagttgataa
     3781 acaagaaagc gctttatttt gtatactagt aagtgtaaag aggaaacacc tcaagatctt
     3841 tatcaggagg acagtacatg tcacaagaaa aatacatcat ggctattgac cagggaacta
     3901 caagttctcg tgccatcatt ttcaacaaaa aaggggaaaa ggttagctcg agtcaaaaag
     3961 agtttaccca gattttccct caggcaggtt gggttgagca caatgccaat gaaatttgga
     4021 actctgttca gtcagttatt gcgggtgctt tcattgaaag tggtgtcaag ccaaatcaaa
     4081 tcgaggcaat cgggattacc aaccaacgtg aaacaacggt tgtctgggat aagaaaacag
     4141 gacttcctat ctacaatgct atcgtttggc agtcacgcca gacagcacct ttggctgagc
     4201 aactaaaaag ccaaggttat gtggaaaaat tccatgaaaa gactggtttg attattgatg
     4261 cttacttctc tgctaccaag gttcgttgga ttttggatca tgtagaaggt gctcaagagc
     4321 gagcagaaaa aggggaattg ctctttggta ctatcgatac ttggttggtt tggaaattga
     4381 ctgacggtgc ggctcacgtg actgactact caaatgcagc tcgtaccatg ctttataaca
     4441 ttaaagaact caaatgggat gatgagattt tggaaatcct taacattccg aaggctatac
     4501 ttccagaagt tcgttctaac tccgaaatct acggcaagac agctccattc catttctacg
     4561 gtggagaggt gccaatctca ggtatggctg gggaccaaca agcagccctc tttggacagt
     4621 tggcttttga accaggtatg gttaagaata cttatggaac aggctctttc atcatcatga
     4681 atactgggga agagatgcag ttgtctgaaa acaacctctt gacaaccatt ggttacggaa
     4741 tcaacggtaa ggtttattat gccttggaag gttctatctt catcgcagga agtgctattc
     4801 agtggcttcg tgacggtctt cgcatggttg aaaattcacc agaatctgaa aaatacgctc
     4861 gtgattctca caacaacgat gaagtttatg tcgttccagc ctttacaggt ctaggcgctc
     4921 catactggaa ccaaaatgct cgtggttccg tctttggttt gactcgtgga acaagcaaag
     4981 aagactttat caaggcgact ttgcaatcta ttgcttatca agtgcgtgat atcatcgaca
     5041 ccatgcaagt ggatactcag accgccattc aagtactgaa ggtggatggt ggtgcagcca
     5101 tgaacaactt cctcatgcag ttccaggcgg atattttagg cattgacatt gcacgtgcta
     5161 aaaacctgga aacaacagct ctaggagcga ccttcctagc aggtttgtca gtagggtact
     5221 ggaaagactt ggacgagttg aaactcttga acgagacagg agaactcttt gagccatcta
     5281 tgaacgaatc tcgcaaggaa caactctaca agggctggaa gaaggctgtg aaagcaactc
     5341 aagtctttgc ggaagtagac gactaatact ggcagaataa agcgatttat ttagaaagtg
     5401 tgtaaatatg gaattttcaa agaaaacacg tgaattgtca attaaaaaaa tgcaggaacg
     5461 taccctggac ctcttgatta tcggtggagg aatcacaggg gctggtgtag ccttgcaggc
     5521 ggcagctagc ggtcttgaga ctggtttgat tgaaatgcaa gactttgcag aaggaacatc
     5581 tagtcgttca acaaaattgg ttcacggagg acttcgttac ctcaaacaat ttgacgtaga
     5641 ggtggtctca gatacggttt ctgaacgtgc agtggttcaa caaatcgctc cacacattcc
     5701 aaaaccagac ccaatgctct taccagttta cgatgaagat ggagcaacct ttagcccctt
     5761 ccgtcttaaa gtagccatgg acttgtacga ccttttagca ggtgtgagca acacaccaac
     5821 tgcgaacaag gttttgagca agaaagaagt cttggaacgc cagccaaact tgaagaagga
     5881 aggcttggta ggaggtggag tgtatcttga cttccgtaac aacgatgcgc gtctcgtgat
     5941 tgaaaacatc aaacgtgcca accaagacgg tgccctcatt gccaaccacg tgaaggcaga
     6001 aggcttcctc tttgacgaaa gtggcaagat tacaggtgtt gtagctcgtg atctcttgac
     6061 agaccaagta tttgaaatca aggcctgtct ggttattaat acaacaggtc cttggagtga
     6121 taaagtacgt aatttgtcta ataagggaac gcaattctca caaatgcgcc caactaaggg
     6181 agttcacttg gtagtggatt caagtaaaat caaggtttca cagccagttt acttcgacac
     6241 aggtttgggt gacggtcgta tggtctttgt tctcccacgt gaaaacaaga cttactttgg
     6301 tacaactgat acagactaca caggtgattt ggagcatcca aaagtaactc aagaagatgt
     6361 agattatcta cttggcattg tcaacaaccg ctttccagaa tccaacatca ccattgatga
     6421 tatcgaaagc agctgggcag gtcttcgtcc attgattgca gggaacagtg cctctgacta
     6481 taatggtgga aataacggta ccatcagtga tgaaagcttt gacaacttga ttgcgactgt
     6541 tgaatcttat ctctccaaag aaaaaacacg tgaagatgtt gagtctgctg tcagcaagct
     6601 tgaaagtagc acatctgaga aacatttgga tccatctgca gtttctcgtg ggtctagctt
     6661 ggaccgtgat gacaatggtc tcttgactct tgctggtggt aaaatcacag actaccgtaa
     6721 gatggctgaa ggagctatgg agcgcgtggt tgacatcctc aaagcagaat ttgaccgtag
     6781 ctttaaattg atcaattcta aaacttaccc tgtttcaggt ggagaattga acccagcaaa
     6841 tgtggattca gaaatcgaag tctttgcgca acttggagtt tcacgtggtt tggatagcaa
     6901 ggaagctcac tatctggcaa atctttacgg ttcaaatgca ccgaaagtct ttgcacttgc
     6961 tcacagcttg gaacaagcgc caggactcag cttggcagat actttgtccc ttcactatgc
     7021 aatgcgcaac gagttggctc ttagcccagt tgacttcctt cttcgtcgta ccaaccatat
     7081 gctctttatg cgtgatagct tggatagcat cgttgagcca gttttggatg aaatgggacg
     7141 attctatgac tggacagaag aagaaaaagc aacttaccgt gctgatgtaa aagcagctct
     7201 tgctcaaaac gatttagcag aattaaaaaa ttaagaaaaa ataaaagagg tggagggcag
     7261 cattccttgt cgcccgtccc ttctttttaa tggagacaga aagatgatga atgaattatt
     7321 tggagaattt ctagggactt taatcctgat tcttctagga aatggtgttg ttgcaggtgt
     7381 ggttcttcca aaaaccaaga gcaacagtgc aggttggatt gtgattacta tgggttgggg
     7441 gattgcagtt gcggttgcag tctttgtatc tggcaagctc agtccagctc atttaaatcc
     7501 agctgtgaca gttggtgtag ctttaaaagg tgacttgcct tgggcttccg ttttgcctta
     7561 tatcttagcc cagttcgcag gggctatgct gggtcagatt ttggtttggt tgcaattcaa
     7621 accgcattat gaggtagaag aaaatgcagg caatatcctg gcaaccttca gtactggacc
     7681 agccatcaag gatactgtat caaacttgat tagcgaaatc cttggaacct ttgttttggt
     7741 gttgacaatc tttgctttgg gtctttacga ttttcaggca ggtatcggaa cctttgcagt
     7801 gggaactttg attgtcggta tcggtctatc actaggtggg acaacaggtt atgccttgaa
     7861 cccagctcgt gaccttggac ctcgtatcat gcacagcatc ttgccaattc caaacaaggg
     7921 agacggagac tggtcttacg cttggattcc tgttgtaggc cctgttatcg gagcagcctt
     7981 ggcagtgctt gtattctcac ttttctagtt tatactcttc gaaaatcaaa ttcaaaccac
     8041 gtcagcgtcg ccttaccgta ctcaagtaca gcttgcggct agcttcctag tttgctcttt
     8101 gattttcatt gagtattaga aaacaattat gttgatagag cttgggcaag agcccaattt
     8161 cagcaaaaaa tgaagtaaat cttctcataa taaaacgcat catatcaagc acgaaaattc
     8221 cacgaggtca actacagtca gaaagctgaa caacaagcca aaacgcccaa aaaaggcggc
     8281 aaaaagcaag cacctgcaag caacgtgccg aaatggtcaa atcctgatta tgtcaacgaa
     8341 ttagacccaa aaatcgttga tatgctagta gaatttcaca agtcacaagg cactttggaa
     8401 actcccgagg cgcaagcaga aatcgcccaa aaacgtgaag aaatcgagca aaggagagct
     8461 gagcttgagg ataaaaaaca agagcttttg aaccgcttga acaaatagag tttcgcaagt
     8521 attatgctta caaattactt gagcaattaa ctaaaatata aaccctgcct ttatatctag
     8581 gcagggttta tattttagaa attcacgtag gttgttacgg tttttacata cccagtatag
     8641 tttgagtttc tatagtattc agtgataaac ttccattttc tttgagcaac atggatataa
     8701 gtacttgtta tgtagtatgg atatgggctt tgtgaatcca agtaagactg ataagcttgt
     8761 ataccaaaat atgctccacc aattattgca ccccatggac ccccaataaa gcacctatcc
     8821 taccaatcat ataactgatt ccagcaccag tcatgaagtt agcgaatgtg ttagcttgtt
     8881 tattcccatg tattgtgttg acgtaattcc aaacattagg atcgtatgat ctaaaagata
     8941 tatttaggtc gatttcattc ttttgataag ccatataaaa tgccccattg atatagacgc
     9001 cgtcagcacg tcgttcaata gtgtctacac ttccatctgg attgacaacc tcaagaactt
     9061 catcgcttaa aatatttact tgcgtatctc cgaaccgcac tgatgagcca ttctcaaact
     9121 gagcctcacc agatacaact ttagagtttg ccgataagct atcatcagca aaaacaacaa
     9181 gcgacgggga aatgctagac atacagaaaa cagacataac tagcaaacac atgcatttaa
     9241 acatcttaga cataacggaa actcctttgt atttttgatt tttttcaact tttattatac
     9301 aataaaacca aataaaaaga aagcggtaac aatatgctta atgcgaaaat tttttatata
     9361 tttttatgtt tgatcgttat cgaaactaca ggcttgttgt tgttgaaaag aggtctcgaa
     9421 atgggttatt tagacacaga agctattatc ctcgcagttt tttcatttgc tttttacaac
     9481 ctatgttcat tcgcttgggt ctgctctaca ataaaaaaca ataaaaaata aatagacgta
     9541 ttttcaaaaa aaaaaatgca tatttatctt agcaaaacga cgatttaaat cgtcgttttt
     9601 ttgtagtacg acgggcatgt cgtatatctg aggtgtaagt cctcggtggg cacctgctac
     9661 cggtgaaccc aatagcgatt cccaagcctg actatcgtga ggtagcaggg agaggaaggg
     9721 atagcgaaat cgtggctcta cgaacaggaa cgtgatagta aggcgtatat agcggataag
     9781 gaggcttcaa actctaaagt ccaaaaagga agtcgtaacc tatatgtgta aatcacgaga
     9841 gtaattgaat tcggactaag gtttgtgtga aaaagataaa tctttctaga gtctaaagac
     9901 tctgcgtcag atttcctatt ttcactgtaa ccttttaacg tcctcatatc ttgtataaac
     9961 gaggaaagat gtacgactta tcccgtgagg tttcatgagc gctgaaagcg tagtaacaac
    10021 gaatcatgag aagtcagccg agcccatagt agtgaggaaa cttccgtaat ggaagtggag
    10081 cgaaggggtg aatactcaaa cagtctgggg agagactgtt tgaggtctgt cgctagaaag
    10141 agaaaacgac agatcgaagt aatcctactt cacttgtgtc tgtaaaatga gtggtctgat
    10201 agaactggac tttgacacgt aatgactaga tgaaggttca ccaatataag atgtccctca
    10261 ggcaccaaaa caagaaagga atacgcacat gtcaaaactg ctagataaga tattatcacg
    10321 cgaaaatatg ctggaagcct acaatcaagt aaaatccaat aaaggctcag ctgggattga
    10381 tggaatgact atcgaagaga tggataatta tctcagacaa aactggcgct tgactaagga
    10441 actgataaaa cagagaaaat ataagcctca accagttctt aaagttgaga tacctaaacc
    10501 agacggaggc atccgtcaac taggaattcc aacagttatg gatagaatga ttcaacaggc
    10561 cattgtccaa gtcatgaacc ccatttgtga accccatttc tcagatacga gttatggttt
    10621 cagaccaaat aggtcatgtg aaaaagccat catgaagctc ttagaatact taaataacgg
    10681 ctatgagtgg atagtggata tagacctaga gaaatttttc gatacagttc ctcaagatag
    10741 attgatgtcc ttagtacata acattatcga agacggagat acggaatcct tgattcgtaa
    10801 gtatcttcat tcaggtgtta tcattaatgg tcaacgttat aaaacactag ttggtacacc
    10861 acagggagga aatttatctc ctctcttatc caatatcatg cttaatgaat tggacaagga
    10921 attagaaaag aggggacttc gatttgtgcg ctacgcagat gattgtgtga tacggtcgga
    10981 agcgaggcag ccgctaagcg tgtgatgtat tcagtcagtc gttttattga gaaacggcta
    11041 ggtttgaaag taaacatgac caagactaag attaccagac caagagagtt gaaatatcta
    11101 ggttttgggt tctggaaatc atcagatggt tggaaaagtc gtccacatca agatagtgtt
    11161 cggagattta agcttaaatt gaagaaacta acacagagga aatggagtat agacctaaca
    11221 agacgtattg agcaactgaa tttgtctatt cgaggatgga taaactattt ctcattggga
    11281 aatatgaaaa gtatagtcgc cagcatagat gagcgcttgc gtactcgcct acgagtgatt
    11341 atctggaagc aatggaagaa gaaatcgaga cgattatggg gattgcttaa gttaggagtt
    11401 cctaaatgga tagcagataa ggtatctggc tggggcgacc attatcaatt agtagctcag
    11461 aagtcggtac ttaaacgtgc tatatcaaaa ccagtcctgg aaaaacgtgg actggtttcg
    11521 tgtttggatt attaccttga acgacatgcg ttaaaagtta gttgaaccgc cgtatgccga
    11581 acggcacgta cggtggtgtg agaggggcta gagattatcc cctactcgat taactcccct
    11641 gaaatttatt ttaattatgc aaatttcacg tatttttgat gctgagacga cgatcctggg
    11701 aacttttcag atattttttt gactatctaa atctatcatt agaaaagctt agagcgccaa
    11761 aggatttgag cgtttttctg atttttaaga ctttttccag tctctttttc gattgaagat
    11821 gtaattattc tactaactaa ctaacttctt agtactagcc aacaacgata atcataattc
    11881 ctcctaaaat taggaataat aaaggcaata gtttttgttt tttcatgtaa aaaacctcac
    11941 ttttgttttc tgctatttta tgctaaaata ttaaaaatca aatttaattc caaagtttgt
    12001 aactaaaggg ggagcgctac atgtctaatt catttgtcaa gttgttagtc tctcaattat
    12061 ttgcaaattt agcagatatt ttctttagag taacaatcat tgctaacata tacattattt
    12121 caaaatcagt aattgccaca tcactagttc ctatcttaat aggaatatcc tcttttgttg
    12181 cgagtctttt agttccgttg gttactaaaa ggttagcgct aaatagggtt ttatctttat
    12241 ctcaatttgg aaagactata ttattggcga tactggtagg aatgtttacc gtaatgcaat
    12301 ccgtagcgcc tttggtgacc tatctatttg ttgttgcaat ttccatacta gatggttttg
    12361 cagcacccgt ttcctatgct attgtgccac gctatgcgac cgatttgggt aaggctaatt
    12421 cagccttatc aatgactggt gaagctgttc aattgatagg ttggggatta ggtggactct
    12481 tgtttgcaac aattggtctg ttacctacca cgtttatcat tttagtcttg tatatcattt
    12541 ctagctttct gatgttattt cttcctaacg ctgaagtgga ggtgttagag tcagaaacta
    12601 atcttgaaat tttgctcaaa ggttggaagt tagttgctag aaatcctaga ttaagacttt
    12661 tgtatcagca aatttattgg aaattttttc aaatacgatt tgggtttctt ccattatact
    12721 tgtttttgta acggagttat taaataaaac ggaaagttac tggggatatt ctaatacagt
    12781 atactctatt ggtattataa ttagtggctt aattgctttt aggctatctg aaaagttcct
    12841 tgctgctaaa tgggaaagta ttctttttcc tcttgtagct atggcaatag tgacactgac
    12901 tattctatat tttccaaacg cacagatgtt tttattattt tcagctttag ttggtatgtt
    12961 atcgcaacta aaagaagttc ctgaaagtgt atttcttcag gaaacagtag aggaaaatca
    13021 tttagttaat gtctattccg ttcttgaagt gatttctaca ttagcatttt cagtatttgt
    13081 tttgctaatg agctatatta ctgagagttt tggtattagc atcagttttt ggctatcagc
    13141 catttgtctg atgatagaag ctattttaat ttatatcaga cgagattatt ttaaatgaga
    13201 gagtggttaa aaagtcttta aaaatcagaa aagcgcatag tatcaggtgt tgaaaaaact
    13261 tgatattgtg tgttttatta tgggaagatt tacttcattg tctcctgaaa tggagttttg
    13321 aagcaggatc actctatttg aaaatataca tagaaaaacc gcataatcct taaaataagc
    13381 tgaaatctat tggaaacata cggtaaacaa ttgaaaagat actatataaa gtggtacaat
    13441 ggtagaaaaa taagctagta agaatcactc ttattttagc gaaaaattac agaaatgaat
    13501 ggtttttctt gatgaaacag agaaaagaat tgtacctctt tcttggtcgg acagccttgt
    13561 attttcttat ctttctaggg ctgctttact tctttagcta tcttggtcag ggtcaaggaa
    13621 gctttatcta taatgaattt taacttgaag gagaatccct attgtgtcaa ataaaccaat
    13681 agcagatatg attgaaacca ttgagcattt tgctcagaca cagcctagct atcctgtcta
    13741 taatgttttg gggcaggaac acacttatgg cgatttaaag gctgattcgg atagtttggc
    13801 tgcagtcatt gaccaactag gcttgcctga aaagtctcct gtggttgttt ttggtggcca
    13861 agaatatgaa atgttggcaa cctttgtagc gctgactaag tcaggtcatg cctacattcc
    13921 aattgatagc cattcggcct tggagcgagt ttcagctatt ttagaagtag cagagccaag
    13981 cttgattatt gccatttcag cctttccctt ggagcaggtt tctacaccaa tgataaatct
    14041 agctcaggtt caagaagcct ttgcccaagg gaacaactat gaaatcacgc atccagtcaa
    14101 gggagatgat aattactaca ttatctttac ttctggtacg actggtaagc ctaagggagt
    14161 gcagatttca catgataatc tcctcagctt tacaaactgg atgattacgg ataaggaatt
    14221 tgcgacaccg agtcgtccgc aaatgctggc acagccacct tattcttttg acttgtctgt
    14281 catgtattgg gcaccgacct tggcacttgg tggtacgctt ttcactcttc cttcagtcat
    14341 cactcaggac tttaagcaac tctttgcggc tatcttttca ttgccaatcg ctatctggac
    14401 atcaacacca tcctttgcag atatggccat gttgtctgaa tacttcaaca gtgaaaaaat
    14461 gcctggaatc acgcatttct actttgatgg tgaagaattg acggtcaaaa cagctcaaaa
    14521 actgcgcgag cgtttcccaa atgcccgtat catcaatgct tacggcccaa cagaagcgac
    14581 agtagctctg tcagcagttg ccgtgacaga cgagatgtta gcgactctca aacgcctacc
    14641 aatcggctat accaaggctg attctccaac ctttatcatt gacgaggaag gaaataaact
    14701 gccaaatggc gaacagggag aaatcattgt ttctgggcca gctgtttcaa aaggttatat
    14761 gaacaatcct gaaaaaacag cagaagcctt ctttgagttt gaaggtctgc cagcctatca
    14821 cacaggcgat gtgggaacca tgacagatga gggcttgctt ctctacggcg gacgcatgga
    14881 cttccagatt aagttcaacg gttaccgcat tgagttagaa gatgtctctc aaaacctcaa
    14941 caagtctcgc tttatcgaat ctgctgtcgc agtaccgcgc tataacaagg accacaaggt
    15001 acaaaatcta ttggcttatg tcatcttaaa agacagtgtt cgtgagcagt ttgagcgaga
    15061 tatcgatatt accaaggcca tcaaggaaga cctgacagac atcatgatgt cctacatgat
    15121 gccatctaaa ttcctttacc gagacagttt gccactgact ccaaatggaa agattgacat
    15181 caaaggattg attaacgagg tgaataagag atgatggagt tttttcaaca gcttcctcat
    15241 ttagagccat atggcaatcc tcagtatttt gtttatgtga ttgctgcaac cttgcccatc
    15301 tttataggcc tctttttcaa gaaacgcttt gcctggtatg aagtgttggt aagtctcttc
    15361 tttattgtca ccatgttggt gggtggaaag accaatcaac tagctgcctt gggtatttac
    15421 ctttgctggg aaatattgct cctgcttttc tacaagcatt atcgaaaaag caaggatggc
    15481 aagtgggtct tctacttagt tagttttctg tccctacttc cgattatctt tgtcaaggtg
    15541 caaccagcta tcaatggaac gcagtctttg cttgggttct tgggaatttc ttacctgacc
    15601 tttcgttcgg ttgggattat catcgagctg agagatggag tgattaagga ttttaccctc
    15661 tgggaattcc ttcgtttcct tctcttcatg ccaactttct cgagtggtcc aatcgatcgc
    15721 tttaagcgat ttaatgaaaa ttatcaggct attcctgagc gagatgagtt gatggatatg
    15781 ctggatgaat ctgtccgcta tatcatgtgg ggctttttgt ataagtttat cctagctcat
    15841 gttttaggag agaccttact acctcctctg aagaatttag ccttgcagtc aggtggcttc
    15901 tttaatctct atgccttggc agttatgtat acttttggtc tggagctctt ctttgacttt
    15961 gcaggttatt ctatgtttgc tttggccatc tcaaacttga tgggaatccg tagccctatc
    16021 aactttaaca agcccttttt atcaagggat ttaaaggagt tttggaatcg ctggcatatg
    16081 agtctgtcct tctggttccg tgactttgtc tttatgcgaa tggtgatggt gttaaccaga
    16141 aagaaagtct ttaaaaatcg taatgtaacc tcaagcatgg cctacattgt aaatatgctg
    16201 attatgggat tttggcatgg tgtgacctgg tactatatcg cctatggact ctttcatgga
    16261 ctaggcttgg tcatcaatga tgcctgggtt cgcaagaaaa aaacgctcaa taaggaacgg
    16321 aaaaaagcag ggaaggctgc cctacctgag aatcgctgga ttcagttgct tggcatggtt
    16381 atcactttcc atgttgtcat gttgtcattc ttaatctttt ctggattctt gaataatcta
    16441 tggtttaaaa aataaaagga aataaaatat ggatatcaaa tcagaagtta ttgaaattat
    16501 tgatgagttg tttatggaag atgtttctga catgatggat gaagatcttt ttgatgcagg
    16561 tgtcttggat agtatgggaa cggttgagtt gattgtggag attgagaacc gttttgacat
    16621 tcgtgtccct gtaacagagt ttggtcgtga cgactggaat acagctaata aaatcatagc
    16681 tggtattgtg gagctacaaa atgcttaaac gcttatggat gatcttcgga ccggtcttga
    16741 tcgctggttt gttggttttt ctgctcattt tcttttatcc tactgagatg catcataatc
    16801 taggagctga aaagcgttca gcagtggcta ctactatcga tagttttaag gagcgaagtc
    16861 aaaaagtcag agcactatct gatccaaatg tgcgttttgt tcccttcttt ggctctagtg
    16921 aatggcttcg ttttgacggt gctcatcctg cggtattagc tgagaaatac aatcgttcct
    16981 accgtcctta tcttttagga caggggggag ctgcatcgct taaccaatat tttggaatgc
    17041 aacagatgct accacagctg gagaataaac aagttgtgta tgttatctca cctcagtggt
    17101 tcagtaaaaa tggctatgag ccagcagcct tccagcagta ttttaatgga gaccagttga
    17161 ctagttttct gaaacatcaa tctggggatc aggctagtca atatgcagcg actcgcttac
    17221 tgcaacagtt cccaaacgta gctatgaagg acctggttca gaagttggca agtaaagaag
    17281 aattgtcgac agcagacaat gaaatgattg aattattggc tcgttttaat gaacgccaag
    17341 cctccttttt tggtcagttt tcggttagag gctatgttaa ctacgataag catgtagcta
    17401 agtatttaaa aatcttgcca gaccagtttt cttatcaagc aataggagat gttgtcaaag
    17461 cagatgctga aaaaaatact tccaataatg atctgggaat ggaaaattat ttctataatg
    17521 agcagatcaa gaaggatttg aagaaattaa aggattctca gaaaagcttt acctatctca
    17581 agtcgccaga gtataatgac ttgcagttgg ttttaacaca gttttctaaa tctaaggtaa
    17641 acccgatttt tatcattcca cctgttaata aaaaatggat ggactatgct ggtctacgag
    17701 aggatatgta ccaacaaacg gtgcagaaga ttcgctacca gttagaaagt caaggtttta
    17761 ccaatatagc agatttttct aaggacggcg gggagccttt ctttatgaag gacaccattc
    17821 accttggttg gttgggttgg ttggcttttg acaaggcagt tgatcctttc ctatccaatc
    17881 ccacaccagc tccgacttat catctgaatg agcgcttttt cagcaaagat tgggcgactt
    17941 atgatggaga tgtcaaagaa tttcaataga taatataata tagaagagtt caagaatgaa
    18001 actagttttc acgttttttc ttgactcttt ttttgcttgt gatataatta actggtaaat
    18061 aaaatgtcaa agaatagtat ttttctctta aaaaagagaa gtctaaaagg aaaggagtca
    18121 gatatgagac agctagcaaa ggatatcgat gcttttttga atgaggtgat tttgcaggcg
    18181 gaaaatcagc atgaaatcct aataggtcat tgcactagcg aggtggctct gacaaatacc
    18241 caggagcata tccttatgct cttgtcagag gaatctttaa caaattcaga attggcccgt
    18301 cgtctcaatg tcagtcaggc ggcagttacc aaggccatta agtctttggt caaggaaggg
    18361 atgttggaaa catctaaaga ttctaaagat gcgcgtgtga ttttttatca gttgactgac
    18421 ttggctcgtc caatcgctga ggagcaccac catcatcatg agcatacact tttaacctat
    18481 gaacaagtgg cgactcagtt tactccaaat gaacaaaaag tgattcagca gtttttgact
    18541 gctttagtag gagaaatcaa ataatgagat atattacggt agaggatttg tccttctatt
    18601 atgataagga gcctgttctt gaacatatca attatagtgt tgatagtggg gaatttgtta
    18661 ccttgactgg ggaaaatgga gcggctaaga cgacgctcat caaggccagt cttggaattc
    18721 tgcaaccacg cattggaaag gtgactattt caaagacaaa tacgcaaggt aagaaattga
    18781 gaatagccta tcttcctcaa caaattgcca gttttaatgc tggttttcca agtacggtct
    18841 atgaatttgt caagtcgggt cgctatccga gaaaaggatg gttccgtcgt ttgaatgctc
    18901 atgatgagga gcatatcaag gccagtctgg actcagttgg catgtgggaa catcgagaca
    18961 aacgcttggg gtctctttct ggagggcaaa agcagcgagc ggtgattgcg cgtatgtttg
    19021 cttctgaccc agatgtgttt atcctagatg agccgacaac gggtatggat gcaggaagta
    19081 aaaatgaatt ttacgaactc atgcaccaca gcgcccatca tcatggcaag gctgttttga
    19141 tgattaccca tgaccctgaa gaagtgaagg actatgcgga tcgcaatatt catctagttc
    19201 gtaaccaaga ctcgccatgg cgttgtttca acgttcatga gaatgatcag gaggtgggcc
    19261 atgcttagtt tattatctta tgactttatg cagcgtgcct ttctggctgt tattgccatg
    19321 agtcttttct cgccagttct tggaaccttc ctcatcttgc gtcgtcagag tttgatgagt
    19381 gataccctca gtcatgtctc actttcaggt gtagcttttg ggttggtttt ggggatttcg
    19441 ccaactgttt ctacgattgc tattgtcttg attgcggcgg tctttctgga gtatctccgt
    19501 acggtttaca agagctttat ggaaatcggg acagctattc tcatgtcaac aggtctggct
    19561 gtttctctga ttgtcatgag taagggtaaa agctctagtt caatgagttt ggaccaatat
    19621 ctctttggtt cgatcgtgac tatcagtgaa gaacaggtca tttccctctt tgtcattgcg
    19681 gcggttgttt tgattttgac ctttctcttt cttcgtccta tgtatatctt aacttttgac
    19741 gaagatacgg cctttgtgga tggcttgcca gttcgtacca tgtccattct ttttaacatg
    19801 gtgacagggg tggccattgc ccttatgatt ccagctgcgg gagctcttct ggtatcgact
    19861 atcatggtct tgccagctag tattgccctg cgtctgggga aaaactttaa atcggttatg
    19921 ctgcttgcca gtgctattgg atttttggga atggtagcag ggctttacat ttcctactat
    19981 gcagaaacac ctgcaagtgc aagtattacc attatttttg taactgtttt cttgctaatc
    20041 agtttagtaa gacgttttat caaataggag aatatcatga aaaaaattag cttattgcta
    20101 gccagtctat gtgccttgtt tttagtggct tgttccaatc aaaagcaggc agatggcaaa
    20161 ctaaatatcg tgacaacctt ttaccctgtc tatgaattta ccaagcaagt tgcaggagat
    20221 actgctaatg tagaactcct aatcggtgct ggtacagaac cccatgaata tgaaccgtct
    20281 gccaaggcag ttgccaaaat ccaagacgca gacacctttg tttatgaaaa tgaaaacatg
    20341 gaaacatggg tacctaaatt gctagatact ttggataaga aaaaggtcaa aaccatcaag
    20401 gcaacagggg atatgttgct cttaccaggt ggtgaggaag aagagggaga ccatgaccat
    20461 ggagaagaag gccatcacca tgagttcgat ccccatgttt ggttatcacc agttcgtgcc
    20521 attaaactag tagagcatat ccgtgatagc ttgtcagcag attatcctga taaaaaagag
    20581 acctttgaga agaatgctgc tgcctatatt gaaaaattgc aagccttgga taaggcttat
    20641 gcagaaggct tgtttcaagc caaacaaaag agctttgtga ctcaacacgc agcctttaac
    20701 taccttgcct tagactatgg actcaaacaa gtcgcaattt caggcctctc tccagatgca
    20761 gagccatcag ctgctcgctt ggcggaattg acagagtacg tcaagaaaaa taagattgcc
    20821 tatatctact ttgaagaaaa tgcttcacaa gcccttgcta acacactttc aaaagaagca
    20881 ggtgtcaaaa cagatgtcct caatcctttg gaaagtctga cagaagagga taccaaggct
    20941 ggcgaaaact acatttccgt gatggagaaa aacctcaagg ctctgaaaca aacaacggac
    21001 caagaaggcc cagcaatcga gcctgaaaag gcagaggata ccaagacagt tcaaaatggt
    21061 tactttgagg atgcagctgt caaggatcgc accttgagtg actatgtagg taactggcaa
    21121 tcagtttatc ctttccttga agatggcacg tttgaccaag tctttgacta caaggctaag
    21181 ttgactggta agatgaccca ggctgagtac aaggcttact atacaaaagg ctatcagaca
    21241 gatgtgacta agattaatat tactgataat actatggaat ttgttcaagg tggacaaagc
    21301 aagaaattca cctacaagta tgttggtaag aaaatcttga cttacaagaa aggcaatcgt
    21361 ggtgttcgct tcctctttga agccacagat gctgacgctg gacaattcaa atatgttcag
    21421 tttagtgacc acaatatcgc cccagttaag gcagaacatt tccatatctt ctttggaggc
    21481 acaagccaag aagccctctt tgaagaaatg gataactggc caacctacta cccagataac
    21541 ctatctggcc aagaaatcgc ccaagaaatg ttggcacatt gatgagaaaa ccggctagtt
    21601 cataagagct agtcggtttt tgggtactag atggctaact tcactataga ccttacagaa
    21661 ctgtaaaaaa taaataaaac tcttgaaata tctgggcctg tatgttagaa taaacttgat
    21721 aagcaaggtt cattagaaca ccaaagcccc taactattgc cgtagttaag ggcttttttg
    21781 acgtatctta gcgatttaac gggtgttgat aggctagtca gtcggtctac ttcttaccat
    21841 ctagtcattt gcagacgaaa tacaagataa ttcctgcgat gacgtccgct ataatagtaa
    21901 gagcgagctc tatgataagg ttcattagtt tcacctcctc tcacgaaccg taaggaacgt
    21961 aatcggtaac cgatgacaaa aatagtatac cacaataaat ttagaccatc aaccttactt
    22021 aatgcttgaa atcttggggt ttatatgcta gaatatagtt aattgataag gttcattaga
    22081 acaccaaagc ccttaactat tgccgtagtt aagggctttt ttgacgtatc ttagcgattt
    22141 aacgggtgtt gataggctag tcagtcggtc tactccttac
//
LOCUS       DAVDZK010000036        21818 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVDZK010000036 DAVDZK010000000
VERSION     DAVDZK010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21818
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.037"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            129..809
                     /locus_tag="VUX16_001648"
     CDS             129..809
                     /locus_tag="VUX16_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124571.1"
                     /translation="MYNQKLIKMVKGLFVGFIAVLCIILGYSIAQVQQNLRQNSQVQE
                     EAKQKPEEKQQEQLSLTEQQVEEFLIAYYTKKDLEENRPRYKPFMTDSMYQETVQEEQ
                     KPVNQTYKGYVVDQAFESGSIYIDKQHKIALAQVQYTSTTLTEKDNRASKGLTGSTKA
                     TIRLTYVEKAGKLLINKIEPIVLTEARGQSVGTYADTSSSSSTPVSSTSTATPTSSEP
                     TTATSSNQ"
     gene            820..1059
                     /locus_tag="VUX16_001649"
     CDS             820..1059
                     /locus_tag="VUX16_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124572.1"
                     /translation="MNKKIEQLEGKLEKVRKDKEKAQRQKEEADKKIKNYINQEKDLE
                     AQLFVALSEESGLSYQEMKELILPAQSSNQGVNHV"
     gene            1052..1951
                     /locus_tag="VUX16_001650"
     CDS             1052..1951
                     /locus_tag="VUX16_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124573.1"
                     /translation="MYKIINQLTNQEETFEYRDDLLSRLEIINERMKSNKINGIYRLY
                     SLNSEGEILQEESLEIPFVGIIDQLLENFGMSAGKKKKGLLHFLEKHKEKNSSLGTPE
                     IQLQPEFQPEPDPELEDLTVTKEANMARQIIAELVSQKPRDEVREEVPLEDKMTYSSS
                     EWTTDHFSRLDENEEERVEPSQDMPTQEVVSIVEKSTQEEKIPLSVKEDKGNVETSFS
                     LSHVTSVNLPSEVIDSFEAQTVTYKQSIKHKIQSNEEFIKEANEEINECQNKINELRQ
                     QILAKEKQASQLKDLYFKIEEVS"
     gene            1953..2501
                     /locus_tag="VUX16_001651"
     CDS             1953..2501
                     /locus_tag="VUX16_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124574.1"
                     /translation="MEQEQVVAQLGRATLVTGEIILKGLFLVSSKAVEMYQARGENVL
                     FTGETDWNKFMATADTKEVQQLLNNEVNLEAVRKELGQYGIGFSFYTHPDGKTTLAFN
                     AKDKGVVEQAFKDVLEGITRDPRGFNERNLKNGKTTSFEEKLQHFKAVEQEKISSLQV
                     NIHTKEFVLSENIEPQIGGKMK"
     gene            2498..4333
                     /locus_tag="VUX16_001652"
     CDS             2498..4333
                     /locus_tag="VUX16_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET8124575.1"
                     /translation="MITEKKKRRLRPYLLLGIGLFYFFHWLFKLWLLAPDTDSVTDVF
                     GLGKLNWMSDHLNDKSWFDFQFTPTSLLIGMSGFLIAFLLYLRVTDTGTYRYGEEHGS
                     ARFATREELMRFRDEEPEKNMIFTQNSQMGLFNNRLSFENQINKNILVYGGTGDSKTR
                     SAVKPNILQGNSSFVTTDTKGILIHETGKSLVEKGYKMKIFDLITFLNSDGFNVFRYI
                     HNEMDIDRVAEAITESLNRNGHESDPFWPAANKLLMRSLIGYLYFDGQIDHYLPNLGQ
                     VTDMIRELRRNHPEAESPVELMFEDLERRSPGNYACRQWKLFNKNFDGQTRTSVYAIF
                     ATTFSVFDHEQLRKIIEKDTLEIEKWNIEKTAVFIHIPEVDPAYQFLSALLFSTVFDV
                     LIKTADAVILGEHPTKIKEDLLHLQVWADEFGQIGKIPNLPPIISVIRSREISIKMMV
                     QSQSQIEVLYGKENTKTIINNCGAILYLGSNDLDTLKYLSERSGKQTLNDQNYSESRG
                     RNASSSKQNSKIGRELLTPHEVATIGTTEALLFLSKQNVFRDQKFNLDTHPRAYLLSN
                     GSNDDNWYRYKRYLSDIDEWKAQVGEENVIYIGIKEVEEVPLKVS"
     gene            4674..5081
                     /locus_tag="VUX16_001653"
     CDS             4674..5081
                     /locus_tag="VUX16_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124576.1"
                     /translation="MKSTIKNYYEMWTKRHERRYREALGYYNQQSKEALLAELTELEI
                     KKERSSRSWKLLVGLVLTIIFSDDLKRLLAILFSPLTGVPTNKLHESVLPSISIALFI
                     VLLFLTILIYNFSYSLLLRRYLILKRYIEEHYT"
     gene            5097..5570
                     /locus_tag="VUX16_001654"
     CDS             5097..5570
                     /locus_tag="VUX16_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124577.1"
                     /translation="MYRDRFFEVLESPYTPYVAIELIYAIVVICFNLNLGNLNKQLTH
                     HFDIDKMINQKDVSIASNVMSYENNISWHFLFFGILLIIIGFIIPILFSIINKSSYKR
                     EEIKNAIWFIIAIVIVVNFFLIISISRALLSPIIIATLIVCAVGATLGSLAISNT"
     gene            5845..7194
                     /locus_tag="VUX16_001655"
     CDS             5845..7194
                     /locus_tag="VUX16_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124578.1"
                     /translation="MNTLPQKQFKRMKREVEEETARGIGYFEGILEHIPSYPLSEAVK
                     ELALSGWITPHTDVIDVQNMIVTESIKWMNYQDFKEVAPYLFSYPREQREKDLLVQPV
                     KISREYFEELKANAEELFHLKQDLLQVNNQLDAKIQELEMDQLPNGDQVIGVDLKAEE
                     VLLLRTPENAQVEEWEVRKDGLITDYRSNLSEYAQIVDALLEMENPEIDTILYEEVIN
                     YSKKTWPDSEPIQLPENIKELLNQEGKLDPSYYQIAQFETVKQAYIYGMISPSFQERF
                     PHYSDFIRNYVEDREQYEFFNYRTEAVSLAQEILVPRLGDINQILGTNNQELIVQEVV
                     GYSQGESWELAYLRDTKTEDRESVRFYLESEIGAWYKGSLTELAVIRFEDIDLEKGFN
                     GHQEAVYHIDENLLVQDKLKQAQLHFPDLKHFVEAEELEREQTQDIVAEKEEPEFSL"
     gene            7206..8468
                     /locus_tag="VUX16_001656"
                     /pseudo
     CDS             7206..8468
                     /locus_tag="VUX16_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604856.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
     gene            8472..9333
                     /locus_tag="VUX16_001657"
                     /pseudo
     CDS             8472..9333
                     /locus_tag="VUX16_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730738.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toprim"
     gene            10636..10944
                     /locus_tag="VUX16_001658"
     CDS             10636..10944
                     /locus_tag="VUX16_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124579.1"
                     /translation="MIEHLKQETFDLLMEIFFEDEATDSPKVNEVNQHISRKECLYIL
                     RRDMRIKTNYELEEVEMYPIVLKEIEGMSDERFEQLRDEILKMEMVDTMELILEDLKV
                     "
     gene            11167..11535
                     /gene="mobC"
                     /locus_tag="VUX16_001659"
     CDS             11167..11535
                     /gene="mobC"
                     /locus_tag="VUX16_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HET8124580.1"
                     /translation="MENGEKRKRPVQKLIRLTEEENRFISTKVAESGMTNFNAFARIM
                     LIMGEVKILNFEELRELRKEINRIGVNINQVAKKVNEDDQASLTELSQILELQKYLKD
                     TVSQFIQKQENQTKEQERWL"
     gene            11526..13202
                     /locus_tag="VUX16_001660"
     CDS             11526..13202
                     /locus_tag="VUX16_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HET8124581.1"
                     /translation="MVVTKVLQIKGVASLGRSTKYIEDEAKTVELTDTKSLNNALRYI
                     ENPSKTSFLEQDEQFEFPAVVKDGRVVKQLVSTYGITDASTATEEFLLTKKNAAQRAG
                     TKERSDIHNPNRVLAHHIIQSFSPEDDWTPQEIHEIGRKTILELTGGQHEFVIATHMD
                     KGHIHNHIIFNSTNSVTLKKFRWQKNTARSLFNISNKYSDLAGAKILKERLWTNRKTY
                     HAYRKKNSFRYEIKSRLDFLLKHSTSLEDFKIKARALNLEVDTSGKEIKYLLTDRDQT
                     RNVRDRTLSKKGNYSLEKISEKVVANEVTLSVDEIKSEYEKMVAEREDDFEMRITVEE
                     WQVMEETKNGIYLEMEFGLRNKGTILIPAHQIERAEDGSYEIFIRKNDFYYFVNPEHA
                     DKNRYMKGETVASQLSYDNGEMIIRKNPKISTLDQLVREYNYLSAHGVTEGQQFDELL
                     NRFEEELEEVDNLLDKLDQRLGELNKIQSAFLALESSDPQEVKLAIAIMKDLRVDPST
                     RKSEIDKLVKEATFERQTLYQRVEAITKDYKLHQDIEKNVEQRKEIETSL"
     gene            13278..14084
                     /locus_tag="VUX16_001661"
     CDS             13278..14084
                     /locus_tag="VUX16_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HET8124582.1"
                     /translation="MKIITFAAIKGGVGKTTLTFNYGEWLARKGHNVLFIDLDHQCNL
                     TQCYNIYESQNTIANAFKGGDVDIKHIKENISLIPGSVQLDTVERDLENSDKKNMLLY
                     LWLEDNYEKKKLGQFDYILIDCRPDFATATKNAVAVSHAIISPLTPSEFGYNAKFNLS
                     TRLEAFRKDVIDYRTRESYITAELYFLANMIRPNYGSSRELLEALGLEAKEKGTDNLL
                     GIVPAKELFNHSTIDKVSIADMKEKPDLYQKHKKFFMELEETFSRIYDTI"
     gene            14137..14358
                     /locus_tag="VUX16_001662"
     CDS             14137..14358
                     /locus_tag="VUX16_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124583.1"
                     /translation="MAFTPKEKEISQIIEATHQPEQLPDIDSFESFERKKQFQFTLKP
                     SNRKKLDQVAKAAGAKSASDYLDKLIEKL"
     gene            14423..15199
                     /locus_tag="VUX16_001663"
     CDS             14423..15199
                     /locus_tag="VUX16_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HET8124584.1"
                     /translation="MDLITRLLAEREGKVHGGIYDITQKRFAYNSNRIEGSRLTEEQT
                     SLIYETKTIANIDAKGIKIDDLVEMNNHFKCFDYILDTVNEPLTEDHIKTLHRVLKSG
                     TSSEHNPIAPVGRYKVLQNEVGKIATASVEQTEDEMLSLLIGYDLKKQKDLNYLTSFH
                     AQFERIHPFADGNGRIGRLLLYKQCLKEGLTPFIVDDINKATYYSALEAFQVHDNRQL
                     LFDYFQSEQLFYMNYLKNKGFEGAINDEKEGDFIKKSDKF"
     gene            15578..16899
                     /locus_tag="VUX16_001664"
                     /pseudo
     CDS             15578..16899
                     /locus_tag="VUX16_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397931.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISLre2 family transposase"
     misc_feature    17277..17408
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            17424..17954
                     /gene="infC"
                     /locus_tag="VUX16_001665"
     CDS             17424..17954
                     /gene="infC"
                     /locus_tag="VUX16_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET8124585.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            17987..18187
                     /gene="rpmI"
                     /locus_tag="VUX16_001666"
     CDS             17987..18187
                     /gene="rpmI"
                     /locus_tag="VUX16_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET8124586.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            18239..18598
                     /gene="rplT"
                     /locus_tag="VUX16_001667"
     CDS             18239..18598
                     /gene="rplT"
                     /locus_tag="VUX16_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET8124587.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            18656..19036
                     /locus_tag="VUX16_001668"
     CDS             18656..19036
                     /locus_tag="VUX16_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET8124588.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLESLHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            19286..20086
                     /locus_tag="VUX16_001669"
     CDS             19286..20086
                     /locus_tag="VUX16_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET8124589.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKVNKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHGRGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            20097..21035
                     /locus_tag="VUX16_001670"
     CDS             20097..21035
                     /locus_tag="VUX16_001670"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET8124590.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKTILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENFPKVMDKYGISSLEELRQEVKESLR"
     gene            21077..>21818
                     /gene="lytB"
                     /locus_tag="VUX16_001671"
     CDS             21077..>21818
                     /gene="lytB"
                     /locus_tag="VUX16_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET8124591.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAADEWVFDTHYQSWFYIKADANYAENEWIKQGDDYFYLKSGGY
                     MTKSEWVEDKGAFYYLDQDGKMKRNAWVGSSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDRQYQSWFY
                     IKENGNHADKEWIFENGHYYYLKSGGYMA"
BASE COUNT         7664 a         3388 c         4681 g         6085 t
ORIGIN      
        1 acgttaatag cgatggtagt ttcttagttt cagaaatgaa ctttggtggt ttatatgtat
       61 caagttggcg taccttgaaa ccacaatcag gtatctattt tgttacccct aaataagaaa
      121 ggaaaagaat gtataatcaa aagttaataa aaatggtaaa gggactcttt gtgggattca
      181 ttgccgtttt atgtattatc ctgggctatt ctattgctca agtacaacag aatttgagac
      241 agaatagtca agttcaggaa gaggcgaagc aaaaaccaga agagaaacaa caggaacaac
      301 tatctcttac tgaacagcag gtcgaggaat ttttaattgc ttactataca aaaaaggatt
      361 tagaagagaa tcgaccacgc tataagcctt ttatgacgga ttctatgtat caggaaactg
      421 ttcaagaaga acaaaagcca gtcaaccaga cctataaggg gtatgtggtt gaccaagctt
      481 ttgaatcagg atctatttac attgataaac aacataaaat tgctttagct caggttcaat
      541 atactagtac cactctaaca gagaaagata atagagcttc taaggggctt actggtagca
      601 ctaaggctac aattcggttg acctatgtag aaaaagcagg gaaactattg atcaataaaa
      661 tagagcctat cgtattgact gaagcgagag ggcaaagtgt aggaacctac gcagatacta
      721 gcagttcaag ttcaactcca gtttcttcta catcaacggc aacaccgaca tcttctgaac
      781 caacaaccgc aactagtagt aaccaataag gagaatggaa tgaataaaaa aatagaacaa
      841 cttgaaggta agcttgagaa agtgaggaaa gacaaggaaa aagcgcaacg acaaaaagaa
      901 gaagcagata aaaaaatcaa gaattacata aatcaagaaa aagatttgga agcgcagctt
      961 tttgttgctc tatcagaaga aagtggctta tcctatcagg aaatgaagga actaatcctt
     1021 ccagcacaat caagtaacca aggagtgaac catgtataaa attatcaatc aactgactaa
     1081 tcaagaggaa acatttgagt accgagatga cttgttatca aggctagaaa tcatcaatga
     1141 acgaatgaag agtaataaaa taaatggaat ctatcgactt tattctctca attctgaagg
     1201 tgaaatccta caagaagaaa gtcttgaaat accttttgtt ggcatcattg atcagttgtt
     1261 ggaaaatttt ggtatgagtg ctggaaagaa aaagaaaggt ttgcttcatt ttttagaaaa
     1321 acataaagaa aagaactcct cactaggaac accagaaatc caactccaac ctgaattcca
     1381 accagaacca gaccctgaac tagaagatct aacggtaacg aaagaggcga atatggctcg
     1441 tcaaataatt gctgagctag tttctcagaa gcctcgagat gaggttagag aggaagtgcc
     1501 tttggaagat aaaatgacct attcttctag tgaatggact acagatcatt tcagtagatt
     1561 agatgaaaat gaggaagaac gagtagaacc ttcacaagat atgcctacac aagaagtagt
     1621 ttctattgtt gaaaaatcaa cgcaggaaga gaaaatacct ctttctgtta aagaagataa
     1681 gggtaatgtt gagacttcct tctccctttc tcatgtgact tcagtaaatt taccttcaga
     1741 ggttattgat agctttgagg ctcagacggt tacttataag caatctatta aacataaaat
     1801 tcagtctaac gaagagttta ttaaggaagc aaacgaggaa attaatgagt gccaaaataa
     1861 aattaatgag ttgcgacaac agattcttgc caaagagaaa caagctagtc aactgaagga
     1921 tctttatttt aaaattgaag aggtgagcta aaatggaaca agaacaagtt gtagcccaat
     1981 taggacgggc aactcttgtg acaggagaaa tcatcttaaa aggactcttt ctggtgagct
     2041 ctaaggcagt tgaaatgtat caggccagag gggaaaatgt cctctttact ggtgagacag
     2101 actggaataa attcatggca acggcagata cgaaagaagt ccagcaatta ctaaataatg
     2161 aagtcaatct cgaggcagtt cgaaaagaac ttggccaata cgggattggc ttttcttttt
     2221 atacacaccc tgatggtaag acaactcttg ctttcaatgc aaaagataaa ggagttgtcg
     2281 aacaggcctt taaggatgtc ctagaaggca tcacaagaga tccgagagga ttcaatgagc
     2341 gaaatcttaa aaatgggaaa acgacttctt ttgaggagaa attgcaacat ttcaaagcag
     2401 tggaacaaga gaaaatttct tccctccagg taaacattca tactaaggaa tttgttcttt
     2461 cagaaaatat cgaaccacag attggaggaa aaatgaagtg attacagaaa agaagaaacg
     2521 aagacttaga ccgtatttgt tgttaggcat tggtctattc tatttctttc attggctctt
     2581 taaactatgg ctgttagcac cagataccga ttcagtaaca gatgtatttg gacttggaaa
     2641 gcttaattgg atgagcgacc atctaaacga taaatcttgg tttgattttc aattcacacc
     2701 aacttcttta ttgattggta tgagtgggtt tctgattgca tttctgctgt atttgagagt
     2761 aacggataca ggtacgtaca ggtatgggga ggaacatgga tcggctcgtt ttgcgacaag
     2821 agaagagttg atgagattcc gagacgaaga acctgaaaag aatatgattt tcacccaaaa
     2881 tagccagatg ggattattta ataaccgatt gagctttgaa aatcagatta ataaaaatat
     2941 tctggtatat ggaggtacag gggattcaaa gacacgtagt gctgtaaagc cgaatatttt
     3001 acaaggaaac tctagttttg taaccacaga taccaaaggg attttgattc atgaaacagg
     3061 gaaatcactt gtagaaaaag gttataagat gaaaattttt gatttgatta ctttcctgaa
     3121 ttcagatggt ttcaacgttt ttagatatat tcataatgaa atggatatag accgagtggc
     3181 agaggcaatt acagaatctc tcaatagaaa tggtcatgaa agtgatcctt tttggccagc
     3241 agccaataaa ctcctgatgc gctctctaat tggctatctt tattttgatg ggcagattga
     3301 tcactatctg cctaatttgg ggcaggttac agatatgatt cgagaattga gacggaatca
     3361 tccagaagcg gaaagtcctg ttgaattgat gtttgaagac ctggagagaa ggagcccagg
     3421 gaattatgcc tgcaggcagt ggaaactatt caataaaaac tttgatggcc aaacacggac
     3481 ttctgtttat gccatctttg cgacaacctt ctcagtgttt gaccatgagc aactaagaaa
     3541 gattattgaa aaggatacac tggagattga aaaatggaat attgagaaaa cagcagtttt
     3601 tattcatatt ccagaagtgg atccagctta tcagttctta tctgcccttc tttttagtac
     3661 cgtttttgat gtgctaataa aaacggcaga tgcagttata ttaggtgagc atccaacaaa
     3721 gatcaaggaa gatttattac atctacaagt gtgggcagat gagtttggtc agattgggaa
     3781 gattcctaat ttaccgccaa ttatctctgt tattcgttct cgagagattt ctatcaagat
     3841 gatggtgcaa tctcaaagtc agattgaagt attgtacggt aaagaaaata cgaagacgat
     3901 tatcaataac tgtggtgcta ttctttattt aggttccaat gacttagata cgcttaagta
     3961 tctatctgag cgatcaggga agcaaacttt gaatgatcag aattatagtg agagcagagg
     4021 aagaaatgcc agcagttcta agcagaactc aaaaattggt cgagaactgt tgacaccgca
     4081 tgaggttgcc actattggaa caacagaagc cctactcttt ctatccaaac aaaatgtctt
     4141 tcgagatcaa aaatttaacc tggatacgca tccaagagct tacctcttaa gtaatggctc
     4201 gaatgatgac aactggtatc gatacaagcg ctatctaagc gatattgatg agtggaaagc
     4261 ccaggttggg gaagaaaatg ttatttatat tgggattaag gaagttgagg aagttcctct
     4321 taaagtaagt taggaaagaa agggaatcta atggaatttt atgactctta ttgcgtttta
     4381 attgctataa attgggatca gtatgtgtgg ttgcattagg aaggcgaaaa aataacctgg
     4441 catgaaaatt tagctcatgc aggttttttt cgtgatttta atacagctaa aagggtagcg
     4501 gaaactcatt tattagaaac ttttggagcc ataggattct ataagattgt tggtttttct
     4561 acagatgaac ttgggtatat agaaaccaag aactagagag cacaatgtgt tttagtattt
     4621 tgtgatataa tgaatggaga ataagcgatg attgagagga gtgtaataat cctatgaaat
     4681 ctaccataaa aaattattat gaaatgtgga cgaaacggca tgaacgtcga tacagagaag
     4741 ccttgggtta ctataaccag cagtctaaag aggcattgtt agcagaattg acagagctag
     4801 agataaaaaa ggaaaggagt tctcgcagct ggaaattatt ggtaggtctt gtattaacca
     4861 ttattttttc agatgattta aaacggcttt tagcaatttt attttcacct ttaacaggtg
     4921 tacctaccaa taaattgcat gaaagtgtgt taccgagcat cagtattgca ctatttatag
     4981 ttttgttatt tttgactatt ttaatctata actttagcta ttcgttgcta ctgagacgct
     5041 atctcatttt aaaacgctat atagaagaac attatacttg aatataggag ataaatttgt
     5101 atagagatcg attttttgaa gtattagaaa gcccttatac gccttatgtg gcaatagaat
     5161 taatttatgc aatagttgtc atttgcttta atcttaatct gggaaattta aataagcaac
     5221 taacacacca ttttgatatt gataaaatga taaatcagaa agatgtgtca attgcgtcta
     5281 atgtcatgtc atatgaaaat aatatatcat ggcacttttt gttttttgga atcttgttaa
     5341 ttatcattgg ttttataata cctatattat tttcaattat aaataagtct agttataaga
     5401 gagaagaaat aaaaaatgcc atttggttta ttattgccat agtcatagtg gttaatttct
     5461 ttttaattat ttcaatatca agagctcttt tgagtccaat catcatagca actttaatag
     5521 tgtgtgcggt aggagcaaca ttgggatctc ttgcaatttc taatacctaa aagtacaagg
     5581 cagccgtaat ggctgttttt ttgatgaaag gagaatcaaa tggatttaga acaattgaag
     5641 caacgacgag atgagctgat taaagataat tgagtgggcg gatggcttaa ttaaagagaa
     5701 ggaagaaaaa ctatggtaag tgaaagtgag aacgattgca gcttctgagc tagcgagatc
     5761 ggcattggaa tctgctttac gttctgcagg tatcgtagat accttttacg gaccagataa
     5821 tagaaagaaa ggaaatgaaa tagaatgaat acactaccac aaaaacaatt taaacgaatg
     5881 aagcgtgaag ttgaggaaga aactgctcga gggattggtt attttgaggg gattttagaa
     5941 catatccctt cttaccccct atctgaagcc gtaaaagagt tggctttatc tggctggatc
     6001 actcctcata cagatgtcat cgatgtccag aatatgattg ttacagaatc tataaaatgg
     6061 atgaattacc aggacttcaa agaagttgct ccctacttgt tttcttaccc tcgagagcaa
     6121 cgagagaaag atttattggt tcaaccagta aaaatctcca gagagtactt tgaggaatta
     6181 aaggccaatg cagaagaatt atttcacttg aaacaagatt tgcttcaggt taataatcaa
     6241 ttagatgcta agatccagga attggagatg gatcagctcc ccaatggtga tcaagttatt
     6301 ggagtggatt taaaagctga ggaggtattg ttgctacgaa ctccagaaaa tgctcaggtt
     6361 gaggagtggg aggttcgtaa agatggcttg attactgatt atcgttccaa tctttcagaa
     6421 tatgctcaaa ttgtagatgc tttacttgaa atggagaatc cagagattga tactattctc
     6481 tatgaagaag taatcaacta ttctaagaaa acttggccag attcagaacc aattcaactt
     6541 ccagaaaata tcaaggaact attgaatcaa gagggcaagc ttgatccctc atattatcaa
     6601 atagctcagt ttgaaacagt aaaacaagct tatatttatg ggatgatttc acctagtttt
     6661 caggagcgtt tccctcatta ttcagatttc attaggaact atgtagaaga tagagaacaa
     6721 tatgagtttt tcaactatcg tacagaagcc gtctcattag ctcaggaaat tctagtacca
     6781 cgtttaggag atattaacca gattttagga acgaataacc aggagttaat cgttcaagag
     6841 gtcgttggtt attctcaagg tgaaagctgg gaactagctt atttacggga tacaaagacg
     6901 gaagatagag aatccgttcg attctatctt gaaagtgaga ttggagcttg gtataaggga
     6961 agtttgacag agttggctgt tatccgcttt gaggatattg atttagagaa aggatttaat
     7021 ggccatcaag aagcagtcta tcatatcgat gagaacttgt tagttcagga taagctaaaa
     7081 caagcccaac tccattttcc tgatttaaaa cattttgtag aagcggaaga acttgagaga
     7141 gaacagacac aagatatagt agcagaaaaa gaagagccag aattttcatt gtagggggat
     7201 aacagatggt gttaagcaaa gaagaagcca aaagattatc tattatttct gttgcagagc
     7261 aactaggcat ggagttaaag cgtacaggta gctatagcta taactgggta gaacatgatt
     7321 cctttgtaat agatgcaaag aaaaatgaat tttactggaa ctcaagaact gaatttggag
     7381 atgtcattca gttagttcaa accatacgag gtgtttctta caaggaggcg atgaattttt
     7441 tagaaactgg agaatttaag gcagtagatg tagaagctca gacggcctca aaagagcctt
     7501 ttagttatca cttggaaaga tatgagcgtc aggatttcag cgcctctaga cgctatttga
     7561 aggcacagag aggcctttca gatgatacga ttaacttctt tattagccaa ggcagtatag
     7621 cggaagcaat ccgaaaaaaa ggagactatt ttgagcctgt gattgtcttt aaatataaag
     7681 acaacacaag ctttttagct ggagcgagtc ttcagggaat agtagagaat cgagagcact
     7741 atcctgaacg tgggcgttta aaacaaatta tgagaaattc agacggacaa ctaggatttt
     7801 caattgatat cggaacacca aaacgtttga tctttgcgga agctccaatc gatctaatga
     7861 gctactatga gcttcataaa gatagtcttc aggatgtccg cttagtagct atggatggag
     7921 taaaagaagg aatcattagt agacggttta tggaattgta tgcagagata aatgataaat
     7981 cctatcaagt taatcagaat actgggaaag ctctagaagt agtcgctaga acaacgaact
     8041 attttaaaga tggtcagaat caagatatga ttaccttggc tgtagataat gatatggctg
     8101 gctataaatt tataactagt ctgcaggaaa aggggattcc agtacagatt gcgattccgc
     8161 ctatcgttca gagatatcag gagaaggaag attggaatga ctttctgaag ggagggaata
     8221 aatttcctaa ggagttagca cacgtttata cagtagacga aaagtcttgg tattaccagg
     8281 gcttttttga gaaggaacta gctcttgcaa aagcgcaaga gctaactgca gatgatgtaa
     8341 aagcctttgt gtcagatagg caattgacaa aggaagaagt ccgtcaagaa tatacaagga
     8401 ttgtcgatca agagaaagaa aggaaacata ctatgtcgga agtacatgaa gcaggggctg
     8461 agtatgaagt agaaaagcca gataatagtc gcttagcgca agctagacga aagctggagc
     8521 gactcaaagg agaagctgat gaggcaatta atgcggccta ttcccaccaa gcactaacaa
     8581 atgggcaacc catgaatgat aagcgaggaa gtgctagctt tatgcgtaag caagaacaaa
     8641 tagaaggtca agtcttctca aagctggatg agattaggca acaggaagag cgagtagagc
     8701 gcctggagca ccaacaacat ttgaaagaaa tggggttgaa tcgtcaggga agtggtctgg
     8761 atatgagtgt tcaaaatata cctcgaatcc gtgaagagtt agaaaaagct aaacgtgggg
     8821 agtcgttctt taccaaagct actctcaaac gctatcaaga agagttgact agagttgagg
     8881 ccatatctga acaaatgggt aaaacgagca ttcaaccagc aactcaagcc ttaattgatg
     8941 aggggctagt gaaccagtgg caaaaacaac caaatacgta ttttgtaaaa ggattacgaa
     9001 gagttgccct ggagttgact gaagaaggag agtttcaatt atcttcacaa atcaagtatc
     9061 atccgaaaac agatgaggaa agactgaagg tggatgaatt acttgccaaa caaaggcaag
     9121 aaaatgtagg attaacgccc tcgaatcagg aaaaatcaat ctcaccacaa ccagagccta
     9181 ttgaaaaaaa tcaaggcgaa gcagggtggt tagaaaaaaa ttgggacaat ctcacgtttt
     9241 cgatagaaaa taaaaaaaac agtcgtcatt gatccgacta gtatagatga gatggttgaa
     9301 aaattacaag tcaaagattc gcaagagaca ctagataatc gatacgaaaa aatttatcag
     9361 tataaccgaa aagatgagag ggatcgtgat ttggatggtg atggtatttc caattctgat
     9421 gagatgttgc agggaacaga tccatacaac ggtgcctcta accttcataa aaaacaggaa
     9481 gatagagaaa gaaggacaga tgttgaagcg gaaactggag ctattataac cgatgcaatt
     9541 gctactaaaa gttcagaaca aaccatttcc cagttagtcg caaataaaga tacaaaagct
     9601 ttagctgaac acttgaaaga aggaatgaag aactacttgg attcagaaca gtttaaatca
     9661 ttcttggata cgatgagtaa gtttcacaac tactcactca ataatattca tttgctgaag
     9721 atgcaaaatc ctaatgtttc ccaagttgct agtttcaata aatggaaaac agattttgac
     9781 agaacagtta aaaagggttc aaaagctctg aaaatctggg ttccgtatca agtgaaaact
     9841 aagatttttg ctaatcaaaa tgagttgagt ttttctccat ctgagaatga aacggaagag
     9901 aaggaagtca cagttactcg attcaagtta gggaatgtct ttgatgtatc tcaaacagaa
     9961 ggaaaagaat tgccaaaagc aattaatgaa ttgactggag atgttaaaga ttatgaagat
    10021 ttgtaccgag cagccaaagc tgtttcaatg gataatcagg ttcctatcag ttttgaagaa
    10081 attaaaagag agagcacaaa tggttattac tctccagatg aaaatcgaat tgttatttca
    10141 aaaggcttaa agggtcaaga acagatttta aaaaccattt ttcatgaaat ggctcatgca
    10201 gatttacata gaggaagcaa tgcccaatat ggggacgacc aatatcgtaa gcaagaatta
    10261 caagctgaaa gtgtcgctta tgtcgtggct aatcattttg gttttgatac gagtagctac
    10321 agttttggct atttggctat ttgggcaaaa gataaaaatg gttttgaaga tatggtagaa
    10381 caactgcagg ttgttcagaa ggaagcaaaa agtttgattg atcggatgga tgctaagtta
    10441 gaattagtga aaaataaaac tgtgacgaaa gataagtttg ctgataaact ccaacaggca
    10501 aaagaaaaat ctgagcagtt ggggaatcaa aaggcggagg ctgtaaagca ggtggaagaa
    10561 aaaaagtccc tgagcaaccc tcgataatgg aggcattagt ccgtaggaag aaaaacaaaa
    10621 aaggagaaac ggaagatgat tgaacatcta aaacaagaaa cttttgatct tttaatggag
    10681 atattttttg aggatgaggc tacagattcg ccaaaagtga atgaagtcaa tcagcacatt
    10741 tcacgtaagg aatgtcttta cattcttcgt agagatatgc gaattaaaac aaactatgag
    10801 ctagaagaag tagaaatgta tcccattgta cttaaagaaa ttgaagggat gagtgatgaa
    10861 cgatttgaac aactaagaga cgaaattctt aaaatggaga tggttgatac aatggagctt
    10921 atactggaag acttaaaagt ttagtcaaac ttttccctcg tgataggata acattcctgc
    10981 ttgcagggat taggggattg gggatttccc caaagattta aaaaggtcaa agttagtcag
    11041 ggatgacacc ctgactaact ttgacctttt taaaaacagc atttggatat ccaagtgcta
    11101 atcttgccag aagaaaaggg ggcggacccc ctcagtcaaa aaatagcaga atagaggtgt
    11161 aaggttttgg aaaatggaga aaaacgcaaa agaccagttc aaaaattaat cagattaact
    11221 gaggaagaaa atcggttcat ttcaacaaag gttgcagaat ctggaatgac aaattttaat
    11281 gcttttgccc gaattatgtt gattatgggc gaggtcaaaa ttttaaattt tgaagaattg
    11341 agagaattgc gtaaggaaat aaatcggata ggcgtcaata ttaatcaggt cgcaaaaaag
    11401 gtaaacgaag atgaccaggc tagcctaact gaactgagtc agattcttga attgcagaaa
    11461 tatttgaaag atacagttag ccaatttatc caaaaacagg aaaatcaaac aaaggaacaa
    11521 gagcgatggt tgtaacaaag gttcttcaaa taaagggtgt agcttcttta ggacgatcta
    11581 caaaatatat tgaggatgaa gctaagacgg tcgagctgac tgatacgaaa agtttaaata
    11641 atgctttacg ctatatcgag aatccatcta aaacgagttt tttagaacaa gatgaacagt
    11701 ttgaatttcc agcagtggtt aaagatggcc gagtagtcaa gcaactggta tctacttatg
    11761 gaattacaga cgctagcaca gcgacagaag aatttctttt gaccaaaaag aatgctgctc
    11821 agcgagcagg gacaaaagaa cgatctgaca ttcacaatcc gaatcgggtt ttggctcacc
    11881 acatcatcca atcattttct cctgaagatg attggactcc acaagaaatt catgagattg
    11941 gtcgaaaaac aattttagaa ttaactggtg gacaacatga atttgtcata gcgactcaca
    12001 tggataaggg gcacattcac aatcacatca ttttcaattc cactaattct gttacattaa
    12061 aaaagtttcg ttggcagaaa aatactgcta gaagcttatt taatatttca aacaagtatt
    12121 ctgatttggc tggagctaaa attctcaagg agagattatg gactaatcga aaaacctatc
    12181 atgcctatcg caaaaaaaat tcttttcgct atgaaattaa atcacgctta gattttcttt
    12241 tgaaacattc aacctcttta gaggatttta agattaaggc acgagcttta aatcttgaag
    12301 ttgatacttc agggaaggaa ataaaatatc tcctgactga tcgggatcaa acaagaaatg
    12361 tgagggatcg tacactgtcc aaaaaaggaa attattcttt agagaaaatt tctgagaaag
    12421 tggttgctaa cgaagtaacc ttatctgttg atgaaataaa atctgaatat gaaaagatgg
    12481 tggcagaacg agaagatgat tttgaaatga gaatcacagt tgaagaatgg caggtgatgg
    12541 aagaaacgaa aaatggaatc tatcttgaaa tggaatttgg gcttagaaat aagggaacca
    12601 ttcttattcc agctcaccag attgaaagag cagaagatgg ctcttatgaa atttttatca
    12661 gaaaaaatga cttctactat tttgttaatc ctgaacatgc tgataagaat cgttatatga
    12721 agggagaaac agtcgcttcc cagttatcgt atgataatgg agaaatgatt atccgaaaaa
    12781 atcctaaaat ctcaactttg gatcagcttg ttcgtgaata taactatcta tccgctcatg
    12841 gagtgacaga aggacagcaa tttgatgaat tgctaaatcg ttttgaagag gaactagaag
    12901 aagtagataa cttacttgat aaactagatc aacgcttggg tgagcttaat aaaattcagt
    12961 ctgcatttct tgcattggaa tcaagtgatc ctcaggaagt gaaactagct attgctatta
    13021 tgaaagactt gagagtagat cctagcactc gcaaatctga gattgataaa cttgttaaag
    13081 aggcaacctt tgagcgccag actttgtatc aacgggtaga agcaattaca aaagattata
    13141 agctacatca agacattgag aaaaatgtgg agcagcgtaa ggagatagaa acttcattgt
    13201 aaaaaataag tataaatata tttacaaata taattataat ggtataatag aagtatagaa
    13261 aaggatggag aaatagaatg aagattatca catttgctgc tattaaaggc ggtgttggaa
    13321 aaacaacttt gacatttaat tatggagaat ggttggctag gaaagggcat aacgttctct
    13381 ttatagattt agaccatcaa tgtaatttga ctcaatgcta caatatttac gaaagtcaga
    13441 atacaattgc gaatgctttc aaaggaggcg atgtggatat taagcacatc aaggaaaata
    13501 tcagtctaat accaggttcg gttcagttgg atacagtgga gcgagattta gagaacagcg
    13561 ataagaaaaa tatgctcctt tatctttggt tagaagataa ctacgaaaag aagaagttgg
    13621 gtcagtttga ctatatcttg attgattgta gaccagactt tgcgacagct acaaaaaatg
    13681 ctgttgcggt tagtcacgct attattagtc ccttgactcc ttcagagttt ggttataatg
    13741 ctaaattcaa tctatcaact cggttagaag cgttcagaaa ggatgtaatc gattatcgta
    13801 ccagagagtc ctacattact gctgagttat attttctagc aaatatgatt cgaccaaact
    13861 atggatcatc aagagaatta ttggaagccc ttggacttga agccaaagaa aagggaacag
    13921 acaaccttct agggattgta ccagcaaaag agttattcaa tcattctacg attgataagg
    13981 tctctattgc agatatgaag gagaagcctg atctctatca aaaacataaa aagtttttta
    14041 tggagctaga ggagactttt tcaagaattt atgatacaat ataattatat ttgtaaacac
    14101 aaatacaatt ataaatataa ttagaaggag attatgatgg catttacacc gaaagaaaaa
    14161 gaaatttcac agattattga agcaactcat caacctgaac agcttccaga tatagatagt
    14221 tttgaaagtt ttgaacgtaa gaagcaattc cagtttactt tgaagccaag taatcggaaa
    14281 aagttagatc aagttgcaaa agcagctggt gcaaagtctg catcagatta tcttgataaa
    14341 ttaatcgaga aactatagtt atggatatat ttataactat aaacatatcc ataactacaa
    14401 ctgcttacta caaggagaaa taatggattt aattacaagg ctcttagcag agagagaagg
    14461 aaaagtacac ggtggtattt atgatattac acagaaacgc tttgcttata attctaaccg
    14521 aattgaagga agtcgtctga cagaagagca gactagctta atttatgaga caaagacaat
    14581 cgcaaatatt gatgcaaaag gaatcaaaat tgatgatttg gtagaaatga ataatcattt
    14641 taaatgtttt gattatatct tagataccgt taacgagcca ctgacagagg accatattaa
    14701 aacactgcat cgtgttctaa aaagtggaac aagttctgag cataacccga tagctccagt
    14761 tggtcgttat aaagtattgc aaaatgaggt aggaaaaatt gcgacagctt ctgttgaaca
    14821 gactgaagat gagatgcttt ctttactgat tggctatgat ttgaaaaaac aaaaagattt
    14881 gaattactta acaagctttc atgcacaatt tgaaaggatt catcctttcg cagatggtaa
    14941 tggtcgaata ggacgattgc ttttgtataa acaatgctta aaagaagggc ttaccccctt
    15001 tattgtggat gatattaata aggcgactta ttattcagcg cttgaagcct ttcaggttca
    15061 tgataacaga cagctattat ttgattattt ccaatctgag caactttttt atatgaatta
    15121 tcttaaaaat aaaggatttg aaggagctat caatgatgag aaagagggag acttcataaa
    15181 aaagtcagat aaattctaag aaaaggtgca acagtttaag ctaagaggag aaagtcatca
    15241 cttaaaaaag ttattataat tatatttaca aatataaaca taattataaa gtctgttgtt
    15301 ttttgttgta aaataccttc tattggttgc gagataataa tcttgacaac cgtactgagc
    15361 ctggttctta tatcaggctt ttattttacc ttgaaataga aacagttgaa cttctgatac
    15421 tcaactaaat cactttagta tctttcaata ataaataggg cgttgatttt aatttaaaga
    15481 aacagcctaa tttattcttg gaacaaaaat aaatttgatg acttgtttta aaaatcatac
    15541 aattttcata agaattgaaa gggaaatgaa aaattgtatg aaacaatttg atgaattgag
    15601 atttagtagc caggaacaag aaaagacaaa acaacatttt ttacagcata ttgaacagta
    15661 tgatgagtcg ataagctcca gtatgagatc aaaaggctat cgttgtaaaa atcaagctga
    15721 acgtaccgta gcttttacat ttggagaagt gaccttttct agaaaacgtt ggtataagaa
    15781 tggtgaatgt agaataccag ttgatgaaat gttaggatta gaaaagaatg tacgtcattc
    15841 acaggaacta ttgtatcaag ctgcggttct agctacaaaa ctaccctatc gtcaggtagg
    15901 agagacaatt gagatggttt ataatgtaac tgtcactaaa gataccgtca ataaggttgt
    15961 taaattagcc aatcaattac tagaagaaaa ggatgattat cgatttttta aagaagagaa
    16021 gaagattgaa aaattaaagc agatatcatc tacatagagg gagatggtgt atatgtgaaa
    16081 acatctgaag atggttctga aaaaaagaat atggatttat cacattttgt agttcataca
    16141 ggttctaaac agattggccc aaatcgtttt gagctagaaa ataaaaaaga gcttatccga
    16201 ttggataagc gctcagctcg tagagaattg ttggatttat tggaaaatga atatgaaatt
    16261 acaaatggga caatactagt tactaattct gactgtggca agggttatac accacatgta
    16321 tttactgaaa tcgctaaatc atttaatgtt aagaggcatg agcatttttg ggacgaatat
    16381 cacttgaata aagaaattaa agaatttaca aagtcttatc cgagagaatt gagagaagac
    16441 ttatttcaag ctattaaaga gcatgataag aaattattaa ggcgtacact agatactata
    16501 gaatcattgg ttagtagtga agagggagag gaaaaatttg aatattattc gagtaggtta
    16561 atgaggaatt ttcagtatac gaaaccagcg gaaatgaggg gacttccaaa ggcaggtatt
    16621 gggattatgg agagccagca tagaaaaata acgtatagaa tgaagcatag agggatgtat
    16681 tggacaagtg aaggtgggat agccgtagcg aatatgatat tgttagagcg tgaaggaaaa
    16741 ttaagagatt tattttttgg agaatggaag gaggactatg atgagtatac gtcattggat
    16801 catatcagtg cggatagtgt tcgacctaaa aatgactcta aagactacaa acttccccgt
    16861 ttacataaaa atatagaaaa gatatttaag atgaaataat ttaagtgcta atttcaacga
    16921 aaacacaaat ataaataagc aaaaatttct agtgagattt gggctttttt ggcgtggaat
    16981 aattgacatt tatcctgatt ttggtataat agagatataa aaaacaacga aaaaaggagt
    17041 tggaaatgag cctccaactc cgcagagtaa cacaacccaa acttgtatta ctcaatcaac
    17101 taaaatgata gcataagaaa aaatcattgt caagggctga gcatacaaaa atgtttagcc
    17161 ctttcgtgta tttgcattta tttatatgga aatctgggat ttctcaaaaa tcacgacaca
    17221 tacaaaataa ctttttatct tgacaagagc tagaaaactt ggtatcatat aaaagttgag
    17281 aaaagcagaa gtgagagctt ctcgccttgt gacattaagt tgcctggccc tacggatgaa
    17341 aagtttctaa gaaacgctat cataacgtgc gggcttgtat atttacaagt ccgctattgt
    17401 ttttctctaa taaaacaaaa gaggtgaaaa ccatagcaaa gcaagactta ttcatcaatg
    17461 atgagattcg tgtacgtgaa gttcgcttga ttggtcttga aggagaacag ctaggtatca
    17521 agccactcag tgaagcgcaa gctttggctg ataacgctaa tgttgaccta gtattgattc
    17581 aaccccaagc caaaccgcct gttgcaaaaa ttatggacta cggtaagttc aaatttgagt
    17641 accagaagaa gcaaaaagaa caacgtaaaa aacaaagcgt tgttactgtg aaagaagttc
    17701 gtctaagtcc aacaattgac aagggtgact ttgatacaaa acttcgtaat gcacgtaagt
    17761 tccttgaaaa aggaaataaa gttaaggtat ctattcgctt taagggtcgt atgattaccc
    17821 ataaagagat tggtgcaaaa gttttagccg agtttgctga agcaactcaa gatattgcca
    17881 tcatcgaaca acgtgctaaa atggatggac gtcaaatgtt catgcaattg gcgccagcga
    17941 ctgacaaaaa ataattgtca gaaagttaaa taaaggagaa aaaatcatgc caaaacaaaa
    18001 aacacaccgc gcatcagcta aacgtttcaa acgtacaggt tctggtggac ttaaacgttt
    18061 ccgtgcttac acttctcacc gtttccacgg aaaaactaag aaacaacgtc gtcatcttcg
    18121 taaagcatct atggtgcatt caggagatta caaacgtatc aaagcaatgc ttactcgctt
    18181 gaaataatag cttgactgta agtaaacaat tctaggaaat atttggagga aataaaacat
    18241 ggcacgtgtt aaaggtggcg ttgtatcacg caaacgtcgt aaacgtattc ttaaattagc
    18301 aaaaggttac tatggagcta aacacatctt gttccgtact gcaaaagaac aagtaatgaa
    18361 ctcttactac tatgcatacc gtgaccgtcg tcagaaaaaa cgtgacttcc gcaaattgtg
    18421 gatcactcgt atcaatgcgg cagctcgtat gaacggactt tcatactcac aattgatgca
    18481 tggtttgaaa ttggctgaga tcgaagttaa ccgtaaaatg cttgctgact tggctgttaa
    18541 cgatgcagta gctttcacag ctcttgcaga tgcagctaaa gcaaaacttg gtaaataaca
    18601 actgatgaga ctggaacagg attgtccagt ctttttaaaa ataaaggaga aagatatggc
    18661 ttcaaaaatg ctacacactt gcttacgagt agaaaatctt gaaaaatcaa tcgcatttta
    18721 tcaagatgct tttggtttta aagaattgcg tcgcagagat tttccagacc atgccttcac
    18781 gattgtctat ctaggtcttg agggtgatga ctatgagttg gagttgactt ataactacga
    18841 tcacggtccg tatgtggttg gtgatgggtt tgcccatatc gccctcagta cacctgatct
    18901 tgagtcactt catcaagagc acagtgcaaa aggctatgaa gtgactgagc caaatggtct
    18961 accaggaact acaccaaact attactttgt caaagaccct gatggataca aggtcgaagt
    19021 cattcgtgaa aaataatttc gtgcaagtta agtagaatat tcgttttcta cttgactttt
    19081 tttagctgaa agagtatact aataaaaatt caacctttaa ggggagtcca gagagactca
    19141 caaggtgtca gataaaagaa tagtgcaatt ttctagagga gactttttga atgtgctctc
    19201 ttgtgttgta cgattttaac tgaggccttg cactagcaag gtcctttctt tatctggtcc
    19261 ccttaaaatt taaggaggaa aagttatgaa tcccacatgt aagaagcgtt tgggtgtcat
    19321 tcggttggaa accatgaagg tggttgcaca agaggaaatc gcgccagcaa tctttgaatt
    19381 agtcctagaa ggagaaatgg ttgaagccat gcgagcaggc caatttcttc atctgcgtgt
    19441 accggacgat gcccatctct tacgtcgtcc tatttcaatt tcgtctattg acaaggtaaa
    19501 caagcagtgt cacctcattt atcggattga gggagctggg actgcaattt tttcaacctt
    19561 aagtcaggga gacactcttg atgtgatggg gcctcaggga aatggttttg acttgtctga
    19621 ccttgatgag cagaatcagg ttctccttgt tggtggtggg attggtgttc cacccttgct
    19681 tgaggtggcc aaggaattgc atggacgtgg agtgaaagta gtgacagtcc tcggttttgc
    19741 taataaggat gctgttattt tgaaaacgga attggctcag tatggtcagg tctttgtaac
    19801 gacagatgat ggttcttatg gcatcaaggg aaatgtttcc gttgttatca atgatttaga
    19861 tagtcagttt gatgctgttt actcgtgtgg ggctccagga atgatgaagt atatcaatca
    19921 aacctttgat gatcacccaa gagcctatct atctctggaa tctcgtatgg cttgtgggat
    19981 gggagcttgc tatgcctgtg ttctaaaagt accagaaagc gagacggtca gccaacgcgt
    20041 ctgtgaagat ggtcctgttt tccgcacagg aacagttgta ttataaggag aaaattatga
    20101 ctacaaatcg attacaagtg tctctacctg gtttggattt gaaaaatccg attattccag
    20161 catcaggctg ttttggcttt ggacaagagt atgccaagta ctatgattta gaccttttag
    20221 gttctattat gatcaaggcg acaacccttg aaccacgttt tgggaatcca actccaagag
    20281 tggcagagac gcctgctggt atgctcaatg caattggctt gcaaaatcct ggtttagagg
    20341 ttgttttggc tgaaaagcta ccttggctgg aaagagaata tccaaatctt cctattattg
    20401 ccaatgtagc tggtttttca aaacaagagt atgcagctgt ttctcatggg atttccaagg
    20461 caactaatgt aaaagctatc gagctcaata tttcttgtcc caatgttgac cactgtaatc
    20521 atggactttt gattggtcaa gatccagatt tggcttatga tgtggtgaaa gcagctgtgg
    20581 aagcctcaga agtgccagtt tatgtcaaat taaccccgag tgtgaccgat atcgttactg
    20641 tcgcaaaagc tgcagaagat gcgggagcaa gtggcttgac catgatcaat actctggttg
    20701 gaatgcgctt tgacctcaaa accagaaaaa caatcttggc taatggaaca ggtggaatgt
    20761 caggtccagc agtctttcca gtagccctca aactcatccg ccaagtagcc caaacaacag
    20821 acctgcctat cattggaatg gggggagtgg attcggctga agctgcccta gaaatgtatc
    20881 tggctggggc atctgctatc ggagttggaa cagctaactt taccaatcct tatgcctgcc
    20941 ctgacatcat cgaaaatttc ccaaaagtca tggataaata cggtattagc agtctggaag
    21001 aactccgtca ggaagtaaaa gagtctctga ggtaaactgc aatcaatctg ttcttgattt
    21061 tttattagtt tgtaatatga atttaggaga attttggtac aataaaataa ataagaacag
    21121 aggaagaagg ttaatgaaga aagtaagatt tattttttta gctctgctat ttttcttagc
    21181 tagtccagag ggtgcaatgg ctagtgatgg tacttggcaa ggaaaacagt atctgaaaga
    21241 agatggcagt caagcagccg atgagtgggt ttttgatact cattatcaat cttggttcta
    21301 tataaaagca gatgctaact atgctgaaaa tgaatggata aagcaaggtg acgactattt
    21361 ttacctcaaa tctggtggct atatgaccaa atcagaatgg gtagaagaca agggagcctt
    21421 ttattatctt gaccaagatg gaaagatgaa aagaaatgct tgggtaggaa gttcctatgt
    21481 tggtgcaaca ggtgccaaag taatagaaga ctgggtctat gattctcaat acgatgcttg
    21541 gttttatatc aaagcagatg gacagcacgc agagaaagaa tggctccaaa ttaaagggaa
    21601 ggactattat ttcaaatccg gtggttatct actgacaagt cagtggatta atcaagctta
    21661 tgtgaatgct agtggtgcca aagtacagca aggttggctt tttgacagac aataccaatc
    21721 ttggttttac atcaaagaaa atggaaacca tgctgataaa gaatggattt tcgagaatgg
    21781 tcactattat tatctaaaat ccggtggcta catggcag
//
LOCUS       DAVDZK010000037        21031 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVDZK010000037 DAVDZK010000000
VERSION     DAVDZK010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21031
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.038"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(<1..567)
                     /locus_tag="VUX16_001672"
     CDS             complement(<1..567)
                     /locus_tag="VUX16_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET8124592.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFW"
     gene            809..1480
                     /gene="sdaAB"
                     /locus_tag="VUX16_001673"
     CDS             809..1480
                     /gene="sdaAB"
                     /locus_tag="VUX16_001673"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET8124593.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            1489..2361
                     /gene="sdaAA"
                     /locus_tag="VUX16_001674"
     CDS             1489..2361
                     /gene="sdaAA"
                     /locus_tag="VUX16_001674"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET8124594.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            2383..3015
                     /locus_tag="VUX16_001675"
     CDS             2383..3015
                     /locus_tag="VUX16_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET8124595.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(3276..5126)
                     /locus_tag="VUX16_001676"
     CDS             complement(3276..5126)
                     /locus_tag="VUX16_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET8124596.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFHTLSGDELKQAIIAFANQTTHIE"
     gene            complement(5168..6325)
                     /locus_tag="VUX16_001677"
     CDS             complement(5168..6325)
                     /locus_tag="VUX16_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET8124597.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            6383..7549
                     /locus_tag="VUX16_001678"
     CDS             6383..7549
                     /locus_tag="VUX16_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET8124598.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPLSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            7688..8014
                     /locus_tag="VUX16_001679"
     CDS             7688..8014
                     /locus_tag="VUX16_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET8124599.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            8001..8594
                     /locus_tag="VUX16_001680"
     CDS             8001..8594
                     /locus_tag="VUX16_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET8124600.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            8587..9498
                     /locus_tag="VUX16_001681"
     CDS             8587..9498
                     /locus_tag="VUX16_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET8124601.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            9561..10625
                     /locus_tag="VUX16_001682"
     CDS             9561..10625
                     /locus_tag="VUX16_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124602.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(10803..11663)
                     /locus_tag="VUX16_001683"
     CDS             complement(10803..11663)
                     /locus_tag="VUX16_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET8124603.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEMQPILD
                     KDFKTLAQEK"
     gene            complement(11938..12924)
                     /locus_tag="VUX16_001684"
     CDS             complement(11938..12924)
                     /locus_tag="VUX16_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET8124604.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(13196..14671)
                     /locus_tag="VUX16_001685"
     CDS             complement(13196..14671)
                     /locus_tag="VUX16_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET8124605.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(14929..15852)
                     /locus_tag="VUX16_001686"
     CDS             complement(14929..15852)
                     /locus_tag="VUX16_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET8124606.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(15866..16795)
                     /locus_tag="VUX16_001687"
     CDS             complement(15866..16795)
                     /locus_tag="VUX16_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET8124607.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            17327..17551
                     /locus_tag="VUX16_001688"
                     /pseudo
     CDS             17327..17551
                     /locus_tag="VUX16_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17655..17810)
                     /locus_tag="VUX16_001689"
                     /pseudo
     CDS             complement(17655..17810)
                     /locus_tag="VUX16_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(17997..18608)
                     /gene="rpsD"
                     /locus_tag="VUX16_001690"
     CDS             complement(17997..18608)
                     /gene="rpsD"
                     /locus_tag="VUX16_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET8124608.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(18803..19855)
                     /locus_tag="VUX16_001691"
     CDS             complement(18803..19855)
                     /locus_tag="VUX16_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET8124609.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(19852..20550)
                     /locus_tag="VUX16_001692"
     CDS             complement(19852..20550)
                     /locus_tag="VUX16_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET8124610.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(20717..>21031)
                     /locus_tag="VUX16_001693"
     CDS             complement(20717..>21031)
                     /locus_tag="VUX16_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET8124611.1"
                     /translation="INVKETSDTANDQMKKSGMKPETPAPGTTNSMPADTMASSTNTM
                     AGENMAASANKMSDTMMSDDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNKKE
                     EN"
BASE COUNT         6201 a         4545 c         3950 g         6335 t
ORIGIN      
        1 ccagaagttt ttagcagctg tccatgaacc gtaacgtcct gcaacgtagg catctgctac
       61 acgttcttgg ttttcagctg agtagtcacc gttcaggtat gaatctgtta attggtaacg
      121 tccgatataa cgtccatttg tagctgtata gctaccacct gattcttttt gagcgatcca
      181 ttctttggct tctgcttcag atccgcttac agttgaaaca actgtttcac ttactactgg
      241 agtttctgcc actggagctg aaacagtttc atcttgagcg gctggtgccg cataagtagc
      301 tggcgctggt gttgcaacag gcgctacagg gccatcgata accaactctt gaccaacata
      361 aatcaaatga atgttatcaa tgtggttgtt ttctgccaat ttttcaactg ttgtgttgtg
      421 agtttcagcg atttctgaaa gtgtatcacc ttctttaaca gtgtaagttg atgattcttg
      481 agcagataca aatgatggag caaatactgc aaacaaggca gctactcctg caagagttgc
      541 tttaatcttt ttagttattg atttcatatt cgaaaattct ccttctttct atagttctat
      601 catacccttt aaatattacc gtttcttgac acttttatgt agaaatatta caaaattatt
      661 ttttatttcc ctaaataagg tgttttttgt cataaaagat actattttta tgctatttga
      721 ggtattagaa aggttttcat ccacaattaa agccaagccc ctcattcttt gatataatag
      781 agataagaat ttttataagg ggaaactgat gaaatcactt cgttttcaat ctgtctttga
      841 tatcatcgga ccagttatga ttggcccatc tagtagccat accgctggtg ctgttcgtat
      901 tgggaagatt gtctcttcca tttttgatga tactccgaca gaagttgaat tccaactttt
      961 taactcattt gccaagacct atcgtggtca cggaacagac ctagcccttg ttgcaggtat
     1021 tttaggaatg gatacagatg atcctgaaat tccaaatagt ctggaaattg cccacaagcg
     1081 tggtatcaag attgtctgga ccattcagaa agacagcaat gcccctcacc ctaacaccac
     1141 taaaattact gttaaaaatg cccacaagac catcagcgtg actggtattt ctatcggtgg
     1201 aggaaatatt caggtaaccg aactcaatgg ttttgccgtc tctctcaata tgaatacacc
     1261 gactatcatc atcgttcatc aagatattcc aggtatgatt gcccttgtta cagaggcgct
     1321 ttcccgctat ggtatcaata tcgcccagat gaatgtcact cgtgaaaaag ctggtgaaaa
     1381 agccattatg attatcgaag ttgacagtcg caactgtgat gaggctatcg aagaaattcg
     1441 aaaaatccct catctccaca atgtcaattt ctttaaatag gaggaagcat gttttattct
     1501 atcaaagaat tggtcgagca agcagatctg gactttcaag gaaatgtcgc agaactcatg
     1561 attacaacag agtttgaatt gaccggtcgc gaacgtgaag aagtcttcct tctcatggaa
     1621 cgcaatctgg aagttatgaa agcctctgtc caacttggcc tcaatgaaaa taaatctcgt
     1681 agtggcctga caggtggaga tgctgccaaa ttggatcact acatcgaaaa cggaaaaact
     1741 ctgtcagatt atacgattct ctcggctgcc cgaaatgcca tcgcagtcaa tgaacacaat
     1801 gccaaaatgg gcttggtctg tgccactcca accgctggaa gtgctggctg tctgccatcc
     1861 gttctcactg ctgctattga aaaattagac ctcagccacg agcaacaatt ggatttcctc
     1921 tttgctgctg gtgcctttgg actagtcatc gcaaacaatg cctccatctc aggtgctgag
     1981 ggtgggtgtc aagctgaagt tggttcagcc tctgctatga gtgctgccgc cttgactctg
     2041 gctgcaggtg gaacacctta tcaggccagt caagctattg cctttgtcat taaaaatatg
     2101 ctaggcctca tctgtgaccc tgttgcaggt ttggtcgaag ttccctgtgt caaacgtaat
     2161 gccatgggag ctagctttgc tttcatcgca gcagacatgg ccttggcagg tatcgaatct
     2221 aaaatccctg tggatgaagt gatcgatgcc atgtaccaag taggagcaag catgccaact
     2281 gcctttcgtg aaacagctga aggtggactc gctaccaccc ctactggtcg tcgcctccaa
     2341 aaagaaattt tcggagaata agcttatcaa ataggagaaa ccatgacctc tatcacagcg
     2401 atttttttcg atttggatgg aaccctcgtt gatagttcta tcgggattca caatgccttt
     2461 acctatacct ttaaagagct gggggtgcct agccctgatg ccaaaactat tcgtggtttt
     2521 atgggaccac ctctcgaaag tagttttgcg acctgcctgt ccaaagacca aatttctgaa
     2581 gccgtgcaga tatatcgttc ttactataag gcaaaaggca tctatgaagc tcaactcttt
     2641 cctcagatta tagacttgct tgaggagtta tcgagcagtt atccactcta catcaccacg
     2701 acaaaggata catctactgc tcaagacatg gcaaaaaact tggaaatcca tcatttcttt
     2761 gatggcattt atggttctag ccctgaagca ccccataagg cagatgtcat tcaccaagcc
     2821 ttgcagacac atcaactagc accagaacaa gccatcatca tcggagatac caagtttgat
     2881 atgctgggag ctcgagaaac aggtattcag aaattggcca tcacttgggg atttggagag
     2941 caagcagatc tactaaacta tcaacctgat tatatcgctc acaaaccctt agaagttttg
     3001 gcgtattttc aatagcatag actgggtaac aattccattt cagaagaaaa tgaagtaata
     3061 ctcaatgaaa atcaaagagc aaactaggaa actagctgcg ggctgctcaa aacactgttt
     3121 taaggttgca gatagaactg acgaagtcag taacatatac atacggcaag gcgacgttga
     3181 cgtggtttga agagattttc gaagagtata agtctctaca taataaaacg catattacca
     3241 aggttgtgta acttgatact atgcgttttt cttttttatt caatgtgggt tgtttgatta
     3301 gcaaaggcga taatagcttg cttcaactca tctccactga gagtgtggaa ctctccaatc
     3361 ttttgattga tggattctaa aggcatgaca ttaaccttac caacgaaaat cttatccata
     3421 acttgattat caacgagttc ggttgatacc aagagttctt cgtagagttt ttcacctggg
     3481 cggattccaa cttcaacgat tggaatttca ctttcagtgt ggccacttag aagcaccatc
     3541 ttcttggcca agtcataaat cttgactggt ttgcccatat caaggataaa gacttcccca
     3601 tctttggcat aagcaccagc atggataacc agacggctag cttctggaat ggtcataaag
     3661 taacgggtca tgcggaagtc tgtcaccgtt acaggcccac cttcagcaat ctgacgttca
     3721 aagactggaa tgacactacc acggctacca agaacattcc caaaacgaac tgcacagtag
     3781 gttgattggc tacgttggtt aaagccagtg acaatcaact ccgccacgcg cttggttgct
     3841 cccataacat ttggtggatt aactgcctta tctgtcgaaa tcataaccat cttagacact
     3901 ttagcttcat caacagcctt agcaacattg taagttccac ggatattgtt tttgaaggct
     3961 tcttttggat tgcgctccat cataggaaca tgcttgtggg ctgccgcatg ataaacaata
     4021 gcaggtttgt actgctcaaa gacttgcaac aaacgatcat agtcttgaat gtccgcaatc
     4081 acaggtacat aatcaatccc ttggaactta cgaatcaatt catgataaac aaggtagatt
     4141 gagttttccc catgaccgag caagacaatg cgttcaggat tgaagcgact aacttgacga
     4201 cagatttcag aaccgattga acctccagct cctgtgacta agatggtctt acctgtcagt
     4261 tctgcaccca gacgcgattc gtcaagacgg atttcctgac gacccaaaag gtccgtaata
     4321 tcaatttttt ggaagccagt acctgcttgg tgaaggccct gaacaacagt ttcaacctta
     4381 ggcatcttgt aacatttgac acccagctta ttacacatct gcaagatacg ctcatattct
     4441 gacggatcca gcgacggaat cgcaacgatg acacgctcga tttgatggcg tttggctaat
     4501 tcaggcagat tgtcataaga gcccaaaaca ggaataccac caagtttttg accctttttc
     4561 ttagaatcct tatccaaaat accgaccagt tctaattcac tggttggatg ttggtaacta
     4621 tccataaaaa gagccccacc atcaccggca ccaatcaaga aggtccgacg gtgttctcca
     4681 tcaccactac cttttttgcg tctggagtag attaactgcc aagtaatccg tggcaataaa
     4741 atcaagaagg tactcaacaa gataaagaga atgataaaac ggatggagaa gagtggcaag
     4801 aaggcataac agatactata tgacaagaca ctgctagcag tcacaccaaa aaagattttc
     4861 atgaaatccg taatcttgct gtaacgacta atgctcgcgt tcaaccccca aaaaccaatc
     4921 atcaattgat agaacaggaa ggccaaactc gtatagataa tgtagtcaac aggtgctgga
     4981 ttaatcagcc cataaaataa aatataagat acaatgatgg aaaccaccat actgaaaata
     5041 tcaaatattc cccagaaaac ctgcttttgt tgtttattta aaatttccac cagatcaatc
     5101 acataatctg ttagtttttt attcatagaa atctactcct ccttaaaaga gttttactat
     5161 attgttatta tagcatattt ttatttattt ggcttatttt atccaaataa attattgttc
     5221 tcttgtactc cttcttccat ttaaatcctc taattaaacc tacaatcgtc ccaaagccat
     5281 aagcaaagtg aatggaaaat aaaagaaagg gcatcacaat tagaaatcca tttttatgtt
     5341 ttaataaagt cagcaaagtg agtagtgaca aaagtagaaa ataggcacct aatagtaaag
     5401 ttatgaatac gaatgtgatc ggtaacaatg ctagactaaa cacaagactc aaaacaaata
     5461 aacaaggaac atagtgaaat aatgataaac acttaaactg aacatgactt gtcaagccaa
     5521 tccacaaacc atttaaatac ttttgatgca gcattttctt gaatgttggt cgaatatact
     5581 gataagatag aatacttggg ctatagcgga ttttataacc atattctcga attctataat
     5641 gaatatcatt atcttcagtt cggccaagtt gctcatttac taaaccaacc ttctggaaaa
     5701 cctctcgttt atacatccca tgaaaaatag aagaaacata tctatcctca gaactatttc
     5761 gataattggc aatgctactg ccaaacatat tttcctcaac aagatgcaag gtctctgccc
     5821 attttccttt tccttcgaca atcgtcggtc taggcccccc acagacaaat tcaccttgtt
     5881 gaataatagc cacattgttc attacaaaac tctcagtaac ttttgaatga gcatcaattt
     5941 ttaaaataag gtcccctaca gaatgtttaa ctcccaggtt aaaaccacta gcttgatttt
     6001 tcttaggatt gttatacaat ctaattgagt taaactctgt atcttccttt ataaattgct
     6061 gaatgatagc tgtggtccca tctgtggaca tagcatttat aaatagaatt tcaatattct
     6121 ctttaggata ggtttgattt tttaagtctt caattagacc aggcagatat ttttcttcat
     6181 tgtatgcact gattacaatg gatacgagaa gactttcaac attttgagtc actactactc
     6241 tcctgaattt ttccttccac cattctatca taattttcaa gactttccca tttttatctt
     6301 gaaagccaga aaccttactt gacattatag tgaaaaagcc ttaaaataag ctgttattaa
     6361 aatcagctag aagaggtatt atatgaaaaa gcaatcactc ttttttgttc caggtattat
     6421 cctgattggt gtttccttgc gaactccttt tactgtttta cccattattt tgggaaatat
     6481 ttcgcaaggt ctggaggtag aagttagttc gcttggtgtc ttgaccagcc tgcctctcct
     6541 tatgtttacc ctcttttcac cattgtctac ccaactggct cagaaaatcg gcttggagca
     6601 tctcttcacc tacagcctct tcttcttgac catcggctca cttattcgac taatcaatct
     6661 gcccctgctc tatctaggaa ccttgatggt tggggcaagt gtcgcagtca tcaatgtcct
     6721 gcttcctagt cttatccaag ccaatcaacc aaagaaaatt ggttttctga ccaccttata
     6781 tgtaacgtct atggggattg caacggctct ggcttcctat ctagctgtgc ccattacaca
     6841 agccagttct tggaaaggac ttatcctcct cctcacgtta ctctgtctag caactttttt
     6901 ggtctggctc ccaaatcacc gctataatca tagactagct ccacaaacca aacaaaaaag
     6961 tcaaataaag gtcatgcgta ataaacaggt ttgggcaatt attatctttt caggttttca
     7021 atccttgatc ttttacaccg ccatgacctg gttacctacc atgtctatcc atgcaggtct
     7081 atccagtcac gaagctggct tgctgacttc tatcttatct ctgattagca ttcctttttc
     7141 aatgaccatc ccaagcctga caaccagttt atctactcgc aaccgtcagc tcatgctcac
     7201 tctggtttca ctagctggtg tggtcggcat ttccatgctc tttttcccaa tcaataattt
     7261 catttactgg cttgccatcc atctcctcat cggaaccgca accagcgccc tcttccctta
     7321 tctcatggtc aacttttcac tcaagacaag cgcccctgaa aagacagccc aattgtccgg
     7381 cctatctcaa acaggaggct atatcctagc agcctttggg ccaaccctct ttggttacag
     7441 ttttgaccta ttccactctt gggtaccagc tgtagctgcc ctcttgctca tcgatatcct
     7501 gatgactgtg gccctcttta cagtggacag agcggataag atcctttaaa cttctagttt
     7561 tagctagaag ttttttatat ataaaaattt tacacatttc tcttgacagg gctttctttt
     7621 agatgtacaa tgtatgtgta gaaaaattat atataaaaat cttacacatt agaaaaggag
     7681 gtttcccatg tactttccaa catcctctgc cttgattgaa tttctcatct tggctgtact
     7741 ggagcagggt gattcttatg gttatgagat tagccaaacc attaagctga tcgctaatat
     7801 caaagaatcc acactctatc ccattctcaa aaaattggaa ggcaatagct ttctgacaac
     7861 ctattctaga gagttccaag gtcgcatgcg caaatactac tccttgacaa acggtggtat
     7921 agagcagctc ttgaccctaa aagatgaatg gacactctat acagacacca tcaatggcat
     7981 catagaaggg agtatccgcc atgacaagaa ctgaatacct gactcagcta gaactctatc
     8041 tcaagaaact acctgaagct gaccgtatcg aagccatgga ctatttcaga gagctctttg
     8101 acgatgctgg agtcgaagga gaagaagaac tcatcgctag tttgggaact cccaaagaag
     8161 tggcccacga agttctatcc aatcttctcg ataaaaaaat caatgaagca cccgctcaaa
     8221 aaaataaccg acaaatttta catatcgcct tgttagccct ccttgcagca cctatcggca
     8281 ttcctctggg aatcgccatc ctcgtgaccc tgttcgcaat ccttgtagcc gctttgactg
     8341 tcattctggc tttctttgca gtttccatac tgggtatcat cggcggattc ctatttttag
     8401 ttgaaagttt cactgtcctc gcccaagcca aatcagcctt tatcttgatt tttggttctg
     8461 gtttactggc tatcggtgct tcttcgctag ttttacttgg catttcctat gtagctcgct
     8521 tcttcggtct actcattgtt cgtctggtac aatttgttct taaaaaagga aagagaggta
     8581 atcagcatgc gtaaatggac aaaaggattt ctcatctttg gtgtggtgac taccgttatc
     8641 ggctttattc tgctttttgt aggtatccaa tctgacggga ttaagagcct actttccatg
     8701 tccaaagaac ctgtctatga tagccgtacg gaaaagctaa cctttggcaa ggaagtcgaa
     8761 aacctagaaa ttactctcca ccaacacacg ctcaccatca cagactcttt cgatgatcaa
     8821 atccacattt cttaccatcc atctctttct gctcaccatg atcttatcac caatcagaac
     8881 gatagaactc tgagtctcac tgataagaaa ctgtctgaaa ctccgtttct ctcttctgga
     8941 attggtggga ttcttcatat cgcaagtagc tactctagtc gttttgaaga agttattctc
     9001 cgactaccaa aagggagaac tctaaaaggg atcaacatct cagccaatcg cggacaaacc
     9061 accatcataa atgctagcct tgaaaatgcg accctcaata caaacagcta tatcctccga
     9121 attgaaggaa gtcgtatcaa aaacagtaaa ctcacaacgc ccaatatcgt taatatcttt
     9181 gatacagttc ttacagatag tcagctagag tcaacagaga atcacttcca cgctgaaaat
     9241 atccaagtcc atggtaaggt tgaactgact gccaaagatt atctcagaat catcctagac
     9301 cagaaagaaa gccaacgaat taactgggac atctcaagca actatggttc tatcttccaa
     9361 ttcacaagag aaaagcctga atcaagaggt acggaattaa gcaaccctta caaaactgaa
     9421 aaaaccgatg tcaaggatca actcattgcg agatctgatg ataatattga tctaatatcc
     9481 acaccaagca gacgttgaca aaaacgctta catctgctac tatggaagca tatttatcta
     9541 actaaaaagg aggttctacc atgaaacaag aatggtttga aagtaatgat tttgtaaaaa
     9601 caacaagcaa gaacaagcct gaagagcaag ctcaagaggt tgcagacaag gctgaagaaa
     9661 cgatagccga tctcgataca ccaattggaa aaaatactca agtagaggag gaagtctctc
     9721 aagctgaagt cgaactggaa agccagcaag aagagaaaat tgaaactcct gaaggcggtg
     9781 aagcgagaac agaaatagaa gaaaagaagg catctaattc tactgaagaa gagccagacc
     9841 tttctaaaga aacagaaaaa gtcactatag ctgaagagag ccaagaagct cttcctcagc
     9901 aaaaagcaac cacgaaagag ccacttctta tcagtaaatc tttagaaagt ccttatatcc
     9961 ccgaccaagc tccaaaatct agggataaat ggaaagagca agtgcttgat ttttggtctt
    10021 ggctagtgga agcgatcaaa tctcctacaa gtaagttgga aacaagtatc acacacagtt
    10081 acacagcctt tctcttgctc attctgtttt ctgcatcttc ctttttcttt agtatctatc
    10141 acatcaaaca tgcttactat ggacatatag caagcattaa cagtcgcttc cctgagcagc
    10201 tagctccttt aactcttttt tctatcatct ctatcctagt agcgacaaca ctcttcttct
    10261 tttcattcct cttgggtagt ttcgttgtga gacgatttat ccaccaggaa aaggactgga
    10321 cgctagacaa ggttctccaa caatatagtc aactcttggc aattccaatc ttcctcactg
    10381 ctattgctag tttctttgct ttctttgata gcctacgatt tacagccctc ttgtgtgtga
    10441 ttagcattgg aatcattctg cttgccagtc tccatatcat tacaagacca agtcaagcaa
    10501 gtgaaaccga ctccttctat caattattct tgtctgtcct tgtgaacgga gttattatcc
    10561 tcctcttctt tgtagctgaa gtggcactga ttggagatta tcttcgtatc ttggcctttc
    10621 tttaaacttc atactcttcg aaaatcaaat tcaaaccacg tcagcttcgc cttaccgtac
    10681 tcaagtacag cctgcggcta gcttcctagt ttgctctttg attttcattg agtagcaatc
    10741 ctgtcatcct tggcaggatt ttttctatgt caaaaaagca agtcgattga cctgcttctg
    10801 ctttactttt cttgtgctaa tgttttaaaa tctttgtcta atatgggttg catttctatt
    10861 tgattggcgt ctagttggtg gtaaaaagat gggggtaata cctctaagaa ttttgcatag
    10921 tccaagcggg caatggcttc atagtcttct ggtttagagc cgtctcctgt gatttgaacc
    10981 aagtcaatct cccactggac ttccttatcc accaattgct caatataggc tgcaggaaca
    11041 aacggttctc tcggtaaaac tgtcttgact ccttgagcta gatggtaaac gccatgcact
    11101 tttccttctc catcctgata gaaggaaact ctcgcaaagt aggcatctgt ctcttgaacc
    11161 gcacgcacac gcgcttcaaa ctgagccaag ccatctgcct ctaaaaagct tttcaagttc
    11221 tcacgactaa agaaaatagg attaaaaatt ccttggcaaa tcgtaaaacg agctacaggg
    11281 tctgctagat aggcttgaat acttgcttgg aaataagctt caaaatcaaa accatctagc
    11341 ccttcaatat cagtccctgt ataagcaagc aaagcatcta aaaatgactt gataatctgc
    11401 cagtctgtct ttgttagtag gtcaggaaga tcgacacggt aagccttttg accatcagca
    11461 taactgacct taaaaagaaa ttgtgattgc cccactatcg cacactcaat atactcgaga
    11521 cgattaagag gctgacggag atagactaca tcatagctat gtgactccaa accgtctagc
    11581 aaggccaaga tcgacttggc attcaaaatc tcttgttctc ctaaaatgct ctgtttattt
    11641 ggaataaaaa atgttttcgc cataactgga ctcctttgaa atcgtttaca tacagtatac
    11701 cttatttttc tgaaagatac aaaaacaaac tttatattct tcgaaaatct cttcaaaccg
    11761 cgtcagcttc gccttgccgt agatatatgt aactgacttc gtcagtctta tctacaacct
    11821 caaagcagtg ctttgagcag cctgcagcta gcttcctagt ttgctctttg attttcattg
    11881 agtattagat ttttgagtac aaagcataga aaaacagccc ctgaggactg tttgatctta
    11941 tacagtagct gcttgatcca agctttcacc gatagcggct aggcgctcga tcacttcagc
    12001 ttgtgtcaat tcattttttg aaacatagcg gttacgtggg tgaacacggc actcgtgtga
    12061 gcatccacga aggtacttgt cttcattttc ttctgatgtc aagatacgac ggttacagaa
    12121 gggatttcca cagttgacat aacgttcaca tggcgttcca tcaaaccagt ctttccctac
    12181 gatagttggg ttgacatggt tgacatcaac ggcaatacgc tcgtcaaaga cgtacatttt
    12241 cccatcccaa agctcacctt gaacttctgg gtctttaccg taagttgcga ttcctccgtg
    12301 caattggcca acatctttgt aaccttcacg aaccatccag cctgagaatt tctcacagcg
    12361 aacaccacct gtacagtaaa ccacgacacg cttgtccatg aatttttctt tgttgtcacg
    12421 gacccattgt ggtaactcac ggaagttgcg aatatctggg cgaatagccc cacggaaatg
    12481 tcctaggtcg tactcataat cgttacgtgt gtcaaggaca acggtatctt tatcaagaag
    12541 cgcttctttg aactcttttg gagacaagta agcacctgtt gtttcaagtg ggttgatgtc
    12601 attgtcaaag tcgttgtctt ccaaaccaag gtggacaatt tctttcttgt agcgaacaaa
    12661 catcttcttg aaggcttgtt cattttcttc gtcaatcttg aaccagagat cttccattcc
    12721 tggaaggctg tgaacgtagt ccatgtattt ttgagttgtt tcatagtcac ctgaaactgt
    12781 tccgttaatt ccctcgtcag cgactaggat acggccttta agaccgattg atttacagaa
    12841 agccaagtgg tctgcagcaa attgctctgc attttcaatt ggagtataaa ggtagtaaag
    12901 taagacacga atatcttttg ccataagatt tgttctcttt tctattctta aattttctaa
    12961 attttttatt tatccatact agtatacctg cttgagaaaa cgaatgcaat ttatttgact
    13021 ggaaattgta gagggttctc gaaatttcct gaatggttaa aataaggaca agagaaaaca
    13081 tggatatcta tatccttgtg ccaaaaaaac cactgccctc cccagaccaa cctgaagaaa
    13141 gcagtgattc ttattttagg agttaggaat gaatacacga aatcaattta gctgattatt
    13201 ttttgttttt caagaattca tcgtattgtt tttgcatttc gttcaatact ttttcgtagg
    13261 caccttcaga tttcaatttt tccatcaatt ctggaatcgc tttatctggg tctacagtac
    13321 cagtgttgat agctgtatca aattgttgca ttgtgttagc aatagctgag atttcagatt
    13381 tcacattgtc agtattgaag ataaatccaa gcgctggaga ttctttagct tctgccaatt
    13441 ctttcttaga attttcgatt tgttggtctg taacgttttc attgatgtaa aggatccagt
    13501 tgttaccagt gttccatcca cccatgtgag tgtttccttt gtagccatca agaacgcgaa
    13561 cacggttttc tttaccttca attttttccc agttcttgcc ttctggaccg taaacaagac
    13621 cgttcaagag ttctgggttc gtattcaaga ggttcaagat ttccattgat ttttctttgt
    13681 tcttagagtt gtttgagatg acaaagttag caacttgtgt tgtttggttt ttcttgatga
    13741 agttagtaat tggtttgatt tggatatctt tgttggcaac acgtgaaagc aagctgttac
    13801 cgtagtcagc tggtcctact gtttcttcac gaacgaacca agtatcttgt tgaaggtcaa
    13861 atgaagtatc gcttgttgcg acatcttttg gaatgtagcc agcttcatag aatttgtgaa
    13921 gagtcttcaa gtgttctttg aaacgaggca cttcgtaacg gtttacaact ttagtagtat
    13981 cgccttcaag atcaataacg aatggaagcc cgtttgctac tgggtagtca aagttatcag
    14041 atgggatgaa aactttacca atagcaaatg gtactacgtc tggagctttt tctttaattt
    14101 gtttcaagac tggctcaaga gtttcgtaag aagtaacacc tgaaatatcg ataccatatt
    14161 tggcaaggag agttccgttg aaggcaaagt tttgagatga tgcaacgttg gctgcaactg
    14221 gaacagcgta aattttaccg tttacagtat tacccttgat gtaagctggg tcaagtgcct
    14281 tgtaaaggtc tttaccttct tttttgtaca attctgtcaa gtcagcataa gcaccttttt
    14341 gagcatttac aatatagtta tctgcaaagg cgatatcata gttttcacca gatgatgtga
    14401 taactgacat tttcttacca tagtcacccc agccaaggta ttggatatcc aatttggcac
    14461 caactttttc ttcgatgatt ttgttggcat ttgctaacaa ttcatccaag ttatctggtt
    14521 tgtcaccgat ttggtacatt ttgataacag gtttgtcacc tgaatcagca gcttttttgc
    14581 tgttacctgt caaatttcca caagcagcaa gacctgcagc caaagcgact acactagcag
    14641 atgcaaaagc atattttttc cagtttttca tgataaaaac tccttttttt atttttaaac
    14701 ttataaacaa tgtaatgatc ttatactcaa tgaaaatcaa agagcaaact agaaaactag
    14761 ccgcaggctg ctcaaagcac tgctttgagg ttgtagataa gactgacgaa gtcagttaca
    14821 tatatctacg gcaaggcgac gttgacgcgg tttgaatttg attttcgaag agtattaact
    14881 tcacacaagg gaagttggga actgagaaat gttatttctc aataagcact attctttcac
    14941 accaccgata gtcaaacctt ttacaaagta gcgttggaag aatggataca aaatcgcgat
    15001 tggaagggtt gctaccacaa ccatggccat acgacctgtt tctttcggta gagcaactcc
    15061 cagttgacca gtcaagccga ccgctttggc aatgtagtcc atattttgtt ggatttgcat
    15121 gagcaaatat tgcaatggat acaagttgtc actcttgatg taaagaaggg cgttgaacca
    15181 gtcattccag aaaccaagag ctgtcaaaag cgtgatggtt gcgatacctg gtagtgacaa
    15241 tggcaaacag atttggaaga aaatccgggc ctcactggca ccatcgatac gagccgattc
    15301 gagaatggct tctggaatgg tcttcttgaa gaaggaacgc atcaagatga tattgaatgg
    15361 tgagagaagc attggaacaa tcaaggccca aacagtgtca ccaagctgaa gtacacgggt
    15421 caccatgata taacctggta ccaaaccagc gttgaacaac atactgagaa ggacgaagat
    15481 ggtaaaaaat ctgcgatact taaaggttgt ccgtgaaata gcgtaggcat aggttgttgt
    15541 gataaagaca tttgtcaatg tcccaactac ggttacaaag acagagatga agagggcttg
    15601 taggatttta tccttaaact gtgccaaaaa ctcaaaaccg tctaagccaa attgggatgg
    15661 gaagaagcta tagccgtatt ggaggaggct tttctcgtct gtcactgaaa taatgataac
    15721 gaatacaaaa ggtaggatac aagagagggc aatcaaaccc gaaatgatac tgaagaagat
    15781 atctgctttc ttactgaagg agtgaatgcc gacattatca attttttctt ttttaatttt
    15841 cttttttgcc atattctcct cctttctaga acaaagctga gtttggatcg actcgtcttg
    15901 caagcaagtt tgataggata accagaatca aaccaacaac ggattggtaa agaccggctg
    15961 ctgcagccat accgatatct gctgtctgag tcaaaccatt aaagacatat acgtccaaaa
    16021 cgttggttac attgtaaagc tgaccagcat tgtgtgggat ttgatagaag agaccgaagt
    16081 ctgcgcggaa gatatttccg actgcaagga tggtcaatac agttacaagc ggagtcaact
    16141 gaggaatggt tacgttgcga atacgttgcc acttgctagc tccgtccact gtcgctgctt
    16201 cgtagtaggt tggatcaatt cccatgatcg tcgcatagta catgacactg ctatatccaa
    16261 agcctttcca aatacctagg aaaagtagga gatagggcca gatgcccagg tcagcgtaaa
    16321 aattgacttc tttgagacca agactttcca atagatgatt gaacacccct ttatcaatat
    16381 ttaggaaggc atctgtaaag aaactgatga taacccaaga caagaagtaa gggaacaaca
    16441 tagaagtttg gaaaatcttc accattctct tagaacggag ctcgctgagg ataatggcaa
    16501 tccctacaga tacaactaaa cctagaaaga taaagccaag attgtagagg acagtatttc
    16561 gtgtgataat aaaggcgtct cttgaactaa ataagaatct gaaattatcg agtccgaccc
    16621 atttactatt tatgatacta tctatgaaac cattactggt catgtggtag tctttgaagg
    16681 caaccacgtt cccaaatact ggaatgtaaa agaatagaat caaccagagt gcccctggca
    16741 aaaccatcaa gagaaagatc cagttgtctc tcaatgtttt tgaaaacttt ttcataattt
    16801 cctccctttt tattttgata tccatctaaa aattcttttt tagacttttg ataacgatta
    16861 cattattagt atactcctat ttgcaggtta ggttaaactc ctaattatag aaaaaactcc
    16921 acaaattatg tagcagattt aaaactttat caccactatc aaacaaatgt cctaaatcaa
    16981 ttgtttattt tatctctatt agcccagtga tggcgtcact ctgttataag catccaacaa
    17041 cggggtatac tgaaaaatct ccagactagg gaactcagcg atagttccta atctggagat
    17101 ttttaatatg ttattaggcg tttgctttca acttagcaat aacctcttta agattatcaa
    17161 tcaactctgc ttcagtatgc tcagagcctt tttcatctgc caagaacaaa actgcttttt
    17221 gaagttcttc ttgagagttt tcaaggacat ccttatctac tgtttcaagg tttgagtctg
    17281 cttactaata ctagactaaa atcaaaaagc attatataat agtaatatga aatcaactaa
    17341 agaagaaatc caaaccatca aaacactttt aaaagactct cgtacagcta aatatcataa
    17401 acgccttcaa atcgttctat agtaaaatga aacaagaaca agacaaatcg atttctaaca
    17461 atgttttaga agtagaggtg tattattcta gtttcaatcc attatatttc gtctgatggg
    17521 caaatcttat aaagagatta tagaactttt atagtagttt gaaataagat gtgaacaact
    17581 ctatcaggaa agtcaaatta atttatagaa atattttagc agccaaggtg tactgttata
    17641 gattcaatac actatacttg gtggtttagc tctcctgttt tctcttttgg ctttaaccag
    17701 ccataaatgg tattacgtga gatttggaaa acgtgtgatg cttctgttat actacctgtt
    17761 cgctcacaat aagagagaac ttttttacga aaatctattg aatatgccat aaaaagatta
    17821 taccacattg tgtactattt ttggttcatt ttactatatc actttggact atatcggtct
    17881 agttatgtct aaacgattat agctggatac taagagaaat caaaaaaagc actctaggat
    17941 agaggcctaa agtgcttagt ttcaaggctt tacagcctat catatttaat aaaatattac
    18001 aacattttgt tgtagaattc aacgacaagt gcttcgttga tttctgggtt gatttcgtcg
    18061 cgttctggca agcgagtcaa tgaaccttcc aatttttcag cgtcgaatga tacgaatgct
    18121 ggacgtccaa gagtagcttc tactgcttca aggattgctg gaactttcaa tgatttttca
    18181 cgaactgaga tcacttgacc tggagttacg cggtatgatg ggatatcaac gcgtttcccg
    18241 tcaacaagga tgtgaccgtg gtttacgaat tgacgagctt gacgacgagt agtcgcgaga
    18301 ccaagacggt aaacaacgtt atccaaacga cgttccaaaa gaagcataaa gttgaaacct
    18361 aggattccgc ctttgatttt tgtagcttgt acgaacaagt tacggaattg tttttcacct
    18421 acaccgtaag tgaaacgaag tttttgtttt tcagccaatt gcaaaccgta ttctgacaat
    18481 ttagaacggt tgtttggtcc gtgttgtcct ggtacgtagt tacgacgtgc caattcttta
    18541 cctgtacctg taagtgaaag gccaaggcga cgagcttgtt tccaagatgg tcctgtataa
    18601 cgtgacatat gaatgtcctc ctgatataaa taatatttcg gtggaaatag tcacttagaa
    18661 agccctgatt cgtgcagatg cccttcgcct aaacagccaa ggttacttgt cataagacac
    18721 ctgttgacga gcttcatgct ttcctgctga tatttcacac aaaatctatt ctaccatgaa
    18781 tagctggatt tgtaaagggg ttttaggctt tattttcact accagagagg ttgagaacga
    18841 gggtaaaggt acttcctaga ccgtactggc tgctgactgt gatttcccca cccaattgat
    18901 gggccaattc acgcgcaatc gcaagtccta atccatgacc acctgtcttc atgttacgcg
    18961 aagtttcgac acgataaagg cgtttgaaaa tattttccaa atcctctggg gcaataccct
    19021 gcccttcatc ggtcacactg attgaaagct ggtccttctc cagcttagcc accacttcca
    19081 gcttggttcc tggagcagaa tatttaaaag cgttatcgac cagattcacc aagatacgag
    19141 aaagcttagc ataatctccc tcaatccggg cagactctgg gattacctgc aagtggacat
    19201 ctcttctctc ctgctcaatc aaaaactgaa attcactcat gcactcaatt aagagcttgt
    19261 ccagaaaaat actgtcttta ctggtagttt ccacctgatt tctagctgtg tttagggtca
    19321 aaaaattcaa ctcctcaacc agtttattga gcctctccgt ctggcgtcca atggttgcta
    19381 gataatgagc ttgctccgac tccttgataa tcccatccaa aatcccttct accgtcgctt
    19441 ggatcgaagt gataggagtc ttaatatcat gcgacaactg agcaatcatc aagccctttt
    19501 ctcgttcgct ttcttccaag gaatcaaagc ttacctgcaa atcatgggac atctcattaa
    19561 aagtttgccc taattgctga aattctacag gaccttgaac ctccaaattt gaaggaaaat
    19621 ccttggccgc tacccgcttg gcatgctcct tgagtttgcc caacgacgta aagactggca
    19681 ataggagaaa gagactaatc ccagcaccga caaggctggc aacgatggtc atcccaagca
    19741 aaaagtaaat ctcgcctttc gcaatcagca ttttttgaac agcccaaaaa acaaccaaaa
    19801 tggttaagag ggttgaaata atatatccaa ccaaaatata actttttagt ttcatgtttg
    19861 tcctctcggt ttctctatct tatatcccaa cccccaaact gtcttaatag tgggcgtttg
    19921 gtcactacta tattttgcca gttcctgtcg aagagcatgg atatgcacat tcaaggtatt
    19981 ggtgtcatcc acgtagtctt ctttccagat cttttcatag aggtctgtct tggagaaaac
    20041 tcgctctgga ttgctagcta aaatccacag caattcaaat gatttaacag ttaaatccag
    20101 catttcttct cctatttgaa cttcatgact actatgattc atttttagat tgccaaggga
    20161 aatcagctct gtttcgcccc cacgatgaag gcggcgcaaa atattgtgga cacgcaaaac
    20221 cagctcacgt gggctaaaag gcttagcaat aaaatcatct gctcccaagc tcaggccgta
    20281 aatcttgtcc tgttcactgg tcttagcagt aataaatagg aaaggctgct ctggtgataa
    20341 gtattgaacc tcactgatta aatcataacc atccatccga ggcatcatga catctgtgat
    20401 aatcaaatca atcggttttt tcttgaacag ctctagcgct tccagtccat catgggctac
    20461 caagacctga taacctgcct gaattaagta tctctgatga atatctgtga tttctacctc
    20521 gtcatcaacg agtaaaattg tctttcccat ctgtctctcc tttgataaaa acagtgctat
    20581 actgctttaa gtataacact atttttattg ttttacgatg attttaatct gctattgaaa
    20641 gaaagtcctg attgctgatt gagttggtaa actagcctta gtcagcccac tatccatcat
    20701 ttatttcctt agctgattag ttttcttctt ttttgttttt caaacctaga ccaccgagta
    20761 aacctgcaag cgcaagccca aggaaaccaa tacttgccat tgatgtttga gtttcaccag
    20821 tatttggtag catagcttta tcatctgaca tcatcgtatc agacatcttg ttagcagaag
    20881 cagccatgtt ttcacctgcc atcgtgttgg tagaacttgc catggtatca gcaggcatgc
    20941 tatttgtagt acctggagct ggagtttcag gcttcatacc tgattttttc atctgatcat
    21001 ttgctgtgtc tgatgtttct ttaacattta t
//
LOCUS       DAVDZK010000038        20831 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVDZK010000038 DAVDZK010000000
VERSION     DAVDZK010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20831
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.039"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(139..2136)
                     /gene="metG"
                     /locus_tag="VUX16_001694"
     CDS             complement(139..2136)
                     /gene="metG"
                     /locus_tag="VUX16_001694"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET8124612.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPEGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEVVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2260..3519)
                     /locus_tag="VUX16_001695"
     CDS             complement(2260..3519)
                     /locus_tag="VUX16_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124613.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3521..4222)
                     /locus_tag="VUX16_001696"
     CDS             complement(3521..4222)
                     /locus_tag="VUX16_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124614.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4206..5405)
                     /locus_tag="VUX16_001697"
     CDS             complement(4206..5405)
                     /locus_tag="VUX16_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET8124615.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5691..7037
                     /gene="gor"
                     /locus_tag="VUX16_001698"
     CDS             5691..7037
                     /gene="gor"
                     /locus_tag="VUX16_001698"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET8124616.1"
                     /translation="MKEYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTVKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            7234..7770
                     /locus_tag="VUX16_001699"
     CDS             7234..7770
                     /locus_tag="VUX16_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET8124617.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7821..7907
                     /locus_tag="VUX16_001700"
                     /pseudo
     CDS             7821..7907
                     /locus_tag="VUX16_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7976..8191)
                     /locus_tag="VUX16_001701"
     CDS             complement(7976..8191)
                     /locus_tag="VUX16_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET8124618.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8289..8609
                     /locus_tag="VUX16_001702"
     CDS             8289..8609
                     /locus_tag="VUX16_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124619.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8639..8977)
                     /locus_tag="VUX16_001703"
     CDS             complement(8639..8977)
                     /locus_tag="VUX16_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124620.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVECATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8989..9708)
                     /gene="trmD"
                     /locus_tag="VUX16_001704"
     CDS             complement(8989..9708)
                     /gene="trmD"
                     /locus_tag="VUX16_001704"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET8124621.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9698..10216)
                     /gene="rimM"
                     /locus_tag="VUX16_001705"
     CDS             complement(9698..10216)
                     /gene="rimM"
                     /locus_tag="VUX16_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET8124622.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10262..11035)
                     /locus_tag="VUX16_001706"
     CDS             complement(10262..11035)
                     /locus_tag="VUX16_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET8124623.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAII"
     gene            complement(11612..11851)
                     /locus_tag="VUX16_001707"
     CDS             complement(11612..11851)
                     /locus_tag="VUX16_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET8124624.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(11871..12143)
                     /gene="rpsP"
                     /locus_tag="VUX16_001708"
     CDS             complement(11871..12143)
                     /gene="rpsP"
                     /locus_tag="VUX16_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET8124625.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            12313..12522
                     /locus_tag="VUX16_001709"
     CDS             12313..12522
                     /locus_tag="VUX16_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124626.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            13001..13222
                     /locus_tag="VUX16_001710"
     CDS             13001..13222
                     /locus_tag="VUX16_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124627.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            13305..14108
                     /locus_tag="VUX16_001711"
     CDS             13305..14108
                     /locus_tag="VUX16_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET8124628.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITVDSIEVVKDYDFKS"
     gene            complement(14164..15705)
                     /locus_tag="VUX16_001712"
     CDS             complement(14164..15705)
                     /locus_tag="VUX16_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET8124629.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERHQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKCALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(15707..16189)
                     /locus_tag="VUX16_001713"
     CDS             complement(15707..16189)
                     /locus_tag="VUX16_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET8124630.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(16189..17274)
                     /gene="rlmN"
                     /locus_tag="VUX16_001714"
     CDS             complement(16189..17274)
                     /gene="rlmN"
                     /locus_tag="VUX16_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET8124631.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRTDQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHIMVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(17295..17825)
                     /locus_tag="VUX16_001715"
     CDS             complement(17295..17825)
                     /locus_tag="VUX16_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET8124632.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(17981..18586)
                     /locus_tag="VUX16_001716"
     CDS             complement(17981..18586)
                     /locus_tag="VUX16_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET8124633.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(18759..19796)
                     /locus_tag="VUX16_001717"
     CDS             complement(18759..19796)
                     /locus_tag="VUX16_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET8124634.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(19830..20765)
                     /locus_tag="VUX16_001718"
     CDS             complement(19830..20765)
                     /locus_tag="VUX16_001718"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET8124635.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
BASE COUNT         6068 a         4539 c         3826 g         6398 t
ORIGIN      
        1 agctgacttc gtcagttcta tctacaacct caaagcagtg ctttgatcaa cccgcggcta
       61 gcttcctagt ttgctctttg attttcattg agtataaata aaaaaaacag aactagtctg
      121 aactagtcct atctactttt acccaatcac acttccattt ggtacagctg gatcaactgt
      181 gagaagggtt aatttgccat catgttcagc tgagagaatc ataccctggc tgacatattt
      241 tttcatcatt ttacgtggtt tgaggttagc aacgatttga actttcttgc cgaccaattc
      301 ttgttcattt ggatagtatt ttgcaattcc tgaaagaatc tgacgatctt ctccatcacc
      361 agcatccaag cggaattgaa gcaacttatc tgaaccttcc actttagaca cttctttgac
      421 ttctgcgaca cggatttcaa ccttgtcaaa gtcttcaaac ttgatttcat ccttgtttag
      481 tttgagctca acttcgtccg gattccattc tttttcgact gctggtttat tgccttccat
      541 ttgttccttg atataggcga tttcttcttc catatttaga cgtggaaaga taggtgttcc
      601 tttggcaact acagtcacat ctgctgggaa gtcagccaaa ctcaagtttt caagactaga
      661 aacttcttcc aaaccaagtt gagtcaaaac tgcacgacta gtttccatca taaatggttc
      721 aatcaagtga gcaactacac gaatgctggc tgccaagtgg ctcatgacac ttgccaattg
      781 gtcacgaaga gcttcatcct tggccaagac ccatggtgcg gtctcatcga tgtatttatt
      841 ggtacgagag atcagagtcc agactgcttc aagcgcacgt ggatagtcaa ctacttccat
      901 gtgtgtatgg aagtctgcga ttgattgttc tgcaacctca gcaagaacat gatcaaattc
      961 agtcacacct tctacatagg cagggatttg tccatcaaag tacttattaa tcatggaaac
     1021 cgtacggtta aggaggttcc caaggtcatt agccaattca tagttgatac ggccgacata
     1081 gtcttcagga gtaaaggttc cgtctgaacc aactggaagg ttacgcatga ggtagtaacg
     1141 aagtggatct agtccataac gctctaccaa catttcaggg taaacgacat tcccttttga
     1201 cttagacatt tttccgtctt tcatgacaaa ccaaccatgg gcaatcaaac gatcaggtaa
     1261 tttaacatcc aacatcataa gaaggattgg ccagtagata gagtggaagc gaaggatgtc
     1321 ttttcctacc atatggaaga ctgttccatt ccagaacttg tcaaagttac catgttcgtc
     1381 ttgagcgtag ccaagagctg tcgcatagtt aagaagggca tcaatccaaa cgtagacaac
     1441 gtgttttgga tttgatggga caggcactcc ccatgtaaag gttgtacgag ataccgccaa
     1501 atcttccaaa cctggctcga tgaagttgcg tagcatttca ttaaggcgac cctctggcgt
     1561 gataaattca ggatgagctt tgaaaaattc gaccaaacgg tcttggtatt tgctaaggcg
     1621 aaggaagtat gattcttcag aaacccattc aacctcatga cctgatggag caataccacc
     1681 agtcacattt ccagcttcat cacggaaaac ttctgccagc tggctttctg taaagaattc
     1741 ttcgtctgat actgaatacc aaccagagta ttcacccaag tagatatcat cttgagcaag
     1801 taagcgttca aagacctgtg cgacaacttt ttcatggtag tcatcggttg tacggataaa
     1861 tttatcgtat gagatatcta gtaattgcca gagttcttta actccaaccg ccattccatc
     1921 aacataggct tgaggtgtaa taccagcttc ttccgctttc tgctggattt tctgaccatg
     1981 ttcatcaaga cctgtcagat aaaatacatc gtagcccatc aggcgtttgt aacgtgctag
     2041 gacatcacat gcgatagttg tgtaggcaga accgatatga agtttcccag atggatagta
     2101 aatcggcgtt gtaatataaa aatttttttc agacataatt tttcctttcc aggcaaatga
     2161 aacctgtttt tctaacactt cattatatca catttttaat gaatttcgat agggaaatcc
     2221 atacaaaaac aagatagacg agtgtccatc ttgttgatct cattcataac gaagggcttc
     2281 aattggatca agtttcgatg ccttgttggc tggcaagact ccaaaaatca taccaacact
     2341 agccgaaact gcaagactaa atagggcaac tgggattgat actccaactt ctataccttc
     2401 tattaaacct tgcagtaaca aacctgctaa ggcagttaaa ccacttgcaa ttgtcaagcc
     2461 aattaagcca cctaacaagg tcaaaatcat ggattcaatc aaaaactgaa ttaaaatatt
     2521 ggcacgtgtt gcacccaaag ccttacgaag accaatctca cgagtgcgct ctgtcaccga
     2581 aaccagcatg atgttcatga caccagttcc tccaacaaag agagaaatcc ctgcgatgga
     2641 actaataatc gtcgtcataa aactaaacga ttgttgaatt tctgcaaata caacggactc
     2701 atctgccacc tggtattctc cctgttgtaa gcctgcaagc tctgtcattt ttcgtgccag
     2761 ttctggaccc agagttgggg ttaaactggt atcattcact cgaaagacaa tattagctat
     2821 ttcatctaca ttaaaattcg cagcaaggga gatattggta gtaataggca agccaccaaa
     2881 cccatatatt tttgatcttt tagcctccgg actagtataa accccaatga cccggtaact
     2941 aaatccattg acttctacaa ccttgttaat agcctcttga ggagattcaa ataaactaat
     3001 ggacaattcc tcatctagca aaatgacact tgcaaactct ttgaaatctt gctctctcag
     3061 actacgacct gcaataattt cattcttaac agcgtccatg taagttctgt ttccacctgt
     3121 caaattagca ttctcaacct ttttatcttg ataggtcaag atggcattcg ttgaattggt
     3181 tacatagtaa ctatccactc ccttcagttt agctgcctct tggacccagg attcttgcgg
     3241 ttttggcggt tcaacaggaa cttcctcttc ctttccagaa accgtaaaag ctgattgttt
     3301 ctgagtaaaa gacccgtctt tacttttttt aggagagaaa aagacgctaa tatttttctg
     3361 agatttagtc atatctttat tgacttgacg agatagggaa tcacccaaag ccataatcac
     3421 aacaactgat gaaacaccga taataatccc aatcatagta agcaaagaac gcatcttgtg
     3481 agccatgata gatgaaaagg caaatttcag attctgcatc ttagttttcc tcctttccta
     3541 actgagcact gtcagacgaa atgaccccat cccgaatgac aatctgacgt ttggcatagg
     3601 cagcaatctc aggctcatgc gttaccatga taatggtttt tccttcttta ttcaaatcaa
     3661 ccaataattg cataatttgg ttacctgttt tggtatccaa ggctcctgtc ggttcatccg
     3721 ctaggataat agaaggattg tttaccaagg cacgcgcaat ggctacacgt tgcttttgac
     3781 caccagataa ttctgaaggt aaatggtgac tacgttctgt caattcaacc ttgtctaaat
     3841 attcctcagc caacttgcga cgttttgaag acgaaactcc tgcgtaaatc aagggcaatt
     3901 ctacattttg cagagcattg agcttcgata gaagaaagaa ctgctgaaag acaaaaccga
     3961 tttgttggtt acggacctta gctagttgtt tttcaccaag cccagccact tcttgacctt
     4021 caagataata ttctccactg gttggtgtat ccaacatgcc aatcgtattc atcagagtgg
     4081 acttaccaga cccagatggt cccatgatgg ctacaaattc accctcattc acttctagat
     4141 tgatattttt gagaacctgc agttcttggt caccattacg gtaacttctg aagatatttt
     4201 ttagactaat tagttgcttc atcagccttc acctcttttc cttcttccaa ggaagatgtt
     4261 ggattactga tgaccttagc accgttcgtt aaaccagaag tgatttcttg attttctgcg
     4321 tcagcatttc ccaatgaaac ctcaactttt ttagcctttt gttgttcatc cacaatccag
     4381 acataatttt tactatcatc cattactaga ctgctaacag gaacaagaat agccttagtt
     4441 ttgcttttaa cctcaatgtt gacagaaaaa ccttgtttca aatcaccaac ctcgcctgtc
     4501 acatcaatag tataagggta tttagaacct gtattattcc cggctgctgg actagctgct
     4561 tcaccattgt ttttaggata gtcagaaata tagcttaatt tcccagtcca ttttttatca
     4621 ggatacactt tagaagtaaa gcttacttct tgacctacag aaaggttggc tagattgtac
     4681 tcagacaatt ctcccttgac ttgtaaattt tcattgctga caatatgaac cataacttgg
     4741 ctcgcccctg ttggagattt agaaacattg ctattgactt cgactacagt tccctctagg
     4801 gtactgagaa cagttgttgc atccaattga ctttgagcct tgcttaattg cgccgcagca
     4861 tctgcacgcg catcacgggc atcacccaat tgagcgtcaa tagaagcaac agaatttcca
     4921 gccactggag ttgggctttg caccgttgca tcttctcctc ctactggcgc tggtaactgt
     4981 ggagccggag ctgaagcggc ttcatttcgt gcttgattga gttcattgat atgacgatct
     5041 gccttagcta ctgctcgact agctgaatca taggccgcct gcgcttctga actactgtac
     5101 ttgactaaag cctgcccttc gctgacctta tcgcccacag aaacaaggat ttcatctaaa
     5161 tcacccttac tagcatcaaa ataaacatat tgttcatttt ttgctgttac tgtccctgac
     5221 aataaaacag aggatgccac gcttccttcc ttggcaacaa caagatgagt aggctcatct
     5281 tttagagcag tctgagaagg ttgtctaaag agtaaaatcc ccccggcacc caatacaact
     5341 acactcgcag caccgattgc tgcatacagt tgccactttt tagctttacc attctttttc
     5401 ttcataatga aactcctttt cttgtttaca atactttgct attataccaa atttccctcc
     5461 agcaaacaat gcagttcaga tggaaataat ggcagttcag gattaaacaa tcgttcggaa
     5521 ttttgctttt ctattgtact agatatataa tacactatct tgacttattt ggcaagcttt
     5581 tttgcaattt tttgtgcgta gcagattttt gcaatcaaat caaaaaaaga ataaaatata
     5641 actatcaaaa aagacgctct actatttaaa agattacaaa ggagttttca atgaaagaat
     5701 atgatatcat tgctatcggt ggaggtagcg gaggaatcgc taccatgaac cgtgctggtg
     5761 aacatggagc caaagcagcc gttattgagg aaaagaaatt aggtggaacc tgtgtcaacg
     5821 tcggttgtgt tcctaaaaaa atcatgtggt acggggcgca aatcgctgag actttccatc
     5881 aatttggaga agactacggc tttaagacta ctgatcttaa ctttgacttt gcaaccctac
     5941 gtcgcaatcg tgaagcctac attgatcgcg ctcgttcttc ttatgatggt agttttaaac
     6001 gcaacggtgt agacttgatt gaaggtcatg ctgaatttgt agattctcat actgtaagcg
     6061 taaatggtga actgattcgt gctaaacata tcgtgattgc tacaggtgcc catccaagta
     6121 ttcctaatat tcctggtgct gagctaggtg gctcttctga tgatgtattt gcctgggaag
     6181 aacttccaga gtcagttgcc attctaggcg ctggttatat cgccgttgaa ttagctggcg
     6241 tactccacac ttttggtgtc aagacagatc tctttgttcg ccgcgatcgt cctttacgtg
     6301 gttttgattc ctacatcgtt gaaggtttgg tcaaggaaat ggaaagaata aacttgccac
     6361 ttcatactca caaagtccct gccaagttag aaaaaactgc taaaggcatt accattcatt
     6421 tcgaggatgg taccagtcac acagctagcc aagttatctg ggctacaggt cgccgtccaa
     6481 acgttaagag cttgcaactt gaaaaagctg gagtgactct gaatgaacgt ggctttatcc
     6541 aagtagatga ataccaaaat actgttgttg agggaatcta tgctctaggt gatgtaacag
     6601 gtgaaaaaga actgactcca gttgcaatca aggctgggcg taccctatct gaacgtctct
     6661 ttaacggaaa aactactgta aaaatggatt actcaactat tccaactgtt gtcttttcac
     6721 accctgctat cggaactgtt ggtttgacag aagagcaagc tattaaagaa tacggtcaag
     6781 accaaatcaa ggtttataaa tcaagctttg catctatgta ctctgcttgc actcgcaacc
     6841 gtcaagaatc ccgtttcaaa ctcataacag ctggttcaga agaaaaagtt gtcggacttc
     6901 atggaattgg ctacggcgtt gatgaaatga ttcagggatt tgccgttgct atcaaaatgg
     6961 gagcaaccaa ggctgacttt gatgcaactg tggcaattca cccaactgca tctgaagaat
     7021 ttgtaaccat gcgttaatcg aaacaaaaga agctgatata aatatgtctg cttctttttt
     7081 aatgattttc gaatcaacaa aaaaattatc caacttgact agtcacgaaa atcggctgtt
     7141 acagtttttg ttaccttgtt tttaaaaaat ggttgacatc gactcctata tgagtataat
     7201 agttactata cattagaaaa gaggttaact attttgaaaa aagctcacgt ttatgctatc
     7261 cctgctattg gggctgctct cattgctgtt ttggcacaaa tcagtcttcc aattggacct
     7321 gttcccttca ctctgcaaaa ctttgcaatc ggcttgattg ctactgtctt tagaccgaga
     7381 gaggctgtac tttctgctgg actctatctt cttctaggtg ctatcggtct tcctgtcttt
     7441 gcaggaggtg gagctggttt tcaggcttta gttggcccta ctgcaggcta tctttggttt
     7501 tatctcgttt actctggact tacttcctct ctaaccaaca gcaagagtgg tgttgttaag
     7561 atttttcttg caaacctctt gggtgatgcc cttgtctttg tcggcgggat tctcagcttg
     7621 catttcctag ctggaatggc atttgaaaaa gctcttgttg tgggggttct tccctttatc
     7681 attccagacc ttggcaaact tctggctatt agttttatta gccgtcccct acttcaacgc
     7741 cttaaaaatc aggcttactt tactaactaa aaaaggatat cgagttatca tgactcaata
     7801 tccttttctt ttattttgaa aacttatact caatgaaaat caaagagcaa actaggaagc
     7861 tagccgcagg ctgctcaaaa cactgttttg aggttgtgga tgaaactgac gaagtcagta
     7921 accatacata cggcaaggca aagctgatgc ggtttgaaga gattttcgaa gagtattagt
     7981 tgcctttaaa ggcatccacc atcgtttgaa attcttcatt tgagagagta atccctttgc
     8041 ccattttagt atggtctgga ctccaagcac gaatatcaaa ctttgcaggg gcaccattaa
     8101 agctcacacg gttaatttcc ttggtccaac ctttttcgtt ttcagaaaga gtcaacaagt
     8161 gctcttcgat ttcaaatgta aattctgcca ttttcttctc cttttttagt ttcattagtt
     8221 tattcgtaaa atcttgtaga ttttaggaaa attttatata atattgatat aaaagaaggg
     8281 aggccaatat gagacataaa ttccagcaag ttctaaataa aatacatgat tttttaaatg
     8341 gatatgacca acctgaccag actgaaacca actcccttac agccactatt gaagaggcta
     8401 tccagaaaca aaccgctgtt caccttatct tatctgagac aagctttaca ggtgacatca
     8461 tcaaatatga tcagcaaggc cagcaaatta tcgtgaaaaa tttttccaaa aatgtgagcc
     8521 ggattatccg tataagcgat attcaacgcc tgcgatttgt cccctcaact gtccaaacag
     8581 cccaaaaaaa tagatttaag aaagagtgag atgtagttgc ttcatcccac tctttttctt
     8641 agcgaatttg ttcaaaatgt aaatgaactg cgatatgatc tccataacca cttctttcca
     8701 agtcacgttg taaacgatag gaaatatagt gttctgcaat ggtaatgtaa cctgcgccca
     8761 ataaacgatg ttcaaccata gattgaatca tactgatagt cgcacattcc accttggctt
     8821 cttgtaaatc caaaactacc ttcttagtga cttgagcaag attttgacgc aaatcatctg
     8881 tcaaaacata aacagtttgg gctgccttca agatggcttg gtaaatctta tctggattaa
     8941 attcagcaat ttcgccatta cgtttgatta cttgcatagg tttctccttt attctttgtt
     9001 ttctttgatt tctgccagca ttttttcttc ttctactgtc agttgataat gttcaagtaa
     9061 atctggtctg cgctcgtagg ttttctttaa actctcgtac aatcgccact gacgaatctt
     9121 ttcatggtgg ccactcatca atacatctgg cacgaccatg cctcgataat catagggacg
     9181 tgtgtactga ggatattcta aaagacccga agaaaaacta tcatcttggt ggctagactc
     9241 cttgccaatc acttctggaa tcaggcgaac tgtagcatca atcatggtca tagctgccaa
     9301 ttctccacca gtgaggacat agtcgcctag ggaaatctca tctgttacca aggtcttaat
     9361 gcgctcatca taaccctcat agtgcccaca gataaagatt agctcttcct cttgagccaa
     9421 atcttcagca taagcctgat caaactgctt tccagcagga tcgaggagaa taacgcgcgg
     9481 atttttcttt tcaatagcat caaaggaatc gaaaataggt tgtgctctga gcaacatacc
     9541 ctgaccgcct ccgtagggct catcatctac atgacgggcc ttttcagcat tttctcgaaa
     9601 attatgatac tggatatcca agagcccttt ttctcgagcc tttccaacga ttgagtgctc
     9661 cagtggagaa aacatctctg gaaagagggt taaaatatca atcttcatcg tctaaccctt
     9721 ctaagatttc cacatcgacc cgtttatttg gaatatcaac attgagaacc actggtggga
     9781 tataaggtaa aagcaaatca cgtttgcctt ttcgtttgac cacccagaca tcattagcac
     9841 ctggttgcag gatttccttg atggttccaa ccaagctatc accctcatag acttccaaac
     9901 cgataatctc gtgatagtaa aattcaccat cgtctaggtc attcaaatct tcctcagcga
     9961 ccttgagact atatcccttg tacttttcga tagtattgat atggtacata tctttgaatt
    10021 taataatgtc aaagttcttc tgtttacggt ggctagcgat ggtcactgtt tggacaaact
    10081 gatctttttc atcaaacaaa gccagctcag ctcctttttt aaaccgttct tctgcaaaat
    10141 ccgtcacaga caagactcgc atctcaccct gtaatccctg cgtattaacg attttcccaa
    10201 cattaaagta gttcatcttg tctcctgtaa tctccttttt tccatcttat tctgacaatt
    10261 ctcaaataat agccgcaatt ttttccgatt ctgaccattg taaataatgg tgattccctc
    10321 ctaaaatgag tttagtattg gaagtccaat attctgattc tctgtactct ttttctctat
    10381 aaggctgaca aaaaacaaat acaggaatat gagcttctat agatacatcc tcaaaatctt
    10441 cctcagtaat ctctccagat atctgaaatt ctggatcttg attttccaac tctaagcctt
    10501 tttcttgcat taattcccag atttttttat tcgtttcagg actaaatgtt gcttgagtta
    10561 agttcttaaa ataaagttca ggaccacact cgtcaatcag cctcatctgc tcttccattt
    10621 ctggataagg attttctgaa aaatcagcaa acatgacttt tttagttgtc ggttcaattg
    10681 ctactaaagt ctgacgctta attggtttct cgagtaattt gcaagctaaa attccactcc
    10741 aactatgtgc acaaagtata tattcagaaa ttcctaattc ttcaagtact tcataaaccg
    10801 catctgcaag attatctaga ttttttccag cttggtcatg aatcggactc ctacctgtgt
    10861 tcggaaaatc aattgtcaaa taaccaattg taggaggagg tttttcaagt ataagtgaaa
    10921 aattttcata acttggtagc aaacctgctc cgtttagaca aactagcact ttcttttgct
    10981 tttgataagt aacagagagg ctaccaattt ctgtagatac ttcaaacctc ttcataaaga
    11041 aatccactca ttctatataa tgaattatta aaaatcctta tcctttattt tatcacgttc
    11101 caaggatttt ctcaagttgg aggaaaggga caacatctct actttccctt caagaatcct
    11161 tccaaattat gtttatgttg gtaattaacg gctgcggttt tgtctttctc aaagacagtc
    11221 ttggtaaggt caatatgatt aatagctacg attgcgacgg tgtagtaaat gatatcagcc
    11281 agttctctgg caagttcctc gttcgaatcc tatcccttct tttcgaccag agcgcctatt
    11341 caaaacctcg gctacttctc cgacttcctc cactaacttc ataaagagac cttcatcagt
    11401 ccgagactgc tgttaatgtt cgagtaagta gtcttggaat tgcctaaacg ttcaatcttt
    11461 tatagtatat tgaaactaga atagtacacc tttacttcta aaacattgtt agaaatcgat
    11521 ttgactgtcc tgatcgattt gtcctgttat tatttctttt tactatatct tctattccac
    11581 acaaaaaagc gagacatccg tcccgccctt cttatttttc gtcaataacg attcttactt
    11641 ttttgtattc agttgggaca gagtagacaa tcgttcttat cgcagaaata gtgcgaccct
    11701 tacgaccgat tacacgaccc acatcgcttt gatcaagatt caaatgatat tccaaaaatt
    11761 ctggtgtatc ctcaatcttg atagttaagg catctggttg tgaaattaag ggtttcacaa
    11821 tcgcaataat gagattttca atcgtatcca tctgtcaacc tactttaaac ttattttgag
    11881 aatttagaat cgtggaattt tttcaatacg ccttcttttg aaaggatgtt acgtactgtg
    11941 tctgaaggtt gagctccatt agccaaccat gcaagaacgc ggtcttcttt caaagttact
    12001 tggttttcag caacaagtgg gttgtaagtt ccaactgttt cgatgaaacg tccgtcacgt
    12061 ggtgaacgtg aatctgctac gttgatacgg tagaaaggtt ttttcttaga acccatacga
    12121 gtcaaacgga ttttaactgc catttttaaa gtctcatttc tttaattttt tatttcggtg
    12181 aaatagctga gctatttagc acatgttcta ttatagcaga tttctggcag gtgtcaagaa
    12241 aaaaacttga cagactataa atttcttaaa gcatttagaa atttgttaga ataggaaata
    12301 aatgtttgaa agatgctatc cgtgaatact attttagaaa aattttataa agaacaccaa
    12361 gtcaaaccct tcatatcgcc tgaacgagat ttggatactt ggcttctaag tcccaaaccc
    12421 gttcccaagc gaaatatgga cttattagca gatgattcac tagcaggaga tatcatttta
    12481 ctatggagaa tccagtttgg tacttttacc actgaaacat gattttaaaa actcccattc
    12541 gaatatgatt caaaattcgc ttagaatcaa tgttttccca ctttttcaaa aaataaattt
    12601 tcatctaatt taaataactt tcaattaagt gtgaattttg cttaaaatca taaaaaaaca
    12661 ccccatggtg tgaaccatga agtgttgtaa atgctgtatt gtagctagtt cttaacgttt
    12721 agagaactgg ctagctttac gagctttctt aagatctggt tccctaaata ctttgagtac
    12781 acttatggca ttgatgcccc taaacatcta aaaactctgg tagaaaaaga gtatgctctt
    12841 gtcgaaactt cttttgactc acttgaccat ctaaatacta ccatgaaaaa gaatatcctg
    12901 aagaagaagg gagttactgg actttctaaa atgaaatctt gcgacctgga tcaagctctt
    12961 catgagcatt tttcagaaga agaattagct ggtcactttc atgtccttct atggactttt
    13021 ttacaatggc attgctatca cacccaatac ctatctaagc gcctggttcg taaactttat
    13081 tgcagctctt cctctaaatt tcctaattgt tgaaccaatt gcccgtttta tactaagttc
    13141 ttttcagaaa ccatttactg gggaagaagt tgaagaagtt gaagattttc aagatgatga
    13201 tgaaatccca actattatct aagccagttc tgtaaactac taatatttga aatccacttc
    13261 cttttagggt acaatggtat aaatgaattt ttgagaggaa cagaatgaaa aaactagcaa
    13321 cccttctttt actgtctact gtagccctag ctgggtgtag cagcgtccaa cgcagtctgc
    13381 gtggtgatga ttatgttgat tccagtcttg ctgctgaaga aagttccaaa gtagctgccc
    13441 aatctgccaa ggagttaaac gatgctttaa caaacgaaaa cgccaatttc ccacaactat
    13501 ctaaggaagt tgctgaagat gaagccgaag tgattctcca cacaagccaa ggtgatattc
    13561 gcattaaact cttccctaaa ctcgctcctc tagcggttga aaatttcctc actcacgcca
    13621 aagaaggcta ctataacggt attaccttcc accgtgtcat cgatggcttt atggtccaaa
    13681 ctggagatcc aaaaggggac ggtacaggtg gtcagtccat ctggcatgac aaggataaga
    13741 ctaaagacaa aggaactggt ttcaagaacg agattactcc ttatttgtat aacatccgtg
    13801 gtgctcttgc tatggctaat actggtcaac caaacaccaa tggcagccag ttcttcatca
    13861 accaaaactc tacagatacc tcttctaaac tccctacaag caagtatcca cagaaaatta
    13921 tcgaagccta caaagaaggt ggaaacccta gtctagatgg caaacaccca gtctttggtc
    13981 aagtgattga cggtatggat gttgtggata agattgctaa agccgaaaaa gatgaaaaag
    14041 acaagccaac tactgctatc acagtcgaca gcatcgaagt ggtgaaagac tacgatttta
    14101 aatcttaaaa accaaaaaaa tacagtatcc acattcggta ctgtatttct tttactctca
    14161 ttcttaagtt aaattattaa aatcccatat ttggtctatc cagccttcat aaaagtctgg
    14221 ctcgtggcag accataagga tagatcccct atattctttg agagcgcatt tgagctcatc
    14281 ctttgcatcc acatccaaat ggttggtcgg ctcgtccagc actaaaacgt tgttttcacg
    14341 attcatcaag agacagaaac gaaccttggc ttgctctccc cctgataata cttgaatctg
    14401 gctttcaata tgtttggttg tcaaaccaca acgggcaagg gctgcacgga cttctgcttg
    14461 attaagggca ggaaaggcat tccagacagc ttcaagagga gtttggcgat taccaccttc
    14521 tacttcctgt tcaaaataac caagttctaa ataatctcca cgctccactt ccccagcgat
    14581 tggcgagata atgcccaaga gactcttcaa gagagttgtt tttccaatac cattagcacc
    14641 aataatcgca accttttgat tgcgttcgaa ggtaagattt aaaggcttag taagaggacg
    14701 gtcgtaacca atttgcaagt tcttggcttg gaagataaag cgccctggtg tacgagctgg
    14761 tttgaaatca aaggatggtt ttggtttctc actttggagt tcgataatat ccatcttatc
    14821 caatttcttt tgacgagaca tagccatatt acgagttgca acacgggctt tattacgagc
    14881 cacaaagtcc ttgaggtctg caatctcttt ctgatggcgt tcgtaggctg cctctagctg
    14941 agatttcttc atagcataaa cttcttggaa ctggtagtag tcaccagagt aacgcgtcag
    15001 ctgttgattt tccacatgat agacaatatt gataacgtca ttgaggaatg gaatatcgtg
    15061 cgaaatgaga acaaaggcat tctcatagtt ttggagatag cgcttgagcc aatcaatatg
    15121 ctcagcatcc aagtagttgg tcggctcgtc caacagcaaa atatcaggct tttcaaggag
    15181 aagttttgcc aaaagcacct tggttctttg cccacctgac aaagaagtta catccgtatc
    15241 catgccaaag tccataacac caagagcacg cgctacttcg tcaatcttag catccaaggt
    15301 atagaaatca cgactctcca gacggtcttg aagttctcct acttcttcca tgagagcatc
    15361 aacatccgcg ccgtcttcag ccattttcat atagaggtca ttgatacgag cttcagcttt
    15421 gaaaagctca tcaaaagccg tacggagaac atcacgcacc gactgtcttt cagcaaggac
    15481 agagtgctga tccaagtaac cagccgtcac atatttggac cactcaacct ttccttcatc
    15541 tggcagcatt ttaccagtca cgatactcat aaaggttgat tttccttcac cattggcacc
    15601 gaccaggccg atatgttctc ccttgaggag acggaaggac acatcttcaa aaattgcacg
    15661 gtcaccaaaa ccgtgactca gatttttaac ttctaaaata ctcattttaa ttccttatct
    15721 tgtttttatg taatcgttta taaaggagcc aagccagata gccacccaaa gtgttggtcc
    15781 acaaatcatc aatctcaaag acacgattga aatcaaagaa aaagtccaag attaattgcg
    15841 tacactcgat tccaagactc acaagaaaac taaaaagaag gacctttttt gttttccgca
    15901 aatttggaaa tagataaagg agttggaaaa tcagaggaaa aaacaagaag acattgagga
    15961 tattttgtaa aaaaatccaa cataattgtc caatgtcact cacttcgccc agtttccaga
    16021 gagaattgaa aggagtcaaa agaaaaacca ggcgtccaag atgctgaata tctggagttc
    16081 ccactcccac ggtagattgt tcttgaggag taaagcaaaa acagacaatg caaatgctat
    16141 agaaaatgac tccccagacc aaaatatgat tataagtctt cttcatcatt aaggatttac
    16201 cgctgcgact gccttctggc ggtcacgttt cattgtgtta gagcgcaatt gtccacaagc
    16261 tgcgtcaata tctgtaccat gctcttgacg aaccacacag ttgacccctt ttttcttaag
    16321 cgtatcatag aaagccaaca cgcgctcttt gggactacgg ctatattggt catgctcact
    16381 aactgggtta taaggaatca agtttacata agacaatttc ttgatgttct tgagcaattc
    16441 agccaattcc aaggcttgtt ctacaccgtc gttgacttca ttaagcatga tatattcaaa
    16501 ggttacacga cggtttgttg tctcaatgta gtattcaata gcagcaaaga gtttttcaat
    16561 cggaaaggca cggttaattt tcatgatact tgaacgaagt tcattgttgg gtgcgtgaag
    16621 agacacggca agattgacct gaaccccttc atcagcaaag tcacgaattt tatgagccaa
    16681 acctgaggtt gaaaccatga tgtgacgagc accgatagcc attcctttat catcattgat
    16741 agtacgaaag aaattcaaaa cattgttgta attatcaaag ggctcaccaa ttcccatgac
    16801 aacgatatgg ctgacgcgtt catcctgacc acgctcatca aagtatttct gaaccagcat
    16861 gatttgcgct acgatttcac cgttattgag gtcacgctgc ttcttaatca aaccagaggc
    16921 acagaaggta caaccgatat tacagccgac ctgagtggtc acacagacag ataaaccata
    16981 gtgttgacgc atgagtacag tctcaattaa cataccgtcg ggcaattcaa agagatattt
    17041 gactgtacca tcagcagact cttgcacaat acgttgtttc aagggattga ccacaaactg
    17101 gtcattgagc ttagcaatca aatccttgga aaggttggtc atttcttcaa atgactgcac
    17161 acgtttacgg tagagccatt cccagatttg atctgtacgg aatttctttt ctccctgctc
    17221 caatacccat tcctgcatgg tttgatgtgc caaactatga attgagggtt tcatttcttc
    17281 tccttattct ctactcactt ctgacgaatg acaaaatgac gttgtccctt gtcctctttc
    17341 tgagaatgct ggtctttctg acgacgtcta tttttcttat ctgcattcga ctttcgttta
    17401 gtttgagtcg gtttctttcc ttttctagaa ggtgtttctt cttccgtctt acgcattttc
    17461 ttgtcaaatg atgctcgctt aggggcttca ttttctaaga caaaataggc acaaccataa
    17521 ctacaatact ctaaaaggta gtcttgtaaa cgactgattt tttcaagttt ttcttctgtt
    17581 cggtcatcct tgtaaaaacc tcgtaggcga agctgttcgt tgctccagtc ccccacgata
    17641 taatcaaact tggttaagac ttctgaaaaa cgctgattaa aagtcgtcac atcaaaggca
    17701 tccttgatat tttcaaccaa ggaaaaagct atcccttccg tttcgacctt gtccccgtgt
    17761 aaatggaact ccggaccagg aaacttgtta tagttgtata attcaggtgc aatttctttt
    17821 cgcatagata tcctttttcc acgattactt aatactttat tctaccataa tttctagcag
    17881 ttagcacgtt tctcataaaa atgaaaaaag tctgacgatt ttatcagacc agaatcttat
    17941 aacctaaaaa gagaagaaca attcttccct ccaactatca ttatttagca gctgcgtaca
    18001 attcatctac tttattccag ttgattactg aaaagaaagc tttgatgtag tcaggacgca
    18061 cgttgcggta tttcacgtag taagcatgtt cccaaacgtc caagcccaag attggttttt
    18121 taccttctga gattggtgtg tcttggtttg ctgttgaagt cacttcaagt ttcccttctt
    18181 tgttgacaac caaccatgcc caacctgaac caaaacgagt tgttgctgct gcagtgaagg
    18241 ctgcttggaa ttcttcaaat gaaccaaatg ttgcatcgat tgctgctgcc agttctgctg
    18301 aaggagctgt tttctcggga gtcatcaatt cccagaaaag agcgtggttc aagtgtccgc
    18361 caccattgtt gataagtgct tgacggatat cagctgggat agattctaca tcagcaagca
    18421 aggcttcaag gtcttcaccg atttcagggt gtttttctaa agctgcattg gcattgttga
    18481 cataagtttg atggtgtttg tcatggtgca aatgcattgt ttccgcatcg atgtatggtt
    18541 ccaaagcgtc gtatgcatat ggaagttctg gtaagataat agccatctgt aatacctctt
    18601 tttctttcta tatgaaaatg ataacgcaaa cattcacttt tttcaagttt tttgcttata
    18661 gataaggaaa tcactgacat actttctaat aaaataagca aatcagcaag aaacccacga
    18721 caagataatc ctgacgcggg ttgtagtttc aacaaatgtc aattgacctg actagcaatc
    18781 tgtaagagtg ccttttcaaa aaggaaacct ttttcataaa gacctgtctt aatctgatag
    18841 tctgtctcaa tcaaatagga aatagcttgc ttcagaaagc tcaaagaaag tcctctcgaa
    18901 tctcttaatg caaacttgat ttgataagga tttgggttac gtcccagata actacctaaa
    18961 ctacttgcaa tctgcgattc tgtttggcca gactccgcca aaatcttcac ctgagtaaaa
    19021 gtccgaaatt gtcccagcat gactgcaatc agtttgattt catcttcccc ttgcaaggtc
    19081 aagtctctca ccaaatcgcg cgcctgatcc atctttttag tcagaataaa ctgagttaaa
    19141 tcaaaaatat tgtcctgcaa ggtcttggga attgcgttaa caatatcctc ttcctcgata
    19201 acagaatccg ccttatagga ctgtaaaaag agaagatttt tctggatttc gctaaattga
    19261 aaccccgact tgatgaggag attttcaaaa gaatgattgg taaactgcag accttgtttc
    19321 tgactccact tttggaagta ctggcgcaat tcttgttctt ttacttctac tgcatcgaag
    19381 gccttggcat cacgcttaag taatttgact aaccgtcttt tgctatccag ctttccttct
    19441 gcaaagatta tcaacttggt tgttggagaa ggattgtcaa ggtattcctc aaatgactta
    19501 agctcatcat ctgtcaaaaa gcgtttctta gcagtcgtga tatccataaa ataatctaat
    19561 atcacgattt tctcatccgc aaagaaagga aggctgacca actccagttc cacatccttg
    19621 taaactactt ctttcatatc aaagtaggca aagttgaggt cagcagaatc atacccaatc
    19681 tgtttcaaca cttgactctt catcacttca aactgaccct gatctgtccc tgtaaatagg
    19741 ctcaggctcg gtaaatttga taaagtcaac ttctgacttt cttcaatggc tagcatcgtc
    19801 tctcctttct tcagattttt cgatttaatt tagtcaatat agcgcaattt cccacggaaa
    19861 tcttctaagc tctcgtagcc tttttccacc atgattgctt tcagttcatt ggtaatgcgg
    19921 tcaaaagcac tgacgccttc tttgtgaagg gtcgttccca cctgcaccat acttgctcca
    19981 cagaggatgt gttcaaaggc atctcgacca gtcagaacgc cacctgttcc gataatttgg
    20041 atttgaggat ttaaacgttg ataaaaggcg tgaacattgg ctagagcagt cggtttgatg
    20101 tattctccac caattccacc aaaaccattc ttaggccgaa taacgacaga ttcgtcttct
    20161 atatagaggc cgtttccgat agagttaacg cagttgacaa acttgagcgg atatttgttg
    20221 aaaatagctg ccgcttgatc aaagtgaaca atatcaaaat aaggtggcaa tttaattcca
    20281 agaggtttgg tgaagtaagc aaacacttct gccaaaatcc ggtctgttgt ctcaaaatca
    20341 taggcaatct gaggtttacc tggaacattt ggacaggaaa gatttagctc agtcagacca
    20401 cgaaaatcac tctcttggac ttttttcaaa atagtatggg tttcctctgg agacatgccg
    20461 accagagata agaagaaagt tcggttcgac tctttttcct gcaaatctaa aagataatcc
    20521 aaataatagt ctaagccatt atttggcaag cccatagagt tgatggaacc aagtggaaca
    20581 tcttggtagc gtggctcagg attcccctga cggaagtcca aggtcgctgt cttagtaaca
    20641 aaggttcctg ccgctgagtt tttgacctct tctaactcct ctatcgtcat acaagccaca
    20701 cctgctgcat tcatcaagca attgtcaaac tcaaaaccag caatttgtgt tttcgttgat
    20761 accatgattc taatcctcca gatttctttt attgctaata ttataccata attttaattc
    20821 taggtttact a
//
LOCUS       DAVDZK010000039        20692 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVDZK010000039 DAVDZK010000000
VERSION     DAVDZK010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.040"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(510..2237)
                     /gene="ezrA"
                     /locus_tag="VUX16_001719"
     CDS             complement(510..2237)
                     /gene="ezrA"
                     /locus_tag="VUX16_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET8124636.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVEEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2319..4265)
                     /gene="gyrB"
                     /locus_tag="VUX16_001720"
     CDS             complement(2319..4265)
                     /gene="gyrB"
                     /locus_tag="VUX16_001720"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET8124637.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKREG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSESRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4280..4843)
                     /locus_tag="VUX16_001721"
     CDS             complement(4280..4843)
                     /locus_tag="VUX16_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET8124638.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDISNKGGHHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4928..5482)
                     /locus_tag="VUX16_001722"
     CDS             complement(4928..5482)
                     /locus_tag="VUX16_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET8124639.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLSAICAA
                     PIALNQAEILKNKRYTCYDGVQEQIFDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5493..6716)
                     /locus_tag="VUX16_001723"
     CDS             complement(5493..6716)
                     /locus_tag="VUX16_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET8124640.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6753..9203)
                     /locus_tag="VUX16_001724"
     CDS             complement(6753..9203)
                     /locus_tag="VUX16_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET8124641.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDYYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEEIYRNQSILTSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPHNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9403..10332)
                     /locus_tag="VUX16_001725"
     CDS             complement(9403..10332)
                     /locus_tag="VUX16_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET8124642.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10472..10759
                     /locus_tag="VUX16_001726"
     CDS             10472..10759
                     /locus_tag="VUX16_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET8124643.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10793..12127)
                     /gene="ciaH"
                     /locus_tag="VUX16_001727"
     CDS             complement(10793..12127)
                     /gene="ciaH"
                     /locus_tag="VUX16_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET8124644.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12117..12791)
                     /gene="ciaR"
                     /locus_tag="VUX16_001728"
     CDS             complement(12117..12791)
                     /gene="ciaR"
                     /locus_tag="VUX16_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET8124645.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12900..15446)
                     /locus_tag="VUX16_001729"
     CDS             complement(12900..15446)
                     /locus_tag="VUX16_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET8124646.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEITARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15569..16009)
                     /locus_tag="VUX16_001730"
     CDS             complement(15569..16009)
                     /locus_tag="VUX16_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET8124647.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVKPFNRVSADHAYKEGE
                     GNKTLVYWRQVHEDFFRDCLGEAGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15984..16853)
                     /locus_tag="VUX16_001731"
     CDS             complement(15984..16853)
                     /locus_tag="VUX16_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET8124648.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTKVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16831..17331)
                     /locus_tag="VUX16_001732"
     CDS             complement(16831..17331)
                     /locus_tag="VUX16_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET8124649.1"
                     /translation="MEIKKHFGVYAVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETRFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17342..18040)
                     /locus_tag="VUX16_001733"
     CDS             complement(17342..18040)
                     /locus_tag="VUX16_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET8124650.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18033..18299)
                     /locus_tag="VUX16_001734"
     CDS             complement(18033..18299)
                     /locus_tag="VUX16_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET8124651.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDAI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(18367..19293)
                     /locus_tag="VUX16_001735"
     CDS             complement(18367..19293)
                     /locus_tag="VUX16_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET8124652.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19368..20183)
                     /locus_tag="VUX16_001736"
     CDS             complement(19368..20183)
                     /locus_tag="VUX16_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124653.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWENFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILILAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRWCLVQDSPKMKIGTYI
                     VVGILVLLVVMGYVGIGSFVQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20187..20507)
                     /locus_tag="VUX16_001737"
     CDS             complement(20187..20507)
                     /locus_tag="VUX16_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET8124654.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6235 a         4535 c         3671 g         6251 t
ORIGIN      
        1 atgtcttcca aacgaggaaa ctctcgtaaa caaagaggtt ttagaggcct atttaccgtg
       61 gactaaagtt gtacaagaaa agtgcaaata agaaatctcc agattaggaa ctatccgtga
      121 gttctctaat ctgaagattt ttcaatagac ttcgttattg gacggttacc aagttactca
      181 aagtacagat ttgaagctgc agataagact gacgaaatca ctttaatact aaatgaaaat
      241 caaaaagcaa actaagaagc tagcctcagg ctgctcaaag tacagctttg aggttgcaga
      301 taaaactgac gaagtcagta acatacgcac ggtaaggcga cgctgacgtg atttgaagag
      361 attttcgaag agtataaaac actgttttga ggtggtggat aaatcggctg ggcaaaaact
      421 caatctcagg agaaaatgaa gtaaatctcc ccacaactat agaaaaagat ttgattctgc
      481 tcctcacaca ataaaatctt tttcttttat taaaaacgaa tcgtttcacg tgttttctca
      541 tatgaggtaa caaagcgatt ggttacacca ggctcttcca cttccaatgc ttgagaaatc
      601 ttgtcaaatg aagcgtgata atcaaattct ttttcaaaaa tatctaaagc ttcgttaaat
      661 gcttcttgaa tgcgttcatc aaatgagcga tagcggttag aatattgcaa gagttgctct
      721 gtcaaagttg catattgtac aatattataa gtttccgttt ctaaagcttc catatcattc
      781 gttgcaattt caagaactcg ggtaacagat tcaatgttaa tcattttttg ttctaactca
      841 accattaaat cctcggtatt attgcttgcc gtaaagaata acttcaagaa agtttgtgga
      901 atacctggca gattgcgttt ttccatgtat cgcttgatag tatggagacg attgacataa
      961 acattggcct tttgacgtgc attaatatca tctttctcaa tttgtgtcag gcgctcacta
     1021 actgaaattt gctcatcttc aatatctttt agttgagttt gtaaatcctc aagattttct
     1081 tcaagaactg aataagcttg ggttggttct tcttgatttg aagttacctc aacaatggct
     1141 gcctcaaaac tctctaattc tgtctgaata cgacgaacat ggcttgcagc tgtctcagga
     1201 agtaaatagg tcttgttcaa acgtgcaata tcttctccca ataaagtatt attctctttc
     1261 atatgttgaa ggtaagttgg aagagttgca agtagatttt ccactacttt ctgagcagca
     1321 atttctcgag taaaaatatc atacaaggca ttgatttcct cttgtgcctg tccattctca
     1381 tattcggcat tatccaattc caactgacga atattctctt ggtttttctt gaatgcttca
     1441 taaagcaagt ggaaacgcgc ttcaatatcc gtttcaacaa aatgataatt agcatcaatt
     1501 agtttacgat aaccggcttc caaatcctgt aattgatctg gcaattctgt agaaagcgtc
     1561 gtaaccaagg ctggaacacg atccacaata tgacttaagg ccaaaatgtg attttctgta
     1621 ttatccaaaa tcactgcggc ttccacaggg tcacccgatg aattcaaggt tacaaattgt
     1681 gaaaattcag attggatatt ttctaattgt ttttcaattt catccaaggc ttgaccatac
     1741 tgttctgaat tttcagcaac tctatgctga agttcctcaa ataaatccaa agcatgaaga
     1801 acacgaccac tatttttaga ttcttgcttc tctaagtctg ccaaagcatt gcgaattgcc
     1861 gcaatatctt cttcaatcaa agtaatttga ctctcaattt ggtcaatttg atgactggcc
     1921 ttgagaaaac gaaatgaatg gttatagcct tctgcttcaa agagattatt ttcaatatcg
     1981 gcaaaagagt tgagagataa atcgacccat ttttgattcc attcacggaa agccacttga
     2041 ctttgtccaa tcaagtgcat attttttaca gcttctactt catcatttac tggaagattg
     2101 tatagttctt cttttctttc ttctagcgcc tctaatctcc cctcgtttcg cttacgtaga
     2161 aagattgcca ctacataagc cagaactaaa atgactgcaa ttgcaaccat taaataaatt
     2221 agttgtccat tagacatatc aaactccttt tttacttgaa acaatcgtaa cgattatatc
     2281 atatttttta gaccaaggga actacttctc cctatttttt agacatcaag tgtactatag
     2341 acagcatttt cttcgataaa ctcacgacga ggctctactc gatcccccat caacatatca
     2401 aagattttat ctgcttctgc agcatcatct acagaaactc tagccatcaa gcgatgttcg
     2461 ggatccatgg ttgtttccca cagctgatga tcgtccattt cacctagccc cttataacgc
     2521 tgaatagtcg gtttggtacg actttcacta taacgggcta aagcttcttg gagtttgatt
     2581 tcttgatctg cacccggctg gatatattct ttaatctcgc ttccaacctt gacaccatag
     2641 attggtggct gggcaatata aacataacca gcttctagga ttggtttcat ataacgataa
     2701 atcaaggtta aaagaagggt acgaatgtgg gctccatcga catcggcatc ggtcatcaaa
     2761 acgagttttt ggtaacgggc tttcgaaaca tcaaattctg cgccaaatcc tgttcccatg
     2821 gctgtgaaaa gactacgaat ttcttcgtta gctagaatct tatccatact tgctttttca
     2881 acgttcaaaa tcttaccgcg aattggaagg atagcctgaa actcacggtt acgaccagat
     2941 ttggctgatc caccagctga gtctccttcg acgatgaaga gttctgtttc agcagggtta
     3001 ttagaagaac agtctgctag tttccctgga aggttggaaa tttccaaacc agatttttta
     3061 cgtgtgactt cacgcgcacg cttggcagcc acacgagcct tggcagccaa aattcctttt
     3121 tctacgatac gtttggcaat ctgtggattt tccatgagga aatcggagaa ggcttcactg
     3181 aagaggcgat tggtaatctt gaccacttcg ctatttccca atttggtctt ggtttgtcct
     3241 tcaaactgtg gatttgggtg tttaactgag ataactgcag ttaagccttc gcgaacatct
     3301 tcccctgtta ggttgtcttc attgtctttc agtaacttat ttttacgagc ataatcgttg
     3361 ataacacgtg tcaaggctgt acggaaacct tgttcatgcg ttccaccttc atgtgtatga
     3421 atattattgg cgaaactcat gacattttca tggtaacccg ttgtgtactg catggctacc
     3481 tcaactgtga tatcatccat ctcaccgtct gtatagattg gtgtatcaaa gattacatcc
     3541 ttgttctcgt tgatatattc aacgtaactg gcaatcccac cttcataatg ataatgcttg
     3601 gtttgttcca aaccttcacg cttatctgta attgaaattt gaagaccgcg atttagaaag
     3661 gccaactctt gaatccgttt atttaattta tcaaaatcaa agattgttgt ttcagtgaag
     3721 atttttgggt ccggtgtgaa gtgaacagtt gttcctgttt tatccgtatc tccaactatt
     3781 tcaagatctg cgacaacatg accacgacgg tattcttggt aatgaatctt accatttttg
     3841 tgaacatgaa cgtctaattg agttgaaagg gcattaacaa ctgacgaccc caccccgtga
     3901 agaccacctg aaaccttgta tccaccaccg ccgaactttc ctccagcgtg aaggactgta
     3961 aagacggtct caacagcagg acggcctgtt ttttcctgaa tatcgactgg gataccacgc
     4021 ccatcatcca caacagtaat cgaatcatct ggctcaataa aaacttgaat atggctggca
     4081 aatcctgcca aggcctcgtc aattgagtta tcaacaattt cccagactag atggtgaaga
     4141 ccttcttttg aggttgatcc aatgtacatc cctggacgca tacgaacagc ctctaagccc
     4201 tctaaaactt gaatttgact ggcatcataa tcctgtgcct gcagattttt gatttcttct
     4261 gtcatcttat tcctttttct tatatgtcta atacttgtct taaattcacg atactggtaa
     4321 acaagtgggt atcaagtcct gcagcttgac ctgcttcgat atcaatcggc cgatcaccaa
     4381 tgacaagacc agagctaatc tgatactttt ctcttaaata aagcatggat tcgggattcg
     4441 gctttctctt aaagcctgag ctagaagtca ccacttctgt aaaataagct gctatagagg
     4501 ttttttctaa aatttccaaa acctgatcat ttcgatgaga gaccaaaaaa tgatggccac
     4561 ctttatttga aatgtcttcc aataggtcag aaactccttc aaataaaatc gggtgttcaa
     4621 gctctctggc ttcattttcc ttgtactttt ctaaaaaatt ctctaaattg ggagcgaatg
     4681 tctcaatcgc aaaaggagta gaaaccttta aagcttgata gacactgtca tggtcttgtg
     4741 tgataccata cagtgccaat gtttcaacaa atgcagctgt tgaagtttca taattatcca
     4801 gtaaagttcc acctaaatcc cagatgtaat cgtgatattt catacccttc attatagcat
     4861 ttttttatga aaaaagcgat gatttccctg agttttccac ataaaaaacg agagaataac
     4921 tcccgtttta ctgattttta ccaaagacat ctcgatagag cattcctgtt cgtaaactct
     4981 ctgcgtcccc tcctagttgc tccaccaact cgtaggcaaa ggcaagggct gttgaaggac
     5041 cccgactggt tgtcaactga ccatctacca ctactgtttc cttgacgtag tgaccatcaa
     5101 agatttgctc ttgaacgccg tcataacaag tgtatcgctt atttttcaat atctctgctt
     5161 gattgagggc aattggtgcc gcacaaatgg ctgatagttt cttcccttct tgctcgaagc
     5221 tttgcaattc ttgaatcaag gtctgattat cacgtaaatg tgcagaacca ggcatacctc
     5281 caggaagaac aatcatatca tagtctgata aatctccatc aaagacatga tctgctctta
     5341 cttggattgc atgcgaaccc gttacttgct cttcaaaacc aaccatatca catgtgatat
     5401 tggctcgacg caagacatct acaactgtca aggcttcaat ttcttcaaag ccctgagcta
     5461 acataacggc tacttttacc atgattttct ccttatttaa tttgttttaa tacaaccttt
     5521 ttccgtttga atgggacttt tccgctcttt tcttcagcta aattagtctg gtaactcatc
     5581 gataaaagca aaccaacacc aatcaaatta ctgataatag ctgatccccc ttgcgaaatg
     5641 aaaggcaagg gaatccccgt caaaggaagt agtccagtca cagcaccgat attctcaaag
     5701 atgtggaaga gcaacatcat aatcaaacct gtggaaatat aagtgtagaa ctggttattt
     5761 gatttaagag taatcttcaa catacggtaa atcaacatga gatagagggc aataaccagg
     5821 acagagccaa taaagccaaa atcttctgca ataaccgtaa aaatcatatc tgactctcga
     5881 actgggataa gcagattcga agcattaaat ccctgaccaa ataagccacc actcccaatg
     5941 gcaatctgcc cttgagcctg ctggtaagtc gttgtttggg caaactcaaa gggattgagc
     6001 caagccaaaa tccgattaat ttggtaggtc ggcattccaa tttggtgaag aaaagctcgt
     6061 ccgtccttgc taataaagat agctaagaaa ccagcaactc ctgttacagc agtcacaaat
     6121 actgggataa taattttcca agaaacccct gataataaaa cgattcctga gaaaatggct
     6181 acaaaaacca aagccgtccc caagtcactt tgaagtgcta aaagaactag gactggaatg
     6241 gtaaagagaa tcatccagaa aattaacaaa aagtccagcg gaaccgtgcg tctccattcc
     6301 ttatgtttct ttgtaaattg gacaatgaca cgagccaaca tgaggatata ggatatcttc
     6361 ataaattctg acggttgaaa tagggtaatt ccatttattg atacccagtt tttggcaccc
     6421 gttgatgcaa ctaagcttgg attataaaat acaatcggca agatcataag tcccaagcct
     6481 aaaatatata gaaagggggt caccttccaa agaaattctg tattaaagag catgaccaca
     6541 aaaccaatca caagccccaa ggcaatccag gcgacctgct gccctaaaat gggcagaata
     6601 ttattgggat aatcatgact aacggctata tagatagcca ccacaccgat gaccagtaga
     6661 aaaaatactg gcaagagcaa actataatcg actctagagt cgagagaacg tttcatatat
     6721 actaacctta tactttcata caatactatt tatcaaagtt cattaaaaaa tctatcaata
     6781 gcctcgtcaa cttcggatcg agagatggtt ttaacagtcg cttcttctgc tagagatgct
     6841 actatttgtt tgccatatcg ttttccgacg attctcctat ccaaaataag agttaaggaa
     6901 cgttggtatt cacgtctcat acttcttccc aaagcctgtt ttaaacgaat aatggccatt
     6961 ggcaattgat aatcataaaa ggcatttttc ccttcttgat tcagttcttg attaatcttt
     7021 ttcgtcaagg gttcttgagg attttggaaa ggaagcctcg gtacaacttg aatcacaaaa
     7081 ggatggcttg aaaaatcaac tccctcccag aaacttgctg caccaagcaa gatttgttgt
     7141 tcaccttttt caaagcgttt ctttagctga tgaacatccc catttttata ctgggccaag
     7201 tggctaactg taagtaaatc cgatactgct agaagcatgt ctttagcggt aaagagaacc
     7261 aaaatcggtt gctggaaagc ttgaatttcc actagtaaag cagctacctc tctggcatag
     7321 acttctaagg aggtttctgt taccagaggg aaatctttga ccatgaccac ttcttgttcc
     7381 tgttttcccc gagattcaat cttgacaaat ttggcttcag gatagcctaa aaggtctgcc
     7441 aaagaaaccc tctgactaat ctcaagagta gccgatactc ccaagacttg gcaactctca
     7501 ggaagtaaag aggacagaag agtacggcct gattttgtag aagaaatctg aattttcttt
     7561 tgactcgttt cagttacttc aagccagtaa tcaccttcag ctgtaaaata gcgaaccagc
     7621 tcatcaaagc cttctacttc taattctgaa aaatactgat ggagattgtc cagagaatct
     7681 aagatatttt tcctagattt accagactga aattgttcta tcaagtagag acactcaaag
     7741 cgaatacttt ctagtatccg ttgttgaacc ctgttttctt ctcctactaa agccttatca
     7801 attaaatcga taatagattg tatatcgtag gtctcttgaa gcagattttc tagagctaac
     7861 aaaatctttt ggacttcatc aataatcagt aaacggtcac tgacaaattc aggattatct
     7921 tcaagtctgg ttacgagata ggcatgatta gtcactaaaa gcttgcaagt ctctgccctt
     7981 tcttgactac gtttccaaaa atcttccgtc acaaataagc tctgggatga taaattccca
     8041 tcatgacgaa ggtctgctag aaaatgttgg taacggtaga gttgcccgat ttcatccaaa
     8101 tctcctgtct ctgtctcagt aagccagacc aagacttgca ttttaaagcg tctaaataag
     8161 cgattttcat cattttcctg caaggaatga taaaaggcat ccaacttcag ataattgtgt
     8221 ggtcccttta agctatgaat atctgtatgg aacacttcct tgagacgttt accttcttct
     8281 tccatgattt gattttgaag aatctttgtc ggaacactaa gaacaatttg tcgctctttg
     8341 gattgagata aagcgggtaa gagatagcca taggttttcc caatccctgt cggcgcttga
     8401 atcagagaga caggttcatc tttcaatagc aagccaacct ctttagcaaa actttcttgt
     8461 tcctccctca cttcaaggtt caacagagaa atatttttag aaaagtcttg agatagtttt
     8521 cgtggctcca gagaagctgc cgttttctta aaatatagac cttgaacttg gaccaagtct
     8581 ggagaagtca ggatagattg gttgcgataa atttcctcaa taaccaggta ggactcatat
     8641 aggagagcgt cagccatttc cagcaagcgt tccaagagac ctttaggaag ctgggtcatc
     8701 ttttcccgta aaaaaagaag taattctgct gtagcttggg catctgaaag ggctgtgtgt
     8761 gcgtgtttaa gaggaattcc taattctcga cacaaaatcg gcaagctata tttttccagt
     8821 tcagggaaaa agacctgggc caattcgacc gtatcaacac gagggtttct tagctcatag
     8881 ccttcaaaaa ataaattttc cgccaagaga ttagcatcaa actgaacatt atgggctaca
     8941 aaaatcccat cctccaccaa gtcaaagatt tttctggcaa cttgcgaaaa atcaggtgct
     9001 tgcgccagac gttggtctgt caatcctgtc agttctttga tatgagcatc caagggttca
     9061 tgtggattga catccgtcgt atagtaatcg acgatttctc catcctcaat cacgacaatt
     9121 cccacttgga taattttagc cttactacct gtgctagttg cctctaaatc caccacaaca
     9181 tagcgattac caatcgtttt cattataaaa aattatacca aaaaaagggc catttggcac
     9241 ctgcaaacat aggataattt tcaaactcaa gaacactact tttcttaaaa atcccatcga
     9301 atagagcatt ctagcctgct gattttttta aaatagtgaa gaaatacgaa aaattgagag
     9361 aagaaatgtt tgcatcttcc ttctctcaac gaatcatgta ttttatttaa ccatgtcagg
     9421 atcgtagtca taaaatcctg tatcaaggaa acggttttta gggtgaagtt tacgaacttc
     9481 ttcatccagc aagaaggctt ggtcatggct aaagttgccc tcttgaatca agctacgcgc
     9541 ttggataaag agttttgcaa tctcaacaaa gttctgacca ggagtgtaga gcccttctag
     9601 tttccagcga gtaaagccat gctccaccaa ttctgttaat ttgatcatca aatcaaggtc
     9661 attgttggca aagatatggg tcccatgatt atcttcaaaa atggaatagt ggctctctgg
     9721 atcacttggc tcagccaaga agaggtcacg tttatgcgtc ttttcatcat cgatatgtgt
     9781 aaagttatag tagttttgca agagcggacg tttagaatga tggatgacac tagcaccgta
     9841 aaccaaaact tcagcaggaa tttccaaaat ctctggcatt ttgaaaagtt cagctgatgg
     9901 aatttcacgc gccaaaacag cctcagatgc gccagccttt tgtccccaga agttaatctg
     9961 acgactgcta gttaccatgg ttgaagcatc gtagatggtc ttaaatgaat aaccatcgcg
    10021 gttgactacg taaaagacgc ctgcatcccc aatcgtaata tagtctgtct tgatttcttc
    10081 caagaagtct aagaaaggct tgatacggtc catcatatct tggtgcatga gagcattgac
    10141 cgcaacgatc aattccttac cagcatcatg aaccaactta gcgatttcac gtaattggtc
    10201 ataactaaag gtcgttggca gacgaaggcc aaaatctttc tcaccgacat agatacggtc
    10261 tacgccagct tcgagtagtt gttcaacttg ttcaatactt tcagcagttg ctgtaatgac
    10321 aatcttttcc ataagaaaaa ttataccaca tttctccaaa atcagccatg ctttgaaaat
    10381 gaaaagggac tttattcttt ttgtaacctt tctgtaataa ttctctgccg aaaaaatgat
    10441 aaaataggta tgtactgtta aggagagaat catgcccgta agaaaattac aatcctatga
    10501 ggtagactat caagaagaat taaaccagca gcttcctcat taccaagctt atacacctga
    10561 agcgcaatct gatgccaatc tcaaggaaat cctatttttt attaatatcg ctgttttttg
    10621 tatctgtatt gctatcttta gttttatctt tttagcatta aaattatcaa ctgctcttgc
    10681 ctttgccgca gcaatcggat tcagcttact tgttttaaaa gttcaacggt ctattatcaa
    10741 acgaaaacgt agaagataaa tccaaaatat cgccccaatt ggagcgatat ttttattttt
    10801 tctttttaga tggtgtctga atggcaatct tcacttcaaa gattgttccc ttgggtttat
    10861 tatctttgac agtaacagtt ccttttagag catctacaat ttgcttggct agggataatc
    10921 ctaaaccaaa accacctttt tgccgggttc tagctttgtc tactcgataa aaacggtcaa
    10981 aaattttctt tttatcttct gtcgaaatac cgattccatt atcagaaaca agtaaataaa
    11041 gattgcgatc ggtcgccgag ataagaaaat caatttcacc atcctcctca gtatacttga
    11101 cggcattatc gaaaagaatg gtcatcagtt gtttcagaag aagctgatct gtgacaattg
    11161 ttcgatggat acgattttca aaacggaaga cacgattatt ttccgaagca atcatctcgt
    11221 agtttgtgaa agttgtatta aaaaagctag ttggaacttc tgcaagctcc ggcttaatcc
    11281 catcatctct ccgagctaag ttcagcaagc ttgtcgttaa aaaacgcata tttcggactt
    11341 cttccaaact cgatgcaatg ctttcgctca catccataat ggtagcttct ggcttacgaa
    11401 aaagggtctc taagcgattt tgcaaaactg cgagtggagt tcgtaactca tgactggcat
    11461 tttccacaaa agactgttgc ttctgcatac tctcaagcag gggcctaaca ctgaccctag
    11521 ctagatagag actggcaagt aaagacaaaa tccagaaact agccatcacg accacaatca
    11581 attgctcatg cttttgacta gcctgctcca actgactggt attaatcaag acagcagcat
    11641 actttatatt ggttgaaacc gaactaatat tggtctccat caaaatcaca cgatagattt
    11701 cttcctgccc atagctatta aaaacctgaa tctggtaaat atgtcctagt tctttctttt
    11761 ctaacttaat cttatccaag cccaaaaatc gatttccaga aagaagttga gtaaagtctt
    11821 tatcaaagag aatgacttcc gtattggaac tgacattagg ttttatttct actttactag
    11881 cgtccgccct agcattttct aaatctttaa tctcttctgt tgccctattt atagccagct
    11941 gaataactgc ttgaggattt tcactcagtc catgaagctt atcgtccacc gaagtataaa
    12001 gactcgaatg catgacttgt aaaataatca gagtcattgt agaaaaaatc agggtgaaga
    12061 caccgaagtt gcggataaaa taactaaagt catccgcata ccatgttttt ttaagtttac
    12121 tgaacatctt ttaaaagata cccaacacta cgcaaggttt gcaaattctc tgcaaaagtg
    12181 gttcccttta atttcttacg gacttttgaa acatagactt cgacaaccga aatcgttgta
    12241 tcactatcaa atccccatag acggtcaaaa atctgcgtct taggcaaaat cacattttga
    12301 ttttgaagga aataaactag taaatcgaac tctttcccca gcaattcgac aggagtatct
    12361 tcaactttaa cggtattggt tgataaatta accacgatat tcccataagt caaggtgttt
    12421 tcattaaact tccctgaacg tttgagaagg gcctgaatcc gcattttaag ttcttctagg
    12481 tagaaaggtt tggtcagata atcatccgct cccagttcaa atccatgtcc cttgtcatcc
    12541 aaactttcct tggcagtcat aatcagaact ggtgtcgtaa ttcccttttc acgcaattct
    12601 tttaagactt ggaaaccatt tttttctggc aacatcaaat ccagcaaaat caagtcatag
    12661 acaccactct cagcttcgta gagaccttct tctccatcaa atacctgcat aacatccgca
    12721 aaatcgtcta aaaagtcaaa tactgaattt gacagaccta ggtcatcctc aaccaataag
    12781 atttttatca tgagaaactc ctccttatta aaactattat accaaatttg ccttaaaaaa
    12841 aactcaactc tctgcatttt acatgagata gctgagtttt ctttttattt taggcttatt
    12901 tatgcatttc cgtattgaag aacaactgct tcgactgcag ctttttcacg gctaatcaag
    12961 tcaacacgtg ctgtaatttc cttgattccc ataccgatgt tacggctaag agcaaggtca
    13021 gaaagttgcg gctcaaagaa ctccttgtat tccgccaagc gttgctgagt cttaaataca
    13081 tgagcaggaa ggataacaaa gctatcaaag ctcatatctc ctccaagggc tgccttaatc
    13141 caagcccagt tttcacgcgc ccaagaccaa gctgttttct gagttgcttg atgagctagg
    13201 aattggtaat accaagcaga caagtcctgt ggtttgacca caaatttgtc cttccaagaa
    13261 gtaatcaagt tttggatatt atccgcatct gtactgtatg caagagctgc tgccaactgg
    13321 cgtttaaaga cagcatctgt tgcgtgagta taagtatcaa gataaagtgc taacaagtct
    13381 ttagtctcat gatgtttcat ctcattaatc agaacttgtg agcgaatagc tgctgggagt
    13441 cctgcaagat tctccttgtg tgttgcgaag atttggctag cgacttgact agcttctgca
    13501 tcatttgagc gaatcatcat cgaaacagcc agctgacgaa ccaattcatc ctcatctgat
    13561 tctccgtctt tagcttcaaa accaagacgg tcatagttat gacgagccaa tttagcaacc
    13621 agtcctttga aggctgtttc agcatccgtt ccttcatcaa taaagcgctc aagggctgaa
    13681 atcacttgag aaacagctga aaccaccaga taagactctt ccttagcaag tttatcaaga
    13741 actggaagca agtctgcata agaaatgtgc cctgcctcag ccaacaaacg acgttcttga
    13801 acaatttgca gtttgcttgt gttatcaagt gtctctagct cagcaagaac agcttctaac
    13861 aagtctcctt gatagtcggt aatatagtgg gcagtatttt cagtgttgag acgaagagct
    13921 ccttcatttt cagcaagaag agctgcgtag ccagggattt cgatactttc agtttcgagt
    13981 gtatcaggca agcctttcca gttgctattg aggggcacca cccagagacg gttcttgtct
    14041 tcgttctcac cgatgaagaa ttgtttttgt gaaatcttca agacatcatt ttcaactttg
    14101 acagtaagaa ctgggtaacc aggctgttcc aaccaagaat ccatgaaggc tgcgacatca
    14161 cgtcctgacg cttgaccaag ggcatcccaa aggtcactac caatggtgtt gctgtattgg
    14221 tgtttttcaa agtaggcatg caaaccttta gcaaaatcag catctcctag ccaacggcga
    14281 agcatgtgca tgagacggct tcctttggca tagacgatag cgccgtcaaa gagtgtattg
    14341 atttcatctg gatgtttaac ttcgacgtgg acagactgaa cgccatcagt agcgtcacgt
    14401 tcaagagcaa gaggtactcc acctgtttgg aaatcttcaa agatattcca gcttggttcg
    14461 atggtatcca cacagacgta ttccatcata ttagcgaaac tttcattgag ccaaaggtca
    14521 tcccaccatt tcatagtcac gaggttccca aaccattggt gagccaattc atgggccaca
    14581 acaagggcaa cttgttgacg gctagcaaat gtagagttct catcgacaac caagtaaact
    14641 tcacggtagg tcacaagacc ccagttttcc atagcaccag ctgagaagtc aggaagggcg
    14701 atgtggagag attgaggaat tgggtactta actccatagt aatcttcgta aaactcgata
    14761 gagcgaacag cgatatccag tgagaaatca agatttgaaa gtggatgtgc tttggttgag
    14821 tagacaccta ccagggtacc atttttagtt ttagcggtca ccccttgcaa atcaccagca
    14881 acaaaggcca acaagtaaga agacatgcga ggtgttgtct caaacttcca gatacctgtt
    14941 tccttacggt tttcaacatc gatttctggc atgtttgaca aggccaattc accttctgct
    15001 tggtcaaagc gaagagagag gtcaaaagtt gctttggctt caggctcatc cacacatggg
    15061 aaagcttcgc gcgcaaaatg gctctcgaac tgagtagaca agacctcctt cttgactcca
    15121 tcaactgtat aataagaagg gtaaatccct gtcatgttgt ctgtaatttt accagaaaag
    15181 gcaagaacca attcaacttg accagcctca gccaattcga tatgaagggc ttcattgtca
    15241 tggtcaactg taaatggacg agcttgacct gcaacttcta cagaggtgat ttccaagtct
    15301 ttttggtgga gggagatgcg gtcactctgt gcttgaccag tgatggtcac tttcccagaa
    15361 aaagtcttgg tctcacgact caaatctaaa aataaatcat aatgttcagg aacaaattgc
    15421 ttaataaaat gttcaactgc ttgcatagtt ttctcctatt ctaagtttaa gagctgctgc
    15481 tcttcttcaa acaaacttat tatatcatat tttgcctgag aaaaaaggat tggacagcga
    15541 tttccaaaac tttcttcctt ctaatagtct acagtgggta gaccttgcga aattcttcta
    15601 aaacaacctt gctttcaggt gtaaaagtca atcctgcttc acccaagcag tctctgaaaa
    15661 aatcctcatg aacctggcgc caatagacaa gtgtcttgtt tccctcacct tccttatagg
    15721 catggtcagc tgacactcga ttgaagggtt taacagaaac ctttgtaatt tcgacaatgc
    15781 agacagactg attttgacta tctaaaatga catcgaaggt ccctacttgg ggaagtggtt
    15841 cgtcttctag tacatagagg tcataggctg atgctgttgc tgtcttttct cctttaaaca
    15901 ccaaatccgc taaaaggtct ggttcaactc caaaagccca agcatcgatt tcatctccga
    15961 tcaaaggatt gatttgcttg tatttattcc acatttcttg cggtatcatg ggtactcctt
    16021 tgtaattttt tactttcttc ttttatgtgt ttaagatgat ctggatggtc aatctctaaa
    16081 tcaaaaatct ctggaataga actgtagtgg ataatgcact tgatacccaa ctgattcatt
    16141 ttttgtatga aagaagtatt cagatagcct gctacagcaa aattaatctt gttctttctt
    16201 gctttatcct gcatatctct tagcatatct aacattattg gactttccat atcatgccat
    16261 tgactgtttc tcatagtcgc aaaaacaaag gaagtcaaat cattcattcc aactacaatc
    16321 tttgaaatgc ccgtttccag tatactagat aagtcaaaat acgctgacgg taattcaatc
    16381 atcgttccga ctttcccagt aaagccatac tgacgcaata ctgtaatagc ttgttttaat
    16441 tggtcggcat cattgacaaa aggaaagata agagatagat tgggattggt ttgataaact
    16501 tttgtaacga catgtgcttc agcctgaaat tcatccaaac acgccagtaa acgcctggtt
    16561 cctctatagc caaacaaggg atgcccttcg tcaaaaaact ctctagtccc cactaaacaa
    16621 ttggcctctg tattcgttaa ttcagaaaaa cgataccaaa cttcttcatc tgagtacagg
    16681 gagcagatag tctctagata atcttttaca aattgctgac aacttgctaa tatgatgttt
    16741 tgattaagct ctctcaacaa atattcccca cgaatcatgc cgacgtggtg aaatagttga
    16801 ggataaattt tttcaagaat tttttcgcca ctaagggcaa gttgatttct catcattcac
    16861 cttccaattc atgtaagaag tcttgtccag ttctggaaat cctaataatt cagacttaac
    16921 cttcaagact aatggcgatg cattttcttc tgtaatttct tgaatatcca tccaaatata
    16981 tccaagtgaa tcattcgcac catcagacac agcttccgaa gtcgtaactt gaggtgcact
    17041 ctcattcatt tcaacatcat acaaggccat gacatggtga accataaaat tttttaactc
    17101 ttctctgacg aaaacatcgt agattcgagg attagagtag cttctaacag taaatctcgt
    17161 ctcttccata acttctctag tcagcgtttc cgtcagtcct tcaccaagtt gctgactgcc
    17221 tccaggtaga tcataccgat gttgataagg gcctctcgtt ttttcaatgc aaagtaactt
    17281 tccattttca aagcaaacag cgtagactcc aaagtgtttt ttgatttcca tccaactcct
    17341 cctacttcaa agaccagcca ccatctattg tcaagatttg tccttgcatg gcgctcgctt
    17401 ttccacttgc taaaaaaaga ctaagctctg ctatttcctc tggctcaatc cagcgcttga
    17461 ttggggtttc actagccacc cagtcagcca aaccacctgg ttcaaaatcc gcagcggtca
    17521 tagctgtctt gactgctcct ggagcgatac caaagacctg aatcccagct tcagcatagt
    17581 ctagagccaa ctgcttggtg aagccagcca aggcatgctt ggatgaagta taggcgtgac
    17641 cacctccacc tgctaggcta gaagcaatgg aacacatatt gatgatgatt ccctttttat
    17701 tttccagcat ttgtgtcaaa taataccgag tcaactctac tggaataatg tagttgattt
    17761 caaaaatctc ttgaatgtcc tgcgccgttt gttccaacag tggtttgtaa tcatccaaaa
    17821 ctccagcagt attacacaaa acatccacct gagggcacca gtcaaaaata ggttccaagt
    17881 ccaaggtcaa atctctctgt aaaaagtgaa aatcaccctc taagagtggc ttttcacctt
    17941 ggtcaactcc ataaacttga tagcccttct ctaaaaagag gcgagcttga gccaatccga
    18001 tccctgaact cactcctgta atgagtacac gtttagtcat gcacttctac ccaatccgtt
    18061 gccaaaacat cacaaactgt cgggctccac atggaaaaac cttctccttc gccagaaacg
    18121 ttgattagga aataaggtgt catttcaagt gcaagcccat tttgctcgat ggcatcaaag
    18181 agttggacat agttttccgc acctccccaa ccagttcgta catattttct cttagccttt
    18241 aacccaggca ggatctcttc aaatgtcatg tttttctcct ttaattctac attcttcatt
    18301 taattataac aaaaaaaccg ctttaaaacg gctttttgac tgtgatttat ttacatcttc
    18361 ttctacttac ggcaaattat tccctgcagc aagataaatt tcataccatt cttttcttgt
    18421 taagctaaag tttgccgctt ggctaacttc tctcaagtgc ttaggatttg tggtacctac
    18481 aactgcctgc atttttgctg gataacgcaa tatccaagaa atggcaatag ttgaagaggt
    18541 tactccatat ttaatagcta aacgatcaag tacttgattt aaagcttgaa atttctcatt
    18601 tccaacaaaa ttccctttaa aatacccgaa ttgcaagaca gaccatgctt gaatgaccac
    18661 atcgtgtaat tggcaatatt caaaaatgct gccatctcgc atagctgctt gactatcttc
    18721 catattaaca tgaaaagctg attcaaatcc tggagtaaaa gccgcactca attgtagctg
    18781 attaacagct aacggctgct tgacatcttt tttaagcaac tccatcatca taggattttg
    18841 attagaaact ccaaaatctc gaactttacc ttgtttataa aggagattaa aggcttctgc
    18901 tacttggtca gattccatca aagcatctgg tcgatgaagg agcaagctat ctagatgatc
    18961 aatcttcaat ctttgcaaaa taccgtctac tgattttata atatagtcct tagaaaaatc
    19021 aaaataggta aattcttcaa tgcgaatgcc acatttggac tgaatccaca tcttttctct
    19081 taaatctgga cgatttttta ggacaagacc taacagttct tcacaacgac cacgaccata
    19141 aatatcagcc aagtcgaagg cattgattcc aacagaaagt gctgtttcta caagctcttc
    19201 aacttctttt acagacttat cttttattct catcattccg agaacaattt ctgataattc
    19261 tttgtcatct tgaccaagag ttatgtatct catcaaattt ttctccttta atttctaaca
    19321 ttcttccctt cattataaca aaaaaccgct ttgcaacggc tttttgacta tacttcactc
    19381 cattttatct tcttaaaccc acggaacaag acaaagattc caataaagag gacagctaaa
    19441 ggaataactt ttgtaaggaa aacatttgaa attcccatcc actcataata acggagcaga
    19501 gaacccacca caagatgggc aataatcata ctgacaaatg gacgaaagac cgcttctttc
    19561 caattccaaa taccgataac tagcgaaatc gtaaagacag acaaactatc ccagggagcc
    19621 ggaatataaa aggctccttc ttgtacaaaa cttcctattc ctacatatcc cataacaact
    19681 agcagaacaa gaatcccaac gacaatatag gtgccaattt tcattttagg agaatcttgg
    19741 actaagcacc aacgtaagat tgtggccaca agtccaaatc caatcagaaa aataagaagt
    19801 tgccctaaaa atgtgagcaa attgactgtt aagagaggac ctttagaaaa atcacttagt
    19861 agttgataat aacgtaatac cgctaggata agaattggcg tcaaaaggga ctctttgata
    19921 gaactgcgag gtgctccctt gagaatctct ttcattattt ttttaggatt cttacctaga
    19981 taatcctctg cactcatgcc atctcgttct gcttctgaga aatctagcat catcaaatag
    20041 atctgctctc tgagatagtc ttcatcatag agaaatccag caagattaaa attttcccac
    20101 aactcctcaa aatacttttg attctcctca gaaaactcat gtagcaaagc gcttgtttct
    20161 tcgtaatact tcattttctt catggtttaa cccccattct taatcccttc tactttttga
    20221 ctcaaatcgt cccattgttg ccaaaagact gagacacgct cttctccttc tttcattaat
    20281 gaaaaatact tccgatctgg accatctggc gacgggcgca tgtcgcctct tatccattga
    20341 tttttttcta acttttgcaa caaaggataa atagttcctg gaacgatagt atcaaatcca
    20401 gcctctcgca aagtctgaac caactcataa ccataccgct ctttttgacc aatcatatcc
    20461 aagacacaac cttcaagaac accttttaat agctgagttt ctttcatcac ttctcccttc
    20521 taatctattt tgtaatacct actagtaact tcacctatag tatatcactt ctacactagt
    20581 ttgtaaagca taatagttaa tactcttcga aaatctcttc aaaccacgtc agcgtcgccc
    20641 taccgtatgt atggttactg acttcgtcag tttcatctac aacctcaaaa ca
//
LOCUS       DAVDZK010000040        19305 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVDZK010000040 DAVDZK010000000
VERSION     DAVDZK010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19305
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.041"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..382
                     /locus_tag="VUX16_001738"
     CDS             <1..382
                     /locus_tag="VUX16_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET8124655.1"
                     /translation="KGYEVQLALIATKPELSYLSTLIRYEELYAINPNQARATPKEHH
                     DFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSGEDTTSAATVLHDLLFGEWNTV
                     EKEMLKIGQERLWVINKELNNRGD"
     gene            384..1780
                     /locus_tag="VUX16_001739"
                     /pseudo
     CDS             384..1780
                     /locus_tag="VUX16_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1782..2477
                     /locus_tag="VUX16_001740"
     CDS             1782..2477
                     /locus_tag="VUX16_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124656.1"
                     /translation="MRDIVIKFLQNNHFNQLDTDFDFYTNSQKSEYFIVSQYSPDELN
                     NFFDDDKTSQVIKEFERVSLTPEHENIKKNTSMFILVEVDDLKEVFEDEKVQRSILLI
                     EEDYYYFRKFIILYTRNGLLDLRDKETNEILYTYLESNIDAFEDDMFFSESYFMAMEI
                     GVKLPFFTLPKRNDIYQSIESQYQDDKDELDNRLLDFYTKNTDEKLSKSLKDISTDDD
                     NISDLLQIGELLQ"
     gene            2474..5122
                     /locus_tag="VUX16_001741"
     CDS             2474..5122
                     /locus_tag="VUX16_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET8124657.1"
                     /translation="MKIKKILIKNFKNIKETRIIDFQENVTLFVGPNGFGKTTIFDAI
                     ELSLTGKIRRIEESDYSDGRSSFSAPYFQNNPNQNTFIELMLTNDEGNSLIVSSLYKS
                     SMNTEGSNVPKFSFSKFQRRVRVGPGISFQSDEDFEGSSERDIQKDISQFLGYESEDY
                     SLGDTFDLFHYIQQDETAYYLKQKEKDRKEQLNFLLNIGNYVNRKNRLERLRSTLSSS
                     EKELRAKKGKLKNSPIKNNILYSKLSLRADTDFAFNNKSIIFDEELSNESLNIYLSEI
                     TKLQEFRNSFSPKDYFLRKQSEQFEREVLDDKDFTIYLIVREILENQENIESIKQNYS
                     LISNEKNFSYFLLKNYLERQDLLENDSKLFKFGKRLKSLLDVEIAKIDIKSIENSLNN
                     FTGWEFGRLWIEKFEPKLTEYKFKEGQLDDGTESINKLLEIRTRLKEHSTGNHSECIF
                     CGYDWGESENLLAAYEETTNQLRKNLTNFEIEVSNLVEELNQLKMELQNQIQMEQEKL
                     FVIPDDFLAAIRSISNYNFPESFSNLVVMNSEITPLPVDKSASLQEFENLKTELISSL
                     QEKLLIPNEVYGTFLRVVNKSVDFEKLLEKYSILAGESIREYEISFDLLPISLHKFEE
                     NKDRLLVFLGDLRSQIVFDYSKSLDSQNLFDKYFASKEKTFEDCTIESINQKREYIIN
                     QFELQSLTMFHQIEKRLQIIEQTITYLQDRVRELNNNIKSYQEQMIQKLKLPFYMYTA
                     KILQNYQQGMGVLLTTQNNSNIRFIANSNSEQDVMYQLSSGQVAVISFAFTLALNTTF
                     KISRGFKFLSIDDPIQDMDSMNVYALIDLIRHSLSDYQIIMSTHNDGSAMFIKYKFEL
                     FSDSEISNVGLKNIKNILLLDVEVSS"
     gene            5511..5870
                     /locus_tag="VUX16_001742"
     CDS             5511..5870
                     /locus_tag="VUX16_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124658.1"
                     /translation="MGQEIKLIRKQFRITRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQPLSREFREKYMG"
     gene            5880..6245
                     /locus_tag="VUX16_001743"
     CDS             5880..6245
                     /locus_tag="VUX16_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HET8124659.1"
                     /translation="MVYRYRTNLKKVFLTDPELHQLNERISKSNCQNFSVYARKVLLS
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQVEVKRLNEFHGSY"
     gene            6232..8098
                     /locus_tag="VUX16_001744"
                     /pseudo
     CDS             6232..8098
                     /locus_tag="VUX16_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(8143..8997)
                     /locus_tag="VUX16_001745"
     CDS             complement(8143..8997)
                     /locus_tag="VUX16_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HET8124660.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDGFLVLHNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKVEKWGYYEIILLVNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIGKEEFSNCSYLISKIK
                     TLLDNKLNFYEQPVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGEDKLKLHYTDH
                     FNKLVNKK"
     gene            9077..9139
                     /locus_tag="VUX16_001746"
     CDS             9077..9139
                     /locus_tag="VUX16_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET8124661.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            9220..9762
                     /locus_tag="VUX16_001747"
     CDS             9220..9762
                     /locus_tag="VUX16_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124662.1"
                     /translation="MSLSYYYEINPSTDILKCIEELLYKEDKCFNNILKNWKDIRRNH
                     NDSFPNFWCYGAPGILLARKEIFDKTNIGNNDLSIIENVLTNVEKIRELNLCHGSVGT
                     ISCLDAILKDEENLLIKESIDLYFDNVVSQVIKPELSTDLNTMNTFSFMLGVSGVVYE
                     ISRKQDDRLLNVLLLELKRT"
     gene            9759..10898
                     /locus_tag="VUX16_001748"
     CDS             9759..10898
                     /locus_tag="VUX16_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124663.1"
                     /translation="MMTRKVPNIEQMSQIECGFCCYLSILHFYKSKETLLDLRRDIEK
                     GRDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNK
                     VYIMDPSKGYVNYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKG
                     RLILTLLFSIISYLIILSIPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILAR
                     SMGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVV
                     GGVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSL
                     IYSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSVE"
     gene            10961..11602
                     /locus_tag="VUX16_001749"
     CDS             10961..11602
                     /locus_tag="VUX16_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET8124664.1"
                     /translation="MTIESGQRIALVGQSGSGKSTLLKILLGLYKIDTGKVLFDGINI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
                     QGCTKIIVSHRLSTIKDADIIFVMKGGKIVESGNHKYLMALGGEYYSLYTKRK"
     gene            11615..11785
                     /locus_tag="VUX16_001750"
     CDS             11615..11785
                     /locus_tag="VUX16_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124665.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIFYKNNKN"
     gene            11819..12547
                     /locus_tag="VUX16_001751"
     CDS             11819..12547
                     /locus_tag="VUX16_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET8124666.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            12540..13277
                     /locus_tag="VUX16_001752"
     CDS             12540..13277
                     /locus_tag="VUX16_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124667.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLTTVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            13290..14000
                     /locus_tag="VUX16_001753"
     CDS             13290..14000
                     /locus_tag="VUX16_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124668.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISALYSE
                     LDYNKYWYVLHTLIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIMSFLLFLPIAIFMQICCI
                     RFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSITNLGIKLLVCIWIMG
                     FEFSLLPKLIKLKEQNLV"
     gene            14543..14764
                     /locus_tag="VUX16_001754"
     CDS             14543..14764
                     /locus_tag="VUX16_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8124669.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            15070..15384
                     /locus_tag="VUX16_001755"
     CDS             15070..15384
                     /locus_tag="VUX16_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HET8124670.1"
                     /translation="METVNYKDLVAIGFPEHTSRNIIRQAKKIAVKKFEEARKNDKNE
                     VQLGCSPFDNKRLGIAPKNIVENLISISFSDIEGEKNGYIKDKEISRCIQRFKRKNLF
                     SN"
     gene            15311..16496
                     /locus_tag="VUX16_001756"
                     /pseudo
     CDS             15311..16496
                     /locus_tag="VUX16_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520162.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(16953..18299)
                     /gene="gdhA"
                     /locus_tag="VUX16_001757"
     CDS             complement(16953..18299)
                     /gene="gdhA"
                     /locus_tag="VUX16_001757"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET8124671.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKIYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            18745..19278
                     /locus_tag="VUX16_001758"
                     /pseudo
     CDS             18745..19278
                     /locus_tag="VUX16_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6950 a         2578 c         3418 g         6359 t
ORIGIN      
        1 taagggatat gaagtacaat tagccttgat tgcgacaaag cctgagctgt cctatctgag
       61 cactcttatc cgatacgaag aactgtacgc tatcaatcca aatcaagcac gcgcaactcc
      121 aaaagaacat catgatttca ttgtaaatca tctagttgat aatacacggc aattagaaga
      181 actagctatc tttgaaagaa ttcaaattta ccaacgagat agaagttgtg tatatgattc
      241 aggagaagat acaacttcag cagcaacagt tcttcatgac ttactatttg gagaatggaa
      301 cacggttgaa aaagagatgt tgaagatagg gcaggaacgg ttgtgggtga ttaacaaaga
      361 gttaaataat aggggggatt aagttggcga gttcaaacgt tgaccaaaat aggaatgcaa
      421 caccaagttg gagtggatat atccatcaag ggaaagtagg atttttagta gcgttaagac
      481 aattgaaaaa atgtattgat gataaggcgc ctgattacga gaattatgtg attagatatg
      541 aaaatgctga agattttgat attgttgata acaacgacaa agttatatct aggcatcaag
      601 taaaggcata tatagatggt acgtcaaggg aacaatattt aagatacaaa caagaaaata
      661 ttgtgaggtt gaggataaga gaagtaatca aaagatttgg aaagaaataa ttgatgagga
      721 aggatttcaa atccatcaat ttgatgggca aggacacata ctaactgtag aagttagtcc
      781 tgattcaaga tacttacacg ttattgtagc aataacagat ttcaatttat ctcggtatga
      841 gtatttaaag aaagacggtc gcagaaaaaa atatactgat aataattcat gtattcaact
      901 atatccatac aataaagaga acgatcttta tcattgtcca ctttctcagg atgataataa
      961 tgatacaatt agagattatt gtaaagctga aataaaagaa attttaaaat caaagggtaa
     1021 ttcattgaat gatagtgtct cacatttaga ccaagtatat ctcaggtatg taggttcttt
     1081 attggatcat agcattggac aagaacacag tgagtctggt tttccagaaa tatcctttgg
     1141 agaaatactt tccattattg aaacggaaac ttctgaagat gaagtatatg aaatgaaaaa
     1201 aaatttgacc tataggtggg aaaaatatca tggtgattat gcaagtgaca ttagagagga
     1261 agattttaaa cttatggatg aaataaataa tcatttactg tcattgacta aagatgagtt
     1321 ttatgaattt gtgagaatga tgttaccaca cgaaaattca gatgaaaaat ttttagaatt
     1381 gtttcgtaat gccccaatgg aggatatatt ttatgtatta ctggagaaaa ttaagggatt
     1441 ttcgtttaaa tcttacagtt atttagatga taatgagaag agctatagaa cttcattgat
     1501 tagtattcag gatagacctg ggataattgc aaaaaaaatt caagaaataa ttgacaactc
     1561 agaattttta aaagctactt ttaatcatga tttccttatt aatagagata tagatgagtt
     1621 gcatattggg aatagaattg atgaatttga tggcatgcta gataatagat atcgtgaaga
     1681 atggaataca ggagtacaac ataatatatt taaaccgaat atggaattca ttagcattga
     1741 gaaagtaaaa gaaaagaatt tgagtgtgcc ggaggactaa tatgagagac atcgttataa
     1801 aatttttaca aaataaccat tttaaccagt tggatacaga ttttgatttc tatactaact
     1861 cacaaaaatc agagtatttt attgttagtc aatatagtcc tgatgagcta aataattttt
     1921 tcgatgatga taagacttca caagtaataa aagagtttga aagggtatct ctaacaccag
     1981 aacatgaaaa catcaagaaa aatacttcta tgtttatttt ggtagaagtt gatgacttga
     2041 aggaagtatt tgaagacgag aaagttcaac gatcaatttt attgattgaa gaggactatt
     2101 attattttag aaagttcata atattataca ctcgaaatgg gttattggat ttacgagata
     2161 aagagactaa tgaaatactc tatacttact tagaatctaa tattgatgct tttgaagatg
     2221 atatgttttt tagtgagtcg tattttatgg ctatggaaat tggagtaaaa ctaccatttt
     2281 tcacactccc taaaagaaat gatatttatc aaagtataga aagtcagtat caggatgata
     2341 aggatgaatt agataataga ttattggatt tttatactaa gaacactgat gagaaattat
     2401 caaaatcact aaaagatatt tctaccgatg atgataatat ttctgattta ctacaaatag
     2461 gagaattatt acaatgaaaa tcaaaaaaat tttaataaaa aactttaaaa atataaagga
     2521 aactagaatt attgattttc aagagaatgt aactttgttt gttggaccaa atggatttgg
     2581 aaaaactaca atttttgacg caatagagtt atcattaact gggaaaattc gtcgaattga
     2641 agagtccgat tatagtgacg gtagaagtag ttttagtgct ccatattttc aaaataatcc
     2701 taatcaaaat acattcattg agcttatgtt gacaaatgat gagggtaatt ctttgatagt
     2761 atctagtctt tataagagta gtatgaatac tgagggcagc aatgtaccaa agttttcatt
     2821 ttctaaattt caaagaagag ttcgggttgg tccaggaatt tcatttcaat ctgatgaaga
     2881 ctttgagggt tcgagtgaaa gagatataca aaaggacatt agtcagtttc taggatatga
     2941 atcagaagat tatagcttag gtgatacttt tgatttgttt cattatattc aacaagatga
     3001 aacagcttat tatttgaagc aaaaagaaaa agatagaaag gaacaattga attttctgtt
     3061 aaatattgga aactatgtta ataggaaaaa tagattagag cgtttaagaa gtactttatc
     3121 ctctagtgaa aaggaactaa gagcaaaaaa gggtaaacta aaaaattccc caattaagaa
     3181 caatatccta tattcgaaat tatctcttag agcagatact gactttgctt ttaacaataa
     3241 gtcgattatt tttgatgaag aattgtcaaa tgaaagttta aatatatatc tatcagaaat
     3301 tactaaatta caagaatttc gaaattcatt ttctccaaaa gattacttcc ttagaaaaca
     3361 aagtgagcaa tttgagcgag aggtgctgga tgataaagat tttactattt acttaatagt
     3421 tagagaaata cttgaaaatc aggaaaatat agagtcaatt aaacaaaatt atagtttaat
     3481 ttcaaatgaa aaaaatttct catatttttt acttaaaaac tatcttgaac gacaggactt
     3541 gttggaaaat gatagtaagt tgtttaaatt tggaaaaaga ttgaagagct tacttgatgt
     3601 tgaaattgct aaaattgata tcaaatcaat tgagaattct ttaaataatt ttacaggatg
     3661 ggaatttggc aggctatgga ttgaaaaatt tgaacctaaa ttaacagaat ataagtttaa
     3721 agaagggcag ctagatgatg gaacagagtc gattaacaag ctactcgaga taagaactcg
     3781 tctaaaagaa catagcactg gaaatcattc ggaatgtata ttttgtggtt atgattgggg
     3841 agagagcgag aatttactgg cagcctatga agaaacaacg aatcaactac gtaaaaattt
     3901 gactaatttt gaaatagaag tttcaaattt ggttgaagaa ttaaatcaat taaaaatgga
     3961 gttacaaaat cagatccaaa tggagcaaga gaaactcttt gttattcctg atgatttttt
     4021 ggcggcgata cgatccataa gtaattataa ttttcctgag tcttttagca acttggttgt
     4081 aatgaactca gagattactc ctttgcctgt tgataagagt gcttcgctac aagagtttga
     4141 gaatttgaaa acagagttaa taagttcatt gcaagaaaaa ctattgattc caaatgaagt
     4201 ttatggtact ttccttagag ttgtaaataa gagtgttgat tttgaaaaac ttttagaaaa
     4261 atattctatt ttagctggag aatcaataag ggaatatgaa atttcttttg accttttacc
     4321 catttccttg cataaatttg aagagaacaa agacaggtta ctagtatttt taggggatct
     4381 tagatctcaa atagtatttg attattctaa aagtttagat tcacaaaatc tatttgataa
     4441 atactttgca tctaaggaaa aaacttttga ggactgtact atagaaagta tcaatcaaaa
     4501 gagagaatat attattaacc agtttgaatt acaaagttta acgatgtttc accaaattga
     4561 gaaacgtctt caaatcattg aacaaacgat tacatatctt caggatcgtg ttagggaatt
     4621 aaataataat ataaagtctt accaagaaca gatgattcaa aagttgaagc ttcccttcta
     4681 tatgtacact gctaaaattt tacaaaatta ccaacaagga atgggagttc tactaacaac
     4741 tcaaaacaat tctaatatca ggtttatagc aaatagtaat agtgagcagg atgtgatgta
     4801 tcaattgagt tctggacaag tagctgttat ttcgtttgct ttcactttgg cactaaatac
     4861 tacatttaag atttcaagag ggttcaaatt tttatcaatt gatgatccga ttcaagatat
     4921 ggattctatg aatgtatatg ctttaattga tttaataaga cattcattat cagactatca
     4981 aattattatg tctacacata atgatggtag tgctatgttt ataaaatata aatttgaact
     5041 attttcagat tccgaaatat caaatgtagg gctaaaaaat ataaagaata tcttattatt
     5101 ggatgttgaa gttagcagtt gatgagacta tatatattaa tggaaatata aaaaacatgg
     5161 tttcattaag acggtatttg agagccttgg ctttcttttt tcttaccatc atttttcatg
     5221 ttgtgatact tttttcaaat ttaccttgct atcctaatat cattactaag aaaatcaagc
     5281 cttaattttt cactgggggt ttgggggcgg agccaccaag ttatcttatc gttggctgtc
     5341 aaaactagaa ggttttgaca ggctggcgat atgatttttg ggatattgtg gacacaatat
     5401 ctgagctcgc aaagaccgaa caaggagaga ctgaggtctt taggaatcgt actgacaatg
     5461 tgaggcagcc ttacattgtc agacaagtat aatgttgaaa ggatggtaag atgggacaag
     5521 aaattaagtt aatccgtaag caatttagaa tcacgagaca agaagaaaaa cagataaaag
     5581 aaatgatgag ggaacaaaaa gtggatagtt tctcagaatt tcttcgtcaa aatttattga
     5641 aaaagaatta tcaggataga atttttgaaa gttggttctc cctttggcag tctcaaaagt
     5701 ttgaacagat tagtcgagat gtgtatgaag ttctggttgt cgcaagagaa aatcatcaag
     5761 tgactcaaga gcacgtctca atcttattga cttgcgttca agaattgatt gcagaagtga
     5821 atcaagtaca gccactcagt cgtgagtttc gtgaaaaata tatgggttag gaggatgtaa
     5881 tggtttatcg ctatcgtacc aatctcaaaa aagtatttct aactgatcca gaattacacc
     5941 aattgaatga acggatttct aagagcaatt gtcaaaattt ttcagtctat gccagaaaag
     6001 ttttgcttag tcccaatatg tcatttgtca cgattaacac tgatacttat gaccagttag
     6061 tttttgaatt gagacgtatt ggaaataaca tcaatcaaat tgcgcgtgcg attaatcaaa
     6121 gccatctgat ttctcaggac caattacaag aattgagtaa aggagtcgga gaattaatta
     6181 aggaagtgga caaagaattt caagtggagg tgaaaagact gaatgagttt catggtagtt
     6241 actaaacact ttgcgacgca cggaaaaaaa atatcgtagg cgtttgatta aatatatcct
     6301 caatccagat aaaacagata atctaaaatt agtatctgat tttggcatga gtaattactt
     6361 agattttcct agccatgcag aaatggtaga aatgtacaat gttaacttta ctaataacga
     6421 caagttgtac gagtccagaa atgaccgaca agaaaaacac taacaaacta ttcatgccca
     6481 tcatctcatc caatcatttt ctcctgaaga taatctgaca cctgaagaaa ttaaccgcat
     6541 tggttatgag accatgatgg aattgacagg aggtcgtttt aagtttatcg tagcaactca
     6601 cacagacaaa gatcatgttc ataatcacat cctaatcaac gctattgacc gcaattcaga
     6661 taaaaagttg atatggaact atgccttgga acgaaacctc cgtatgattt cagaccgtat
     6721 ttctaaaatg gctggtgcaa aaattattga gaaacgttat tcctatctag attataaaaa
     6781 atataaggaa tctagtcata aatttgaatt gaaacaacgt ctttattttt tgcttcagca
     6841 atctaaatcg tttgatgatt ttttagagaa agcaaagcag ttgcatgttc agattgattt
     6901 tagtcaaaag catagccgtt ttttgatgac agatagaacg atggtaaaac caattcgagg
     6961 tcgccaactt agtaaacgag atttatatga tgaagacttt tttaaaacat attttgccaa
     7021 acaagagatt gaaagtcgtt taaaattttt actaaagtct gtttattcat tagaagaatt
     7081 gcatgtaaaa gctaaagagt tgaatctaac catcgagtta aaacagaaaa atgtgatgtt
     7141 taccctagaa gaagatggta aaaagataag cctgagtcat aaaaaaatta gcgataagaa
     7201 attgtacgat gttcaatttt ttaatcgtta ttttgaagat agagaagtta gagatattca
     7261 agtattagaa aatcttcagg aagattttca gacttttcga gaggagcagc ataaggagaa
     7321 agtctccgct gaagaaatcg aggaagcctt caagaaatac aaggaaaaac gagatgctat
     7381 ccatgagttt gagattgaac ttacggataa tcagatagag aagttggttg atgatggtgt
     7441 ctatatccag gtttcgtttg gtatcaaaca gagtggactc atctttattc ttaactacca
     7501 gctagatatt tttgaggaag acaatcataa aaaatataaa gtctacattc gagaaacgtc
     7561 ttcttacttt gtctataata aagaaaacat ggataataat tgtttcatca agggtaggac
     7621 cttaatcaga caattgagca acgatagcca aaaactcccc tatagacgac caactttaaa
     7681 aagtcttcaa gagaagattt ctgaaattaa tcttatgatt gaactatcta acacgaacaa
     7741 acaataccaa gaaatcaaag atgagcttgt attagaaatt gcagagattg atatgcagct
     7801 agaagaaacc caagaaaaaa tcgccacctt aaacaagatg gcggaagtac ttatcaattt
     7861 gaagagtgaa gatcatgaga ctagaaaatt agctaagtat gattttgacc aaatgaacat
     7921 gacggaatca ataatgttag atcgactcaa tacagatatt ttaaaattac aacaggaact
     7981 tggtaatgaa attaataaat atgaggagat agctagaaga ttggatttgt ttgtgaaaat
     8041 tattaatacc aataaattta cagttctaaa atttcacgag aatgccttac tagaataata
     8101 ttatttacga ctaattagtt aaaagataga gaataatttc atttattttt tgtttactag
     8161 tttattaaaa tggtcagtat agtgtaattt taacttatct tctcctaaaa tatcgaagac
     8221 ttgtatggct tgtttcattt tttcaattcc actggttgat tggcaacgtt taaattcaaa
     8281 gtaaccagtt gcatagagaa aaactggttg ttcataaaag tttagtttat tatccaacaa
     8341 tgtctttatc ttactaatta aataggagca attagaaaat tcttccttac caatgcttag
     8401 aataaagcaa ttaatagcaa gctgagagac aatctgctta ttagttttat tcagagatga
     8461 gtaaatatag ttatttaaca tctctttagt taataagaag taggagttgt agttaattgt
     8521 gcgtacacag ttaactaata aaatgatttc ataatagccc catttttcaa ctttgaaaag
     8581 atagtctgtc agatgaagaa gctcttcatc tgatggaatg atgttcgaat ccattgtgtg
     8641 taaaatagat tttaccattg ttttctcaaa agaatttaga gtgtaatcag aagtatcaga
     8701 aagtagacat gctatattat tgatactttg tgatgaatat tgcttacgaa tgtactgtac
     8761 tagattagca aatgattcgg aactggtata gtcgtcattg tgtaaaacaa ggaacccatc
     8821 caaagtaata tgtaatttgt ctaaaatatt gattagtcga atacaagata tctctgactc
     8881 cccacgttca aaacgagata tttgtgattt tgaaagatgt tcatctgcta cagagcatag
     8941 actaatttgt tttcctttac gaacttttct aagtgtgatg ccaagttttg atttcataat
     9001 ttcccatttt cccaacaaaa attaaatccg tttttattta ttgtacaata aataaaaacg
     9061 gaaaggaagt ccaagtatga agaaaatttc aaaattttta ccgattttgg ttttggtgat
     9121 ggatattatc atcatttaaa aaagtgtatt aattattgta tttcacaatt agataatata
     9181 acagtaacag gtttagcaca cggttattct ggagtagcaa tgtcattatc atattattat
     9241 gaaattaatc ctagtacaga tatattaaaa tgtatagagg aattactata taaagaagat
     9301 aaatgtttca ataatatatt aaaaaattgg aaagacataa gaagaaatca taatgattcc
     9361 tttcctaatt tttggtgtta tggagctccg ggcattttgt tagctagaaa agaaattttc
     9421 gataaaacta atattgggaa taatgattta tcaataattg aaaatgtatt aactaatgta
     9481 gaaaaaataa gagaattgaa tttatgtcat ggttctgtag gtactatcag ttgtcttgat
     9541 gcaatattga aagatgaaga aaacctatta ataaaagaat ctatagattt gtattttgat
     9601 aatgtcgttt ctcaggttat caaaccagaa ttaagtacgg atttgaatac tatgaataca
     9661 ttttctttta tgctaggagt atctggagtt gtctatgaaa tatctcgaaa acaagatgat
     9721 agattactga atgttttatt actagagtta aagaggacat gatgactaga aaagtaccta
     9781 atattgagca aatgtctcaa atagaatgtg gtttctgttg ctacttgtcc atactacatt
     9841 tctataaaag caaagagaca ttactagatt taagacgtga tatagaaaaa gggagagatg
     9901 gttatagtat aggtgacttg aaacagttat tgaataaacg aaattttgat actggttcat
     9961 atcaagttaa agatgtaaat aaaattagtg aacttccgtt accattaata gcattttggg
    10021 ataatcaaca ttatgtagtt atttacaaag taaaaaagaa taaggtctat ataatggatc
    10081 cttctaaagg atatgtaaat tatgagttta aggagttttc aaaacatttt agtaatatag
    10141 tactgctatc atttcctaac gaaaattacc aatctttgaa gtcacagttt ccttcaccat
    10201 ggataagagt attctctagt ttttcaaagg taaaaggtcg attgattttg acgttgctat
    10261 tttcaataat aagttactta ataatacttt ctataccagt aatgacttca aagtttatta
    10321 attctgcatt aggtaataca ttttcttttc aaacctcgtt tttaatttta ttttctctac
    10381 tttgtttgta ccttatttct atcttggcta ggagtatggg aattctattt tctaatatat
    10441 tttttagtag agatattgaa agttttacat ttaagcattt gcttaaacta ccatatagtt
    10501 tttttgaact cagggcaaaa ggagatattt tatacagaat ttctagtctt agtggtttta
    10561 gggagctatt tactaaccaa gttgttgggg gagtagtaga tattgggact attctaagtg
    10621 ttgtaatata tatgtttctt agttcaaaaa cattatcaat tatagctctt atattgagtt
    10681 taatcaattt tttgtttctg tttagtacta gaaaaataat gtatgatacg gttaatagag
    10741 aattacaaga acaatcattg atttactcag tagaaacaga agcattaaat actatttctt
    10801 caataaaaat atcgggatta gaagatgaaa tatatgaaaa ctggtctaag tatttaaaaa
    10861 atgtattgac aaagtataaa aaacgaagtg tagaatagat attaaggacc tatctttctc
    10921 ttattccaaa gactcagctc ctgtaataga aaatttaaat ttgactattg agtcaggaca
    10981 gagaattgca ctagtcggtc aatcggggtc aggaaaaagt acgttattaa aaatactatt
    11041 aggattatat aagattgata caggaaaagt tttatttgat ggtataaata ttaatcaaat
    11101 agataaaaaa atattaagtc aaaatttagg agtagttcca caagattcgt ttttattgaa
    11161 cagaagtatt cttgataaca taactttaaa gcacgaagtt acttcacaaa agatagagga
    11221 agtttgtaaa gcagttcaaa tctatgatga aatcatggct atgccgatga aatttaatac
    11281 tatcatctca gagatgggtt caaatatttc aggtggtcaa agacaacgga tagcactggc
    11341 acgtgcatta ataaataatc ctagtattgt aattttagat gaagcaacta gtgcattaga
    11401 cactattaat gaggaaagaa taacaaagta tataaaaagt cagggctgta ctaaaataat
    11461 tgtatctcat agattgtcaa cgattaagga tgcggatatt atttttgtaa tgaaaggtgg
    11521 taagattgtt gagtcaggaa atcataagta cttaatggct cttggtggag agtactacag
    11581 cttatataca aaaaggaaat gaggtgtaaa gaaaatgaag aaagtaaatg aatatgtaat
    11641 ttcaacagca gcctcactag gggtgatgat tggaatagta tttgcaattt ttttagattt
    11701 tccagttgaa tatggtattt ctttaggatt gttgaatgga atagtattgg gttcgctgat
    11761 tttttacaaa aacaataaga attaagcaca attttttgct gtaaactaag gagtagagat
    11821 ggctatagtt gaaattataa atctaacaaa aagctttaaa gatattgaag ttattcataa
    11881 cacttcattt tatttaaata agggaaaagt atatggtttt gttggaccaa atggggctgg
    11941 aaaaactaca attatcaaaa tgattctagg gattttaaaa ccagattctg ggaaaataac
    12001 tatttttaat caaaccgtag aacagaattc cgaaaatata ttatctagga taggattagt
    12061 tttgggacct tcattttatg gtcatcttga tgcttataaa aatttgaagt taatagcaaa
    12121 tatgaaaggg cttagtttag atactgaaag acttaatgaa tatctatcaa tggtaggatt
    12181 aaaagatgtt aaaaagaaaa aagtgaaaaa tttttcaatg ggcatgaaac aacgtctaag
    12241 tatagctgca tcattgttag gtagtccaga aatattaatt tgggatgaac caatcaatgg
    12301 acttgatcca cagggtgtaa ttgaaattag aagtttaatc cgttttctac aggagaaaaa
    12361 aggtattaca tttttaatat caagtcatat tcttagtgaa ctggataaag tgatatctga
    12421 tattataatt ataaattatg ggaaagttga attttttggt tcttgccact accttttaca
    12481 aaagtataat tgtcgaaatc tggaagaagc ctacttagct tgtttagctg gaggtgaata
    12541 tgattaaatt agagtttcta aagcagaaaa aaagcatctt atggtttgtt cttatttttc
    12601 caataattct gaatgctttg ttatatatag acttaacttt taggtatcga ggttatttat
    12661 tggtgcatca aaatgaactt gctttatcta attggcagtt aatttttaaa gaacaaacaa
    12721 tattttattt ttctgaacta ttttatttag ttctatcttt aataatttac gaagtgtttg
    12781 cagtagaatt taaaaatgat gcatggttaa ccgtaatttc attgccattt agaaacaagt
    12841 acacaataaa ttctaaatta ctcactacag tggtttacac atttactttt tggttgtctg
    12901 attatattag cttatacgtt attgggaagg ctattgataa cagtttagag attggtttga
    12961 ttttcttttt aaaaacattt accattcaat taatttcctc gttgatgata atgttattat
    13021 attttctaac tttagtactt ataaggaaaa tttctggaat aataccaatt ggtattataa
    13081 tgatgatttt aacaattagc atatactaca acgattataa ttttaagatt tacttaccat
    13141 ttacttatct ttctcatgct tttagagtga ctgaaagtca attttatatg attttactat
    13201 ctaatataat aatcatcgta cttttttata tattaattcg taaattgaac gaaagaagtt
    13261 ttgagatgaa actttaatag gtaataaaaa tgaagttact taaaaatgaa ttgattaaga
    13321 gtaaaatatt tttatttatt attgttgaca tctgtattca gattctagtc attctagcta
    13381 taaaaacata tattttagat atttcggcac tatactcaga gcttgattat aataagtatt
    13441 ggtatgtttt acacacttta atatatatgc caatgatttt tcctatacaa attttgtatc
    13501 aaaatctaag agaggcattg attgaagata ataataatgg ttggaatatc atggtgatta
    13561 acactaataa tctcgtgaaa atcatctata taaaagtaac gataaatatc gtgagatgtt
    13621 ttatttgtta ttttgtttat acaatttttt ctttaattca attaggtggt atgggaactg
    13681 atatgttatt aaccaatata atatttccca atataatgtc atttctttta tttttaccta
    13741 tagctatctt tatgcaaatt tgctgtataa gatttgattc cattttagca aaggccttac
    13801 ctaatatttt gctgatactt attgttttaa tcacgtttca gagtgattgg aatatattta
    13861 tacctgcaac ttattattat acagaaattc agtcaattac aaacttaggt attaaattat
    13921 tagtttgtat ctggattatg ggatttgaat tttcccttct tccaaaacta ataaaattga
    13981 aagaacaaaa tctagtttaa atgttgctcg aaaattaaat aattgaatac gattaacaat
    14041 gaaacaatac aacgtgagtc atgacttcaa agtaattgat tttatgattc tggtttctta
    14101 cgcttaatta agcaagttgt attcacttta tcaaattgtt attactctaa aaagcgtcta
    14161 acagctatag agtgtctgtt tgcttctctt tacttttatt ttaaataatt cattaacctt
    14221 ccgtaagtgc ccaataataa ggtgtgttga agaagtctga gataaaatag ttctcagtca
    14281 caaaaaaaac tatagattcc cattggtgaa cagctccctg tcaagtagac agtaaaataa
    14341 tataaaatct taagcgacct gattcctgaa ttccagtgga gtcaggttgt tttttaaccg
    14401 tctttcttaa tattgtctta cctataatag atatgcttat gaaaagtgtt taataaatta
    14461 attttagttc aaaatgtcca atttggacac tttgaatgat ttcttagttt tatatattat
    14521 acttttctca ggagaaagct agatgtacag acgtttgaga gatttgaggg aagatcacga
    14581 tttgactcaa aaacaaatag ctaaaatact ttcgtttaca aactcagctt atgctaaaat
    14641 tgaacggggt gagcatacgt taacagcaga tgtattggta actctctcaa acttttacga
    14701 tgtcagtaca gactacctat tgggattgac agattttcct gataaaattc gctttagaaa
    14761 ataatctcct caatttcata gagtgtgaaa atgaggggat tttttatttg ttctttgaaa
    14821 attaaatagt tcaaaatggt actttcctca tttgtggagc aaatttgaat ggctcgccat
    14881 gataagagcg attttaaaac catcaataaa atagagcgat actttatatg ccatgataca
    14941 aatgatatac aatgatactt ctgaccgttc aggctgccaa cgtaaaagag cagcaagtga
    15001 aattcttatg atgacttcat cagtcatgcc atggaggtga aaaaatctaa gaaaggaagt
    15061 agtaaaatca tggaaacagt aaactataaa gatttagttg cgattggttt tccagagcac
    15121 acatctagaa atattattag acaagcaaaa aagattgctg taaaaaagtt tgaagaagct
    15181 agaaaaaatg ataagaatga ggtacaatta ggatgttcac ctttcgataa taaaaggtta
    15241 ggcattgctc ctaaaaatat tgtagaaaat ttaattagta tttctttttc agatatagaa
    15301 ggtgagaaaa atggttatat caaagacaaa gaaatatcaa ggtgtataca aagattcaaa
    15361 aggaaaaatt tattttcaaa ttgaattagg agttgatcca ataactggga aaagaattca
    15421 aaagaaagga aggaaaaatc aacagggact accgtttaat tcttttaagg aagcatatga
    15481 agagatactt cgtctaaaac atgaatttgt gaactctact attaataata gttttctaac
    15541 ttttagagag tttatggaag agatttattt aaaatattat caacaaaaag ttcaatctgt
    15601 aacttatcag accgctttac cacatcatca gttatttatt aagcaatttg gtagtaaaaa
    15661 attatcagat attagtacta ttgactgtga aagatttcgc ttagctatta tagacaagta
    15721 ttctagtaat tatgctaaaa atatgtggta gatttaaagc atgtctgggc tatgcagaaa
    15781 gattgggtta tattgataaa gttcctttta aaggattaga taatcctaga ggaaagtacc
    15841 ctgatacaaa attttggaca tttgatgaat ttaagaaggt aataaactct tttgatatta
    15901 gtgagtatga gggactccat aattgcatga cgatctggtt atattttatg actggtttaa
    15961 gagttagtga gggtattgct cttaaatggg aagatattga ttttgaacgt aaatggattc
    16021 atgttcattc gacaattgag aaagataaaa acggtgtatg gtatgttaaa caacaaacaa
    16081 agacagtagc aggggatcgt aaaattgatt tagatgattt tacgattaca atacttaaaa
    16141 aatggcgaga agttcaaatc aagaatgatg ataaagatta tgtaatatca cgttttggtg
    16201 cccccttgtg taagtctaca atttctagga taataaaaag gcatgctaag attactggtg
    16261 taccagaaat tacggggaaa ggattaagac atagtcatgc atcttatctt ataaatgtgt
    16321 tacataagga tactttatat gtttcatatc gattaggaca cgctgataag tcaaccacgt
    16381 tgaatacata tagtcactgg tattattcag gtgattcaac aatttcagaa gagattacaa
    16441 acagtttaga taatcttgga ttatcaattt acctaccaaa ttcctgccag agttgaaaat
    16501 tgaggaatta acccactaat actgggagaa aataggattt gcaaattgtt actcttaaat
    16561 aatagagcaa ctacagtagt agcttaaaaa catgattaaa tcgctatttt taggagtagc
    16621 ggtttttctt tttgtttaat actctttgaa aatcaaattc aaaccacgtc agctttgcct
    16681 tgccgtactc aagtacagcc tgcggctcgc ttcctagttt gctctttgat tttcattgag
    16741 tataaaaagg gtcaagtaag tatagtaaat tgaaataaga tatgaacaaa tcgattagga
    16801 aagtcaaatt aatttctaga aatatgttag aaattggttt gaattccgca atcaatttgt
    16861 tcagttttta tttcatttaa ttagaatttc ccaactgtct aactcaacta aaaatcccca
    16921 atcgtagtga ttgaggatta agcaaataaa tcttaaacaa taccttgggc aatcatagcg
    16981 tttgctacat tttcaaatgc agcaatattt gctcctgcaa gatagtcttt atcaagacca
    17041 tatgtttctg aagttgtttt agctgtgttg aagatgtttg tcatgatgtc tttgagacgt
    17101 ccatcaactt cttcacgagt ccatgagaga cgaaggctat tttggctcat ttcaagggct
    17161 gaaacggcta caccaccagc gttggcagct ttggcaggtc cgtagaagat accattttct
    17221 ttgtagattt tgatggcatc aaggtcgctc ggcatgttgg caccttcaga tacacagata
    17281 acgccttgag caaccaaacg tttagctgct tcaccgttga tttcgttttg agtagcacat
    17341 ggaagcgcaa tatcatagtt tccagcgtaa gtccatacag aaccttcgtg atatgttgca
    17401 gttgctttct cagctgcata ctcagtcaaa cgagcacgac gtttctcttt aacatcaacc
    17461 aaaagatcga agtcgatacc attttcatcg atgacataac cgtttgagtc agatacagag
    17521 atgacagtag cgccaagttc agtcgctttt tgaagagcgt attgagcaac gttcccagaa
    17581 cctgaaataa cgactttctt accagcaaag ctgttgccat ttgccttgag catttcttca
    17641 gtatagtaaa ccaaaccgta accagttgct tctggacgaa tcaagctacc accaaatcca
    17701 agaggtttac cagtcaagac accagcatca aattggttaa ggcgtttgta ttgaccgtaa
    17761 aggtaaccaa tctcacgtcc accaacaccg atatcaccag caggtacgtc aagtgatggt
    17821 ccgatgtgtt tttgcaattc agtcatgaag ctttgacaga aacgcatcac ttcagcatct
    17881 gttttacctt taggatcgaa gtctgatcca cctttacctc caccgattgg aagtccagtc
    17941 aagacgtttt taaagatttg ttcaaatccg aggaatttca agatcccttg gtttacagtt
    18001 gggtggaaac gaagtcctcc tttgtatggt ccaacagctg agttgaattg aacacggtaa
    18061 ccacggttta cttgaatttt tccatcacgg tcaacccaag gaacacggaa agaaattacg
    18121 cgctcaggct cagtaatacg tgccaagata ttttcttcga tatactcagg gtgtttttca
    18181 aatacaggtt ccaaagtgtt gaaaaattct tcaacagctt ggaggaattc agcctcgtgc
    18241 ccgttacgag cttttacagt ttcaaacacg ctttggatat attctttagc agatgtcata
    18301 tcgttctcct tttgttgtca tattttatta catgagctat tatagcagaa tttttttaaa
    18361 ctgtaaagag aaaaacaaaa attttctaaa aattctttca atttgttttt tggtttcggc
    18421 ttttcttgaa ctgataaaaa tcaaaccttt ttcttggaaa tatctttctc aaagagaaaa
    18481 tcttaaagta tgctataaga aaagaaaatg tttagcaatt cagaaatcac ttgttaattt
    18541 atccgtgata tgttagattt gccagtaaaa ctatgatcat tttggaggaa agcaatattt
    18601 acatctcctt attcatggca ggatttttta tacaagtata gatgtcttgc tggagttgaa
    18661 tcatggaacc caagcggtta ttgagattta gaactatcat cagaattttt tcattagact
    18721 tgttcggtaa ccatacagta ctatactatc catgaacaag acctagaaaa agtagcctta
    18781 tttcttaaaa gttttaatag tttaaagcac ttagcacctg tttatattga tgagacagga
    18841 ttcgatactt atttttatcg aaagtatggt tgttctttaa aaggtcagtt aataagaggt
    18901 aaagtatctg gaagaatata tcagaggatt tctttggttg cagggctaac aaatggtgag
    18961 ttaatcgctc caatgactta cgcagagacg atgacgagcg acttttttga agcttggttt
    19021 cagaagtttc tcttaccaac attaaataca ccatcggtta ttattatgga taatgcaaga
    19081 ttccgtagaa tgggtaagct agaagtcttg tgtgaagagt ttgggaataa acttttacct
    19141 ctccttccct actcacctga gtacaatcct attgagaaaa catgggctca tatcaaaaag
    19201 cacctcaaaa gggtattacc aagttgcaat accttttacg aggctctttt gtcccactct
    19261 tgtaaatgtc taagataaga gctatactag gtaaataaaa atctc
//
LOCUS       DAVDZK010000041        18104 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVDZK010000041 DAVDZK010000000
VERSION     DAVDZK010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.042"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            1156..2415
                     /locus_tag="VUX16_001759"
     CDS             1156..2415
                     /locus_tag="VUX16_001759"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET8124672.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2431..2982
                     /locus_tag="VUX16_001760"
     CDS             2431..2982
                     /locus_tag="VUX16_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124673.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICNQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            2975..4252
                     /locus_tag="VUX16_001761"
     CDS             2975..4252
                     /locus_tag="VUX16_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET8124674.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            4268..5128
                     /locus_tag="VUX16_001762"
     CDS             4268..5128
                     /locus_tag="VUX16_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET8124675.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNISKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            5353..5463
                     /locus_tag="VUX16_001763"
                     /pseudo
     CDS             5353..5463
                     /locus_tag="VUX16_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
     gene            5509..6313
                     /locus_tag="VUX16_001764"
                     /pseudo
     CDS             5509..6313
                     /locus_tag="VUX16_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            6505..8796
                     /gene="pcrA"
                     /locus_tag="VUX16_001765"
     CDS             6505..8796
                     /gene="pcrA"
                     /locus_tag="VUX16_001765"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET8124676.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNIWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFFHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANMQDMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            8839..9519
                     /gene="radC"
                     /locus_tag="VUX16_001766"
     CDS             8839..9519
                     /gene="radC"
                     /locus_tag="VUX16_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET8124677.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQVSV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(9516..10205)
                     /locus_tag="VUX16_001767"
     CDS             complement(9516..10205)
                     /locus_tag="VUX16_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET8124678.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGGQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDNVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(10223..10864)
                     /locus_tag="VUX16_001768"
     CDS             complement(10223..10864)
                     /locus_tag="VUX16_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET8124679.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(10947..11153)
                     /locus_tag="VUX16_001769"
     CDS             complement(10947..11153)
                     /locus_tag="VUX16_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET8124680.1"
                     /translation="MFELTYKDCYHVERTLKYEALMLTLSGCVTLPDTLYVTSLTFRG
                     QKVYQGLVEDLYRFLSHADFLHQN"
     gene            complement(11161..11508)
                     /locus_tag="VUX16_001770"
     CDS             complement(11161..11508)
                     /locus_tag="VUX16_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET8124681.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(11513..12628)
                     /locus_tag="VUX16_001771"
     CDS             complement(11513..12628)
                     /locus_tag="VUX16_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET8124682.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQENHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGIVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(12638..13597)
                     /locus_tag="VUX16_001772"
     CDS             complement(12638..13597)
                     /locus_tag="VUX16_001772"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET8124683.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(13710..14279)
                     /locus_tag="VUX16_001773"
     CDS             complement(13710..14279)
                     /locus_tag="VUX16_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET8124684.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            14407..15078
                     /locus_tag="VUX16_001774"
     CDS             14407..15078
                     /locus_tag="VUX16_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET8124685.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            15062..15880
                     /locus_tag="VUX16_001775"
     CDS             15062..15880
                     /locus_tag="VUX16_001775"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET8124686.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINCVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            15877..16773
                     /locus_tag="VUX16_001776"
     CDS             15877..16773
                     /locus_tag="VUX16_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET8124687.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            16817..17791
                     /gene="pta"
                     /locus_tag="VUX16_001777"
     CDS             16817..17791
                     /gene="pta"
                     /locus_tag="VUX16_001777"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET8124688.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         5386 a         3296 c         3950 g         5472 t
ORIGIN      
        1 atttacccac tacaaatatt atagagccaa aaatcccgtg cctcatcaga cacgggattt
       61 tgtggtacga cgggcatgta tagcgaactg aatctggaat agcacagcat atcttctaaa
      121 atatagtaaa atgaaatgag aacaggacaa atcgatttct aacaatgttt tagaagtaga
      181 ggtgtactat tctagtttca atcaactata ttgttataaa ttgatttgaa tttcaaaatt
      241 aaattgtttg attcttattt caatttgtta tagtatatct gatgtcaaag ttctcggcga
      301 gtcaaatagc gattcccaag cctgactatc gtgaggtagc ggattaaaat ggtctgggga
      361 tagaccgttt taagtctgac gctggaaata agaattgtca gaagaaggga tagagaaatc
      421 gtggctctac gaacaggaac gtgataataa ggcgtatata gcggataaga gggcctcaaa
      481 ctctaaagtc caaaaaggta gtcgtaacct atatgcgtaa atcacgagag taattgaatt
      541 cgtactaaga ttttctattt tcactgtaac cttttaacgt ccttatatct tgtatacacg
      601 aggaaagatg tacgacttat cccgtgaggt ctatcactat aaagagaaaa cgacagatag
      661 aagtgatcct gagtcacggt tatctttaaa atagattgtc tgataggacg gtatgtataa
      721 aacgcttctg tgaactgaga gaaggggaga agttcttgct aaaatttagt tgaacagccg
      781 tattccgata cttagataag agatctagtc ttagccccta ctcagtttta ggggataaaa
      841 aaggggcaat agcgattcga gaaagattat actcttcgaa aatctcttca aatcacgtca
      901 atatcgcctt gccgtatgtg taggatactg actacgtcag ttccatctac aacctcaaaa
      961 cagtgttttg agcaacctgc ggttagtttc ctagtttgat ctttgatttt cattgagtat
     1021 tagtaattca gttactaact cgtcaactct gatttatcca ataaaattga aaaggatgga
     1081 aaaaaggata aatttatgat atactttatt ttgaagacct tattagaaat cttgaaagag
     1141 tattgaaaac ttagaatgag aaaaattgtt atcaatggtg gattaccact gcaaggtgaa
     1201 atcactatta gtggtgctaa aaatagtgtc gttgccttaa ttccagctat tatcttggct
     1261 gatgatgtgg tgactttgga ttgcgttcca gatatttcgg atgtagccag tcttgtcgaa
     1321 atcatggaat tgatgggagc tactgttaag cgttatgacg atgtattgga gattgaccca
     1381 agaggtgttc aaaatattcc aatgccttat ggtaaaatta acagtcttcg tgcatcttac
     1441 tatttttatg ggagcctctt aggccgtttt ggtgaagcga cagttggtct accgggagga
     1501 tgtgatcttg gtcctcgtcc gattgactta caccttaagg cgtttgaagc tatgggtgcc
     1561 actgctagct acgagggaga taacatgaag ttatctgcta aagatacagg acttcatggt
     1621 gcaagtattt acatggatac ggttagtgtg ggagcaacga ttaatacgat gattgctgcg
     1681 gttaaagcaa atggtcgtac tattattgaa aatgcagccc gtgaacctga gattattgat
     1741 gtagctactc tcttgaataa tatgggtgcc catatccgtg gggcaggaac taatatcatc
     1801 attattgatg gtgttgaaag attacatggg acacgtcatc aggtgattcc agaccgcatt
     1861 gaagctggaa catatatatc tttagctgct gcagttggta aaggaattcg tataaataat
     1921 gttctttacg aacacctgga agggtttatt gctaagttgg aagaaatggg agtgagaatg
     1981 actgtatctg aagacagcat ttttgtcgag gaacagtcta atttgaaagc aatcaatatt
     2041 aagacagctc cttacccagg ctttgcaact gatttgcaac aaccgcttac ccctctttta
     2101 ctaagagcga atggtcgtgg tacaattgtc gatacgattt acgaaaaacg tgtaaatcat
     2161 gtttttgaac tagcaaagat ggatgcggat atttcgacaa caaatggtca tattttgtac
     2221 acgggtggac gtgatttacg tggggccagt gttaaagcga ccgacttaag agctggggct
     2281 gcactagtca ttgctgggct tatggctgaa ggtaaaactg aaattaccaa tatcgagttt
     2341 atcttacgtg gttattctga tattatcgaa aaattacgta atttaggagc ggatattaga
     2401 cttgttgagg attaaaccgt agaggtgttt atgaatattt ggaccaaatt agcaatgttt
     2461 tctttttttg aaacggatcg cttgtatttg cgtcctttct tttttagtga tagtcaggac
     2521 ttccgcgaga tagcttcaaa tccagaaaat cttcaattta ttttcccaac gcaggcaagt
     2581 ctggaagaaa gtcaatatgc actggccaat tactttatga agtccccttt gggagtgtgg
     2641 gcaatttgta accagaaaaa tcaacaaatg attggttcta ttaaatttga gaagttagat
     2701 gaaatcaaaa aagaagctga gcttggctat tttttgagaa aagatgcttg gtcgcaagga
     2761 tttatgacag aggttgttag aaaaatttgt cagctttctt ttgaggaatt tggcttaaaa
     2821 caattatcta tcattaccca ccttgaaaat gaagctagcc aaagagttgc tcttaagtct
     2881 ggatttagtt tgttccgtca gtttaaggga agtgatcgtt acacaagaaa aatgcgggat
     2941 tatcttgaat ttcggtatgt aaaaggagag ttcaatgagt aagcatcagg aaattctaag
     3001 ctatttggag gaattaccag taggtaaaag ggtcagtgtt cgtagcattt cgaatcatct
     3061 aggagttagt gatggaacag cctatcgggc tattaaagaa gctgaaaacc gtggaattgt
     3121 ggagacccgt cctagaagtg gaacaattcg tgttaaatcc cagaaagttg ctatagagag
     3181 attaacgttt gctgaaattg cagaagtgac ttcttctgag gttctggctg ggcaagaagg
     3241 tttagagaga gaatttagta agttttcaat tggtgccatg actgaacaaa atatcttgtc
     3301 ttaccttcat gatggggggc tcttgattgt cggagaccga acccgtattc agttgctagc
     3361 cttggaaaat gaaaatgcag ttctggttac agggggattt caggttcatg atgatgtgct
     3421 taaactggcc aatcaaaaag ggattcctgt tctaagaagt aagcatgata cctttaccgt
     3481 cgcgaccatg atcaataaag ccttgtcaaa tgtccaaatc aagactgata ttctgacagt
     3541 tgagaaactt tatcgcccta gtcatgagta tggttttctg agagagacag atacagttaa
     3601 agattatttg gacttggttc gtaagaatcg tagcagccgt ttccctgtta tcaatcaaca
     3661 tcaggtcgtt gttggcgttg taaccatgag agacgctggt gataaatcac caagcacgac
     3721 aattgataag gttatgtctc gtagtctatt tttggttgga ttatcgacaa atattgccaa
     3781 tgtgagtcaa cggatgatcg cagaagactt tgaaatggta ccagttgttc gaagcaatca
     3841 aactttgctt ggcgttgtga cgcggcgaga tgtcatggag aagatgagtc gttcccaagt
     3901 ttcggctcta ccaacttttt ctgagcagat tggacaaaag ctctcttatc accatgatga
     3961 agtagtcatt acagtggaac cctttatgct agaaaaaaat ggagttttgg ctaatggtgt
     4021 attggcagaa attctgaccc acatgaccca agatttagtt gttaatagtg gtcgcaatct
     4081 cattatcgag cagatgctga tctacttttt gcaggctgtt cagatagatg atatattgcg
     4141 cattcaggca cggattattc atcatacgag acggtcagct ataattgatt acgatattta
     4201 tcatggtcac cagattgttt caaaagcaaa tgtgactgtt aaaattaatt agaaactagg
     4261 agaaaagatg ataacattaa aatcagctcg tgaaatcgaa gctatggaca aggctggtga
     4321 ttttctagca agtattcata taggcttacg tgatttgatt aagccaggcg tagatatgtg
     4381 ggaagttgaa gaatatgtcc gccgtcgttg taaagaagaa aatttccttc cacttcagat
     4441 tggggttgac ggtgccatga tggactatcc ttatgctacc tgttgctctc ttaacgatga
     4501 agtggctcac gctttccctc gtcattatat cttgaaagat ggtgatttgc tcaaagttga
     4561 tatggttttg ggaggtccca ttgctaaatc tgacctgaat atctcaaaat taaacttcaa
     4621 caatgttgaa caaatgaaaa aatatactca gagctattct ggtggtttag cagactcatg
     4681 ttgggcttat gctgttggta caccgtccga agaagtcaaa aatttgatgg atgtaaccaa
     4741 agaagctatg tacaagggta ttgagcaagc tgttgttgga aatcgtatcg gtgatatcgg
     4801 tgcggctatt caagaatacg ctgaaagtcg tggttacggt gtagtgcgtg atttggttgg
     4861 tcatggtgtt ggcccaacta tgcacgaaga accaatggtt cctaactatg gtattgcagg
     4921 tcgtggactc cgtcttcgtg aaggaatggt cttaaccatt gaaccaatga tcaatacagg
     4981 cgattgggaa attgatacag atatgaaaac tggttgggcg cataagacca ttgacggtgg
     5041 attgtcatgt cagtatgaac accaatttgt cattacgaaa gatggacctg ttatcttgac
     5101 tagccaaggt gaagaaggaa cttattaata aaaagtgaaa agactactgg aagtttattt
     5161 tgataaaaaa tccagtagat cttttcataa taaaacgcat tgtatcaagt gttaggggct
     5221 gatatcatgc gtttttctgc ttttaagatt ttttccaact ctgtttgtaa gcgcatcata
     5281 acaaagggtc taggattcag ggctctcctc ctatatacta ttagtaaagt aaaactaagg
     5341 gaggatattt tagtgtcgca gtctattgtt cctgtagaga ttccacaata ttgtcgtttt
     5401 gattctaaaa agagaaatgg aattctgttt aatgttcgta ttgccaatct taaatttacc
     5461 ttttttagat tagacttcct gcgaaacaaa atatggtata gtagttctat gaattatgaa
     5521 gcaagtaaac aactaactga tgcacgattt aaatgtcttg ttggtgttca gcgcacgact
     5581 tttgaagaga tgttagctgt attaaaaaca gcttatcaac ttaaacacgc aaaaggtgga
     5641 cgaaaaccta aattaagcct agaagacttt cttatggcca ctcttcaata tgtgcgagaa
     5701 taccgcactt atgaacaaat tgcggctgat tttggtattc acgaaagcaa cttaatccgt
     5761 cggagctaat gggttgaagt aactcttgtt caaagtggtg ttacgatttc aagaactcct
     5821 ctcagttctg aggatacggt aatgattgat gcgacggaag tacaaatcaa tcgccctaaa
     5881 aaaagaatta gcgaatgatt ctggtaaaaa gaaatgccac gctatgaagg ctcaagcgat
     5941 tgtcacaagt caagggagaa ttgtttcttt ggatatcgct gtgaactatt gtcatgatat
     6001 gaagttgttc aaaatgagtc gcagaaatat cggataagct ggaaaaatct tggctgacag
     6061 tggttatcaa gggcccatga agatatatcc tcaagcacaa actccacgta aatccagcaa
     6121 actcaagccg ctaacagttg aagataaagc ttataaccat gcgctatcca aggagagaag
     6181 caaggttgag aacatctttg ccaaagtaaa aacgtttaaa atgttttcaa caacttatcg
     6241 aaatcatcgt aaacgcttcg gattacaaat gaatttgatt gctggtatta tcaatcatga
     6301 actaggattc tagttttgca ggaagtctat tgaggtattg agctagttta tgaaaaaatt
     6361 gggtgaaaaa gtcgagtgtt ttagaaaccc acagtgtagt attctagttt caatccacta
     6421 tattttgcta ctccccgtaa agtttctatt ttccctgatt tctgatataa tagaaatatt
     6481 gacttcaaga gtaaggaaga gaagatgaac gcattattaa atggaatgaa tgaccgtcag
     6541 gctgaggcgg tgcaaacgac agaaggtccc ttgctaatca tggcaggggc tggttctgga
     6601 aagactcgtg ttttaaccca ccgtatcgct tatttgattg atgaaaagct ggtcaatcct
     6661 tggaatatct tggccattac ctttaccaac aaggctgcgc gtgagatgaa agagcgtgct
     6721 tatagcctca atccagcgac tcaggactgt ctgattgcga ccttccactc catgtgtgtg
     6781 cgtattttgc gtcgcgatgc ggaccatatt ggctacaatc gtaattttac aattgtggat
     6841 cctggtgaac agcgaacgct catgaaacgt attctcaaac agttgaactt ggatcctaaa
     6901 aaatggaatg aacgaactat tttggggacc atttccaatg ctaagaatga tttgattgat
     6961 gatgttgctt atgctgccca agctggcgat atgtatacgc aaattgtggc ccagtgttat
     7021 acagcctatc aaaaagaact tcgtcagtct gaatccgttg actttgatga tttgattatg
     7081 ctgaccttgc gtctctttga tcaaaatcct gatgttttga cctactacca gcaaaaattc
     7141 caatacatcc acgttgatga gtaccaagat accaaccacg ctcagtacca attggtcaaa
     7201 ctcttggctt cccgttttaa aaatatctgt gtggttgggg atgcagacca gtctatctac
     7261 ggttggcgtg gtgctgatat gcagaatatc ttggactttg aaaaggatta ccccaaagcc
     7321 aaggttgttt tgttggagga aaattaccgc tcaaccaaaa ccattctcca agcggccaac
     7381 gaggttatta aaaacaataa aaatcgccgt cctaaaaata tctggactca aaacgctgat
     7441 ggggagcaaa tcgtttacta tcgtgccgat gatgagctgg atgaggctgt atttgtagcc
     7501 agaaccatcg atgaacttag tcgcagtcaa aacttctttc ataaggattt tgcagttctc
     7561 tatcggacta atgcccagtc ccgtacaatt gaggaagccc tgctcaagtc taacattcct
     7621 tataccatgg ttggcggaac caaattctac agccgtaagg aaattcgcga tattattgct
     7681 tatctcaacc ttattgctaa tttgagtgac aatattagtt ttgagcgtat tatcaacgag
     7741 cctaaacgag gaattggtcc aggtacagtt gagaaaatcc gtgattttgc gaatatgcaa
     7801 gacatgtcca tgctagatgc ttctgctaat attatgttgt ctggtatcaa gggtaaggca
     7861 gcccaatcta tctgggattt tgccaatatg atgcttgatt tgcgggagca gctagaccac
     7921 ttaagcatta cagagttggt tgagtccgtc ctagaaaaaa caggttatgt cgatattctt
     7981 aacgcccaag cgactctaga aagcaaggca cgggttgaaa atatcgaaga gtttctttct
     8041 gttacgaaga actttgatga caccactgat gtgacagaag aggaaactgg tctggacaaa
     8101 ctgagtcgtt tcttaaatga cttggctttg attgccgaca cagattcagg tagtcaggag
     8161 acatcagaag tgaccttgat gaccctgcat gctgccaaag gtctcgaatt tccagttgtc
     8221 tttttgattg ggatggaaga aaatgtcttt ccacttagtc gtgcgactga agatccagat
     8281 gaattagaag aagagcgccg tctagcctat gtaggtatca cgcgtgcaga gaaaattctc
     8341 tatctgacca atgccaactc acgcttgctt tttggtcgta ccaattataa ccgtccgact
     8401 cgttttatta acgaaatcag ttcagacttg cttgagtatc aaggtctggc tcgtcctgca
     8461 aatacaagct ttaaggcatc atatagcagt ggtagtattt cctttggtca aggtatgagt
     8521 ttggctcagg ctcttcaaga ccgtaaacgc ggtgctgccc caaaatcaat ccagtcaagc
     8581 ggtcttccat ttggtcaatt tacagctggc gcaaaaccag catctagcga ggcaaattgg
     8641 tccattggtg atattgctct ccacaagaaa tggggagagg gaaccgttct ggaagtttca
     8701 ggtagcggtg ctaggcagga attgaaaatc aatttcccag aagtaggttt gaaaaaactt
     8761 ttagccagtg tggctccaat tgagaaaaaa atctaatttt ccatccttct cacgaataat
     8821 aaagtgagga ggatttttat gtacagtatt tcattccaag aagattcact attaccaaga
     8881 gaaaggctgg ccaaggaagg agttgaagcg cttagtaacc aagagttgct agctatttta
     8941 ctcaggacag gaacacgtca agttagcgtt tttgaaattg cccaaaaagt cttgaacaat
     9001 ctttcaagcc taacggattt gaaaaaaatg accctgcagg aattgcagag tttgtctggt
     9061 attgggcgtg ttaaggccat agaattacaa gctatgattg aactggggca tcgtattcac
     9121 aaacacgaga ctcttgaaat ggaaagtatt ctcagcagtc aaaagttggc caagaagatg
     9181 cagcaggaat taggggataa aaaacaagag cacctggtgg cactctatct caatactcaa
     9241 aatcaaatca tccatcagca gaccattttt atcggttctg taactcgtag tatcgctgaa
     9301 ccgcgagaga ttcttcacta tgcaatcaag catatggcga cttctcttat cttggtccac
     9361 aatcatcctt caggagcggt agcgcctagc caaaatgatg atcatgtcac taaacttgtt
     9421 aaagaagcct gcgaactgat ggggattgtt ctcttggacc atttgattgt ctctcattct
     9481 aattacttta gttatcgtga aaagacagat ttaatctaaa gttcattaac gacatagtca
     9541 aagagtttct tatctttggg acgattttca aaaagaagtt ctggatgcca ttggacaccg
     9601 agaaaggcga cattatccgt actcatgaca gcctcaatga taccatcttt aggatcatga
     9661 gccacaactt ttaaatttgg tgctaagtcc ttgatgctct ggtggtggaa ggagttgata
     9721 tgagagattt ctccatagat ttcttggaga acggtatctg gttctgttac caagcgttga
     9781 gttgtgtact caacagaaga atcctgccaa tggtcttcga tatcttggta caaagttcca
     9841 cccatggcaa cgttaaagag ttgggtacca cggcagacag agaaaatggg ctttttctgt
     9901 ttaatagctt ccttgatgag ggccagttcg aagatatctc tttgaaggtg atagtcatcg
     9961 ctatcaatgg ttttgggttc gccatagaat tttggatcga cattttgtcc acctgtcaag
    10021 atgagcttgt caatcaaact gatatagtgg caggccattt cttgaccacc aatcggtagg
    10081 atgatgggaa tccctccagc atctttaacg ccttcaacaa agccttttgc tgcgtagctc
    10141 atcatgatgt catcatctgg atgagctttt tcgtttcctg taatcccaat aactggtttt
    10201 ttcataaaat gattttcgct ttctaatcct cttttcgcat gaagtagagg agggtttgga
    10261 gttcacttgt caaatcgaca tactgaacga ccacgtcttt tggtaaatgc agatggactg
    10321 gtgaaaaact gagaattcct ttcacaccag catcaaccaa gagattagca acttcttgtg
    10381 acttgacgct gggaacagtt aggatagcag tcttcacatc agcatccttg attttatcct
    10441 tgatctgaga aatcccgtaa atgggaatcc cgtcaggagt ttgggtaccg acttcaggat
    10501 ggtcatctag gtcaaaggcc atgataatct tcatcttgtt acgttcgtgg aagcggtagt
    10561 ggagaagggc atggcccata tttccaatac caaccagcat gacattggtg atggagttat
    10621 cattgagcaa atcggcaaaa aatgtcatta gttttttgac atcatagcca aaaccacgcc
    10681 gaccaagttc accaaaatag gaaaaatcac gacgtacggt cgctgaatca atcccaatgg
    10741 cctctgcaat ttgcttagag ttggcacgtt caatcttttc tgcatgaaat ctcttaaaaa
    10801 ttcgatagta gagagagagt ctttttgctg tagcttttgg aatagcaaac tgtttatctt
    10861 tcacaaaatc acaacctttc tattcttcta ttttatagaa atattgtgaa aaaatcaaca
    10921 aaaataagaa aaaactaaga aaaatcttag ttttgatgta aaaaatctgc atgagataga
    10981 aaacggtaga ggtcttcgac cagaccctga taaactttct gacccctaaa agtcagagaa
    11041 gtcacataaa gtgtatctgg taaggttaca catcctgaca aagtcaacat gagagcctca
    11101 tacttgagag tacgctctac atgatagcag tccttatagg tcagttcaaa cattttggct
    11161 ctatctttcc gattttgtaa agacaccacg ttctaccaag ctatccatga ggaagtagaa
    11221 tttttcctga tgaatgtggt ggtcttctga tttgaaaata tcaactagac gaaggccaaa
    11281 cttgtcagtg atattgattt tagcccctgt aagttccttg ttaatgatga ttttgagttg
    11341 gaagccttca ccgctgtttg gcactttttc caaaaggcga gtcagttcat agttaccaac
    11401 cttagtttca aaaaaggtgt tatctttgag ggtgaatttt ttaacagaag ggctaagagt
    11461 gtaatcgtaa cgacaatttt ttaactgaat gattttttca aatgccatat ggctaacctc
    11521 cgataatttc ttttaaggtt tttgcgaggg tttgtaggtc ttcaacggta ttttgtggcg
    11581 acaaactgat gcgaagggat tccttcaagc gttctgaatt tgcgccatac atggcttcaa
    11641 gaacatggct ggattggaca atgcctgcag tacaggctga gccagtagag attgaaattc
    11701 cagctaaatc tagccgaagg agtaagaggt catttttctg accaggaaat ccaatattga
    11761 gaacataagg gagatgatgt tttcctctat tcaagtaata ctgaattccc tccagctctg
    11821 ccagaaaggc agtttctaga ttttgtacat gttgaaaatg ttcttcttgt ttttctaggt
    11881 cttcttttag ggctgcaacc atgcctacaa tggcaggcag attttcagtt cctgcacgtt
    11941 ttttctgttc ctggtctccg ccatgtagat aggaatcaaa gtccatgcta gatgcgtaga
    12001 gaaaaccgat tcccttagga ccatggaatt tgtgggcaga agcagtgaga aaatcaatgc
    12061 ccaattcttc tgaatgaatt gggattttac caatagcctg aactgcatca acatgatagg
    12121 cagcagggtg ttgcttgagt atttggccaa tttcagcgat gggcagtagg tttcctgtct
    12181 cattattggc aaacatggtg gaaaccaaaa tcgtatcgtc acgtaaagcc ttttgaattt
    12241 gctgggctgt gatttcttga ttttctggct ggataatggt tgcttcaaac ccaaagtgtt
    12301 gaaccaagta atcaattgtt tcaaggacag catggtgctc gatggcagtt gtgatgatat
    12361 gttttccttg ttcttggtga cgaagacagt agccaatgat ggtagtatta ttgccttcag
    12421 tcccaccaga agtgaaaaag atatgttgag gttttgtcct tagtaactgg gctagttcct
    12481 gacgggcttc tcgcaagagt ttgccagctt gacgaccatg accatgaata ctagaaggat
    12541 ttccgtggtt ttcttgcata accttggtca tagctgaaat agcaactgct gacataggag
    12601 tcgttgcagc attgtccaaa taaatcaaag aatcacctta tttcttttta ttgtaggcaa
    12661 agagtgggct gactggtttt ctttcgtgaa tacggacgat agcatcacca attaactcac
    12721 tagcagtgat atagcataca tttttaggag ttttttcttt tgttgctact gaatcagtca
    12781 caagaatttc tttaatatta gtattgtcaa gaagctcagc agctccctcg acgaagagac
    12841 cgtggctaga aacagcataa atttctgtag ctccttcacg ttcaacgatt ttagaagctt
    12901 cagagaaggt acgtcctgta tttaaaatat catcaatcaa gatagctttc ttaccttcaa
    12961 catcaccaat aatataacct tcgttacgag ttgcatcgtc ttgagggtag tcgataatgg
    13021 cgataggagc atcaagatat tcagccaggc tacgcgcacg tttgacacct gaatttttag
    13081 ggctaacgac aacaacatct gaaccaagca atcctttatc gcagtaatgt tttgcgaata
    13141 ggggaacagt gaaaagatta tccactggaa tatcaaagaa accttgaacc tgaacggcat
    13201 gcaaatcaag agtcaggata cgatcaactc cagccttaac cagcatattg gcaactagtt
    13261 ttgctgtaag tggctcacga ggacaagcaa tgcggtcttg acgtgcatag ccaaaatatg
    13321 gaaggacaac gttgatactg tgggcacttg cacgcacaca agcatcgacc atgattaaca
    13381 attccattag gtggttgttg acagggaaac ttgttgattg gatgatgtaa acatcataac
    13441 cacggacact ttcttcgata tttacttgga tttctccgtc tgaaaattga cgtgatgata
    13501 gttttccaag tgggacacca acagcttggg caattttttg tgcaatctct tggttagagt
    13561 tgagtgcgaa aagtttcatg ttttttctat ctgacattat agaccgtcct ctgtaaactt
    13621 tataaatcct agttatattt accttacata tatgaactgg gatttgtgta tttttatctt
    13681 ttctatttta ccaaaaaatg gagattattt cagctatttt tcatactttt gacaaatcga
    13741 accaattttg aaggagcttt ttggtaggaa atctgatttt tctctaaaaa ttgtcggaaa
    13801 tcctgtttgc cttgctcatg attttccact tcaagctcca attcgtaatc tgtcatatca
    13861 aagtatcggc tctgatccag tgccatgaga ccaatagctg ttttcatttc atagcgaagc
    13921 gttgttagac aaccaagaac ctgccagttc ttactttgga taccatgttt cgccaattca
    13981 tccagtacta gcccttgagg aagttcttcc ttactcagat agttctcagc atcttttagt
    14041 tgcaattttt ggttgtattc catgtttcca acactctgcg ggactttgag tgtcaactca
    14101 gcccagtctt caaaggttcg aatgcgcata gcgactttct tttctcgcag ttcaaaatca
    14161 ggcgtgtcta tgtagtaatt tgtttgaaga acaggagtga cacctgtgaa ctggtctttt
    14221 agacgattgt attcatcttt tttcaatagt gttttcaatt caatttctaa atgtttcatt
    14281 tttcttacct ttttttatcg ttgaaagcgg atttatggta taataagcat tgtatttatt
    14341 gtatatgaat ctggagaaaa aatcaaagat atttttgacg gataatatga gaacaaggga
    14401 gaatatatga ccttagaatg ggaagaattt ctagatcctt acattcaagc tgttggtgag
    14461 ttaaagatta aacttcgtgg tattcgtaag caatatcgta agcaaaataa gcattctcca
    14521 attgagtttg tgaccggtcg agttaagcca attgagagca tcaaagaaaa aatggctcgt
    14581 cgtggcatta cttatgcgac cttggaacac gatttgcagg atattgctgg cttacgtgtg
    14641 atggttcagt ttgtagatga cgtcaaggaa gtagtggata ttttgcacaa gcgtcaggat
    14701 atgcgaatca tacaggagcg agattacatt actcatagaa aagcatcagg ctatcgttcc
    14761 tatcatgtgg tagtagaata tacggttgat accatcaatg gagttaagac tattttggca
    14821 gaaattcaaa ttcgtacttt ggccatgaat ttctgggcaa cgatagaaca ttctctcaac
    14881 tacaagtacc aaggggattt cccagatgag attaagaagc gactggaaat tacagctaga
    14941 atcgcccatc agttggatga agaaatgggt gaaattcgtg atgatatcca agaagcccag
    15001 gcactttttg atcctttgag tagaaaatta aatgacggtg taggaaacag tgacgataca
    15061 gatgaagaat acaggtaaac gaattgatct gatagccaat agaaaaccgc agagtcaaag
    15121 ggttttgtat gaattgcgag atcgtttgaa gagaaatcag tttatactca atgataccaa
    15181 tccggatatt gtcatttcca ttggcgggga tggtatgctc ttgtcggcct ttcataagta
    15241 cgaaaatcag cttgacaagg tccgctttat cggtcttcat actggacatt tgggcttcta
    15301 tacagattat cgtgattttg agttggacaa gctagtgact aatttgcagc tagatactgg
    15361 ggcaagggtt tcttaccctg ttctgaatgt gaaggtcttt cttgaaaatg gtgaagttaa
    15421 gattttcaga gcactcaacg aagccagcat ccgcaggtct gatcgaacca tggtggcaga
    15481 tattgtaata aattgtgttc cctttgaacg ttttcgtgga gacgggctaa cagtttcgac
    15541 accgactggt agtactgcct ataacaagtc tcttggcggt gctgttttac accctaccat
    15601 tgaagctttg caattaacgg aaattgccag ccttaataat cgtgtttatc gaacactggg
    15661 ctcttccatt attgtgccta agaaggataa gattgaactt attccaacaa gaaatgatta
    15721 tcatactatt tcggttgaca atagcgttta ttctttccgt aatattgagc gtattgagta
    15781 tcaaatcgac catcataaga ttcactttgt cgcgactcct agccatacca gtttctggaa
    15841 ccgtgttaag gatgccttta tcggtgaggt ggatgaatga ggtttgaatt tatcgcagat
    15901 gaacatgtca aggttaagac ctttttaaaa aagcacgagg tttctaaggg attgctggcc
    15961 aagattaagt ttcgaggtgg agctattctg gtcaataatc aaccgcaaaa tgcaacgtat
    16021 ctattggacg ttggagacta cgttaccatt tacattcccg ctgaggaagg ctttgaaacc
    16081 ttggaggcta ttgagcatcc attagatatt ctctatgagg atgaccactt tctagtcttg
    16141 aataaaccct atggagtggc ttctattcct agtgtcaatc actctaatac cattgccaat
    16201 tttatcaagg gttactatgt caagcaaaat tatgaaaatc agcaggttca cattgttacc
    16261 agactagata gggacacttc tggcttgatg ctctttgcca agcacggtta tgcccatgca
    16321 cgattagaca agcagttgca gaagaaatct atcgagaaac gctactttgc tttggttaag
    16381 ggagatggac atttggagcc agaaggggaa attattgctc cgattgcgcg tgatgaagat
    16441 tccattatta ccagacgagt ggctaaaggc ggaaagtatg cccatacttc atacaagatt
    16501 gtagcttctt atggaaatat tcacttggtc tatattcacc tgcacactgg tcgaacccat
    16561 caaatccgag tccatttttc tcatatcggt tttcctttgc tgggagatga tttgtatggt
    16621 ggtagtctgg aagatggtat tcaacgtcag gctctgcatt gccattacct atccttttat
    16681 catccatttt tagagcaaga cttgcagtta gaaagtccct tgccggatga tttcagtaac
    16741 cttattaccc agttatcaac taatactcta taaaaactgt ctcagagtat aattattatc
    16801 ttaaaggaga aaactcatgg aagtttttga aagtctcaaa gccaaccttg ttggtaaaaa
    16861 tgctcgtatc gttctccctg aaggggaaga gcctcgtatt cttcaagcaa caaaacgctt
    16921 agtaaaagaa acagaagtga ttcctgtttt gcttggaaat cctgaaaaaa ttaaaattta
    16981 tcttgaaatt gaaggaatca tggatggtta tgaggtcatc gaccctcaac attatcctca
    17041 atttgaagaa atggtttctg ccttggtgga gcgtcgcaag ggcaaaatga ctgaagaaga
    17101 tgtacgcaag gttttggttg aagatgtcaa ctactttggt gtgatgttgg tttacttggg
    17161 cttggttgat ggaatggtgt caggagcgat tcactcaaca gcttcaacag ttcgcccagc
    17221 tctacaaatc atcaaaactc gtccaaatgt aactcgtact tcaggagcct tcctcatggt
    17281 tcgtggtacg gaacgttacc tatttggaga ctgtgccatt aacatcaatc cagatgcaga
    17341 agccttggct gaaattgcca tcaactcagc aatcacagct aagatgtttg gcatcgaacc
    17401 taaaattgcc atgttgagct attctactaa aggttcaggg tttggtgaaa gcgttgataa
    17461 ggtcgttgaa gcaactaaaa ttgctcacga cttgcgtcct gaccttgaaa tcgatggtga
    17521 gttgcaattt gatgcggcct ttgttcccga aactgcagct ctgaaagctc ctggaagtac
    17581 ggtagctggt caagcaaatg tcttcatctt cccaggtatc gaggcaggaa atattggtta
    17641 caagatggct gaacgtcttg gtggttttgc agctgtagga cctgttttgc aaggtttgaa
    17701 caaaccagtt aacgaccttt ctcgtggatg taatgcagat gatgtttaca agttaaccct
    17761 tatcacagca gctcaagcag ttcatcaata gtgaaaacta taaagcgata tactatgcta
    17821 tactgtagtt atgaaactat gtacgaaaag cactgccatt aattcctgag aactaaatta
    17881 ctgattggtg tcaaaaagga aaacttccaa gcgatgatat cctgtctata cacgacctat
    17941 agaaatctgt aatatacatg tccgtaaaac gataaattcc ctttttgatt ttaaatgagt
    18001 atgaaaagag aattttttca tgagaaaacg cataatattg agtgctttga cacctgctat
    18061 tatgcgtttt ctggctcttt gtcaactgta gtgggttgaa gtca
//
LOCUS       DAVDZK010000042        17957 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVDZK010000042 DAVDZK010000000
VERSION     DAVDZK010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17957
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.043"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            253..2932
                     /locus_tag="VUX16_001778"
                     /pseudo
     CDS             253..2932
                     /locus_tag="VUX16_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            3231..4070
                     /locus_tag="VUX16_001779"
     CDS             3231..4070
                     /locus_tag="VUX16_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET8124689.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            4088..5926
                     /locus_tag="VUX16_001780"
     CDS             4088..5926
                     /locus_tag="VUX16_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET8124690.1"
                     /translation="MSYKDKVQKIFDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQSTLVLLVSSCIALVVVGPIGVIVGQGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALFAGITEPAVYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            5939..7354
                     /locus_tag="VUX16_001781"
     CDS             5939..7354
                     /locus_tag="VUX16_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET8124691.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            7946..8992
                     /gene="pheS"
                     /locus_tag="VUX16_001782"
     CDS             7946..8992
                     /gene="pheS"
                     /locus_tag="VUX16_001782"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET8124692.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            8992..9501
                     /locus_tag="VUX16_001783"
     CDS             8992..9501
                     /locus_tag="VUX16_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124693.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            9578..11983
                     /locus_tag="VUX16_001784"
     CDS             9578..11983
                     /locus_tag="VUX16_001784"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET8124694.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNIGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLVDVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDCLPTSLPKDDGTAGELTATQKLRRQVRTIAE
                     GAGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(12051..12818)
                     /locus_tag="VUX16_001785"
     CDS             complement(12051..12818)
                     /locus_tag="VUX16_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET8124695.1"
                     /translation="MLLLSLILLLFGTDKTLSSASNKTKTLKLVTWNVANQIEAQHIE
                     RIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGLSMANYDIFTSPPTNNGIAPV
                     TVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDIIALHTAPPLPGLMEIWKQDLN
                     IIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDALNALPPFERGTWNSQSPKLFN
                     ATIDHILLPKNHYYVRDLDIVSFQNSDHRCIFTEITF"
     gene            complement(12844..13053)
                     /locus_tag="VUX16_001786"
     CDS             complement(12844..13053)
                     /locus_tag="VUX16_001786"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124696.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFPIFLQEK"
     gene            13208..13696
                     /locus_tag="VUX16_001787"
                     /pseudo
     CDS             13208..13696
                     /locus_tag="VUX16_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            13780..14046
                     /locus_tag="VUX16_001788"
     CDS             13780..14046
                     /locus_tag="VUX16_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8124697.1"
                     /translation="MEGCPSEFFSKEEILESDMRVAIMSELIEARHEQGISQKKLEEF
                     SGVSQPVIARMETGKTSPQLDTVLKVLSSLGKTLVVVSLEQRKS"
     gene            14414..16663
                     /gene="metE"
                     /locus_tag="VUX16_001789"
     CDS             14414..16663
                     /gene="metE"
                     /locus_tag="VUX16_001789"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET8124698.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEILEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLNLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVATYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            16727..17593
                     /gene="metF"
                     /locus_tag="VUX16_001790"
     CDS             16727..17593
                     /gene="metF"
                     /locus_tag="VUX16_001790"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET8124699.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPYFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
BASE COUNT         5645 a         3071 c         3843 g         5398 t
ORIGIN      
        1 tttcataata aaaacacccc aaaagttaga ttttttctgt ctaacttttg gggtgtagtt
       61 catgtacacc tgatatgatg cgttttttga attttataga ctgctcgttt aaactctatt
      121 tacctcgtac attccggagc gagatggact attggtcgca tacaaaatga gtgttattcg
      181 gattttattt tcgtgtacaa tttcagctat tcttgttata atcagcctat aggaatcaag
      241 gaggtgactc ttatggctgt ttttgtgtct ttggatggaa ttgtggtaga agtacttgat
      301 gtcttttctt cttttaatgg ggatagtgag tttttcttgt gtaaacgtct taaagacaag
      361 agtcagtttg ttatggaacg ctctcagttc gaggagatgt tccaacttca aagtagtcgc
      421 ttgacgacgc aagaaaaatt acaattgttt acctctgtgt ttgctggccg ttatgatgtt
      481 tatgctaaga gttttatcaa tgatcaaggg aaaattcagt attttccttc ctatgattat
      541 ggttggaagc agttgctatc tgaaaaacgg agtttccaga cattgacgga ttccgttttg
      601 aaatctcatt ttcgtgggga gacagctatc ggtatctttc ctatgcactt agatgatagc
      661 tgtcattttt tggtactgga ttttgatgaa ggagattgga aagaagctgg tttaaccatt
      721 cgaagaatag ccagggaacg ccagatggaa gcccatttag agatttctcg ttcgggtcac
      781 ggactccata tttggttctt ctttgaggaa gcgattccga gtcgagaggc tcgcttgttt
      841 ggaaagaaac tgatagaact ggcaatgcag gaaagtatgc aactgtcctt tgattctttt
      901 gatcgcatgt ttccaaatca ggatgtcctt cctaaggggg ggatttggaa atttgattgc
      961 cttgcctttt caaggagaag cttaccatca agggcgaacg gtctttgtgg atgaacagtt
     1021 tcagccttat gaagaccaat ggaggtatct acaagaaatt cagagggttt caactgctaa
     1081 agtggcactg ttaatccaag aagagttagg caagcaagaa ttggacaagg agttgaagat
     1141 cgtcttatcc aatatgatcc aacttgaaaa atcgtctgtg acacccaaga cactgttttt
     1201 cttgaaaaat atggcttcat tttctaatcc cgaattttat ttaaagcagg ctatgcgaca
     1261 gccaacctat caaattcctg agagaatgta tttatttgga gaatccgatc attatttatg
     1321 gttgccaaga ggtttgctgt atccattgca agataaattt aagcaggtat ctgtggaaga
     1381 taggagaaag gtacaaaggt ctattagcgt ggaatttaag ggagaactca cttttgagca
     1441 agagttagcc ctgtcagata tgacttctaa agaaaatggt ttacttcatg cggagactgg
     1501 ttttgggaag accgttttag gtgctgctct tatctctgaa cggaaaacaa aaacaattat
     1561 tctagtccat aataagcaac tcttagacca atggctagat cgcttaaact gctttttgac
     1621 tttcgaagag gaggaggcta tccgttatac ggcatcaggt cgtgaaaagg taatcggcta
     1681 tgttggacag tacggtggga ctaagaaatg gcttagtaaa ctggttgatg tcgttatgat
     1741 tcaatctcta tttaagttgg aaaatagtca aagtcttttg gatgagtatg agatgatgat
     1801 tgtggatgag tgtcatcatg tctctgcctt gatgtttgaa aaagttgttg ctcagtttag
     1861 agggaagtat ctttacggtt tgacggctac gcctgagcgt aagaatggtc atgagcctat
     1921 tgtttttcag agaattggtg agatactcca tactgctgat aagagggaaa cggattttaa
     1981 acggcaattg caattaagat tcacttcttt tggtcatttg gagattgaaa agaccaaagc
     2041 aagtaatttt atacagctta gtgattggat tgctactgac tcagcgagga atcagttgat
     2101 tctcaaggat attctagccc aagtggcaga aggacggaat atcttggttt tagttaatcg
     2161 aattcaacag atagatgtct ttgaaaagtt attgaaagag aaagaggttg atgactgtta
     2221 cattattagc ggaaaaacca aagtccgaga aagaacgagt ttactggaga cgttagaaca
     2281 gttagataaa gggtttgttt tgttgtctac tggaaaatac attggcgaag gttttgactt
     2341 acctcagttg gacacgctta tcttggcagc acccttttct tggaaaaata atttaattca
     2401 gtatgcaggt cggattcata gaaactacaa ggataagtct ttggtgcgta ttttcgatta
     2461 tgtggatatt catgttcctt atttagaaaa gatgtttcag aaacgacaag tagcttatcg
     2521 aaagatggat tatcgtgtca tcgagggtga ggagaaacaa ttcgtttatg ttgatagtag
     2581 atatgagaag gtgttgagag aggacttagc aggggaaaga caggaatgtc tgcttatttt
     2641 accttatgtg caccagacaa aactgatgaa ttttctaaaa gaatttagga ttagtcaaat
     2701 tgagatatgt ataccagaga cggttgcaaa taaagcatgg ctagaccagt tgaagagcaa
     2761 gaaaattaaa gtatctttta ctcaaataaa aatagtcatg cctattcttt tggtgaataa
     2821 gactattgtt tggtatggcg caatgccatt attagggaag gtagatgaaa tgaccatact
     2881 acgtttggaa tcagctagta tagcttctga actagtggca ggtttacgat agagaaaatt
     2941 tttaaaaatt tctatgtatg attttcattt ctttagtgag actgttgcca ttatcacatt
     3001 cgaatcacac aaaataaaaa aatttctaca agtacttgac aaatagattg aaatatcata
     3061 aaatgaaaat ggttacagag ttattaatga tttaagcttc atgtcaccat taaaaattga
     3121 aataaaagga tgttatcact aatacaagtg agcaggaacc tatttaatca catcggaaga
     3181 agtttcttga tgtttttaag taggttcctt ttattttaaa agggaaattt atgatcataa
     3241 aacgaatact aaaccacaat gccgtaattg cgcaaagtaa aaaagatatc gatattcttc
     3301 tttttggaag gggaatagct tttggaagaa aaactggaga taaagtaaat ccaattgata
     3361 ttgagaaaag tttttttctc aaaaatagag ataatatgac ccgttttaca gagatgttta
     3421 ttaacgttcc tttggagttg gtgtacatca ccgaaaaaat aattaatcta ggtaaaataa
     3481 cattaggtaa taattttgat gagattatct atataaatct aacggatcat atttcttcga
     3541 gtatagaacg ttataaagaa ggagttatta tttcgaatcc cctacgctgg gaaatctcga
     3601 aatattataa agaagaattt gagcttggga aaagggcttt acaaataata aaaaaagagt
     3661 taggtattga acttccaatt gacgaagctg cattcatagc gctacatttt gttaatgcta
     3721 atttagaaaa taattttcaa gagtcgtata aaatcactga aataattatg ggaattgaga
     3781 aaatcattca agatttctat tgtactgagt ttaaccaaga ttctattgat tattatagat
     3841 tcataactca tataaaatta tttgcccatc gcttggttga aaatacaact tattgtgacg
     3901 atgatgatga agacttgtta gcattaatga aaaataaata tcctagagaa tatgaatgtg
     3961 gtgaacaggt ggcaatgttt atacaaactg agtacaatta tttgctgact tctagtgaat
     4021 tagtttattt gatggctcat attcgtcgct taacaaaaaa tttagattaa tagaatagga
     4081 gaataccatg agttataaag ataaggtaca aaaaatcttc gatgtaattg gaggtgaaaa
     4141 aaatgtcaat agagttaccc attgtgtaac acgtttaaga ttagaattaa aagatgaaaa
     4201 tttagtcaat gatgatgatg tgaagaagat accaggtgta ataggtatta tgaaaaagaa
     4261 tggacaatat caaattatac ttggtaatga tgtagctaat tattataaag aattcgttaa
     4321 acttggcaat tttgaatccg attcagttgt tcaagggcac aaagggaata ttttagaaag
     4381 aatcattgag tatatcgctg gttccatgac tccaatcatt ccagcaatgt tagggggagg
     4441 tatgctgaaa gtcttggtaa ttattttacc aatgcttggt atattgcaat cagattctca
     4501 gactattgct tttttgacat tttttgggga tgctccatat tatttcttac cgctgttatt
     4561 agcttattct gcatcacaaa aattaaaagt aacatctaca ttagctatgt ctgtagcagg
     4621 tgtacttctc catccaaatt ttgttcaaat ggtgcaatca gggaatcctc ttagtttatt
     4681 tggtgtacct gtgacaccag ctagttatgg ttcgtcagtc gttccaattc ttattatggt
     4741 ttggttgatg aaatatattg aaaaaatgat tgctaaatta acaccagctg ttactaagag
     4801 ttttttgcaa tctacgctag tattattagt atcaagctgt attgccttag ttgtagtcgg
     4861 acctattgga gtaattgttg gtcaaggatt atcaaatcta gttgggcaaa tgtatggtgt
     4921 agctggatgg cttacattag ctattcttgg tgctattatg ccatttattg ttatgactgg
     4981 aatgcattgg gcttttgcac ctattttttt ggcggcatct attgctactc cagacgtatt
     5041 aattcttcca gcaatgttag ggtcaaactt agctcaaggg gctgcttcga tggctgttgc
     5101 attaaagagt aaaaataata atacaaaaca aattgctttt gcagcaggtt tctcagcctt
     5161 atttgcagga attaccgaac ctgcagtata tggtgtgact ttaaaatata aaaaaccgct
     5221 ttatgcagct atgattggtg gtggattagc gggattattt gcaggtctta ctagtgttaa
     5281 agcgtatcta tttgctgtcc catctttgat agcgttgcct caatttattt attctgatgt
     5341 accatcaaat attgtaaatg ctttaattgt ggcggttatt tcggttgtta ttacctttgt
     5401 attagcttat atatttggaa tcgatgaaga agagagttct agcaatttag aagttaaagc
     5461 tggagtttca aataaaaaaa tgatattttc tcctatatca ggagaaatca ttccgttaag
     5521 cgatgtccag gataaaacat tttcagataa actaattgga gacggggtag cgattatccc
     5581 aagtgaaggt aaggtttatg caccatttga tgggaaaatt acaaatattt ttccgactaa
     5641 gcacgcaatt ggattgaaga gtgatgaggg tgttgagtta ctaattcata ttggattaga
     5701 tactgttgag ctaaaaggtc aaggttttat tagtcatgta gaagaaggag acagagtttt
     5761 caaaaatcag ttgatttttg aaatggactt gaatttaatc aagactaaag gctacgaaac
     5821 agttacacca gtaattgtaa cgaataccaa tgattttcta gatgtattag tattacctaa
     5881 taatcagaca atcgagcatt ctaaggaatt actggtaata ttataatgga ggaaagttat
     5941 gaccattttt ccagatgatt ttctttgggg tggagctgtt gcagctaatc aagtagaggg
     6001 agcatataat gaagatggta agggcttatc agttcaggat gtgttaccca aaggtggatt
     6061 aggagaagca acagaaaatc ctacagaaga taacttaaaa ttgttaggta ttgattttta
     6121 tcataaatat aaggaagata tatccttgtt ttctgaaatg ggctttaatg tttttcgtac
     6181 ttctattgca tggagtagaa tttttccaaa aggagatgaa gaagaaccta acgaagctgg
     6241 tttgaaatat tatgatgaat tgtttgatga actacatgct cacgggatag agccacttgt
     6301 aactctttca cactatgaga ctccattata tttagcaaga aaatatcatg gatgggttga
     6361 taggagaatg attcattttt atgaaaaatt tgctcgaaca gttttagaaa ggtataaaga
     6421 taaagttaaa tattggctta catttaacga agtaaactct gttttggaat taccatttac
     6481 tagtggagga atagatatac ctaaggagaa tctttcgaaa caagaattat atcaagctat
     6541 acatcatgaa ttagtcgcct caagtttggt tacaaaaatt gctcgtgaga ttaattcaga
     6601 gtttaaggtg ggatgtatgg tattagctat gccagcttat ccaatgactc caaatccaaa
     6661 agatgtatgg gcgactcatg agtatgagaa tctaaattat ctattttcag atgtgcatgt
     6721 tagaggttat tatccgaatt atgcaaaaag atattttaag gaaaatgaca ttaacataga
     6781 gtttgcagct gaagatgcag agttattaaa aaattatact gtagattttt tatcctttag
     6841 ctattacatg agtgtgactc aatctgctct tccaacacag tataattcag gagaagggaa
     6901 tattattggt ggtttagtaa atccttattt agagtcttca gagtggggat ggcaaattga
     6961 tccaattgga ctacgtataa ttttaaatag atattatgac cgttatcaaa tcccattatt
     7021 tatagtagaa aatggattag gtgctaaaga tcaactaata aaagatgaac ttaataactt
     7081 aaccgtccaa gatgattata gaattcagta tatgaaagaa catttattgc aagttgctga
     7141 agctctacag gatggtgttg aaattatggg ctatacgtct tggggatgta ttgactgtgt
     7201 ttctatgtcc actgcacaac tttctaaaag gtacggtctc atttatgttg atcgaaatga
     7261 tgatggaaat ggcacattca atcgatataa gaaaatgtcc tttacttggt ataaaggagt
     7321 gattgaatca aatggagaat ccttattcaa atagtttgtt tattgatgat tagatattat
     7381 cacggttaag gcaacatctc attaaatatg aaataaagag gtttggaaga catcaaattc
     7441 taaacctctt tattttatag ggggattaat taatttaatt ttgttacaga gagccgatta
     7501 taaatagtta acttaggata gattggttat atatagtaga ctgaatctaa aatagtacga
     7561 aacaattgct aaaacattta tagaaattaa ttttactttc ccaatcgatt tgttttcatc
     7621 ttatttcaat ccgctataaa gttagataag aataagctaa caagcagaag taagataggt
     7681 cttgcaagaa tggtaaaaat ctgataaact aagtagtaat tgaataggaa tctgaaagac
     7741 tagtagccca agggaagtat atcagggagg agagccgtga ctgcaagctc tctatatgaa
     7801 agctgggtga attcacttgc gcatggattt agaaatgaag gtctgacttg tcagatgaaa
     7861 acggatggta ccgcgtgtca acgctccgag tggagttttt ggcatgtggt tttcttttta
     7921 tctacgagag actgatggag gaaatatgtc aactattgaa gaacaattaa aagcgcttcg
     7981 cgaagaaacg ctggctagct tgaagcagat tactgctgga aatgaaaaag agatgcaaga
     8041 tttgcgtgtc tctgtccttg gtaaaaaggg ttcgctcact gaaatcctca aagggatgaa
     8101 agatgtttct gctgagatgc gtccaatcat cgggaaacac gtcaatgaag ctcgtgatgt
     8161 cttgacagct gcttttgaag aaacagctaa gctcttggaa gaaaagaaag tcgcggctca
     8221 actggctagc gagagtatcg atgtgacgct tccaggtcgt ccagttgcga ctggtcaccg
     8281 tcacgttttg acacaaacca gtgaagaaat cgaagatatc ttcatcggta tgggttatca
     8341 agtcgtggat ggttttgaag tggagcaaga ctactataac tttgaacgta tgaaccttcc
     8401 aaaagaccac ccagctcgtg atatgcagga tactttctat atcactgaag aaatcttgct
     8461 ccgtacccac acgtctccag ttcaggcgcg tgctatggat gcccatgatt tttctaaagg
     8521 tcctttgaag atgatctcgc cagggcgtgt cttccgtcgc gatacggacg atgcgaccca
     8581 cagtcaccaa ttccaccaaa tcgaaggctt ggtagttggg aaaaatatct ctatggctga
     8641 tcttcaagga acgcttcagt tgattgtcca aaaaatgttt ggtgaagagc gtcaaattcg
     8701 tttgcgtcca tcttactttc cattcacaga gccatctgtt gaggtggatg tttcttgctt
     8761 caaatgtggt ggagaaggct gtaacgtatg taagaaaaca ggttggatcg aaattatggg
     8821 ggccggtatg gttcacccac gtgtccttga aatgagtggt atcgatgcga ctgtatactc
     8881 tggctttgcc tttggtcttg gacaagagcg tgtagctatg ctccgttatg gaatcaacga
     8941 tatccgtgga ttctaccaag gagatgtccg cttctcagaa cagtttaaat aatgattaga
     9001 aaagtagaaa tggcagatgt tgaggtgttg gctaaaattg ccaaacaaac ctttcgtgaa
     9061 acctttgcgt atgataatac ggaagagcag ttacaggaat actttgaaga ggcttatagt
     9121 ctgaaaactt tgtcaactga gttgggaaat cctgactctg aaacctattt cattatgcat
     9181 gaggaggaga tagctggttt tctcaaagtc aactggggaa gtgctcaaac tgagagagaa
     9241 ttagaggacg cttttgaaat tcaacgcctc tatgtgctac aaaaattcca aggatttgga
     9301 ctaggtaagc aactgtttga atttgctctt gaacttgcta caaaaaatag tttttcttgg
     9361 gcttggttag gtgtttggga gcataataca aaagctcaag cgttttataa ccgatatggt
     9421 tttgaaaaat ttagccaaca tcattttatg gttggtcaaa aagtagatac ggattggtta
     9481 ctgagaaaga aattaaggta agaagatgat tcttctattg aaatgatagg aaaggaaaag
     9541 aactagagtg acaactgtca ttctggagaa ctaaattatg cttgtatctt ataaatggtt
     9601 aaaagaattg gtggacattg atgtgccatc acaggagttg gctgaaaaaa tgtcaaccac
     9661 agggatcgag gtcgaaggtg tcgaatcacc agctgccggt ctttcaaaaa ttgtcgtcgg
     9721 tgaggtcttg tcttgcgaag atgtgccaga aactcacctc catgtttgtc aggttaacat
     9781 tggcgaagaa gaagctcgtc aaatcgtttg tggtgcccca aatgtgcgtg caggcatcaa
     9841 ggttatggtg gctcttccgg gagctcgtat cgctgacaat tacaaaatca aaaaaggaaa
     9901 aatccgtggc ttagagtcac ttggaatgat ctgttcactt ggtgaattgg gtatttctga
     9961 ctcagttgta cctaaggaat tcgcagatgg tattcaaatt ttgccagaaa atgccgttcc
    10021 aggtgaggaa gtcttctcat atctagactt ggatgatgaa atcatcgaac tttctatcac
    10081 accaaaccgt gcagatgccc tttctatgtg tggggttgcg cacgaagtag cagccatcta
    10141 tgacaaggca gtcaacttta aagaatttac tttgacagaa acaaatgaag ctgcgacaga
    10201 tgccctttct gtgggcattg agacagacaa ggcaccttac tatgcggccc gtatcttgga
    10261 caatgtgacc atcgcaccaa gtccacaatg gttgcaaaac cttctcatga acgaaggcat
    10321 ccgtcccatc aataacgttg tagacgtgac aaactacatc cttctctact ttggtcaacc
    10381 tatgcatgcc tttgacttgg atacctttga agggactgac atccgtgtgc gtgaagcgcg
    10441 tgctggtgaa aaattggtga ccttggacgg tgaagaacgt gacttggacg tgaatgacct
    10501 agtcatcact gtcgcagaca agccagtagc ccttgcaggt gtcatgggtg gtcaagcaac
    10561 agaaatctct gaaaaatcta gtcgtgttgt ccttgaagct gctgttttca atggcaaatc
    10621 tatccgtaag acaagtggtc gcctgaacct tcgttctgag tcatcttctc gctttgaaaa
    10681 aggaattaat gtggcaacag ttaatgaagc ccttgatgcg gcagctagca tgattgcaga
    10741 gcttgcaggc gcgacggtgc gtaagggtat cgtttcagcg ggtgagcttg atacttcaga
    10801 tgtagaagtt tcttcaaccc ttgttgatgt taaccgtgtc ctcggaactg agctgtctta
    10861 tgctgatgta gaagacgtct tccgtcgtct tggctttggt ctttctggaa atgcagacag
    10921 ctttacagtc agcgtaccac gtcgtcgttg ggatatcacg atcgaagctg acctctttga
    10981 agaaatcgct cgtatctatg gttatgactg cttgccaact agtctaccaa aagacgatgg
    11041 tacagcaggt gaattgacag ccacacaaaa actccgccgt caagttcgta ctattgctga
    11101 aggggcaggc ttgacagaaa tcatcaccta tactctaaca actcctgaaa aagcagttga
    11161 gtttacggct caaccaagta accttacgga actcatgtgg ccaatgacag tggaccgttc
    11221 tgtcctccgt caaaatatga tttctggtat cctagatacc gttgcttaca acgtggctcg
    11281 taagaacaaa aacttggccc tttacgagat tggaaaagta tttgaacaaa caggtaatcc
    11341 aaaagaagaa cttccaaatg agatcaacag ctttgccttt gccttgacag gcttggttgc
    11401 tgaaaaagat ttccaaacag cagcagttcc agttgatttc ttctatgcta aaggaatcct
    11461 agaagcgctc tttactcgct tgggactaga agtgacctat acagcaacag ctgagattgc
    11521 cagccttcac ccaggacgta cagcagtcat ttcactcggt gaccaagttc ttggttttct
    11581 tggccaagtg catccagtca ctgctaaggc ctacgatatt ccagaaacgt atgtggctga
    11641 gcttaacctt tcagctatcg aagctgcgct tcagccagcg actccatttg tagaaatcac
    11701 caaattcccg gcagtcagcc gtgacgttgc ccttctcctc aaggcagaag taactcatca
    11761 agaagttgta gatgctatcc aagctgccgg cgtgaaacgt ttgacagata tcaaactctt
    11821 tgacgtcttc tcaggtgaga aattgggact tggtatgaag tccatggctt atagcttgac
    11881 cttccaaaat ccagaagata gcttaacgga cgaagaagtc gcacgctata tggaaaaaat
    11941 ccaagcatcg ctcgaagaaa aagtcaatgc agaagtgcgt taaacgatag tatgatacaa
    12001 attccccctc tagtttatga acactagagg ggtgatttta tataaaataa ttaaaatgtg
    12061 atttctgtaa aaatacatct atgatcagag ttttgaaaac ttacaatgtc taaatctcta
    12121 acatagtagt ggtttttagg caataagata tgatctatcg ttgcattaaa aagttttgga
    12181 ctttggctat tccaagttcc tctttcaaaa ggtggaagtg cattcaatgc gtccctatga
    12241 gagcttattt ttgcaagtgc tccatgacgc atagttgcat taaaatcacc tgcaataata
    12301 gcctttggat attttgaagc caattgatta tgaatgatgt ttaagtcttg cttccagatt
    12361 tccattaaac ctggcagagg aggagcagta tgcaaggcaa tgatatctgg tatattttgt
    12421 tttctcgaat gtaatacaat tgtcccgaac cgtgttgtat gaaaagtttt agcttctgta
    12481 tagaaaccat aacttttctt gacaatcaca gtcacaggag ctattccatt attggtaggt
    12541 ggagaagtga aaatatcata gttggccata gaaagtccaa cttgatgaaa caatagtttg
    12601 attctctggt tttcttgctc acctctgata ttggtagcta gttcagggaa tatagccata
    12661 tcggcatcaa aatggctaaa aattcgctca atatgttgtg cttctatttg attagcgacg
    12721 ttccaagtta ctaattttaa ggttttagtc ttatttgatg cagaagaaag ggttttatct
    12781 gttccaaata atagtaatat gagcgatagt aagagcaaaa tgccagagta aaaccgtatt
    12841 tgtttatttt tcttgtaaaa agataggaaa aaaaaataag aaacttaaaa tagcagccat
    12901 agttgcagta gctaagggga aggcataaat ctgtgccaag ataggttggg tagatagcca
    12961 aatgttaaga ttagaagatg ggaaaaaaga ataagctatg atagggataa caaagagaat
    13021 gaccgaaagg gcagagagaa atgttttaat cattgtgtga gtacctcaat ttgcaatggt
    13081 tgctcggagc taatgtgact ttgtgacttt acttgatgat attcttttta ttgtcttcct
    13141 tatagattaa gtacaaccca agtaaaaaaa gttcaattta agattgaaat gattaaaagg
    13201 cacagaaatg caagacaatt atactacaaa aggcaaacat ttgacaatcg atagccgtcg
    13261 cttaatcgaa cgatggaaaa aagaaggaaa atcaaataga gaaattgcct ctctacttgg
    13321 aaaagctcct caaactatcc acactgaaat caagcgtggg acagtccgac aatgtcttgg
    13381 aaaagggcgt ttcaaagaga tttattctgc cgactatgct caacagtctt atgaaaacaa
    13441 tcgcaagcgc tcggtcaaga aatcaagctt gaccaaggaa ctaaaggaaa agcttctcca
    13501 ctatcataac caaaaatttt cgcctgaaat gatggtgatg gctaaagggg ttaacgtggg
    13561 aatttcaatc atttactatt ggattcatca tggaaaattg ggattaagca aacaggatct
    13621 gctttaccct agaaaaggaa aagcgcttaa gaaacaagct agtcccaact ttaaatccgc
    13681 tggtcaatct atcaaatcat aattcgctca ttttttcaaa aatacataga cgtaaaagaa
    13741 agagggttaa gtgatgaaga atagtgctat tgggagtaat tggaaggatg tccatctgag
    13801 ttctttagca aggaggaaat ccttgaaagt gatatgcgag tggctattat gagcgagttg
    13861 attgaggcta ggcatgaaca aggaatcagt caaaaaaagc tggaagaatt cagtggagta
    13921 agccagcctg tcatagctag gatggaaaca ggcaagacta gccctcagtt ggatacagtc
    13981 ttaaaagtct tatccagttt gggaaagaca ctagtagtag tctcactcga acagagaaag
    14041 agttgattag agtagactta tactcaatga aaatcagaga gcaaactagg aaactagccg
    14101 ctgactgtac ttgagtacgg caaggcgacg ttgacgcggt ttgaatttga ttttcgaaga
    14161 gtattatagt cttttctaat aacaagccat agtcacttat aagaattact aataacatgt
    14221 tttagtattc taattggaat atagctgtaa agtaagaatt acaaaggatt tgagacgttt
    14281 gcttcaagtc tttttctttt gtccgaaaca gagatatagt ttcaaactat atcaaaccct
    14341 aattttttac aattatacag acgctttctt ttctgttaag atagtttcaa caacaaattt
    14401 tggaggacac atcatgtcaa ctacaatcat cggtttccct cgtttggggg aattccgtga
    14461 attaaaattt acaactgaaa aatactttag aaaagaaatc ttagaggaag aacttttagc
    14521 agcagcaaaa gacttgcgtg ctaaacactg gaacattgtc aaagaaaaag gtatcactga
    14581 gattccatca aatgactttt ctcactatga taacttccta gatgcagctt tccttttcaa
    14641 cgtagtacct gcatccgttc aaaacttgaa cttgtctgac cttgagcgct acttcgcttt
    14701 gggacgtggt taccaaggag aaaaagggga cgttcgcgcc ctcccaatga agaaatggtt
    14761 taacactaac taccactaca tcgttcctaa atttgaaaaa gacactcaag tcaaacttgc
    14821 aggtcacaag atttttgatg agttccaaga agccaaagaa cttggattga acactcgtcc
    14881 tgttcttgta ggtcccttca ctttccttca attgtcagac tttgaagaag gcgtgaaagc
    14941 agacgacttc gtagatagct tagtggctac ttaccaagaa gtttttgcta aattggctga
    15001 acttggtgcg actcgcatcc aattggatga agcggctctt gtaaaagact tgacagctga
    15061 agaaaaagct ctcttcttga acctttacaa caaactcttg gctgacaaaa aaggtcttga
    15121 agtcttgctt caaacttatt tcggtgatgt tcgtgacgta tacgctgacc ttgtaaactt
    15181 gccagtagat gctatcggtc ttgactttgt tgaaggtaag aaaactcttg aactcgttaa
    15241 aggtggcttc ccagctgaca agactctcta tgcaggtatt gtcaatggta aaaacatctg
    15301 gcgtaacaac tacgaaaaga gcttggctgt tcttgagcaa atcccagctg aaaacatcgt
    15361 tttgacaagc tcttgctcac ttcttcatgt gccatttaca actgctaatg aagaatttga
    15421 accagcactc ttgaaccact ttgcctttgc agttgaaaaa ttggatgaaa tccgtgactt
    15481 ggatgctatc cgcaatggtc aaggttcaga agctcttgca gccaacaaag aactctttgc
    15541 gactgagcgt gttggtgaaa atgctgaact tcgtgcgcgt atcgctggct tgacagacgc
    15601 agactacact cgtttgccag cctttgcaga acgtgaagct atccaagaag aagctttcaa
    15661 acttccagct cttccaacaa caacgattgg ttcattccct caaacaaaag aagttcgtgc
    15721 caaacgtttg gcttaccgta aaggtgaatt gtctcaaaaa gagtacgatg ctttccttgc
    15781 tgaaacgatt gacgaatgga tcaagtggca agaagatatt gactttgatg tccttgttca
    15841 cggtgaattt gagcgtaatg acatggttga gtacttcggt caaaacttgt caggatacct
    15901 cttctctaaa aatggatggg tacaatcata cggtatgcgt ggggtaaaac caccaatcat
    15961 ctggggtgat gtcactcgtc ttaaccctat cactgttaaa tggtctagct atgcacaaag
    16021 tcgtacaaac aaacctgtta aaggtatgtt gactggacct gttaccatcc ttaactggtc
    16081 attcccacgt gaagacatct ctatcaagga ttcaactctc caaatcgccc ttgctatcaa
    16141 ggatgaagta cttgaccttg aagctgctgg tgtgaaaatc atccaaatcg acgaggctgc
    16201 tcttcgtgaa aaattgccac tccgccgtag cgactggtac gaagactacc ttgactgggc
    16261 tattcctgcc ttccgcttgg tacactcaac agtagcgcca gacacacaaa tccacactca
    16321 catgtgttac tcagaattta cagatatcat cccagctatc gataacatgg atgcagacgt
    16381 tatttccttt gaagctagcc gttcaaacct tgaaatcttg gacgaactca aagcgaaaaa
    16441 cttccaaaca gaagtgggac ctggggttta cgatatccac tcacctcgtg taccaaatga
    16501 aggcgaaatc gacaacacaa tcgaagccat ccttgctaaa gtgccaagca agaaagtttg
    16561 gatcaaccct gactgtggtt tgaaaacacg tggtatccca gaaacaaaag aaagcttgat
    16621 ccgccttgtt gaagcagcta aagctgcgcg tgagaaattg taagattgga tttctctcca
    16681 tacagtggtt gttcaaaaag aaatcaacta gaaaaggtta ttacatatgt cacgccaaac
    16741 accgtcactc tcatttgaag tgttccctcc aaacccagcc gtgggtaatg ataacattat
    16801 ttcagccttg caggatatgc aggaattggc tccctatttt atcagtgtaa ctgccagcaa
    16861 taataaattt aatatcaagg aaacgacggt tcgtttggct gactttatcc aaaatgattt
    16921 ggcgattccg accattgccc acttgccagc tatttatcta actaaggaca aggttgctga
    16981 aactattgct gacttggaca aagttggggt gcagaaaatc ttggctcttc gtggggatat
    17041 tattccagac gtggaaccac aaaaggattt ccgctatgca accgacttga ttgagtttat
    17101 caaggaacaa acccctcact ttgatattat tggagcttgc tatccagaag ggcatccaga
    17161 ttcgccaaat cagatttcag atattcaaaa tcttaagaag aaagtggatg caggctgttc
    17221 gagcctcgta actcagctct tctttgacaa tgagcgcttc tatgattttc aggacaagtg
    17281 tatcttggct gggattgatg ttcccattca tgcaggaatt atgccaattc tgaatcgaaa
    17341 tcaggctctc cgactcttga agacttgtga gaatatccat cttccacgca aatttaaagc
    17401 catcttagac aagtatgagc atgaccctga gtcgctcaga gcagcaggac ttgcctatgc
    17461 agtggaccaa atcgtggact tggtaactca ggatgttgcc ggtgtgcatc tctatacgat
    17521 gaataatgct gatacagcaa aatacatcca tcaagcaacc catgccttgt ttaatcacca
    17581 gtctctagga taataaaagc aaaccattct tctcaggtga ggggaatggt tcctttttaa
    17641 tggtaaagac ctcacttttt aagaaaaata tgataaaata aattctgtac gtacttgata
    17701 caaagatgaa ggtattaaat aatacaatgc atttaaactg taagatttaa cgacacgagt
    17761 gagtcaaatc gatgttattt gacgagagag ttagtaaagc atttagctaa tcgcccgata
    17821 gcgattagcg tgaaagcttt agatatttta gtattaaacc tttctaatga tgtatcttga
    17881 aaactgaact tgcctacaac tctgtggaaa aagataaatc tccctaggag cagtcgctcc
    17941 gtcgttcgat ttcctat
//
LOCUS       DAVDZK010000043        15843 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVDZK010000043 DAVDZK010000000
VERSION     DAVDZK010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15843
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.044"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            414..6854
                     /locus_tag="VUX16_001791"
     CDS             414..6854
                     /locus_tag="VUX16_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET8124700.1"
                     /translation="MKKSTVLSLTTAAVILATYAPNEVVLADTSNSEDALNISDKEEV
                     VVDKETENKEKKTAVIEGKEVVSKNPVTDNNTSNEEATIKEDSNQSQGDHADSFVNKN
                     TENPKKEDRLVYIAEFKDEESREEAIKRLSNLKNTKVLYTYDRIFNGSAIETTPDNLD
                     KIKQIEAISSVERAQKVQPMMNHARREIGVEEAIDYLKSINAPFGKNFDGRGMVISNI
                     DTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFNYYNGGKITVEKY
                     DDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYKMYSDAGSGFAGD
                     ETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGIPMVVATGNYATS
                     ASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDKVNIGGQSFKYRN
                     IGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLKGKIAVMDRIYTKDLKN
                     AFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVFSISGDDGVKLWN
                     MINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEIDFKFAPDTDKEL
                     YKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTYGYMSGTSMATPI
                     VAASTVLIRPKLKEMLERPVLKNLEGDDKIDLTSLTKIALQNTARPMMDATSWKEKSQ
                     YFASPRQQGAGLINVANALRNEVVATFKNKDSKGLVNSYGSISLKEIKGEEKYFTIKL
                     HNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVPEIHPEKIKGANIT
                     FEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEALNSNGKKTNFQP
                     SLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGKPKIPGTLNKGIGGEHGI
                     DKFNPAAVIQNRKDKNITSLDQDPDLFAFNNQGIHAESTSGSNVANIYPLDSNGNPQD
                     AQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHFIRGILNSKSNDAK
                     GIKSSKLKVWGDLKWDGLIYNPRGREENEPESKDNQDPATRIRGQFESIAEGQYFYKF
                     KYRLTKDYPWQVSYIPVKIDNTAPKIISIDFSNPDKIKLIAKDTYHKVKDEYKHETLF
                     ARDQKEHPEKFEEVANEVWYAGAALVDEYGDVEKNLDVTYAGEGEGRNRKLDKDGNTI
                     YEISGAGDLRGKIIEVIALDGASNFTKIHRIKFDDQADEKGMISYYLVDPDKDASKYE
                     KLGEISEEKLKNAKSPEENTNNNQAKDEDSKPDEESSVEGEASLEINKTISTIRDFEN
                     KDLKKLIKKKYREEYDFVTGGKRTVELDYQYDDKGNITAYEDESALEYETEKLDDVKS
                     KLGGVLSPSKDGHFEILGKVSNVSKNAKAYYGNDFKLIEIKASKYDPQTKTLTFDLFA
                     NTNDVVDGLSFTGDMNILVKDKGETKAKTKIRMPEKNKETKTEYPYASSYGNVIELGE
                     GDLSKNKPNNLTEMESGKIYSDSEKQQYLLKDNIILRKGYALKVTTYNPGKTDMLAGN
                     GVYSKEDIAKIQKTNPNLRVLSETTIYADSRNVKDGRSTQSVLMSALDGFNIVRYQVF
                     TFNMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYHGEEYSNVEAIKEDGSMLFIDTKP
                     VNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNESVVDNYLIYGDLH
                     IDNTRDFNVKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQTGYSDLNAKAVGV
                     HYQFLYDNVKPEVNIDPEGNTSIEYADGKSVVFNINDKRDNGFNGEIQEQHIYVNGKE
                     YKSFDDIKQLTDKTLNIKILVKDFARNTTVKEFILNKDTGEVRELKPHTVTVTMQNGK
                     EMSSKIVSEEDFILPVYKGELEKGYQFDGWEIAGFEGKKDAGYVINLSKDTFIKPVFK
                     KIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHSQKSDSTKDVNATV
                     PGRNDKNFENKTEVYPNEPENIANKDTNIDSKLTTNNLNKSPKTGTVSGVFTSLVAGI
                     MFTVGAFLGLKKKD"
     gene            7338..7646
                     /locus_tag="VUX16_001792"
     CDS             7338..7646
                     /locus_tag="VUX16_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124701.1"
                     /translation="MKKLLGIVFLVAAATVVYFGSVGWPSLDVNLWSLIPVGLFLFFT
                     LENLLKKDYKASLMCLIIAFIIANAILDLLPISSGLVIGAGVLACVGIGYLFPDKEGK
                     "
     gene            complement(7877..8236)
                     /locus_tag="VUX16_001793"
     CDS             complement(7877..8236)
                     /locus_tag="VUX16_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET8124702.1"
                     /translation="MDMILMKLASILLLILTLVVCIIITKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSVLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLVMYIEMIVELMAQK"
     gene            8328..9257
                     /locus_tag="VUX16_001794"
                     /pseudo
     CDS             8328..9257
                     /locus_tag="VUX16_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003023668.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9260..9817
                     /locus_tag="VUX16_001795"
     CDS             9260..9817
                     /locus_tag="VUX16_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET8124703.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVAKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDIERDAVLDFVSQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            9810..10064
                     /locus_tag="VUX16_001796"
     CDS             9810..10064
                     /locus_tag="VUX16_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124704.1"
                     /translation="MDKQYLREKLDAMRQNFVESTHHERAVGVLDQVHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFEFCCKKD"
     gene            10076..12130
                     /locus_tag="VUX16_001797"
     CDS             10076..12130
                     /locus_tag="VUX16_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET8124705.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVKAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLTLIALTFVLFAIRFVMIYGYF
                     ACRTRRLKKKLNKYMKDMLLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLSSRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDIVELVR
                     RN"
     gene            12297..13157
                     /locus_tag="VUX16_001798"
     CDS             12297..13157
                     /locus_tag="VUX16_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET8124706.1"
                     /translation="MKKWWKELTDKPLVKSFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFVKDILPESLYEGVEKISREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMVSLLVSFGLQLLFAFALFLSLFGQMIL
                     DLLAHYWTKDGIIYQSLQGLAGPLIYVLLFAILVMLYYFLPNLSNRKLSYTLPGSAFV
                     LLVILGLLTLFSSYLNYYIHRLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13368..14078
                     /gene="ccdA2"
                     /locus_tag="VUX16_001799"
     CDS             13368..14078
                     /gene="ccdA2"
                     /locus_tag="VUX16_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET8124707.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14098..14664
                     /locus_tag="VUX16_001800"
     CDS             14098..14664
                     /locus_tag="VUX16_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET8124708.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSMTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKDAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTQPGFMEKDAILQTLKELA"
     gene            14675..15787
                     /gene="msrB"
                     /locus_tag="VUX16_001801"
     CDS             14675..15787
                     /gene="msrB"
                     /locus_tag="VUX16_001801"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET8124709.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVN"
BASE COUNT         5275 a         2598 c         3311 g         4659 t
ORIGIN      
        1 ggtgggtttt tttgtgtttt aaggagacta ttaagccaga attttggact tatactcttc
       61 gaaaatctct tcaaattatg tcaggttgta tggttactga cttcgtcagt cttatctgga
      121 acctcaaaac agtgctttga gtaacctacg gttagcttcc tagtttgctc tttgattttt
      181 attgagtact aatcttattt tttaatgtgt gttaaaaaat aaattaagac atattaattt
      241 ttcttgactt aaatttttta aatgatatac tattcttatg gagagctaac aattatatat
      301 aaatgtacta ctctatttcc tagataatac ttagtaaaac tttttataac aaaggctagc
      361 aaagttaaag tttattatct attggaagtt aaataaatat gtaaggaatt aaaatgaaaa
      421 aaagtacagt attgtcatta accacagctg cagttatttt agcaacctat gcccctaatg
      481 aggtagtctt agcagacaca tctaactctg aagatgcttt aaatatctct gataaagaag
      541 aagtagtagt agataaggaa acagaaaata aagagaagaa aacagcagtc attgagggaa
      601 aagaagttgt tagtaaaaat cctgtgacag acaataacac tagcaatgaa gaagcaacaa
      661 tcaaagaaga ttccaatcaa tcccaaggag atcatgcgga ctcatttgtg aataaaaaca
      721 cagaaaatcc aaaaaaagaa gatagacttg tctatattgc tgaatttaaa gatgaagagt
      781 ctagagaaga agcaatcaag agactatcaa atcttaagaa tacaaaagtt ttatatactt
      841 atgatagaat ttttaacggt agtgccatag aaacaactcc agataatttg gacaaaatta
      901 aacaaataga agctatttca tcggttgaaa gggcacaaaa agtccaaccc atgatgaatc
      961 atgccagaag ggaaattgga gttgaggaag ctattgatta cctaaagtct atcaatgctc
     1021 catttgggaa aaattttgat ggtagaggta tggtcatttc aaatatcgat actggaacag
     1081 attatagaca taaggctatg agaatcgatg atgatgccaa agcttcaatg agatttaaaa
     1141 aagaagactt aaaaggaact gataaaaatt attggttgag tgataaaatc cctcatgcgt
     1201 tcaattatta taatggtggc aaaatcactg tagaaaaata tgatgatgga agggattatt
     1261 ttgacccaca tgggatgcat attgcaggga ttcttgctgg aaatgatact gaacaagata
     1321 tcaaaaactt taacggcata gatggaattg cgcctaatgc acaaattttc tcttataaaa
     1381 tgtattctga cgcaggatct gggtttgcgg gtgatgaaac aatgtttcat gctattgaag
     1441 attctatcaa acacaacgtt gatgttgttt cggtatcatc tggttttaca ggaacaggtc
     1501 ttgtaggtga gaaatattgg caagctatta gggcattaag aaaagcaggc attccaatgg
     1561 ttgtcgctac gggtaactat gcgacttctg cttcaagttc ttcatgggat ttagtagcaa
     1621 ataatcatct gaaaatgacc gacactggaa atgtaacacg aactgcagca catgaagatg
     1681 cgatagcggt cgcttctgct aaaaatcaaa cagttgagtt tgataaggtt aacattggag
     1741 gacaaagttt taaatacaga aatatagggg cctttttcga taagaataaa atcacaacaa
     1801 atgaagatgg aacaaaagct cctagtaaat taaaatttgt atatataggc aaggggcaag
     1861 accaagattt gataggtttg gatcttaagg gcaaaattgc agtaatggat agaatttata
     1921 caaaggattt aaaaaatgct tttaaaaaag ctatggataa gggtgcacgc gccattatgg
     1981 ttgtaaatac tgtaaattac tacaatagag ataattggac agagcttcca gctatgggat
     2041 atgaagcgga tgaaggtact aaaagtcaag tgttttcaat ttcaggagat gatggtgtaa
     2101 agctatggaa catgattaat cctgataaaa aaactgaggt taaaaggaat aataaagaag
     2161 attttaaaga taaattggag caatactatc caattgatat ggaaagtttt aattccaaca
     2221 aaccgaatgt aggtgacgaa aaagagattg actttaagtt tgcacctgac acagacaaag
     2281 aactctataa agaagatatc atcgttccag caggatccac atcttggggg ccaagaatag
     2341 atttactttt aaaacccgat gtttcagcac ctggtaaaaa cattaaatct actctcaatg
     2401 tcattaatgg gaaatcaact tatggctata tgtcaggaac tagtatggca actccaatcg
     2461 tagcagcttc tactgttttg attagaccga agttaaagga aatgcttgaa agacctgtat
     2521 tgaaaaatct tgagggagat gacaaaatag atcttacaag tcttacaaaa attgctttac
     2581 aaaatactgc gcgaccgatg atggacgcaa cgtcttggaa agaaaaaagc caatactttg
     2641 catcacctag acaacaggga gcagggctaa ttaatgttgc caatgctttg agaaatgaag
     2701 ttgtagcgac tttcaaaaac aaggattcta aaggtttggt aaactcttat ggttctattt
     2761 ctcttaaaga aataaaagga gaagaaaaat attttacaat taagcttcac aatacatcaa
     2821 acagaccttt gacatttaaa gtttcagcat cagcgataac tacagattct ctaactgata
     2881 gactaaaact ggatgaaaca tacaaagatg aaaaatctcc agatggtaag caaattgttc
     2941 cagaaatcca tccagaaaaa atcaaaggag caaatatcac atttgagcat gatactttca
     3001 ctataggcgc aaattctagc tttgatttaa atgcggttat aaacgttgga gaggctaaaa
     3061 ataaaaataa atttgtagaa tcatttattc attttgagtc agtggaagaa atggaagctc
     3121 taaactccaa tgggaagaaa acaaattttc aaccttcttt gtcgatgcct ctaatgggat
     3181 ttgctgggaa ttggaaccac gaaccaatcc ttgataaatg ggcctgggaa gagggttcaa
     3241 aatcaaaaac aatggaaggt tatgatgatg atggtaaacc aaaaattcca ggaaccttaa
     3301 ataagggaat tggtggagaa catggtatag ataaatttaa tccagcagct gttattcaaa
     3361 acagaaaaga taaaaatatt acatcactag accaagaccc agacctattt gcctttaaca
     3421 accaaggtat tcatgcagaa tccactagtg gatctaatgt tgctaacatt tatcctttag
     3481 attcaaatgg aaatcctcaa gatgctcaac ttgaaagagg attaacccct tctccacttg
     3541 tattaagaag tgcagaagaa ggattgattt caatagtaaa tacaaataaa gagggagaaa
     3601 atcaaagaga cttaaaagtc atttcgagag aacactttat tagaggaatt ttaaattcta
     3661 aaagcaatga tgcaaaggga atcaaatcat ctaaactaaa agtttgggga gatttgaagt
     3721 gggatggact catctataac cctagaggta gagaagaaaa tgaaccagaa agtaaggata
     3781 accaagatcc agctactagg ataagaggac aatttgaatc aatagctgag ggtcaatact
     3841 tctacaaatt caaatataga ttaaccaagg attatccatg gcaagtttct tatataccag
     3901 taaaaattga taatacagct ccaaaaatta tttcaattga tttttctaat ccagataaaa
     3961 ttaaattgat cgcaaaagat acctaccaca aggtaaagga tgagtacaaa cacgaaacct
     4021 tgtttgctag agaccaaaaa gaacatcctg agaaatttga agaagtagcc aacgaagtat
     4081 ggtatgcagg tgcagctctt gtcgatgagt atggagatgt tgagaaaaat cttgatgtaa
     4141 cttacgccgg agagggtgag ggaagaaata ggaagcttga taaagatgga aatactatct
     4201 acgaaattag cggagcagga gatttaagag gaaaaatcat cgaagtaatc gccctagatg
     4261 gtgcaagcaa cttcaccaaa atccatagaa ttaaatttga tgaccaagct gatgaaaaag
     4321 gaatgatttc ttattaccta gtagatcctg ataaagatgc ttctaaatat gaaaaactag
     4381 gtgaaatttc tgaagaaaaa ctcaaaaatg caaagagccc agaggaaaat accaataata
     4441 atcaagctaa ggatgaagat tcaaaaccag atgaagaaag ttcagttgag ggagaagcta
     4501 gccttgaaat aaataaaact atttcaacaa ttagagactt tgaaaataaa gacctaaaga
     4561 aactcattaa aaagaaatat agggaagaat atgactttgt aactggtgga aaaagaacag
     4621 tagaacttga ttatcaatat gacgataaag gaaatataac tgcctatgaa gatgagagtg
     4681 ctctagaata tgaaactgag aaacttgatg atgttaaatc aaagcttggt ggagtattaa
     4741 gcccatcaaa ggatggacat tttgaaattc ttggaaaagt aagtaatgta tccaaaaatg
     4801 ctaaggctta ctatggcaat gacttcaaat taatagaaat taaggcaagt aaatacgacc
     4861 cacaaactaa aactctaacc tttgacttat ttgcaaacac aaatgatgta gtcgatggtc
     4921 tatcctttac gggtgatatg aatatccttg taaaagataa gggtgaaaca aaagctaaaa
     4981 ctaaaattag aatgcctgaa aaaaataagg aaactaaaac agaatatccc tatgcatcaa
     5041 gttatgggaa tgtaatcgaa ttaggagaag gagatctttc aaagaacaaa ccaaacaatt
     5101 taactgaaat ggaatctggt aaaatctatt ctgattcaga aaaacaacaa tatctgttaa
     5161 aggataacat cattctaaga aaaggctatg cactaaaagt gactacctat aatcctggaa
     5221 aaacggatat gttagcaggg aatggagtct atagcaagga agatatagca aaaatacaaa
     5281 agaccaatcc taatctaaga gtcctttcag aaacaacaat ttatgctgat agtagaaatg
     5341 ttaaagatgg aagaagcact caatcagtat taatgtcggc tttggacggc tttaacattg
     5401 taagatatca agtgtttacc tttaacatga atgataaagg ggaagctatc gataaagatg
     5461 gaaatcttgt gacagattcc tctaaacttg tattatttgg taaagatgat aaagagtatc
     5521 atggggagga atattctaat gtagaagcta taaaagaaga tggctccatg ttatttattg
     5581 ataccaaacc agtaaacctt tcaatggata agaactactt taatccatct aaatctaata
     5641 aaatttatgt acgaaatcca gaattttatt taagaggtaa gatttctgat aagggtggtt
     5701 ttaactggga attgagagtt aatgaatcgg ttgtagataa ttatttaatc tacggagatt
     5761 tacacattga taacactaga gattttaacg ttaagcttaa tgttaaagac ggtgacatca
     5821 tggactgggg gatgaaagat tataaagcaa acggatttcc agataaggta acagatatgg
     5881 atggaaatgt ttatcttcaa actggctata gcgatttgaa tgcgaaagcg gttggagtac
     5941 actatcaatt tttatatgat aatgttaaac ctgaagtaaa cattgatcct gagggaaata
     6001 ctagtatcga atatgctgat ggaaaatctg tagtctttaa catcaatgat aaaagagata
     6061 atggattcaa tggtgagatt caagaacaac atatttatgt aaatggaaaa gaatataaat
     6121 catttgatga tattaaacaa ctaacagata agacactaaa tattaagatt cttgtaaaag
     6181 attttgcaag aaatacaacc gtaaaagaat tcattttaaa taaagatacg ggagaggtaa
     6241 gagaattaaa acctcatacg gtaactgtga ccatgcaaaa tggaaaagaa atgagttcta
     6301 agatagtgtc ggaagaagat ttcattttac ctgtctataa gggtgaatta gaaaaaggat
     6361 accaatttga tggttgggaa attgctggtt tcgaaggtaa aaaagatgct ggctatgtta
     6421 ttaatctatc aaaagatacc tttataaaac ctgtattcaa gaaaatagag gagaaaaagg
     6481 aggaagaaaa taaacctact tttgatgtat cgaaaaagaa agataaccca caagtaaacc
     6541 atagtcaatt aaatgaaagt cacagaaaag aggatttaca aagagaagat cattcacaaa
     6601 aatctgattc aactaaggat gtcaatgcta cagttcctgg tagaaatgat aaaaactttg
     6661 aaaataagac tgaagtttat cctaatgaac cagagaacat agccaataaa gataccaata
     6721 tcgatagtaa attaactact aacaatctta ataagtcacc aaaaaccgga acagttagcg
     6781 gagtattcac gtcattggtt gccggaataa tgtttaccgt aggcgcattt cttggattaa
     6841 agaaaaaaga ttaagattaa gacaaaagct atagatgaaa aaatggttta tgtactgaga
     6901 tagtatgatg atgaaacagt tttgtgaaaa tagctattta taactcaatt atttagttta
     6961 ctttactatt gatactcttt ttggatctat taatagactt agtttcgaca actaatgaat
     7021 tgattgaaag ggttagtatt gacaatattg attagaaaat agagtctatc aaaatttaaa
     7081 ggtcaataga ggtgatgaga taatttcaag gaattaagta gtgtttggtt gcttaattcc
     7141 tttttatttg gaaggaagtt tttcacctgc ttccttattt tatcgctatt attcaaccac
     7201 ttagactgag attgagacca gataggcaaa cgaacttgtt cttgaaactg acctctgcta
     7261 taatgatttt tgtaagagac gcaaggcgtc gatattagac aactcaagtt cctaaaaaag
     7321 aaatcggaga taaagaaatg aaaaaattat tggggattgt ctttttagta gcagcagcga
     7381 cagtagtgta ttttggttct gttggctggc caagtttaga tgtcaatctc tggtcactga
     7441 ttccggtagg attgttcctc tttttcactc tagagaatct tttgaaaaaa gactacaagg
     7501 ctagtctgat gtgtttgatt attgccttta tcatcgcaaa tgcaattttg gacctgttgc
     7561 caatttcaag tggcttggtg attggagcag gtgtgctggc ttgtgtaggt attggttacc
     7621 tctttcctga taaagaagga aaataatact cttcgaaaat ctcttcaaac cacgtcagct
     7681 tcgccttgcc gtatatatgt gactgacttc gtcagtctta tctacaacct caaaacagtg
     7741 ttttgagtag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataagaa
     7801 ttattgaaaa agatataaag aaaaacactt caatcactgt atttcagttt gattgaggtg
     7861 ttttagattt agttttttat ttctgggcca tcaattcaac aatcatctcg atatacatga
     7921 ccagggttaa taagaatcct gtacgccaga agaatttgat gaatttagga tagtaaaagc
     7981 tacgtttttt caaaaggaag aaaaaaacga gaataatggc tagaactgag agggctagcc
     8041 ccagtctagg gaggaaatta tgggtaaagg ttttagctgt gatcaggtag tactcaaata
     8101 ccaagactgg aaaggccaaa tccgcaaagt ttcgtcctag tttttttaat ctaaaaagtt
     8161 tggttatgat aatgcagact actagagtca gtatcaataa taaaatagat gctaatttca
     8221 ttaaaatcat atccatattg tatcataaaa aaaggctaat ggaaacgaga aacagaggaa
     8281 tttataggaa agtcaggctt ttgagattgt gggtgatttt tgttataatg agagttatga
     8341 aatcttataa taccttgaat gattattatc gaaaactctt tggagaaaag acctttaaag
     8401 tccctattga tgcgggattt gactgtccca atcgtgatga aactgtggct catggaggct
     8461 gtactttttg tacggtttcc ggttctggag atgccattgt ggcaccagat gcgcctatcc
     8521 gtgagcaatt ttataaggaa attgacttta tgcatcgtaa gtggccaggt gttcagaagt
     8581 atctggttta ttttcaaaat tttacaaaca cccatgaaaa ggtggaagtt attcgagagc
     8641 gttatgaaca ggctatcaat gacccaggtg tggtaggaat caatattgga acgcgcccag
     8701 actgtttacc agacgaaacc atcgaatatt tggctgagtt gtcggagcgc atgcatgtga
     8761 gggttgaatt aggcttgcag actacttatg aagcaacctc tgacctgatt aaccgcgcgc
     8821 attcttatga attgtaggtg gaaacggtca agcgtttgag aaagtatcca aaaattgaga
     8881 ttgtttccca tttgatcaat ggtttacctg gtgaaactca tgagatgatg gttgaaaatg
     8941 tccgccgttg tgtcacggat aacgatattc aagggattaa actgcatttg cttcacctga
     9001 tgaccaatac acgtatgcaa cgagattatc acgaaggacg tttgcagttg atgagccagg
     9061 acaaatatgt taaggtcatc tgtgaccaac tggaaatcat tcccaaacat attgtcatcc
     9121 atcgaattac aggagatgca ccgagagata tgctgattgg ttccatgtgg agcctaaata
     9181 aatgggaagt gctaaatgct attgaaactg aaatgcgacg tcgtggaagt gttcaaggat
     9241 gtaaaacagg agtttgaaaa tgaaaagacc acttgagatg gcacatgatt ttttggctga
     9301 ggtcgtgaca aaagaggatg tcgtagtgga tgcgactatg ggaaatggtc atgacacgct
     9361 ttttttagcc aagctagcca agcaagtcta tgcctttgat attcagaagc aagccttgga
     9421 aaagacccaa gagcgtttgc atcaggctgg cttgacaaat gcccagttaa tcttgcaagg
     9481 ccatgagaca ctggaccagt ttgtggcaaa agctaaggca gggattttta atctgggcta
     9541 tttgccgtca gctgataagt ctgtcatcac ccgaccgcag acaacgattg aggcattaga
     9601 aaagctatgt ggcttacttg tcaaaggtgg acgaattgct atcatgatct actatggtca
     9661 tgaaggaggc gacatcgaga gggatgctgt cttggatttt gttagccagt tgaaccaaca
     9721 agagtacaca gctgccattt accgaacttt aaaccaagtc aacaacccac catttttagt
     9781 aatgattgaa aaattagaga gatacagaca tggataaaca atacctacgt gaaaagctgg
     9841 atgccatgcg ccagaatttt gttgaatcaa cccaccacga acgagcggtg ggcgtgctag
     9901 accaagtgca tatgagcaaa aaaatgctta aaatcaagaa aaaattagtt gctcttgaaa
     9961 tggaacggtg ccagagaaaa attgagcaca aagattgttc caagattgac caaaaaatca
    10021 aagagcagaa ggagatattt gaattctgtt gtaaaaaaga ttaaggagga cgtgcgtgga
    10081 attactgatt tacctcatcc tatttttact ggtcttgatt gtctcaagta caaccaataa
    10141 gctcctaccc tttttgcctc tccctttggt gcagattctt ttgggaattg taattggtct
    10201 ctttttaccc aatactgact ttcaccttaa tacggagttg tttttggcac tggttatcgg
    10261 acccttgctt ttccgagagg ctgaagaagc agatgttaag gctattttaa aacactggcg
    10321 aatcattgtt tatctcatat ttccagtgat ttttatctcg accctgagtt tgggtggctt
    10381 ggcccatctt ctttggttca gccttccctt ggcagcttgc ttggctgttg gggcagccct
    10441 tggtcctacg gacttggtgg cctttgcctc tctttcggag cgttttagct ttcctaagcg
    10501 cgtgtccaat attcttaagg gcgaaggact cttgaatgat gcttctggtt tggtggcttt
    10561 tcaggtagct ttgacagctt ggacaactgg agctttttct ctggggcaag ctagcagttc
    10621 gctcatcttt tcaatcctag gcggtttttt aattggattt ttaacagcca tgaccaaccg
    10681 cttcctccat accttcttgc taagtgtgcg cgcaacggat attgccagtg aacttttact
    10741 agaattgagt ttgcctctag tgaccttctt tctggcagaa gaagtccacg tttcagggat
    10801 tattgccgtc gtagttgctg ggattttaaa ggcaagtcgc ttcaagaaaa tcacgctcct
    10861 cgaagcccaa gtggacacgg tgaccgagac ggtctggcat acagtgacct ttatgctcaa
    10921 cggttctgtc tttgtgattt tagggatgga gctggaaatg atagcagagc ctatcttaac
    10981 caatccaatc tataatccct tacttttatt gctaactctt atagccctta cctttgtcct
    11041 ctttgctatt cgttttgtca tgatttatgg ctattttgcc tgtaggaccc gacgcctcaa
    11101 gaaaaagcta aataagtata tgaaggacat gcttctcttg accttttcag gtgttaaggg
    11161 aacggtgtcg attgctacga ttctcttgat accaagtaat ctagaacagg agtatcctct
    11221 cttgcttttc cttgttgcag gtgtgacgct tgtcagcttt ttaacaggtc tcttggtctt
    11281 gcctcatctt tctgatgaag aggaagaaag caaggattat ctcatgcata tcgccatttt
    11341 gaatgaagta acgctagagt tggaaaaaga gttggaagac accagaaata aacttcccct
    11401 ctatgcggct attgacaatt atcatggacg tattgaaaat ctcattttaa gccaagaaaa
    11461 ccaggatgat caagaagact gggctgcttt gaaactcttg attcttagta ttgaaagtga
    11521 tggtttggaa caggcctatg aagaggggaa cattagcaat cgtgcttacc gagtttacca
    11581 acgttatctg aaaaatatag aacaaggaat caatcgtaaa ctttcctcaa gactaaccta
    11641 ttatttcctt gtttctttgc ggattttacg ttttctcctt catgaagttt ttactctcgg
    11701 aaagaccttc cgtagctgga agaacaagga gcaaagccgt ctccgtgctc ttgattatga
    11761 ccaaattgca gagctctatc ttgccaatac agagatgatt attgaaagtt tggaaaacct
    11821 gaagggagtc tacagacgct ctttgattag ttttatgcag gagtctcgtc ttcgagaaac
    11881 agctattatc agcagtggtg cctttgtcga acgggttatc aatcgtgtca aacccaacaa
    11941 tatcgatgaa atgctgagag gctattatct ggagcgcaag ttgattttcg aatacgaaga
    12001 aaaacgattg attacgacta agtatgccaa gaaattacga caaaatgtaa ataatttaga
    12061 gaactattcc ttgaaggaag ctgccaatac cctgccgtat gatatagtgg aattggtaag
    12121 aagaaattag ttaatactct tcgaaaatct cttcaaacca cgtcagcgtc gccttaccgt
    12181 atgtatgaga gtcttatcta caacctcaaa acagtgtttt gagcagcctg cggctagctt
    12241 ccgagtttgc tctttgattt tcattgagga taagattgta agtgaaggag tgtgacatga
    12301 agaagtggtg gaaagagctg acagacaagc ctttagtaaa atcctttttg cattattatc
    12361 aagcatcaga tagtgagttg accagtgtcg cagtagccta ctattggttg atttcgattt
    12421 ttcccctgct tttggtggtg gtcaatatcc tcccctattt tcagattcct gtgggagaat
    12481 ttctgggatt tgtgaaagac atcctacccg aaagtctcta tgaaggtgta gaaaaaatat
    12541 ccagagaagt cttgacgcaa ccttcaacag gtttattgag cttttctgtc ttatcggcgt
    12601 tatggagctt ttcaaaatct atgaatttcc tgcaaaaagc ttttaacaag gcttatggcg
    12661 tcgaaaagag tcgcggactt atttcccatc agatggtgag tctcttagtg agttttggtt
    12721 tgcaactact atttgctttt gccttgtttt taagcttatt tgggcagatg attttggatt
    12781 tacttgctca ttattggaca aaagatggca ttatctatca gtctttacaa gggttggcag
    12841 gccctctgat ttacgtccta ctctttgcta tcttggtcat gctttattat tttcttccca
    12901 atctatctaa caggaaactg agctataccc taccaggcag tgcctttgtt ctcttagtga
    12961 ttttaggttt actaactttg ttttctagtt atctcaatta ctacatccat cgtttagtgg
    13021 acgtccgaat tttaggttcc gttcttcttg ttgttatgat gttttggttt atcttgattg
    13081 ctaaaattgt tatcctaggc gcggttatca atgccagtat gcagagtttg aaagatccgg
    13141 tctttaaaaa agactaacta tttatccatt acaaaagcgc atagtatcaa gactttatag
    13201 aaccttgata ctatgcgctt ttgtgctttg acagtttttt gtatagtttt tgtccaagat
    13261 ttctaaatca tctgattaaa ttcctatttt cccctatcat tgtccctgtt ttttcgaaaa
    13321 tggaaggagt ataataaatc tatcaataaa atgataggag gaactttatg ggtcatattt
    13381 tcttttttct aagtgtcttt ttggcaggga ttctatcctt cttttctcct tgtatcttac
    13441 ctttgttacc ggtctataca ggggtgttac tagatgataa ggatggtgct caggcttcta
    13501 gcggcaaatt ttcaatctca gttactagtt tattacgaac tctggccttt atagcaggaa
    13561 tttcctttat atttattttg ttgggctatg gagctggttt tttaggcgat ttgctttatg
    13621 cttcttggtt ccaatatctt actggggcaa ttattatcct tcttggtttg caccaaatgg
    13681 agattctaca ctttaagggg ctttataagg aaaagaggct acaactgcaa ggacaggggc
    13741 aaaatggtaa gggctatagt caggcatttt tattgggctt gacctttagt tttgcttgga
    13801 cgccttgcgt ggggccggtt ctggggtctg ttttggcctt ggcggcttca ggtggttcag
    13861 gagcttggca gggagctggt ctcatgttgg tgtatacgct gggcttggcg ctaccattct
    13921 tgcttctagc tctgacctct agttatgttt tgaaacattt ccgaaaactt catccctatc
    13981 tcggaatcct caaaaaagtg ggtggttttc tcattattgt gatgggactc ttggttctgt
    14041 ttggaaatgc ttcaatttta agtcaattat ttgaataaaa tggaaaggaa tatcaatatg
    14101 aaaaaatggc aaacatgtgt tcttggagca ggttcgctcc tttgtttgac ggcttgttca
    14161 ggcaagtcca tgactagtga acaccaaacg aaagatgaaa tgaagacgga gcagacagct
    14221 agtaaaacaa gcgcagctaa agggaaagag gtggctgatt ttgaattgat gggagtagat
    14281 ggcaagacct accgtttatc tgattacaag ggcaagaaag tctatctcaa attctgggct
    14341 tcttggtgtt ccatctgtct ggctagtctt ccagatacgg atgagattgc taaggatgct
    14401 ggtgatgact atgtggtctt gacagtagtg tcaccaggac ataagggaga gcaatctgaa
    14461 gcggacttta agaattggta taagggattg gattataaaa atctcccagt cctagttgac
    14521 ccatcaggca aacttttgga aacttatggt gtccgttctt acccaaccca agcctttata
    14581 gacaaagaag gcaagctggt caaaacacaa ccaggattca tggaaaaaga tgcaattttg
    14641 caaactttga aggaattagc ctaggaggtg tcctatgaat gataagttaa aaatcttctt
    14701 gttgctagga gtattttttc tagccataac cggtttctat gttctattga tacgaaatgc
    14761 agggcagaca gatgcctcgc aaattgaaaa ggcggcagtt agccaaggag gaaaagcagt
    14821 gaaaaaaaca gaaattagta aagacgcaga cttgcacgaa atttatctag ctggaggttg
    14881 tttctgggga gtggaggaat atttctcacg ggttcccggg gtgacggatg ccgtttcagg
    14941 ctatgcaaat ggtagaggag aaacaaccaa gtacgaattg attaaccaaa caggtcatgc
    15001 agaaaccgtc catgtcacct atgatgccaa gcaaatttct ctcaaggaaa tcctgcttca
    15061 ctatttccgc attatcaatc caaccagcaa aaataaacaa ggaaatgatg tgggaaccca
    15121 gtaccgtact ggtgtttatt acacagatga caaggatttg gaggtgatta accaagtctt
    15181 tgatgaggtg gctaagaaat acgatcaacc tctagcagtt gaaaaggaaa acttgaagaa
    15241 ttttgtggtg gctgaggatt accaccaaga ctatctcaag aaaaatccaa atggctactg
    15301 ccatatcaat gttaatcagg cggcctatcc tgtcattgat gccagcaaat atccaaaacc
    15361 aagtgatgag gaattgaaaa agaccctgtc acctgaggag tatgcagtta cccaggaaaa
    15421 tcaaacagaa cgagctttct caaaccgtta ctgggataaa tttgaatccg gtatctatgt
    15481 ggatatagca actggggaac ctctcttttc atcaaaggac aagtttgagt ctggttgtgg
    15541 ctggcctagt tttacccaac ccatcagtcc agatgttgtc acctacaagg aagataagtc
    15601 ctacaatatg acgcgtatgg aagtgcggag ccgggtagga gattctcacc ttggccatgt
    15661 ctttacggat ggtccacagg acaagggcgg cttacgttac tgtatcaata gcctctctat
    15721 ccgctttatt cccaaagacc aaatggaaga aaaaggctac gcttatttac tagattatgt
    15781 taattaatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgtcttac cgtatgtagg
    15841 gtt
//
LOCUS       DAVDZK010000044        15396 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVDZK010000044 DAVDZK010000000
VERSION     DAVDZK010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15396
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.045"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(54..1220)
                     /locus_tag="VUX16_001802"
     CDS             complement(54..1220)
                     /locus_tag="VUX16_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET8124710.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VELYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            complement(1228..2322)
                     /locus_tag="VUX16_001803"
     CDS             complement(1228..2322)
                     /locus_tag="VUX16_001803"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET8124711.1"
                     /translation="MSKELHLNTILAQAGIKSDDATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAVIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVVFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRYS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(2480..3922)
                     /locus_tag="VUX16_001804"
     CDS             complement(2480..3922)
                     /locus_tag="VUX16_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124712.1"
                     /translation="MRKKVIEGLIYAEKSFFDKNQSGELTSAIVNDTSVIREFLITTF
                     PNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMMFIILPLSNISEKYSRRLQEEIG
                     FLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSFETPFALLFI
                     FATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVYSRSKGSSVA
                     LENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITFSISKGQKIAFVGPS
                     GSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDN
                     LCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGQSQRLQIARA
                     YLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFVLE
                     EGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            complement(3928..4161)
                     /locus_tag="VUX16_001805"
     CDS             complement(3928..4161)
                     /locus_tag="VUX16_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HET8124713.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            complement(4333..6291)
                     /locus_tag="VUX16_001806"
     CDS             complement(4333..6291)
                     /locus_tag="VUX16_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET8124714.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTGRLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDILSVKSGGMLQNFGLEPGEVNEKAKAVGLDTYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAGAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(6493..8115)
                     /locus_tag="VUX16_001807"
     CDS             complement(6493..8115)
                     /locus_tag="VUX16_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET8124715.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGTY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLILIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYIKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLAMGLFVFTVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            8221..9666
                     /locus_tag="VUX16_001808"
     CDS             8221..9666
                     /locus_tag="VUX16_001808"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET8124716.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYHYNSVVFDTICYDSRK
                     AKEKSLFFVKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMEHFSVLKEQAEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGHFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGRKESYPGDTAVAENYL"
     gene            complement(9709..9906)
                     /locus_tag="VUX16_001809"
     CDS             complement(9709..9906)
                     /locus_tag="VUX16_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET8124717.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(10007..10615)
                     /locus_tag="VUX16_001810"
     CDS             complement(10007..10615)
                     /locus_tag="VUX16_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HET8124718.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFSMLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            complement(10640..11152)
                     /locus_tag="VUX16_001811"
     CDS             complement(10640..11152)
                     /locus_tag="VUX16_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET8124719.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPAAFFESNHLYDLYVYPEMDIQSVKERACKHFGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(11239..12174)
                     /locus_tag="VUX16_001812"
     CDS             complement(11239..12174)
                     /locus_tag="VUX16_001812"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET8124720.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELVELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(12245..12544)
                     /locus_tag="VUX16_001813"
     CDS             complement(12245..12544)
                     /locus_tag="VUX16_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET8124721.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(12534..13283)
                     /locus_tag="VUX16_001814"
     CDS             complement(12534..13283)
                     /locus_tag="VUX16_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET8124722.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(13338..13697)
                     /locus_tag="VUX16_001815"
     CDS             complement(13338..13697)
                     /locus_tag="VUX16_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET8124723.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(13699..15099)
                     /locus_tag="VUX16_001816"
     CDS             complement(13699..15099)
                     /locus_tag="VUX16_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET8124724.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYM
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKLEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
BASE COUNT         4676 a         3451 c         2773 g         4496 t
ORIGIN      
        1 tcgcctatga aaatagcctt ctaggaagac ttttctccta gaaggctgga tttttaacat
       61 ttggcaaaag tagccacaat ccgctgacag acttcttgca acagagattt gggcatagct
      121 atattgatgc gggcatggag acttccttcc tctccaaaat ccaaaccacg gttgaggata
      181 accttggctt catttctcaa caactcttgc aatgtttcat cagtcaggtc ataggctgaa
      241 aagtcaagcc aaatcaagta ggtaccttgc ggtttcatga ccttgatttt agtctctttt
      301 ccaaatagat ccaccacata attgatgtgg tcttcaaaga cttgcttgag ttcctctagc
      361 caatctttac cgtatcgata ggcagcttct gtcgccaaat aacccaagcc tgaaatttca
      421 tgctgattat tggccaacag gcgtttctgg aaagccagtc tcaacttagg attttcaatg
      481 actgcatagg aattttttgt tccagcaata ttaaatgttt tagtggcact gctcaagacg
      541 atagcaaaat ttttgaaggc aggattgatg gtattgaaag actggtgttt gtgaccaaag
      601 agggtcaaat cttggtgaat ctcatccgaa actaacaaaa caccgtgttt ttggcagagt
      661 tggccaatct tctccaacac ttctttttcc caaacacgtc caccaggatt gtgagggttg
      721 caaagaatat agagttcaac ctcctcttcc accaaatcct tttcaagttg gtcaaagtca
      781 atctcaaaca gaccatcctt ttccactaag gaattagtaa tcaatctacg attattcaac
      841 ttgacactgc gagcaaaggg tgggtagaca ggcgtgttaa ttaaaaccgc ctcgccttct
      901 tttgtaaagg tttgaatagc tgttgagatg gctggtacca caccctcgat aaagacaaga
      961 gcctctttgt caaagttgta accgtattgt gtagcttccc acttttgaac ttccttaatt
     1021 aagtcttcac tggcataggt ataaccataa accagttggt ctgcgtaagt ttgcacggct
     1081 tggcggattt caggcaagac cacaaagtcc atatccgcta tccaagctgg tagaacttca
     1141 ctatccgttt ctgtttcttt ccatttatag gtatggtgcc ctaaacggtt gggcaggctt
     1201 gtaaaatcat attttcccat ctttgtctta tccttctaag gcttggcgca aatctgcaat
     1261 caaatctcta gcatcctcaa tcccaataga caaacgcaag aggtcatctg tcaaaccata
     1321 agaatagcgt acttctgctg gaatatcagc atgagtttga gtcgttggat aagtaataag
     1381 actttccact ccacccaaac tttccgcaaa agagaagacc ttgagactgt tcaaaatatg
     1441 aggaatgcgt gtttcatcgg ctactttaaa ggaaatcatg cctccacgac cagtgtagag
     1501 aacttcctta actgctggag aatccttcaa aaagacaacc acttcttggg cgttagctgt
     1561 tgagcgctcc atacgaagag acaaggtctt gagaccacga agcaactggt agctgtcaaa
     1621 tggagacaag actgcccctg ttgtattaag attgtaaaaa agcttctcgt atagttctaa
     1681 actattggtc acaaccactc cagccaagac atcattgtgg cctgctagat acttggttgc
     1741 tgaatggaga acgatatctg ctccatcttc aatcggacgt tggtagatag ggctatagaa
     1801 ggtattgtcc accaccactt tggcaccctt agcatgagcc aattttgcta gtttttcgat
     1861 atcaaattcc aacatcaagg gattggttgg ggtttcgata tagagaacat ccacatcctt
     1921 ttctaactcg gcaatcaact cttcttctgt attggcatag gtaaaatgga aacgaccttc
     1981 ctgctccact tggttaaacc agcgaaaaga accaccgtaa agatcacgca ctgccaagac
     2041 cttacttcct actggaaaga cgctaaaggc cagtacaata gctgacatcc ctgagctagt
     2101 cgctagggca tagtctgctg actcaataac cgccaagact tcctcagcct tactgcgagt
     2161 tggattttta gtacgtgtat aatcaaaccc agtagatcga ccaaactctg gatgctgata
     2221 ggtcgttgaa aaatgaagcg gtgtcaccaa tgcacctgtc gcgtcatctg atttaatacc
     2281 cgcctgggcc aaaattgtgt taaggtgtaa ttccttgctc atacaatacc tccaaatcta
     2341 tagtaactat tgtaccactt attttgtatc cttcgttttc ttgttttcaa gagctagtta
     2401 tagtttcaaa ctatataaaa agggagcttt tcctgctccc tttaatagac tataaaatgg
     2461 tgaatctcaa aagacacctt cactctatca tttgctcctg cacaaaacga gcataacgct
     2521 catgattttc tagtaattcc ttatgagttc ctgagccagt gattttcccc tcctctaaga
     2581 cgaaaataca atccacatct tttaccgttg acaaacgatg cgctataatc acaaccgtct
     2641 tctcctttag cacagaatag aggctactga taatcgcata ctcagaatcc gcatcaagat
     2701 tagcagtggc ttcatcaaat ataagaattt cagcatcttt taagtaggct ctagctattt
     2761 gaagtctttg gctttgtccc cctgacaaga gtcgtccgcg ttcaccaact tcagtatcta
     2821 gtccctcttt catggagcga atctcatcac ctagtgatac taagtctagc actttcatca
     2881 attcatcatc agttactaag cgattcaaac cgagacaaag attgtcacga atactgccag
     2941 ataagactgc attattttgt gaaacccaag cgattttact tctccattct tttaagttaa
     3001 aatcatatat acttgattgc tccattagaa tatctcctga aagcggctta taaaaccgct
     3061 ctagcaaacg cacaatcgtt gattttcctg atccagatgg tccaacaaaa gcaatttttt
     3121 gccccttgga aattgaaaaa gtaatatcct ttaagacagg tcgattttca tcataaccaa
     3181 aatagacatg gttaaaattc aacccttgtc ctgataccga ttttcctccc tcaaattttt
     3241 ctttaggaac tgcaagcaag ttctccagtg caactgaaga tcccttgctc ctagaataaa
     3301 cagttacaaa attagctata ttactaatag gattaagtaa ttgaaagagg taaatcaaaa
     3361 acgaaaccaa ggttcccaca gatatatatc ctgcgctgac ccgataaccc ccataggtta
     3421 gcatcacagc tatagtcgca aagataaata agagagcaaa cggggtctca aaagaagtaa
     3481 ccctatctga tttcagtgaa ttgttttgta ccctttcaat acaattatcc aaaacatcct
     3541 gtacactttt ctctgcttgg ttagtcttaa ttaattcatg ttcttgaatc ttttcagtca
     3601 attgccctgt taaaaatccg atttcctcct gtaaacgacg actatacttt tcactgatat
     3661 tggaaagggg caagataata aacatcatac aaggaagagt gatgaataaa agtagagaaa
     3721 gattccaatc aagactaaat aagactacaa tggaaccaag taccataact aaactcagaa
     3781 taatatttgg gaaagtcgta attaaaaact cacgaatgac actcgtatca ttgacaatgg
     3841 cagaagtcaa ctccccactt tggttcttat caaagaagga tttctctgca taaatcaacc
     3901 cctctatcac ttttttcctg atttttgcta tcttttttca cccgattgac taaaaagata
     3961 gtaaccaata gaagaaaaca aggcttgacc aataaaaatc aaaaacgatt gaaatacttt
     4021 ggaacctata ttttcaatag aactcccatc tattaaaccc tttaagataa ggggaagcaa
     4081 caaagcaagt agactagaca gaacaaggaa gaaactcccc ataatcacct tagtatctac
     4141 tcttaataat tttaatttca taaatactcc ttataatatt tcaacggata aagtcaggaa
     4201 taactcaatt tgaggataaa atctaataaa tcttcctata acaaaacgca taacatctag
     4261 gattttatat acctgatatt atgcgttttt aagcacaaag acttcttaca caaacttatc
     4321 tacaattaga ttttatttga catgttttgc caattcttct tgggcttttt tattggattc
     4381 ttctttttct ttcaaccatt tttctctggc ttttgcatat tcgtctgttg tgacaatctt
     4441 atcttgtact ttgaggtatt tatatgattc aacccctttt gtaccggtta aaccataggc
     4501 accagcaaat ggtacggttc ttctcaatga tggggttccc ccacgcgaaa cacttggaag
     4561 aactaaagaa ctatcaatca accaagcttg aatatcagca tatttctcat aacgtttggc
     4621 tggatcttgc tctttattag cttcttccaa catttgagta taggtatcaa gcccaaccgc
     4681 cttagctttt tcattaactt cacctggttc taaaccgaag ttttgcagca ttccgccact
     4741 cttcacactc aagatgtcca gataagttga tggatcttgg taatcaggtc cccaaccgcc
     4801 atgatataaa tcatagtctt tctgagcagc tgtttgagca aaatagcctg aactgtcaaa
     4861 ctcatctgat gttaattgct gaatgtcaat cactacatta tcagaaccta aaacagattc
     4921 aattgattgt ttgatagaac taactccttg tatgcctact ttatctgtta cttccacagt
     4981 cttatccaag tggattggga attgaacacc ctttgcttcg agttctttct tagcttccgc
     5041 aaacttagcc ttggctttct caggattgta gtaagggtct tgaccatccg caaagttgat
     5101 accttgccat tccttaccat agttgaccat cttagaggct acaacttcac caaagtcttt
     5161 tcccttgata ctgacaaagt ttggaggaac cactaggtta cgcaaaatct ttgttgcacc
     5221 ttctttccct tcagactgag ccccataaga tgttctgtca aaagcaaaat tgatagcctg
     5281 acggaagttt ttattgagaa ctgcttcctg agtcgatttc ttttcaatgt cacttgtttt
     5341 agaagtataa ttgtaagact tcctatctag gttaaaatta aagaaatatg aagttgaatt
     5401 ttgcatacta tagatgatat tgtttttgta tttttcttta atcccttcat agctggagct
     5461 gttaggaaaa agacgacccg tagtataagc accagctgta aaattacgtt ccagtgattc
     5521 ttggtcgcta ccatcatagt aggtcaattt cacatcgtct acaaagacat tcttagcatc
     5581 ccagtaatta gggtttttct tatattcaat agcagatttt gagacaagtg ctttcatcaa
     5641 gaaaggtcca ttgtacaaaa tactagatgg atccgccttc ccaaaatcat ccccttttga
     5701 tttcaggaaa tctgcattaa caggaaaaag tatcgttgca agtgtttttg aattccagta
     5761 aagttctggt ttaaccaaag tatattgaac cgtttggtca tcaagtgcct tgacaccgac
     5821 agttgaaaag tcgcttgttt taccagtgat atagtcatcc aaaccagcaa cagagtcctg
     5881 cactagatac aaggcttctg attttttatc agctgcatat tgcaaacctg tcacaaaatc
     5941 ctgggcagtt acaggcgcat attcttctcc ctcagaagta aaccacttgg catccttacg
     6001 aagtttgtag gtataggtca aaccgtcctg agaaacagtc caatcctctg ctaatgatgg
     6061 aataatattc ccatattggt cattttctaa taacccgtct accaaatttg caacaatatc
     6121 ggatgttgct gcgcggtttt ctgctagata gttcaagcta gatggatcac ttgaataaac
     6181 atagttgtat gtttttgacg ccgtgctaga atttccacac gcgctcaata aaactcctgt
     6241 acccaggaca agacctgcca aggttagata tttgctctta gactttttca tttccagaac
     6301 ctcctgcttt aaatatttgt tttattatac aacgtttggt ttgtttagtc aattattttt
     6361 tccaaaaaat cgaaaaaaac tcattttcta tttttgaaag ataattttag ctattttgac
     6421 gctaaaaaag gaataagttc aagttctcct aaaagattgt tcaacttatt ccttttattt
     6481 ataaatgcta ccttacgaaa gcttaaattt tgctcgcagg cgatctgctt gggcttttcc
     6541 tattacctta tctaataaat aggtacgcag actcataacc atataaagtc caccccccat
     6601 ggcaccgaca agagctacat aaaagaagct ccacaaacgt ccacttggtt ggaagaaaaa
     6661 tcctaacagc cactggatgg ttcctattaa cagaaacatg actagggtca gcaaactgat
     6721 taaaatggtt cgcttcaaaa tcaccttgcg cttgacacca gttactttac aaatatcccg
     6781 atacatcaag acgttaggaa tgatgagagc aatggttgtt gaaatcaaag gaccataact
     6841 gtggaagagg gcgatggtag gtagttgcaa gactagcttg gcaatagaac cgtagataaa
     6901 atagagaacg gccttgcggt tgcggaacat ggcctgaagc attggagaca agaccatata
     6961 caagcctaaa ataatagact gcaaaactgt aaagacaaat aagcccatag ccaaactatc
     7021 tggcttacca tagaagaccg tataaagagg ttctcctacc ataaccactc caaccgttgc
     7081 tggtagcaag aacataaaga gtagggtgag actgtcctga acgagacgag aagctgcctt
     7141 caagtccccc ttgatatagt tttccgtcaa aagtggcaaa ccaacactcc caatcgaaac
     7201 ccctacagaa atcaaaatca tcgtgatttt attaggattg gctgagaaat aagaaaacat
     7261 gacaaccaag tcctcattac tgtagttggt aaaccagctc atactattga taaaggtcag
     7321 ctgatccaaa atctgaaaga gctggatggc agaccctgtc aggataaaag gaatggcttc
     7381 cttaatggta tcaaccaaga gacgcttact gttaatctta tctcctgttt caaagactct
     7441 tttgagtgaa ccttcttggg caaggaaata aatcaagact gcaaaactgg ctaccatacc
     7501 gacaaaggca gcaaaggttg attgggtaac ggctgctaga taatctcctg aaccgagctt
     7561 cataatgata aaggttgcta ggagcatcca gataacacga atgacctgct cagcaatttg
     7621 actcatggca taaggtttga ggttattcat cccttggaaa aatcctcgga taacactcat
     7681 agacgggaaa atcaagactc cccaagccaa gctttgcatg attaggatca agtctttgcc
     7741 cacgccagac aagtctgcta gccaaggagc aaagacatac aagactaaag caaaaaccag
     7801 acctagtcct gtcataaagc ctaagaagct ccgaatcagg gcaaagctat gctcttcttc
     7861 tcgcatagta ttatacttgg caacttgctt ggccaccgca actggaatcc ccgctgttga
     7921 aaccaacaag aaccaagcat agatattgta acccatggta aagagaccat ttgccttagc
     7981 tgcataagtc cccatccaga tgtaccaagg gataatgtaa acagccccga gtaggcgact
     8041 gataaagtta ctagccgtta gccaagcagt cccccgtaac atctgagcct gctggtgatt
     8101 gttttcgtgc gacatagatt cctcattcaa ttttgataac taggaaaaac tccttatctt
     8161 ccattataaa cttttccttg ttacttgtaa atttgcgact ttcggtttac aatagaaagt
     8221 atgataaaaa ttgaaaccgt attagatata ttaaagaaag atggtctctt ccgcgagatt
     8281 atcgaccaag gacactacca ctaccactac aacagtgtcg tctttgacac catctgctat
     8341 gacagccgca aggccaaaga aaagagccta tttttcgtca agggcgctgc ctttaaaaaa
     8401 gaataccttc tttctgctat aacacaaggc ttagcttggt atgtagctga aaaggactac
     8461 gaagtcggta tccctgtcat cattgtgaac gatataaaga aagccatgag tttgattgcc
     8521 atggagttct atggtaatcc acaggaaaaa ctcaaactcc ttgcctttac tggtactaag
     8581 ggtaagacaa cagcagccta tttcgcctat aacatcttat ctcaagggca tcgacctgct
     8641 atgttgtcga ccatgaacac aactcttgat ggcgagactt tctttaagtc agcgttgaca
     8701 acccctgaga gtattgacct ctttgacatg atgaatcagg ctgtgcaaaa tgaccgtacc
     8761 cacctcatca tggaagtctc cagtcaagcc tatctggtca aacgtgtcta tggtctaacc
     8821 tttgatgtgg gagttttcct caatatcagc ccagaccata tcggcccgat tgaacaccct
     8881 agctttgaag actatttcta ccacaagcgt ctcttgatgg aaaatagccg agcagtcatc
     8941 attaacagtg acatggagca cttctcagtc ttgaaagaac aggctgaaga tcaagaccat
     9001 gatttctatg gtagccaatt tgataaccaa atcgagaatt ccaaagcctt tagcttttca
     9061 gctacgggta aactcgctgg agattatgat atccaactga ttggtcactt caaccaagaa
     9121 aatgcagttg ctgctggact tgcttgtctc cgtctcggag caagtcttga ggacatcaaa
     9181 aaaggcatcg ctgcaacccg cgttcctggt cgtatggaag tcctcactca gaaaaatgga
     9241 gccaaggtct tcatcgacta tgcccacaat ggggatagtc tgaaaaaact catcaatgtg
     9301 gttgaaactc atcaaaccgg aaagattgct ctggttctgg gatcaacagg aaacaaggga
     9361 gaaagtcgtc gtaaggactt tggcctcctc ctcaatcaac accctgagat tcaagtcttt
     9421 ctgactgctg atgaccctaa ctatgaagac ccaatggcca ttgcagatga aattagtagc
     9481 tacatcaatc atcctgttga aaagattgcg gatcgccaag aagccatcaa ggcggcaatg
     9541 gctatcacaa atcacgaatt agatgcagtt attattgcgg gtaagggagc cgattgttac
     9601 caaatcatcc agggcaggaa agaatcctac ccaggagata cagccgtcgc agaaaattat
     9661 ttataagaat agaaaaaatc aagggaaaat gaaacccttg attttttcct attctttagt
     9721 aaaaacgttt ttcaaacctt caacggcacc ttctacagca ccttttgcgt cttctacaac
     9781 gtcttttgcc ttagcaactg ttttttcaac agctccttca agttctgtct tgctgtctcc
     9841 agtaacttta ccaaaacctt ctttgacagc gcctgttgct tgttccaatt tgttttcaag
     9901 tgacatatga ttgtctcctt tagtttattc cgatatgtgt taccggttac atatagttta
     9961 taccgaatac taaggaaagt caaacaatgt gctcagaaac aagaaatcac gctaagtaga
    10021 aagttaatct ctccttatca aaatcgatag ccaactcata ctttccatct tcattttgca
    10081 caatatagcc taagacaacc aaactgtcca caaagatatc acggcatttc tgcataagct
    10141 ggtctttttt gagaaatttc aacaaaaaag ccgtcatata cttgagggca tactcaggat
    10201 taacatctcc taaaatgtca tagagctcct gctgtttttc tgtcaaagga tactgctgtt
    10261 tgaccttgta aaaataattg gacagggtca ttttaatgcg cgcaaagtcc gtcttttcaa
    10321 ctaaaatagc tgcattgatt tgattgcgca attccgtctc aaaactctgc tccaacaagg
    10381 cttgatagac cggactagct tctctgacaa aaatctcttg atccagttca agactatcaa
    10441 gtgattcaag catagaaaaa ttgaggtaat agcgtttatt ttcacgtaga atcaagcctg
    10501 cctttatata ctcttccatg agtttatcaa ctgcaacatc tggaaattga gccttaattt
    10561 cccgtagaat cacatcctca tactggtcca gatatcggat caattctcca aaaatggctg
    10621 tctcgtcaaa cgagatggat taaaaatctg aatcatgaag attcctttct ttacattgta
    10681 acagaggcga tgctgccaac tgactaggat tggtaccagc ttggttcaga ggaacaggca
    10741 gacctagttc tatgtaatac tccctccaaa aatcactaat ctcctgctcc ccatctccaa
    10801 atttcatagg aatagtttca aaaataggta ggatttctgc tatatactgg gagcagtaga
    10861 aaccagctgc atctggatag aaagaagcat tgtagggtgc tccaaaatgt ttgcaagctc
    10921 tttccttcac cgactggata tccatttctg ggtaaacata gaggtcgtac aaatgattgg
    10981 actcaaagaa ggctgccggt tcttgacaga caacaccagc ctgtccacta gcatgataaa
    11041 tcatcccatc caaataaatg gcaacatggc tatagttacc tgtggaagtc tggatggcct
    11101 gtcccatgtc tgacccatct ctcacaaaaa tcaaatcacc attttctaac atacttcact
    11161 cctagaaaaa aaggagccga aactcctttc gatataaggc aaactagcct ttccgatttt
    11221 gagctgacac ccaaaatctt acgcattaaa gctttcagtc aattgaggta ccacttgttt
    11281 cttacgtgaa acggcaccag caaggaaggc atgattgttt tcaagtttga agttgaaagc
    11341 cgcttcgacc ttgtccatat tggcaccaag agccaagatt tctgagtttg agttgacgat
    11401 atctgtaatc atcaagacaa agtcagagta gccgtttgat tcgttggcag cttgcattgc
    11461 agcttcaatt tctgcttggc gttccaaaac ttcagcgatg tcaactgtgt tcacttgggc
    11521 aacacggaca ttatttccgt tgagttcaaa agtcttagca tcgatgtcaa tcaattcttc
    11581 agcagatttg ctagccaagt tggtaccagc tttcaacatt gccaaaccat attcttccaa
    11641 gttcacacca gccaattcaa ccaattcagg agcaatgatt ttatctgttg ggtgtgttgt
    11701 tggtgatttc aaaagaaggg tatctgaaat caaacctgaa agcatcaaac ctgcaatctc
    11761 tttaggcaca gctacaccat gttctttgaa catacggtaa acgattgaag acgctgatcc
    11821 aactggctcc aaacgcatgt aaagtgggct tgcagtttca aagttagcca cacggtggtg
    11881 gtctacaaca ccgtaaactt ctacttcagc gatatctgat acagattgtt ggaattcatt
    11941 gtggtcagtc aagataactt gctctgcccc ctctgctttg gcagaagtga taacacgtgg
    12001 tgcttccaca ccaaaatagt tcaagacaaa ggctgtttct tcatttggag ttccaagggc
    12061 aacagcttcc gtatccaaac cgtaagcttc ttttgcaagg taggcaaaag ctacagatga
    12121 cccgatggca tctgagtctg gattttggtg accaaatact agaatcttgg acatggtaat
    12181 acctcatttt gtttattttc tttattgtag catttttttc gctttttgac aaaggtaaga
    12241 ggagtcaaag gactccccac gattcttcaa aataactgag taaatttcta tcttgatttt
    12301 cagataaaaa ttcttccttc tgtggcctct tcttacgctt gagaagagcc tcagccgaca
    12361 tggcttcttc cttactggca aaaccttgag catagataag tttgactggc aagcgtgctc
    12421 gtgtatattt ggctcccttc ccactattgt ggatagcgag gcgtcttctc acatcagtcg
    12481 tatagcctat atagtaggat ccatcacgac actccagaac gtacatataa gccttatgat
    12541 ccataataaa tctcttcgat ttcgggcgta taagagccat catcattgtg gacaatcaaa
    12601 ggaggtaaga ccttaaagcc acttgttgag ccatccttga tcgcctcaat caaaagcata
    12661 ttggcttcct tttctctttt tggataaaca aactgcaggc gcttaggggc tagattatgt
    12721 cgttttaacg tatccaaaat atccagaagt cgatcaggac gatgaaccat ggccaaacgc
    12781 ccattagact tgagaatact ctgggcacta cgacagattt cttccaaatt agtcgtgatt
    12841 tcgtgtcgag ccaagagata atgttcactc tcgttcagat tagaataagg atccaccttg
    12901 aaatatggtg gattacacaa aatcatatcc accttactcc cctgaatgtg agcaggcata
    12961 tttttcaaat catcgcagat gacctgcatt tgctcctcta atccattcaa acggacagag
    13021 cgttcagcca tatccgccaa acgctcctga atctcaacag acaatatctg tgcttgagta
    13081 cgagtgctag caaaaagccc cactgctcca ttcccagcac agaaatccac aatcaacccc
    13141 ttcttaggaa aacgtggaaa tcgtgataag agaacactat ccaccgaata gctaaaaacc
    13201 tctctatttt gaatgatttt gatatctgtc gaaaagagct ggttaatgcg ctctcctgat
    13261 tttaataatt gttcttcttc catggtccta ttataataaa tttatattaa cattacaaaa
    13321 aaatataaaa ctctaaacta cttcttcttt tttaaatggt gcagagcttc tccagtccag
    13381 attggtagca ttcgtcgaaa gggagcaaaa ccgtagttaa agcggtcgct tgaaaagcgt
    13441 ctccgtctag gaaactggta cttttcttcc tccaaagtgc ggatagaaag actggctttc
    13501 cccgtaaatt catctaaatc cactacctga acttgaacct cttcatcgac tttcaaggtt
    13561 tcatgaatat tttcaataaa tcctgtccga atttctgaaa tgtgaatcag ccccgtatca
    13621 cccgtctcta actcaacaaa ggcaccgtag ggctgaatcc ctgtaatacg cccctttagc
    13681 ttatcaccga ttttcatctt agtcctcgat ttcaatagtt tcaattacaa catcttcaac
    13741 tggcttgtcc atagctcctg tctcaacagc agcaatggca tccaagacag cgtaagatgc
    13801 ttcatcagct aactgaccaa aaaccgtgtg acggcggtct aggtgaggtg tcccaccttg
    13861 attggcatag atttctgcaa tcggttctgg ccaaccacca cgagtaattt ctttcttcga
    13921 ataaggtagg tgttggtttt gcacgataaa gaactggctg ccgttggtat ttggaccagc
    13981 atttgccatg gaaagagcac cacggatatt gtaaagctct tctgagaatt catcctcaaa
    14041 agattcgccg tagattgact cgccacccat accagttcca gttgggtctc caccttggat
    14101 cataaagtcc ttgataatac ggtggaaaat gacaccatca tagtagccat cttttgaaag
    14161 agatacaaag ttagccactg ttttaggagc atgttcaggg aaaagcttga tacgtaagtc
    14221 tccgtgattg gtcttaatag tcgcaagagg accttctact gtttcaatat ctacttgtgg
    14281 aaaatgcaat tctttttcta ccataccaaa tacttctaag gcatcaaaaa tgccatcttc
    14341 ttctaatgtt tttgtaatat aatctgcttt ttctttgatt ttatcatgag aaattcccat
    14401 ggcaacgctg attccagcat aatcaaagag ttccaagtca ttgagaccat ctccaaaaac
    14461 catgaccttc tctagtttca agccaaggtg ttccacaacc ttttccaccc ccgtcgcttt
    14521 ggagcctgaa atcggcacaa tatcagacga atgttgatgc caacgaacca tgcgaagttt
    14581 gtctgagaga ctgtcaggca agtgcaagtc atctccctta tcttcaaaag tccacatctg
    14641 atagatatct tctttttcat ggaaatcggg atctacatct aagtcgggat aaattggatt
    14701 gatagcttca ctcatcatat cggtgcgagt cgacaacttg gcatcatgac tcccaaccaa
    14761 gccatactca attccttctt gcttagccca agacatatac tcctcaacat ctgacttttc
    14821 aatctgatgc tgataaatga cctgaccttt tttatcttcg atataagccc cattcaaagt
    14881 tacaaaaaag tcaggcttga gatcacgaat ctctggaaca acaccaaaaa tgccacgtcc
    14941 agaggcgatt cctgttaaaa ttcctttttc acgcaactgt ttaaaaacag tgggaattgt
    15001 agttggaata aaccctgtct ttgaattccg caatgtatca tcaatatcaa aaaagacaat
    15061 cttgatcttc tttgccttgt atcttaattt cgcgtccatc tcactacctc tttcaatcta
    15121 actctttcca ttatatcata aagtaggcaa atcccctatt ttcaaaaagt ttatcatttt
    15181 tattttaatt tcttggatga gaaaagagac atatttatga aaaagtccaa ccaaattcaa
    15241 ctcgacttct cattccagaa ctcgtaaaaa aaaacctaat atccagattt tagacatcat
    15301 caagaaggat acacacaagg aaatcatcgc caaactggac tacgacgccc catcttgccc
    15361 tgagtgtgga aaccaattga agaaatatga ctttca
//
LOCUS       DAVDZK010000045        15122 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVDZK010000045 DAVDZK010000000
VERSION     DAVDZK010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15122
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.046"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(126..416)
                     /locus_tag="VUX16_001817"
     CDS             complement(126..416)
                     /locus_tag="VUX16_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124725.1"
                     /translation="MLEQIIQSLFIIVAIGLILLVLYQIAKILGSLFVIGLLGLLAFM
                     EIYGIYLFFTERYLYVEDLAANGILSFTTFYIGFNVLLIFGLVAKVIRSRMA"
     gene            complement(431..730)
                     /locus_tag="VUX16_001818"
     CDS             complement(431..730)
                     /locus_tag="VUX16_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124726.1"
                     /translation="MTQTVEEQRYQLEEWLAKGFTSPEDRANYQALKEQYEDETLDYS
                     FSKREIIGQLDIIITTRENNFPDLDEVTKESYIDLIAQLDDLDKGQANYYRKQLV"
     gene            complement(800..7603)
                     /locus_tag="VUX16_001819"
     CDS             complement(800..7603)
                     /locus_tag="VUX16_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET8124727.1"
                     /translation="MIQEQLLEMLRARLPRDQILLESFLRYQAVHFDEDWESLIQDFT
                     THRGVVPSPDQVVRFETEVSAFVKASPFDEATDLSSYTRTFGQAGLKKLPQLNSDEKA
                     LVIEVALFNLATRFQLLDQEGAYQSISVASLLEKGKAANLVNVYRVANNLSDRISRDI
                     EQFLLTYEPELDTRPIETISESDEIEVEPSPEITFREESFVIMASLEEDLSQLNLRTG
                     KTEHLPAYEHLNLSQKFEILSHFDQVRNSRPKLPNLRRGEFDHEMEMMPIYEEEELLI
                     YLEADGTIYDLQRPLTPQEEVILTEIGQTILAENTEKLTSLGIDLANFDENKQGVLID
                     ATGRFRLKNADLALLGGYPNASVTQLALTTELLQMGLTHDRAEFFLTSQLKLEDLRPI
                     AYAFLHEYLDIEEARTFERDKQSQPDVSFRDWRERLTQTESEIIMPQETPQNPIVEEA
                     LKRYPIDSTVSYKGEDLKVIAIEESGVNDLIRIELQNDFTDVIEQNPVLFLRTLEEIT
                     QALHLPSAEEKEEVKQPSQELDLFSFMLDDENQEDVFQEPVMEKEVEKSETLEEEIDS
                     ELFEVIEMTPTTDFHFPEDLTNFYPKTTRDKVETNVAAMRLVKALEAEERQATPDEQE
                     LLAKYVGWGGLANEFFDEYNPKFSKEREALKTLVTDKEYSDMKQSSLTAYYTDPALIR
                     QMWEKLEQDGFTGGKILDPSMGTGNFFAAMPKHLRENSELYGVELDTITGAIAKHLHP
                     NSHIEVKGFETVAFNENSFDLVISNVPFANIRIADSRYDKPYMIHDYFVKKSLDLVHD
                     GGQVAIISSTGTMDKRTENILQDIRETTDFLGGVRLPDTAFKAVAGTNVTTDMLFFQK
                     HVDKDYQAYDIAFSGAIRYDKDDRIWLNPYFDGEYNPQVLGTYEVRNFNGGTLSVKGN
                     PDNLIADVQIALKQVKAPRVVEPSDIFINSDVLARQVIDTSIPADIRESLEQYSFGYK
                     DSTVYYRDNKGIRVGTKTEEISYYVSEEGHFKAWDTKHSQKQIDRFNALEVTDSTALD
                     VYVTEEPAKRGRFKGYFKKTVFYEAPLSEKEVARIKGMVDIRNSYQEVIAIQRYYDYD
                     KDEFNHLLGKLNRRYDNFVKRFGYLNSPVNRNLFDSDDKYSLLASLEDEGLDPSGKTI
                     IYTKSLAFEKALVRPEKEVTEVSSALDALNSSLADGRGVDLDYMMSIYQTDSKASLIE
                     ELGDAIIPDPEPYLNDREVVYVSRQDFLLGDVVTKLEIVDLLIKEDNSDFPWVYYQGL
                     LEDVKPPRVTLADIDYRIGSRWIPLAVYGKFAQETFMGQTFDLTAPEVSTVLEVSPID
                     GTMSYQSKFAFRYSTATDRSLGVPGSRYDSGRKIFENLLNSNQPTITKQVEDGDKKKH
                     VTDVEKTTVLRAKETQLQELFQDFVASYPEVQQMIEETYNSFYNRTVSKVYDGSHLTI
                     DGLAQNISLRPHQKNAIQRIVEEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLY
                     VVPSSLTAQFGQEIMKFFPTKNVYVTTKKDFARAKRKQFVSRIITGDYDAIVIGDSQF
                     EKIPMSQEKQVAYIQDKLDQLREIKQGSDSDYTVKEAERSIKGLEHQLEELQKLERDT
                     FIEFENLGIDFLFVDEAHHFKNIRPITGLGNVAGITNTTSKKNVDMEMKVRQVQGEHD
                     YRNVVFATGTPVSNSISELYTMMSYIQPDVLERYQVSNFDSWVGAFGNIENSMELAPT
                     GDKYQPKKRFKKFVNLPELMRIYKETADIQTSDMLDLPVPEAKVIAVESELTEAQKYY
                     LEELVDRSDAIKSGSVDPSEDNMLKITGEARKLAIDMRLIDPAYTLSDNQKILQVVDN
                     VERIYREGELDKATQMIFSDIGTPKSKEEGFDVYNELKDLLVDRGIAKEAIAFVHDAN
                     TDEKKNSLSRKVNSGEVRILMASTEKGGTGLNVQSRMKAVHHLDVPWRPSDIVQRNGR
                     LIRQGNMHQEVDIYHYITKGSFDNYLWQTQENKLKYITQIMTSKDPVRSAEDIDEQTM
                     TASDFKALATGNPYLKLKMELENELTVLDNQKRAFHRSKDEYRHTISYCEQNLPALEK
                     RLSQYDLDIAQSLATKSQDFVMRFDNQMMDNRAEAGDYLRKLITYNRSETKEVRTLAN
                     FRGFELKMATRSPSEPLPDMVSLTISGSNQYSVSLDLKSDVGTIQRITNAIDHILEDQ
                     EKTEKMANNLKDKLAVARVEVEKVFPKEEDYQLVKAKYDILAPLVEQEAEVEEIDAAL
                     AKFNETTQPKKDLQLSLDI"
     gene            complement(7655..8206)
                     /locus_tag="VUX16_001820"
     CDS             complement(7655..8206)
                     /locus_tag="VUX16_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124728.1"
                     /translation="MAWNYDTISKTLSEMAQENYEDMVKALLTMELSIKSKSLLDRLY
                     QDFMGIDDLSLVSDDLRLRADGYQEQLQEELTDLLDKLYRTGEGASFIMEVIASNNIF
                     DTLVQYEVLDEDDYSSLTLETLQDIIQKDLPLTSQDYFGDVTYLALQKDLLDQKSHFL
                     QQYVTTLVDKLPQEKDQSTLVLD"
     gene            complement(8190..8381)
                     /locus_tag="VUX16_001821"
     CDS             complement(8190..8381)
                     /locus_tag="VUX16_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003093624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding protein"
                     /protein_id="HET8124729.1"
                     /translation="MEPKSIYTMDSDQDGLTDAQELALGTNLFSSDTDSDGLTDLEEV
                     QQGLNPIQQGKESSYGLEL"
     gene            complement(8382..13286)
                     /locus_tag="VUX16_001822"
     CDS             complement(8382..13286)
                     /locus_tag="VUX16_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET8124730.1"
                     /translation="MTKQCHHHFLVNQEQAEKHVFRKSKKYRTLCSVALGTMVTAVVA
                     WGGQVAQADEVTMPPLDKTVQLTENNATNLPEAQPAPVAEQTDSLASTGQSDGTITVT
                     VPHDTVTNAINQATAEGVTTVQDQPMDLGNTTSASDTSKQLDKAEADAAKQAEDITRV
                     TNTYKADKAAYEQDKTRVEKGNAALVASHKEATQAGKALNSSVDTTASEVQTQDKSAN
                     VTITTQTVPSGEGSTVSGYQDYTSAVAAIDKQNKASLADYITKKQAADAITAKNLAVQ
                     KENEAGLANAKAENEAITKRNQAEQKAIDDENKAGQAAVDTYNKNQQKLVTDREAEIA
                     AIIKRNKEKEEAAKKENEAIDAYNAKEMNRYKRDLADISKGEEGYISQALAQALNLNN
                     GEPQARHSADTRNPNRIIAKGDAMLGGYSKILDSTGFFVYDTFKTGETLSFTYQNLQN
                     VSFDGKKITKVAYDITNLVSPTETDSVQLVVPNDPTEGFIAYRNDGTGNWRTDKMEFR
                     VKAKYFLEDGSQVSFSKEKPGVFTHSSLNHNDIGLEYVKDTSGKFVPINGSTIQVTDE
                     GLARSLSSNRASDLNLPEEWDTSFSKYAYKGAIVSTVTSGNTYTVTFGQGDMPQNAGL
                     TYWFALNTLPVARTVKPYSPKPHVSPKLDPVPEPIKVVPKTFTPKTFTPEPPVIFKEK
                     PLEKVTQPRLTLTKVTFAKEPRSEPLPKAPQVPTVHYHDYRLTTTPEIMKKVVNTDQD
                     NLHDKTIAKDSTVIYPLTVDVFSSNRAKTTTLTFEDYLPAGYAFDKEKTQAENGNYTL
                     TFDEAKNFVTLTAKEALLQEVNQDLTKSYQLVAPKLYGSLQNDGATYSNSYKLLINKG
                     TSNAYTVTSNVVTVRTPGDGKITSRITPQKRNENEDGVVINDTVVALGTTNHYRLTWD
                     LDQYKGDTSSKETIARGFFFVDDYPEEVLDLVDKGTSITTLDGKAVSGITVKAYASLS
                     EAPKDLQDKLAHAKISPKGAFRIFQPNDNQAFYDQYVKTGTSLNLLTKMTVKDSLYGQ
                     TKTYRNKAYQVDFGNGYKTNEVTNTLVSPTPKKQNLNKDKVDINGKPMVVGSQNYYTL
                     SWDLDQYRGIKADKAQIAKGFYFVDDYPEEAVLPDDTAIQLTTSNGKAVIGVTVKNYT
                     SLSEAPKPLQASFEKRKIAPKGAFQVFMAEDPQAFYDSYVTKGQNITIVTPMTVREEM
                     LNSGKSYDNVAYQVDFGQAYETNTVTNHVPKVNPHKTNTNKEGVSIDGKTVLPNTVNY
                     YKIVLDYSQYKDLVVTEDTLAKGFYMVDDYPEEALTLNADGVQVMDKAGNLVKGISVK
                     AYASISEAPQVVQEAMAKRQLTPKGAIQVLSADDPKAFYETYVKTGQTLVVTLPMTIK
                     NELTKTGGKYENTAYQIDFSLAYVTETVVNNVPKLDPQKDVVIDLSQKENSLDGKEVA
                     LNQVFNYRLVGALIPGNRATPLIEYRFDDDYDESHDDYNGVYKAYTVVDVTLKDGTVL
                     LKGTEVTKYTLQHVDTSQGTVTISFDKEFLEKLAEESEFQADVYLQIKRIASGEVENT
                     VLHTVNGYTISSNTVKTTTPEPEPPTPNQPTPPQPLIPTQEPPVPASVLPNTGESQSL
                     LALVGGGLLLGLAYVLAKRKMEDN"
     gene            13480..14070
                     /locus_tag="VUX16_001823"
     CDS             13480..14070
                     /locus_tag="VUX16_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET8124731.1"
                     /translation="MSKKELLLEYINNHNGLITHRDCKKLGIPTIYLTRLEDEGVIFR
                     VEKGIYLSSSGDYDEYYFFQYRYPRTVFSYISSLYLQGLTDEIPQYFEVTVPKDYRFR
                     NRPLNLNSYTVSKDIINMGVTSVKTPMGNTVNVYNFERVLCDFILNRSNIDNELFVKT
                     VQTYSNFPEKNLAKLYDYAQKLNILDDVKRTLEVLL"
     gene            14067..14912
                     /locus_tag="VUX16_001824"
     CDS             14067..14912
                     /locus_tag="VUX16_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HET8124732.1"
                     /translation="MNKAKLTALCHNISKQTGLTFNSVMTYYFLEVILKKLSRSSYAD
                     HYIFKGGFLLSNIIGVESRSTVDIDFLFHKQTLSEENVQQQLEEILSEVKNDIQFSIQ
                     SITTIKESDDYGGYRATILCQLENIKQIIHLDIATGDVVTPQPITYDYKAIFNDENFP
                     IIAYTIETVLAEKLQTIYSRSFLNSRSKDFYDIYILSKLKKDDIDLAQLKMACEKTFS
                     YRETELNFNNIIQLLETFKSDSTQQQQWQNYSKKYSYTKGISFSEILDEMIRLVSLLI
                     SLNNE"
BASE COUNT         4096 a         3212 c         2974 g         4840 t
ORIGIN      
        1 ataggaaatc gaacgacgga gcgactactc ctagggagat ttatcttttt ccacagagtt
       61 gtaggcaagt tcagttttca agatacaaat cattagaaga gtctgggaca atagtctcca
      121 ttattttatg ccatccgact tctaataacc tttgccacaa gtccgaatat aagtagcaca
      181 ttaaatccaa tatagaaagt ggtaaaactc aaaataccat tggccgctaa atcttcgaca
      241 taaaggtatc gctctgtgaa aaagagataa atgccataga tttccataaa ggctaggagg
      301 ccaagcagtc cgataacaaa cagacttcct aatattttcg caatctgata gaggacgagc
      361 aaaatcagcc ctattgctac gataatgaaa agactttgaa tgatttgttc taacatatct
      421 acgcctcttt ctacactaat tgcttacggt aatagttagc ctgcccctta tctaggtcat
      481 caagttgagc aattaagtca atatagcttt ctttggtcac ctcatctaag tctggaaaat
      541 tattttcacg agtggtaata atgatatcta attgaccaat gatttctcgc tttgaaaagc
      601 tgtaatcaag ggtttcatct tcatattgtt cctttaaggc ttggtagtta gctcggtctt
      661 cagggcttgt aaaacctttt gctagccatt cttctagttg gtatctttgt tcttctactg
      721 tttgggtcat gttctgttct cctttggtga tttcttaatg tcattttacc gcgttcaaaa
      781 ctatttgtca gcctttttat taaatatcaa gagaaagttg aaggtctttt ttcggttggg
      841 tcgtttcatt aaatttagct agtgctgcat caatttcctc aacctctgct tcttgttcta
      901 ccaagggagc taatatgtca tacttagctt taaccagctg ataatcctct tctttaggaa
      961 aaaccttctc tacttcaacc cttgcgactg ctagcttatc ttttagatta ttggccattt
     1021 tttctgtttt ttcttggtcc tctaggatat ggtcaatggc attagtaatg cgttggatgg
     1081 ttcccacatc tgatttcaag tctaaagaga cagaatactg gttgctacct gaaatggtta
     1141 aagacaccat atctggcaac ggctcactag gacttctggt tgccatttta agctcaaatc
     1201 ctctaaaatt agccagtgtt ctcacttctt tggtttcaga acggttatag gtaatgagtt
     1261 ttcgtagata gtctccagct tctgcacggt tatccatcat ttgattgtca aaccgcatga
     1321 caaaatcttg tgacttagtt gccaaagatt gagcaatatc aaggtcatat tgactgaggc
     1381 gtttctcaag ggcagggagg ttctgctcac agtaagaaat ggtatggcga tactcatctt
     1441 tggagcgatg aaaggcacgc ttttgattgt ccaataccgt caactcattc tctagttcca
     1501 tcttgagttt cagataagga ttacctgtcg ctaaagcctt aaagtctgaa gcggtcatgg
     1561 tttgttcatc aatgtcttct gccgaccgta ctgggtcttt agaggtcatg atttgcgtga
     1621 tgtatttgag tttattctcc tgagtttgcc agaggtagtt atcaaatgac cctttggtaa
     1681 tataatgata gatatctacc tcttggtgca tattgccttg acgaattaac ctaccattgc
     1741 gttggacaat atcagaggga cgccagggaa catctaaatg gtggactgct ttcatacgtg
     1801 actgtacatt taatcctgtt ccaccttttt ccgtagaagc catgagaatc ctgacttccc
     1861 cactattgac cttgcgtgag agagagtttt tcttctcatc cgtattagcg tcatgaacaa
     1921 aggcaattgc ttctttggca atccctctat ccactaagag gtctttcaat tcattgtaaa
     1981 catcaaaccc ttcttcttta cttttaggcg ttccaatatc agagaaaatc atctgggtag
     2041 ccttatcaag ctcaccctca cggtaaatgc gttccacatt gtccaccact tgaagaatct
     2101 tctgattgtc cgataaggta taggctgggt caatgagacg catgtcaata gctagttttc
     2161 tagcttcccc agttatcttt aacatattat cctcactagg gtcaacgcta cctgacttaa
     2221 tggcgtctga acggtcaacc aactcttcaa ggtagtattt ctgagcttct gtgagttcac
     2281 tctccaccgc aatgactttg gcttcaggta caggtaaatc aagcatatct gaggtctgaa
     2341 tatcagctgt ttccttataa atccgcatga gttcaggcag gttcacaaac ttcttaaagc
     2401 gtttcttagg ttggtactta tctcctgttg gggcaagttc catagaattc tcaatattcc
     2461 caaaagctcc cacccatgag tcaaagtttg agacttgata gcgttctaag acatctggtt
     2521 ggatataact catcatggta tagagttcac taatagagtt agagactggt gttcctgtcg
     2581 caaagaccac attacgatag tcgtgttctc cttgaacctg tctcactttc atttccatat
     2641 ccacattctt tttagaggtc gtgttggtaa ttcctgcgac attaccaagt ccagtaatgg
     2701 ggcgaatatt cttaaaatga tgagcttcgt ccacaaagag aaagtcaatc ccaaggtttt
     2761 caaactcaat aaaggtatct cgctccagtt tttggagttc ttccaattgg tgctccaacc
     2821 ccttgataga acgctctgct tctttaaccg tatagtcact atcactgcct tgtttaatct
     2881 ctcgtaattg gtccagctta tcttggatat aggcgacctg cttttcctga ctcatgggga
     2941 ttttctcaaa ctgggaatcc ccaatgacaa tggcatcgta gtcccctgtg atgatccgtg
     3001 agacaaactg cttacgtttg gctctcgcaa aatctttctt ggtcgtcacg taaacattct
     3061 tggttgggaa gaacttcatg atttcttggc caaactgagc ggtcagactt gatggcacca
     3121 cataaagagg cttatgcacc atacccaatt ctttcagttt gaatcctgcc ccaagcatgg
     3181 ttaaggtctt acctgaaccc acttcatgag ctagaagcgc tcgtttttct tccacaatgc
     3241 gttgaatagc attcttctgg tgagggcgaa gagaaatgtt ttgtgctagc ccatcaatgg
     3301 ttaaatggct gccatcataa acttttgaga ctgtacgatt ataaaagcta ttataggtct
     3361 cttcaatcat ctgttgcacc tctgggtaac tagccacaaa atcttggaag agttcttgaa
     3421 gttgtgtttc cttagcacga agaaccgttg tcttctccac gtccgtcaca tgctttttct
     3481 tatccccatc ttccacttgt ttggtaatgg ttggttgatt ggaattaagc aggttttcaa
     3541 agattttgcg accactatca tagcgtgacc caggaacacc taaacttcta tccgttgcgg
     3601 ttgaatatct aaaggcaaac ttagattggt aggacattgt gccatcaatc ggactaactt
     3661 caagaacagt tgatacctct ggggcggtca ggtcaaaagt ttgtcccata aaggtttctt
     3721 gggcaaattt cccataaacg gctagaggaa tccatcgtga gccaatccga taatcaatat
     3781 cagctaaagt cacacgtggt ggtttcacgt cttctaagag accttgataa tagacccaag
     3841 gaaaatcaga attgtcttct ttaatgagta agtccactat ctctagctta gtcactacat
     3901 ctcctaataa gaaatcctgc cgcgacacat ataccacttc cctatcgttt agatagggtt
     3961 ctgggtctgg aataatagcg tctcccaatt cctcaatcaa agacgctttg gaatccgtct
     4021 gataaataga catcatataa tccaaatcca ccccacgacc atctgcgagg ctggaattga
     4081 gagcatcaag ggcagaagac acctctgtta cttccttttc gggacgaacc aaggcttttt
     4141 caaaggcaag tgacttggtg taaatgatag tcttaccact tgggtcaagt ccttcatctt
     4201 ctagactagc aaggagcgaa tacttatcgt cactatcaaa tagattacgg ttcacaggac
     4261 tattcaaata tccaaatcgt ttaacaaagt tatcatatct gcgattgagt tttcctagca
     4321 agtgattaaa ctcgtctttg tcgtaatcat agtagcgttg aatggcaatc acctcttggt
     4381 agctatttcg aatatcgacc atccctttaa ttcgtgccac ttctttctca gacaaaggag
     4441 cctcataaaa gacggtcttt ttgaaatacc ccttaaatcg gccacgcttt gcaggttctt
     4501 ctgtcacata aacatcaaga gctgtgctat cagtcacctc taaggcatta aagcggtcaa
     4561 tctgcttttg agaatgcttg gtatcccatg ccttaaagtg accctcctcg ctcacatagt
     4621 agctgatttc ttcagtctta gtccctacac ggattccctt gttatctcga tagtaaactg
     4681 tggaatcctt ataaccaaaa ctatactgtt ctaaactctc tctgatatca gctggaatcg
     4741 aggtatcaat gacttgtctt gccagtacgt ctgaattgat gaaaatgtca gaaggttcaa
     4801 caactctagg cgctttaacc tgtttaagag caatctgaac atctgcaatc aagttatcag
     4861 gattgccttt aacagaaagg gtgcctccat taaagtttct cacctcataa gttccaagaa
     4921 cttgaggatt gtactccccg tcaaagtaag gattcagcca aatacggtca tccttgtcat
     4981 aacgaatagc acctgaaaag gcaatgtcat aagcttgata atccttgtcc acatgtttct
     5041 ggaagaacaa catatccgtt gtgacattgg tacctgcaac ggccttaaaa gccgtatctg
     5101 gcaaacgcac accaccaaga aaatcagttg tttcgcgaat gtcctggagg atattttctg
     5161 tccgtttgtc catggttcca gtggaggaaa tgatagccac ttgaccacca tcatgcacca
     5221 aatcaagcga ttttttaaca aaataatcat gaatcatata gggcttatca taacgactat
     5281 cggcaatcct gatattggca aacggcacat ttgagatgac caaatcaaag ctattctcat
     5341 taaaggcaac ggtctcaaag cccttcactt caatgtgact atttggatgg aggtgcttgg
     5401 caatagctcc tgtaatcgtg tctaattcca caccatacaa ctcactattt tctctcaggt
     5461 gtttaggcat agccgcaaag aagtttcctg tgcccatcga agggtctagg attttacctc
     5521 ctgtaaagcc atcctgctcc aacttctccc acatctgacg gataagagca gggtctgtgt
     5581 aataggcagt caaagaggat tgtttcatgt ccgaatactc tttatctgtg actagcgttt
     5641 ttaatgcctc acgttcctta gaaaatttag gattatactc gtcaaagaac tcattagcaa
     5701 gccctcccca gcccacatat ttagcaagga gttcttgttc atcaggcgtg gcttgtcgtt
     5761 cttcagcttc aagagctttt acaagacgca tggcagccac gttcgtttca accttatctc
     5821 ttgttgtctt agggtaaaag tttgtcagat cttctgggaa gtgaaaatca gtggttggtg
     5881 tcatctcaat gacttcaaaa agctctgaat caatctcttc ttcaagagtt tcagattttt
     5941 ccacttcttt ttccatgact ggttcttgaa aaacgtcttc ttggttctca tcgtctagca
     6001 taaaggaaaa gaggtctaat tcttggctag gttgtttcac ttcttctttt tcctcggcag
     6061 aaggaagatg gagagcctga gtgatctcct ctaatgtccg taagaaaaga actggatttt
     6121 gttcaatcac atctgtaaaa tcattttgta gttcaatccg aatcaggtca ttgacacctg
     6181 actcttctat ggcaatcacc tttaagtcct cccccttata ggacaccgtg gaatcaatcg
     6241 gataacgttt aagggcttcc tctacaatag gattttgagg tgtttcttga ggcatgataa
     6301 tttcagattc tgtttgtgtt aggcgctctc gccagtctct aaaggatacg tctggctggg
     6361 actgtttgtc cctttcaaag gttctagctt cttcaatatc gaggtattca tgtaagaaag
     6421 cataggcaat cggtcttaag tcttctaact ttaactgact ggtcaagaag aactctgccc
     6481 tgtcatgcgt tagtcccatc tgaagcaatt ctgttgtaag agctaattga gtgacggatg
     6541 cgttaggata gccccctaat aaggctaagt ctgcattctt caaacggaaa cgccctgtgg
     6601 catctatcag taccccttgt ttattctcat caaagttagc taagtctatc cctaaactgg
     6661 tcagtttctc agtattctct gctaaaatcg tttgaccaat ttcagttaag atcacttctt
     6721 cttgcggtgt taggggacgt tgtaagtcgt aaatcgtccc atctgcttct aaatagatta
     6781 atagctcttc ttcctcatag ataggcatca tttccatctc atgatcaaac tctccacgtc
     6841 ttagatttgg cagttttgga cgactatttc tcacttggtc aaaatgactc aatatctcaa
     6901 acttctgaga caagtttaga tgttcatagg ctggtaaatg ttctgttttc cctgttcgca
     6961 aattgagttg cgagaggtct tcttcaagac tcgccatgat gacaaaactc tcttcacgaa
     7021 aggtaatttc tggactgggt tctacttcta tttcgtcact ctcggagata gtctcaatag
     7081 gtctggtatc cagctccggt tcataagtta agagaaattg ttcaatgtca cggctaatac
     7141 gatcagataa gttgttagcg actcggtaga cgttgaccaa gttagcagct ttgccttttt
     7201 ccaaaagaga agctaccgaa atagactgat aagctccctc ttggtctaat agctgaaagc
     7261 gagtagctag gttaaagagg gctacctcaa tcaccaaggc tttctcatcg ctgtttaact
     7321 gaggtaactt ctttaggcct gcttggccaa aggtccgcgt atagctactg aggtctgtcg
     7381 cttcgtcaaa agggctcgcc ttcacaaaag cagaaacttc tgtttcaaag cgaaccactt
     7441 gatcaggtga ggggactact cctctatggg ttgtaaaatc ttggataagg ctctcccaat
     7501 cttcatcaaa atgaactgct tgatagcgta aaaaggattc taaaagaatc tggtcacgtg
     7561 gcaatcttgc ccgcaacatc tcgagtaact gctcttgaat catacgttcc tccaaatcaa
     7621 aaaaggagct gagaggtagt ctcagcccac tgctttagtc taggactaag gtgctttggt
     7681 ctttttcttg tggcaactta tccactaaag tcgtcacata ctgttgtaag aaatggcttt
     7741 tctggtctaa caaatctttc tgcaaggcaa gataggtcac atctccaaaa taatcttgac
     7801 tagtgagagg caagtccttt tggataatat cttgcaaggt ttctaaggtg agcgatgaat
     7861 aatcgtcctc atccaaaacc tcatattgaa caagggtatc aaaaatatta ttagacgcta
     7921 tcacttccat aatgaaacta gctccctctc ctgttcgata gagtttatct aacaaatccg
     7981 tgagttcttc ttgaagctgt tcctgataac cgtctgctct taggcgcagg tcatcactga
     8041 ctaaagacaa gtcatcaatg cccataaagt cttgatagag cctgtcaaga agtgacttgc
     8101 ttttgatact caattccatg gttaataagg ctttgaccat atcttcatag ttttcttgtg
     8161 ccatctcaga gagagttttt gaaatcgtgt cataattcca agccataact gctctcctta
     8221 ccttgttgaa ttggattcaa gccttgttgg acttcttcaa ggtctgtcag tccatcacta
     8281 tccgtatcac tgctaaaaag attggtccct agagctaact cctgagcatc cgttaagcca
     8341 tcttggtctg aatccattgt gtaaatgctt ttaggttcca tttaattgtc ctccattttg
     8401 cgtttagcaa ggacataggc taagcctaaa agaagtcctc caccgacaag cgccaaaaga
     8461 gattgactct ctcctgtatt tggtaagaca cttgctggaa ctggtggttc ttgtgttgga
     8521 ataagtggtt ggggtggtgt tggttgattc ggagttggtg gctctggttc aggagtagtt
     8581 gttttaaccg tgtttgaact gatggtgtag ccattgacgg tatgtagtac cgtattttct
     8641 acttcacctg aagcgattcg ttttatctgc aagtaaacat ctgcctgaaa ctcggattct
     8701 tctgctagtt tttctaggaa ttccttgtca aaactgatgg taaccgttcc ttgtgacgtg
     8761 tcgacatgtt gtagcgtgta cttagtcact tctgtccctt ttagtaaaac cgtcccatct
     8821 tttagagtga catctaccac agtataagcc ttgtaaacac cattatagtc gtcatggctt
     8881 tcatcgtaat catcgtcaaa gcggtattcg atgagtggtg tcgcacgatt accaggaata
     8941 agtgctccca ccaagcggta gttaaagacc tgattcaagg caacttcttt tccatcaaga
     9001 ctgttctcct tttgtgacaa atcaatcacc acatcttttt gtgggtctag ttttggaaca
     9061 ttattgacca ctgtttctgt cacataagcc aaactaaagt caatctgata agccgtgttt
     9121 tcatacttgc caccagtctt tgtcaactca ttcttaatgg tcatcggaag cgtcaccacc
     9181 aaggtttgac ctgtcttaac ataggtctcg taaaaagctt ttggatcatc agcacttaaa
     9241 acttgaatgg ctccttttgg tgtaagttgg cgtttggcca tagcttcttg caccacttga
     9301 ggcgcttctg atatcgaagc ataggctttg acagaaatcc ctttgacaag atttcccgcc
     9361 ttatccatca cttgaacacc gtctgcattt agtgttagag cttcttctgg atagtcatct
     9421 accatgtaaa aacctttggc aagggtatcc tccgtcacta ccaagtcctt gtactgacta
     9481 taatccagaa caatcttata gtaatttacg gtattaggaa gaacggtttt gccatcaata
     9541 gacactccct ctttattggt attggtctta tgaggattta cctttggcac gtgattggtc
     9601 accgtattgg tttcataggc ttgcccaaag tctacttggt aagccacgtt atcataagac
     9661 ttccctgaat taagcatctc ctcacgaact gtcatcggtg taacgatggt aatgttttgg
     9721 cctttggtca cataagaatc ataaaaggct tgtggatctt ctgccataaa gacttggaaa
     9781 gctcctttag gcgcaatctt gcgtttctca aaggatgctt gtaggggttt aggggcttct
     9841 gataaactcg tgtagttttt taccgtaaca cctatgacag ccttgccgtt agatgtcgtt
     9901 agttgaatag ctgtgtcatc tggtagcaca gcttcttcag gatagtcatc cacaaagtag
     9961 aagccttttg cgatttgagc tttatcagct ttaatgccac ggtattggtc taaatcccat
    10021 gacaaggtat agtagttttg tgaacccact accatcggtt ttccattgat gtccacttta
    10081 tccttattaa ggttttgttt cttaggtgtg gggctgacaa gggtattggt cacctcattt
    10141 gttttatagc cattcccaaa atcaacttgg taggctttgt ttcgataagt cttagtttga
    10201 ccataaaggc tgtctttgac ggtcattttg gtgagaaggt tcaaagaggt tcctgtttta
    10261 acgtactggt catagaaagc ctgattgtcg ttaggctgga agattcggaa agctccttta
    10321 ggagaaatct tggcatgagc gagtttatct tgaaggtctt taggagcttc tgacagcgac
    10381 gcataggcct taacagtaat ccctgatacg gctttaccat caagagtggt gatacttgtt
    10441 cctttatcca ccaaatccaa gacttcttct gggtaatcat ccacaaagaa gaaaccacga
    10501 gcaatcgttt ctttagaaga ggtatcacct ttatattgat ctaaatccca cgtcaaacgg
    10561 taatggttag tcgttcctaa agccaccacc gtatcgttaa tgaccacacc gtcttcattc
    10621 tcattgcgtt tttgaggagt aatacggcta gtgattttcc catcaccagg tgtacgaacg
    10681 gtcaccacgt tagaggtcac tgtataggca tttgacgttc ccttattgat gaggagctta
    10741 taactattgg aataggtagc cccatcattt tgaaggctac cataaagttt aggagccacc
    10801 agttgataag acttagtgag gtcttgattg acctcttgaa gcaaggcttc tttggcagtc
    10861 agggtcacaa agttcttagc ttcatcaaag gtaagcgtat aattcccatt ttctgcttgt
    10921 gttttttctt tatcaaaggc atagcctgct ggaaggtaat cttcaaacgt aagggtagtt
    10981 gttttggcac gatttgaaga aaaaacgtca actgttaaag gataaataac tgtcgaatcc
    11041 ttggcgatag ttttgtcatg aagattgtct tggtcggtat tgaccacttt tttcatgatt
    11101 tcaggggtcg ttgtcagacg atagtcgtga taatgaaccg ttggtacttg tggtgcttta
    11161 ggcaaaggtt cagacctagg ttctttagca aaggtcacct ttgtcaaagt caagcgaggt
    11221 tgagtcactt tctccagtgg tttttcctta aagatcacag gtggctctgg ggtaaaggtc
    11281 tttggggtaa aagtttttgg cacgacttta atcggctctg ggactgggtc tagttttggg
    11341 ctcacatgtg gtttcggact ataaggtttg acggttcgtg caacaggtaa ggtgtttaag
    11401 gcaaaccaat aggtcagtcc tgcattctgg ggcatatcgc cttgtccaaa agtcacggtg
    11461 taggtattgc ctgatgtgac ggttgagaca atcgctccct tgtaagcata cttgctaaaa
    11521 gaggtatccc attcttctgg gaggttcaaa tcactagcac ggtttgaaga aagtgaacgt
    11581 gctaggcctt catctgtcac ttgaatggtt gagccattga tagggacaaa cttgcctgat
    11641 gtgtctttga catactctaa gccaatgtca ttatgattaa gtgaggaatg ggtaaagaca
    11701 cctggttttt ccttgctaaa gctgacttgc gagccatcct ctaagaaata cttggctttg
    11761 acacgaaact ccattttatc ggttcgccaa ttccctgtcc catcattacg ataggcaata
    11821 aagccttctg ttgggtcatt aggcacaact aattgtacag aatccgtctc agttggagac
    11881 actaggtttg tgatgtcata agcgactttg gtaatctttt taccatcaaa actcacattt
    11941 tgaaggtttt gataagtgaa tgaaagggtt tctccagttt taaaggtatc atagacgaag
    12001 aaaccagtag aatctaggat tttagaatac ccaccaagca tggcgtcacc cttagcaatg
    12061 atgcgattag gatttctcgt gtcagctgaa tgtcgggctt gcggttcccc attgttcaag
    12121 ttgagagcct gagcaagagc ttgtgagatg taaccttcct ctccttttga gatgtcagct
    12181 aagtcacgtt tgtatcggtt catttctttg gcattgtagg catcaatggc ttcattttct
    12241 ttcttagcag cttcttcttt ctccttattg cgttttataa tagcagcaat ctcagcttca
    12301 cggtctgtca ccaatttttg ttggttctta ttgtaggtat ccacagcagc ttgacctgct
    12361 ttattttcat catcaatcgc tttttgttct gcttgattgc gtttagtaat cgcttcattc
    12421 tctgcctttg cattcgcaag acctgcttca ttttcctttt gaacagctag gttctttgcg
    12481 gtaatggcat ctgcggcttg ttttttcgtg atatagtccg caagactagc cttgttttgt
    12541 ttatcaatag cagctaccgc agatgtgtag tcctgataac ctgaaacagt tgatccctct
    12601 cctgacggaa cggtttgagt tgtaatagtc acgttcgcag acttgtcctg agtctgcact
    12661 tctgaagccg tggtatctac tgaactattc aaggcctttc ctgcttgagt agcttcttta
    12721 tgactagcaa ccaacgcagc attccctttt tcgacacgag ttttatcttg ttcataagcg
    12781 gctttgtcag ctttataggt atttgtcacc cgagtgatgt cctcagcttg tttggcagca
    12841 tccgcttccg ctttatctaa ttgcttactg gtatcactcg cagaggttgt gtttcctaaa
    12901 tccatcggct ggtcttgaac agtagttacc ccttcagcag ttgcttgatt gatggcattg
    12961 gttaccgtat catgaggaac cgttactgtg atagtcccat ctgattgacc ggttgacgca
    13021 aggctatcag tctgttcagc aactggtgct ggctgagctt ctggtaaatt ggtcgcatta
    13081 ttttccgtta actgaacagt cttatctagt ggtggcattg tcacttcgtc agcctgggct
    13141 acttgcccac cccaagcgac aacagctgtc accatagttc caagtgctac cgaacacagc
    13201 gtacggtact tcttactttt acggaagaca tgcttttctg cttgttcctg attgactaaa
    13261 aagtgatgat gacattgttt ggtcataaaa agtccttctt ttcttttgat aagtagcaac
    13321 aatctgtcac tctctcctca tcataaaaaa gacgacttga ttttggtatc acatcacata
    13381 agagactagt aaatgctaat taataacacc caaaatgttg cttctgcacc gttaaaatgc
    13441 taaaattaaa gtacaaaagc aacaaagaaa ggagagatta tgtctaaaaa agaattgtta
    13501 cttgagtaca taaacaatca caatggtctg attacccata gagattgtaa aaaattaggt
    13561 attccaacca tctatctaac gagactagaa gacgaaggag ttatctttag ggtcgaaaaa
    13621 ggtatctatc tatcttctag tggagattat gatgaatact atttcttcca atatcgttat
    13681 cctagaactg tcttttctta tatctcttct ctttatctac agggacttac tgatgaaatt
    13741 cctcaatatt ttgaagtaac agttcccaag gactatcgtt ttagaaacag accattgaat
    13801 ctaaatagct acactgtttc taaagatatt attaacatgg gggttaccag tgtcaaaaca
    13861 cctatgggaa atacggttaa cgtttataat tttgaacgtg tactatgcga ttttatcctt
    13921 aatcgaagta acattgataa tgagctcttt gttaaaacag ttcaaactta tagtaacttc
    13981 cctgaaaaaa atcttgcaaa actttatgac tatgctcaaa aattaaatat cttagatgat
    14041 gttaaacgaa ccttggaggt actcttatga ataaagcaaa attaacagca ctctgccata
    14101 acatttctaa acagaccggc ctaactttta actcagtaat gacctactac tttcttgaag
    14161 tcattttgaa aaagctaagt cgaagttctt atgcagacca ttatattttt aagggaggat
    14221 ttttgctttc aaatatcata ggagttgaat ctcgtagcac ggtggatatt gattttctct
    14281 ttcataaaca aacactatca gaagaaaatg ttcaacaaca actggaagaa attttaagtg
    14341 aagtaaaaaa cgatattcaa ttttcaattc aatccattac aacgattaaa gaaagcgatg
    14401 attacggtgg ttaccgagca accattttgt gtcaactgga aaacattaaa caaattatcc
    14461 atttagatat tgcgactgga gatgttgtta cacctcagcc cattacctac gattacaaag
    14521 ctatttttaa tgatgagaat ttccccatca ttgcttatac aattgaaacg gtgctagctg
    14581 aaaaattaca aaccatttac tcaaggagct tcttaaacag tcgtagcaaa gatttttacg
    14641 atatctatat cctttcaaag ttaaagaaag acgacattga tttggcacaa ttaaagatgg
    14701 cttgtgaaaa aaccttctct tatcgtgaaa ctgaactcaa ttttaataac atcattcaac
    14761 tgcttgaaac cttcaaatct gactctactc agcagcaaca atggcaaaat tattcaaaaa
    14821 aatatagtta tacaaaaggg atttcctttt cagaaatcct tgatgagatg attcgtttag
    14881 tcagtctttt aatctcttta aacaatgaat aaaacaactt ttcggttatc ttttaaccga
    14941 tacagacaac attaaaagga tatgcgagca actccttacc ttgttcgcat atcctttttc
    15001 ttatttcatc gtatacgcaa aactaatcgt accatctact cctgataact tacggaaggt
    15061 gtaattggga ttaccattgt agttggtctc tgagatgagg aacgatccat ctgggtaaac
    15121 ct
//
LOCUS       DAVDZK010000046        14297 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVDZK010000046 DAVDZK010000000
VERSION     DAVDZK010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.047"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..147
                     /locus_tag="VUX16_001825"
     CDS             <1..147
                     /locus_tag="VUX16_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET8124733.1"
                     /translation="AKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFV
                     LSRY"
     gene            complement(212..284)
                     /locus_tag="VUX16_001826"
     tRNA            complement(212..284)
                     /locus_tag="VUX16_001826"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(249..251),aa:Lys,seq:ctt)
     gene            complement(549..1820)
                     /locus_tag="VUX16_001827"
     CDS             complement(549..1820)
                     /locus_tag="VUX16_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET8124734.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            2118..2333
                     /locus_tag="VUX16_001828"
     CDS             2118..2333
                     /locus_tag="VUX16_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124735.1"
                     /translation="MMELPSQEILIFTKQIRHWILSDQVISGKRKLFFREDIPKEILD
                     LYENIKSKLDFAYQEVYSNNGLKKYEK"
     gene            2323..2571
                     /locus_tag="VUX16_001829"
     CDS             2323..2571
                     /locus_tag="VUX16_001829"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124736.1"
                     /translation="MKNRIIDVFEVVNRILVITVENPDFEDLRVNQFVKIGDKKYRVR
                     SGPMIHSTPPQSVLDRDTFTIDYTDDELLDKEAVFTTH"
     gene            2708..2887
                     /locus_tag="VUX16_001830"
     CDS             2708..2887
                     /locus_tag="VUX16_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET8124737.1"
                     /translation="MPMTQKEMVKLLTAHGWIKIRGGKGSHIKMEKQGERPITIPHGE
                     LNKYTERGIRKQAGL"
     gene            2924..3376
                     /locus_tag="VUX16_001831"
     CDS             2924..3376
                     /locus_tag="VUX16_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET8124738.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQT"
     gene            3667..4137
                     /locus_tag="VUX16_001832"
     CDS             3667..4137
                     /locus_tag="VUX16_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET8124739.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            4156..5223
                     /locus_tag="VUX16_001833"
     CDS             4156..5223
                     /locus_tag="VUX16_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET8124740.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVGITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENWLAELEKELAEGV"
     gene            5225..5653
                     /locus_tag="VUX16_001834"
     CDS             5225..5653
                     /locus_tag="VUX16_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET8124741.1"
                     /translation="MEIEISDFTGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECAAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            5788..6741
                     /locus_tag="VUX16_001835"
     CDS             5788..6741
                     /locus_tag="VUX16_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET8124742.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPETVDVAAVEADLQARLAELTDFMDLGEVKMGTTAL
                     AEEDWADNWKKYYAPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SLFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNT
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRESAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            6743..7486
                     /locus_tag="VUX16_001836"
     CDS             6743..7486
                     /locus_tag="VUX16_001836"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET8124743.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            7498..9294
                     /gene="pepF"
                     /locus_tag="VUX16_001837"
     CDS             7498..9294
                     /gene="pepF"
                     /locus_tag="VUX16_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET8124744.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALANLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAQYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(9354..10031)
                     /locus_tag="VUX16_001838"
     CDS             complement(9354..10031)
                     /locus_tag="VUX16_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8124745.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEQGKEF
                     LEKEWGI"
     gene            10299..11411
                     /locus_tag="VUX16_001839"
     CDS             10299..11411
                     /locus_tag="VUX16_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HET8124746.1"
                     /translation="MNLPKIKDIHSVLFLKDKIRLGIGKDYGIEIENLDEKYTQLIKL
                     LDGQYTINEICSLVDSLSPNEVEESISLLDTLGYLEDNFVTTTELTSEELDRYSVNLN
                     FFNTLDTLSLTKYDYQLKLKKTRILLLGIGGIGSNICLALAELGIGHITAVDFDTVEA
                     SNLNRQILYSTSDIGKRKVEAAKESLRKFNPLIEFEVLDKEIGSKEDVDELIKTSKCD
                     IVVNVADYPTGYIDFWVNEACVQYNKLCLSAVVGKKNGKVYSIIPYKAACYYCQFLED
                     LEKIPEYAEELETVRTMTNSLELEMFRTPNGALGPACLFQGYFISFEILRYIFWGYEA
                     LLTFNKRFSIDFITFEQHFDELTKYPTCSICGGKKE"
     gene            11381..12067
                     /locus_tag="VUX16_001840"
     CDS             11381..12067
                     /locus_tag="VUX16_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124747.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GKNIETNRRKSKSCLGIVGQEDMLDMTLNVYDNLFAHGLCYGISSVELRKRIGSLLDF
                     VQLSKHAQKMVNQLSGGMRRRLVLARALINRPDIIILDEPTVGLDIQSRNIIWDKLLE
                     LKELGVSIIITSHYMNEIEYLTDRVLMLHQGTIKEEGTVEDLLIKYDADNLETLFLGL
                     TGTEKEDLHV"
     gene            12060..12824
                     /locus_tag="VUX16_001841"
     CDS             12060..12824
                     /locus_tag="VUX16_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124748.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIAPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWSGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            13249..14040
                     /locus_tag="VUX16_001842"
     CDS             13249..14040
                     /locus_tag="VUX16_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET8124749.1"
                     /translation="MYQKLLRKIAEEKPSYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFYFIAEGISSDGGLDKDIDKVGLSTLERSFRALIYVNLLSADANQ
                     QSIFYQRLKSEIRNVLLNQGLYYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPN
                     FPKTRVHEVFDILGQLFKRITIRFTDDEDWRLARVLYEPILQGKLEQEQVASWIKIVD
                     FPIEEREDFYKFSNFRSCLSEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            complement(14105..14297)
                     /locus_tag="VUX16_001843"
                     /pseudo
     CDS             complement(14105..14297)
                     /locus_tag="VUX16_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
BASE COUNT         4205 a         2480 c         3265 g         4347 t
ORIGIN      
        1 gccaaactgg aagcgaccaa taatctcatc aaacttatca agcgcaatgc ctttggtttt
       61 cggaactttg aaaacttcaa aaaacggatt ttcatcgctc tgaacatcaa aaaagaaagg
      121 acgaaatttg tcctttctag atattagctg acttcaaccc actacagttg acaaagagcc
      181 tgaaaccaag gcttttcttg ttgtatgtag atgcccccta cagggatcga acctgtgacc
      241 cacggattaa gagtccgctg ctctgccagc tgagctaagg aggcaaagaa aaaagctgta
      301 ttggtgccga aacttcacgg tttgtattga acccgcgcaa ttaagcaggt gggcaactcg
      361 ctctaactga agctgtttcc gtgtgagacg gcctacatgc tgttagaaga cttttgtttc
      421 cctaataata caaaaaatag tcggtcaaca cttaagtgtg aagtcgtaca ccacagcgtt
      481 tctatattta tatgatacca ctttttcaaa aaaaatcaag aggaaagtgc aattttttga
      541 aaaggatttc agatttttcg caaacggtcg atagcttcct ttctttgagc caaagcccgt
      601 tcatatttac cagtatcttc tgcttggaaa tagtgatgat tacgaatttt ttctggcaga
      661 tagtcttgct tgacccaatt tccaggatag ttgtgtggat agagatagtc ttgggcattc
      721 cccagttcct tgcttccact gtagtgccca tcacgcaggt gtcgcggaat aggcaagtgc
      781 cctgatgttt tgagatcagc aagtgcctta tccatagcta cataggctga gttggatttt
      841 ggagaaaggg ccaaatcaat cacgacattg gcaatgagaa tgcgggcttc tgggaaccca
      901 atcttctgtg cagcatccag agcagtcacg gtatgaatct gggcctcagg attggctaag
      961 ccgatatctt cataggcgat aacagtcaag cgacgagcga gactaggcag atccccagcc
     1021 tcaatcaagc gggcagcata gtggagactg gcatccacat ctgagccacg gatagacttt
     1081 tgcagggcag atagaacatc atagtgaccg tctccatcct tgtccatagt gatgtagctt
     1141 ctctgaagac tattttccat gatgtctaag gtgatgtggc gaatgccctc gtcattctca
     1201 ggggtagaga gaacagccaa gtccagtgag ttaaaggcag agcgaaggtc tccgtttgta
     1261 gaggttgcga tgaaatccag cgcatcctca tctagttcta ttggaaaatc aaaaccacgt
     1321 tcagggttac ttagagctat ctgcagggcc tctttgacgt cttggttaga cagaggttcc
     1381 aactcaaaaa tttgaacacg gctacgaatg gcaggagtga cggaaaagaa aggattttca
     1441 gtcgttgctc caatcatgat gaccagtcca ctttccaaga gaggcaagag gaagtcttgc
     1501 ttggtcttat ctagtcgatg aatttcgtct agcaatagga cgagaccacc agaaaattta
     1561 gcttcttccg agatttcttg cagtcgcttt ttactatcaa ctgtcgcatt gaaagttcga
     1621 aaggcatact tggtcgttcc agcgatggca gaggcaatac tggttttgcc gattcccgga
     1681 gggccataga gaatcatgga ggacaggcgg ttggcttcca ccatgcggcg gatgattttt
     1741 ccaggtccga ccagatgctc ctgaccgatg acctggtcga tggttttagg gcgcatacga
     1801 agcgcgagat tgtctggcat agcagtcctt tctaacgtgg atttgagtag aatgactcat
     1861 ctactatatc ttactatgtc cattctagcc tattagttgt gatatttcaa tggttttgta
     1921 ataatcaggg agtgagatag aatctttttt actatttaat ttaataagga gaggtatcag
     1981 catgagagat ttgattttcc ttaaagctca aaataggata gttgagccta aagaagtgga
     2041 agtgctgact tgagaaataa tattgctaaa tgtcattgta tgaactataa tgaaaagaga
     2101 ggtgataagc aatggaaatg atggaactac caagtcagga aattttgatt tttacaaaac
     2161 aaattcgtca ttggattctt agtgatcaag ttatttcagg gaaaagaaaa cttttcttcc
     2221 gggaagatat tccaaaagag attttagatt tgtacgaaaa cattaaatct aaacttgatt
     2281 ttgcttacca agaagtttat tctaataatg ggttgaaaaa atatgaaaaa tagaataatt
     2341 gatgtttttg aagtagtaaa tcgcatcctt gtaataactg ttgaaaatcc tgatttcgaa
     2401 gacttgagag ttaatcagtt tgtaaaaatt ggagataaaa agtatagagt acgcagtggt
     2461 cctatgattc attcaactcc gcctcaatct gtcttagatc gagatacttt tacaattgac
     2521 tatacagatg atgaattgct cgataaagaa gcagttttta ctactcatta gaaaaatagg
     2581 tatgaataaa ttggcttccc ttagaaccac atctaggggc ttttatgtat aatagaataa
     2641 taagtatcac tcctttacaa tacgtgtaac acgtgttata atggtgttgt caggaggtaa
     2701 aagcgctatg cctatgacac aaaaagagat ggttaaactc cttacggccc atggttggat
     2761 aaagattaga ggcggtaaag gttcccatat taaaatggaa aagcaagggg aaagacctat
     2821 cacaatccct catggtgagc tgaataagta cactgaaaga gggataagaa agcaagctgg
     2881 gttgtaaaat tcagcccctg ctttttgata tggaggtagt gaaatgttag ttacgtatcc
     2941 agctttattt tattatgacg acacagacgg aacagaagcg acttattttg tccatttccc
     3001 agattttgaa tactcagcta cacaaggaga ggggatttct gaggctttgg ctatggggtc
     3061 ggagtggcta gggataactg ttgcagattt gatagagagt gatggagagt tacctcagcc
     3121 atcagatatc aatagcttgt ctttaattga taatgatcct tttaaagatg atgaagattt
     3181 cgtgtcaacc tatgaccttg ataaatcttt tatttctatg gtatctgttg atgtatcaga
     3241 atacctagga agtcaggaac ccattaaaaa gactttaacc ataccaaaat gggcagataa
     3301 gttgggacga gaaatgggac ttaacttttc tcagactttg acagacgcta ttgcagataa
     3361 gaaagttcaa acctaagatt aagcgtggta tcgtggtaat agtcaataaa aaagcacgtc
     3421 cacttgtgct agttactcgc ctattgattt tatagattta ttagcccttt cgagggcttt
     3481 ttatattgat ttttatgaga aatgaagaaa tcagactttt aagaaaatca ctgataccaa
     3541 gggtttaaat gaggtaatat ggtataatta ggacataaaa taattttgtg gtaagatggt
     3601 agtatctatt ctagcatatt tccgagcaat cggggcgatt aaagagtcgc atagaaagag
     3661 gacaaaatgg caacatacgg atttttagat gttttagagg aagagttgga caagaacttt
     3721 ccctttgact ttgagattag ctgggacaaa cgcaaccatg cggtagaagt gagttttcta
     3781 ttggaagcgc aaaatgctgc aggtgtggag atggtggatg aagacggaga ggtttcatca
     3841 gatgacattc tttttgagga agcggtcctt ttctacaatc ctgccaagtc aacagtcaat
     3901 gaggaagact atttgactgt tattccttac ctgcctaaaa aaggattttc ccgtgaattt
     3961 ttagcttatt ttgcgctttt ccttaaagat actgctgagg ttgggctaga tgtcctcatg
     4021 gactttttgg aagacccaga agcagaggaa tttatcatgg aatggaacca agaagtcttt
     4081 gaagaaggaa aagttggctt ggaagaggga gaattttatc cttatccaag atactaggag
     4141 ttggttggag gtgttatgaa gaaaattggg acttatttgg tttatgtgct agcttttgtc
     4201 tttattatgc tagcttttgc ttgtggaaca atcgcatttg cagagttggg gtattccgca
     4261 gttttagcct ttacttttgg ttatgccttc gctcttctaa gcatgtattt aatctttatt
     4321 cttcatgagc tgggtcatgc tttttgtggc tacttgacag gctatcggct ggtggctttt
     4381 ggattaggac attttatttt gaccaaaaag tcaggcaggt ttcatcttag tagaacagcc
     4441 attctgaaaa atgttggtgc tcaatacatt ggtttaaaag aggatgaaag cgatcaaaga
     4501 atcatcctga tgctttcagg aggcttgatg gttcatctcg gcttgatatt attggcgata
     4561 gtgtttggat ttttgacaag aagctggtat tttgcaggga cttggatttt tcttaattta
     4621 tctttcttcc taaataacat tttaccagtc ggcatcaccg atggagcaaa aatttgggaa
     4681 ttactacaac accctgaaaa taccaaatac gcctacctgg tattgagaca ttctgctcaa
     4741 actttgctgg ctcctcaaga atatgatttg aaagactttg ttcaagcagt tcctgaggat
     4801 gcacgaggga gttttgcgga tggtgtatta ggtatgcaag gtgaagtttc cattttggaa
     4861 gggaaggaag aagtagctaa acagcagttt caagcattac ttgagaggac aactactccg
     4921 atgatgcaga cagttgccca actatccctg cttcatatcg ctttgttgga aggagatttt
     4981 gagcaagcgg agcaatatgc tagtattcga caggtcaaat cgtttctgtc tctcaaactg
     5041 tccaatcttc aagtgataca agcctggtat caattaaagg tgaagaaaga tgtagatcga
     5101 actcgtaagg ctctcaagat tgctagacag aaaatggata gtagtcgaat gttgagggat
     5161 gagaaaagat attatgaaaa ctggttagcc gagctggaaa aggaattagc cgaaggagtc
     5221 taatatggaa atagagattt ctgatttcac aggttgcaag attgctttgt tttgtgggga
     5281 taagcttttg actatcttac gcgatgataa ggcaagcatt ccctgggcca atatgtggga
     5341 actgccaggt ggtggacgtg aaggtgatga aagtcctttt gagtgcgcag cgcgtgaagt
     5401 ttatgaagaa ctgggcattc atctgactga agattgtctg ctttggagta aggtttaccc
     5461 aagtatgctt tttgcagata aacagtccgt ttttctagtt ggtcagttga cacagaacca
     5521 gtttgacagt atcgtatttg gagatgaagg acagggctat cagctgatga atgttgagga
     5581 atttcttagt tccagtcaag ttgtgcctca gttgcaagag agattaaaag attatttaaa
     5641 agtaagtgat tagaaaggat ggttcagtta aatttctaaa ctgaacccgc cctaaacact
     5701 gtgccaaaaa gataaacttc tcttagacac aagcgtcttc agagaatttc ctattttggt
     5761 tttgtgtttt acgggcttgg tatcttaatg atggaaacat ggcaagagtt aaaagttaca
     5821 gtgaagcgtg agggggagga attggtttcc aatctcttga ttgagctggg agcgcaagga
     5881 gtcgcaatcg aagacagtat ggactatgtg ggaaatgtgg accgcttcgg cgagattttc
     5941 ccagaggtgg agcagcaaga agaaatcgta gtgacagcct actaccctga aacggttgat
     6001 gtagcagcag ttgaagcgga tttgcaggct cgtctggcag aattgaccga ctttatggac
     6061 ctaggagaag tcaagatggg cacgactgcc ttggctgagg aagactgggc tgacaactgg
     6121 aagaagtatt atgcaccggc acgcatcacc catgacctga ccatcgtacc gtcatggacg
     6181 gactatgagg caacagcagg agaaaagatt atcaagctgg atcctggtat ggcctttggg
     6241 acagggaccc acccaacaac caagatgagc ctctttgcct tggaacaggt tcttcgtggt
     6301 ggcgaaacag tgctagatgt agggactggt tcaggggttc tttctattgc aagctcactc
     6361 ctaggtgcca aggagatttt cgcctatgac ttggatgatg tggcggttcg tgtcgctcag
     6421 gaaaatattg agctcaacac tggtatggaa aatatccatg tagcagcagg agacttgctt
     6481 aagggagttg agattgaagc agatgtcatc gtggctaata tcttggcgga tattctcatt
     6541 catctgacgg aggatgctta tcgcttggta aaggatgaag gctacctcat catgagtggc
     6601 attatcaagg ataagtggga catggtgcgc gagtcggctg aatcagctgg atttttcctc
     6661 gaaactcaca tggttcaagg ggaatggaat acctgtgtct ttaagaaaac caaggatatc
     6721 tctggtgtga ttggaggcta gcatgcagca gtattttgta aaaggcagtg ctatttctcc
     6781 tgtcactatc gaggacaagg aaaccagtaa gcatatgttt caggttatgc gcttgaaaga
     6841 agaggatgag gttaccttag tctttgatga tggcatcaag cgcttggcgc gcgtgctgga
     6901 tatggaaaat cgtcagtttg agttggtcca agaattaaat gacaatgtgg aactaccagt
     6961 ccaagtgacc atcgcatctg gatttcccaa gggagacaag ctggagttca tcgctcaaaa
     7021 agtaaccgaa ctgggtgcta gccaaatctg ggcctttcct gcagactggt cagttgccaa
     7081 gtgggatggc aagaaattgg gtaaaaaagt tgaaaaacta gaaaaaattg cccttggagc
     7141 agccgagcaa agcaagcgta atattgtacc aagtattaaa cttttcgaga aaaaagcaga
     7201 ttttctagct cagctggacc agtttgactc tatcatagta gcctatgaag aatcagctaa
     7261 agaaggagaa gccgctgcgc ttctgcaagc agtcactggt cttgaaacag gagccaaact
     7321 gctctttatc tttggtccag aaggtggtct gtcacctgcg gaaattgaaa attttgaagc
     7381 taagggagct gttttggcag gacttggccc tcgcattcta agagcagaaa cagcaccgct
     7441 ttacgcttta tcagccctta gtgttttagt agaattagag aaataaagag gaagaaaatg
     7501 gaacaaaaac accgttcaga atttccagag aaggaactct gggacttaac agccctatac
     7561 caagaccgtg aggatttctt gcgtgcaatc gagaaagctc gcgaagacat caaccagttt
     7621 agccgtgatt acaagggcaa tcttcacact tttgaggatt tcgagaaggc ctttgcggaa
     7681 ttggaacaga tctacattca gatgagccat attggcaact atggttttat gcctcagacg
     7741 acggactata gcaatgacga atttgccaat attgcccaag ctgggatgga atttgaaaca
     7801 gatgccagcg tagccttgac cttctttgac gatgccttgg tggtagcaga cgaggaagtc
     7861 ttggaccgtt tgggtgaatt gcctcacttg acggcagcta ttcgtcaggc caaaatcaaa
     7921 aaagcccact atctaggggc tgatgtggag aaggccttag ccaatctcgg tgaagttttc
     7981 tatagtccgc aggacattta tactaagatg cgagctgggg attttgaaat ggctgacttt
     8041 gaagcccatg gcaagaccta caaaaacagc tttgtcacct atgagaattt ctaccaaaat
     8101 cacgaggatg ctgaggttcg tgagaaatcc ttccgttcct tctcagaggg acttcgtaag
     8161 caccaaaata cggctgcagc agcctatctg gctcaggtca agtctgaaaa actcttggct
     8221 gatatgaagg gatacgactc tgtctttgat tatcttctag ctgaacaaga agtggaccgt
     8281 gtcatgtttg atcgccagat tgacctcatc atgaaggact ttgcaccagt cgctcagaga
     8341 tacctcaagc atgttgccaa ggtaaatggt cttgaaaaga tgacctttgc agactggaaa
     8401 ttggacttgg acagcgccct gaatcctgaa gtgactattg acgatgccta tgatttggtc
     8461 atgaagtcgg tagaaccttt ggggcaagaa tattgtcagg aagttgctcg ttaccaagaa
     8521 gagcgctggg tggactttgc tgctaacagt ggcaaggatt ccggtggtta tgcggcggac
     8581 ccatatcgcg tacaccctta tgtcctcatg agctggacag gccgtttgag cgatgtctat
     8641 accttgattc atgaaatcgg gcattctggt caattcatct tttcagacaa tcaccaaagc
     8701 tatttcaacg cccacatgtc gacctattat gttgaagcac cgtcgacctt caatgaattg
     8761 ctactcagtg attacttaga gaaccagtct aatgacccac gtcaaaaacg cttcgctctg
     8821 gctcatcgct tgacagacac ctacttccat aactttatca cccacctctt ggaagcagcc
     8881 ttccagcgta aggtgtatac attgattgaa gaaggagaaa ccttcggagc aagcaaactc
     8941 aacagcatta tgaaggaagt tttgacagat ttttggggcg atgccattga aatcgacgac
     9001 gatgcagctt tgacttggat gcgccaagct caatactata tgggcttgta tagttacact
     9061 tactcagcag gactagttat ctcgactgct ggttaccttc atcttaaaaa ctcagaaact
     9121 ggagctgaag actggctcaa tctccttaaa tcaggtggta gcaagacacc acttgagtca
     9181 gccatgatta tcggtgctga tatttcaaca gacaaaccac tccgtgatac catccaattc
     9241 ttgtctgaca cagttgacca gattatcgcc tacagtgctg agttggggga gtaaggggat
     9301 agagaggttg ttatagaatg ggtatggaca gttatttgct taaaattcca tgtttaaatc
     9361 ccccattcct tttcgaggaa ttctttgccc tgctctgtaa tggtaagtga acgtggcgtt
     9421 tgtgcaggga tgaccaattg tttttcactg aaaaattcta aaagagcatt gccgagagct
     9481 ccgccgacat gatttttacg ttcgctccaa tccaaacatt tagggcaaaa tttccgtttt
     9541 ttctttttca attcatccgt atcaatgtgt aattttcttt ggaaataaga cttcccagct
     9601 tcagtgagtt ggaagtcttt ttctgattcg ctgaggagat tttcttgcaa gagataattg
     9661 gtaatggaaa tgccaagctc accagcaata tggtcatagc aggtgcgagc gacttttaat
     9721 tcctttttgt gaatgtgttg tttataactt ttgacatcac gctgaggaga gtagaagctg
     9781 agaaattcca gcatttctgc aatggcagca ctttttaaag aataataatg aaaacgtcca
     9841 taggtttgta gagtggttac ctgcgcttcg gtaagtaatt tgaggtgata gctgacagta
     9901 tgttgcttga ttttggtaaa gctggcaatt tcgttaaccg tgtgagcttt tccatccatt
     9961 agaatatcta aaatgtgcat ccgagaaggg tctgataaga gttttgtgat gatgaaaata
    10021 tctggttcca taaaaatttt ctccaaattt catatatcga tgattttcta tcttttatta
    10081 tactataatt aaagcacaag aaaaatagat tttaaaaatg ttttactaga gaatatttta
    10141 aattttattg tctgagttta aatggaggta aaattacaaa agtaattgca gcagtatcca
    10201 cagttgaagg acgttaatct taagattaca ttctcaacat tttttcaaaa gtgaatggat
    10261 ttttccattc tttttgtcta ttttaggagg aaatagaatt gaatttacct aaaattaaag
    10321 atattcatag tgtcctattt ttaaaggata aaattagatt aggtatagga aaagattatg
    10381 gtattgagat tgagaatctg gatgagaagt atactcagct cattaagctt ctcgatggac
    10441 aatacacaat caatgaaatt tgtagcttag ttgatagctt gtcccctaat gaggtagaag
    10501 aaagtatttc tttactagat acactagggt atttggagga taattttgtt actacaactg
    10561 aattaacttc agaagaattg gatagatatt ccgtaaatct taactttttt aatactttag
    10621 atacattatc tttaacaaag tatgattatc agttaaaatt aaaaaagacg cgtattttgc
    10681 tcttaggtat tggtggtata ggaagtaata tctgtctagc attggctgaa ttaggtatag
    10741 ggcatattac agcagttgat tttgatacgg tcgaagctag taatctcaat agacaaattt
    10801 tgtattcgac atctgatatt ggaaaaagaa aagtagaggc tgcaaaagag tcgcttagaa
    10861 agtttaatcc tttaattgaa tttgaggtac ttgataaaga gataggttca aaagaggatg
    10921 tcgatgagtt aataaaaact tcaaaatgtg atatcgtagt aaatgttgca gattatccaa
    10981 caggctatat tgatttttgg gtcaatgaag cctgtgttca atacaataaa ttatgtctgt
    11041 ctgctgtggt tggtaagaaa aatgggaaag tatattcaat tattccgtat aaagcagcgt
    11101 gctattactg tcagttttta gaggatttgg aaaaaattcc tgagtatgct gaagagttgg
    11161 agaccgttcg tacaatgaca aattcattgg aactagagat gttcagaact ccgaatggtg
    11221 ctttaggtcc tgcttgtcta tttcaagggt attttatttc gtttgaaatt ttaagatata
    11281 ttttttgggg atacgaagca ttgctaacat ttaataaaag attctcaatt gactttataa
    11341 cattcgaaca acattttgat gaattaacaa agtatccaac atgctctatt tgtgggggaa
    11401 agaaagagtg aagaagttaa gtgttaaaaa tctaaaaaag caatatggtt cttatgaagc
    11461 tgtcaaggga attagctttg aattgggaga aggagagtgt ttgggtatct tggggaaaaa
    11521 tattgaaacc aatcgtcgta agagtaaatc ttgtctgggt attgtagggc aggaggatat
    11581 gctggacatg accttgaatg tttatgataa tctttttgct cacggtctat gttatggtat
    11641 ctcatctgtc gaacttagga agagaatcgg ttctctcttg gattttgttc aactgagcaa
    11701 acatgcgcaa aagatggtga atcagctgtc gggtgggatg cgacgacgtc ttgtcttggc
    11761 aagagctctc atcaatcggc ctgatattat tattttagat gaaccgacag ttggtttaga
    11821 cattcaatcc cgcaatatta tttgggataa acttttggag ttgaaggaat taggtgtttc
    11881 catcattatt acttcccact atatgaatga gattgaatat ttgacagata gggtgctgat
    11941 gctccaccaa gggactatca aagaagaagg aactgtagaa gacttgctca tcaagtatga
    12001 tgctgacaac cttgagacac tttttttggg gttgactggg acagagaagg aggacttgca
    12061 tgtttaagtt atcatttcac tccatcggac acgttgtggt acgcaactac atgagtttta
    12121 gaaatttatt taaaatttca attgtcccca accttatcgc ccccctcttt tatcttttag
    12181 caatgggatt tggagttggt gcttatttga cgcatgttaa cggtatgctc taccgtgatt
    12241 ttgtcattac aggtttaatt gctgcgactg ccatgtctgc ggccaccgca gaaacaacgg
    12301 tcaatgcctt tatccagtat aagattgaaa agacttatga tgctatgttg atgacgccaa
    12361 tcaatacgaa tgatattgtg gtgggtcagg ctatctggtc aggtattcgt gcagtgattt
    12421 tcggtgggat tttttggctg atttccatgc ttatcacagc gcattttcat gtcttgatgt
    12481 tattgattcc tctgatttta tttatagtgg gttatttgtt tggtgttttg ggactaatct
    12541 ttacctactt ggcgccgtct agggaatttc tgaattacta caatgttttg gtaatccgtc
    12601 ctctttatat gttttcagat accttctttc ccattacttc cttgccccca atacttggtg
    12661 atttgacttg gttttctccc ttgtatcacg ctacccgcat gattcgtatt atatggggag
    12721 gtgaggtgac aggtttgtat cttcatctta tctggttgat agccttggcg ctcttgataa
    12781 cggtgcttcc tatgtatatg ttacatcgta gatattatag atagtctaat tatttgtgat
    12841 gttgtagtca tattctaatt tatactaaac gttattcgaa tttggatagg tatgggaact
    12901 gtgcctatca atattgtaat ttatggaagt tgaaatagta cggttcagtt tttaaaatat
    12961 tgttagaaat tgttttaaat tccctaatca atttgtatag tttttatttc actttattat
    13021 aactagtttt tcgcaatttt tgagacagga atgtgatttt tgtgataaag ttctatcatt
    13081 acaagttcat ttgtggtaat atggaataaa tcatttatgt atcctttcag aaatgtgctg
    13141 tttctctgaa tataaatgtc tttttctctt taacttaatt ttacaaattg ctaaagtcat
    13201 ttaaggacag ctttttgaac agttgctaga aatgtagagg tattgaccat gtatcaaaag
    13261 ttacttagaa aaatagcaga agaaaaacca agttataacc aggaagaaat ccagtggcta
    13321 cttgatcatt tgggagatcc ttctccagaa attcgtgatg accttgtttt tacaagcttt
    13381 gctagaggga ttcaggaaga gctatttaca caggaacaat tttatttcat tgctgaaggg
    13441 atttcatctg atggagggtt agataaagat attgataagg taggcttgtc aacacttgaa
    13501 cgttctttta gggcgcttat ttatgtaaat ctcttgtctg ctgatgccaa ccagcaatcg
    13561 attttctatc agagattaaa atcagagatt cgcaatgtcc ttttaaatca aggcttgtat
    13621 tatctttcaa aagaaaagga tacaaggggt ttttcaagtc agtatggttg ggttcatgct
    13681 tttgcacatg gagccgattt actgacagag gtggtttgtc atccaaactt tcctaaaacc
    13741 agagttcatg aagtatttga catacttggt caattattta aaagaattac cattcgtttt
    13801 acagatgatg aagattggcg tttagccaga gtgctttatg aaccgatttt acaagggaag
    13861 ttggagcaag agcaagtagc ttcttggata aaaattgttg attttccgat agaagaaagg
    13921 gaagattttt acaaattttc caatttcaga tcctgtctct cagaagtcta tgtacaactc
    13981 gaccagagaa atagtttaca agatgacttg aaagaagcta tccagtcttt tcaatactag
    14041 ggataagcta atagctctat gattttcaaa aaatttccaa tcaattttct tgaaaccctt
    14101 tccctgccag aagtccgaga atgacattga ctgaatcttg ttggagttta gagaggcgat
    14161 aagaacctct gatagcggct tgaatggttt gagcaagctt ctcagagtcc ttaaaatgcc
    14221 ctttacccag ttgttggagc caatcagcta attcttgaag aggcatgtta gcaagttcgt
    14281 ctaaggtcat ctcatct
//
LOCUS       DAVDZK010000047        13958 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVDZK010000047 DAVDZK010000000
VERSION     DAVDZK010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13958
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.048"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            91..161
                     /locus_tag="VUX16_001844"
     tRNA            91..161
                     /locus_tag="VUX16_001844"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:123..125,aa:Cys,seq:gca)
     gene            complement(359..1690)
                     /locus_tag="VUX16_001845"
     CDS             complement(359..1690)
                     /locus_tag="VUX16_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET8124750.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(1981..2805)
                     /gene="endA"
                     /locus_tag="VUX16_001846"
     CDS             complement(1981..2805)
                     /gene="endA"
                     /locus_tag="VUX16_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET8124751.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     APEAPSQELAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGTYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(2844..3032)
                     /locus_tag="VUX16_001847"
     CDS             complement(2844..3032)
                     /locus_tag="VUX16_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET8124752.1"
                     /translation="MNKKSGYVIKRLLLVILVLILGLLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(3025..4308)
                     /gene="murA"
                     /locus_tag="VUX16_001848"
     CDS             complement(3025..4308)
                     /gene="murA"
                     /locus_tag="VUX16_001848"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET8124753.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASERETVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(4332..4562)
                     /locus_tag="VUX16_001849"
     CDS             complement(4332..4562)
                     /locus_tag="VUX16_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET8124754.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(4620..5657)
                     /locus_tag="VUX16_001850"
     CDS             complement(4620..5657)
                     /locus_tag="VUX16_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET8124755.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMVYAWLTPFTDIRSVQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPALRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGGAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(5641..6129)
                     /gene="coaD"
                     /locus_tag="VUX16_001851"
     CDS             complement(5641..6129)
                     /gene="coaD"
                     /locus_tag="VUX16_001851"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET8124756.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(6119..6658)
                     /gene="rsmD"
                     /locus_tag="VUX16_001852"
     CDS             complement(6119..6658)
                     /gene="rsmD"
                     /locus_tag="VUX16_001852"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET8124757.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(6723..7715)
                     /locus_tag="VUX16_001853"
     CDS             complement(6723..7715)
                     /locus_tag="VUX16_001853"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET8124758.1"
                     /translation="MKKSFIHQQEEISFVKNTLTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(7826..8509)
                     /locus_tag="VUX16_001854"
     CDS             complement(7826..8509)
                     /locus_tag="VUX16_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET8124759.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFFASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(8565..9305)
                     /locus_tag="VUX16_001855"
     CDS             complement(8565..9305)
                     /locus_tag="VUX16_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET8124760.1"
                     /translation="MTIITSKANSVVKNTKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQREEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            9339..9617
                     /locus_tag="VUX16_001856"
     CDS             9339..9617
                     /locus_tag="VUX16_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET8124761.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYPDFKIAN"
     gene            9695..10621
                     /gene="yidC"
                     /locus_tag="VUX16_001857"
     CDS             9695..10621
                     /gene="yidC"
                     /locus_tag="VUX16_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET8124762.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFASQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIINYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(10696..11490)
                     /gene="pflA"
                     /locus_tag="VUX16_001858"
     CDS             complement(10696..11490)
                     /gene="pflA"
                     /locus_tag="VUX16_001858"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET8124763.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(11604..12866)
                     /locus_tag="VUX16_001859"
     CDS             complement(11604..12866)
                     /locus_tag="VUX16_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET8124764.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYTRELGATINLDAFEDIEHLERAAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTPAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKKTYRTYLGVDASAINLMRPAMYGAYHHITNLTHPDGPAEVVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     VRQIRRAERPKDYFATLYGFDFEEESEK"
     gene            complement(12933..13760)
                     /gene="purR"
                     /locus_tag="VUX16_001860"
     CDS             complement(12933..13760)
                     /gene="purR"
                     /locus_tag="VUX16_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET8124765.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQVIDVEVGNIFDEDK"
BASE COUNT         4073 a         3273 c         2594 g         4018 t
ORIGIN      
        1 ttggcatcac attcgaatca cgctatggta caaaaaactg aaaaaactat tgactgaaaa
       61 tcattttcaa ggtataataa taaacgttaa ggcggtatag ccaagtggta aggcacggct
      121 ctgcaaaagc ttgatcgtcg gttcaaatcc gtctaccgcc ttctataact tgatttatca
      181 ggtttcaaat gaacagaaag cccaatttga agggcttttt ttattttccc tcgaataaat
      241 acgtataact ttaaaaactt ttggagcgag tttgtggcag agttctttcc atggcataat
      301 tcccttttga aatcaattga aaaaagcttc gtcacgcctg gtgacaaaag cctctagttt
      361 attctgtttc ttcttctatt tcgacttctg tgatttggac ttttaccttg gtaacacgtc
      421 cattcttcac tttatcattg gttaagataa actgtttgtt ttggctgacc aattcatagc
      481 tgagtttctc agtcgttgga atggttccca ctcctgtcaa ataataacca gcgatggtat
      541 caacgtcatc actttccagt tcaacatcaa agtaattatt gaaatcattg agggtcatag
      601 ttccttgaac aatgtaggta tcctcgccaa tctgatgaac atctattgct gctttgtccg
      661 tttcatcatc aatttcacca acaatttcct ctaagaggtc ttccaaagtc accaaaccag
      721 ccataccacc gtattcatcc agcaagattg ccatttgtct ttgggtattt cgcagttctt
      781 ttagcaagtc atccacaaaa atagtttcag gtacaaaaag tggatcttgt aaaattctct
      841 tccaaacaat attgtcaaaa ccgtccacaa agcctgcctt aaggagactc ttggtgtgaa
      901 tgattccaat tacattgtcc ttatccccat cataaaccgg gatacgagaa taattttgtt
      961 ttaaaatact ttggataatg gcttgactat catcctgaat atccaccata aaggcatccg
     1021 ttcgaggaac cataacctct cgtgccatca gttcatcgag cgaaaagaca ccttgtagca
     1081 tctcaatctc atcagcatcc aatgtttctt cactatttgt caacatatag gcaatttcat
     1141 cacgggtcat cttttcatcc gcatcatcga atgacatagg agtcaaatgg ctcaagaaat
     1201 tggtcgaagc agctaaaagc caaacaaaag gactgactag ttttccgatc ccaatgataa
     1261 tcggcgctgt acgaattgcc aaggcatcct ttagattaag agcgattctc ttaggatata
     1321 attccccaaa aacgatggaa atataggtca aaaatgccaa ggatagaaaa gttgccacgg
     1381 cttgtgctgt ttcgccattc ccaagccaag aggcaatcac acgtcctaga gtatcagtta
     1441 aactcgcccc tgataagatt gtaatcaggg tgattcctac ctgaatggtt gataaaaagt
     1501 ggttaggatt ttctagtacc ttcagcaggc ggatgtagcg tctgtctcct tcttccgcct
     1561 tttgttcaac tcgggcacga ttaagagaaa ccatggccat ttctgtggct gagaaaaagg
     1621 catttaatac cgtcaagata aacaataaaa caaattgtag caacaaattc tgactacttg
     1681 ggtcttccat agttcttctc ctaaaatagt atcttatcct ttattatatc acaaaattta
     1741 atccaataca tattattttt ttcttagcgt aacttccatc tctctcccaa aactggaagt
     1801 tagtctaaga cggatttcca ctgatttcac gcgtttttct catactaaaa gctaggttgt
     1861 gggaaactgg aagttagttt tagaagttac cattttttct tagtacctat tctagccctg
     1921 cttaaactag taaaaagaac tcctacatcc ataagtgaca taggagttta ggcttatctt
     1981 ttactgagtt acagttactt ctccagttcg gtaatccagt tgaagtccct tttgaacatt
     2041 gggaactaga acattgaatt ccaattctcc atccgaagac ttggcttcaa tctgtgaagc
     2101 tgagggaact aaatcctcgt ttgaagcgta gtaaagggtt acacggtaac ggacacgctt
     2161 gttttggtcc aaggctttac gcaccttgct ttcatagtag ttttgaccag tcgaatcctc
     2221 ggcttgtgcc tgatttgccc aggctgtttg aacagcaatg tttttaggat tgcttgtcga
     2281 ggcatcaaaa ccatccaagc caccgattaa ggcatagcct aacaagtgac ctctatcgac
     2341 cgcatgggta taagtcccct ttagattctt gacctgatgc caacctggag gagtccaaga
     2401 agttgaacca ttcccagttt cttcacgatt cttgtactga cgagtggcct tagacaaaag
     2461 ggcattagct acggttggaa cagtttcctt gcccactgtc tttgttttat tgtcagcgta
     2521 gggcttactt gaaaccttgg catctagatt tgttttatta ccattgacga taaaagcacc
     2581 tgagccattc cactccagac tcccctttat ttgactcttg actgcgtctg ttaagacact
     2641 ttctgccaat tcttgactag gagcttcagg cgcttgtttt ttctgactaa gattggtttt
     2701 gggactatta ggtgccgact gcatctgctt gatataatag ctccctgtag acaaaagcaa
     2761 taacactagc agtccgatta gtgtctgtct tgtttttttg ttcatatttc tccttatctt
     2821 tagaaaaagg ctggttctcc agcctaattt cctgtaaatt tatgaatcaa ttcctgccat
     2881 tttgccggag acaggatagc ccacggatct tgacccttgc ccaagattcc atagcctacc
     2941 attaaaccga ttcctaaggc tagaaggcct aaaatcagta ccagaatgac taaaagtaaa
     3001 cgcttgatta cgtaacctga tttcttattc atcttcatca cttgcctcaa tccgctgaat
     3061 cttagcacct agctgcgcca acttctcatg gaaaccgtag taacctctat ccaagtgaac
     3121 caatttaccg accacagttt ctccctgtgc taccaaacct gtcaaaatca aagctgcact
     3181 ggcacgaagg tcagttgaaa gaacttctgc tccctgcaaa ggctgtccac caacaatacg
     3241 agctgtatca cggataatct cagaatgcaa gcccatgcgg cgcatctctt ctaggtgttg
     3301 gaaacgattt tcgaaaactg tctccaccat ggttgattcg ccttttgcaa ctgtcatcaa
     3361 ggctgtaaat tgagcctgca tatctgttgg aaatcctggg tggggcaagg ttttcacatg
     3421 aacagctttt agattttcta gttgagaacg aacacgaatt ccttcgtctt cttcaattac
     3481 ttcaacaccc atttcaagta acttggcaat caagggacgg ttgtgctccc agacagcgtc
     3541 tcgaatcaag acatcaccac cagtcatggc agcagctacc ataaaggttc ctgcttcgat
     3601 acgatcttgg actacattgt gagtcgtacc atgaagtttc tcaacaccag taatggttat
     3661 agtctctgta ccagcacctt tgaccttggc tcccatttca ttaaggagaa tggctaagtc
     3721 aacaatctca ggctcacgcg cagcattctc aatcactgtc accccatcag ccagagtcgc
     3781 tgccatcatc aagttctgcg ttgcaccaac acttggaaag tccatataga tatgagcgcc
     3841 atgcaagcgt tctgccttgg cttctatgta accagctgtc tgactaatct taacccccat
     3901 agcttccaga cctttcaaat gaagatcaat aggacggcta ccaatcgtac aaccacctgg
     3961 catggatacc ttggcatgac ccacacgggc aaggattggc cctaatacaa cgatggaggc
     4021 gcgcatcttg ctgacatact tgtaaggggc ttcctcagtg atgtcgccag tagcatccac
     4081 cttgacaaga tgagcttcct catcaaagtc aaccttggca ttcaaaccac caactacctg
     4141 attcataata aagacatccg acaaaatcgg aacattctgc aagacggtct ctctttcact
     4201 tgctagaata gtcgctgcca acaagggtaa gactgcattt tttgctccct cgatcgtcac
     4261 gcttcctacc agacgattat cgccaccttg aaccacaatt ttatccatac tcgtttcctt
     4321 tactcttgat tttataataa tcctctaagc gcttcttgcc acaaatgata caggctaata
     4381 aagaaagaac tcaggatgta gcctatgaca atgctaaaaa aggctactaa taaacgaact
     4441 tttcttgtat tatcatctgt cacttttaaa accttctccc atctaacaag atcctttaaa
     4501 aggtaaaaac tcacataaat aaagagcata tgactactta gagtgaataa taattgaacc
     4561 atttgactat tataccatct tctctgtttg tgcgctagtt tggaaacttc actcaaaaat
     4621 tagggattgt ttttcaagta atcaatcgca tcttgtaggg ttttaacggg cacgattttc
     4681 atatccgtct tgattgtttt agccgcttct agggctgttt ggtagttgtt tttcgcgtcc
     4741 ggatgcgcct tttgttcttc ttcgctaaca gggttatcag gagcaaagaa aatagcacca
     4801 cctgccctag ccgaagctac aaccttctta tcaatacctc caatgtctcc cacattacca
     4861 tcgcggtcaa tggtacctgt accggcaaca atacgaccat tacgaagagc tgggtgagct
     4921 atttgagtat agatagctag actaaacatg agaccagcac ttgggccgcc aataccagct
     4981 gttgaaaagc taattgggac attgctgatt acctctgtac gatcaatcaa gccgattcca
     5041 atcccatttt ttccattttc caaggtgata atctttcctt ctgcagactt ggtttgccca
     5101 tcctcttcat aggtgacctt gacggagtcc cctaattttt gagaactgac gtaatcaatc
     5161 aagtctttgg aactatcaaa ggtctgatca ttgactgctg tgaccgtatc agagatattg
     5221 agaatccctt taaaggttga attatccgtc acattcaaga cataaacccc aaagtacttg
     5281 agttcgatat ccttaccagc tgtttttaga ccttgatact tggccatatt ttgtgatgtt
     5341 tgcatgtaga attgattgat tcgcataaat tctacatcgg aagaaccacc tgtggtctcc
     5401 tgaacactac gaatatctgt aaaaggcgtc aaccaagcat aaaccatatg agctaatgtg
     5461 gcatgttgaa caccaaccgt aacgaattga taggcaccag cttccttatc ttctgtgtca
     5521 tttactttaa ggacttggcg aatatcttcc gaaccacctg gaacctctat ataataaggc
     5581 aagggcacta caaatgccaa gaaagtcaca atcaaggccg caatgacgta taagggccat
     5641 ctaatctttt ttttcatttc ttatttcctc caaaatactc tcgggaacat agcaggcaat
     5701 atcctgacca aacttcaaaa gctctctaac gcctgatgaa ctgatataga gatgttcagg
     5761 tcgactatgt aaataaatag tctctatatc agaagacagc tgatgattgt agtaatcaaa
     5821 actggcttca tattgcaaat ccgacgcatt cctcaaacca cgcactagac aagtagcacc
     5881 caatcttttt gcaacatcga ccaccaattc atcatgagaa gccacgactt caacattttc
     5941 caaatgtccc aaagcctttt ctagcccccg tttacgattt tcaagaggga gaaatccttg
     6001 tttgtgggga ttaaaaaaaa tacccacaca aagcttatca aaaagtctgc tcgcccgttc
     6061 aatgatatcc agatgcccat ttgtcatcgg atcaaatgag cctgtgaata agccaatctt
     6121 atctgacata gactgtcacc ttactaattc cataaatctt ttccttccag atacccagac
     6181 aggcaatctc ttctggaagt tcaacggcct tatccgtctc gcacacaacc ataacatctt
     6241 cagaaaaaag ctctctctca gccatttttt caatatctgc tacgatttgt tccttggcat
     6301 agggagggtc taagaaaacg aggtcaaatt ccccagatac ctgttccaat gccctctctg
     6361 catccatctt gaggagttga aattttccaa cttccttggt catctggata ttttcagcca
     6421 cgatggtctg agccttacgg tctcgctcca ccaaaacagc actggacatg ccacgcgata
     6481 ctgcttcgat agataaacca ccactacctg cataaaggtc caagactcgt cccccttcaa
     6541 agtagggacc aatcatgtta aaaatggctc ccctaacctt atccgaagta ggtcttgttg
     6601 tcttgccttc tagtgtcttg aggggacgtc ccccatagat tcctgatacg attttcatac
     6661 tgtttattgt accaaattat agacaaaaag agaaagaaaa ccgaaccttg cggttcgatt
     6721 ctctacaaaa tattttcgta agtatcgcgg acttcttgag gccaaacact tgtttgcact
     6781 tctccgatgt gtctcttgcg aagtaggaac atggccatac gagattgtcc aattcctcca
     6841 ccgattgtca atgggaatag gccattcaac aaagacttgt gccattccaa ttccaagcgg
     6901 tcttcatcac ctgtaatttc cacctggcgt ctaagagttt cttcatctac acgaattccc
     6961 atagaagaca actcaaaggc tccacctaaa gactcattcc agacaagaat atcaccattt
     7021 agacccttgt agccattctc agactcgctt gtccagtcat catagtctgg tgcacgtcca
     7081 tcgtgcggtt taccatctgg caactcgcca ccgataccaa tcaaaaagac ggctccaaat
     7141 tctttacaaa tcgcattttc acgttctttc ggtgtcaagt ctgggtagcg ttctaccaat
     7201 tcttctgtat ggataaaggt gatttgtttt ggcaagatag actcgatgtc atagcgagct
     7261 tcaacagcta gctcagtcag gcgaatagcc ttataaatct tctcaactgt ttcttttaga
     7321 taaacgatgt tacgcttacc atttgggata accttctccc agtcccactg gtcaacataa
     7381 acagagtggg ttgcatccaa ggaatcctca tctggacgaa gggctttcat gtggacaaag
     7441 agaccctctc cttcaccaaa gccaaaacga gccaaggtgt ggcgtttcca tttagcaagt
     7501 gagtgcacca cttcataagt agcatcaggg atttggagaa ccttgaccga tactggattt
     7561 tccacaccag acaggttgtc ctgcattccg tcaccgacct tactcaagat aggaccttga
     7621 acttcgacaa cttctagctt atctttcaaa tactgggtca aagtgttttt gacaaaggaa
     7681 atttcttctt gttgatggat aaaacttttc ttcatagaca actcctcaaa aatttaataa
     7741 acgtattata cacctatttc caagaaaaga aaagagaaaa tttaaaaaaa tcagtgtcac
     7801 tcaaaacact gatttcatag accttttagt cattgcgacc aaagatacgt agaatactta
     7861 ggaaaagatt gataaaatca agatagatgc tgagagccat tgacaccacc cagcctgtcg
     7921 ctacacgacc ttgtgattgt tcataggcga ggcgaatctt ttggttatcc caagcaatca
     7981 accctgaaaa aaccaaaacc atggctacgc taatcatata atcaaagaag ccactagcaa
     8041 agaaaatatt gactaccata gcaatcagta aaccaatgag agctgccatc attgctcgac
     8101 caatcccact caagtctttc ttggtaaaga taccaactgc cgccatgaca aagaagagaa
     8161 gggcgctcga tacaaaggca gataaaactg tacccggagt atagaaagcc accacaaaac
     8221 taagggtaaa gccgtttaaa acggagtaaa gtaaaaatac tggaagagca gctggactat
     8281 ttcttgaagc catgctactg gcaacgaaaa ccaaagccaa ctccgcaaaa gtagcaatgg
     8341 tcaaccagag acgcccctgc atcaaaaagt aaaccaactg agactgaaag accgtcaaca
     8401 taaggcctga taccaaagca gatagtccga ttcccagacc aacaaaggca taaaccttag
     8461 cgtaaaattg attgagacct gcacggtcat gtataatagt gtgattcatc catttctcct
     8521 tttctgtgaa catctttcct tgattataac aaaaaaagtt aaaattagct taaatggaag
     8581 attaaaatac cggctgcaac cgcaacattc aaactctcgg cctgcccctt catgctaata
     8641 tggaccaact ggtctgcact ttcagccata aggggactaa ttccttgacc ctcatttccc
     8701 ataactagta caaaattttc tatagaaggc agttctctgt aatcaacaga atctttagat
     8761 agggttgttg ctagcactgg gatagctacc tttttagttt cgtcaagaag cgcttgacta
     8821 gtcatccggt aaatgggcag atggaaatga ctaccttgca tggaacgtag ggttttgaga
     8881 ctgtagatgt ctgccgactt atctgaaaca atcactcctg taaaacctgc tgcatccgca
     8941 gttcgaatga tagttcctac attaccagga tcttgcacat cttccaaaaa caagaacttg
     9001 ccctgactca aatcagcttg tcctacttct tctctttgaa ccacggcaac aattccctgt
     9061 ggagtctgag aatccgccaa atctagcaaa atatcctctg acacccagac agtttgcgaa
     9121 aaagtagcta actgatctcg ataattttct agggtaaaga ttttctcaat cgtcactcca
     9181 gcttgaacag cttcttcaaa caagtgccag ccttcaatta aataggcaga cttgcggtat
     9241 tttttttggt gtaatttctt ggtatttttt acaacagaat tggcttttga ggttataata
     9301 gtcatagaaa tattataaca caatcaaagg ggtttggtat gcaaaaggtt agaatgattg
     9361 cccaaggtag ggtgcaggga gtcggctttc gttggggtgt ttatagcctg gcccttgaaa
     9421 tcggtggcat cacaggtcgg gtatggaata acgacgatgg cacagtggaa atcttagccc
     9481 aagcagactc atctgctatc atggcaaaat ttatccaaga aatccgaaaa ggaccgacac
     9541 ctttttcaaa agtcagttac ttagatgtca aactgagcaa ctttcctccc taccctgact
     9601 ttaaaatcgc aaattaggtc tccagaacta ttgtatattt tgtaaaaaaa cagtagaata
     9661 gaaaggtata atttttaaag aaggaataaa aacagtgaaa tctattaaac gttttgcatt
     9721 ctcggctatg ggagtggcta tgttgcttgt cttgactggc tgtgtcaatg tcgataaaac
     9781 cacaggtcag ccaacaggat ttatttggaa tacgatcgga gcgcctatgg ctgaagccat
     9841 caagtacttc gctactgata aaggtctagg ctttggtgtc gctatcatta tcgtaaccat
     9901 tatcgtacgc ttgattatct taccacttgg tatctaccaa tcatggaagg caacgcttca
     9961 ctctgaaaag atgaacgctc tcaagcatgt ccttgagcca caccaaacac gtctcaaaga
    10021 agcaactact caagaagaaa aactcgaagc ccaacaagcc ctctttgccg ctcaaaaaga
    10081 gcacggcatc agcatgtttg gtggtgtagg atgtttccct atcctccttc aaatgccttt
    10141 cttctctgct atctactttg cttcccaaca tactgaaggg gttgctcaag caagctacct
    10201 aggcattcct ctaggttctc caagtatgat tttggttgcc tgtgctggtg tcctttacta
    10261 tcttcaatcg ctcctttcac ttcacggagt agaagatgaa atgcaaagag aacaaatcaa
    10321 gaaaatgatt tacatgagcc cactcatgat cgtcgtcttc tccctcttct caccagctag
    10381 tgtcacactt tactgggttg tcggtggttt catgatgatt ctccaacagt ttatcatcaa
    10441 ctatatcgtt cgtccaaaac ttcgcaaaaa agtccgtgaa gaactagcca agaacccacc
    10501 aaaagcaagt gctttctcta aaccaagtgg acgaaaagac gttacccctg aacaaccaac
    10561 tgctatcaca agcaagaaaa aacacaaaaa tcgcaacgct ggaaaacaac gttcgagata
    10621 agaagaaaaa ggcttagctg atttgctaag tctttttgca aatcaaaagc ccgatgtttc
    10681 catcaggctt cttttctatc catgtacacg tttcatataa tcttgataac tttcggtatc
    10741 catgagtttt ttagcgttct tgacgcgatc tgctgttggt ggtttgactc cttcgaggga
    10801 atatggaatt ccaagttcac gccacttgaa ctcacccatg gtgtgataag gtagaatttc
    10861 aaacttatca acatttttga gggtcttgac gaacttacca agttcaatca agtcatcatc
    10921 tctgtctgtc aatcctggaa ctagcacatg gcgaatccag acaggttttc caatatctga
    10981 tagatactgg gcacaagcca agatattttt attggtttgg ctagtgacaa tcttgtgctg
    11041 ttcttcgttg atttccttga tatccaaaag aaccaagtca gtgacagcca tgagtttgtc
    11101 aaacttctca aggtaacgtg gtttattacg gaaaggaaga gcacaggtgt ccaaggtaca
    11161 gtggattcct tgttccttag ccttggtgaa gagggcaatc aggaaatcaa tctgcaagag
    11221 agcttctcct ccactgactg taatcccacc cttatttccc cagaaaccac ggtagcgcaa
    11281 ggcctctgtc aagacatcat ctaccgtccg ttcacgtgac ttattggact ccatagccca
    11341 agtgtctggg ttgtggcaat actggcaacg catgtgacag ccctgcaaaa aaacaataaa
    11401 gcgaatacca ggcccatcta ctgacccaaa gctttctgtc gaatgcacca ttcctgtcac
    11461 ttgtccataa tcaattgttt cttcagacat atcgttacct tccttgaaaa cgttttatag
    11521 ttttattata tcacgacttg aaggaaaaac aaggtttttg cctatttttt agaaagcaat
    11581 ctgtttttca atttcatttt caattacttc tcagattctt cttcaaaatc aaagccatac
    11641 aaggttgcaa agtagtcctt aggacgctct gcacggcgga tttgacggac tttgccttct
    11701 tcagtataga ggatttccgc agaacgaagt ttggcattgt actggtaacc cattgaaaat
    11761 ccatgggcac ctgtatcatg aatgaccagc aaatcaccga tttctgtatg aggcagttcg
    11821 cgattcactg caaatttatc attgttttca cagagtgaac cgaccacatc taccacttca
    11881 gctggtccat ctggatgtgt cagattggta atatgatggt aggctccata catggctgga
    11941 cgcataaggt tgattgctga tgcatccaca cctagatagg tacggtaggt tttcttctta
    12001 tgagtgactc ttgtgaccaa agctccgtga ggtgccagca taaaacgacc caactcagta
    12061 aaaatcttaa cctgaccaag acctgctggc gtaaggacct cttcatacac cttacgaact
    12121 ccctcaccaa tcaaggcaat atcgttcggc tcctggtctg gacgataatt aacaccaata
    12181 ccgccagaaa gattgataaa gtctaacgaa atgcccaact tttccttgat ttcaacagcc
    12241 agttcaaaga gctgacgagc caactctgga taatagagat gggtcacggt attggacgct
    12301 aggaaggagt gaagcccaaa agtcttggct cctttttcct tcaagatagc aaaggcttca
    12361 aagagctggt ccttggtcat gccaaactta gcctccccag gattgtccat aatgtctgtc
    12421 cccagttcaa aaacgcctcc aggattataa cgacaagaga tgatttctgg aatgcctgct
    12481 gctctctcca gatgttcaat atcttcaaag gcatccaagt taatggtcgc acccaattca
    12541 cgtgtatagg cgtattcctt gtctggcgtg ttgttggaag agaacataat ctcagaaccc
    12601 agaaagtcca gtttatggct catcaaaagc tctacataac tagagcagtc cacaccacaa
    12661 ccttcttctt ggagaatttt caaaatagct ggagttggag tagccttaac tgcaaaatat
    12721 tccttaaagc ccttgttcca cgaaaaggct tggttgacgg ctcttgcctt ctcacgaatc
    12781 cccttctcat catacaagtg aaagggagtc gggaactcgg caacaatcgc ttctaactct
    12841 tctctattaa taaatggtgt tttcataagc ttccttctat tctgtttgca aagaaaggct
    12901 gggacaatcg ttccaacctt tagttctatc tcttatttat cttcgtcaaa gatattgcca
    12961 acctcaacat cgatgacttg gttcttgaca tcaatattgg ttaccttcaa gagtgacttg
    13021 tagtcaaact gcttttcacg ttcttcttgg gcattgtccg caaagaccgc tacacctgcc
    13081 agttctgagt cgaactcgcg caagagacta atcatcccgt tgacagttcc gccacctttc
    13141 aagaagtcat ccacaatcaa gacacggctg cctgccttga gactgcgttt tgaaaggaac
    13201 attttctcga tacggtcacc acttgaacct gaaacatagt tgacgctaac agttgaacct
    13261 tcggtaattt tcaggtcacg gcgcacaatg acaaaagaga cattgaggac attggcaact
    13321 gcatttgcaa gtggcacacc cttagttgct acggtcataa ccgcgtcaat tttttggtcc
    13381 ataaagcttt tggcaataat acgaccaata tttttcaaga tggctggtgt gctaagcaaa
    13441 tcagacagat agatataacc acctggcaag atacggtcac tttctgacaa cttggtacgc
    13501 aagtcttcaa ccatttcctt agcatcctga ctcgaaatag acggtgtgaa gatgacacct
    13561 ccgccagccc cagtcactgt ctggatatga ccgatttcaa tttcctcaaa ggcgcgtttg
    13621 ataatgacga tatcttctga gatggatgat ttagcagact catacttttc agcaaaagta
    13681 ttgagactag ttagtttata aggattatta atcaaatagt tggaaatgac aaccatccga
    13741 tcacttcttc ttaatttcat ttctatttcc tattccattt ttattcaaaa aatcaaaaag
    13801 caaactagaa agctggtcgc tggtggttca aaacactgct ttgagattgt cgatagaact
    13861 gacaaaccct gtaatatacc tgcatatata catacgacaa ggcgatacta ccctagtttg
    13921 aagagatttt cgaagagtat tcatttttgt cttttact
//
LOCUS       DAVDZK010000048        13805 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVDZK010000048 DAVDZK010000000
VERSION     DAVDZK010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13805
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.049"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            92..2428
                     /locus_tag="VUX16_001861"
     CDS             92..2428
                     /locus_tag="VUX16_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET8124766.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNLAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            2530..3207
                     /locus_tag="VUX16_001862"
     CDS             2530..3207
                     /locus_tag="VUX16_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET8124767.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            3194..3991
                     /locus_tag="VUX16_001863"
     CDS             3194..3991
                     /locus_tag="VUX16_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET8124768.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQEDDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIATLLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            4008..5111
                     /locus_tag="VUX16_001864"
     CDS             4008..5111
                     /locus_tag="VUX16_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET8124769.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEVSHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            5367..6386
                     /gene="galE"
                     /locus_tag="VUX16_001865"
     CDS             5367..6386
                     /gene="galE"
                     /locus_tag="VUX16_001865"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET8124770.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGIIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            6388..7353
                     /locus_tag="VUX16_001866"
     CDS             6388..7353
                     /locus_tag="VUX16_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET8124771.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRHFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRILILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(7404..7610)
                     /locus_tag="VUX16_001867"
     CDS             complement(7404..7610)
                     /locus_tag="VUX16_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET8124772.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDGPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            7661..8137
                     /locus_tag="VUX16_001868"
     CDS             7661..8137
                     /locus_tag="VUX16_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET8124773.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSHPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            8146..8817
                     /locus_tag="VUX16_001869"
     CDS             8146..8817
                     /locus_tag="VUX16_001869"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET8124774.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            8948..9286
                     /locus_tag="VUX16_001870"
     CDS             8948..9286
                     /locus_tag="VUX16_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET8124775.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            9289..9918
                     /locus_tag="VUX16_001871"
     CDS             9289..9918
                     /locus_tag="VUX16_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET8124776.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            10158..11309
                     /locus_tag="VUX16_001872"
     CDS             10158..11309
                     /locus_tag="VUX16_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET8124777.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            11622..12371
                     /gene="truA"
                     /locus_tag="VUX16_001873"
     CDS             11622..12371
                     /gene="truA"
                     /locus_tag="VUX16_001873"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET8124778.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            12361..13134
                     /locus_tag="VUX16_001874"
     CDS             12361..13134
                     /locus_tag="VUX16_001874"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET8124779.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNVGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            13112..13573
                     /locus_tag="VUX16_001875"
     CDS             13112..13573
                     /locus_tag="VUX16_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET8124780.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNDWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         3832 a         2663 c         3226 g         4084 t
ORIGIN      
        1 tcaaaggagg gctggcaaac ttttcccttg actagatgca tatttgggat gaaattagaa
       61 ttttgttaaa aaaaatgata taatagaatt tatggataaa aataagatta tgggattaac
      121 ccaaagagaa gtcaaggaaa gacaggctga gggtttggtc aatgacttta ccgcatcagc
      181 cagtaccagc acttggcaaa tcgttaaacg aaatgtcttt acccttttta acgctttgaa
      241 cttagccatt gctttggctc ttgcctttgt gcaggcttgg agcaatctgg tcttctttgc
      301 tgttatctgc tttaacgctt tttctgggat tgtgaccgag ctacgagcca aacacatggt
      361 ggacaagctc aatctcatga ccaaggaaaa ggtcaaaacc atccgtgatg gtcaggaagt
      421 tgctcttaat cctgaagaat tagtgctagg agatgtcatt cgtttgtctg caggagagca
      481 gattcctagt gatgccttgg ttttggaagg ctttgcggaa gtcaatgaag ccatgttaac
      541 gggagaaagt gatttggtgc aaaaggaagt tgacggctta cttttgtcag gaagtttcct
      601 agccagtggg tcagttttat ctcaagttca ccatgtcggt gcagacaact atgctgccaa
      661 actcatgctt gaggctaaga ccgttaaacc catcaactcc cgtatcatga aatcgctgga
      721 caagttggct ggttttactg ggaagattat cattcccttt ggtctggctc tcttgctgga
      781 agccttgctt ttaaaaggcc tgcctctcaa gtcatctgtt gtaaactcgt cgacagctct
      841 tttgggaatg ttgcctaagg gaattgccct tttgaccatt acttcgctct tgactgcagt
      901 gattaagttg ggcttgaaaa aggtcttggt gcaggagatg tactctgttg agaccttggc
      961 gcgcgtggat atgctctgtc tggacaagac gggcaccatc acccaaggaa agatgcaggt
     1021 ggaggctgtt cttccactga cggaaactta cggtgaagag gctattgcca gcatcttgac
     1081 tagctacatg gcccatagtg aggataagaa tccaactgcc caagccattc gccagcgttt
     1141 tgtgggagat gttgcttatc ctatgatttc caatcttccc ttctccagcg accgcaagtg
     1201 gggggctatg gagttagaag gcttggggac agttttctta ggggcacctg agatgttgct
     1261 ggattctgaa gtcccagaag ccagggaggc cttggagaga ggatcacgtg tcttggtctt
     1321 agctctcagt caggagaaat tagaccatca caaaccacag aaaccatctg atattcaggc
     1381 tctagccttg ctggaaatct tggaccccat tcgagaggga gcagcagaga cgctggacta
     1441 tctccgttct caggaggtgg gactcaagat tatctctggt gacaatccag ttacggtgtc
     1501 cagcattgcc cagaaggctg gttttgcgga ctatcacagc tatgtagatt gctcaaaaat
     1561 caccgatgag gaattgatgg ccatggcgga ggagacagct attttcggac gtgtttcccc
     1621 tcatcaaaag aaactcatca tccaaacgtt gaaaaaagcg ggtcatacaa cggctatgac
     1681 aggggacggg gttaatgata tcttggccct tcgtgaggcg gattgttcta tcgtgatggc
     1741 ggagggggat ccagcaaccc gtcagattgc caatctggtt ctcttgaact cagactttaa
     1801 tgatgttcct gagattctct tcgagggtcg tcgcgtggtc aataacattg cccacatcgc
     1861 cccgattttc ttgataaaga ccatctattc cttcctgtta gcagtcatct gtattgccag
     1921 tgctttacta ggtcggtctg aatggatctt gattttcccc ttcattccaa tccagattac
     1981 catgattgac cagtttgtgg aaggtttccc accattcgtt ctgacttttg agcgaaatat
     2041 caaacctgtt gagcagaatt tcctcagaaa atccatgctt cgtgccctac caagcgctct
     2101 catggtcgtc tttagcgtcc tgtttgtgaa aatatttggg agtagccaag gttggtctga
     2161 gttagaaatc tcaactctcc tctattatct cttggggtca attggtttct tatccgtatt
     2221 tagagcctgc atgccattta ccctatggcg tgtcctcttg attgtttggt cagtaggagg
     2281 tttcctagcc acagctctct tcccaagaat ccaaaaactg cttgaaattt caaccttgac
     2341 agaacaaacg ttgcctgttt atggtgtcat gatgttggtc tttacagtga ttttcatcct
     2401 gactagtcgc tatcaagcta gaaaataaag aaagactgca atctgtggat tgcagttttt
     2461 ttaggtacaa gattgccagc cgaaatgtgg tataataaga ggtaatagag ttttggaaag
     2521 tgagagaaga tgatttcaaa gagattagaa ttggtagctt cctttgtgtc acagggggct
     2581 attttactag atgtgggaag tgaccatgct tatctgccta tcgagttggt tgagagaggc
     2641 caaatcaaaa gcgctattgc aggtgaggtg gtggaaggtc cctatcagtc tgcggttaaa
     2701 aatgttgagg ctcacggcct aaaggagaaa atccaagtcc gtttagccaa tggcttggca
     2761 gcttttgaag agactgacca agtgtctgtc attaccattg ctggcatggg tggtcgtttg
     2821 attgctagga ttttagaaga aggtttgggg aagttagcta atgtagagcg tttgatcctc
     2881 cagcccaata atcgtgaaga cgacttgcgt atctggctac aggatcatgg attccagatt
     2941 gtagcagaaa gcatcttaga agaagctgga aagttttatg agattttggt ggtggaagca
     3001 ggacaaatga agctatcagc cagtgatgtt cgctttggtc ccttcttgtc caaagaagtc
     3061 agtccagtat ttgtccaaaa atggcaaaaa gaagctgaga agctagagtt cgccctcgga
     3121 caaatcccag aaaaaaatct ggaagaacgt caagttctag tagataagat tcaagctatc
     3181 aaggaggtgc tccatgttag caagtgaagt gatccaagct tatgaagcct tttgccctca
     3241 ggaattttct atggagggag acagccgtgg tctgcaaatt ggcactttag acaagggtat
     3301 ccaaagggtc atggttgccc tcgatattcg tgaagagaca gtggcagagg ccattgaaaa
     3361 gggtgtggac ttgattatcg tcaagcacgc gcctatcttt cgtcctatca aggacttgct
     3421 tgccagccgt ccgcaaaatc agatttacat cgacctgatt aagcatgata tcgcagttta
     3481 tgtcagccat accaatattg atatcgttga aaatgggctc aatgactggt tttgtcagat
     3541 gctaggaatc gaggagacga cttatctgca ggaaacaggt ccagaacgtg gaattggacg
     3601 tattgggaat attcagcctc agacattttg ggaattggcc caacaggtca agcaagtctt
     3661 tgacctagat agccttcgaa tggtgcatta tcaagaggat gatttgcaga agcctatttc
     3721 aagagtagca atttgtggtg gaagcgggca gtctttctat aaggatgctt tggcaaaggg
     3781 ggcagatgtc tatatcactg gtgatatcta ctaccatact gctcaggata tgctgtctga
     3841 tggcttgtta gcattggatc caggtcacta tatcgaagtg ctttttgtgg aaaaaatcgc
     3901 aacactcctt actcaatgga aagagaaaaa aggctgggaa ctagagattt tacctagtca
     3961 agcatcgacc aatcctttcc gtcatatcta gttagaaagt gaagacaatg aaaaaagttg
     4021 ccattattgg agcaggaatt gtgggagcaa cagctgccta ctacctctcg agagaaagtg
     4081 acctagaggt gaccgttttt gaccatgagc aaggtcaagc caccaaggcc gcagcaggaa
     4141 ttatcagtcc ttggttttcc aaacgccgta ataaagcctg gtacaagatg gcgcgcttgg
     4201 gggctgattt ttatgtggat ttattagctg atttagagaa atcaggacaa gaaatcgact
     4261 tttaccagcg ttcgggagtc tttctcttga aaaaggatga atccaatttg gaagaacttt
     4321 atcaactggc cctccagcgc agagaagaat ctcccttgat agggcaatta gccattctga
     4381 accaagcctc agctaatgaa ttattccctg gtttgcaggg atttgaccgc ctgctctatg
     4441 cttctggtgg agcgagagta gatggccaac ttttagtgac tcgtttgctg gaagtcagtc
     4501 atgtcaagct ggtcaaagaa aaagtgactc tgacaccgtt agcatcaggc taccagattg
     4561 gtgaagagga gtttgagcag gttattttgg cgacgggagc ttggttgggg gacatgttag
     4621 agcctttagg ttatgaagtg gatgttcgtc ctcaaaaagg acaactacga gattatcagc
     4681 ttgcccaaga catggaagat taccctgttg tcatgccaga aggggagtgg gatttgattc
     4741 cctttgcagg tgggaaatta tccttaggcg ctacccacga aaatgacatg ggatttgatt
     4801 tgacggtaga tgaaaccttg ctccaacaaa tggaggaggc caccttgact cactatctga
     4861 ttttggctga agctacttca aaatctgagc gtgttggaat ccgtgcctac accagtgatt
     4921 tctctccttt ctttgggcag gtgcctgact taactggtgt ctatgcagcc agtggactag
     4981 gttcatcagg cctcacaact ggtcctatca ttggttacca tctagcccaa ctgatccaag
     5041 acaaggagtt gaccttggac cctctaaatt acccaattga aaactatgtc aaacgagtaa
     5101 aaagcgaata atactcaata aaaatcaaag aacaaactag gaaactagcc gcgggttact
     5161 caaagcactg ctttgaggtt gtggatagaa ctgatgaagt cagtaaccat acccatggca
     5221 aggcgacgtt gacatggttt gaattggatt ttcgaagagt ataagcattt tactgaaatt
     5281 ttatcaggta gtttaggatg gcaaatgaca ttccctgtca aaaatggtaa aataagaaaa
     5341 aataatctga gaatcgagga aaaaagatgc aagaaaagat tttggtaact ggtggtgccg
     5401 gttttattgg aacccacact gttattgaat tgatccaagc aggccatcaa gttgttgtgg
     5461 tggataatct tgtcaatagc aatcgtaaga gtttagaagt tgttgaaaga atcacaggag
     5521 ttgagattcc tttctatgag gcagatattc gtgacacaga taccctcaga gatattttca
     5581 agcaggaaga accgactggt atcattcact ttgctggttt gaaggctgtt ggcgaatcaa
     5641 cacgtatccc tcttgcctac tatgacaaca atatcgctgg aactgtcagc cttttgaaag
     5701 ccatggaaga aaacaactgt aaaaacatca tcttcagttc ttctgcgaca gtttacgggg
     5761 atccgcacac agtgcccatc ttggaagatt tcccactttc agtgaccaac ccatacggtc
     5821 gtactaagct catgctagag gaaattttga ctgatattta caaagcagac tcagaatgga
     5881 atgttgtctt gcttcgttac tttaacccaa tcggagccca tgagagtggt gatttgggag
     5941 aaaatccaaa cggtattcca aacaatctct tgccatatgt gactcaagta gccgttggaa
     6001 aattagagca agtgcaagtg tttggagacg attacgatac ggaagatgga acaggtgttc
     6061 gtgactatat ccacgttgtc gatttggcta agggtcacgt tgcagctttg aaaaaaatcc
     6121 aaaaaggttc aggactaaac gtttataacc ttggaactgg taaaggttac tcagttcttg
     6181 aaattatcca aaacatggaa aaagcggtgg gccgtcctat tccttaccgc atcgtagaac
     6241 gtcgcccagg tgatatcgct gcctgctact cagacccagc aaaggctaaa gcagaactcg
     6301 gttgggaagc agaactcgac atcacccaaa tgtgtgaaga cgcatggcgt tggcaaagca
     6361 agcatccaaa tggatttgaa gactaagatg atgatttcaa tcatcgtccc ttgtttaaac
     6421 gaagaggaag tacttcctct tttttatcag gctctggaag ctttacttcc agatttggaa
     6481 acagaaatcg agtatgtctt tgtcgatgat ggatcaagtg atgggacctt ggaactctta
     6541 aaggcctatc gggagcaaaa tccggcagtc cattatattt ctttctctcg aaattttggc
     6601 aaagaagcag ccctttatgc aggcttgcaa tatgcgacag gagatttggt ggtggtgatg
     6661 gatgcagacc tccaagatcc tcctagtatg ttgtttgaga tgaaaaatgt actagacaaa
     6721 aatgtagact tggactgcgt tgggacacgg agaactagtc gggagggaga acccttcttt
     6781 cgcagtttct gtgctgttct cttttatcgc ctcatgcaaa aaatcagccc agtagctctg
     6841 ccgtcgggtg tccgtcattt tcgtatgatg agaaggtctg tagtcgatgc cattttaagc
     6901 ttgaccgagt ccaatcgttt ttcaaagggg ctcttcgcct gggtgggttt caaaacctac
     6961 tatttggact atccaaatgt cgaaaggcag gctggcaaga caagttggag ttttaggcaa
     7021 ctctttttct actccattga agggattatt aatttttcag atttcccttt gactatagcc
     7081 tttgtagctg gtctcctatc ttgttttctt tctctgctga tgaccttttt tgttgtggtt
     7141 cggatcctca ttttgggcaa tccgacatct ggttggacct ctctgatggc tgttattctc
     7201 tttcttggag gcattcaact cttgaccatt gggattctcg gtaagtatat cagtaagatt
     7261 tatttagaga ctaaaaaaag accactttat cttatcaaag aaaaaagtga ccttcctgat
     7321 tttacagaaa aaaataaagt gaaaagacta taattttaca tggaaatgtg ctaaactaga
     7381 gggagtggat tatcgccatt gatttaggct tcctggtttc caatcagggc gcgagttggg
     7441 caatttttaa cagcctctaa gacatcctga ctaggagaaa tttctttttc cagttggtca
     7501 gggccatcgt aaaaacgcac gattccatta tcgtggtaat caaataaatc agaataagtt
     7561 tggcaaagcc cacaggcgat acatcgttca ggtataagtg tgattttcat gttcatattt
     7621 atattgtaat aagaaaagta aaaaaaacaa ggagtaaggt atggcaaaag aaccgtggca
     7681 agaagatatc tatgatcaag aagaatcaag agcagggcgt cggcatcgaa accacggagg
     7741 ggctgatagg atggctaatc gtattttgac gatcctagct agtattttct ttgtaattgt
     7801 ggtggtgatg gtcatcgttc tcatctatct atcatcgggg ggaagtaatc gcacagcagc
     7861 cttaaaagac tttcatgatt ctgatgcaag tgtagtacaa atctcatctt caagcagttc
     7921 tcatcctgag cagagttcag agccagaatc tacttctagt agttcagaag aagctgctaa
     7981 tcctgaagga acgattaaag ttctcgcagg agaaggggaa gcagctattg ccgctcgtgc
     8041 aggaatctcc attgctcagt tagaggcctt gaatcctggg cacatggcta caggatcttg
     8101 gtttgctaat ccaggtgatg ttataaaaat aaaataggag ccgatatgaa aacaattcaa
     8161 attgctattg atggtcctgc ttccagcggt aagagtacgg tcgcaaagat tattgctaag
     8221 gattttggat tcacctacct tgatacagga gctatgtatc gtgcagcgac ctatatggct
     8281 cttaagaacc aattaggagt tgaagaagtc gaagcccttc tagccttgtt ggaccagcat
     8341 ccaatcagct ttggacgttc agaaactgga gaccagcttg tttttgtagg agatgtggat
     8401 attacccatc ctatccgtga aaatgaagtg accaatcatg tttctgctat tgcagcaatt
     8461 cctgaagtgc gtgagaaact ggtttctctc caacaagaaa ttgcccagca aggcgggatt
     8521 gtcatggatg gtcgcgatat tggaactgtt gtattgccac aagcagaatt gaaaattttc
     8581 ctagtagctt ctgttgatga gagagcagag cgtcgttaca aggaaaatat tgccaaggga
     8641 attgaaacag accttgaaac cctaaaaaag gaaattgctg cgcgtgacta caaggatagt
     8701 catcgtgaga cttctcctct caaacaagca gaggatgctg tctaccttga tacaactggt
     8761 ttgaacattc aagaagtagt tgaaaaaatc aaagcagaag ctgaaaaaag aatgtaaatg
     8821 tagaaaagcc gatagattga tatcggtttt tttctaaatt tgtcaaaatg ctgattttag
     8881 ggtataatag ttgctgttcg agaaattttg attttcaaag aatagtgaat gatgataagg
     8941 agaaaccatg aacaatttac caaattgtcc aaaatgtaac tcagagtatg tctacgaaga
     9001 cggtgcccta ctggtttgcc cagagtgtgc tcatgagtgg aatcctgctg aagttgcaga
     9061 agtagaagaa ggtcttgtcg ctatcgatgc caacggaaat aaattgactg atggtgatac
     9121 agtaactctc atcaaggact tgaaagtaaa aggtgcgcca aaagatttga aacaagggac
     9181 gcgcgtgaaa aatatccgca tcgtagaagg cgatcacaat atcgactgta agattgatgg
     9241 ttttggtgcc atgaaactta aatcagagtt tgtgaggaag atttaagcat gtcaaaacac
     9301 tataaacttg tattttatag ccgtatcttc ttgtttctag cggcttttac gggagtttat
     9361 cttgaaatta ctaggcatgg tggttttggg atgcttctct attacacggt tctgtccaac
     9421 ctcttggtaa ctatttttac cctttatctt ctaaaggtta tgagccgtgt aggtgaaaat
     9481 tggcaaaggc caagtctctt gcgcttaaaa ggtggggtca ccatgagtat catgattacc
     9541 tgtgtgattt accatttcct cttggcgccc attgcgacta atttctatac cctagaaaat
     9601 ttcctttgcc actatatcgt tcccatctgg tttttagcgg ataccctctt ttttgacaaa
     9661 cagggtcaat acaagatttg ggatccagca gtgtggacca ttttaccctt tctgtatatg
     9721 atgtttgctc tttttaatgg cttggttcta aaactcaata ttccaaatgc caaggataat
     9781 cctttccctt acttcttttt gaatgtgaac aagggttgga atgttgtgtt taagtggtgt
     9841 ctgattatct ttgttgccta tatggtagca ggatttattt tctactttat caagcaaatc
     9901 aagagaaagt catcctaata ctcttcgaaa atctcttcaa accacgttag tttccatctg
     9961 caacctcaaa acactgtttt gaacaacctg cggctagctt tctagtttgc tctttgattt
    10021 tcattgagta tgagatacaa gggattcatt ttcgaattta agaaggagtc tacaaaccaa
    10081 tgaggcttct tcttttcttg cttatttgat aactatcaaa aaagtagaag attaagagaa
    10141 atatagaaag agatttcatg aaacaatttt tagaacgggc cagcattttg gctctctccc
    10201 tcgttttgat tacctccttt tccatttcga gtgccctacc agccatgttt gactattatc
    10261 agggttattc taaggaacaa attgagctct tggtgagctt gccttccttt ggaatcatga
    10321 tgatgttact gctaaatggt ttcttagaaa aaatatttcc tgagcgctta cagattagtt
    10381 tgggcttgct gattttatca ttgagcggta cagctccctt ctggtaccaa gcctatccct
    10441 ttgtctttgg aacacggctt ctctttggtt tgggtcttgg gatgatcaat gccaaggcca
    10501 tttctattat cagtgaacgc taccaaggaa aaaggcgaat tcagatgtta gggctacgcg
    10561 cttctgcaga ggtcgttgga gcttctctca ttaccttggc cgtcggtcag ttgttggcct
    10621 ttggttggac agctatcttt ctagcctata gtgctggatt tttggtgatg cccctttatc
    10681 tgctctttgt cccttatgga aaatcaaaga aagaagtcaa gaaaagagcg aaggaagcaa
    10741 gtcgtttaac tcgagaaatg aaaggcttga tttttacctt agctatcgaa gcggcagttg
    10801 tagtttgtac caatacagct attaccatcc gtattccaag tttgatggtg gaaagaggat
    10861 tgggggatgc ccagttatct agttttgttc ttagtatcat gcagttgatc gggattgtgg
    10921 ctggggtgag tttttctttc ttgatttcta tctttaaaga gaaactgctc ctctggtctg
    10981 gtattacctt tggcttgggg caaatcgtga ttgccttgtc ttcatccttg tgggtggtag
    11041 tagcaggaag tgttctggct ggatttgcct atagtgtagt cttgacgacg gtctttcaac
    11101 ttgtctctga acgaattcca gctaaactcc tcaatcaagc aacttcattt gctgtattag
    11161 gctgtagttt cggagccttt acgaccccat ttgttctagg tgcaattggc ttactaactc
    11221 acaatgggat gttggtcttt agtatcttag gaggttggtt gattgtaatc tctatctttg
    11281 tcatgtacct acttcagaag agagcttagg attgattcct aagtttttct tttgatactc
    11341 aatgaaaatc aaagagcata gttgattgag tttggaatag tacgctgtag ctgctaaaat
    11401 atttctagaa attaatttga cttttctaat agagttattc atatcttatt tcaatctact
    11461 atagaaagct agccgcaggt tgctcaaaat agtgttttga ggttgcagat ggaaactgac
    11521 gtggtttgaa gagattttcg aagagtatga gatttttata cccatacaat atttgtttta
    11581 ggtccttgtt tacagactaa tttcttgata aaatagaggt tatgacgaga tataaagcaa
    11641 ctatttccta tgatggttat gcctttgctg gctttcagcg ccagtctcat gcgcgtagcg
    11701 ttcaggaaga aattgaaaaa accttgacca gattaaataa agggcaaacc attactgttc
    11761 acggtgctgg taggacagat agtggggttc atgccctggg acaggtcatt cattttgacc
    11821 tgccttatca gatggatgag gagaaactcc gttttgcctt ggatacccag tctcctgaag
    11881 atattgatgt gatttcgatt gagcttgtgg cagatgattt tcattgccgt tatgccaaac
    11941 atagcaagac ctatgagttt attgtggata gaggacgtcc caaaaatcct atgcgccgtc
    12001 actatgccac ccactttccc tacccactcg atgtggaacg aatgcagatt gcaatcaaaa
    12061 agctagaggg aacccatgat tttaccggtt ttacagcctc tgggactagt gtagaggata
    12121 aggttcgcac catcacagaa gctagtttaa tagtcgatga gacaggacaa tttttgacct
    12181 ttaccttttc aggaaatggt ttcttgtata aacagattcg caatatggtg gggactcttc
    12241 tcaaaatcgg taacaaccgc atgccagtag agcagattga tctcatcttg gagaagaagg
    12301 acaggcaact tgcaggtccc actgcagcac caaatggttt gtatttaaag gagattcgtt
    12361 atgaagaata atcgtatttt agcactttct ggaaatgata tttttagtgg tggtggactg
    12421 tcagctgatt tggctaccta taccttgaac ggcttgcatg ggtttgtagc agtgacttgt
    12481 ttgacagcct tgacagaaaa aggatttgaa gtctttccaa ctgatgatac catttttcaa
    12541 catgaattag atagcttacg tgatgtggaa tttgggggaa ttaagattgg tcttctccct
    12601 actgtcagtg tggctgagaa ggccttggac tttatcaaac aacgcccagg agtacctgtg
    12661 gtgttggatc ctgtcttggt ctgcaaggaa acgcatgatg tagctgtcag tgagctctgc
    12721 caagagttga ttcgcttttt cccttatgtc agtgtgatta cgcctaatct cccagaagca
    12781 gaattattat ccggtcagga aattaaaacc ttggaagaca tgaaaactgc agcgcagaaa
    12841 ttgcatgatt taggagcgcc agcagtcatt atcaagggag gcaatcgtct tagtcaggac
    12901 aaggctgtgg atgtctttta tgatggacag acctttacta tcctagaaaa tccagttatc
    12961 caaggccaaa atgttggtgc aggttgtacc tttgcctcta gcattgccag tcacttgatt
    13021 aaaggtgata aacttttgcc agcagtagaa agctctaagg ctttcgttta tcgtgctatt
    13081 gcacaagcag atcagtatgg agtaagacaa tatgaagcaa acaaaaacaa ctaaaatcgc
    13141 ccttgtatcc ctattaaccg ccctttctgt ggttctaggt tatttcttaa aaatcccaac
    13201 acctacagga attctaactc ttttagatgc tggtgtcttc tttgcggcct tttactttgg
    13261 tagtcgtgaa ggagcggtag tcggaggact agcaagtttc ttgattgacc tcttatcagg
    13321 ctaccctcag tggatgttct ttagcttggt caaccatggc ttgcagggat ttttcgcagg
    13381 atttaaagga aaaagtcagt ggttaggcct tattttagca actattgcca tggtaggagg
    13441 ctacgccttg ggttctactt tgatgaatga ctgggcagca gccctcccag aaattctacc
    13501 aaattttatg caaaatatgg tagggatgat tgtaggattt attcttagtc aaagtatcaa
    13561 gaagattaag taatactctt cgaaaatctc ttcaaaccac gtcagcttcc atctgcaacc
    13621 tcaaaacact gttttgagca gcctgaggct agctttctag tttgcacttt gattttcatt
    13681 gagtataaag aggttgagta aaaagtcttt caaataagaa aaacgcatag tatcaggtgt
    13741 tgaatgaact gccccccaaa agttagacag aaaaaatcta acttttgggg tgttttatta
    13801 tgaaa
//
LOCUS       DAVDZK010000049        13794 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVDZK010000049 DAVDZK010000000
VERSION     DAVDZK010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13794
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.050"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(<1..977)
                     /locus_tag="VUX16_001876"
     CDS             complement(<1..977)
                     /locus_tag="VUX16_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PavB family fibronectin-binding SSURE repeat
                     adhesin"
                     /protein_id="HET8124781.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVVSGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLPETQGDTVLTEVKPEVVAGNTNSLSTPTEGTEVSEET
                     SPSRLDTLFEKGEETQENPELTDVLKKAVDTADVDGTQASPEDIKKAVDEDVNDTIDV
                     PAAYLEQAKASGPFLAGVNKPLKYELFAGDGMLTRLLLKASDKAPWSDNGVAQNEKIP
                     PVKNLPDGKYYYQVSLNGNTEGKKDQDLLDTLRTNGTNTYEATLTVYEADGDKPDLTK
                     VVKTRNVNITLNGLVTKSDVKSAVENNVKDSIDVPAAYLEQAKGEGPFTA"
     gene            complement(1093..1503)
                     /locus_tag="VUX16_001877"
     CDS             complement(1093..1503)
                     /locus_tag="VUX16_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET8124782.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQENPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            complement(1570..2112)
                     /locus_tag="VUX16_001878"
     CDS             complement(1570..2112)
                     /locus_tag="VUX16_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET8124783.1"
                     /translation="MRKLLSIAISSYNAAAYLHYCVESLVIGGEQVEILIINDGSQDQ
                     TQEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLK
                     ILKTLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKG
                     QYIMMHSLIYRTDLLRASQF"
     gene            complement(2418..3083)
                     /locus_tag="VUX16_001879"
     CDS             complement(2418..3083)
                     /locus_tag="VUX16_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET8124784.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQNMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(3097..4476)
                     /locus_tag="VUX16_001880"
     CDS             complement(3097..4476)
                     /locus_tag="VUX16_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET8124785.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTYFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            4694..4981
                     /locus_tag="VUX16_001881"
     CDS             4694..4981
                     /locus_tag="VUX16_001881"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124786.1"
                     /translation="MKTKASIRELVTGCSKHCFEIVDRTDEVSSKHCFEIVDRTDEVS
                     SKHRFEVADRTDEVSSKHCFEVVDRTDEVSSKHCFEVADRTDEVSNIYTAR"
     gene            complement(5221..5985)
                     /locus_tag="VUX16_001882"
     CDS             complement(5221..5985)
                     /locus_tag="VUX16_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET8124787.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLDEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(6202..6759)
                     /locus_tag="VUX16_001883"
     CDS             complement(6202..6759)
                     /locus_tag="VUX16_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HET8124788.1"
                     /translation="MTSEYQKMIAGEFYRPSDPELRALAQASRQKQAAFNKEENPLKG
                     AEIIKTWFASTGKNLYINTRLMVDYGVNIHLGENFYSNWNLTMLDICPIRIGDNAMIG
                     PNCQFLTPLYPLDPQERNSGIEYGKPITIGDNFWTGGGVIVFPGVTLGNNVVAGAGAV
                     ITKSFGDNVVLAGNPARVIKEIPVK"
     gene            complement(6865..7719)
                     /locus_tag="VUX16_001884"
     CDS             complement(6865..7719)
                     /locus_tag="VUX16_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET8124789.1"
                     /translation="MTYEYQSHIYLAEAVLNVKDLVSQTVFYQQIIGLEILSQTDTEV
                     VLGLGGKALVHLIQAQEGGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEALYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEVLAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSRQFYQTVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLDPRKQVLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            complement(8075..12925)
                     /locus_tag="VUX16_001885"
     CDS             complement(8075..12925)
                     /locus_tag="VUX16_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET8124790.1"
                     /translation="MSRKSIGEKRQSFSMRKLSVGLVSVTLASFFLMSQGIQSVSADN
                     MESPIHYKYMTEGELTDEEKSLLVEALLQLAEESDDTYYLGYIKTKKQDNAGISRTVD
                     GKYSARSDSQPDSTKISDVVHSADSEWSQGQGKVSLQGEASGDDGLSEYTDPVATKGT
                     QEPEHEGEAAVEEELPALEVTTRNRTEIQNIPYTTEEIQDPTLLKNRRKIERQGQAGT
                     RTIQYEDYIVNGNVVETKEVSRTEVAPVNEVVKVGTLVKVKPTVEITNLTKVENKKSI
                     TVSYNLIDTTSAYVSAKTQVFHGDKLVKEVDIENPAKEQVISGLDYYTPYTVKTHLTY
                     NLGENNEENTETSTQDFQLEYKKIEIKDIDSVELYGKENDRYRRYLSLSEAPTDTAKY
                     FVKVKSDRFKEMYLPVKSITENTDGTYKVTVAVDQLVEEGTDGYKDDYTFTVAKSKVE
                     QPGVYTSFKQLVTAMQSNLSGVYTLASDMTADEVSLGDKQTSYLTGAFTGSLIGSDGT
                     KSYAIYDLKKPLFDTLNGATVRDLDIKTVSADSKENVAALAKAANSANINNVAVEGKI
                     SGAKSVAGLVASATNTVIENSSFTGKLIANHQDSNKNDTGGIVGNITGNSSRVNKVRV
                     DALISTNARNNNQTAGGIVGRLENGALISNSVATGEIRNGQGYSRVGGIVGSTWQNGR
                     VNNVVSNVDVGDGYVITGDQYAAADVKNASTSVDNRKADRFATKLSKDQIDAKVADYG
                     ITVTLDDTGQDLKRNLREVDYTRLNKAESERKVAYSNIEKLMPFYNKDLVVHYGNKVA
                     TTDKLYTTELLDVVPMKDDEVVTDINNKKNSINKVMLHFKDNTVEYLDVTFKENFINS
                     QVIEYNVTGKEYIFTPEAFVSDYTAITNNVLSDLQNVTLNSEATKKVLGAANDAALDN
                     LYLDRKFEEVKANIAEHLRKVLAMDKSINTTGDGVVEYVSEKIKNNKEAFMLGLTYMN
                     RWYDINYGKMNTKDLSTYKFDFNGNNETSTLDTIIALGNSGLDNLRASNTVGLYANKL
                     ASVKGEDSVFDFVEAYRKLFLPNKTNNEWFKENTKAYIVEMKSDIAEVREKQESPTAD
                     RKYSLGVYDRISAPSWGHKSMLLPLLTLPEESVYISSNMSTLAFGSYERYRDSVDGVI
                     LSGDALRTYVRNRVDIAAKRHRDHYDIWYNLLDSASKEKLFRSVIVYDGFNVKDETGR
                     TYWARLTDKNIGSIKEFFGPVGKWYEYNSSAGAYANGSLTHFVLDRLLDAYGTSVYTH
                     EMVHNSDSAIYFEGNGRREGLGAELYALGLLQSVDSVNSHILALNTLYKAEKDDLNRL
                     HTYNPVERFDSDEALQSYMHGSYDVMYTLDAMEAKAILAQNNDVKKKWFRKIENYYVR
                     DTRHNKDTHAGNKVRPLTDEEVANLTSLNSLIDNDIINRRSYDDNREYKRNGYYTISM
                     FSPVYAALSNSKGAPGDIMFRKIAYELLAEKGYHKGFLPYVSNQYGAEAFASGSKTFS
                     SWHGRDVALVTDDLVFKKVFNGEYSSWADFKKAMFKQRIDKQDNLKPITIQYELGNPN
                     STKEVTITTAAQMQQLINEAAAKDITNIDRATSHTPASWVHLLKQKIYNAYLRTTDDF
                     RNSIYK"
     gene            complement(13041..13695)
                     /locus_tag="VUX16_001886"
                     /pseudo
     CDS             complement(13041..13695)
                     /locus_tag="VUX16_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT         3949 a         3070 c         2381 g         4394 t
ORIGIN      
        1 gctgtgaatg gaccttcacc cttggcttgt tctaggtagg ctgctggaac atcaatactg
       61 tctttaacgt tgttctcaac tgcagatttg acatcgcttt ttgttacaag accgttcaaa
      121 gtaatattga cattacgtgt cttgacaacc ttagtcaaat caggtttatc tccgtctgct
      181 tcatagacag tcagggtagc ttcataggta tttgtaccat tcgtacgaag tgtatctaat
      241 agatcttgat ccttcttacc ttcagtgtta ccattcaaag atacttgata gtaatactta
      301 ccatcaggta aatttttcac tggtggaatt ttctcgtttt gagcgacacc gttatctgac
      361 catggtgcct tgtcagatgc cttgagcaag agacgagtca acataccatc gcctgcgaaa
      421 agttcgtatt taagcggttt atttacacca gccaagaacg gaccggaagc tttggcttgt
      481 tctaggtagg ctgctggaac atcgatagtg tcattaacat cctcatcgac agctttttta
      541 atatcttctg gacttgcttg tgtcccatcc acatcagccg tatctacagc tttttttaag
      601 acatctgtta gctctggatt ttcttgagtt tcttcacctt tttcaaaaag tgtatccaga
      661 cgggaagggc ttgtttcctc gctcacttca gttccttctg taggtgtaga aagtgagttc
      721 gtatttccag ccacgacctc aggtttcact tcagtcagaa cggtgtctcc ttgagtttct
      781 ggtaagtcac cctctttcgt tcccgatgtc tcttcaggta agacttgacc tggggtcgga
      841 ttgaccacat cggcacgtac agaacttggc tgaccaacta ggacaaagaa gccactaacc
      901 acaacaactg aggcaacacc gacactgaga cggcgaatag accaacgagt atatctttga
      961 tttggattga atttcatagg attctcctta gagtctttct ttatttgatg actctagtat
     1021 aatctcctga aattaaaaag gactaagaaa aagttaaaat ttttcttaaa tccctcttat
     1081 aaaacactta tattaattaa atccataaac agatttggtg atttgataga cgacattgga
     1141 cagtttgcga tctggcaaga cagaatgttt ggtcaaacgg ctcaacatgg tcttgcgaat
     1201 ggcctgaaag acttctggat tttcctgctg aatataggtc cacaattggc gcttttttgc
     1261 cagatgctcc gctgttccag atcggttgag cagggtactg gaaatcaccg tcgtgatttc
     1321 aatatgattc agcagatatt ctcgcatttt gggatgactc acttgggaca aatcaagctg
     1381 gtctaccaag agtcgattga ccttgagttg ctggtcaatg cacttaatca tcacttgctc
     1441 attgacagac tggtcctcac gcccaatcaa ataacgatag aaatcgacag gcagatagta
     1501 catggtcttg acctgctgaa ggggcgtaaa gacaaagaga ttatcgacat aaaaagcatg
     1561 ttcaggcaat tagaactggc tagcacgcaa caaatctgtc cgataaatca gcgagtgcat
     1621 catgatatac tggcctttag agaaatttcc gacctggtcc cagccaaaaa tctgccgaac
     1681 aggcaagact gaatcgtaac tcatactctt cttacgagac tgaccttcct tttcatagac
     1741 aaaattggtc acaaagacat ccacctcttg acccttgctc tcaagttcct gcaaggtttt
     1801 aagaattttc aagtaggcac gaggatccac ccagtcatca ctgtcaacta ctttaaaata
     1861 gcgcccagaa gcctctgcca agccacgatt gaccgcaccg ccatggcctt tattttcctg
     1921 atagatggct ctaacgatgt taggatactt gctagctaaa cactcagcga tttcctgagt
     1981 ctgatcctga gacccgtcat tgataatcaa aatctcaact tgctcaccac caatcactaa
     2041 cgactccaca cagtaatgaa gataggctgc tgcattatag ctagaaatgg cgatagacaa
     2101 taacttccta atctgctcct ttagggactg attttttctt atactcttcg aaaatctctt
     2161 caaaccgcgt caacgtcgcc ttgccgtata gatgttactg acttcgtcag ttctatctgc
     2221 aacctcaaaa cagtgttttg agcagcccgt agctagtttc ctagtttgat ctttgatttt
     2281 cattgagtat tactctctct tgtcacttct ttctatttta ccataaagtc cagcctttga
     2341 agaactttta ctagaagaca aggggcttct gtctctattt gccatcttgg gcatcaaaaa
     2401 agaggggtca tccctcttta cgaattcaat gctactaggg tatccaaata ctggttgttg
     2461 atgactgcca aaatataggt atctgctttc aagaggtcat ctggtccaaa ttcaacatcc
     2521 aatggggaat tttcctgctc tcggaaaccc aaaatattca gattgtattt gccacggagg
     2581 tctaatttac tcagactttg acctgcccaa gactgaggaa ttttcatctc cacgatagac
     2641 acatttttat ccaactgaaa gacatcaaca ctattatgga aaagaatggt ctgtgctaga
     2701 gactgcccca tttcatactc tggcgagata accgagtcag ctccaatctt ttctagcact
     2761 ttcttagcgg tctgactttt gaccttagca ataacagtcg gtacccccaa actcttacag
     2821 tgcataaccg caagcacact cgactccaga ttttcacctg tcgcgactac aacggtatcg
     2881 caggtatcaa tccctgctga tctcaataat tcttcatctg tgatgtcacc aatcactcca
     2941 cgcgccaaaa ctggctcaaa ctgattgatg cgctctgcgt ggtcatcaat agcgataata
     3001 ttcatattct gcttggctag ggcagctagg acactgctcc caaaaattcc caagcccaaa
     3061 attccaatcg tacgatctga catgctcttt cctttcttaa ccaatactaa tatctgcttt
     3121 catatagtga atcatatctt tcttttctgg atggtaatct gccaagctaa caaacaaggt
     3181 caagggacca attcgtccca taaacataag tggcatgata acactgagag ccaatttccc
     3241 aaggtcagga gtcagatttg ccgttacacc aactgtacta agagctgaaa tggtttcaaa
     3301 tatgaggtgg ataaagggag gattgccttt ggctgttatc cctagcagaa tcaatcctat
     3361 caagaagctc atcaaaaaga taataaagac actaaaggat ttttgaaccg ttcgcggcgc
     3421 aatcgttcgt ctcgcaacat tggcatgagg caagcctaga agctcacttc gtgcaaagac
     3481 caagaggaca aaatatgtcg taatcttgag tcccccagct gttcctccag gtgccccacc
     3541 tagaaacatc tgtaagatat aaatcaaaag agtcacagga tgagcctgag tataatctat
     3601 cgtagaaaag ccagctgttc gcatcgtcac tgtttgaaaa aagctaacta aaaccttatc
     3661 ggcaacaggg agattgccaa tcgttccagc attgttccac tcaagaaaga gagtagttgc
     3721 cgttccaaat aacaacaaac ctatagtcaa taatagtaca agcttcgtat gaaagtgcag
     3781 acgtcctttt ttctttcttc ctacatgacc agccaaatca aaccagacca taaaaccaag
     3841 gccgcctgta ataatcaagc ctgcaatcac cagattgacc agtaaatcgg tctgaaaagc
     3901 aaataaactg gtgctcccta aattatcaaa accggcatta cagaaggctg agatcgctag
     3961 aaaaatggaa ctaaaaagac cacgtcccca gccaagttga ggaataaggc gaaaactaag
     4021 caaaatagct cccaagctct caaccaaaaa ggtcgtgaga aaaatagaat agacaaactt
     4081 tctcaaagat cgagtttctc cataactaaa actatcctga atagttgcac ggctacgaag
     4141 actaagcttt tgcttgctct ggatatagaa aaccccaata aaggtcatga gccctagacc
     4201 accgatctga atcaagagca aacagattat ttggccccat atattatagg tgtgagctac
     4261 tggaagggtt gagagacctg tcacacagac tgcagagaca gcagtgaaaa gatgatcaaa
     4321 ataagtcgct cgtgagcttt caacttggac aaagggcaag ctcaaaagaa gagagcctag
     4381 taaaatgacc aaggcaaaac tcaaaaaaat acgacgggct ggcgataatc gagataagcc
     4441 tagctctatt ttttccttag ataatttgaa taacatgttt ccattgtacc ataaaaagct
     4501 cgaaatgact tagataggat aaggcaaaat ccactaacac caagcctaaa aaatgccacc
     4561 tttttattga tagcttaggc aagaacaata cttgatagat gtgactatag gtcaaaaaag
     4621 caagacagga gcttttaacg ccagctactc tatatgcttt tcaggagaaa atttctcttt
     4681 ttgattataa gcaatgaaaa ccaaggcatc gattagagag ctagtcacag gttgctcaaa
     4741 acactgtttt gagattgtgg atagaactga cgaagtcagc tcaaaacact gttttgagat
     4801 tgtggataga actgacgaag tcagctcaaa acaccgtttt gaggttgcag atagaactga
     4861 cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag tcagctcaaa
     4921 acactgtttt gaggttgcag atagaactga cgaagtcagt aacatctata cggcaaggtg
     4981 aagctgacct ggtttgaaaa gattttcgaa gagtatcatt tcatctcact ctaaatctta
     5041 ccaacataaa acgcatagta tcaaagtttt catcacctga tatgatacgt ttttctgatt
     5101 ttaaagattt ttcccaacct caacatgcct aggacaagag gaaggtgacc tcgtttaaac
     5161 atatttttga aaagtatgag ctagacattt tatgataaaa caaatccttt gccagtacaa
     5221 ctaaaggtgg tgaacacttg ctaaactcag ttctagcgcc ttattaaaag cttccgagcc
     5281 ccagtcacga ctgtcgtact ggtccaagtc cgctagagaa tctgctgtga acaacaattc
     5341 accccagaga accccacgca attgagctac tgccgcaaga gcagaacact ccatctccac
     5401 aacagcacag ccttcttcct tacgataagc caccttttca gccgtttctc ggtaaaaacc
     5461 gtctgtcgtc caggtcatga cttcttcata aggaatccct ctgtcttcca aaacttcctc
     5521 aatagcagca atagcctctg gctgcatttc catataacga gaaggtgcca catagtggta
     5581 actggctcct tcatctcgca gagcgcgaac agggactaga aaggcatttt cctctatatc
     5641 agctaggaca ccacaggtcc cagtagagat aatctgctcc acaccatagc caatcaacca
     5701 atccataaac tgggctgctg gagcggagcc aacaggagcc tgagccagac agacctcctc
     5761 acccttgtag ttgatgacat agactggata ggtcttggta gcagaaacga attcgccgac
     5821 acaatccgcc cctacttccc ttgcatagcg gtcaatctcc tcatctaaaa atgcataaac
     5881 acacttcttt ggcaactgca agtccagccc ctcgtgattg ggcatgataa ccgcctgagg
     5941 attgtcatca aactctaaaa taggaatcgc atgtttctga atcatagccc acctcctcta
     6001 attttgtact attgtatcaa aaactgacaa agtgtcaagg aggaagctga tgaactgagg
     6061 agaaaaacat cccacttacg agatgctttg aacttgctta atgaaacaga cttgctaaga
     6121 gatagagtag gtaaatgtga actgggtaaa aaatgatgaa acctacaaaa aagaaacaac
     6181 cccagctgtt cctttttact tctatttaac aggtatttcc ttaatcacgc gcgcaggatt
     6241 gccagctagg acaacgttgt cgccaaaaga tttggtaatt actgcccctg ctcctgcaac
     6301 gacattattt cccagtgtca ctccaggaaa gacaatgacg ccaccaccag tccagaaatt
     6361 atctccgatt gtgatgggct ttccgtactc gatacctgaa ttgcgttcct gtggatctag
     6421 tggatagagg ggtgtcaaaa actgacaatt aggaccaatc atagcattgt ccccgatacg
     6481 aatgggacag atatccagca tggtcaagtt ccaattagaa taaaaatttt cccctagatg
     6541 gatgttgaca ccgtagtcca ccatcaagcg agtgttgatg taaagatttt tcccggttga
     6601 ggcaaaccaa gtcttgatga tttcggctcc cttcaagggg ttctcttcct tgttaaaggc
     6661 ggcctgtttt tggcgagaag cctgagctaa ggctctcagt tctgggtctg atggacggta
     6721 aaactctcct gctatcattt tctggtattc gctagtcata ttattcttct ccttattccc
     6781 tactatcata tcaaattttc cacgtatctg actagaataa ggagcacttt ctacaattga
     6841 tgctctacct tcatcacata ccatctatct agctaaacga atacgggtca cgatgccatc
     6901 tgagtctgtg atttccaatt ggctcgatgt catccatttg attggtgcgt caacttcttg
     6961 tgctcgttgg gcaatcgtta acagttcttc tttatgtgcg acttcgatga catagtaggc
     7021 taaacctggt aggacttgtt tacgcggatc cagacctttt cctccccatt cgttgactgc
     7081 taaatgatga tggtagtccc cagctgcgat ccaactagca ctaggcacac tgaatttatc
     7141 ctcgagccct aacaccgttt gataaaactg tctggacttt cgactatcct tgacagaaag
     7201 atgaatatgc cccattctcg taccctctgc taggataaaa ggctctactc tttcccccaa
     7261 ctcatagata tcctgagccg caaggacttc agtcaccccg ataatacgtc catcttctcg
     7321 aatatcccat gtggaaactg gcttatctcg atagagttca atgccatttc cctccaagtc
     7381 ctctaagtaa agggcctcac tgtaaccgtg atctgcaccg ccaacaagag gaatctgtaa
     7441 atccgtcagg tgcttcaaga catccgccaa agcctttcgt gtcggcaaaa gaatagccag
     7501 atggtaaaga ccataatgtt cccttacttc tccaccctct tgtgcttgaa tcaagtgtac
     7561 caaggctttt cctccaagtc ccagaacgac ctctgtatcc gtttgagata ggatttctaa
     7621 accaataatc tgctgataaa aaactgtttg actgaccaaa tccttcacat ttaaaactgc
     7681 ctctgctaaa taaatgtggc tctggtattc atatgtcata aatatttcct cttttattgt
     7741 aactttaatc attacaacta ttatataact tccctcaaga aagtcaagcc agacaacttg
     7801 aagcatccca ctcagcaaaa aacaatccca gaaaaaatct tctaggattg ttttgtattt
     7861 attttactag actagcaaag ttatttctca aatcaacatt ttctgtggga ttgaaatcca
     7921 ccttgtcacc attggtcgtt gatgagttga agatgattcc tgcaatctgc attcaatcaa
     7981 atctctacat cgatccataa gaaaaaggag tcgatttgtc atctgactcc tcatccttac
     8041 aagaaacact actcaacaat gaaactctac aatcttattt atatatagaa tttctaaagt
     8101 catctgtagt gcgaagatat gcattataga ttttttgttt taataaatgc acccaacttg
     8161 ctggggtatg actcgttgca cgatctatat tagtaatatc tttcgcagcc gcttcattaa
     8221 ttaattgttg catttgtgca gccgttgtta tagttacttc ttttgtacta ttaggattac
     8281 ctaattcgta ttgaattgtt attggtttca gattatcttg tttatctata cgttgtttaa
     8341 acattgcttt tttgaaatca gcccatgatg agtactcacc attgaatact ttcttaaata
     8401 ctaaatcatc tgtcactaaa gcaacatctc ttccatgcca tgatgagaat gttttgcttc
     8461 cgctggcaaa tgcttctgct ccgtactgat tagaaacata aggtaggaat cctttgtgat
     8521 aacctttttc cgcaagtaat tcataagcta tttttctaaa cataatatct ccaggagcac
     8581 ctttcgaatt gcttagcgct gcgtatacag gagagaacat acttatagta tagtagccat
     8641 ttcgtttata ttctctatta tcatcatagc tacgtctatt tatgatgtcg ttgtcgatta
     8701 atgagtttaa cgatgttaag ttagctactt cttcatctgt taatggacgg actttatttc
     8761 ctgcatgtgt atctttatta tgtctagtat cacgaacgta ataattttct atttttctaa
     8821 accatttttt cttaacatca ttattttgag ctaatatcgc ttttgcttcc atcgcatcaa
     8881 gtgtatacat tacatcatat gatccatgca tataactttg aagcgcctca tccgaatcga
     8941 aacgttccac cggattatat gtatgcaatc tattcaaatc atctttttct gctttatata
     9001 acgtatttaa agctaaaata tgagaattta cactatctac agattgcagt aaaccaagtg
     9061 cgtataactc cgctcccaat ccttcacgtc taccatttcc ttcaaagtag attgcagaat
     9121 cagaattatg aaccatttca tgagtataaa ccgacgttcc ataagcatct aataatctat
     9181 ctaacacaaa gtgcgttaaa cttccattcg catacgctcc tgcactacta ttatactcat
     9241 accatttccc aacaggtccg aagaattctt taatagagcc gatgttttta tccgttaacc
     9301 ttgcccaata agttcttcct gtctcatctt ttacattgaa tccatcataa actatcacag
     9361 aacggaaaag tttttctttt gaagcactgt caagaagatt gtaccaaata tcataatggt
     9421 ctctatgcct tttcgctgct atatcaactc tatttcttac ataagttcgt aaagcatctc
     9481 ctgaaagaat aactccatcc acactatcac gatatctttc atacgaaccg aatgcaagtg
     9541 tagacatatt cgatgaaata tacacagatt cttcaggtaa agttagtagt ggtaataaca
     9601 tactcttatg cccccaactt ggtgctgata ttctatcgta aactcctaat gaatattttc
     9661 tatcggctgt tggtgattct tgtttttctc gtacttctgc aatatcagac ttcatttcga
     9721 ctatatatgc ctttgtattt tctttaaacc actcgttatt tgttttgttt ggtaagaaca
     9781 gttttctata cgcttctacg aagtcaaaga ctgaatcttc tccttttacc gatgcaagtt
     9841 tattcgcata taaacctaca gtatttgaag ctctcaggtt atctagtcca ctatttccta
     9901 atgcgataat agtatccaac gttgaagtct cattatttcc gttaaagtca aacttgtacg
     9961 tagataaatc ttttgtattc attttaccat aattaatatc gtaccaacgg ttcatataag
    10021 taagacctag cataaatgct tctttgttat ttttgatttt ctcacttacg tattcaacta
    10081 caccgtctcc tgtagtattg attgatttat ccatcgctaa tacttttctt aggtgttctg
    10141 ctatattagc tttaacttct tcaaattttc tatctaagta taggttatct aaggctgcat
    10201 cattcgctgc tcctagtact tttttagtag cttctgagtt aagtgttaca ttttgcaagt
    10261 cgcttagtac gttattcgtt atcgctgtat agtctgaaac aaatgcttct ggtgtgaata
    10321 tatattcttt tcctgtaaca ttgtattcga ttacttgact gtttatgaag ttttctttga
    10381 atgttacatc taggtattct actgtattat ctttgaaatg taacataact ttatttattg
    10441 aatttttctt attattaata tccgttacta cttcatcatc tttcatcggc acaacgtcta
    10501 acaattctgt agtgtaaagt ttatctgttg tcgctacttt gttaccatag tgaactacta
    10561 ggtctttatt gtagaatggc atcagttttt ctatgttgct ataagctact tttctttcag
    10621 attctgcttt atttagtctt gtataatcaa cttctcttag attacgtttt aaatcttgcc
    10681 cagtatcatc aagagttact gtgattccat aatcagcaac tttcgcgtct atttggtctt
    10741 ttgataattt tgtagcgaat ctgtctgctt ttctattatc aactgatgta cttgcatttt
    10801 tcacatctgc tgctgcgtat tgatcaccgg tgataacata accatctcca acatctacgt
    10861 tactcacaac attatttact cgaccgtttt gccacgtaga tcctactatt cctccgactc
    10921 tagaatatcc ttgaccattt cgtatttctc cagtagcaac cgaattagat atcaatgcac
    10981 cattttctaa tctacctact atccctccag ctgtttggtt attattgcgt gcattagtag
    11041 agattaaggc atctacccta actttattaa ctctcgaact atttcctgtt atattaccta
    11101 ctattcctcc agtatcattt ttattactgt cctggtgatt tgcgataagt ttccctgtaa
    11161 acgagctgtt ttctatcact gtatttgttg cgctcgctac taatcccgca acagatttcg
    11221 cacctgagat ttttccttct actgcaacat tattaatatt cgcgctattc gctgccttcg
    11281 ccagcgctgc gacattttct ttactatcag cagaaacagt tttaatatcc aaatctctaa
    11341 ctgtagcacc atttaatgta tcaaataatg gttttttcaa atcataaatg gcatacgatt
    11401 ttgttccatc agaaccgatc aagctccctg taaatgcacc tgtgagataa cttgtctgct
    11461 tatcgcctaa gctcacctca tctgcggtca tatctgaagc caatgtatag acaccagaca
    11521 gattgctttg catggctgtt accagctgtt taaaggatgt gtaaactcct ggttgctcta
    11581 ctttagattt agctacagta aatgtgtaat catctttgta accgtctgta ccttcttcga
    11641 caagttgatc aacggctacc gtcactttat acgttccatc cgtattttct gtaatagatt
    11701 ttacaggtag gtacatttct ttgaagcgat ctgatttcac ttttacaaag tatttagccg
    11761 tatcagtcgg cgcttcactt agacttaaat atctacgata acgatcattt tctttaccgt
    11821 ataattctac tgaatcaata tctttaatct ctattttctt atactctaat tggaaatctt
    11881 gagttgatgt ttcagtattt tcctcattat tttcacccaa attataagtt aggtgtgttt
    11941 taactgtata cggtgtgtag taatctaaac ctgatattac ttgctctttg gcaggatttt
    12001 ctatatccac ctctttaact agcttgtctc catggaaaac ttgcgttttt gcagaaacat
    12061 atgctgaggt agtgtctatt aagttataac ttacagttat agattttttg ttctcaactt
    12121 ttgttaagtt tgtaatttct actgtaggtt taactttcac aagtgttcct actttaacga
    12181 cttcgttgac cggagctact tcagttcgtg acacttcttt agtttctacg acattaccat
    12241 ttacgatgta gtcttcatat tgaattgtac gtgtccctgc ttgcccttgt cgttcaatct
    12301 tacgacgatt tttcagaagt gttggatcct gaatttcttc tgttgtataa ggaatattct
    12361 ggatttccgt tctatttcgt gtagtgacct ctaaagccgg aagttcttct tctactgccg
    12421 cttcgccctc atgttcgggt tcttgtgtgc cttttgtcgc tacaggatca gtgtactctg
    12481 aaagtccatc atcccctgat gcttcacctt gtaaactaac cttcccctgt ccttggctcc
    12541 attctgaatc agctgaatga actacatctg atatttttgt agagtctggt tgactatcac
    12601 ttcgagcaga gtatttccca tcgactgtcc ttgaaatccc tgcattatcc tgtttcttag
    12661 tcttgatata acccaagtaa taagtatcat ctgattcttc agccagttgt aaaagggcct
    12721 ctaccagcaa ggatttttcc tcgtctgtca attcaccctc ggtcatatac ttataatgaa
    12781 ttggactttc catattatcg gctgataccg attgaatccc ttgactcatc aaaaagaaac
    12841 tagctaaagt aactgatacc aatcccactg acaactttct catcgagaaa ctctggcgtt
    12901 tctcaccaat actttttcgg ctcatattaa cctcgctttt tctacattct ttataccaat
    12961 ctatattttg tagaataaaa gtataaacac aaaaaaatag tatagtatgg aattttctga
    13021 gtacttttca ataattatac tcatctgctt tcaaaaagca ttctagtcca tctccgatta
    13081 acgatggact ttatcacctc cttctccagt ccttgtatga catcttggag ttgattcatg
    13141 acatcttcca aagttcgaaa ggctttattc ttaaatccac gtttacgaat ctctttccac
    13201 acttgttcaa tggggttcat ctctggtgtg tatggaggaa taaaggtaaa gccaatatta
    13261 ctaggatgtt ctggatgtgg cgtaatattt cgccaaccat ggcgcttcaa cagttgatag
    13321 aaggcatcac gtgtgtagga acaacctaac tcctttttat aagcctgaaa taaggcatca
    13381 attgtaacaa attctcctgc ctctgcagcc ttcaaatggc gagcaagaaa aactttctct
    13441 tcctcaaccg tcatatatgc atggttacga ccaccacgag tttcttgaag gagagagtcg
    13501 agtccgaact cctcatattt ttttacattt cgccaaatcg ttgtttgatt acactctaaa
    13561 agctctataa tctctttata agatttaccc catcagacga aatagaacga tttgaaggcg
    13621 tttatgatat ttagctgtac tagagtcttt taaaagtgtt ttgatggctt ggatttcttc
    13681 tttagttgat ttcatattac tattatataa tgctttttga ttttagtcta gtattactta
    13741 tcattataca ataaatcgat agaaatttct attgaaatat acttaaaaat atac
//
LOCUS       DAVDZK010000050        13288 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVDZK010000050 DAVDZK010000000
VERSION     DAVDZK010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.051"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..441
                     /locus_tag="VUX16_001887"
     CDS             <1..441
                     /locus_tag="VUX16_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET8124791.1"
                     /translation="ETGFDTYFYREYGRSLKGQLRRGKVSGRRYQRISLVAGLTNGEL
                     IAPMTYEEMMTSDFFEAWFQKFLLPTLNTPSVIIMDNARFHRMGKLELLCEEFGHKLL
                     PLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            complement(647..2905)
                     /locus_tag="VUX16_001888"
     CDS             complement(647..2905)
                     /locus_tag="VUX16_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET8124792.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGFQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILRGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPIGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADINKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(3129..3359)
                     /locus_tag="VUX16_001889"
     CDS             complement(3129..3359)
                     /locus_tag="VUX16_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HET8124793.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVSYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3549..4232
                     /locus_tag="VUX16_001890"
     CDS             3549..4232
                     /locus_tag="VUX16_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET8124794.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQVGILGVDLSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTIYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KRMGQGDKK"
     gene            4232..4966
                     /locus_tag="VUX16_001891"
     CDS             4232..4966
                     /locus_tag="VUX16_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET8124795.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESKAVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            5120..5977
                     /locus_tag="VUX16_001892"
     CDS             5120..5977
                     /locus_tag="VUX16_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET8124796.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTEKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGFRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALWTLDRK"
     gene            6119..6991
                     /locus_tag="VUX16_001893"
     CDS             6119..6991
                     /locus_tag="VUX16_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET8124797.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLPSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7273..7956
                     /gene="rpiA"
                     /locus_tag="VUX16_001894"
     CDS             7273..7956
                     /gene="rpiA"
                     /locus_tag="VUX16_001894"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET8124798.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7970..9181
                     /locus_tag="VUX16_001895"
     CDS             7970..9181
                     /locus_tag="VUX16_001895"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET8124799.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9183..9725
                     /locus_tag="VUX16_001896"
     CDS             9183..9725
                     /locus_tag="VUX16_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET8124800.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVENLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPLY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9741..10550
                     /locus_tag="VUX16_001897"
     CDS             9741..10550
                     /locus_tag="VUX16_001897"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET8124801.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHAGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            11047..12654
                     /locus_tag="VUX16_001898"
                     /pseudo
     CDS             11047..12654
                     /locus_tag="VUX16_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664829.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            12679..13191
                     /locus_tag="VUX16_001899"
     CDS             12679..13191
                     /locus_tag="VUX16_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET8124802.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
BASE COUNT         3948 a         2411 c         2998 g         3931 t
ORIGIN      
        1 gaaacaggat tcgatactta tttttatcga gaatatggtc gctcattaaa aggtcagtta
       61 agaagaggca aagtatctgg aagaagatat cagaggattt ctttggttgc aggtctaaca
      121 aatggtgagt taatcgctcc aatgacttac gaagagatga tgacgagcga cttttttgaa
      181 gcttggtttc agaaatttct cttaccaaca ttaaacacac catcggttat tattatggat
      241 aatgcaagat tccatagaat ggggaagcta gaacttttat gcgaagagtt tgggcataaa
      301 cttttacctc ttcctcccta ctcacctgag tacaatccta ttgagaaaac atgggctcat
      361 atcaaaaagc acctcaaaaa ggtattacca agttgcaata ccttttacga ggctcttttg
      421 tcctgctctt gtttcaattg actatagcag attgaaataa gatgagaaca aatcgattgg
      481 gaaagtaaaa ttaatttcta taaatgtttt agcaattgtt tcgtactatt tcagattcag
      541 tctactatat atcataatgg acaaagggta agctgtcaag aaattacagt tattttagta
      601 aaaaagaagc agaaaaattt cattttctac tccttttcta taggatttat ttttcttttt
      661 cagaactttt aacttcagct tttttggcag atttaatctg aatgtttccc ttgctagtca
      721 taactgcttt gagatctttt tcgcttggat tttcaaggta gtagtcagtg attgtgtcct
      781 caatatagtc ttgaatagtc cgacgaagtg ggcgtgctcc catttttgga tcataaccta
      841 ggtcaaccaa cttttccttg accttgtcag ttacatccaa acgaatgttg ttgctagaga
      901 ggcgcttgtt aatatctgct agcatgagct cgacaatctg aaggaggtta tccttgctga
      961 gagccttaaa ttcgataatg ccatcaaaac ggttcataaa ctctgggcta aagaagttac
     1021 cgagttcacc gaggacagaa ttggtacgtc cttctctagc agcaccaaat ccaacgctag
     1081 cttcggtctt tcctgtacct gcatttgagg tcatgataat gatggcatcc ttgaagctaa
     1141 cggtgcgtcc ttgcccgtct gtcaaacgac catcgtccaa gacttgaaga aacatgtgca
     1201 taacatctgg gtgagctttt tccacttcat cgagaaggat gagagaatat ggattgtggc
     1261 gaactttttc agttaattga ccagcctcat catagccaac ataacctgga ggagcgccga
     1321 ccaacttagc cacactatgt ttttccatgt attcactcat atcaaagcga atcatactat
     1381 cagcagaacc aaaaagttcg atagccagtt gtttggaaag ttctgtctta ccgacaccag
     1441 ttggcccaac gaagaggaag cttccgattg ggcggttagg ggtaccaagt ccgacacgat
     1501 tacggcgaat agccttggca atcttatcga ctgcatcatc ttggccaata acatgagact
     1561 tgagatcttc ggctagatgg atgagttgag attgttcttt ctctttcaaa tcaccaatag
     1621 ggatattggt tttctgctcg ataatgtgct caatagtttt ctcgctgatg ataggagtat
     1681 cctggtctgt gatctttttc ttttgcattt ccttatactt ggcaatctgg tcgcggaagt
     1741 aggccgcctt ctcaaaatct tcttctcgtg tagcttgaga cttgagattt tcagcctcaa
     1801 tcaagcgctg atcaattact ttaggatcca caaaattcaa ggtcaagttc atcttagaac
     1861 cagcttcatc taggaggtca atggccttgt caggcaagaa gcgatcttgg atgtagcgat
     1921 tggaaagagt tgcagctgct tcaatcgcag catcggtata ttgaacgtgg tggtaatctt
     1981 cgtatttctt ttgaatccct ctgagaatag tgattgtttc gtccaccgtt ggttcatcga
     2041 ctttaacagg ctgcatacga cgctcgaggg cagcatcctt ttcaatgata cggtattcat
     2101 tgagggtagt agcaccgact agttgcagtt ctccacgagc aagggctggc ttgaggatat
     2161 ttcctgcgtc catattacca tcactcgcag aaccagcacc aacaatttca tggatttcat
     2221 cgataaagag gatgatgtct tcacgtttgc gaatttcttc catgagtttt tgcatgcgtt
     2281 cttcaaattg tcctcgaatc cccgttcctt gaactaagct aaccacatcc agacggatga
     2341 cttgtttacc ttggagttta tgtggcacat cgccatcgac aattttctga gctagacctt
     2401 cgacaacggc cgtttttccg acaccaggtt caccgataag gacaggatta ttcttggttc
     2461 tacgattgag aatctcgatg acacggataa tctcatcgtc gcgcccaata acggggtcaa
     2521 tgtctccacg acgggcaatt tcagttacat taataccaaa ttcttccagc aggccttttt
     2581 cttggctagg tggcggagtt tgagcagatc cacgattttg gaaaccataa ccgccgtttc
     2641 caccgtaacc tccacctgat tgggttgggg gaataggagg agtattgcta gaaggtctga
     2701 aattgtttag atcattgaag aaatcaccaa agggatcgaa gtcacgattg ttcagatccg
     2761 tcataccttt gaagaggcta ttgttaggat ctgttttgat aatcttatag cagttttgac
     2821 agaggtcaat ttgtttttgt tttccattga gattggtgta aagatgaatt gttgagtcgt
     2881 taattttaca gttttgacaa agcatacatc tacctcattt ctttctttag cctgacttgt
     2941 ttaaaggtca aaaatagtca aattctatac tctcattata acaggattgg ggtgtaaagc
     3001 aagtaaaaag attgaagctt tgagaagttg ttacaatgaa aatttttgtg aatttggact
     3061 ataaaaaaat cctatttgtg agacaaaaag gattttactt agacatgcag ggacaatccc
     3121 agcttgtttt agtagagaag ttcgtaaatt tccattgcga ttaagtcaat gctatcaaac
     3181 gtatacgttt cgcgatcttc tacgtcacga agggtaaaga ttgggccgtt ttcttcgtcg
     3241 tggctgtacg aaacttctgc aacaacaact ccttcgcgtt caaaattacg ttttaaattt
     3301 ccgccatcgt ttgccattgc ttcaaggcgg ttgatgattc taaccaaatg tgattccatt
     3361 ttgattctcc ttcatttctt atcgttacta ttttaccata aaggaggcca atttgactag
     3421 aaaaaactaa gatttcttgc taattctgct agtttaaaga tttttaaata aattggataa
     3481 aagatttgaa ttttaattca aaacatgtta taatcataca gtattctatt ttagaaagca
     3541 gtgtgactat gaatttttct tttttaccta agtatttacc ttattttaac tatggggctg
     3601 ttgtgacgat tcttatttct atctgtgtta tctttttggg aactattttg ggtgttgtct
     3661 tggcttttgg gcaacgttca aagtttaaac cgcttgtttg gttggccaac ttgtacgttt
     3721 ggattttccg tgggacaccg atgatggttc aaattatgat tgcctttgct cttatgcata
     3781 tcaatgctcc gactattcag gttggaattt taggtgttga tctttctcgt ctgattccag
     3841 ggattttgat tatctctatg aacagtggtg cttatgtttc tgagactgtt cgtgccggaa
     3901 tcaatgcagt tcctaagggg cagttagagg cggcttattc tttagggatt cgtcctaaaa
     3961 atgctatgcg ctatgtaatt ttaccacaag ctatcaaaaa tatcttgcca gctttgggga
     4021 acgaatttat caccattatc aaggacagct ccctcttatc agctatcggt gttatggagt
     4081 tgtggaacgg ggctacaaca gtttctacaa caatctatct acctttaaca ccacttttat
     4141 ttgcagcttt ttattacttg attatgactt ctattttgac agtagccttg aaagcttttg
     4201 aaaaacgtat gggacaagga gataagaaat aatgacagaa accttgataa aaattgaaaa
     4261 tttacataaa tcatttggaa agaatgaagt attgaagggc atcaacctcg agattaaaag
     4321 aggagaagtt gtcgttatca tcggtccttc agggagcggg aaatctacct tgcttcgctc
     4381 tatgaatttg ttggaagaag cgaccaaggg taaggttatc tttgagggag tcgatattac
     4441 ggacaagaag aatgacctct ttgccatgcg tgagaagatg ggcatggttt tccaacaatt
     4501 taacctcttt cctaatatga ctgtgatgga aaatatcacc ttgtcaccta tcaagaccaa
     4561 aggtgagagc aaggctgttg ctgagaagag agcccaagag cttttggaaa aagttggttt
     4621 gccagataag gcagatgctt atccacagag tttgtcaggt ggccagcaac aacggattgc
     4681 cattgcgcgt gggttggcca tggaacctga tgttttgctc tttgacgagc caacttcagc
     4741 actagatcct gagatggttg gagaagttct ggctgttatg caagatctag ccaagtcagg
     4801 aatgaccatg gttatcgtaa cacatgagat gggatttgcc cgtgaggtgg cagatcgtgt
     4861 catctttatg gcagacggtg tggttgttga agacggaaca ccagaacaga tttttgaaca
     4921 aacccaagaa caacggacta aagacttctt gagtaaggtt ttataatcta ttttaaaatt
     4981 tcaagacaag attagtgaaa agctcaacca gagctttttc ttatagtttg aaactatagg
     5041 attgcctagg aaagaagtgt tagagggtgc tggcagtttt tggtataatg gaagatattt
     5101 gaaagaaaag agaagtgata tgacacagat tattgatgga aaagctttag cggccaaatt
     5161 gcaggggcag ttggctgaaa agactgaaaa attaaaggaa gaaacaggtc tagtgcctgg
     5221 tttggtagtg attttggttg gggacaatcc agccagccaa gtctacgttc gcaacaagga
     5281 gaggtcagct cttgcagctg gtttccgtag cgaagtagtg cgagttccag agaccattac
     5341 gcaagaggaa ttgttagacc tgattgctaa atataatcag gatcctgctt ggcatgggat
     5401 tttggtccag ttgccattac caaaacacat tgatgaagaa gcggttctat tggctattga
     5461 cccagaaaag gatgtggatg gtttccatcc cctaaacatg gggcgtctct ggtctggtca
     5521 tccagtcatg attccatcaa cacctgcagg aattatggaa atgtttcatg aatatgggat
     5581 tgacttggaa ggtaaaaatg cggtcgtcat cggccgctcc aatatcgttg gaaagcccat
     5641 ggcccagctt cttttggcca aaaatgcgac agtaaccttg actcactcac ggactcataa
     5701 tcttgccaag gtggctgcta aggcagatat tcttgtggtt gcaattggtc gtgctaagtt
     5761 tgtgactgct gactttgtga aaccaggtgc ggtagtcatt gacgttggaa tgaaccgcga
     5821 tgaaaatggt aagctctgtg gggatgtgga ttatgaggcg gttgccccac ttgctagcca
     5881 tattacgcca gttcctggag gtgtaggtcc tatgaccatt actatgctga tggagcaaac
     5941 ttatcaggcg gcactttgga cattggatag aaaataagag aaacattcga ttaatagagt
     6001 gtattttcta tagctatatc taaaatggca gaaatgaata ttaaatttta gatataagat
     6061 tacaaaagga ggtctgcgcc tcctttttgt tgtataataa aagtgagagg aaaaaaggat
     6121 gaaagtgatt aatcaaacct tactagaaaa agttattatt gaacgttctc gttcaagtca
     6181 taaaggagat tatggtcgtc tgctgctgct tggtggtact tatccttatg gaggtgccat
     6241 catcatggct gctttagcag ctgtaaaaag cggtgcagga ttggtgaccg ttggaacgga
     6301 cagggaaaat atcccggctc tgcacagcca tttacctgag cctatggcct tttctcttca
     6361 agaccagcaa ttgttaaaag agcaattgga gaaggcagaa gttgtcttgc tggggcctgg
     6421 tttacgagac gatgcttctg gagaaaatct agtaaaacag gtctttgtta atttaagcca
     6481 aaatcagatt ttgattgtag acggaggtgc cttgaccatt cttgctagga caagtttgtc
     6541 atttccctca agccagctta tcctaactcc tcaccaaaaa gaatgggaaa aattatctgg
     6601 aattacgatt gaaaagcaaa aggaagatgc aacggctagt gttctgcctt ctttccctca
     6661 aggaacaatt ttggtggaga aaggcccagc tactcgtatt tgggaagttg gccaatctga
     6721 ttattaccag ttacaggttg gtggtcctta tcaggcgact gggggaatgg gagatactct
     6781 ggctgggatg atcgcaggat ttgtaggcca attccgacag gccagtctct acgagcgtgt
     6841 ggcagtagcg acccatcttc attcagccat agctcaagaa ctatctcaag aaaattatgt
     6901 ggtcttaccg acggaaatca gcaggtatct tcccaaaata atgaaaatta tttgtcaaca
     6961 agagagggta agcaaagata aacttgttta aaatagacag ataaatctac ttccttctct
     7021 taatttatga ttcttgaaat gcacctgctt taaggctaaa ctagacgtat caaagttaag
     7081 agtttgtttt tgtaactgga aagagatgaa caaatcaaat acataaaaga taaactcatt
     7141 tttattcgtt tggtaaaaat aaaatacata tttttaaaga aagattgatg aaaaatgtag
     7201 atttgatgtt tttacttgaa taaaaagcgg tttcatagta aaataagaac tgagaatgat
     7261 ggaggtaaat cggtggaaaa tctgaagaaa atggcaggta tcaaggctgc tgagttcgtg
     7321 agcgatggaa tggtcgttgg acttggaaca ggctcgactg cctattattt tgtcgaagaa
     7381 atcggtcgtc gtatcaagga agaaggattg cagattacag ctgtaacaac ttctagtgtg
     7441 accactaaac aggcagaagg ccttaatatc ccgctcaagt ctattgacca agtagacttt
     7501 gtcgatgtga cggttgatgg cgcggatgaa gtggatagtc agtttaatgg aattaaaggc
     7561 ggtggtggtg cccttctcat ggaaaaggtg gtcgcaacac catcaaaaga atacatttgg
     7621 gtggtggatg aaagcaagct ggtcgaaaaa ctaggtgctt ttaaattgcc agtagaagtg
     7681 gttcagtatg gtgcagagca ggtctttcgt cattttgaac gagctggcta caaaccaagt
     7741 ttccgtgaaa aagacggcca acgttttgtg acggatatgc agaattttat cattgacctc
     7801 gccttggatg tcattgaaaa tccaattgct tttggacaag aattggacca tgtcgttggt
     7861 gttgtggagc atggtttatt caatcaaatg gtggataagg taatcgttgc tggacgagat
     7921 ggagttcaga tttcaacttc aaaaaaagga aaatagaagg gggcataaga tgtctaaatt
     7981 taatcgtatt catttggtgg tactggattc tgtaggaatc ggtgcagcac cagatgctaa
     8041 taactttgtc aatgcagggg ttccagatgg agcttctgac acactgggac acatttcaaa
     8101 aacagttggt ttgaatgtcc caaacatggc taaaataggt cttggaaata ttcctcgtga
     8161 aactcctctt aagactgtag cagctgaaag caatccaact ggatatgcaa caaaattaga
     8221 ggaagtatct cttggtaagg atactatgac tggacactgg gaaatcatgg gactcaacat
     8281 tactgagcct ttcgatactt tctggaacgg attcccagaa gaaatcctga caaaaatcga
     8341 agaattctca ggacgcaagg ttattcgtga agccaacaaa ccttattcag gaacggctgt
     8401 tatcgatgat tttggaccac gtcagatgga aactggagag ttgattatct atacttcagc
     8461 tgaccctgtt ttgcagattg ctgcccacga agacattatt cctttggatg aattgtaccg
     8521 tatctgtgaa tacgctcgtt cgattaccct tgagcgtcct gcccttcttg gtcgcatcat
     8581 tgctcgccct tatgtaggtg aaccaggtaa cttcactcgt acggcaaacc gtcgtgactt
     8641 ggctgtatct ccattttccc caactgtttt ggataaattg aatgaggctg gtatcgatac
     8701 ttatgctgtg ggtaaaatca acgatatctt taacggtgct ggtatcaacc atgacatggg
     8761 tcacaacaag tcaaatagtc atggaattga tacactattg aagactatgg gacttgctga
     8821 gtttgaaaaa ggattctcat tcacaaacct agttgacttt gatgcccttt acggccatcg
     8881 tcgtaatgct cacggttacc gtgattgctt gcatgagttt gatgaacgct tacctgaaat
     8941 tatcgcagct atgagagaga atgaccttct cttgattact gcggaccatg gaaatgaccc
     9001 aacgtatgca ggaacggatc acactcggga atatattcca ttgttggcct atagccctgc
     9061 ctttaaagga aatggtctca ttccagtagg acattttgca gatatttcag cgactgttgc
     9121 cgataacttt ggtgtggaaa ctgctatgat tggggaaagt ttcttagata aattggtata
     9181 agatgacgcg ctatgctttg ctggtgagag gtatcaatgt tggtggtaag aataaggtcg
     9241 tcatggcgga gcttcgtcaa gaattgacaa acttaggact ggaaaaggtt gagagctaca
     9301 tcaacagtgg caatattttc tttacttcga tagattccaa agcccaattg gttgaaaagc
     9361 tagagacttt ctttgcagtc cattatccat ttattcagag cttttcttta ctgagtctag
     9421 aggactttga ggcggaactt gaaaatctac cagcttggtg gagcagagac ttggcacgaa
     9481 aagattttct cttttacact gagggtttgg atgtggacca agtcatcgcg acagttgaaa
     9541 atttagagct gaaagatgaa gtgctttatt ttggaaaact tgggattttc tgggggaaat
     9601 tttctgaaga atcctattct aagactgcct atcataagta cttgctgaag gtgcctttat
     9661 accgccacat tactattcgt aatgctaaaa cctttgacaa aattggtcaa atgctaaaaa
     9721 aataataaag gagacacaca atgacatttt taaacaaaat ccatgaaact gctactttcc
     9781 tgaaagaaaa gggaattgca gcccctgagt tcggtctaat ccttgggtca ggacttggag
     9841 aattggcaga agaaatcgaa aatccagttg tagtagacta tgctgagatt ccaaactggg
     9901 gccgttcaac agtagtcggt catgctggta aattggtata tggtgaactg gcaggtcgca
     9961 aggtcttggc tcttcaaggt cgtttccatt tctatgaagg gaatcctctg gaagtggtga
    10021 ctttcccagt tcgtgtgatg aaagttcttg gatgtgaagg tgttattgta accaatgcag
    10081 ctggcggtat cggatttggt cctggtacct tgatggctat ctcagaccat atcaacatga
    10141 cggggcaaaa tccattgatg ggtgaaaact tggatgactt tggcccacgt ttcccagata
    10201 tgtctagggc ctacacacca gaataccgtg ccactgccca tgaagtggct aaaaaactta
    10261 atatcaagct tgatgaaggt gtctatatcg gagttactgg tccgacttat gaaacaccag
    10321 cagaaattcg ttcctataag acactgggag cagatgcagt tggtatgtct acggttcctg
    10381 aagttatcgt ggcagcccac gctggcttga aagttctggg aatttcatgt atcactaact
    10441 ttgcggctgg tttccaagaa gaactcaatc acgaagaagt tgtagaagtg actgaacgtg
    10501 ttaaaggtga tttcaaaggc ttgcttaaag cgattcttgc tgaattgtaa gaaaaaagat
    10561 ttaaaagggg gagtgcctct gttttttcag gattgactgc ctatccggat taaagaagaa
    10621 acagaggaat actatgagct tcttcctgct cttataactg aaagaagcgg aagaataggt
    10681 atgtctgatc tgatagccag cattgtgaaa gacaagattc taggatacta gcattagctt
    10741 cctagccaag cagactagta tgataaggag agatgagaat gaattgactt tctgaatttc
    10801 tcagtcttat catatatagc acaatgagat ttcgcttgag tctgcttgta aataaacgaa
    10861 aagaaagata agaaataatg aaaattggtc aacgaattat gcgctttggc ataaaaaatt
    10921 aagtatcgga gttgtatctg ttgtagtcgg ctttgatttc tagctccagc tggaatttca
    10981 gccaatgaag taaagttaga tgtaacatct gaagtggtaa taggtgtgct agattctaag
    11041 gaggaattga aagagtcaga aaatgatgct ccaaaactag aaactcctct tagagaggag
    11101 ccaagactag ctcctcaaac gcttccggaa gcaagtgaag ttcttgaaaa caaaagggaa
    11161 gagtcaaaag tagagataac agagccagct caagactcac ctattcttgc tcctgtagaa
    11221 gaaactaaag aagaagctgt gacagaaaaa ccaacaaata ctcgttctct aactgcagaa
    11281 gatttggtga agatttccaa aggggaattg catttagaaa atgatttgat tgatgaatct
    11341 ttctatggtg aaaaagctct tgatttggaa ggggatgatg accaggatgg catcaaaaac
    11401 aaagatggta aggattatct aggatataac agtcatccct tgctagcaga cagtgatggg
    11461 gatggtttgg cagatgggga agatgataat aagaaagaat ggtatgtcac agaccgtgat
    11521 tctcttctct ttatggagtt agcttatcga gacgatgatt atattgagaa aattttagat
    11581 cataagaatc ttttccctag tctctatctt gaccgtcaag aacacaaact catgcacaat
    11641 gaattggctc ctttctagaa gatgaaaaaa gcctactata cagatagtgg cttggatgct
    11701 ttcttatttg agaccaagag cgaccttcct tatctcaaag atgaaacggt gcacatgttg
    11761 gctattcgtg gaacgcgagt taatgacgcc aaggacttga gtgcagattt ggttttatta
    11821 ggtggaaata aactagctca agcggatgat atccgcaagg ttgttgggga attagccaag
    11881 gatataagta ttactaagtt gtatatgaca ggtcattctc ttggatgcta cctagctcag
    11941 attgcagagg ttgaagctta ccaaaaatat cctgattttt ataaccatgt attgaggaaa
    12001 gtgacaactt tcagtgctcc taaagtgatt acttccagaa ctatttggaa tgctaagaat
    12061 ggtttctggg atgttggttt ggaaagtcgt aaattagctg ttagtggaaa aattaagcat
    12121 tatgtggttg ataatgacaa tgttgtgact cccttgattc ataataatcg tgatattgtt
    12181 acatttacag gtaattcacg ctttaaacac cgttctcgtg gctattttga aagtccaatg
    12241 aatgatattc ctaactttaa tattggtaaa caagctacct tggataaaca tggttatcgt
    12301 gatccgaaat tggataaagt gcgattcttt aagaaacagg ctctgcctcg atcttctagt
    12361 caaccaagcg ctgaaccaat ggaaaatatt gccttaggaa aacaggttac tcaaagttcg
    12421 acagctttcg gaggagatgc tagaagagct gtggatggca aagtcgatgg taactatggt
    12481 cacaattctg tcactcatac aaacttccaa tctaagcctt ggtggcaagt agatttggct
    12541 aaagaagaaa ccattcgcca aatcaatatt tacaaccgaa cagacactgc ccaggataga
    12601 ttggcaaact ttgatgtcat tcttttagac agttctggta aagaaattga gtgaaaacgt
    12661 ataatatctc ctaaagatgt gtcagcacaa attacgatta accataaaaa agcgcgctat
    12721 gttcggattg agctagaagg ctataatgcc ctcagtcttg cagaagttga agttttccgc
    12781 tttatagcta cgaatgctga aacggcgaca caagtttcta agccagttca accaatcagt
    12841 cagactcctg tgaaagataa aacattgaca attcaacaca gtggagctta cattgcccgc
    12901 tactccataa cttgggaaga agttccagta gataaagatg gaaaccaagt tgttcgtagt
    12961 cattcttggg aaggaaacgg tcgcaaccag actgcaggtt ttgtcctcaa cctcccaatc
    13021 aaagaaaata tgagaaatct gcgagttaag attgagaaaa agacgggcct actatggaat
    13081 agatggcaaa caatctatga aaacagacca attttagctc aaccccaccg taaaattacc
    13141 cattggggta cgacattgaa ttccaaggtg agtgacgatg atgtcttgta atctgatggt
    13201 agaatgacag ttagtttgtc tagtttataa gaaagtacta cctgagcttg aatagaactc
    13261 aggtagctct ctatgaaaga acaaaatt
//
LOCUS       DAVDZK010000051        12894 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVDZK010000051 DAVDZK010000000
VERSION     DAVDZK010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12894
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.052"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(<1..2669)
                     /locus_tag="VUX16_001900"
     CDS             complement(<1..2669)
                     /locus_tag="VUX16_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET8124803.1"
                     /translation="MDQEKGRPKTIGHRLDRKLEKVRKNYRTVQQDSAKQLTKLQSQT
                     HSKRQLVKKSRSQFRASKNKVKKIQKEYKRIQKEYKNIQKQGRNLGKEGKSLRPEEIK
                     KQVFLKQELDRNNKKRVFLKQELDKAKLEKKTSKRTFKVAQEANGGSRKKKFLRAAKQ
                     SVERVANQQASSVAHQDDTLSDIARTKYRYQDIQIQGKRIKTIGKYSGKLGQGMVKSS
                     YSLGNRVYNKAKGRGFTQTPREFSWEGKLSRRIQDYKKRLATSKTGKVAKKARKFYRV
                     GSKPLKVIIKNPFSLKAYLIAFGLLLFLAILGIGSSGITRQDEFDMNDTWLYLSKLDR
                     EKSNDKVDYWTKIDDPLLYLNYKYDDISDKLRIDGNNYFSQQNRGKLYLDTLWKNLNG
                     DKDNLKTMEELYTKNNLYKLDKDELEEYKELLEIARDSGKYMLLQELDNPFYTEEQPE
                     SQAPLQIIERFGYKSKTEVFNGSVLQVSGGQSLLAVLDGKVEVKGSDIEISDQDSKFL
                     YKNVDTIRYKTGDHVKAGDIIGKVAPEGNQTVYYQKLEPDRLNKKDKDGNVEKSWTYV
                     NVGFYFQRVEYTQATSVVSNIETSGEKGRRARAFADAIKKNIPEATDEGIAAVLGGFD
                     IESSITFKRYETDYLTNNQFDKVAKEPTAENLVGNWGAFQAMYPTLPLNERGYLVNGL
                     HYIGIGIGQFTGPRALALWNFAKSVNGDIWSAEVQTKFLLEEDDPTRRAAFRRIVTST
                     GSVEALAEDFLNAWLGVPGNKLLERQNAARQWLNFLKNKGGGSTGVSSKQVPAEYKDK
                     LPYGLPTDQALLEGQGYSGNAYELGNCTWYVYNRFAQIGVGIHPYLGNANQWVDSGQA
                     QGYDISTTPKPGSAAVFMNGVAGASPIYGHVAF"
     gene            complement(2680..5043)
                     /locus_tag="VUX16_001901"
     CDS             complement(2680..5043)
                     /locus_tag="VUX16_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HET8124804.1"
                     /translation="MSLFKSKREKLEKAEKKKIDRLRRQMKPTTQNTINYTLLHEDGL
                     MHIAREKYSRSFMLGDASYSTAQQDEKESIIDTTMDALNSLDEGSNYQLLVINRRVSD
                     NSLQNILYEETNDGFDDYREELNEMIKERFTTHANNFEVHKYVTISTNADDRKQAQLI
                     LQDIGVSLGTQFQESDITFRDMNGLDRLKVFSELLRDNPYVNFDYKEIALTGLFTKSF
                     IAPNRIEFQEKRMIIDDRWCKVLYARRYPNWMSDRLIRDLTTLGLELAITIHAEPYEN
                     VEILEKIDDAETDAEIGKLRSKRKAAQSGIFDDAVVAGRDQEISEATKKWRDEITEYD
                     QKIFSGLIAVYFKADNQEELQRNEQKIKRAGRKLGVEFEDLYYYQEEALNTVLPIGEC
                     FLNVKKNFMRKMTTANIATQVPFTNVDLKSESSLARYYGQNQLSNNIITLDRKRDLNT
                     GSGVVLGSSGSGKSTTIKGGEVIPTLLKYPEDRVIIVDPEDEYSDIGRAFGAQMVDIS
                     IGSKTHINLLDLPDLDRLDDEDDDPIGDKANLLMGLFESILSEVTDAQIGIIDRVTGV
                     TYERYLTENFTPTLKEWHQVLKEQPEPEAQDLALAVETYTTGSQDIFAHNTNVDLNHR
                     FVIFNLKKLSHKLKPFALMVIQDYIWNQIVENQGKCTTWVYFDEMQILFKNKAQADFF
                     TTLYSRIRKYGAIPTGITQNVETLAAVEEGRKLLSNSEFMILLKQKPQDLAILKEIVN
                     LTDKQIRYLARPKAKGTGLIVAGPVVVPFENPIPKNTKLYNLVATDA"
     gene            complement(4985..5359)
                     /locus_tag="VUX16_001902"
     CDS             complement(4985..5359)
                     /locus_tag="VUX16_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124805.1"
                     /translation="MKKIGSEFLREFETEDKPILFGLTSRMLVLYLCLIIAVSGTTAS
                     YFFGLPDWYIYLWDALFVVPGGMYGTGMTKRMRIKEKINFFFRIQQRTYEIEFGKVGM
                     YTKDEFIQKQKRKTRKSRKEKN"
     gene            complement(5458..5961)
                     /locus_tag="VUX16_001903"
     CDS             complement(5458..5961)
                     /locus_tag="VUX16_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124806.1"
                     /translation="METLKEIGNKQFNDLQKKHGTRELKDKITSLEQEITRLSWFAYE
                     HELLSEPLLEWILDGKVKISEIPRAVRMSSYGDELYIYAWRYAEAKQDAFYGMRILTL
                     LQEDITYCAIADSISQTEYVYRLEQWIKYMDRGKMVFKGDENFERYFQEQKTANRSLF
                     DTEGVGI"
     gene            complement(6049..6798)
                     /locus_tag="VUX16_001904"
     CDS             complement(6049..6798)
                     /locus_tag="VUX16_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET8124807.1"
                     /translation="MNLDIRELTSSLSSYGSATNQAVNMMADAVRPIGYILLGLFFWF
                     EMASWSQMVKSRGGSLTQKIWLEALMKYLFAFIMISASSQICDAILELLNIIVKVIAH
                     VTPTVKATIDSNISGGKGIVEKTIITFVGKAVSGVANVILGIIVFLRYLDLYMLKALA
                     PLLVAFFMMDSLRSVTINFLKYFAASALIGVILIIVSVVYDSIVAADILKVTTGSSDS
                     WGTAFASIAKGVIYIFVMVGSSRKAKQLLGV"
     gene            complement(6808..7035)
                     /locus_tag="VUX16_001905"
     CDS             complement(6808..7035)
                     /locus_tag="VUX16_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124808.1"
                     /translation="MEIITKIITGLGVVGTITGLIWIWNGAVDYIQGRKNKDKQRQDD
                     GSDSMINGAFLAVASAGIAAAVVAALSQLKF"
     gene            complement(7118..7537)
                     /locus_tag="VUX16_001906"
     CDS             complement(7118..7537)
                     /locus_tag="VUX16_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124809.1"
                     /translation="MKFGSDFSWLWVAIIRIFTAPFYIVLWCINVVKSTIGMFILWVI
                     AKICITIVLIGGMAIIHHLFNFPSENIIDNIFGWYTPHILGMSHDSLITAGQVVDAPK
                     GGGLFFPYPNFEVPIIIGLSILVATVRTIYREEFEEL"
     gene            complement(7609..12054)
                     /locus_tag="VUX16_001907"
     CDS             complement(7609..12054)
                     /locus_tag="VUX16_001907"
                     /inference="COORDINATES: protein motif:HMM:TIGR04228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET8124810.1"
                     /translation="MNRINQKNASIRAENEKNQRENQAEIDRINQENAEIRKRNEAKR
                     GAYESSLTDYTKKLATIKAERDAIQTSKPLFGSETGFKVYGGYNSAGRGSLDYYNDFT
                     VVPDDNLPVESMRGFLGYHADTYVTGGAGTRVSKDSTETYDIIKSPTFGDTFYIHNIG
                     TLTDGRKIMAKVMVSDLGDYQGEVRNGVPVTDSDIYLKGGDGGSFYFVYNNHTRLEMV
                     FDFYIEGTTTPVSLLIGTVITDVDWGQGSNLSYGSSGRGMVLNPSGSGLDFDGRVMKG
                     VENGVNDTSDIPKASFASVGYGSSLTYLHTSSPGSTEGRTPAEWDAENLSGNVQNVVF
                     TILGEGAELKSIPPVNPPRKPTYEVETTPPNSPTGKPEEVLPPKPEEIKEKEIPSLVS
                     PPTVRVRYARLQAMPDLEKFVKNSSGESIDKSYVPKLSTVQWELTTKPLPANREAITD
                     FEIVDALPSGFVLDVEASKKISSDFELTYDESSHVVRMKGLESLKSKLNQDLSKEVQV
                     PAPILVGKVTNDGATYKNNFQLKINNKYASYSNIVQISTPGKPNDPDNPNNNFIQPLK
                     HNYNKDKVIIDGKPVLVGSTNYYHITLDYDQYKGMKADSSTILKGFGAIDDYPEEAVT
                     INQSDIRYIDSEGKEVAGISVYQYDSIDAVDNDKVKAFLASSEIKPKGAFQVFLVDDP
                     EAYFNQYIKSGKSVTIIDPMVTKEELRNTGKSFENTAYQVDFGNGYQTDTVVNNVPTV
                     KPTKKNLNKAGVNIDGKQVLAGSVNYYKVTADYSQYKGIEADKDRIGKGFYIVDDYPE
                     EAVTINQDGVQVTDSKGQVVKGLKMALYDSLDKAPSGVQESLESSHFTPKGAIQVFEA
                     ENPEEFYKTYVQAGEVLTITNPMTVKKELGQTGGKYENTAYQLDFGSGYQTDKVENNV
                     PTAKPTKKNLNKAGVNIDGKQVLAGSVNYYKVTADYSQYKGIEADKDRIGKGFYIVDD
                     YPEEAVTINQDGVQVTDSKGQVVKGLKMALYDSLDKAPSGVQEALKSSHFTPKGAIQV
                     FEAENPEEFYKTYVQAGEVLTITNPMTVKKELGQTGGKYENTAYQLDFGSAYITDTVV
                     NNVPTVKPTKKNLNKAGVNIDGKQVLADSVNYYKVTADYSQYKGIEADKDRIGKGFYI
                     VDDYPEEAVTINQDGVQVTDSKGQVVKDLKMSLYESLAKAPSGVQEALKSSHFTPKGA
                     IQVFEAENPEEFYKTYVQAGEVLTITNPMTVKKELGQTGGKYENTAYQIDFGMDYVTE
                     TVVNNVPKIEPKKDVVIDHLSKESLDGKEVKLNQTFNYKLVGSLVPKDRSEQLFEYKF
                     SDDYDETHDDYQSVYKVFAAVDFETSDGQKFKAGDELTKFTSQVVDKAKGKVDISFDD
                     ALLKSILETSEFQAEVYLQMTRIQSGAVENTYYHTVNGVEVASNTVVTQTPEEPKTPE
                     EHPQQPERSLPSTGEQASAELLLAGLAMGGAASGLLYSKRKKKEA"
     gene            complement(12072..12578)
                     /locus_tag="VUX16_001908"
     CDS             complement(12072..12578)
                     /locus_tag="VUX16_001908"
                     /inference="COORDINATES: protein motif:HMM:NF037874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124811.1"
                     /translation="MHKARETKTYGSIRKSKIYGTCGVILGLAALSMISPVIADERTE
                     NKATNAPYAQTSPSSISTENQGKSEEKTGTLEVSISHSSLDETIRKAQEAGLKVEFDS
                     VVDKGTASTASELEKSKRKSRVIIAHKQIVLRKLLKNIVKIKDKIKRTERKSKMKILR
                     RRNNIKRI"
     gene            complement(12724..>12894)
                     /locus_tag="VUX16_001909"
     CDS             complement(12724..>12894)
                     /locus_tag="VUX16_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface protein"
                     /protein_id="HET8124812.1"
                     /translation="DSSYKAWYYLKSDGSYLRDQWFKDGSAWYYLKADGKMAQNETIG
                     AYYLDYSGKWIS"
BASE COUNT         3650 a         2891 c         2072 g         4281 t
ORIGIN      
        1 cagaaagcaa cgtgaccata gattggcgat gccccagcta caccattcat gaatacagct
       61 gcagaacctg gtttaggagt cgttgaaatg tcatatcctt gcgcttggcc actatcaacc
      121 cactgattgg catttcctag atagggatga ataccaactc caatttgagc aaagcgatta
      181 tagacatacc aagtacaatt ccctagttca taagcgttac ctgaatagcc ttgtccttct
      241 aaaagtgctt gatcggtagg tagtccataa ggtagcttat ctttatattc tgctggaact
      301 tgcttgctag aaacacctgt cgaacctcct cctttatttt ttaagaaatt caaccattga
      361 cgagctgcat tttgtcgttc taagagctta ttacctggta ctcccaacca agcgttcaag
      421 aagtcctctg caagagcttc tacggaaccc gtcgatgtca caattcttct gaatgctgca
      481 cgtctagttg gatcatcttc ctccagaaga aattttgttt ggacttctgc agaccaaata
      541 tctccattca ctgattttgc aaaattccac aatgcaagag cacgagggcc agtaaattga
      601 ccaatcccaa tcccgatata gtgcaaacca ttgactagat accctctttc atttagaggc
      661 aaagtagggt acatagcttg aaaggctccc cagttgccaa ctaaattttc tgcagttggt
      721 tctttagcaa ctttatcaaa ctgattatta gttagatagt ctgtttcata gcgtttaaaa
      781 gtgatggaac tctcaatatc aaatcctccc aaaacggctg caatcccttc atcagttgcc
      841 tccggtatat tctttttaat cgcatccgca aaagctcttg cacgtcttcc tttctctcca
      901 gatgtttcaa tattactgac aacagacgtt gcttgagtgt actctacacg ctggaagtaa
      961 aaaccgacat tgacataagt ccaactcttt tcaacattac catctttgtc tttcttattt
     1021 aatcgatcag gttctagctt ttgataataa acggtttgat ttccttcagg tgctaccttt
     1081 ccaataatat ctccagcttt gacgtgatca cctgttttat agcgaatcgt atctacgttc
     1141 ttatacagaa acttggaatc ctgatcacta atttctatgt cactcccctt aacttcaact
     1201 ttcccatcta aaacagctaa cagagactga cctcctgaaa cctgcaaaac agatccatta
     1261 aaaacttccg tcttcgattt atatccaaaa cgctcaataa tctgaagagg tgcctgcgat
     1321 tcaggttgtt cttctgtata aaatggatta tctagttctt gaagcaacat atattttcca
     1381 ctatctctag caatttctaa gagctcttta tactcctcta actcgtcctt atcaagctta
     1441 tagagattat ttttggtata aagctcttcc atcgttttaa gattgtcttt atccccattc
     1501 aaattcttcc ataaggtatc taagtaaagt tttccacgat tctgttgtga aaaatagtta
     1561 ttcccgtcta tacgaagctt atctgaaata tcatcatact tataattcaa gtataaaagc
     1621 ggatcgtcaa tttttgtcca ataatctacc ttgtcattcg atttttcacg atccaatttt
     1681 gaaagataca accaggtatc attcatatca aattcatctt gacgggtaat tcctgaacta
     1741 ccgataccaa gtatagccag aaacaaaagc agaccaaatg caatcagata agcctttaag
     1801 ctaaatggat ttttgataat aactttaagc ggtttagaac ctacacggta aaacttccta
     1861 gccttcttag ccactttccc tgttttagaa gtagccaagc gtttcttata atcctgaata
     1921 cgacgagaga gttttccttc ccaagaaaat tctcttggag tttgagtgaa gcccctaccc
     1981 ttagccttat tgtagactct atttccaagg ctatagctcg atttaaccat tccttggcca
     2041 agtttaccgc tatacttccc aatcgttttg attcgtttcc cttgaatctg aatatcctga
     2101 taccgatatt tagttcgtgc tatatctgat agtgtatcat cctgatgcgc aacagagcta
     2161 gcctgttgat tagcaactcg ttctacagat tgttttgccg cacgaagaaa cttcttcttg
     2221 cgtgaaccac cattagcctc ttgagcgact ttaaaagttc ttttagaagt ttttttctcc
     2281 agtttcgcct tatctaattc ctgcttaagg aagacccgct ttttattgtt cctatctaat
     2341 tcctgcttaa ggaagacctg ctttttaatt tcctctggac gaagtgactt tccttctttt
     2401 ccaagatttc ttccttgttt ctggatattc ttgtactctt tttggattct cttatactct
     2461 ttttgtattt tcttgacctt gttcttagaa gctcgaaatt ggcttcgact cttctttacc
     2521 aactgacgtt tagagtgagt ctgagattgt aacttcgtaa gttgttttgc gctatcttgt
     2581 tgaaccgttc ggtaattctt acgaactttt tctagctttc gatctaacct atgaccgatt
     2641 gtttttggtc tgcctttctc ctgatccata gtgagacccc taagcgtctg ttgcgactaa
     2701 gttatacaac ttagtattct ttggtattgg attttcaaat ggcactacaa ctggcccagc
     2761 tacgattaag ccagtacctt tagcttttgg ccgtgctaag tagcgaatct gtttatcagt
     2821 cagattgaca atctctttta ggatagccaa atcttggggc ttttgtttga gcaaaatcat
     2881 aaactcacta tttgagagca atttccgacc ttcttcaaca gcagccagcg tttctacgtt
     2941 ctgggtaatt cctgttggaa tcgcaccata tttccgaatc cgtgaatata acgtagtaaa
     3001 gaagtctgct tgagccttat ttttaaatag aatctgcatc tcatcaaagt aaacccaagt
     3061 agtacatttt ccttgatttt ctacaatttg attccagata taatcctgaa tcaccatcaa
     3121 agcgaacggc ttcaatttgt gcgacaactt cttcaggtta aagataacaa agcgatgatt
     3181 aagatccacg ttggtattgt gagcaaaaat atcctgagaa ccagttgtat aggtctctac
     3241 tgctaaagct aagtcttgtg cttcaggttc gggttgttct tttaagacct ggtgccactc
     3301 ttttaatgtt ggggtaaaat tctccgtcaa atagcgttca taagtcaccc ctgttacccg
     3361 gtcaataatc ccaatctggg catctgtcac ctctgacaga atcgattcaa acaatcccat
     3421 taataagttt gccttatctc caatcggatc gtcatcctca tcgtccaaac gatctagatc
     3481 tggtagatct aagagattga tatgtgtttt agatccaatc gaaatatcca ccatctgagc
     3541 accgaaagca cggccaatat cagaatattc atcttcggga tccacgatga tcactcggtc
     3601 ttctggatat ttcagtaaag ttggaataac ttctccaccc tttattgttg tagatttacc
     3661 agatcctgaa gaacctaaca caactcctga acccgtgttc aaatcacgct ttctatctag
     3721 tgtaatgata ttgtttgata actgattttg accatagtag cgagcgagtg agctttcaga
     3781 cttcaagtcc acgttggtaa aaggaacttg cgtagcaata ttagctgtcg tcatctttct
     3841 cataaaattc ttcttcacat tcaagaagca ctctccaata ggtaaaaccg tatttagagc
     3901 ctcttcttgg taataataga gatcttcaaa ctctacccct agcttccgtc cagcacgctt
     3961 aatcttctgc tcattccgtt gtagttcctc ctggttatcc gccttaaaat acactgcaat
     4021 caaaccagaa aagattttct ggtcatactc agtaatctcg tctcgccact tcttggtagc
     4081 ttctgagatt tcttggtcac gaccagcaac gaccgcatca tcaaagatac cagattgagc
     4141 cgccttacgt ttcgaacgta acttcccaat ttcagcatct gtctctgcat cgtcaatctt
     4201 ctctaagatt tcaacgttct catagggttc tgcatggata gtaatagcca gttccagccc
     4261 cagtgtcgtc aaatctcgaa taagccgatc agacatccag ttaggatagc gacgtgcata
     4321 gagcaccttg caccaacgat catctataat catgcgtttt tcttgaaatt caatcctgtt
     4381 tggcgcaata aatgatttag tgaataaacc tgtcaaagca atttctttgt aatcaaaatt
     4441 gacatacggg ttatctcgta acagttcaga aaagaccttt aggcgatcca aaccattcat
     4501 atccctgaaa gtaatatcag attcctgaaa ttgagttcct aaggaaactc caatatcttg
     4561 taggatcaac tgcgcctgct ttcggtcatc cgcattcgtt gaaatggtca catacttatg
     4621 tacctcgaag ttgttagcat gtgtcgtaaa tcgctccttg atcatctcat ttagctcctc
     4681 acgatagtcg tcaaaaccat catttgtttc ttcatacaag atattctgca aggagttatc
     4741 cgatactcga cggttaatga ctaagagctg gtagttacta ccctcatcca gtgaattaag
     4801 agcatccatc gttgtatcaa tgatactctc tttttcatct tgttgagcag ttgagtacga
     4861 agcatccccc aacataaagc tccgagaata cttctcacgt gcaatgtgca tcaatccgtc
     4921 ttcatggagc agtgtataat tgatggtgtt ttgtgtcgta ggtttcatct ggcgacgcaa
     4981 gcgatcaatt tttttctttt ctgctttttc tagtttttct cttttgcttt tgaataaact
     5041 catctttcgt atacattcct acctttccaa attctatctc ataggttcgt tgttggattc
     5101 ggaaaaagaa attgattttt tctttaatcc gcattcgctt agtcattccc gtaccgtaca
     5161 tccctccagg aacgacaaat agagcatccc aaagatagat gtaccaatca ggtagaccaa
     5221 agaagtaact agcagttgtc cctgagacag ctattatcaa acacaggtat agaacaagca
     5281 ttctactagt taagccaaat agaataggct tgtcctcagt ttcaaattct cttaaaaatt
     5341 ctgatccaat ttttttcaat tagtttcctt cccatcaaaa aaaaacagtc cgtttagaac
     5401 tgttagtctt atgtcattta tttatcacgt tcctttacaa gcatagctac agcaatctca
     5461 gattcctacc ccttcagtat cgaataggct tctgttagcc gttttttgtt cctgaaaata
     5521 gcgttcaaag ttttcatctc ctttgaagac cattttacca cgatccatat atttaatcca
     5581 ctgttccaaa cggtaaacat actctgtttg actgatacta tcagctatag cacagtacgt
     5641 tatatcttcc tgaagaaggg taagaattct catgccataa aaagcatctt gcttagcttc
     5701 tgcatagcgc caagcataaa tatatagttc gtcaccataa ctactcatcc gaacggcacg
     5761 aggaatctca gatatcttaa ctttaccatc caatatccac tccaataaag gctccgataa
     5821 taattcatgt tcataggcaa accaagaaag acgtgttatt tcttgttcaa gagaagttat
     5881 tttatccttc aactctcttg tcccatgttt cttttgtaaa tcattaaatt gtttatttcc
     5941 tatctccttt aacgtttcca ttgatagtca cctctttcta tagaaaacat ccacacgatt
     6001 ctctaaacat aggtaacatc gattaattct aatttttcta cacatagatt acactcctaa
     6061 aagctgcttg gcttttcgac tagatccaac cattacaaag atatagataa cccccttggc
     6121 aattgaagca aaggctgttc cccaggaatc actggaacca gtcgtaacct ttaggatatc
     6181 tgctgcaaca atcgaatcat aaacaacaga aacaataatt aggatgacac caataagggc
     6241 agaggctgca aagtatttca ggaagttaat cgtaacagat cgcaacgaat ccatcataaa
     6301 gaaggctact aacaatggag ctaaagcctt aagcatatat aaatccaagt aacgtaagaa
     6361 aacaataatc cctaaaataa cgttagctac tccacttaca gctttcccta cgaaagtaat
     6421 gatagttttt tcaactattc ctttcccacc agaaatatta gaatcaatgg ttgctttaac
     6481 agtaggtgtt acatgagcaa ttacctttac aataatatta agtaattcca gaatggcatc
     6541 gcaaatttga gatgaggcag aaatcatgat gaaggcaaat aaatacttca tcaaggcctc
     6601 tagccaaatc ttttgggtta gcgaacctcc tctggactta accatttgtg accacgatgc
     6661 catttcaaac cagaaaaaaa gacctaaaag gatataccca ataggtctga ctgcatcagc
     6721 catcatattt acagcttgat ttgtagcaga gccataacta gaaagagagc ttgttagctc
     6781 tctaatatct aaattcatag gctactccta aaattttagc tgtgataatg ctgcaacgac
     6841 tgcggccgca atccctgcag aagcaacagc caagaacgca ccattaatca tagaatcaga
     6901 cccatcatct tgtctttgct tatctttatt ctttcttcct tgaatataat caaccgcacc
     6961 attccagatc cagataagac ctgtgattgt tccaactaca cctagaccag taataatttt
     7021 tgtaatgatt tccattttgt tttacctctt ttaatttcat ttttttataa caaaaggcac
     7081 tgcagagatt tctacagtgc caaacacaat actattttta taattcttca aattcttcac
     7141 gataaatcgt ccgaacagta gctactagaa tactgaggcc aataataatt ggaacttcaa
     7201 aattcggata tgggaaaaat aaccctcctc cttttggtgc atcaaccact tgaccagcag
     7261 taataagtga atcatgggac attcctaaaa tatgcggtgt ataccatcca aaaatattat
     7321 caattatgtt ttcgcttggg aaattgaata gatgatgaat gattgccatt cccccaatca
     7381 atacgattgt tatacatatt ttagctataa cccacagaat aaacatacca atagtggatt
     7441 ttacaacatt aatacaccaa agaacgatat aaaagggagc tgtaaaaatt ctaatgatag
     7501 ctacccataa ccaggaaaaa tcacttccaa atttcataat cctactcctc cacgatttac
     7561 cgttattata ccataaaaat agcttatttt aaagattcct agagtattct aagcctcttt
     7621 tttcttgcgc ttgctgtaga gcaatcctga agcagcaccc cccattgcca gaccagctaa
     7681 cagcaattct gcagaagcct gctcacctgt agatggcagg cttcgttctg gttgttgcgg
     7741 atgttcttca ggagttttgg gctcttctgg agtctgagtc acaaccgtat tggaagcaac
     7801 ttccacaccg ttaactgtat gatagtaagt attttctact gctcctgact gaatgcgtgt
     7861 catttgtaga tatacttctg cttgaaactc tgatgtttct aaaatcgact ttaagagagc
     7921 atcatcaaag ctaatatcta ctttaccttt agccttgtct accacttgac ttgtgaactt
     7981 agttaattca tcaccagctt tgaatttttg gccatcactt gtttcaaaat ctacagcagc
     8041 aaataccttg taaacactct gataatcatc atgtgtttca tcgtagtcat cgctaaattt
     8101 atactcaaat aactgttctg agcgatcttt tggcactagg gaaccaacta atttgtaatt
     8161 aaatgtttga ttcagtttga cctcttttcc atccaagctt tctttgctta gatggtcgat
     8221 cacaacatct ttcttcggtt cgatctttgg tacattattg actactgttt cagttacata
     8281 atccatccca aaatcaattt gataggctgt attttcatac ttaccacctg tttgacccaa
     8341 ttccttctta acagtcattg gattggtaat ggtcagaact tctccagctt gcacgtaggt
     8401 cttgtagaat tcctctggat tctctgcctc gaatacttga atcgctcctt tcggagtgaa
     8461 atggctagac ttcagggctt cttggacacc tgatggtgcc ttagctagac tctcataaag
     8521 agacattttc aaatctttga ctacttgacc tttagaatcc gttacttgaa caccgtcttg
     8581 attgatggta acagcttctt ctggataatc atcaacgata tagaaccctt taccaatacg
     8641 gtctttatct gcttcaatgc ccttgtattg gctataatct gccgttacct tgtagtagtt
     8701 gacagagtct gccaatacct gtttcccatc gatgttcacg cctgctttat tcaaattctt
     8761 cttggtaggt ttaacagtag gaacattatt gacaactgta tctgtaatat aagctgaacc
     8821 aaaatcaagc tgataagctg tattctcata cttaccacct gtttgaccca attccttctt
     8881 gacagtcatt ggattggtaa tggtcagaac ttctccagct tgcacgtagg tcttgtagaa
     8941 ctcctctgga ttctctgcct cgaatacttg aatcgctcct ttcggagtga aatggctaga
     9001 cttcagggct tcttggacac ctgatggtgc cttatccaga ctatcataaa gagccatttt
     9061 caaaccttta actacttgac ctttagaatc cgttacttga acaccatctt gattgatggt
     9121 aacagcttct tctggataat catcaacgat atagaaccct ttgccaatac ggtctttatc
     9181 tgcttcaatg cccttgtatt ggctataatc tgccgttacc ttgtagtagt tgacagagcc
     9241 tgctaagacc tgtttcccat cgatgttcac acctgcttta ttcagatttt tcttggtagg
     9301 tttcgcagta ggaacattgt tctctacctt atccgtctgg tagccactac caaagtctaa
     9361 ttgataagct gtattctcat acttaccacc tgtttgaccc aattccttct taacagtcat
     9421 tgggttggta atggtcagaa cttctccagc ttgcacataa gtcttgtaga actcctctgg
     9481 attctctgcc tcgaatactt gaatcgctcc tttcggagtg aaatggctag actccaagga
     9541 ttcttgtaca cctgatggtg ccttatccag actatcataa agagccattt tcaaaccttt
     9601 gaccacttgc cctttagaat ccgtcacttg aacaccgtct tgattgatgg taacagcttc
     9661 ttctggataa tcatcaacga tatagaaccc tttgccaata cggtctttat ccgcttcaat
     9721 gcccttgtat tgactataat ctgccgttac cttgtagtag ttgacagagc ctgccaagac
     9781 ctgtttccca tcgatgttca cacctgcttt gttcaaattc tttttggttg gtttaacagt
     9841 aggaacatta ttgacaactg tatcagtttg atatccgtta ccaaaatcaa cttggtaagc
     9901 cgtattctca aatgattttc ctgtatttcg cagttcttcc ttagttacca ttggatcaat
     9961 aattgtaacc gattttcctg atttaatata ctggttaaaa taagcttctg gatcatccac
    10021 taaaaatact tggaaagcac ccttgggctt aatttcagaa ctagcaagaa aagctttaac
    10081 cttatcatta tcaacggcat ctatagaatc atactgatac accgagatac cagcaacttc
    10141 ttttccttcg ctgtcaatat aacgaatgtc cgattgatta atcgtaacag cctcttctgg
    10201 gtaatcatca attgctccga atccttttaa aatagtagat gaatctgcct tcatcccctt
    10261 atattgatca taatccaagg taatatggta gtaatttgtc gaaccaacta gaactggttt
    10321 accatcaatg ataactttat ccttattgta attatgttta agaggttgaa tgaaattatt
    10381 attcggattg tccggatcat tcggtttacc aggtgttgaa atctgaacaa tgtttgaata
    10441 acttgcgtac ttattgttaa tctttaattg gaagttattc ttgtaggtcg ctccatcatt
    10501 cgttacttta ccaactaaaa ttggagctgg tacttgtact tccttactta aatcttgatt
    10561 aagcttagat tttaaacttt ctaagccttt catccgaaca acatggctcg actcgtcata
    10621 agttaattca aaatctgagc taattttttt ggaagcttca acatctaaca caaaacctga
    10681 aggcaaggca tccacaattt caaagtctgt aatagcttca cgattagctg gaagaggctt
    10741 agttgttagt tcccactgta ctgttgaaag tttaggtaca tagcttttat caatagattc
    10801 accagaagaa ttttttacaa acttttctag gtcaggcatt gcctgtaagc gtgcatatct
    10861 aacccttact gttggagggg atactaaaga ggggatctct ttttccttta tctcctcagg
    10921 tttgggtggg agtacctctt caggttttcc agttggagaa ttgggtggag tagtttcaac
    10981 ttcataagtt ggtttgcgag gtggatttac tggtggaatg cttttcaact ccgccccctc
    11041 cccaagaatt gtgaagacaa cgttttgaac atttccactc aaattctctg catcccattc
    11101 agcgggagtt cttccctctg tcgaaccagg agatgatgtg tgaaggtacg ttaaactaga
    11161 accataccct actgaagcaa aggaagcctt aggaatatct gaggtatcat taactccatt
    11221 ttctactccc ttcataacgc gaccatcaaa atccaaacct gaaccacttg gattaagaac
    11281 cattccacga ccagatgagc cataactcaa atttgaacct tgaccccaat ctacatcggt
    11341 aataactgtt ccaattaaga gggaaacagg agttgtcgta ccttcaatat aaaaatcaaa
    11401 aaccatttcc aaacgggtat gattattata gacaaagtag aaacttccac catctccacc
    11461 cttgaggtag atatctgaat ctgtcacagg aacaccattt cgaacttctc cctgatagtc
    11521 tcctaaatcc gaaaccatga cttttgccat gatctttcta ccatctgtca acgttccaat
    11581 attatgaata taaaatgtat ctccaaatgt tggagattta atgatatcat aagtttccgt
    11641 actatcctta ctaactcgag ttcctgcgcc tcctgttaca taagtatctg catgataacc
    11701 taaaaaacca cgcatactct ctactggtag attatcatct ggtactactg taaaatcatt
    11761 ataatagtct aagcttcccc gaccagctga attatatcct ccataaactt tgaaacctgt
    11821 ttcagatcca aataaaggct tacttgtttg aattgcatct cgctcagctt taatagttgc
    11881 tagcttcttt gtatagtctg tcaaagagct ttcataagct cctctcttag cttcatttcg
    11941 ttttcggatt tctgcattct cttgattgat acgatctatt tctgcctgat tctctcgttg
    12001 atttttttca ttctctgcac gaatactagc attcttctga ttaattcgat tcacttcagc
    12061 ttgataagaa gttaaatcct tttgatattg ttccttcttc gcagtatttt catcttggat
    12121 tttctttcgg ttcgtttgat tttgtctttg atcttcacga tatttttcag tagctttctc
    12181 aatactatct gcttgtgtgc aataatcact ctcgacttcc ttttgctttt ttccaactca
    12241 gaggctgtac ttgcagttcc tttatctact acagaatcaa attccacctt caatccagct
    12301 tcttgtgcct ttcgaatagt ttcatctaaa ctggaatgag aaatagaaac ttctaacgtt
    12361 cctgtttttt cttcactctt tccttgattt tcagtagaaa tactgcttgg actcgtctgg
    12421 gcataaggcg catttgtagc cttattttca gttcgttcat ctgctataac tgggcttatc
    12481 atgcttaaag ctgctaaacc tagtatcact ccacaagttc cataaatttt tgatttccga
    12541 atagatccat atgtttttgt ttctcttgct ttgtgcattc tatctcctta tctaaaatat
    12601 caatcaatat aaaacctcaa atgttggctc tcgaggtctc ttataatata aaatcatctc
    12661 tttcctttcc aatagaaaaa agccagcttt cactgacttt tctatacaat attgtaatga
    12721 attttaagaa atccacttac cagaataatc taaataataa gcaccaatcg tctcattttg
    12781 tgccatctta ccatctgctt tcaaataata ccaagcactt ccgtccttga accattgatc
    12841 tctcagataa cttccatctg atttgagata gtaccaagct ttataactgg aatc
//
LOCUS       DAVDZK010000052        12205 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVDZK010000052 DAVDZK010000000
VERSION     DAVDZK010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12205
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.053"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            223..531
                     /locus_tag="VUX16_001910"
     CDS             223..531
                     /locus_tag="VUX16_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET8124813.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKLYTTTSF
                     "
     gene            579..1781
                     /locus_tag="VUX16_001911"
     CDS             579..1781
                     /locus_tag="VUX16_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET8124814.1"
                     /translation="MHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLDEPS
                     NDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHL
                     DYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGRLLA
                     KKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLSIDD
                     RVLAQELRLTVRGQEKIGIIGPNGVGKSTLLAKLKQFLNDKREISLGFMPQDYHKKLQ
                     LDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDLVLR
                     KPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSSIYRLTEHGL
                     ELVNLEDV"
     gene            complement(1825..2724)
                     /gene="htpX"
                     /locus_tag="VUX16_001912"
     CDS             complement(1825..2724)
                     /gene="htpX"
                     /locus_tag="VUX16_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET8124815.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(2726..3286)
                     /locus_tag="VUX16_001913"
     CDS             complement(2726..3286)
                     /locus_tag="VUX16_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET8124816.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPNNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            3380..4093
                     /gene="rsmG"
                     /locus_tag="VUX16_001914"
     CDS             3380..4093
                     /gene="rsmG"
                     /locus_tag="VUX16_001914"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET8124817.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFECYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            4445..5728
                     /locus_tag="VUX16_001915"
     CDS             4445..5728
                     /locus_tag="VUX16_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET8124818.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(5923..7494)
                     /gene="ffh"
                     /locus_tag="VUX16_001916"
     CDS             complement(5923..7494)
                     /gene="ffh"
                     /locus_tag="VUX16_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET8124819.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHQVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPI
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSAPGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(7506..7838)
                     /locus_tag="VUX16_001917"
     CDS             complement(7506..7838)
                     /locus_tag="VUX16_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET8124820.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            complement(7929..8306)
                     /locus_tag="VUX16_001918"
     CDS             complement(7929..8306)
                     /locus_tag="VUX16_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET8124821.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGNYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            8378..9682
                     /locus_tag="VUX16_001919"
     CDS             8378..9682
                     /locus_tag="VUX16_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET8124822.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSLIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            9695..10501
                     /gene="yidA"
                     /locus_tag="VUX16_001920"
     CDS             9695..10501
                     /gene="yidA"
                     /locus_tag="VUX16_001920"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET8124823.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLADLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(10712..12019)
                     /locus_tag="VUX16_001921"
     CDS             complement(10712..12019)
                     /locus_tag="VUX16_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124824.1"
                     /translation="MLVDFINNSQRQYSFINADGISVEDITDEKNLKFYFYGPVKGEI
                     FRYQEKHDLFLYYRDPLTSVEVPVENTIKVVEMYEETDLIIKVGDYIFQDVKRHRFPD
                     GSVELHFGDCFKMSFDVNKKIFKFNYTRSNMLSKAIECTEVLQELGRVGYFNLNGNKI
                     ELDKQSISDITSQNLDSDIKDLKQISNILKNIGVQKDLDLNCFDKQSQKNLNILNSGL
                     VLKEKVALDYNESKLLHLRIANIHIITLYDYAIDKNGFMINIFTETPWCRRGEDEGGL
                     DISIFEPNYWLKIDNCDFDSVIASYQRLVDNQLRYEGTNNTIIKIVVAADKAEDVSRS
                     ELLLNWAQCLSDWNLKYSKNCEMAIINDLQIKSRVRKLNSKETETLTNILVNSNDNYE
                     LCFGSSVLLKSKPQADLFWNKLDNETKERYKDFPIYTLYMKLS"
BASE COUNT         3671 a         2655 c         2179 g         3700 t
ORIGIN      
        1 ttttctgttg acaaaatttc cttaaaggta taatataaag atactaatac tcggaggtaa
       61 gggagacatg aacaactaag tctatcaaat aaagaacctt tatttagtag atcttgtttt
      121 tgtctctttt tgtgtgctct tttatgctct ttttctggca tgttaataga gtttttttga
      181 catagacttt gggatctact aggtaaagta gagctttttg ttatgcacta tgaacattct
      241 agaaagggaa atcatatgat aaaaatcaat cacctgacca tcacacaaaa caaagattta
      301 cgagaccttg tctctgacct aagcatgacc atacaagacg gggaaaaggt agctattatt
      361 ggcgaagaag gaaatggtaa atcaacctta cttaaaactt taatggggga agatttgtct
      421 gatttcacta tcaagggaga catccagtct gattatcagt cactggccta cattcctcaa
      481 aaagtccctg aggacctaaa aaaaaaactt tacacgacta cttcttttta gattctattg
      541 atttagacta cagtatcctc tatcgtttgg cggaggaatt gcattttgat agcaatcgtt
      601 tcgcaagtga ccaagagatt ggcaatctat cagggggcga agctttgaaa attcagctta
      661 tccatgagtt agccaaaccc tttgagattc tatttttaga tgaaccttca aatgacctag
      721 accttgagac agttgattgg ctaaaaggcc agattcaaaa gaccaggcaa accgttattt
      781 tcatttccca tgatgaagac tttctttctg aaacggcaga cactattgtc cacttgcgac
      841 tggtcaaaca ccgtaaagaa gcggaaacgc tagtagagca tttagactat gatagctata
      901 gtgagcagag aaaggctaat tttgccaaac aaagtcagca agctgctaac aaccaaagag
      961 cctacgataa aaccatggaa aaacatcgga gagttaagca aaatgtagaa actgcgcttc
     1021 gagctaccaa agatagtact gccggtcgcc tattggctaa aaagatgaaa actgtcctct
     1081 cacaagaaaa acgctacgaa aaggcagctc agtccatgac tcaaaagcca cttgaagagg
     1141 aacaaatcca acttttcttt tcagacatcc aaccattacc agcttctaaa gtcttagtcc
     1201 aactggaaaa agaaaatttg tccattgacg accgtgtttt ggctcaggaa ctgcgactaa
     1261 ctgtccgtgg gcaagaaaaa atcggtatta tcggaccaaa tggtgttggg aaatcaactc
     1321 tgttagccaa attaaagcaa tttctgaatg ataaaagaga gatttccctt ggttttatgc
     1381 cacaagatta ccacaaaaaa ctgcaattgg atttatcctc aatagcttat atcagcaaaa
     1441 ctggggaaaa agaggaactt cagaaaatcc aatctcacct agccagtctc aatttcagtt
     1501 atccagaaat gcagcatcaa attcgctcct tatctggcgg acaacaggga aaactcctgc
     1561 ttttggattt agtcctgcgc aaaccaaact ttctcctgct ggatgaaccc acacgaaact
     1621 tttctcccac ttctcaaccc caaatcagaa aactctttgc aacctatcca ggcggtctca
     1681 tcactgtttc gcatgaccgt cgtttcttaa aagaggtctg ttcaagcatc taccgcttga
     1741 cagaacacgg tttggagtta gttaatttag aagatgtata aatttgcaac atagcaaaaa
     1801 tccagagacg acctctggat tcttttacat ctgttttaaa cgttcaatcc gttctgagat
     1861 aggtgggtgg gtataaaaga gtttttggaa ccccccacct ttcttgggat cattgatata
     1921 aagggcactg ctagcatcat cgacgtggcg actcataggt ttgctattgt ccaacttatc
     1981 tagggcatta atcattccct ggggattgcg agtcagctcg acactagatg catctgccag
     2041 aaattccctc tgacgagaaa tagcgagctg aaccaaggtt gcagcgagag gtgccagtac
     2101 aatagctagt agggaaacca ctagcataat gatttcaaga ccatttccat ctcggtcatc
     2161 atcacttcgt ctgcgacctg ctccacccca ccacatcata cgacctgcca tactagaaag
     2221 catggtgata gcactagcaa gggcaactgc aatagtcgaa atacggatat cataattacg
     2281 aatatgacta acttcatgtc ccataacagc ttctagttct tcacgattca tgatagctag
     2341 tagacctgaa gtcgcagcaa cagccgcatt ttgaggatta gaacctgtcg caaaggcatt
     2401 taaggctgga tcatcaatga tgaaaacacg gggcatagga atctgagcga ccagagccat
     2461 atcttccact acatggtaga ggtctggtgc cgtttgctca tccacctcac gcgctccatt
     2521 catggacatg acaatctctg tcgattgaaa aatcatagac aaagcgtaga taaagccgat
     2581 aatcagtgcg ataaccaaac caccaagtcc agatcttata aagagataac caaccgcata
     2641 accaacaaga gctaagagta ggaaaaatac cagcaacaaa atccaggttt ttcgtttatt
     2701 gcttgcaatt tgatcaaaca acatcttagt cacctaaacc gctaaaatca actttaggaa
     2761 ccgacttttc ctcttcaggt gtttgaagga aatctgccgc tttaaatcca aacattccag
     2821 cgataatatt gttcgggaaa gtttctaatt ttacattgta gttgctgaca acactgttat
     2881 agagttgacg agagtaagaa attttatttt ctgtgtttgt caactcctct tgcaatttaa
     2941 caaagttagc actagctttc aaatctggat agctttctgc aactgcaaaa atacctgaaa
     3001 cctgacgagt gagggcatca ctggctttca tagcttctgc tggtgaagtc gctgccgcca
     3061 cttggttacg tagttctgcc accttttcaa gggtagaacc ttcatatttg gcataacctt
     3121 ttacagtctc aatcaagttt ggcaagaggt catttcgacg tttcaactga acatcaatct
     3181 gactccaagc ctccttggtt tgcatacgat ttttaaccaa accgttatag ctaacaatca
     3241 caaaaataac aataagagcg ataactccaa gaataatcca agtcatgata taagtccttt
     3301 ctacttttag attagtacca gtatatcaaa tttttaatga ttgtggtaaa ataagatgat
     3361 actaaagaag gaaataacta tgaaaccaaa aacattttac aacttgcttg ccgagcagaa
     3421 tcttccactt tcggaccagc aaaaagaaca atttgaatgt tattttgagc tcttggtcga
     3481 gtggaatgag aagattaatt tgacggcgat tacggacaag gaagaagttt atctcaaaca
     3541 tttttacgat tcgattgcac ccattcttca aggtttgatt cccaatgaaa ctatcaaact
     3601 tcttgatatc ggggctgggg caggatttcc tagtctacca atgaaaattc tctatccgga
     3661 gttagatgtg accattattg attcactcaa taagcgcatc aacttcctac aactcttggc
     3721 tcaagaactg gatttgaacg gagttcattt ctaccacgga cgtgccgaag attttgccca
     3781 agacaagaac ttccgtgctc aatatgattt tgtaacagct cgtgcggttg cccgtatgca
     3841 ggtcctatct gaattgacta ttccctacct taaggttggt ggaaaactat tggcactcaa
     3901 ggccagcaat gcgcctgagg agttgttaga agctaagaat gccctcaatc ttctttttag
     3961 taaagtcgaa gacaatctca gctacgccct accaaataga gatccgcgtt acatcacagt
     4021 ggtagaaaag aaaaaagaaa caccaaataa atatccacgt aaggctggta tgccaaataa
     4081 acgcccgctt taaattttta agtaaaaaaa tatttacaaa atcaacctcg ctctcttatt
     4141 tttaggctcg ggaaaaaatg atttacaaaa tcagcctcgc tcttttattt ctaggctcgg
     4201 gaaaaaatga tttacaaaat cagcctcgct cttttatttc taggctcggg aaaaaatgat
     4261 ttacaaaatc atttttttct gctatactat cctaagcaaa ggtttttaat gtcatcccgt
     4321 gaggtgacga agacgcagaa atatttaaaa ctctttaaaa tctaaatttt aaagaagtct
     4381 tactctgagg gcctattgct gtaaaataat gggctctttt ttgatgccca aaagtgaggt
     4441 ttatatgaaa caagaatcaa ctgttgattt gttactagac gttgaccaac gtccttcggc
     4501 tggaaaagga attctcctta gtttccaaca cgttttcgcc atgtttggtg cgaccatctt
     4561 ggtaccattg attttgggaa tgcctgtatc tgttgccctt tttgcttcag gtgttggaac
     4621 actcatttac atgattgcta ctggttttaa agttccagtt tatctaggtt cttcattcgc
     4681 ctttatcaca gctatgtcac tggctatgaa agaaatgggg ggggatgtat ctgctgctca
     4741 aacaggggtt atcttgactg gtttggtcta tgtccttgtt gctaccagca tccgatttgt
     4801 aggaacaaaa tggattgata aactcttgcc accaatcatt atcggtccta tgatcatcgt
     4861 tatcggtctt ggacttgcag gttcagctgt taccaatgca ggtcttgtag cagacggaaa
     4921 ttggaaaaat gctctggtag ccgttgttac tttcctaatt gctgccttta tcaatacaaa
     4981 aggaaaaggc ttcctacgaa tcattccatt cctctttgcc attatcggtg gttacctctt
     5041 cgcactaact cttggtttgg ttgactttac gcctgtccta gaagctaact ggtttgaaat
     5101 tcctggtttc tacttgccat ttagcacagg tggtgccttt aaagagtaca atctttactt
     5161 tggtccagaa gccatcgcta tcttgccaat cgctatcgta acaatttctg aacatatcgg
     5221 agaccatact gttttgggtc aaatctgtgg ccgtcaattc ttaaaagaac caggtcttca
     5281 ccgtactctt attggtgacg gtatcgcaac ttctgtttct gccttccttg gtggaccagc
     5341 caatacaact tacggagaaa atacaggggt tatcggtatg actcgtatcg cttctgtctc
     5401 agttatccgt aacgctgcct tcatcgcgat tgccctcagc ttccttggta aattcactgc
     5461 cttgatttca actattccaa acgctgtact tggtggtatg tcaatccttc tctatggggt
     5521 tatcgccagc aatggtttga aagtcttgat taaagaacgt gttgatttcg ctcaaatgcg
     5581 aaacctcatc atcgcaagtg ctatgttggt tcttggactt ggaggagcta tccttaaact
     5641 tggtccagtt acactttcag gtactgccct ttcagccatg acaggaatca tcttgaactt
     5701 gatcttgcca tacgaaaata aagactaaga gtctaaatac acctaatcca ctcagctgtc
     5761 tgagtggatt tttcgtatac cataataaaa gtgtcttaac aaaattatta aaatcaaaaa
     5821 acgtataata tcagatattc taaaaccttg atactgtacg ttttatcata gaaattttta
     5881 ctttattttc tcatcaaatg agatttgcat caatctcttg tcttacttgc gtttcttctt
     5941 cgctttcttc attttgttag ccatacgttt catggactgt ttcatggcaa attcaccaat
     6001 tttacctttc aaaccgccac caaacatctg gctcatatct ggcattcctg ctcctccggg
     6061 agctgataag tcaggcatac cgccttgtcc catcattcct tcaagggcag acatatccat
     6121 tcctcccata tttggcatat ttttaggaag gttatttgga ttaatcccca tttgcttcat
     6181 cattttattc atatccccag acataacacc ctgcatgagc tgtttagcct ggttaaagtc
     6241 cttgatgaat ttattgactt cgacgaatgt atttccagaa ccagcagcaa tacgacggcg
     6301 acggcttgga tttaacaaat ctgggttttc acgttcttca ggtgtcatcg aagacacaat
     6361 ggcacgttta cgagcaatct ggcgttcatc caccttcatg ttttgaagtg ctggattatt
     6421 ggccatacct ggaatcatct tgagcaagtc ttccattggc cccatgtttt gtacctgatc
     6481 caactgatca atgaaatcat tgaaatcaaa ggtattttcg cgcatcttct cagccatttc
     6541 aagggctttt tgttcatcgt attcctgaga agctttctca atcaaagtga gcatatcccc
     6601 catgccaagg atacggctag acatacggtc tgggtggaag gtttcgatat ctgtaatttt
     6661 ttcacctgta ccagtgaact tgattggttt tccagtgatg tgacgaacag acagagcagc
     6721 accaccacga gtatcgccat caatcttggt aaggatgacc ccagtcactt ccaactgagc
     6781 attaaactca cgcgcaacat tggctgcttc ctgaccaatc atagcatcaa cgacaagcaa
     6841 gatttcattt ggttgagcca atgctttcac atcacgaagc tcattcatga ggagctcatc
     6901 aatctgcaaa cgacccgcag tatcaatcaa gacatagtcg ttatgattag tttgggcttg
     6961 ctccaaacct tgacgtacaa tctcaacagc tggtacttct gttccaagtg caaagacagg
     7021 cacatcaatc tgttgtccca aggtcttaag ctggtcaatg gcagctggac gataaatatc
     7081 cgccgcaatc atcaaaggac gagcattttc ttctttcttg agtttgttgg ccaatttacc
     7141 agcaaaggtt gttttaccag ccccttgtaa accaaccatc atgatgatga ttggaatctt
     7201 aggtgacttg ataatttctg ccgtatcaga acctaaaacg gctgtcagtt cctcatcaac
     7261 gattttaata atctgttgcg caggattaag tgtatcaatg acctgatgcc cgactgcacg
     7321 ctcacgaact ttcttgataa agtcctttac aacaggcaag gcaacgtcgg cctcgagcaa
     7381 ggccaagcga atttctttgg ttgcctcttg gacatcagat tcagagattt ttcctttttt
     7441 acgtagattt ttaaagacgt tctgcaaacg ttctgttaaa ctttcaaatg ccatttttct
     7501 tcctcttatt ctctattatc aatgcttgtt aaaatttcta tctgctcctg cagaaagtta
     7561 tccttgggat agcgctccaa aatctgatca aaaatctgac tgcggacaat atagtccgag
     7621 tacatgtgca atttcatctc ataatcttcc agaatctttt ctgttcgctt gatattgtca
     7681 tagacagcct gacgactgac accgaactcc tcggcaattt cagcaaggct gtaatcatca
     7741 gcgtagtaga gctcgatata attcatttgc ttatctgtca aaagcgccgc ataaaattca
     7801 aagagcgcat tcatacgatt ggttttttcg atttccataa cttttattat accaaaaatt
     7861 agcctaatct accacactag gaagccgatc caagaagata gatagctaaa tttgaaaaag
     7921 acatgagcct agccccaagt aatttccaat tgatagctgg caaagggatg tccctcttga
     7981 ttttgtagtt gataatctag ttcaatcttt tgcctatcaa cttgataatg gctcgtttgg
     8041 atgataaact cctgcatgcc cataggtgta ggaatatagg ctaaactatc gctatccttt
     8101 agaaagcgca taatggtctt gggattagaa aatcggctca tcacaagttc ttgaccatga
     8161 aatttaatca ctactttttc cttttcctca ttataaaaga gtaaatagct ataatttccc
     8221 ttttcatgca cttccacatc ataaagctgg tcaatcactt ccaactgctc atcaaactga
     8281 atcgtatttc gcatccgaat cttcacatca agtcctcttt cttgtctctt gtcctactat
     8341 tttaccaaaa agagcaggat tttgctataa tggtcatatg aacgaaaaag tattccgtga
     8401 cccagttcac aactacatcc atgtcaataa tcaaatcatc tatgacttga ttaatacaaa
     8461 agaatttcag cgtttgcgcc ggatcaaaca actgggaact tccagttata ccttccacgg
     8521 tggagaacac agtcgcttct ctcactgtct aggagtctat gaaattgcac gacgcatcac
     8581 agagattttc gaagaaaaat atcctgagga atggaatcct gccgagtctc tcttgaccat
     8641 gaccgctgct ctcctacacg accttgggca tggtgcctac tcccatactt ttgaaaatct
     8701 ctttgataca gaccatgaag ccattactca ggagattatt caaaatcctg agacagagat
     8761 tcaccaagtc ctgctacaag tggcacctga tttcccagaa aaggtggcca gtgtcattga
     8821 ccatacctat cctaataagc aggtcgtgca gctcatttct agtcagattg acgcagatcg
     8881 catggactat ctcttgcgcg actcctattt tacaggagca tcctatgggg aatttgacct
     8941 gactcgcatc ctccgagtca ttcgtcctgt cgaaaatggt atcgcctttc agcgcaatgg
     9001 catgcacgcc atcgaagact acgtcctcag tcgctaccag atgtacatgc aggtttattt
     9061 ccacccagca acacgcgcca tggaagttct cctacagaat cttctcaagc gcgccaagga
     9121 actctaccct gaggacaaga atttctttgc acgaacttcc ccacatctcc tgcctttctt
     9181 cgaaaaaaat gtgaccttga ctgactatct ggctctggat gatggcgtga tgaataccta
     9241 cttccagctt tggatgacta gtcctgacaa aattcttgca gatttatctc aacgctttgt
     9301 caaccgcaag gtctttaaat ccattacctt ttcacaagag gaccaagatc aacttactag
     9361 catgagaaaa ttggttgagg acatcggctt tgatcccgac tactatactg ccattcataa
     9421 gaactttgac ctcccttatg atatctatcg tcccgaatct gaaaacccac ggacacagat
     9481 tgagatttta caaaaaaatg gagaactggc cgaactctct agcctgtctc ttatcgtcca
     9541 atcccttgct ggcagtcgcc acggagataa tcgtttctat ttccctaaag aaatgttaga
     9601 ccaaaacagc atcttcgcaa gcattaccca gcaattttta cacttgattg agaacgatca
     9661 ttttacccca aataaaaact agaagaggaa atttatgagt attaaactaa ttgccgtcga
     9721 tattgacgga accctagtca acagccaaaa ggaaatcact cctgaagtct tttctgccat
     9781 ccaagatgcc aaagaagctg gtgtcaaagt cgtgattgca actggccgcc ccatcgcagg
     9841 tgttgccaaa cttctggccg acttgcagtt gagagaccaa ggtgactatg tggtgacctt
     9901 caatggtgcc cttgtccaag aaactgctac tggccatgag attatcagcg aatccttgac
     9961 ctatgaggat tatctggata tggaattcct cagtcgcaag ctcggtgtcc acatgcatgc
    10021 cattaccaag gacggtatct atactgcaaa tcgcaatatc ggaaaataca ctgtacacga
    10081 atcaaccctc gtcagcatgc ctatcttcta ccgtacccct gaagaaatgg ctggcaaaga
    10141 aattgttaaa tgtatgttta tcgatgaacc agaaattctc gatgctgcga ttgaaaaaat
    10201 tccagcagaa ttttacgagc gctactccat caacaaatct gctcctttct acctcgaact
    10261 ccttaaaaag aatgtagaca agggttcagc cattactcac ttggctgaaa aactcggatt
    10321 gaccaaagat gaaaccatgg caatcggtga tgaagaaaat gaccgtgcca tgctggaagt
    10381 cgttggaaac cccgttgtca tggaaaatgg aaatccagaa atcaaaaaaa tcgccaaata
    10441 catcaccaaa acaaatgacg aatccggcgt tgcccatgcc atccgaacat gggtactgta
    10501 aaaggaaaga atagataaaa accgctcagc tgagcggttt ttgtatgaat atatcacaat
    10561 gagagtaaat taataaattt aattgcagtt gtacagttac ttaaatcttg agagtacaaa
    10621 aaataggcat tgctttctta atttgtggta ctgaattgta ataaatcact ctctatttct
    10681 atatgttatc tctttataat ctcttttaat tttacgataa tttcatatac aaagtataaa
    10741 taggaaagtc cttatatctt tcttttgtct cattatccag tttattccaa aacaaatcag
    10801 cttgtggttt cgattttaat agcactgatg aaccgaaaca aagttcatag ttatcattac
    10861 tatttactaa aatattagtt agtgtctctg tttctttgct gtttaattta cgaactctag
    10921 attttatttg aaggtcattt attatagcca tctcacaatt ttttgagtat tttaagttcc
    10981 agtcagaaag acattgtgcc caattaagca ataactcact tctagaaaca tcttctgcct
    11041 tatcagcagc cacaactatt tttataatag tgttattagt accttcatat ctcaattgat
    11101 tatcaactaa tctttggtaa gaggcaataa ccgaatcaaa atcacaatta tctattttta
    11161 gccaatagtt aggttcaaaa attgaaatat ctaaaccacc ttcatcttca cctctcctac
    11221 accaaggagt ttcagtaaag atattaatca taaaaccgtt cttatctatt gcataatcat
    11281 ataaggtaat aatatggata ttagcaattc ttaaatgaag taatttggac tcattataat
    11341 ctaaggcaac cttctccttt agaacaagcc ctgaatttag gatatttaga tttttttgag
    11401 attgtttatc aaagcagttt agatctagat ccttttgtac acctatattt tttaatatgt
    11461 tagaaatctg tttcaaatcc tttatatcac tatctaaatt ctgtgaagtg atatccgata
    11521 ttgactgctt atctagttct attttatttc cgttgagatt gaaatatcct actcttccta
    11581 gctcttggag cacctccgta cactctatag cttttgatag catattggac cttgtatagt
    11641 taaatttaaa tattttttta tttacatcaa aggacatttt aaaacaatca ccaaaatgga
    11701 gttctacact cccatcagga aaacgatgcc tttttacatc ttgaaaaata taatcaccaa
    11761 ctttaatgat aagatcagtc tcttcgtaca tttcgacaac ttttatggta ttttcaactg
    11821 gtacttcaac actagtaaga ggatctctgt aatatagaaa aagatcatgc ttttcctgat
    11881 aacgaaagat ctctcctttc actggaccat aaaagtaaaa ctttagattt ttttcatcag
    11941 taatgtcctc aacggaaatt ccatctgcat ttatgaaact atactgcctc tgactattgt
    12001 taataaaatc cactaacatt ggatacattt ctttctcatc caatttaaat atccgaacag
    12061 aaagtttctt actatttgta gttttattat ttaatctact ttttttagca atttttttat
    12121 agataaagga ggcaatgact tatagtatat ttctcttaaa tcattatttt cacttagcca
    12181 gacaacgaat aaaaccacac cacca
//
LOCUS       DAVDZK010000053        11894 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVDZK010000053 DAVDZK010000000
VERSION     DAVDZK010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11894
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.054"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(50..1252)
                     /gene="rpsA"
                     /locus_tag="VUX16_001922"
     CDS             complement(50..1252)
                     /gene="rpsA"
                     /locus_tag="VUX16_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET8124825.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1414..1485)
                     /locus_tag="VUX16_001923"
     tRNA            complement(1414..1485)
                     /locus_tag="VUX16_001923"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1451..1453),aa:Gln,seq:ttg)
     gene            complement(1495..1575)
                     /locus_tag="VUX16_001924"
     tRNA            complement(1495..1575)
                     /locus_tag="VUX16_001924"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1539..1541),aa:Tyr,seq:gta)
     gene            complement(1625..1855)
                     /locus_tag="VUX16_001925"
     CDS             complement(1625..1855)
                     /locus_tag="VUX16_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET8124826.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2023..2667)
                     /gene="pcp"
                     /locus_tag="VUX16_001926"
     CDS             complement(2023..2667)
                     /gene="pcp"
                     /locus_tag="VUX16_001926"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET8124827.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDVVLCIGQAGGRIGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYLSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2682..3605)
                     /locus_tag="VUX16_001927"
     CDS             complement(2682..3605)
                     /locus_tag="VUX16_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET8124828.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3602..4291)
                     /locus_tag="VUX16_001928"
     CDS             complement(3602..4291)
                     /locus_tag="VUX16_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET8124829.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4434..5033)
                     /locus_tag="VUX16_001929"
     CDS             complement(4434..5033)
                     /locus_tag="VUX16_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET8124830.1"
                     /translation="MACGKTDKEADAPTTFSYVYAVDPASLDYSIATRTSTTDVIGNV
                     IDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQEPASYLNIMDPKSGSAMKHLGITKGK
                     DKDVVAKSGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMPTASFGGSPV
                     VSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDIVTTKEYN"
     gene            complement(5116..6138)
                     /locus_tag="VUX16_001930"
     CDS             complement(5116..6138)
                     /locus_tag="VUX16_001930"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET8124831.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAQFKNGQWNQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVIRANEEYVPPYGTGGTLYLRPLLIGIGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTDFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPVEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTCKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6273..8744)
                     /gene="parC"
                     /locus_tag="VUX16_001931"
     CDS             complement(6273..8744)
                     /gene="parC"
                     /locus_tag="VUX16_001931"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET8124832.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGRRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDLFSTEVEENDQTLLVQSNKGTIYENRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLKEVFTEAK"
     gene            complement(9164..11107)
                     /gene="parE"
                     /locus_tag="VUX16_001932"
     CDS             complement(9164..11107)
                     /gene="parE"
                     /locus_tag="VUX16_001932"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET8124833.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLVAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRREWIEDNVKFTLEEATVF"
     gene            11243..11884
                     /gene="plsY"
                     /locus_tag="VUX16_001933"
     CDS             11243..11884
                     /gene="plsY"
                     /locus_tag="VUX16_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET8124834.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3417 a         2693 c         2092 g         3692 t
ORIGIN      
        1 aaaaatccct tgtttagtaa acaaaggatt ttgtgaattt tcaatttgat taaagttcga
       61 tatcaccaaa caaatcagcc attgaaaatc ctgtttgtgt ttctggaagt tcgaaatcac
      121 gcttttcttg acgtcttgga cgacgtggac gagcagcacg tttttcttct ttttgtcctt
      181 cttcttgggc tggacgttct tcaagagctt taatagaaag tgacacgcgt tctgcatctg
      241 cgttaacttc aagaacttta acttgaactt cttgaccaac tttaagagct tcttttggat
      301 tttcaatccg tttgtgtgaa atttgtgata cgtgaacaag tccatcgata cctggcaata
      361 cttcaacaaa tgcaccgaag tcagtcaaac gtttaactgt tccttctact acatcacctt
      421 tagccaattt ttgctcaacg ccatcccatg gtcctggtac tgttgcttta agtgaaagtg
      481 atacacgtcc ttcttcttcg ttaagatcaa ggattttcac ttcaatttct tcaccaacag
      541 ttacaactga ttttggtgat acgttacgtt catgtgacaa ttcagtcaag tgaaccaatc
      601 cgtcaacacc accaaggtcg atgaaagcgc cgaagcttgt gatacgagca actttaccag
      661 ttacaacatc accaacagcc aatttaccga atacttcagc gcgagctgct gcagtagctg
      721 cttcaacaac ttcacgacgt gaaaggatga agcggttttc tttagcgtta acttctttga
      781 ttttagtatc aaattcttga cctacaaaac gctcagcgtt acgtacgaaa cgagtatcca
      841 acattgaagc tgggataaat ccacgaacac cttcaaattc tactgaaagt ccacctttaa
      901 cggcacgcgt tcctttaaca gtaacaactt cttcttcgcg accaacaagt ttgtcccatg
      961 ctttgcgagc ttcaaggcgt tttttagata caaggtatgt aactgtatca gtatctttac
     1021 caactacttg acgaagtaca agaacatcca atacttctcc tactttaaca aagtcattga
     1081 tatctgcatc acgatcgttt gtcaattcgc gaagagtcaa gacaccttca acaccagttc
     1141 cagagattgc aacgttagct tgagtcgcat caactgtcaa tacttcagca ctaacaacat
     1201 caccagtctc aacttgacta acgctattta gcaaatcttc aaattcgttc atctaaaaaa
     1261 tcctccaaca atcaagtttt tcttaaactt gacatactta taattttttt cctaagcacc
     1321 cgcaaggaca tgtttatatc attcacgtct ttcaattata aaaataaaat accctaagat
     1381 attttgcttt ttatcttgat tattacctaa gaactggggt agctggattc gaaccaacgc
     1441 atgagggagt caaagtccct tgccttaccg cttggctata ccccattaat gaaatggaga
     1501 gagagggatt cgaacccccg aacccgaagg agcggattta cagtccgccg cgtttagcct
     1561 cttcgctatc tctcctacaa tcaacatgga ctattatatc atgaaaattt caaaaaaaca
     1621 agacttattt tgctaaatta taattttcaa tcaaaatttc cacagctttt tccaattttt
     1681 tataaaaact atcgacattc ccattcttta taatggcaaa ttgtccgtct aattcggcaa
     1741 tttctccgat aactttttta ccgatagtca atgtataacc ttcaaaactg tctttaccaa
     1801 cattaacttt ggcatccgct acttgaattt cgattttttt atctttcttg ctcatttcat
     1861 acctctcttc actttttcta ttttacaaga aaatcctaaa actagcaaga aaaaactcta
     1921 tatcaggctt ctctgatata gagttttatg taaacaacct caatcgattt agcatagtta
     1981 atagttagta aacaagcata attgactatc ctttttaggt tatcagtgag tctcaccgcc
     2041 tactaactgc aaatccttat ctttgtagtc tacaatagct tcaatagcta cctctatgcc
     2101 tcttacaata tcacatagac tcattcctgc agtattcggc ttatttacta cttgttccat
     2161 catatatgga atatgcatga aacctgctct catattaggg aattttttat ccactaaata
     2221 aagagcttgg tacatcaaat gattgcaaac aaaggttcct gcactattgg atacaactgc
     2281 cggaagtccc tgttttttga tagcttgtac catcgctttg ataggtaaac tacttaaata
     2341 ggccgatgct ccatcaatac gaatcggtgt atcaattggt tgattgcctt cgttatcagg
     2401 tatgcgagca tcatcttgat taatagccac tcgttcaggt gttaagccga tcctgccgcc
     2461 tgcttgtcca atacaaagta caacatctgg ttgatatcgt aatatttctg cctctaaaac
     2521 ttctgacgac ttataaaaaa ccgttggaat ttctacccag cgaacttcag ccccattaat
     2581 ctcagatggt aataatttta cagcctccaa agctggatta atcttttcac ctccaaaagg
     2641 attaaaacct gtaaccaata ttttcatttt attttccttt actaaaatgc gagaaagtac
     2701 attaagaata tgtgaataac aatcattact agagcaacac ctgcttgagc ctttataacg
     2761 ccattctgat ctttcatatc catcaatgct gctggtagag cgttaaaatt agcagccatt
     2821 ggggtcaata aggtcccaca ataacctgct gtcatggcaa gagcaccagc cacaattgga
     2881 ttagctccca gagcaaatac aaagggaact ccaacacctg ctgtaataac ggtgaatgct
     2941 gcaaaagcat ttcccataat cattgtgaat agaaccattc caagaacata ggccaaaact
     3001 cctataaagc gactatctga aggaacaata ccgctaatca gatgagagat aacatcacca
     3061 acacctgcta cagtaaaaat agcccccaaa gcccctaata attgaggaac aatcccactt
     3121 gttgaaactt gctgagtcat tcgattattt tctgataaca gactcttagg gtgactattg
     3181 gtaatcacaa gaacagaaat tgtagcaaac aaggcggcaa ggctaatcga aatcttgcta
     3241 aattctggaa tcatttgcgc taagaccaac gcaagtattg ccatcagcat aactggaata
     3301 aaaattttat ttttcaacct gttagattca atattggctt tcatttcatc taaggatggc
     3361 aaggttccga tacggacttg cttaaacaat gttaacagcg ataataggat tacaataata
     3421 ccaatactca tatttggcat ataggaacca cctataaacg taatagacaa tagagtccaa
     3481 aatgcagatg tcccaagtcg aactgggttt gttttatctt tataactaca ataggctgta
     3541 tggagaaatt gacaaccaat cacaatatag gtcaactcta atagttgctt tgccaactct
     3601 gtcatttttg ttctcctccc ctagtctttt ttgatatcaa ttttttatca aataaataat
     3661 tgtaaatccc tactacaata agtgttataa cagcaacaat aatagatgta gaagcaatcc
     3721 ctgcataatt gctttcatag cctaactgat ctaatgttcc ccctatcaag aggactcccc
     3781 cagcacctac aaacgtattt tgagcaaaga aatttccaaa attttcattc gcagccgcac
     3841 gcgcttttat tgtctcatct tcaacctctg ttaactttct acctaattga gactctgcag
     3901 ctgcttctcc cataggttga accaaaggtc tgacaaactg agggtgtcct cctagacgaa
     3961 ttgaaaagaa accagctaac tctcgaataa agaaataaac tgtatagaag tttccaactg
     4021 tcagaccttt aatctttcga atcaaatcga ttgatcgttg cttgagtcca aaggtttctg
     4081 acagccccac aagaggcaag gtaaccataa aaatcgtgag cactcgctga ttgctaaatt
     4141 cttttcccaa aatctccaaa aattcaacga gagaaacacc tgaaactaaa gctgtaacca
     4201 aaccagctaa gactactgtt gcaattgtat caaattttaa aataaaaccc acaacaataa
     4261 ttgctattcc tattaatcta atccactcca tatcaaactc ctttatattc aaaatgacag
     4321 tatttttaaa attttatcaa gatcaatacc attccttatt taatgtgttt ttctagttct
     4381 ttttggtatt tgctattgga ttccaatttt tctttttgcc attttttaaa aacctagtta
     4441 tattcttttg ttgtaacaat atctttttgc aatttcattc ctttaaagat atatggatcc
     4501 cccttaatac caacttgtga gtatggtttt gagaatggta ctacgttact tacaactgga
     4561 gaaccaccaa atgaagctgt tggcatcaat aatgaactat ctgtcgacca agcttgagct
     4621 ttggcatatt tttcatatct cttctctagg tcagtagtct cagaaacagc atcttctaac
     4681 aatttcttat atttatccaa accagattta gctacaacat ccttatcttt tcctttcgta
     4741 ataccaaggt gtttcatggc agaaccagat tttggatcca taatattcaa gtaagacgct
     4801 ggttcttgat agcttggagc ccatcctgta ctgttcaaat catagtcttt ttgagaagga
     4861 gcaacattgc cgtatttatc attttccatc aagccatcaa taacatttcc aataacgtct
     4921 gtcgtcgatg ttcgagtcgc tatactgtag tccaatgatg ctggatctac tgcatagaca
     4981 taagaaaatg ttgtcggtgc atctgcttct ttatcagttt ttccacaagc cactaaaata
     5041 gctgtcgtgc tcaggaccgc tcctgctgtt aagagtcact ttttcgattt cataaaaaat
     5101 ctattttggt ttattttaat ctacttttac aatccaacct tctggcgctt caatatcgcc
     5161 aaactgaata cccgtcaatt cattatataa tttacaagtc acaggaccta cttctgtttc
     5221 actatagaat acatggaaat catcaccgtg ttgaatacct ccaattggag aaataaccgc
     5281 tgctgtacca caggcacctg cctctacaaa acggtcaaga ttatcaattg gaacatcacc
     5341 ctcaacagga gttaatccca agcgatgttc tgccaaataa agcaaggaat acttggtaat
     5401 agatggcaag atagatggac tcaatggtgt tacaaattca ttatcagctg taattccaaa
     5461 gaagttagct gatccgactt cttcaatctt tgtatgagtt gatgggtcca gatagataac
     5521 atctgagaaa tgacgtgact tggccatttt tcctggtaag agacttgcag catagtttcc
     5581 accaacctta gccgcacctg taccatttgg tgctgcacgg tcgtattcat cctgaatcaa
     5641 gaagtcggtt gggaccaaac cacccttaaa gtaatttcca actggcatag caaagatagt
     5701 aaaaatatac tcctctgctg gttttacccc gataatatct ccgataccaa tcaaaagagg
     5761 gcgaagatag agggttccac ctgttccgta tggtggtacg tattcttcat tcgcacgaat
     5821 aactgcttta caagcttcta caaacatgtc tgtcggaact tgtggcatca agagacggtc
     5881 acatgtacgt tgcaggcgtt tggcattttc gtcaggacgg aacagttgaa cactgccatc
     5941 cttagtacga taagctttca aaccttcaaa tgcttgttga ccatagtgaa gacttggaga
     6001 agactctgaa atatgcaaag ttgcatcctc tgtaagttct ccttgattcc attgtccatt
     6061 tttaaactga gcaagatagc gataaggtaa tttcatatag gaaaaaccga ggttttccca
     6121 atcaatcgtt actgtcatat tccactcctt attctaaaaa cctatttctt atattctaca
     6181 ctatttttct aaaatagcaa gtctgttttg taattttcag aaaatttctc caataacaag
     6241 aaccagctct tagaactgat tcttcatttc acttatttag cttcagtaaa tacttcttta
     6301 agataagcgt caaaaacttc ttcatctgaa atcgtgtcag aaatgaagct tccgttgcta
     6361 gtcctttctg acaggttcaa gtcttgcaat ctgttttcat agattgttcc tttgttggat
     6421 tgaacaagca gcgtttggtc gttctcttct acttctgtac tgaagagatc gccaacaaat
     6481 ccttgctctg caactgctcc tgccaagaag acacgatgcg gtttgttttt caactcacgc
     6541 aagacttgta atcctcgttt ggcacggctg gttgctagaa tttcctcaat ggaaacacgt
     6601 ttcaagcttc cacgctgggt caagaggtag aaggacgaag tattacagat aaagccagat
     6661 tggaggacat catcttcttt caaattcata gccttgacac ctgctgcctt agcaccgaca
     6721 accggaacct cttcgatatt gaaacgcagg gcataaccat tttgactaac caagacaaca
     6781 tcatctagtt taatcggagc cactgctaca atctgatctg tatcgtcttt gagcttagca
     6841 tacttgacag acttagatct ataggtccgc catggagtga attcttttcg ctctacccgt
     6901 ttgatttgac caaggcgagt cactgcaaag taggttgtcg catcgtcaaa ctgatccagt
     6961 acttccacat aaaggatttc ttcattcgtt tcaaagtttg tgatggtttg gctcagatgc
     7021 tctccgatgt ccttccaacg aatatctgcc aactcatgga ttggtctgta gatgacattt
     7081 ccaagacttg tgaacatcaa gaggtgctgg gttgtcttgg cagattgaac aaaaatcaaa
     7141 cggtcatcat cacgcctgcc aatttcttcc aaggtggaag ccgcaaagga acgtggactg
     7201 gtacgcttga tgtaacctgc cttggtcacg ctgacgtagg tatcttcctc agcgataaga
     7261 ctagctgtat caatctcaat tgctttcgca gtgtcttcta aagaactcaa acgaggagtt
     7321 gcaaatttct tcttgacctc acgaagttct ttcttcatga gattgtacat agtcctttca
     7381 tcaccgataa tagccgccag catagcaatc ttctcacgaa gctctgcttc ttcttcctgc
     7441 aagacaacca catcggtatt ggtcaaacgg tacagttgca aagttacgat agcctcagcc
     7501 tgttcttccg taaaatcata gctaactttg aggttttcct tggcgtccgc cttattctca
     7561 gaagcacgga taagagcaat gacttcatcc aaaatcgaaa tcacacgaat caaaccttcg
     7621 acgatatgga gacgtttctc agccttttct ttgtcaaagc gtgaacgcgc caaaatcact
     7681 tctcgacggt gagcgatgta gctagacagg attggaacaa tcccaacctg acgaggtgtg
     7741 aaattgtcaa tcgccaccat attaaagttg tagttgattt gtaggtcggt gtacttaaat
     7801 aagtaattga gaacaagctc agtattagcg tctttcttaa gttcaatagc gatacgaaga
     7861 ccatcacggt cagactcatc acgaacctca gcaatcccag ctaccttgtt attaacacga
     7921 acatcatcga ttttcttgac tagattggcc ttattgattt cataaggaat ctcagtaata
     7981 acgatttgtt ccttaccacc ttttagcttt tcaatttcag tcttggaacg aacaaccacg
     8041 cgccctttcc cagtctcata agctttcttg atttcatcac gaccctgaat aatagcccct
     8101 gtagggaagt ctggtccagg taagaattcc atgagtttat caatctttgc agttgggtgg
     8161 tcaatcatgt aaactgcagc atctatgacc tcagctaaat tatggggagg aatgtctgtg
     8221 gcataaccag ccgaaatccc agtcgaacca ttgaccaaga ggtttggaaa ggctgctggc
     8281 aagaccgttg gttctttctc cgtatcgtca aagttccatg caaaaggaac tgtctttttc
     8341 tcgatatcct gaagaaggta gcctgcaatt tcagacaaac gtgcctcagt ataacgcata
     8401 gctgcaggag gatctccgtc catagaaccg ttattaccgt gcatttcaac tagaatctca
     8461 cgatttttcc agttctgtga catacgaacc atggcatcat agatagaaga atccccgtgt
     8521 gggtggaaat tccccatgat gttcccgact gacttagccg acttacggta gctcttgtca
     8581 aaagtattgc tatccttatt catagaataa agaatacggc gctgaaccgg cttcaaccca
     8641 tcacgaatat ctggcaaagc ccggtcttga ataatgtact tggagtagcg accaaagcgc
     8701 tctcccatga tgtcctccag ggacatgttt tgaatgttag acataagata caaagcccat
     8761 aaaataccaa gtaaaaatag aaaattcttg aagtaagcaa actcacaaga gaatttatct
     8821 ttttcacaca gtatctaggg cgtgttcaac tcctttcaaa gaatgtagag taggttttta
     8881 tgcagtaaaa gatattttac gggaattcct cccgtgttca gttacgataa gtaaccaaac
     8941 tatcctgttt gtatttttca atatgaaaat ctggttttcc aaaattagtc ttagtttgtg
     9001 tcttagccgc tcccttaagc gcctctttga gataagcact catagcagat tcttcattaa
     9061 taatcctgca attttttcaa accaagattt tcaaactgct ttttcacata gtcattcaca
     9121 tccgactcta atttccagtt tactaacata ttattttctt tcattaaaac actgtcgctt
     9181 cttctagcgt aaacttgaca ttatcttcaa tccattcacg gcgtggttct accttatctc
     9241 ccatgagaac attgacgcgg cgttcggcgc gcgctaaatc ttcaattgtg acacggatga
     9301 gggtacgtgt ttctgggttc atggttgttt cccagagctg gtccgcattc atctcaccaa
     9361 gtcctttgta tcgttggagg gtagcgcctt taccgaactg tttacggagt tcttctagtt
     9421 ctccgtccgt ccaagcgtag gccacttctt ctttcttgcc tttacctttg gacatcttgt
     9481 aaagaggtgg gagggcaata tagacatgac ctgcctcgac tagcggacgc atgtaacggt
     9541 agaaaaatgt caagagcaag gtctggatat gggcaccgtc ggtatccgca tcggtcatga
     9601 taatgatctt atcatagttg gcatcttcaa tagagaagtc tgctccaaca cccgcaccaa
     9661 tggtataaat catggtattg atctcttcat ttttgaggat atccgccatc ttggccttgg
     9721 ctgtattgac aaccttacca cgaagaggta gaatagcctg gaacttgcgg tcacgacctt
     9781 gtttggcaga accaccggca gagtccccct caactagata gagttcattc ttagcaggat
     9841 tcttagattg ggctggggtc aatttcccag acaacaagcc cttatctttc ttgtttttct
     9901 tcccatttcg gctctcatca cgcgccttac gtgctgcttc acgagcatca cgggccttga
     9961 tagccttgcg gatgaggtta gaagctaatt ccccattttc cataaggaaa aaggtcaact
    10021 tatcagccac tattccatcc acaactgggc gagctagggg gcttcctagt ttatccttgg
    10081 tctgtccttc aaactgcaag tgttcttcag gaactaagat agaaagaacg gccactagtc
    10141 cctcacgata gtctgaacct tcaaggtttt tatctttttc cttaagaaga cctgttttac
    10201 gtgcatagtc attcatgacc ttggtaatgg cagacttgag tcctgtctcg tgcgttccac
    10261 cgtccttggt gcgaacgtta ttgacaaagg atagaatgtt atctgagaat ccgtcattgt
    10321 actggagggc tacttccact tgaaaaccat tgtcttcccc ttcaaagtaa agaactggcg
    10381 tcaagatttc cttatcttcg ttgagataag aaacaaaatc ttgtactcca ttctcatagt
    10441 ggaactcaat cgcttcatct gttcgcttgt ccgttaaaga caaggtcaca tttttcaaga
    10501 gaaaggctga ttcattaagg cgctctgaaa tggtattgta cttgaaatct gtcgtagaaa
    10561 agatagtcgc gtcaggcata aaagtaactt tggtgcctgt tttagacttg ggtgctgtac
    10621 cgattttctt caaagtcgtg acaggttttc caccattttc gaaacgttgc ttgtaaactg
    10681 cgccatcacg ggtaatttca acttctaacc agctagaaag ggcgttaaca acggaagaac
    10741 ccactccgtg aagtccacct gatgtcttat agccaccttg accgaatttc cctccggcat
    10801 gaagaatggt aaagataacc tcaacagttg gaattcccat agcgtgcata cctgtcggca
    10861 tcccacgtcc atggtcttga accgttagac taccgtcttt attgatagtt acatcgatac
    10921 gatcaccaaa cccagacaag gcttcatcga ctgcattatc aacgatttcc caaactaggt
    10981 gatgaagacc agcgccatcg gtcgatccaa tatacatccc tggacgtttt cggaccgcat
    11041 ccaacccttc tagcacctga atagcatcat cattataatt gttaatattg atttcctttt
    11101 ttgacacaag gaacctccta ttcgttcatc tttactattc tacaggtttt ccaaggattt
    11161 tgcaaaattt ttctttctcc gatgtgacaa tttcagcaga gattctctgc ttttctttcc
    11221 caattcatga tataatagga gtatgattac aatagtttta ttaatcctag cctatctgct
    11281 gggttcgatt ccatctggtc tctggattgg acaagtattc tttcaaatca atctacgcga
    11341 gcatggttct ggtaacactg gaacgaccaa taccttccgc attttaggta agaaagctgg
    11401 tatggcaacc tttgtgattg actttttcaa aggaacccta gcaacgctgc ttccgattat
    11461 ttttcatcta caaggcgttt ctcctctcat ctttggactt ttggctgtta tcggccatac
    11521 cttccctatc tttgcaggat ttaaaggtgg taaggctgtc gcaaccagtg ctggagtgat
    11581 tttcggattt gcgcctatct tctgtctcta ccttgcgatt atcttctttg gagctctcta
    11641 tcttggcagt atgatttcac tgtctagtgt cacagcatcg atcgcggctg ttatcggggt
    11701 tctgctcttt ccactttttg gttttatcct gagtaactat gactctctct tcatcgctat
    11761 tatcttagca cttgctagtt tgattatcat tcgtcataag gacaatatag ctcgtatcaa
    11821 aaataaaact gaaaatttgg tcccttgggg attgaaccta actcatcaag atcctaaaaa
    11881 ataaaacgcc agtt
//
LOCUS       DAVDZK010000054        11549 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVDZK010000054 DAVDZK010000000
VERSION     DAVDZK010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11549
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.055"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            437..1147
                     /gene="deoD"
                     /locus_tag="VUX16_001934"
     CDS             437..1147
                     /gene="deoD"
                     /locus_tag="VUX16_001934"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET8124835.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1170..1694)
                     /locus_tag="VUX16_001935"
     CDS             complement(1170..1694)
                     /locus_tag="VUX16_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET8124836.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1747..1983)
                     /locus_tag="VUX16_001936"
     CDS             complement(1747..1983)
                     /locus_tag="VUX16_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET8124837.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(2051..2971)
                     /locus_tag="VUX16_001937"
     CDS             complement(2051..2971)
                     /locus_tag="VUX16_001937"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET8124838.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGSLNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWSSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3161..3564
                     /locus_tag="VUX16_001938"
                     /pseudo
     CDS             3161..3564
                     /locus_tag="VUX16_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3780..4361
                     /locus_tag="VUX16_001939"
     CDS             3780..4361
                     /locus_tag="VUX16_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET8124839.1"
                     /translation="MYYAENPDTAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4358..5635
                     /locus_tag="VUX16_001940"
     CDS             4358..5635
                     /locus_tag="VUX16_001940"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET8124840.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTIAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5653..6315
                     /gene="deoC"
                     /locus_tag="VUX16_001941"
     CDS             5653..6315
                     /gene="deoC"
                     /locus_tag="VUX16_001941"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET8124841.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGAGEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6302..6691
                     /locus_tag="VUX16_001942"
     CDS             6302..6691
                     /locus_tag="VUX16_001942"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET8124842.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6781..7833
                     /locus_tag="VUX16_001943"
     CDS             6781..7833
                     /locus_tag="VUX16_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET8124843.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDIANKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7977..9512
                     /locus_tag="VUX16_001944"
     CDS             7977..9512
                     /locus_tag="VUX16_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8124844.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVVENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEITGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RVASELVPAAALSGGNQQKAIIAREIDRVPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            9505..10563
                     /locus_tag="VUX16_001945"
     CDS             9505..10563
                     /locus_tag="VUX16_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124845.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGLVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLSELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGASLAV
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10566..11522
                     /locus_tag="VUX16_001946"
     CDS             10566..11522
                     /locus_tag="VUX16_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8124846.1"
                     /translation="MSITTLLTLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGCLFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYI
                     AIAFSFLAWFILFKTRFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPTVYLQIAPYVLTTLVSAAFFGKAVAPKADGINYIKSK"
BASE COUNT         3286 a         2081 c         2640 g         3542 t
ORIGIN      
        1 tggtttgaag agattttcga agagtataaa cagaaaggta gagtgcgtgt tctaatttga
       61 acacgagtag aaaacttttc taaaaacaaa aacgaaagga tgggtaaact gtattcgcta
      121 aactgaatac gggcgactct cctctaaatc aaaattaaga aagaaaggaa ttgaccccac
      181 cctaaaagca gtgggaaaaa gatagttggt ctagcgagca tcgctcactg cgcccaactc
      241 ctattttccc ttcgcttttt gacgggtttg gtatctttct caatataaaa tataaaataa
      301 agaaaggtag agcgtgtgtt ttgatttgaa cacgagcgga aaactcggaa aatagataat
      361 ctgactgaaa aatcaggatt tctcgtcagg ttcctaattt tcagtcgttt tcttctcgct
      421 ctttgtatca taaattatgt ctatccatat tgctgctcag cagggtgaaa ttgctgataa
      481 aattcttctt cctggggatc ctcttcgtgc taagtttatt gcggagaatt tccttggtga
      541 tgctgtttgt tttaacgaag tgcgtaacat gtttggttac actggtactt acaagggtca
      601 ccgtgtatct gtcatgggaa ctgggatggg aatgccatct atttcgattt atgcgcgtga
      661 gttaatcgta gactacggtg tgaagaaatt gattcgtgtg ggaactgcag gttctttgaa
      721 tgaagaggtt catgttcgtg aattagtttt ggcgcaggcg gctgcaacca actcaaacat
      781 cgttcgtaat gactggccac agtacgattt tccacaaatt gctagctttg atttgcttga
      841 taaagcctac catatcgcca aaaaacttgg tatgactact cacgttggga acgttttgtc
      901 atctgatgtc ttttactcaa attactttga aaagaatatc gagcttggta aatggggagt
      961 caaggctgtg gaaatggaag cagcagctct ttactatctt gctgcccaat accatgttga
     1021 tgcgctagct atcatgacca tctctgatag cttggtcaat ccagacgaag acacaactgc
     1081 agaagaacgt caaaatacct tcactgatat gatgaaggtt ggtttggaaa ccttgattgc
     1141 agaataatta tagccaaaaa ggaagccctt tatgaattgt aggacttcct tttcttatcc
     1201 agaaattgat ctagctctct ctgatttcga agaatagtga ctttatgtga atattcttgg
     1261 caaagttttt ggtaattttc tttttgagtt ttgctacgcc catcccaaag aatccatctg
     1321 ataaactccc actcaaagcg ttcagggcaa tctgccgcca tactttctct gacttttcca
     1381 cggtatttaa gataacgctt aaaggctcta aagagacagg tcaatggcga aaaattgaga
     1441 aagatgattt ggtcagcttc ttgcattcgt tcttggtagt agcaccaaga ataattacca
     1501 tcgatgaccc aagctttatg cttggtgaga aagtttttta tctcggttaa catccattcg
     1561 cagtcactgt cttgccaacc aggttgaaat tggagtgtgt ccatgtgcag ttttggaatg
     1621 gagtagtagt tagataactt ttctgctaga gttgacttac cagaaccaga atatccgata
     1681 attgcgattt tcattttcta ccttttccta tttggagaca aaaaaacagc ctctatggac
     1741 tgtttcttat ttagcaagtt tagctgaaag acgagcttta tcgcggcttg ctttgttttt
     1801 gtgaatcaaa cctttagttt ctgctttatc tatagctgag ctagcagcac ggaaaagttc
     1861 ttcagatggg tttgcttcga aagcttttat agcagtacgc atagctgatt tttgagctga
     1921 gttcttttcg ttttgtttaa cgttcaattc agcgcgtttg atagctgatt taatgtttgc
     1981 caatgttctt acctccatat ttactaacta taccattata tatgaaaact tacgttttga
     2041 caagggaaaa ttactttttt aagtaaattt catcgatttc atggttcttg cttttatgaa
     2101 gaatcacttc tgcacgattt ctggttggtt caatataatt ttgcagattt gtgaggttga
     2161 tactgctcca gacctgatgg gcaaaggact ccacttcccc aatcggcatc tgagtaaaac
     2221 gataatagta gctatcaggg tcgttttggg ctaggctcag cattttcaag aaacggtcca
     2281 gataccaact ttcaatatca tccactccag catctacata gatggaaaag tcaaagaagt
     2341 cagtgatata gagacgatcg ttttgtggat tttgaaagac attaattccc tcaacaatta
     2401 caaaatcagc agctttgaca ctttgtttct tttcgggtac gatgtcgtaa acttcatgag
     2461 aatagacagg aatatctaca tcttgtccat ttttgatgcg gtccaagaag ttgagaagag
     2521 cttccatatc atagctttca ggaaatcctt tacgatttaa actcccctgc tcaatcaagg
     2581 tttgattggg atagagaaaa ccatcagttg taaccaactc aaccgtagca tctgtaaacg
     2641 tacgggacag taggatttga agtaggcgac tggttgtgga ttttccaacg gcaacactcc
     2701 cagaaacccc aataataaaa ggttgagatt tactttcacg ttggaggaaa attccttttg
     2761 aaaaggctaa atcttcctta gttcgcttgt aaatctgaat cagatgagcc aaggggagat
     2821 agatatctgt aacgtcttgg agactgattt ggtcattaaa actcttgata gattccaatt
     2881 cttcttctgt caaaggaggt gttgtcttgc gatgtaaaga ttgccaagtc tggcggctga
     2941 ttttttcaaa atgtaaaaat tcgttggtca tttgttttcc cctagatatt ttgtctatca
     3001 taccataaaa agctaaaaaa ataaagcggt ttcttgaatg tggtaagtca atgatatata
     3061 gtataagtga tcaatttatt gatgaaatag gagatagatt ctactgattt ataagcttat
     3121 aaaggaggct ttttagttca caacttatag gaggtgtact atgaaaatct taaaacgtta
     3181 catattggaa ctctgtttta ttttaagttt tgctttacct tttataaaag gaaccaatgc
     3241 agataatggt agatgctttg tggaaaccta ttacggtttt acttttttga tggaacatgc
     3301 tattgtaaca gctgtcttta tctgttcgtt cttaattgct ttcttactaa aaaacgatgg
     3361 gcgaaatgga ttgctgctgg tagttattgc tttttagtcc tatggattgc gacagagggt
     3421 tatttcttcc atatgtcacc agaagatttg atacgacttt ggacaagttt ggaaatcctg
     3481 acacaaacgt atcagttggg cttttatcta aacattttgt taggaatttt gttgatgatt
     3541 aagcatttga aggttaagca atagaaataa taatctgcct gattatagat gataaacttt
     3601 ttgtttttat ctggactgtg atatttatag ttctaaatgg tttattattt ataagtgttg
     3661 aaagagattg aagaaaatgg cttcgtgact cgctttcttc ggtctttttc gttttattat
     3721 caatttgtaa acgatttaca atttgagtca aattatggta aaatagtgtc atgagtaaaa
     3781 tgtattatgc agaaaatcct gacactgctc acgacattca tgagttgaga gtagagttgt
     3841 tgggacaaaa aatgaccttt ttaacggatg cgggtgtttt tagcaagaaa atagttgact
     3901 ttggaagtca actattgctc aagtgtcttg aggtcaacca aggagaaact gtccttgatg
     3961 taggctgtgg ttacggacct ttgggtttgt ccttagctaa ggcttatgga gttcaggcta
     4021 ctatggttga tatcaacact cgtgccttgg atttagctcg gagaaatgct gaaaaaaata
     4081 atgcaaaagc gacgattttc cagtccaaca tctatgaaca agttgaagga cattttgatc
     4141 atgtcatttc caatcctcct atccgtgcgg gcaagcaagt cgttcatgaa atcattgaga
     4201 aaagtaaaga tttcttggaa actggtgggg atttgacaat cgtcatccag aaaaaacaag
     4261 gggctccaag tgctaagtcc aagatggagg atgtgtttgg taattgtgaa atccttaaaa
     4321 aagacaaagg atactatatc cttagaagtg tgaaagaatg agagcagttg atttaatcca
     4381 aaaaaaacga gacggtcaag aactgacttc aagtgaaatt gaatggctgg tagaaggcta
     4441 tgtgtcagga actgttcctg attatcagat gtctgctttt gctatggctg tttattttaa
     4501 aggaatgacg actcgtgaaa tttctgattt aacgatgaat atggttaaga ctgggcaaga
     4561 gtttgacctg tcagccattg atggtgtgaa agttgacaag cattctactg gtggtgtcgg
     4621 cgataaggta accttgattt tagctcctct tgttgctagc ttcggtgtgc ctgtagcaaa
     4681 aatgagtggt cgtggtcttg gccatacagg cggaacaatt gataaattgg agtccattag
     4741 gggctatcaa gtagaacgta gtcaagagga ttttattcgt caggttcagg atattggagt
     4801 atctgtcatt gggcaatcag accagctggt caaagcagat aagcttctct atgcccttcg
     4861 tgatgtgacc gcaactgtcg acacgattcc tttgattgcg agttcggtga tgagcaagaa
     4921 aattgcggca ggggcggatg ctattttgct agacgtgact gtcggtgagg gtgccttcat
     4981 gaagacggtt gatgaggcgc gtgagttggc tcaaactatg gtagatcttg gtaaggttgt
     5041 tggacggaag acaatagcag tgattacgga tatgagccag cctttgggac gagcgattgg
     5101 aaatcgtctg gaaatccttg aagcattgga gattttgcaa ggtcaaggac gtcaggatat
     5161 tacccacttt atttgtgaat tggctcaaat tatgcttggt ttggcaaatg ttaacaagac
     5221 tgttgaagaa gttcaccaac atcttgagaa tggtcaagca ctggctaagt ttgaggaaat
     5281 ggtgcaagcc caaggtggag acttggaaga cctctatcgt cctgtaaatg tagctcatgt
     5341 ggtggaaatc cctgctcagg aaacgggtgt catttcagct cttccagcta tggactttgg
     5401 tctttatgcc atgaggctgg gtgctggtcg tgcagttaag tctgatgcct tggactatga
     5461 aacaggaatt gtttttgaaa agaagattgg agactccgtt caaaagggtg aaattgttgc
     5521 aaaagtatac acaaatgaaa aaattccacc tcaactagtt acagatttcc aaaaatgtgt
     5581 taaaataagt gatgaagtga aaaaaatccg tgaaattgta gaaatcatct cctaaatgga
     5641 gggaaaaccg aaatgaaatt aaataaatat atagatcata cgcttttaaa acaagatgca
     5701 aagaaaaaac aaattgatag tttgttgtct gaggctagag agtatgactt tgccagtgtt
     5761 tgcgttaatc cgacctgggt tgaacatgct aaaaaaggac ttgaaggcac agatgttaag
     5821 gtttgcacag tagtaggttt ccctttggga gcaacaactt cagccgtgaa agcatttgag
     5881 acaaaagaag ctatccaaaa tggtgcaggt gagattgata tggtgatcaa tgttggagct
     5941 ctcaaatcag gtaatttagc cttggttgag tcagatattc gcgcagtagt ggaagcaagt
     6001 ggtgataagt tagtgaaagt cattattgaa gcttgccttc tgacagacca agaaaaagtt
     6061 gttgtttgcc aattggccca aaaagctggg gctgactttg tcaaaacatc tactggcttt
     6121 tcaactggtg gtgctacgat agcagatgtt acattaatgc gtgaaacagt tggatctgat
     6181 atgggtgtca aggccgccgg tggagctcgt tcttatgcag atgctcttgc ctttgtcgaa
     6241 gcaggtgcga cccgtatcgg aacgtcagct ggggtagcta ttttaaaagg agaattggca
     6301 gatggcgact actgagttga ttgaactggc aattgaaacc agcaaacatg cctatgtccc
     6361 ctattctcac tttcctatcg gagcagtttt agtagctaaa gacggaagtg tttacacggg
     6421 agtgaatatc gaaaatgcta gctatccttt gaccaattgc ggtgagagaa cagcagtttt
     6481 taaggctata tctgaaggcc aaagagaatt ttcagaattg attgtctatg gtcaaactga
     6541 aaaaccgatc tcgccatgtg gtgcttgtcg ccaagtaatg gtcgaatttt ttgaacaaga
     6601 tttaaaagtg accttagtcg caaaagataa atcgacggtc gagatgacgg tcggggagtt
     6661 acttccatac tcttttacag acttaaacta gtctgagtcg ctctttgagt ggcacggtcc
     6721 ttgtggccaa ccaatccata cttgcaacat cgttgcacat cttatttagg aggttcagta
     6781 atgaacaaga aacaatggct aggccttggt ctagttgcag tggcagcagt tggacttgct
     6841 gcatgtggta accgctcttc tcgtaacgca gcttcatctt ctgatgtgaa gacaaaagca
     6901 gcaatcgtca ctgatactgg tggtgttgat gacaaatcat tcaaccaatc agcttgggaa
     6961 ggtttgcaag actggggtaa agaacacaat ctttcaaaag ataatggttt cacttacttc
     7021 caatcaacaa gtgaagctga ctacgctaac aacttgcaac aagcggctgg aagttacaac
     7081 ctaatctttg gtgttggttt tgcccttcac aatgcagttg aagaagcagc taaagaacac
     7141 actgacttga actatgtctt gattgatgat gtgattaaag accaaaagaa tgttgcgagc
     7201 gtaactttcg ctgataatga gtcaggttac cttgcaggtg tggctgcagc aaaaacaact
     7261 aagacaaaac aagttggttt tgtaggtggt atcgaatctg aagttatctc tcgttttgaa
     7321 gcaggattca aggctggtgt tgcgtcagta gacccatcta tcaaagtcca agttgactac
     7381 gctggttcat ttggtgatgc ggctaaaggt aaaacaattg cagccgcaca atacgcagcc
     7441 ggtgcagata ttgtttacca agtagctggt ggtacaggtg caggtgtctt tgcagaggca
     7501 aaatctctca acgagagccg tcctgaaaat gaaaaagttt gggttatcgg tgttgaccgt
     7561 gaccaagaag cagaaggtaa atacacttct aaagatggca aagaatcaaa ctttgttctt
     7621 gtatctactt tgaaacaagt tggtacaact gtaaaagata ttgctaacaa ggcagaaaaa
     7681 ggagaattcc ctggcggtca agtgatcgtt tactcattga aggataaagg ggttgacttg
     7741 gcagtaacaa acctttcaga agaaggtaaa aaagctgtcg aagatgcaaa agctaaaatc
     7801 cttgatggaa gcgtaaaagt tcctgaaaaa taatggatgg aagtcatttc ttaggaagcg
     7861 gccaagggcc gcttttttaa gagttgagac aaagtcattt tgtctcagta aagcttgcta
     7921 ctagacaaac tagcaagttt tattgaaata aaataagact ctgaaaggaa gagcacatgg
     7981 cacacgaaaa tgtcattgag atgcgtgata ttaccaaggt gtttggtgga tttgttgcca
     8041 acgacaaaat caacttgcac ctacgaaaag gtgaaattca tgcactttta ggagaaaatg
     8101 gggctggtaa gtccacgcta atgaacatgt tagcaggcct tcttgaacca actagtggtg
     8161 aaatcgcggt caacggtcaa gttgtcaatc tcgactcccc atctaaagca gctagcttgg
     8221 gaatcgggat ggttcaccag cactttatgt tggttgaagc cttcacagtg gttgaaaaca
     8281 tcattttagg tagtgaattg actaaaaatg gtgtgctaga tatcgctgga gctagcaaag
     8341 aaatcaaggc tctttctgaa cgttatggct tagctgttga cccttctgcc aaggtagcag
     8401 atatctcagt tggagcccaa caacgtgtag aaattttaaa aacactttat cggggggctg
     8461 atatccttat ctttgacgaa ccaacggctg ttttgactcc atcagaaatt gatgagttga
     8521 tggctattat gaaaaatctt gtcaaagaag gaaaatcaat tatcttgatt acccacaaat
     8581 tggatgaaat tcgcgcagtt tctgaccgtg ttacagttat ccgtcgtggg aaatcaattg
     8641 aaaccgttga aattacaggg gctaccaatg ctgatttggc ggaaatgatg gtaggacgtt
     8701 ctgtttcctt taaaacagag aagcaagcct ctaaaccaaa agaagtggtt ttgtctatca
     8761 aagatttggt ggtcaatgaa aaccgtggtg ttccagctgt taaaaatctg tccttggatg
     8821 ttcgtgctgg agagattgtt ggtattgcgg ggattgatgg aaatggtcag tctgaactga
     8881 ttcaagccat tacaggtctt cgtaaggttg aatctggtag cattgagcta aaaggagatt
     8941 caattgtagg cttgcaccca cgtcagatta cagaactaag tgttgggcac gttccagaag
     9001 accgtcaccg tgatggcttg attttggaaa tgatgatatc tgaaaatatt gcccttcaaa
     9061 cctactataa agaaccacat agtaaaaatg gaattttaaa ctattcaaat attacttctt
     9121 atgctaaaaa gctgatggaa gagtttgatg ttcgcgttgc cagtgaatta gttcctgcag
     9181 ctgcactctc aggaggaaat caacaaaaag caattattgc tcgtgaaatt gatcgagttc
     9241 ctgatctcct tatcgttagc cagccaactc gtgggttgga tgtcggtgcc attgagtata
     9301 tccacaaacg cttgattgaa gagcgtgata atggcaaggc tgtccttgtt gtcagctttg
     9361 aattggatga gattttaaac gtctcagacc gtattgccgt tatccacgat ggtaagattc
     9421 aaggtattgt atcaccagaa acaaccaata aacaagaact tggtgtcttg atggctggtg
     9481 gaaacttggg aaaggagaag agtgatgtct aaaaaattac aacaaatttc ggttcccttg
     9541 atttctgtat tcctaggaat tttactcgga gccattgtca tgtggatctt cggttatgat
     9601 gctatttggg gctacgaaga attgttctat acagcctttg gcagtctgcg tgggattgga
     9661 gaaatcttcc gtgctatggg tcctctggtc ttgattggtc ttggttttgc cgttgccagt
     9721 cgagctggtt tctttaacgt cggacttcct ggtcaggctt tggcaggttg gattctcagt
     9781 ggttggtttg ccttatcgca tccagatatg ccccgtccct tgatgattct ggcaactatt
     9841 gtgattgcct tgattgctgg tgggcttgtc ggagcgattc caggtattct tagggcctat
     9901 ctagggacgt cagaggttat tgtaactatc atgatgaact acattgtctt gtatgtagga
     9961 aatgccttta tccatgcctt ccctaaagac tttatgcaaa gtacagattc gaccattcgt
    10021 gttggggcta atgcaaccta ccagacacct tggttgtctg agttgactgg taactcacgg
    10081 atgaatattg gtattttctt tgccatcatt gccgttgcag tcatttggtt catgctcaag
    10141 aaaacgactc ttggttttga aattcgcgca gttggtctca atccacatgc ttcagaatat
    10201 gcgggtattt ctgcaaaacg gacgattatc ctctcaatga ttatttcagg tgccttggca
    10261 ggtcttggtg gtgctgttga aggacttgga accttccaga acgtctatgt tcaaggggca
    10321 tcattagctg ttggatttaa cggaatggcg gttagtctgc ttgcagccaa ctcaccaatc
    10381 ggtattctct ttgcagcctt cctatttggt gttctccaag ttggagcccc tggtatgaat
    10441 gcggcgcagg taccgtctga gcttgttagc attgtaacag cgtctattat cttctttgtc
    10501 agtgttcatt accttatcga acgctttgtc aaaccgaaaa aacaagttaa aggaggtaag
    10561 taaagatgtc tattacaacc ttgctcaccc ttttggtatc ttctatgctg atttactcag
    10621 cacccctcat ctttacaagt attggtggtg ttttctctga acgtggtggt gtggtaaacg
    10681 tcggccttga aggaattatg gttatgggtg ccttttctgg agttgtcttt aaccttgaat
    10741 ttgcagaaca atttggagca gcaactccat ggctatcttt gctagttgca ggattggttg
    10801 gatgcctctt ctctatcatc cacgcagcag cgacggttca tttccgtgca gaccatgttg
    10861 tcagcggtac ggtattgaac ttgatggcgc cagccttggc tgttttctta gtcaaagttc
    10921 tttataacaa aggacaaacc gacaacctaa gtcagacttt tggacgcttt gacttcccag
    10981 tcttggcaaa tatcccagtg attggtgata tcttcttcaa gtcaactagt ctgcttggtt
    11041 atatcgcgat tgccttctca ttccttgctt ggtttatcct cttcaagacc cgatttggtc
    11101 ttcgtctccg ctctgtaggt gaacatcctc aagcagcgga taccttggga atcaatgtct
    11161 acaagatgag atatctagga gttatcattt caggtttcct aggtggaatt ggcggagcga
    11221 tttatgctca atccatctca gttaacttct cggtaacaac tattgttgga cctggattta
    11281 ttgctcttgc tgcgatgatt ttcggaaaat ggaatccaat cggagccatg ctatctagtc
    11341 tcttctttgg gctttcacaa agtttggctg ttatcggttc tcaattgccg ttcctacaag
    11401 gagtgcctac agtttatctt caaatcgcac cttatgtttt gacaactctt gtctcagcag
    11461 ccttctttgg aaaagcagtc gcaccaaaag cagatggtat caactacatc aaatcaaaat
    11521 aagcatacaa aaaaacgtca gtccaatga
//
LOCUS       DAVDZK010000055        11212 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVDZK010000055 DAVDZK010000000
VERSION     DAVDZK010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11212
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.056"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(<1..1035)
                     /locus_tag="VUX16_001947"
     CDS             complement(<1..1035)
                     /locus_tag="VUX16_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET8124847.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANV
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAI"
     gene            complement(1115..1978)
                     /locus_tag="VUX16_001948"
     CDS             complement(1115..1978)
                     /locus_tag="VUX16_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET8124848.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFYNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(1981..3882)
                     /locus_tag="VUX16_001949"
     CDS             complement(1981..3882)
                     /locus_tag="VUX16_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET8124849.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFCQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATVEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
     gene            complement(4308..4583)
                     /locus_tag="VUX16_001950"
     CDS             complement(4308..4583)
                     /locus_tag="VUX16_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET8124850.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(4690..5529)
                     /locus_tag="VUX16_001951"
     CDS             complement(4690..5529)
                     /locus_tag="VUX16_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET8124851.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDIEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKNHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            5670..6518
                     /locus_tag="VUX16_001952"
     CDS             5670..6518
                     /locus_tag="VUX16_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET8124852.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(6611..7528)
                     /locus_tag="VUX16_001953"
     CDS             complement(6611..7528)
                     /locus_tag="VUX16_001953"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET8124853.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            7966..8171
                     /locus_tag="VUX16_001954"
                     /pseudo
     CDS             7966..8171
                     /locus_tag="VUX16_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(8482..8775)
                     /gene="rpmA"
                     /locus_tag="VUX16_001955"
     CDS             complement(8482..8775)
                     /gene="rpmA"
                     /locus_tag="VUX16_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET8124854.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(8792..9136)
                     /locus_tag="VUX16_001956"
     CDS             complement(8792..9136)
                     /locus_tag="VUX16_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET8124855.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(9152..9466)
                     /gene="rplU"
                     /locus_tag="VUX16_001957"
     CDS             complement(9152..9466)
                     /gene="rplU"
                     /locus_tag="VUX16_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET8124856.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(9502..9589)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(9648..10211)
                     /locus_tag="VUX16_001958"
     CDS             complement(9648..10211)
                     /locus_tag="VUX16_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET8124857.1"
                     /translation="MTFCAGYVNAYTFIVRGNTLVAGQAGNVVFLSVDLIQNNVSDVR
                     DKLLTLIAFIMGVFLLTIYKEKLRIVKKSILSLIPLAILSIIIAFVPQTVDNIYLVPP
                     LAFCMGLVTTAFGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILG
                     VPIMMSVFYLSMLFASWQKKVKEKASF"
     gene            10682..10981
                     /locus_tag="VUX16_001959"
     CDS             10682..10981
                     /locus_tag="VUX16_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET8124858.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         3551 a         2318 c         1869 g         3474 t
ORIGIN      
        1 aatagctaag gtaaaaattg tactcagtac tctcccaaga aattcgctct caaccttggt
       61 ttgtacttga gtaaaaaagt gaatattaaa aatcgtcata aacaattcac aaactaaatt
      121 tccagaaaag gaaagaaaag ttggaagtgg taatcccatc ataaaaactc cgacacctgt
      181 caaagccagt aaaatcaaaa gattataaac attagcttta attttactag ctagaagagc
      241 cccaatgatg gaaccaatag cccccatagt taaaatactt gcataggctc cttctgaccc
      301 gtaaagctga ttcgaaaagg gaagtagaaa ttcaaaagct gcaaaaaaga aattaacgct
      361 ggaagctacc agcaaaagga agaaaatttc ttgctgatgc cagatatagt gtaacccatc
      421 cttgatatct acaaaaatat ctctcccagt aaaagccttt ttctcttgaa cttttgcttc
      481 ctcttttgga aggaaagcca ctagaacaaa agcaatgaaa aaagtcagcg agtctagcag
      541 tagcgtcata tggagacttg caaactgtaa aacaaggaag gaaagaacag gagagctgac
      601 acctacaacc tgcaaaacca gctctaggcg agaattatag atcacaatct catctttctc
      661 caccacttca gttatgatag ctttattggc tgtgcgagaa aaggcaaaag caatagcctg
      721 cacaatgtta gcaacaatca aagcgccaat catccagcta tcattcctta tgaaagaaat
      781 agccagacaa agaatcccac aaacaagatc tgccgtcatt aaaatcttac gacgagaaaa
      841 acggtctgaa ataactccgc caaagggatt gacgagaata gatgtgacga gctcagaaat
      901 ctgatacatt cctaaaactg tctgtcctat agtccccata gaagccaacc agacactatt
      961 tccataatca tagagcatat ttcccatttt attgatagcc ccacggctaa tcaactgcac
     1021 tgcatagcga ttcatattaa agctcctctc aaattttgaa actattgtat caaaaccgaa
     1081 aggagctttt tattttttcc cttatttggg aaaattaact tttgacaaat ttttcgtagt
     1141 gttcctgata ataggctact tgctccggaa gacctaacac atcaaaaata tgcatggcct
     1201 cttgcatctg cttacagcct tctttacact gtcctttttg atataaggca aaacctttta
     1261 aataatggaa aacattacgc tcataaagct taataccttt gtcaataatc ttctctgtat
     1321 aagcctcaaa atagttggca ttataaaaag aagaatgctc taaacaatgc tggtaacaat
     1381 ttagggccaa aatcaaaact aatctcttat ggcgactaat ctcttggtaa aattcctccc
     1441 tctccataac ttctctacca atccgagtga catagtctac atcgtagaaa ctatagaggt
     1501 taccgaaaag aatcaactca tacatggtcc attcttctgt tttgaagaga taatctgcta
     1561 ccttatccaa atcatcctgc ttcatatcat aactcgcatc tctttgacaa atcagacctt
     1621 gtagcaaaat ccagttcagc tcaaaataaa ggggagtcgt cgaactctta gacttttcaa
     1681 gttgttctct ttgaagcttt tgaaaacctg caatatcgtt tgaatagtaa agtgggataa
     1741 tctgtgccat catagacaca tgttcatgat tataaaaatt ccttgcctta tccatgaaat
     1801 tttcgattgt tacatgaata ttatccaaaa tctcaaagaa acgggagact gccaggtcag
     1861 actccccaag ctcaaaacga gataactgag aggtagagca ggattcgcct gctgcttcct
     1921 ttaaagaata atttccactt gttcgaaatt cacgaaatac ttttccaaga tgttccattt
     1981 ttacacctgc tctgataatt cttcccactc aagcatagct tcttcctgac gatggctgat
     2041 tttgtccagc tcagcctgta attccatgag tttgtcggca tcgtttgttt ccaacatttg
     2101 ttcagaaatg gcttggcttt gactttctag ctcttcaatt tcagcttcta gactttcgat
     2161 ttgtcgcatg agtttgcgaa cttctttttg actttctttc tgggcctgat agtcattgac
     2221 tggacttgct tcctttgctt gattgctagt tgaagcttcc tcagtctgac tcatttctac
     2281 tgttgctttc ttttcaacat agtagtcgta atctccaagg tagagagttg aaccattctc
     2341 agacaattcc aaaacatgag ttgccacacg attgataaag taacgatcat gactgacaaa
     2401 aagcaaggta ccatcaaagt caatcaaggc attttctagc acttccttac tatcaatatc
     2461 caagtggttg gtcggctcat ccagaatcaa aaagttattg ttttccatag acaatttagc
     2521 taaaagcaaa cgagcttttt cgccaccaga tagcatgccg actgattttt taacatcatc
     2581 tcctgagaaa aggaaggctc caagacggtt gcggatttca acttctggtg tcagtttgaa
     2641 atcattccag agttcatcca gcaccgtatt acttggtgtc agcttgcttt gggtttggtc
     2701 atagtaacca acctcaacat tagcgccaaa gcgcttttct cccttgataa aaggaatctg
     2761 gtccacaata gacttgataa aggttgactt gccgatacca tttggaccaa cgatagcgac
     2821 agcattcatc ttacgaagat ctaggttgat aggttgtgac aagacttccc cgtcataacc
     2881 aatagcagta ttttcaacag tcaaaacaac attgcccgac gttttttcag actggaaggt
     2941 catgttggct gctttcttac cagcttcagg cttgtccaaa cgctccattt tttctagttg
     3001 tttacggcga gattgagcac gtttagtcgt tgaagcacga actagattgc gattgacaaa
     3061 gtcttccaga gcagcgattt ccttctgttg cttttcatag ttttttgcct cagtaactag
     3121 cttttgctcc ttcaattcga caaaacgaga gtaattcccc acatagcgat ccaaggaatg
     3181 cttggtcaaa tctagcgtaa ttgtcgcaac cttgtccaag aaataacggt cgtggctgac
     3241 gataatgagg gcaccgctat agtttaccaa gtaattctct agccaggcga tggtttcaat
     3301 atccaagtgg ttagttggct cgtccaagac caagagattg ggcttttcaa ggagcatttt
     3361 ggcaagtgcc aaacgagtat tttgaccacc agaaagctca gcaattttca tctgccacat
     3421 agactcgtca aacttgaatc cattcaaaat cgctcgaata tcagcttcat aggtaaagcc
     3481 acctgcttgg caaaaattct cagataagcg gtcataatct gacatcagtt tatccaaatc
     3541 ctcaccagac ttttcaccca tctccagctc catctgacgc agttgtctct ccgtccgacg
     3601 caaatcatta aagacatgaa gcatttcatc gtagatggta ttttcagact caaaacggct
     3661 atcttgggct aggtaagaca gagaaatatc ttttttctta ttgatttctc cgctagttgg
     3721 ctcttcttct ccaactaaaa tcttcaaaag agtagactta cctgcaccat ttttcccaac
     3781 aagagcaatc cgatctcgtt catcaacctg caggttgata ttatcgaaaa gaacctctcc
     3841 tgcaaaagaa cgttcaattt tattagcttg taaaataatc ataagagtag tatagcatgt
     3901 ttccctaagg cattcaagat aatcgtaagt cttttagtac aacttttata acataaaata
     3961 aactaaatta tgtatatttt atattagatt ccttcactat cttgttggat tttctaacca
     4021 gctaatcttg tttcaaatag ttatcgcaca agtctattat ttaattcttt tcatcattta
     4081 cgtacgtata gcagattgaa ataagatgag aacaaatcga ttgggaaagt aaaattaatt
     4141 tctataaatg ttttagcaat tgtttcgtac tattttagat tcagtctact atatacaata
     4201 ttttcggaac attcaacttt ttaactctat ttattactag atttcataat taaaaagcct
     4261 actgaccaag ctagaaagct tgatacaata ggctttttaa agactgatta tttaacagcg
     4321 tctttaagag ctttaccagc tttgaatgct ggtactttag aagctgcaat tgtcatttct
     4381 ttaccagttt gtggattgcg acctttacgt tctgcacgct cacgaacttc aaagttacca
     4441 aaaccgatca attgaacttt ttcaccagct gcaagatagt cagctactgc tgcaaataca
     4501 gcttcaactg ctgctgctga gtctttctta gtcaactctg tagcttctgc tactttagcg
     4561 atcaaatctt gtttgtttgc catgttaatg attcctccaa ataatttcta attaacaaat
     4621 ataatcatat cctaaaatcc cttttaggtc aagttaaaaa cgctatttct tcccatttta
     4681 tttatttttt taggagtggt aacgtatcaa aatagcccaa gcgttctcac ccgtgtgagt
     4741 ttgaataatg gaacccgttt ccaaaacaga aattggcttt tcaacataag cttgtaagct
     4801 ttctttcatc tcttttgccc aatcatcact accagaatat gaaattccaa tctctgctac
     4861 agcacgttca gaaagcgatg ttatcaactc atctaaccat tttttaaatg ttttagttcc
     4921 acgaccttta accattggct gcaattcatg gtttttcatt tgcatgacaa cacggatatt
     4981 gagaagagag ctcaacaagc cagttacacg gccaattcgt ccacctttga caagattttc
     5041 caaagttgaa acaccaatat aaagctctgt atggttttta acctcttcta catgagataa
     5101 aattgcctct atatctttac cttcttgagc taacttcgca gcctcaacaa cttggaattt
     5161 cagggcttgg tcagtgaagg aactatcaac aacagtcaca tctgcagtag ataggctagc
     5221 accttggcgt gctgcttcta ccgtacccga aagagcatgg gacatatgaa tagcaagaat
     5281 ttggccacca tctttgcata ggtcttcaaa aatctcagca aagacaccta caggtggctg
     5341 acttgttttc ggaagattct tactttcttg catcaactga agaaatttac cttcttcttt
     5401 caaatccgca tcagaataaa caacattatc aatcattaca gataatggaa caattgtaat
     5461 atctaattgc tttactagtt caggttcaat agtaacagat gaatcggtta caatcttaat
     5521 ttttgtcata gtatcaatct ttctatttta ggattcagat tggtttcctt acttctaatt
     5581 atatcaaaaa aaaattaaaa atcctaatgg agtcaatcaa attttccgta aaatttgata
     5641 taatcaactt ataagaaaag aggtgtccta tgattaaaaa aatttacccc atttttacca
     5701 ttttactagg tgctgctatt tatgcttttg gactgactta ttttgtagtt ccccatcatc
     5761 tctttgaagg aggggcgaca ggcattaccc tcatcacctt ttatcttttt aaaatccctg
     5821 tttccctcat gaacctgctg attaatattc cccttttcat cctagcttgg aagatctttg
     5881 gagccaaatc cctctattct agtttactag gaaccttagc tttgtccgcc tggttagctt
     5941 tttttgagca tattcccctt catattgatc ttcaaggtga tttactaatc acagccctta
     6001 tagcgggaat cctattggga attggccttg gaattatttt taatgctgga ggtacaactg
     6061 gcggaactga tattctagct cgtattctca acaaatacac tcatatatcc ataggaaaac
     6121 tgctctttat cttagatttt tgtattctca tgttgattct cctaatcttc aaggatttga
     6181 gattggtttc ctacacgctt ttgtttgatt ttattgtttc tcgtgttatt gatttgattg
     6241 gtgaaggagg atatgccggc aaaggcttta tgattatcac aaaacgtcct gaccaacttg
     6301 ctaaggcgat taatgatgac ctcggaagag gtgttacttt tatttctggt caaggctact
     6361 atagtaaaga aaatttgaaa atcatctact gtattgtcgg aagaaatgaa attgtgaaaa
     6421 cgaaggaaat gattcatcga atcgatcctc aagcctttat aactattaca gaagcccatg
     6481 aaatcctagg agaaggcttc acctttgaaa aagaataaaa agaggtaatg tcgtgacctc
     6541 aaaagttaga ctaaatcatc tatcttttgg gttacagaca acctcttttt tgttttattt
     6601 attcaagctc ttaagaccaa ttccgagtta cttcttcatc agcctttaac tgatccacta
     6661 attggtcaac tgagtcaaat ttggtcatat cacgaatgcg atcaagccaa taaaccatga
     6721 cggtttcccc ataaatatct tgattaaaat caaaaatatt gacttcaaaa cgtgcttctt
     6781 ctccatcaaa ggtcacattt ttcccgacac tagccatagc acgatacttc tgtctttgaa
     6841 tctcaacatc aacgacataa acgccatctg ctggcatata agtacggtct aaaagcacta
     6901 aattcgctgt cggataacca attgtacgac cacgagcatt accatgaact accatacctc
     6961 ttgatggaag cggtgccccc aaaagttttc ctgcttcttt cacatttcca tctaaaatag
     7021 cttgacggat acgagttgaa ctaatctttc ctttctcatc ttctacaggt ggaacaatga
     7081 taacttctcc atcaaagtaa tcctttaaat cttctgctgt ttttttgtca gaaccaaatg
     7141 tataatcaaa acctgcaaca ataattttgg cattcatagc cttgatataa gttgcaaaga
     7201 attcttgtgc agtgagacta gcgaattgac tactaaaatc aaggagatat aattcttcta
     7261 caccttcgcg ctttaatttt ctttcacgtt cagcagggtt caaaatatgc aaaaacaaat
     7321 ctggatgata aggctctaaa gcgatctttg gagattcatt aaaggtcata acgacgatag
     7381 gcaataaatc ctttctcgca gccttgttgg caacacgaaa taattcttga tgccccttat
     7441 gtatgccatc aaaatagccg agaacaacga ctgaatcaga tggtgtgcca atatcttttt
     7501 ggttttttat aggaatagta ataatcataa aataattata tcatagcgat agctatttct
     7561 ggaacagaaa atctgaaatg ttgttttttt cacatgaagt gtacctgttt tcaaaaggca
     7621 ctttattcta tcgttgctta actatgaact ttgcaatatt cttctcaaaa acttgtagga
     7681 catcttcaaa attttgcaag gagtgattag acttgttcgg taaccataaa gtgtcatact
     7741 atgcttatgt atgaaaaagc aatgcaacta actcctgaga actttaaatt actaattggt
     7801 gccgaaaagg tagaatttag aatcgaggta cacctatggc tgtaaaattt acaaaatgag
     7861 acaacttggg caagatgttt gaagaatttc ctaaactccc tgatttgaag caagtcactt
     7921 tccctgatga caaagaaaaa agccaaagca ataaagaaaa actagatgac tgctttccaa
     7981 caactcccat ctagtgtgct tcagactggg ctatttttct ctccatctgt tagcttggat
     8041 tctcagaccg tttcagctaa agaatatctt ttcccttatc agaaggaacg gctcaagcca
     8101 ttcagacaag tgaagggacg acaagccaat atttgaaacc agatagcagt tcttatagtc
     8161 aattgaaata aaatctgaag aaatcgagta ggaaactcat atcaatgttt aacagtgttc
     8221 tattccagat tcatactcaa tgaaaattaa agtgcaaact aggaagttag ccgcaggctg
     8281 tacttgagta cggcaaggtg aaactgacgt ggtttgaatt tgattttcga agagtatcaa
     8341 tccactatac atattaaaaa gtatgggtat caaaataaaa aaacaggctc tccgaaaact
     8401 cggaaagcct tattttaagc tgtttctagc ttcctcacct ttacatttca aggttcggga
     8461 taaaaggttc aatgaacctt tttattttgc gattgggtaa actgaaactt gttttttatc
     8521 gcgtccttta cgttcaaagc gtactacgcc ttcaacttta gcgaacaaag tatcgtctcc
     8581 accacgacca acgtttacac ctggatagat gtgtgtacca cgttgacggt aaaggattga
     8641 tccacctgtt acagtttgtc cgtcagctgc tttagctcca agacgttttg cttgtgaatc
     8701 acgtccattt gatgtagaac ctccaccttt tttgtgggcg aaaagttgca agttgttaag
     8761 agtcattttt aacataatgt tttcctccgt gttagttttc tgtgataact ctggtttgga
     8821 cgaactcaga agagttctcc gataagtttg ccatacctaa gaaaaatgat tcaaagaata
     8881 actgggtcat ttctctctgg tgtgaaggaa gatcttttgg tatttcaacc atcagatagc
     8941 caccttcatc ttcgtttaat tctaggattg gttcatagcc tgcaaatttc tcaatagaat
     9001 tgataaagtt aatggcaagc gtagaaaccg atgcacacac gacatctaag ccgtattcgc
     9061 cactctcggc gtgtccagta atttccgcac tcctcagctc gccatcttcg gctctctcaa
     9121 agactgcctg tatcatgtgt tctccttaaa attaagcgtt gattgcgttg atgacaactt
     9181 ttgtatatgg ttgacggtga ccttgtttac ggtggctacc ttttttaggt ttgtacttgt
     9241 aagtaaccac tttcttttgt tttccttgtt tttcaacagt tccaactaca gtagctccag
     9301 caacaagtgg agttccgaca acagtgtttt caccaccaac aagaacaact tcgttaaaag
     9361 taacttcttg accagcttca acgttcaatt tttcaacgta aactgcttga ccaacttcaa
     9421 ctttaacttg ttttccgcca gttttgataa ttgcgtatgt gctcattatg cacctcctat
     9481 gatttttatg ggtttccccg attttttgtg aagactcgcc tagcatcgtg ggacgaacca
     9541 cttaaacttg aataatcaag caacgatgtt cgtgcggttg cacaggatcg tgcatagtca
     9601 actcttcaag tatagcatat ctcctatttt cttacaagta ataacaccta aaatgaagct
     9661 ttttctttta cttttttctg ccaagaggca aaaagcatgc tgaggtaaaa aacgctcatc
     9721 ataataggaa caccaagaat ggtcttttca tgatagaaaa tcgtcaaata ggctgaaaag
     9781 acaacgccaa ggacaaaact actaagcagg ctaacaaata tgaatccttc acgcaaaaaa
     9841 ggagtgtgct tggttcggaa ataatctcca aaagcagttg tcaccagtcc catacagaag
     9901 gccaagggcg gcactagata gatattatcc acagtttgcg gcacaaaagc aataatgatt
     9961 gataagattg ccaagggaat caaggacaga atagattttt tcacaattct caatttttcc
    10021 ttataaatcg ttaataaaaa gactcccatt ataaacgcta ttaaggttaa aagcttatcc
    10081 ctaacatccg aaacattatt ttgtatgaga tctaccgaaa gaaagacaac atttccagct
    10141 tgtccagcta caagggtatt ccctcgaaca ataaaagtgt aagcattcac atatccagca
    10201 caaaacgtca aaaaagtgct aaccttttag actgacgtga tatttttctt ataggtaata
    10261 acctcatttt ccctcccatt gtattttctc ttagaaatat tgtaccattt tctttctaaa
    10321 aaatcgcagg ctaccattta gattttacta ttagcataaa aataataata gacaactatt
    10381 tatccaaaaa tagatagagg taacatgttt gcaaacaaag catacgaacc tttagtaaaa
    10441 tcatttccat gaaactagaa tagagcccct cttagcaaaa atcattattt taatttattt
    10501 ctaatcactc cttgacataa ataactctca ccaataaaag actatgtctt aaaaaaatgg
    10561 tataataaaa tcaatacttg ggcttgatga ctatgctact aataacaatt aggagagaaa
    10621 atcaggcact tgttaacaac aaggattatc cccttgagat gaaaggaact ttagaaatct
    10681 tatgatgaac atgcaaaaca tgatgcgtca agcacaaaaa cttcaaaaac aaatggaaca
    10741 aagccaagct gaacttgctg ctatgcaatt tgttggcaaa tctgctcaag atcttgtcca
    10801 agcgacctta actggcgata agaaagttgt cagcattgat ttcaatccag ctgtcgttga
    10861 cccagaagac ctcgaaaccc tttctgatat gaccgttcaa gccatcaact ctgctcttga
    10921 acaaatcgat gaaactacta agaaaaaact gggtgctttc gctgggaaat tgccattcta
    10981 aaaacaagga gctagaacaa tacttgtcga taacaaagac taagaaaggt gcaaaaatta
    11041 taggctctat aatatttgta gtgggtaaat tccctatgga tattatggag cctattttgt
    11101 gtagaaaaaa agtcccatat gacctataat gaaaagcgac aaaacaactc attagaaaga
    11161 atcatatgga acaattacat tttatcacaa aattactaga cattaaagac cc
//
LOCUS       DAVDZK010000056        10827 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVDZK010000056 DAVDZK010000000
VERSION     DAVDZK010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10827
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.057"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(71..1282)
                     /locus_tag="VUX16_001960"
     CDS             complement(71..1282)
                     /locus_tag="VUX16_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HET8124859.1"
                     /translation="MNNKTKKFTLATVLVLSLLGAGTLTSQSVVANDRLVSTQEINGQ
                     SYNILNSEVTSTSSGTTLVGIEGTFLTPDKQAILDRINAIRKEAADEGLVTSYVPIKW
                     STALEKTAFVRAAEASITIDHTRLSSKDIWTSWPAGNFSLSENLAWNYNGFMKAIQQW
                     YDEKADYVKSRSGVSVAGQTGHYKSLIDPKLTYMGLAAFENPVTQNGWITVAQSFGTA
                     SGGSEELAGSYGKAIQYTEANSSQIQTFATKANLFDKDLKAIRTHKTKNENTNSSQKN
                     EFNHSQYFGSWIQSNGRWWFKHNDGSYTSNGWEKINRTWYRFDNSGWMQTGWVKDGSW
                     YYLDGSGAMKTSWVKDNGSWYYLQDSGAMKTGWMKVSGKWYYAYSSGALAINTTTPDG
                     YRVNYNGEWVG"
     gene            1629..2581
                     /locus_tag="VUX16_001961"
                     /pseudo
     CDS             1629..2581
                     /locus_tag="VUX16_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2654..2938)
                     /locus_tag="VUX16_001962"
     CDS             complement(2654..2938)
                     /locus_tag="VUX16_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET8124860.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(2992..3927)
                     /locus_tag="VUX16_001963"
     CDS             complement(2992..3927)
                     /locus_tag="VUX16_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET8124861.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            4031..4474
                     /locus_tag="VUX16_001964"
     CDS             4031..4474
                     /locus_tag="VUX16_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET8124862.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLETDIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIECLEQFAEELAAKVG"
     gene            4590..4856
                     /locus_tag="VUX16_001965"
     CDS             4590..4856
                     /locus_tag="VUX16_001965"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET8124863.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            4853..5227
                     /gene="crcB"
                     /locus_tag="VUX16_001966"
     CDS             4853..5227
                     /gene="crcB"
                     /locus_tag="VUX16_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET8124864.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            5221..5550
                     /gene="crcB"
                     /locus_tag="VUX16_001967"
     CDS             5221..5550
                     /gene="crcB"
                     /locus_tag="VUX16_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET8124865.1"
                     /translation="MVIVYLAIACGFGALVRYLFSRYNQASKMPLGTLIANLLGCLLI
                     GLFYNHVESKEVYAILATGFCGSLTTFSTLNDELQRLLSDKKVFYSYLILTYLGGLVA
                     IFLGILL"
     gene            5669..6016
                     /gene="rplS"
                     /locus_tag="VUX16_001968"
     CDS             5669..6016
                     /gene="rplS"
                     /locus_tag="VUX16_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET8124866.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            6058..6129
                     /locus_tag="VUX16_001969"
     tRNA            6058..6129
                     /locus_tag="VUX16_001969"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6091..6093,aa:Arg,seq:cct)
     gene            6290..6463
                     /locus_tag="VUX16_001970"
     CDS             6290..6463
                     /locus_tag="VUX16_001970"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124867.1"
                     /translation="MKMSLIYSSAKKDFLYWNVLIFIMELPNDVKVQFYELRKKVQSF
                     NQLSKRFGMDVSG"
     gene            complement(6695..7549)
                     /locus_tag="VUX16_001971"
     CDS             complement(6695..7549)
                     /locus_tag="VUX16_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET8124868.1"
                     /translation="MENFGAVLKDIRISKNFRLKDLSCNEISESTISRFENGITKLSI
                     NHFYILLNRLGISFSEFEELVHCYYSKKECLFEELEHAVNSSDIFLLQELVDKIELKQ
                     KQEKSLCNYHIKLIAEQQINRLANLPYNSSKCNELIKYLLSVDTWMEYELKLFYNSVF
                     FMNTKTISLLYRIVIKKTRYFLKTNTGTHRIIPLYLFNLKLLLKNNLLDSAQFFIDDL
                     ENLLTRQGYYFEKNYLLFLKGIYLIKTNQIELGKKECSKAMRIFKEYNDSDTINELNQ
                     KFKLDLTI"
     gene            7643..8863
                     /locus_tag="VUX16_001972"
     CDS             7643..8863
                     /locus_tag="VUX16_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HET8124869.1"
                     /translation="MKKILLSTVALLSLVASLLANNPVSAQESSSQATYSKSSGSWIK
                     SGNRWWYKHSDGSYTTNGWEKINGTWYYFDSEGWMKTGWIKEYGKWYYLDDSGAMKTG
                     WCLVSGSWYYLNSSGVMQTGLQTINGKQYYLAAGGAMQTGWHNIGDDTYFFANSGENQ
                     NINRRALVLGETSTRAVPIADVNAMEKVFSNQNFSEVVRFPDRTKSEIIAKMQELFES
                     SSEGDVNYLYFTCHGGRDGRIYIGSDGLAFSGWELASVLKQYKGKFVVMLDCCHAGTI
                     ISKDNTGEGNEEASTEYFDLDEFVSGFSNMDGNEKSGEMIDSKFLVLCSSRGAEYSSG
                     GSLSLATKYWSLGSGWNPLQNSQAYLAADQNNNRRITLNELYTYSREQVLKQNSNQHI
                     EVYPDNSQFVLFKK"
     gene            8876..9994
                     /locus_tag="VUX16_001973"
     CDS             8876..9994
                     /locus_tag="VUX16_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET8124870.1"
                     /translation="MKVSKKITLFSLSFAGFVLLTLPQAGKAFELKEDWAFKGGIRYE
                     NGKVSKINNGYEVNIKVLDLPSTSAIEWTVRLNGEKQNTNFLAEERTVSKTEDKGRFL
                     HFYIPYGYRGDIVVEAKSGNEVKTWSTKVVDDVYSDSAKSGYFILDGEQILESSWDSV
                     NESYIATLPTVTSGKTVVAWREEGTLNLIKPGRIVRQYNSSGSYVELSPIFETASWLK
                     SNQNWYYQKQGQLVQNSWIKDQGSWYAFKSSGAMISADWLYDNGSWYYLKDSGSMVTG
                     WLKNGGSWYYLNKSGSMATGWIKDSGTWYYLKNSGSMATGWVKDSGSWYYLKNSGSMA
                     TGWVKDNGKWYYLASSGNMLRNTRTPDGYYVDGSGAWK"
     gene            10480..10749
                     /locus_tag="VUX16_001974"
                     /pseudo
     CDS             10480..10749
                     /locus_tag="VUX16_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002875.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
BASE COUNT         3443 a         1761 c         2145 g         3478 t
ORIGIN      
        1 atctctatac tatctgaaag tgaagattac tcactgtgag atagtataga gtctttttgt
       61 tgtagttaaa ttatcccacc cattccccat tgtaattgac acgataaccg tcaggtgtag
      121 ttgtattgat tgctagggca ccagagctat aggcatagta ccatttgcca gatactttca
      181 tccagcctgt tttcatagca cctgaatctt gaaggtagta ccagctacca ttatctttga
      241 cccaacttgt cttcatcgca cctgagccgt cgagatagta ccaactaccg tcttttaccc
      301 agcctgtttg catccaacca gagttgtcaa agcgatacca agttctattt attttttccc
      361 atccattact cgtgtatgag ccgtcattgt gtttaaacca ccaacgtccg tttgattgaa
      421 tccaacttcc gaagtattgg gaatgattga actcattttt ctgacttgaa tttgtatttt
      481 catttttagt tttatgagtt ctgatagcct ttaagtcttt gtcaaaaaga tttgccttag
      541 tcgcaaatgt ttgaatctga gaagaatttg cttctgtgta ttgaatggct tttccataac
      601 taccagctag ttcttcagag ccaccagatg ctgttccgaa actttgtgca acggtaatcc
      661 atccattttg agtgacaggg ttttcaaagg ctgcaagccc catataggtc agttttggat
      721 caattaagga tttatagtgt ccagtttgac ctgcaacact gacaccacta cgagatttaa
      781 cataatcggc tttttcatca taccattgct ggatggcctt cataaatcca ttgtagttcc
      841 aagccaaatt ttctgaaagg gagaaatttc ctgcaggcca ggaagtccaa atatccttgc
      901 tagacaagcg tgtgtgatca atggtgatcg aagcttctgc tgcacgaaca aaggcagttt
      961 tttctagtgc agttgaccat ttgatgggaa catagctagt aactagacct tcatctgccg
     1021 cctcttttcg aatggcattg atacggtcta agatagcctg tttatctggc gttaagaaag
     1081 ttccttcaat cccaactaga gtagtaccag aagaagtgct agtaacctca gagttcaaga
     1141 tattgtagga ttgaccattg atttcttgag tggaaaccag cctatcatta gcgactactg
     1201 attgtgatgt aagagttcca gctcctaaca aggaaagtac taaaactgta gcaagtgtga
     1261 actttttagt tttattgttc attttgtgtc ctcctatttt tattataaca tctttactgg
     1321 gtagagtaaa ctaaaattcg gtatagctag ggactatatt tattttaaat tgaaagttct
     1381 ataatgaagt tagccaccca ggcctcctaa aaattagatg ttttaactag cttatagcta
     1441 gtactcgatt tcatttgata agaggcttgg agctgttagg ctgacaagac aaggataaga
     1501 ttagccttgg tttagctgac aaaactgctt caagggttcc tcttgtcaaa tgaaagctct
     1561 tctaggcata agaaaacacc tctgtgttat acttgttgtt caaccacaaa cacaagaaag
     1621 gcacagagat gcaaaaccat tatactacaa aagccaaaca tttgacaatc gatagtcgtc
     1681 gcttaatcga acgatggaaa aaggaaggga aatcaaatag agaaatcgcc tctctgcttg
     1741 gaaaagctcc tcaaactatc catactgaaa tcaagcgtgg gacaatccga caatgtcttg
     1801 gaaaagggcg ctttaaagag gtttattctg ccgactatgc tcaacagtct tatgaaaata
     1861 atcgcaagcg ctcgatcaag aaatcaagat tgaacaagga gctgaaggaa aagattctcc
     1921 actatcataa ccaaaagttt tctcctgaaa tgatggtcaa ggctaagggc gttaacgtgg
     1981 gaatttttac catctactac tggatccatc atggaaaatt aggattgtca aaacaggatc
     2041 tgctctatcc tagaaaagga aaatctgtta agaaacaagc tagcaccaat tttaaccccc
     2101 ctggtcaatc caatctatcg aacagcgtcc tgaagctatc aatctgcgat tggagaatgg
     2161 gcattatgag attgatacgg ttctgcttac aagagtgaaa aattattgtt tactggtctt
     2221 aactgatcga aggactaggc atcaaattat ccgattgatt ccaaataaaa gtgctgaggc
     2281 ggtcaatcag gctttaaaac tcatcttaaa acaacaacaa attctttcca tcacggcaga
     2341 taatggtaca gaatttaacc gcttgtctga tgtattttct gaggaacata tctattatgc
     2401 gcacccctat gcctcttggg aaaggggaac taatgagaat cacaacaggc tcattcgtag
     2461 atggttacct aagggaacta agaaaacgac tcccaaagaa gtcgcattca tcgaaaattg
     2521 gattaataac tatcctaaaa aatgcttgaa ctacaaatca cccagagaag acttcttgat
     2581 ggctaacttg aacttgaaat ttggcgttga tttcaagaaa caaaaaagaa cagccgaaac
     2641 tgttctctta tcattatttg agaccgtatt ttttgttgaa acgatccacg cgtccatctg
     2701 cttgagtgaa cttttgacgt ccagtgtaga atgggtgtga gtctgatgaa atttccacac
     2761 ggatcaatgg gtaagtctcg ccttcgaact caactgtttc gttagagcgt tttgttgaac
     2821 cgctaaggaa ttggtaacca gtagttgtgt ccatgaagac aactgggcga tattctggat
     2881 ggatatcttt tttcattttg caatatttcc tttctgccat ggtctctttg cgagccatag
     2941 attgttacca tactagtcta tcagattctg aaaagtttgg caagtatttt atcagttttt
     3001 aagcaagttt tttaactttt ggtagatgat ttcgttttcc tctaggctat aggaattagc
     3061 accacttgct agagggtggc ctccaccatc atgttccttg gcaatttcat tgataggatg
     3121 gattttactg cgtaagcgaa cgcggtagtg gccatcagcc tgttccacaa aaattcccca
     3181 gagactaaca ctatcaatac gcccaggtgc acctacaatg gccgcagttt cagcatcggt
     3241 tacattgtat tgtttcaaga ttttctgact caggataacg cgagcagcac cattttcatc
     3301 cacttccaga tggtcgtaga tgtagccttg cagtttagca attttgtagc tcatagtgtc
     3361 cattttgcga gtgagagccg caaagtcaaa gttatgttct ctcaaataag cagccaggcg
     3421 aagagtccgt gcagtggtag aagggtagag gaagcgacct gtatcaccga caattcctgc
     3481 aaagagcaac tcagcatcgc gatctgccaa ggctagttgg gttgtttggg caaatagggt
     3541 aatcatctcg ctagcgctac ttgaactagt atcgacccaa gacaggtcac cgtatacatc
     3601 atcatttgga tggtggtcaa tcttaatgag aaaatcacct tgactatagc gcttatcatc
     3661 gatacgagca gtattagctg tatcacagac gatgacaagt gcgccttggt aggctctatc
     3721 ttcaacaaga tccatctcag ccatccaagt aagagttggt tcatcaaaac cgacggcttt
     3781 gatggttttt tctgggaaat gatgttccag caaggctttc aatcccacct gacttcccaa
     3841 ggcatcaggg tctggtttca tatgacgatg aatgataatg gtgtcgtatt ctttaatttt
     3901 ttctaaaatt tgttggcaaa tctccataaa taacctcaat tctttctcat ttcattgtag
     3961 cacaagaatt tttattttta aaatgaaaaa gatgtgatat aatggagaaa gataaattga
     4021 ggaggacgat atggcattag caaaaattgt atttgccagt atgaccggta ataccgaaga
     4081 aattgcagat attgtagcag acaaattacg tgacttgggc ttggatgttg atgttgatga
     4141 atgtacaact gttgacgctt cagacttctt ggaaacagac atcgctatcg ttgcgaccta
     4201 tacttatggt gatggtgaat tgccagatga gatgatggac ttctacgaag acctagcaga
     4261 tctcaacttg aatggcaaaa tctacggagt ggtcggctca ggagatacct tctacgatga
     4321 attctgtaag gctgttgatg actttgaccg tgtctttgtg tcaacaggag cagaaaaagg
     4381 ttcagagtgt gttaaagttg atctttctgc cgaggaagaa gatattgaat gcttggaaca
     4441 attcgcagaa gaattggctg ctaaagtagg ataagcataa aagtgcgctg atgtaatcaa
     4501 tcagtgcatt tttcttatcg agagttggga ttttactagc ctaatttatg gctttttgat
     4561 acaataattc aaataaagga ggagactgta tggatttaga tattattcgt caagaaatcg
     4621 atcaaatcga cgaccaaatt gtcaaactgt tagaagaacg aatgcattta gttgaggggg
     4681 tagttgctta taagaaagct tcgggtaaac cgattttaga tactaagaga gaagaagtta
     4741 tttttgaaaa ggttaggagt cgtgtagagg acaagcgcta tcaggagact attgtagcga
     4801 ctttttcgga catactcaaa cgttcgcgtg attatcagga tcagaatatc aaatgaaaaa
     4861 agaacaattt tatccgctag gaatttttct agctgctatg ttgggcggac ttgtccgata
     4921 tctagtttcc acctggttac cagccagtcc agactttcct tggggcactc tctttgtcaa
     4981 ctatctggga attttctgct tgatttatct tgtcaagggc tatctggtct ataaggggac
     5041 tagtaagggc ttgattttag cactggggac gggtttttgc ggaggtttaa caactttttc
     5101 cagcctaatg cttgatactg tgaagctgct tgatacaggg cgttatctta gtttagtcct
     5161 gtatttgctt ttgagcatcg gtggaggcct actcttagct tattttctag ggaggaagaa
     5221 atggtaatcg tctatcttgc aattgcttgt ggtttcggag ctttagtacg ctatttattt
     5281 tcccgctaca atcaagcttc taaaatgccc ttgggaacgc tcatagccaa tcttctaggt
     5341 tgtttgttga ttggattatt ctacaatcat gtagagtcta aggaggtcta tgctattcta
     5401 gcaacaggat tttgtggaag tttgacaact ttttcgactt tgaatgacga actccaaagg
     5461 ttgctaagcg ataagaaggt attttattct tacctgattt tgacctacct aggtggtttg
     5521 gttgcgattt ttttaggaat tctgctataa atttctttac ttttttttag aaatttggta
     5581 aactgtatct tgtgtgtaat ggacgcacaa aaatacagtt tatccgctga ggaagattcc
     5641 tcaagattga caaagatagg agaataaaat gaatccatta atccaaagct tgactgaagg
     5701 tcaacttcgt acagatatcc catcattccg tcctggtgac actgttcgtg tacacgcgaa
     5761 agttgtcgaa ggtaaccgtg aacgtatcca gatttttgaa ggtgttgtta tcgcacgtaa
     5821 aggtgctgga atctcagaaa actacacagt tcgtaaaatc tctaacggtg taggtgttga
     5881 gcgtatcttc ccaatccaca ctccacgtgt tgaaaaaatc gaagttgttc gttacggtaa
     5941 agtacgtcgt gcgaaattgt actacttgcg tgctcttcaa ggtaaagcag ctcgtatcaa
     6001 agaaatccgt cgttaattcg actaaaaaac tctgcttttc agcagagttt ttatctagct
     6061 cccttagttc aatggatata acaactccct cctaaggagt agttgcaggt tcgattcctg
     6121 cagggggcat ttttagtaat gtaaagaaag acaaagaaaa ttcaaaatgt ttatttgaag
     6181 gcaattttct caagttcatt tttaaaaata atttagcatt tttaattttt ttgaccaaat
     6241 tttgaccaaa aattatattt tggtcaatga ttatagaata aaatggatca tgaaaatgtc
     6301 tctgatttat agtagtgcta aaaaggactt cctttattgg aatgtcctta tttttattat
     6361 ggaattgcca aatgacgtta aggttcagtt ctatgaactt agaaagaaag tacaaagctt
     6421 taatcagctt tcaaaaagat ttggtatgga tgtttctggc taaggtatgt gacaaggtga
     6481 attgatcgtt attgaacaga gagcgttaaa aaagggaaga atcgttacta ttccactgaa
     6541 ttaaaacaag aaataaatca acaaaagcct atataataac aaatgtatta aaaataaaaa
     6601 gatttagttc agtgtaatgc agaaccaaat cttatggata aattatttgt ctaatttttt
     6661 aggaattata tctctaaaca atatcattta acaattaaat tgttagatct agcttaaatt
     6721 tctggtttaa ttcatttatt gtgtcactat cattatattc cttaaatatt ctcatagctt
     6781 tagaacattc ttttttacct aactctattt gattagtttt tataagataa atacctttta
     6841 ggaagagtaa ataattcttt tcaaaataat atccttgcct agtaagcaaa ttttctaaat
     6901 catctataaa aaattgagca ctatctaata aattattttt taataataat tttaggttaa
     6961 ataaatacag gggaattatt ctatgcgttc cagtattagt ttttaaaaaa tatcgtgttt
     7021 ttttgattac tattctatat agtaagctaa tggttttagt attcataaaa aacactgaat
     7081 tatagaaaag ttttagttca tactccatcc aagtatctac agaaagcaga tattttatta
     7141 attcattaca tttagatgaa ttataaggaa ggtttgcaag acgattaatc tgttgttcag
     7201 caatcaattt tatgtgataa ttgcataaac ttttttcttg cttttgtttt aactctattt
     7261 tatccactaa ttcttgaagt aaaaatatat ctgaagaatt tacagcatgt tctaattctt
     7321 caaaaagaca ttcttttttg gaataataac aatgaactaa ttcttcaaat tctgaaaatg
     7381 atattccaag acggtttaac agaatataaa aatgattaat agataatttt gtaatgccat
     7441 tttcgaaacg agaaatagtt gattcactaa tttcattaca tgataaatct ttaaggcgaa
     7501 aattttttga aatacgaata tcctttaaaa ctgctccgaa attttccata atgttcctct
     7561 tccatttctg caaaaaataa aacgcttgtt ttttatttat gatatgatta tacaaaaata
     7621 aaatagaaag gacaataata tcatgaaaaa aattttattg tcaacagttg ctttattaag
     7681 cttagtagca tctctgctag caaataatcc agtttctgct caagaatcat cctctcaagc
     7741 aacttatagt aagtcaagtg gaagttggat aaaatctggt aaccgttggt ggtataagca
     7801 ttctgatggt tcttatacta caaatggatg ggaaaaaata aatggtacct ggtactattt
     7861 tgatagtgaa ggttggatga agacaggttg gattaaagaa tatgggaaat ggtattacct
     7921 agatgatagt ggtgctatga aaactggatg gtgtttggtt tctggtagct ggtattattt
     7981 aaatagtagc ggtgtaatgc aaacgggact acagactatc aatggaaaac aatattattt
     8041 agctgccggc ggtgctatgc agacaggttg gcacaatatc ggagatgata cctatttctt
     8101 tgctaatagt ggggaaaatc aaaatatcaa tcgtcgtgct ttagttcttg gtgaaacatc
     8161 aacgagagca gtacctattg cagatgttaa tgctatggaa aaggttttta gtaaccaaaa
     8221 ctttagtgaa gttgttcgtt tcccagatag aacaaaatcc gagataattg caaaaatgca
     8281 agagcttttt gaatcttcta gcgaaggcga tgtgaactat ctttacttta cttgtcatgg
     8341 aggaagagat ggaagaatct atattggtag tgatggccta gcattttctg gttgggaatt
     8401 ggcgtccgtt ttgaaacaat acaaaggtaa gtttgttgtt atgctggatt gttgtcatgc
     8461 tggaacaatt atttctaaag ataatacagg tgaaggcaat gaagaagcct ctacggaata
     8521 ttttgattta gatgaatttg tatcaggatt ttctaatatg gatggtaacg aaaaatcagg
     8581 tgagatgatt gactctaaat ttttagtatt atgctcatca agaggtgcag aatactctag
     8641 tggtggatca ttaagtttag cgactaaata ttggtcttta ggttcaggat ggaatcctct
     8701 acagaattca caagcatatt tagcagcaga ccaaaataat aatcgcagaa tcacattaaa
     8761 tgaattgtat acatactctc gtgaacaagt tttgaaacaa aattctaacc agcatattga
     8821 agtttatcct gacaacagtc aatttgtgtt atttaagaaa taagggggca ataaaatgaa
     8881 agtatcaaaa aaaattacac tatttagttt gtcttttgca ggttttgttt tattgacttt
     8941 acctcaagca ggaaaggctt ttgaacttaa agaagactgg gcatttaaag gtggcattcg
     9001 atacgagaat gggaaagtca gcaaaattaa taatggatat gaagtaaata ttaaagtgtt
     9061 agatttacct agtactagcg caatcgaatg gacagttaga ttgaatggag aaaagcaaaa
     9121 tactaacttc ttagcggagg aaagaactgt atctaaaact gaagataagg gacgtttctt
     9181 gcacttttat atcccctatg gatatcgtgg ggatattgta gtagaggcta agagtggaaa
     9241 cgaagtgaag acttggtcta ctaaggtagt tgacgatgtt tattcagatt ctgctaagag
     9301 tggctacttt attctcgatg gggaacaaat cttagaaagt tcatgggatt ccgtaaatga
     9361 gtcttatatt gcaacgcttc caactgtaac atcaggaaaa actgttgttg cttggcgtga
     9421 agaaggaact cttaatttaa ttaaaccagg aagaattgtt cggcaatata atagcagtgg
     9481 atcatatgta gaactttctc caatctttga aactgctagt tggctaaaat caaaccaaaa
     9541 ctggtactat caaaaacaag gtcaattagt tcaaaattct tggatcaagg atcagggaag
     9601 ctggtatgcc tttaagtcat caggagccat gatttcagct gattggttgt atgataatgg
     9661 ttcttggtat tacctaaagg actcaggttc tatggtaaca ggatggctta aaaatggagg
     9721 ctcttggtat tacctaaaca agtcaggttc aatggctaca ggttggatta aagatagtgg
     9781 aacttggtat tatctaaaga attcaggctc tatggcgaca ggctgggtga aagatagtgg
     9841 ctcttggtat tatctaaaga actcaggttc aatggcaaca ggttgggtca aagataatgg
     9901 taagtggtac tatctcgcat catctggtaa tatgcttcgc aatacacgca caccagatgg
     9961 ctattatgta gatggcagtg gcgcttggaa ataaattttt aaaagagaaa atctactgag
    10021 aaggtagatt ttctttttag ttaatgaata tagaataaag tagatcagga ctggtctatt
    10081 ttattttgta actattaatg aatagtctta atgatgaagt tattttctga agatatttaa
    10141 ttgtgttgag atttgataaa actatagtgg attgaaataa gatataaaca aagagattat
    10201 ggaagtcaaa ttaatttcta aaaacgtttt aaaatcctta gcgtactatt ttagattcaa
    10261 tttaatatag tttaaaaata agaaaattac gtaccttatt cttggtgata aaaatgcgaa
    10321 tttagataaa tatatttgat ttgtagaagg tgctcataat ccatatttta aaatttatac
    10381 tattatactg aaatttaatt gtagtttatt gaatgctatg tatttttatt tcttaatgct
    10441 ataatataaa gtatatagag ttattttaga ggtgcagatt tggccaataa taggaaaact
    10501 gagacattag gtgtttcata tctttcaaca tttatagata agcatgagtt acttcaatct
    10561 tattttgaaa gtaatgataa aactccagta tgggatgggg aaattcatgt tcttaaatca
    10621 actagtgaga agaaggaaga aatattcggt aaagtgcctg ttcaaataaa agccactaga
    10681 caaaaaatga atgcacttaa atcattttca ttaaatatta gtgatttaga attatataaa
    10741 tcaaatggtg tactgacccc aaaaagttag acaaataatt tattcaaagg atttagttct
    10801 gtactgcaca ggactaagtc cttttag
//
LOCUS       DAVDZK010000057        10353 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVDZK010000057 DAVDZK010000000
VERSION     DAVDZK010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10353
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.058"
                     /strain="133b"
                     /db_xref="taxon:1313"
     misc_binding    complement(246..463)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(546..3242)
                     /gene="ppc"
                     /locus_tag="VUX16_001975"
     CDS             complement(546..3242)
                     /gene="ppc"
                     /locus_tag="VUX16_001975"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET8124871.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMNQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(3262..4491)
                     /locus_tag="VUX16_001976"
     CDS             complement(3262..4491)
                     /locus_tag="VUX16_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET8124872.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(4647..4873)
                     /locus_tag="VUX16_001977"
                     /pseudo
     CDS             complement(4647..4873)
                     /locus_tag="VUX16_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(5278..6174)
                     /locus_tag="VUX16_001978"
     CDS             complement(5278..6174)
                     /locus_tag="VUX16_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HET8124873.1"
                     /translation="MTKISFEIQQQIIQCFGLCFHYKDTVVSFMQTSGVLNDLILKWK
                     SEPKFVWAKNVINELNKTENGRSIIRRIATEFYKMKNISDEVQDRDRGLDALRKLKRL
                     IGDTQQNKVNETLNNSYHRSRQEMKIQLKQQLLQKIEELKTEYYSLFSSDNPQERGYR
                     LEKIVANLFRINDIDYHDSYRNRTNTQQLDGYFRFEGFDYLVEMKWEKNPVNSSKIAS
                     LKQKVDTKLTSTRGLFLSINGFRDEVIQDFSNKDAKILFMDGQELAYILENRISLYEA
                     LKVKIIGASKTGNPNVSIINQE"
     gene            complement(6225..9185)
                     /locus_tag="VUX16_001979"
                     /pseudo
     CDS             complement(6225..9185)
                     /locus_tag="VUX16_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569020.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            complement(9182..9991)
                     /locus_tag="VUX16_001980"
     CDS             complement(9182..9991)
                     /locus_tag="VUX16_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1837 domain-containing protein"
                     /protein_id="HET8124874.1"
                     /translation="MEKMHSYIKYLIHEDPIITDEGKQVEILHLDIQDDPEIFEDWAN
                     QFRRNYCSDDELAEMIGFMNISPKEYLKNFKLPSDSGIGLSTMSGDFGEILVSDYLQN
                     IEEYVVPRTRYDSRVNKDTSTQGSDVLGYKQDSSNVSNDEVVVIEVKSSASDSSSSQA
                     KNKLQEAINHSDKDFERFSTSIVASYLRLKKSNSDQENVVERFLNITDKPFNVIYGAV
                     AVYSNQSYDIDVIKTVVSKKHRDFQKLRLLVIHSDELMKFIRELYSKASEV"
     gene            complement(9975..>10353)
                     /locus_tag="VUX16_001981"
     CDS             complement(9975..>10353)
                     /locus_tag="VUX16_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET8124875.1"
                     /translation="KGYEVQLALIATKPELSYLSTLIRYEELYAINPNQARATPKEHH
                     DFIVNHLVDNTRQLEELAIFESIQIYQRDRSCVYDSKENTTSAATVLHDLLFGEWNTV
                     EKEMLKIGQERLWDMSKSNGKDA"
BASE COUNT         3274 a         2009 c         1505 g         3565 t
ORIGIN      
        1 taagttatat ctgcacctct ccttgaaaat ctactgaaaa cagtgtgaaa acgtcgtttt
       61 cagcagggct tctttagtgc accctttttt tgaaatagtt ttcaaacttt gagcgggggg
      121 tcgcttgaca ttttaccact agactttgta tttcctttaa catatttcac ttatctaaac
      181 aagcgacgcc atcgttttct ttccatacta atctccatca aaaaaaatcc tcacacaagt
      241 ttttgtgtga ggacgtcgat gcgcggtacc acctcaatta tagggaattt ccctatcgct
      301 cagtctcgca ataacgagat gcactgtaag gtgtgctcac cgaattttta taatttcaaa
      361 ttctaaatag cattcagccc aattttcatc atcgccactt atctgttttc agctaccaca
      421 gactctctaa aaagtttgta tgattacttt tctgaatggt taaattatat catttttaaa
      481 ctacttgtca atagtctatt agaatttttt tgatattcac ttttagcatt cactcttgaa
      541 aattatcaac ctgaattacg caatcctgtc gcaattccgt tgatggtgat atgaatcaat
      601 cgttcttgat cactggacaa ttctccacga cgttggcgtt taatcaactc taactgaata
      661 tagttgagaa tattaaagta aggcatacgg taatccaaac tagcttttag atatggattg
      721 tcagctaaga gttcgtcatg tccttcaata gccaagataa cgttcttagt aacttgccat
      781 tcatttaaaa tagtctcata gatggcctta acttgctcgt cttcacaaag tttagcatat
      841 tcaaaagcaa tattcatatt tgattttgac aaaaccatat caacatttga aagaagcgat
      901 tggaagaaag gccaattttg gtacatatct cgtaagatag caatattctc tggattttta
      961 ttgataaatt ccttgaagct tgaaccaacc ccgtaccatc cagggaacat aacacgactc
     1021 tgtgaccatg agaataccca agggatggca cgcaaaccac cgatttcagt aatagtctta
     1081 cgagcggctg gacgagaacc aatattaaaa cttgaaatag ccttgattgg acttgactcg
     1141 aagaaataat catagaaatg ctcattacca aagaccaaat cacggtagat atcgtaacta
     1201 cggtccacta cttgattcat aatagcttca taacgatttg gggtattggt atcgctcttc
     1261 ttctgagtaa tcatacggtt aatagctgcc gatactagca tttcaaggtt atagtaagcg
     1321 gcgtctttgt taccgtattt attcccaatt acttcaccct gctccgtcaa gcggatacga
     1381 tccttgatag acttgagcgg ttgagatgta atggcttcat aggttggccc accaccacga
     1441 ccgacagtac caccacgacc atggaagaag gtaaccttaa cgccaaattc atctccaata
     1501 gcagtcaatt gttgttgagc cttgtagaga gtccaacatg aagacaagta accgccatct
     1561 ttattactgt cagagtagcc aagcatgatt tcttggtagt tatttcgtga gtcaatccat
     1621 tttttggcaa ggctaagaga aagatatttt ctcattgttt cctctgaatg atccaagtct
     1681 tcaattgttt caaaaagggg aacaatctga acacgagccc tttccgtatc caccagtcct
     1741 acttctttta acagaatagc taattctagc atatcagaaa gactggttgc atgtgaaatg
     1801 atggtctgac ggatgacatc atctcccaac ttatctttca aaacacgagc cgtcttaaaa
     1861 atagctagtt cttttgctaa taattctgat ttttctgcgt gagtcgcaga aagaattcga
     1921 ggatcttctt ctaattcttt caagagaagg tcacactttt cttcttcgct caactcgcta
     1981 taacgagaat gaattcctgc tgatttcaag agttctgcca cacaggcttc atagacgcta
     2041 gagtcttgtc gcatatcaat tgatgctagg taaaaaccaa atatctctac tgcctgcaat
     2101 aattccacaa aatcacctga aatcaaggac tcgcccttat tttctagtag agaatctcga
     2161 atggcaatca aatccttgta gaaatcattg gcggtttcat aacgagtccc aacttcttca
     2221 tcctcaatca gataggtttt agttgcctga atttttgatt gaatatcaaa caaggcacga
     2281 cggtaaagct ctttttcgcg gtaaatcgag ttatccttgg attgacgagc catttctctg
     2341 acttgcttgc tgacgttgac aatgctagtt gaaagagaaa attcacgata aagttggtaa
     2401 atctttttat catagtagtt catgatgact tcacattgag tgagtgcaga ctgcttcaag
     2461 gtctctgctg taacaaatgg atttccatca cggtcaccac ctatccacat acccatggtg
     2521 attggtttag cttgttttaa attcagacca tgcgcttgcg ctaagcgctt atactccgtc
     2581 gtcaaatgag gtacagcttt caaaaaggag ctgttataat attccatagc attcgtgatt
     2641 tcgttagtca cttttaattt tttctcacga atcatgtctg tctgcatgat aatttcgatg
     2701 taacgacgca aatcattgta ccatttatct ttattgatca accccaactt aacatcacgg
     2761 tatttacgca aaagactatg aatatgattt gttaaatcca acatactttt gcgttgcact
     2821 tgtgttggat gggctgtcaa aacagggaca acattcaagt gttctaggat ctcaacggca
     2881 ttttcctttt ctgctaccaa tttaatcgtt gtagataatt tacctaaata gtcctgatca
     2941 atattatttt gatgattgat ttcataagct aaatccacat cctctgaaat attaatcaaa
     3001 agaggtaaga tagagaaata gcgtgaaata tagaccattt catcatttga taagctagtc
     3061 actagacggt ttagaccttg ataatcttcc tgcgttgata attctttcaa ctgtattatt
     3121 ttttcaaagg tctctggggc aagcatattt ttagtaatat cttccagtaa ttctgttaga
     3181 atcaagactt cttcttgcac aacactttta ttactataat tttctaattt ttgaagagac
     3241 ataaactatc ctttctttat cctacttcaa cagaaggttc attggttgat tttccaattc
     3301 tcggtacaac ttagcgcgtt tttcactggc atcaatattt aagacaaagg ctactgccac
     3361 tgataagact agaagactat ttccaccctg ggataagaag gggaaagtca ctcctgtaga
     3421 tggaatcaag cccgaaatcc ctccgatatt gacaaatacc tgaaccaaca tcatccctcc
     3481 gacaccgagc gcaaccatgg cattaaaagg attctctgct cggatgccga ccaagataat
     3541 ccgcaaaatc atgaaaaaca agagagctaa aataagactg gcaccaacaa agccaaattc
     3601 ttcaatcacg atagaaaaaa caaagtctgt atgagcttct ggcaaataac ctcgtttttc
     3661 aatcgagttc ccaagaccta gaccaaacca accgccattg accatggcaa aataagaatt
     3721 agctaactgg tgacccgcat cagcacgatc ggcaaaagga ttaaaaaagg cactaaagcg
     3781 cttggctaca tagccaaata ctggaatttt tgaaaaggtc tcaacaccga ttaggctgat
     3841 agtggtcaag acaaagacag aagcggcaga tacgagcgcc agaatggttg aaaaccagcg
     3901 ataagcgatt ccactaactg tatacataat caaggaaacc aagactaaaa tagtcgcatt
     3961 tcctaaatca gggaaaatgc ccaaacttcc aatcagaact aggagaacga atcgccaatc
     4021 attaaaagca cggggaagcc attgattttg agtcaaaact tgaaaatcat aagtagctat
     4081 ttcttcttgc tgtttggaga atcggtgagc taaataccaa ataataatga tttttaagta
     4141 ctcagctggc tgaatagtta ctcctgcaac cgaaatccaa ccgtatgccc cgtttacgga
     4201 aataccaata aaacgagcca agaacaataa aagcatttct attaatataa ctaaaatgat
     4261 tagtcgctca tttctcaaaa aatctagtct caatttataa attaaggcaa tcagtatcaa
     4321 actaacaatc caaaagattc cttggtttcg aaccaactgc aaggcgctct tgccttcttc
     4381 aattaaaata gcactagtgg tcgaatagac cacaatcaag cccaaaatag ataaaagcaa
     4441 gtagggaatc aagatggaat aatttaataa gtgcctctta ctaatcttca tagcatcacc
     4501 actctactag gatacagaca aatctgttcc aaattccgtt ttattttcta gttttgattg
     4561 ctattatacc attttttcag aaagaaaaaa actcttacct tacaatcctt cgaattttac
     4621 tgtttttaca gaattaaggc agaatttgaa atcgtaaaac cattttgaac aagagttact
     4681 tcaacccatt ggctccgact aattaagttg ctttcgtgaa tgctaaaatc agccgcaatt
     4741 tgttcataag tgcgctattc tcgcatgtat tgaatagtta ccataaggag atcgtctagg
     4801 cttaatttgg gttttcgtcc accttttgcg cgtttacgtt gcgttgataa gctgttttta
     4861 acacagctaa catctcgtgc gctgaacacc tacaaggctc ttgaaacggc tatcgcttaa
     4921 ttgtttactt gcttcatcat ccatagtttt attgtattgt attgtatttt tgtttcgcag
     4981 gaagtctatt attcctttcg ttccaaggtt tttacgcttt tagcaacact acacactcca
     5041 cgtgatgcgt ctgtggaact caaaaggttc ggggaacctt ttgaggatta attgcgtttc
     5101 tctaacaaac tcacacattc aacgtggcat gactgatgaa gtcatcataa aaatttcact
     5161 tgctgctctt ttacgttggc agcctgaacg gtcagaagta tcattgtata tcatttgtat
     5221 catggcatat aaagtatcgc tctattttat tgatggtttt aatatctctc ggaaaagtta
     5281 ttcttgatta attatagaaa catttggatt gccagtttta gaagcaccaa ttatcttaac
     5341 ttttaaagct tcgtacaaac taattctatt ttctagaata taagctaatt cttgtccatc
     5401 cataaataaa attttagcat ctttattaga aaaatcttgt attacttcat ctctaaaacc
     5461 atttattgaa agaaacagtc cccgagtcga agttagtttt gtatcaactt tttgttttaa
     5521 agaagctatt ttcgaagaat ttactggatt tttttcccat ttcatttcaa ctaaataatc
     5581 aaaaccttca aacctaaaat agccatctaa ctgttgagta tttgttctat ttctatacga
     5641 atcatggtaa tcaatatcat taattctgaa taaattagca acaatttttt ctaaacgata
     5701 tcctctttct tgaggattat cacttgaaaa tagcgaataa tactccgtct ttagttcttc
     5761 aattttttga aggagttgtt gcttgagttg tattttcatt tcctgtcttg aacgatgata
     5821 agaattatta agtgtttcgt taaccttatt ctgttgagta tcacctatca gtcgctttaa
     5881 ttttcttaac gcatctaatc ctctatctct atcttgaact tcatcagaaa tatttttcat
     5941 cttataaaat tcagttgcta ttcgtctaat tatcgatctt ccattttctg ttttattaag
     6001 ttcatttata acatttttcg cccaaacaaa cttcggttcc gatttccatt ttaatattaa
     6061 atcatttaga actcccgaag tttgcataaa tgaaacgaca gtatctttat agtgaaaaca
     6121 taatccaaaa cattgaataa tttgttgttg gatttcaaaa gatattttag tcattttttc
     6181 tcctttctat caacaatatt acatttcatt aattatctgt gtataataac ttggaccaca
     6241 attctatctg aaaaacctaa ttcatagata ttgatttctt tttccagagg tagcccatat
     6301 ttcagcctct ttattaacat agtcaatacg tccaattcct ctccaactag tttttcaaga
     6361 atattattaa tcgcatttaa aaccattgat gtttcatacc ctaatccatt atcacaaata
     6421 gagattatgt cagacatatc aattggtttt gacttacctc ttttctcaat actaattgat
     6481 ttttcagtac aactttccaa tatttgaaaa taagaaatcc ccttaatcca gagttgagaa
     6541 atataattta gattttctat acttagtttt ctcatctctt tgttatttga aaaatctatt
     6601 attttcttgg ttaaaacacc taataactct tcttccttct cacaagaaat gatagatgtt
     6661 ttattttcct gaacccattc ttttaataac tcagattgat ataatccaat tgagtttttt
     6721 gcaattattt cagtttctac tgaactggta attattttag attttatcaa gataaataat
     6781 tcttttattt tttctttttc ctcttcatta ttacctaaga aatatccaaa tgtattttca
     6841 gctaaactat cagtctccaa ttcagtagca tacatagaag caatataatt ttcaattgca
     6901 attagggtat tatcaatctg gtctatctta gaattaaaat ccttaaaata aagactgttc
     6961 tttcttttta attttgataa aatattattt atttttgttc tgtagtctac agaactgtca
     7021 aatctctctt taatcaaatt ccaaaaatca aattttatag gagcgaatcg ataatcagtt
     7081 ggaactactg atttaaactg tataatactg agaatattac tttgacaacc ctctgtatta
     7141 ataggattta acaatgcttt atagttttgt tttttccact tattttttgg tgatttataa
     7201 atattgggct ctgttaaaat tattgttcct tctgtatatt ttccagccct tcctgctcta
     7261 cctatcaaat tctgaaaatc acgaactttt attgcatctc ctgcttgata cacacttgag
     7321 ataatcaagt atttaatagg taagtttata ccttgtgcta aggttgaagt acatactaca
     7381 ttatttattt tactttttga aaaagcatac tctatagcaa tgcgtatccc cataggtata
     7441 cctgaatgat gtgaaaaaac tcctagctga ctacatgtat attcaacact atcatatcct
     7501 aaattttgac caattaaatt tcctattttt tcaacttcag acctatctga gttttttaag
     7561 aaatcagtta gatcataatt tctattattt aagtctataa atcttcgtaa aataacattg
     7621 accgtgtctt ttcttccaca aaaaattcct actccaccat tattaattag attaatccca
     7681 taataaatac ttatatcatt ttcgtttgtc agttctggaa aaactttttg tttgcgttct
     7741 tttccaagct gctctaattc actaacacta acagtacgtg gaacaaaaaa ttcttcttca
     7801 aatgtaatag gatctatgaa atataattgc tcattactcc cgtttaaatc actaaacgca
     7861 actcttttct ctgttgtttt aatcgaatta ttagaaacaa ttactccatc ttcgttaaac
     7921 caccgattta tagcttcact atttggtatt acagcagata ttaaaatctt ctgtattcct
     7981 tttgggaaaa tttgtttaac cgttgacaac agtaattcaa aatttgttcc acgacttgga
     8041 tcatcaaaaa gatgtgcttc atcaaatata caaagtccta tttcatcaat aaaactttga
     8101 tgatttctca ataaaaacaa caattttcct ggagtaagta taaaaactct ttttttacca
     8161 tcattaaaaa ttgagaaatc ctgtggaatc tccggtaaat caaaaacttc actaacaatc
     8221 acattattct catcaacgaa atgtgcatta atatcacgat atatttctct acataatgct
     8281 ctaaaaggtg caacaatcaa tgcattatca attctatttg aataaaatgc tgatcttaag
     8341 gttagattga ttgaggctgt tttacccgaa cttgttggca tctgaacgat tccagattta
     8401 cctgaaaaaa ttgcttgctt ccctaattcg atttgagatg gccaaagctc ctttatactt
     8461 cctgttgatt gtatataatc ctgccataaa gaaaaatcta atcctgaaaa ttcaggtaat
     8521 aatttcgttg atgaactatc tattttttta catacaactg ctaagagaca atttacaatg
     8581 attacagaaa aatcgcttcc attcctatat actttatctt gtaaatctct ataaatatct
     8641 atagaaaact cagtttttga taaaatataa tttctatatg attccaccag agtatttaac
     8701 tcactagagt atttaccttc tattggcgta tgattcaaaa agagtttatc tgtaataaca
     8761 ttaataaata cttttacaag agttatactc tcttctaata actgcatatc atccgatatg
     8821 tagttaacca taactctcga actaccatta taatcgccta gataataagc tgtggtacct
     8881 agtattgcaa tatagtcttg atattcagct gaatttccta atcctgacac cagcaatgca
     8941 tcaaaatatt cagcaacatt gtgtaattga ttttttaatt gtgaatcaaa actcttatga
     9001 ttgatataat cttcaaaata cttcctagca gtatctgcag caattgctaa tgccccaaga
     9061 aacgattttt gagcatcctc agaaattgga atatgacttt ctaaaggaat ttcaaattca
     9121 atcatctttg cctttgaacg cactaatttt gaaaaatata atgacttttt cccaaattct
     9181 atcatacctc actcgctttc gaataaagtt ctctaataaa tttcattaat tcatcagaat
     9241 gaatgaccaa tagtcgtaat ttctgaaaat ctctgtgttt ttttgaaact actgtcttga
     9301 taacatcaat atcatatgat tgattggagt agactgcaac agctccatag attacattaa
     9361 atggtttatc cgttatgttt aaaaatcttt ctactacatt ttcttgatca ctattagatt
     9421 tctttaacct taaatagcta gctacaattg aggttgaaaa tcgttcaaaa tctttatcag
     9481 aatgattaat agcttcttga agcttatttt tcgcttgaga gctactagaa tcagatgccg
     9541 atgattttac ttcaataact acaacctcat cattcgatac attcgaagaa tcttgcttat
     9601 atcctagaac atcacttcct tgagttgaag tatctttatt gactctacta tcataacgag
     9661 tcctaggaac cacatattct tcaatatttt gaagataatc agatactaat atttctccaa
     9721 aatcacctga catcgttgaa aggccaatac cactatccga gggtaattta aaatttttaa
     9781 gatactcttt aggggagata ttcataaaac ctatcatttc agcaagttca tcatcagaac
     9841 aataatttct tctgaattgg tttgcccaat cttcaaaaat ttctgggtca tcttgaatgt
     9901 ctaagtgaag aatctcaacc tgcttacctt catcagtaat aataggatct tcatgaatta
     9961 aatactttat ataactatgc atcttttcca ttacttttac tcatatccca caaccgttcc
    10021 tgccctatct tcaacatctc tttttcaacc gtgttccatt ctccaaatag taagtcatga
    10081 agaactgttg ctgctgaagt tgtattttct tttgaatcat atacacaact tctatctcgt
    10141 tgataaattt gaatgctttc aaagatagcc agttcttcca attgtcgtgt attatcaact
    10201 agatgattta caatgaaatc atgatgttct tttggagttg cgcgtgcttg atttggattg
    10261 atagcgtaca gttcttcgta tcggataaga gtgctcagat aggacagctc aggctttgtc
    10321 gcaatcaagg ctaattgtac ttcatatccc tta
//
LOCUS       DAVDZK010000058         9301 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVDZK010000058 DAVDZK010000000
VERSION     DAVDZK010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9301
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.059"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            147..884
                     /locus_tag="VUX16_001982"
     CDS             147..884
                     /locus_tag="VUX16_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET8124876.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRHDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEGR"
     gene            881..2572
                     /locus_tag="VUX16_001983"
     CDS             881..2572
                     /locus_tag="VUX16_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET8124877.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLAVVGTFYYRSSSSAIEATIEGD
                     SQTTISQTSHFIQSYIKKLETTSTSLTQQTDVLAYAENPSQDRVKGIQNLFLTILKAD
                     QDLKTVVLVTKSGQVISTDDTVQMKTSSDMMTEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTLDHQSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     MWTLLWASVTSLFAFLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAEETGAYELR
                     EVTRQFNAMLDQIDQLMADIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFQ
                     DSQRVVQVTKSLATYFRLALNQGKDLISLSDEINHVRQYLFIQKQRYGDKLDYEIAEN
                     PAFDHLVLPKLVLQPLVENALYHGIKEKEGQGHIRVSVQKEDTGLVIRIEDDGVGFQA
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSSPQKGTKVEIYINRIETS"
     gene            2688..3251
                     /locus_tag="VUX16_001984"
     CDS             2688..3251
                     /locus_tag="VUX16_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET8124878.1"
                     /translation="MNETQIQRETRQILEDVLEKANLKQGSIFVLGLSSSEVIGGQIG
                     KESSQEIGELIVETILGILGTRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVLPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPLLREIGHA
                     HVTALASRPKLIGGARAHYPQDSIRKS"
     gene            3273..9209
                     /locus_tag="VUX16_001985"
     CDS             3273..9209
                     /locus_tag="VUX16_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET8124879.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVDKEVI
                     SQEAKDLIQTGNPDGDEVVYGLVYQKAQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASAFLVGAMGLVVLPNAGAVDPVATLAPASREDVVEMEGYRYVGYLSGEILKRLGLD
                     TVLEEASVKSGEVTVVEVETPQSTTNQEQVRPENQAVETEEAPKEQAPRTEESPKEEP
                     KSEVNPTDETLPKVEEEKEVSAEPAPVEEVSGVVESKTDEQAPVKSESQPSDKPAEES
                     KVATPVEQPKIPEQPVQPRTPKESSQEENPTENRGAEETPKQEDEQPAVIETKDEAAN
                     QLVEEPKVETPAIEKQTGPAEEPKVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKAVE
                     KAPKQEESTPDAKVEETVEPKEETKTAKDTQEEGHVDEALAQEQLPEYKVTEGTLVEE
                     TTTELNYKTETTDDPTKYTDEETVLRTGEKGSQVTKTIYKTVEGVKTDQVLSTSTEVT
                     KEHVNQQVSRSTKPIEGTLVEESLEKIPFKEKIEEDDQLKKGSEVVAQEGKEGQKKIT
                     KTFNTIKGVKTEDAPKVIEEVIEVPQDKILKRGTKIFEKPVLTITAVESKDLKRTSDV
                     KYSLENPSKATIKSITLTLKKGDEIVKTLIVSPDNLTASLTDLQYYKDYKLETKMVYD
                     RGEGDEEEVLNEESLRIDLKKIEIKDIKSTKLIKVSENKEEIDDTNFTTIPTDKNNYY
                     LKITTNDNKTNRLAVKSITEETVDGENFYKITSEATDLIQHTKEEQIKNEYTYYIAKP
                     KQKENNVYYDFGELVEAIQNNPEGDYKIGESLNATNIKPNGKSYITKKFKGSLTSTDG
                     NKFAIHNLANPLFNEIENATIKDLIFSNVNINKPNTEQIATLGKDATNTIIENIKITG
                     SIVGSNDVAGVVNNLNNGSKMKNVAVIGKLHTEGKKGWSISGLVNNQRKANIERVYTD
                     VEITGERARGSALVSTLDRGTDPRDVRANGHIKKAVAKGSINLKNNVETGGVISKNWP
                     YGFMEDVISYVKVTNAEKLYGSGDIGDDDFGFPYLSRVVSVAGEATGNVTRKNANRLK
                     EISKEEADKKLEDFGITAKDFEAPTLLVDKLNNNISKDDEYKTTQDYDKTKEQAYRNI
                     AKLQPFYNKEWIVNQGNKLTNENLLNKKVISVIGMKDNDFVTDLSEVNKILVHYSDKT
                     KDIFTVVQKDSNVSQIKEYSINELKDIVYTPNMIAKDRDSIASKIKEKLNSVELQSDG
                     MYNLMDKRNNPQENTTERRKRYVRDLFLEESFEEVKNNLDNLVNKLLLNYDFQLNESK
                     ASEDVLLQKIEANKEKIMLGLAYLNRYYGINFDNMNIKEIMLFKPDFYGKNVNFLDFL
                     IKIGSSEKNVKGDRTLEAYRETIGGIIGINELNGFLHYNMNLLTEYTNINDWFKDATK
                     KNVYIVEPETSIEDFKNKKHRAYDGLNNDVHSRMILPLLNLKKAHIFLISTYNTMAYS
                     AFEKYGKNTEEARNEFKKEIDKVAKAQQDYLDFWGRLASDKVRNKLLKSQNVVPSPVW
                     DNMNAPGYGWLDKYGYKDGSSDYAPSRELFGPTGRYFPPNWNMGAMAKIWDNPYKEES
                     VYYMVTDMISDFGISAFTHETTHINDRLAYLGGWRHREGTFVEAFAQGMLQSPSVSNP
                     NGEYGALGINMAYERNNDGNQWYNYNPNKLKNRQEIDDYMKRYNEAMMLLDYVEAESV
                     LSKNLSDNSQWFKKVDRKMREKGSYNNNLVAPNQWDLVRDLNEDEKVIKLNTIKDLVD
                     NNFATRHGVGNGVFKPEDFTPNSAYVTVNMMAGIYGGNTSEGAVGALSFKHNTFRMWG
                     YFGYEKGFVGYASNKYKDIANKENNGLLSDKLIIQKVSEGRFNTLEEWKNSWYEEIYN
                     KATTKGFVPISVDNEQISTYARLKELFNEAVQKDLNELSNQTIKNKYRHTVALKEKVF
                     KQLLKESDGFSGDLFNTSQA"
BASE COUNT         3411 a         1465 c         1930 g         2495 t
ORIGIN      
        1 tacaacctca aagcggtatt ttgagaaacc tgtggctatc ttcctagttt actttttgat
       61 tttcattgag tataagaggt atttcctaag cagttagagg agaattttgc tatactgata
      121 ctagtaagtg acataaggag agaagcatga cctacacaat cttaatcgta gaagatgaat
      181 atctggtaag acaaggtttg actaaactgg tcaatgtagc agcctacgat atggaaatca
      241 tcggtcaggc tgaaaatgga aggcaggctt gggaattgat ccaaaagcag gtgccagata
      301 tcattttaac cgatatcaac atgcctcatc taaatggcat ccagttggcc agtctggtac
      361 gagaaaccta tcctcaggtt catttggtct ttttaacagg ttacgatgat tttgattatg
      421 ccttgtctgc tgtcaaacta ggtgtggacg actacctgct caaacccttt tctcgtcatg
      481 atattgagga aatgttgggg aaaatcaaac aaaaactaga caaggaagag aaagaagagc
      541 agttacaaga tttattgact aataggtttg aaggaaacat ggcccagaaa atccagtctc
      601 atctggctga tagccaattt agtttaaagt ctttagccag tgacttaggt tttagtccga
      661 cctatctgag ttccttgatt aagaaagagt tgggcttgcc ttttcaggat tatctggtga
      721 gagaacgtgt taaacaagct aagctcttgc ttttaactac agatctgaag atttatgaga
      781 ttgcagagaa ggttggtttt gaagatatga actattttac ccaacgtttt aagcagattg
      841 caggtgtgac acctcgtcag tttaagaagg gagaaggccg atgaagcgtt cttctctttt
      901 agttagaatg gttatttcca tctttctggt ctttctcatt ctcctagctg tggttgggac
      961 tttctactat cgatctagtt catcagccat tgaggctacc attgaaggcg atagccaaac
     1021 gactatcagt cagactagcc actttatcca gtcttatatc aaaaaattag aaacgacctc
     1081 gaccagtttg acccagcaga cggatgtcct agcctatgct gagaatccta gccaagacag
     1141 agtaaaggga atccaaaatc tgtttttgac catcttgaag gcggatcagg acttgaaaac
     1201 ggtggtactg gtaaccaagt caggtcaggt catttctaca gatgacactg tgcagatgaa
     1261 aacatcctca gatatgatga ctgaggattg gtaccaaaag gctattcatc agggagccat
     1321 gcccgttttg accccagcgc gtaagtcaga cagccaatgg gtcatttctg ttactcaaga
     1381 acttgttgat gcgaagggag ccaatctggg tgtgcttcgt ttggatattt cttatgaaac
     1441 tctggaagcc tatctcaatc aactccagtt ggggcagcag ggctttgcct tcattatcaa
     1501 tgaaaaccat gaatttgtct accatcctca acacacagtt tatagttcgt ctagcaaaat
     1561 ggaggctatg aaaccctaca tcgagacagg tcagggctat acactagacc accaatccta
     1621 cgtcagtcag gaaaagattg caggaactga ttggacggtg cttggcgtgt catcattgga
     1681 aaagttagat caggttcgga gtcaactcat gtggaccttg ctttgggcta gtgtcacatc
     1741 tctttttgcc tttctctgct tggtgtggtt cagtctcaaa cgctggattg ctcctttgaa
     1801 ggatctgaga gaaaccatgc tggaaattgc ctctggtgct caaaatcttc gcgccgaaga
     1861 aactggtgcc tatgaactga gagaagtgac tcgtcagttc aatgccatgc tggatcagat
     1921 tgatcaactg atggcagata ttcgtagcca ggaagaaacg acccgtcagt accaacttca
     1981 agccctatca agccagatta acccccattt cctctataac accttggata ccatcatctg
     2041 gatggctgaa tttcaggaca gtcagcgagt ggttcaggtg accaagtcct tggcaaccta
     2101 tttccgcttg gcgctcaatc aaggcaagga cttgatttcc ctgtctgacg aaatcaatca
     2161 tgtccgccag tatctcttta tccagaaaca acgctatgga gataagttag actatgaaat
     2221 tgctgaaaat cctgcctttg atcatctagt tttgcctaag ctggtgttgc aaccccttgt
     2281 agagaatgct ctttaccatg gcatcaagga aaaggaaggt cagggacata ttagggtctc
     2341 tgtccagaaa gaggatacag gcttggtcat ccgtattgag gatgatggcg ttggcttcca
     2401 agctgctggc gatagtagtc aaagtcaact caaacgtggg ggagttggtc ttcaaaatgt
     2461 cgaccaacgg ctcaaacttc attttggagc caattaccag atgaagattg attctagccc
     2521 ccaaaaaggg acgaaagtgg aaatatacat aaatagaata gaaactagct aactcccagt
     2581 caattctggg agttttatgc gtaattgggc aagctttcca ggttgtctat cttgctaaaa
     2641 acaagaaaaa acggtatgat agaagagtga taaaagaggt ggcagagatg aatgagacac
     2701 agattcaaag agaaacacgt cagatattag aagatgtttt agagaaggcc aatttgaaac
     2761 aaggctccat ctttgtttta ggcctttctt ctagtgaggt gataggtggt cagattggga
     2821 aagaatccag tcaagagatt ggcgagctga tagtggagac tatcttgggt attctaggta
     2881 ctagaggtat ccatttagct gttcaaggtt gtgaacatgt caatcgggcc ctcgttgttg
     2941 aacgtcaggt ggcagagcag tttggtctgg aaattgtcag tgtccttcct acacttcatg
     3001 caggaggttc ggggcagtta gcagccttca agttcatgca ggatccagtt gaggttgaat
     3061 ttatcaaggc tcatgctgga ttggatatcg gagacactgc aattggcatg catgtcaagc
     3121 atgttcaggt tccgattcgc cctcttttga gagagattgg tcatgcccac gtaacggcac
     3181 tggctagtcg tccaaaatta attggaggtg cgcgtgcgca ctatccgcaa gattctatta
     3241 gaaagtcgta agaatgaata aaggagatga aagtgtttaa aaaagatcgt ttttcaattc
     3301 gtaagattaa gggagttgta ggttctgtat ttcttggaag ccttttaatg gctccttctg
     3361 tagtggacgc agccacctat cactatgtag ataaagaggt tatttcacaa gaagctaaag
     3421 atttaatcca gacaggaaat cctgatggag atgaagttgt ctatggtttg gtgtatcaaa
     3481 aagctcagtt gcctcaaaca ggcacagaag catctgtttt gacagctttt ggtttgctga
     3541 ctgttgggag cttgctttta atctacaaga gaaagaaaat tgctagcgcc tttctagttg
     3601 gagctatggg attggtagtc cttcctaatg caggggctgt agacccagtt gcgaccctag
     3661 caccggctag tcgagaggat gttgttgaaa tggagggcta tcgctatgtg ggttatctat
     3721 caggtgaaat cctcaaaagg cttggtttgg acactgtttt agaagaagct tcagttaaat
     3781 ctggagaggt gactgtagtc gaagttgaga ctcctcaatc aacaacaaat caggagcaag
     3841 tgaggccaga aaaccaagca gtagagacag aggaagctcc aaaagaacaa gcacctagaa
     3901 cagaagaaag tccaaaagaa gaaccaaaat cggaggtaaa tcctactgac gaaacccttc
     3961 ctaaagtaga agaggaaaaa gaagtttcag cagaaccagc tccagttgaa gaagtaagtg
     4021 gagtagttga gtcaaaaaca gatgaacaag caccagtcaa atcggaaagt caaccatcag
     4081 acaaaccagc tgaggaatca aaagttgcaa ctccagtaga acaaccaaaa attccagaac
     4141 aacccgttca accaaggaca ccaaaagaat catcacaaga agaaaatcct acagaaaata
     4201 ggggagcgga agagacaccg aaacaagaag atgaacagcc agcagtaata gaaacaaaag
     4261 atgaggctgc taatcaactt gtcgaagaac caaaagttga aacgcctgct atagaaaaac
     4321 aaacgggacc agctgaggaa ccaaaagttg aacaagcagg tgaaccagtc gcgccaaggg
     4381 aagacgaaaa ggcaccagtc gagccagaaa agcaaccaga agctcctgaa gaagagaagg
     4441 ctgtagaaaa agccccaaaa caagaagaat caactccaga tgccaaggtt gaagaaactg
     4501 tagaaccaaa agaggagacc aaaacagcta aagatacgca agaagaaggt cacgtggatg
     4561 aggctcttgc tcaagaacaa ttacctgagt ataaagtgac tgaaggaaca cttgttgaag
     4621 aaacaactac agaacttaac tataaaactg aaacgactga tgatccaact aagtatacag
     4681 atgaagaaac tgtcctacga actggtgaaa aaggaagtca agttacaaaa acaatctata
     4741 aaacagtaga aggtgttaaa actgaccaag ttctttcaac cagtacggaa gtgaccaagg
     4801 agcatgtaaa tcaacaggta agccgtagta caaaaccaat tgaagggact cttgtagaag
     4861 aaagtcttga aaagattcca tttaaagaaa agattgaaga agatgatcaa ctgaaaaaag
     4921 gttcagaagt cgtagctcaa gaaggcaaag aaggtcagaa aaaaattact aagaccttta
     4981 ataccatcaa aggagttaaa acagaagacg ctccaaaagt tatagaggaa gtcattgagg
     5041 tccctcaaga caaaattttg aaacgtggta ccaaaatttt tgaaaaacca gtattgacta
     5101 taacggcggt tgagtctaag gatttgaagc gtacttcaga tgttaaatac agtctagaaa
     5161 atccaagcaa ggcgaccatt aaatccatca ccttaactct gaaaaaaggt gatgagattg
     5221 tgaaaacatt gattgtttca cctgacaact tgacagccag cctgacagat ttgcaatact
     5281 acaaggatta taaacttgaa acaaagatgg tttatgaccg tggtgagggt gatgaggaag
     5341 aagttctgaa tgaagaatct ttaagaattg accttaagaa aattgagatt aaagatatta
     5401 agtctacgaa actaataaaa gttagtgaaa ataaagaaga aatagatgat actaatttca
     5461 caacaattcc tacagataaa aataattatt atttaaaaat cacaacaaat gataataaga
     5521 caaatagatt agcagtaaaa tctattacag aagaaacagt agatggagaa aacttttata
     5581 agattacttc agaagcaact gatttaattc aacatactaa agaagaacaa atcaaaaatg
     5641 aatatactta ttatatagca aaaccaaaac aaaaagaaaa caatgtttac tatgattttg
     5701 gagaattagt tgaagctatt caaaacaatc cagaaggaga ttataaaatc ggagaaagtt
     5761 tgaacgctac taatattaaa ccaaatggaa aatcttatat tacaaagaaa ttcaaaggaa
     5821 gtttaacaag tactgatggg aataagtttg ctatacataa cttagctaat ccattattta
     5881 atgaaataga aaatgctaca ataaaagatt tgattttttc taatgtaaac ataaacaaac
     5941 caaacacaga acaaatagca acattaggaa aggatgcaac aaatacaata attgaaaaca
     6001 ttaaaattac tggaagtatt gtaggtagta atgatgtagc tggtgttgtt aataatttaa
     6061 ataacggtag caagatgaaa aatgttgctg ttataggaaa attacacaca gaagggaaaa
     6121 aaggttggag tatatctggt ttagttaata accagagaaa agcaaacatt gaaagagttt
     6181 atacagatgt agagattaca ggagaaagag ccagaggttc agctttagtt tcaacattag
     6241 acagaggtac ggatccaagg gatgtgcgag ctaatggaca tattaaaaaa gctgtagcaa
     6301 aaggatcaat aaacttaaaa aacaatgtgg aaacaggtgg agttatttct aaaaactggc
     6361 cttatggatt tatggaagat gtaattagtt atgtgaaagt aactaatgct gaaaaactgt
     6421 atggttcagg agacattgga gatgatgact ttggattccc ttatttaagt agagttgtta
     6481 gcgtagctgg agaagcaact ggtaatgtaa caagaaaaaa tgcgaataga cttaaagaga
     6541 tttctaaaga agaagctgat aaaaaattag aagattttgg tattactgcc aaagattttg
     6601 aggctccaac attattagta gataagttga ataataacat atcaaaagat gatgaatata
     6661 aaacaacaca agattatgac aaaacaaaag aacaagcata tagaaatatt gctaaattac
     6721 aaccttttta taataaagaa tggatagtta atcaaggaaa taaattaact aatgagaact
     6781 tattaaataa aaaagttata tctgttattg gaatgaaaga taatgacttt gttacagatt
     6841 tatccgaagt aaacaaaata ttagtacatt attcagacaa aacaaaagat atttttacag
     6901 ttgtacaaaa agattcaaat gttagccaaa ttaaggaata tagtattaac gaattgaaag
     6961 acattgttta tacacctaac atgatagcaa aagatagaga ttctatagca agtaaaatta
     7021 aagaaaaatt aaattctgtt gaattacaat ctgatggaat gtataattta atggataaac
     7081 gtaataatcc tcaagaaaat acaacagaaa gacgaaaaag atatgtaaga gatttattct
     7141 tagaagaaag ttttgaagaa gtgaaaaata atttagataa cttagtaaac aaattgttat
     7201 taaattatga ttttcaatta aatgaaagta aagcttcaga agatgtttta cttcaaaaaa
     7261 tagaagccaa taaagaaaaa ataatgctag gattagctta tttaaatcgc tattatggaa
     7321 ttaattttga taatatgaat attaaagaaa ttatgttgtt taaacctgac ttttacggaa
     7381 aaaatgttaa cttcttagat ttcttaatta aaataggttc aagtgaaaaa aatgttaaag
     7441 gagatagaac tttagaagct tatcgtgaaa ctataggtgg aataattgga ataaatgaat
     7501 taaatggatt tttacattat aatatgaatt tattaactga atatacaaat ataaacgatt
     7561 ggtttaaaga cgcaactaag aaaaatgttt atattgttga accagaaact tcaattgaag
     7621 atttcaagaa taaaaaacat agagcatatg atggtctaaa caatgatgtt catagcagaa
     7681 tgattttacc tttattaaat cttaaaaaag cacatatatt cttaatttca acatataata
     7741 caatggcata tagtgctttt gaaaaatatg gtaaaaacac agaagaagct agaaatgaat
     7801 tcaaaaaaga aattgataaa gttgctaaag cacaacaaga ttacttagat ttctggggta
     7861 gactagcttc cgacaaagta agaaataaat tactaaaaag tcaaaatgta gttccttcac
     7921 ctgtctggga taatatgaac gcacctggtt atggttggct agataaatat ggatataaag
     7981 atggttcttc tgattatgct ccttcaagag aattatttgg tcctactgga agatatttcc
     8041 caccaaactg gaatatggga gcaatggcta aaatctggga taatccatac aaagaagaat
     8101 ctgtttacta tatggttaca gatatgatta gtgattttgg tatctctgct ttcacacacg
     8161 aaacaactca tattaatgat agattagctt atcttggagg atggcgacac agagagggaa
     8221 cttttgtgga agcttttgct caagggatgt tgcaatctcc atctgtttct aatcctaatg
     8281 gtgaatatgg agcccttggt atcaacatgg cttatgaaag aaataatgat gggaaccaat
     8341 ggtataatta caatccaaat aaattaaaaa atagacaaga aattgatgat tatatgaaac
     8401 gatataatga agcaatgatg ttactagact atgttgaagc tgaatctgtt ttaagtaaaa
     8461 acttatctga taacagtcaa tggtttaaga aagttgacag aaaaatgcgt gaaaaaggaa
     8521 gttataacaa taatttagtt gctccaaacc aatgggattt agttcgcgac cttaatgagg
     8581 acgagaaagt aattaaatta aatactataa aagatttagt agataataac tttgctacta
     8641 gacatggtgt tggaaacggt gtgtttaaac cagaggactt cactccaaac tctgcttatg
     8701 taacagtaaa tatgatggca ggtatttacg gaggaaacac aagtgaaggt gctgttggtg
     8761 cattgtcgtt taaacacaac acatttagaa tgtggggata ttttggatat gaaaaaggtt
     8821 ttgttggata tgcttcaaat aaatacaaag atattgctaa taaagaaaac aacggcttac
     8881 taagtgataa gttaatcatc caaaaagttt cagaaggtag attcaacact cttgaagaat
     8941 ggaaaaattc ttggtacgaa gaaatatata ataaagctac aactaaagga tttgttccta
     9001 tatctgttga taatgaacaa atttcaactt atgctagatt aaaagaatta tttaatgaag
     9061 cagtacaaaa agatttaaat gaattgtcta atcaaacaat taaaaataaa tatagacata
     9121 ctgttgcatt aaaagaaaaa gtctttaaac aattactaaa agaatcagac ggtttctctg
     9181 gtgatctatt taatacatca caagcataag atgaataaaa tcggctcttt gtcaactgta
     9241 gtgggttgaa gaaaagctaa gctcgagaaa ggacaaattt cgtcctttct tttttgatat
     9301 t
//
LOCUS       DAVDZK010000059         9091 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVDZK010000059 DAVDZK010000000
VERSION     DAVDZK010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9091
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.060"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(61..432)
                     /locus_tag="VUX16_001986"
     CDS             complement(61..432)
                     /locus_tag="VUX16_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET8124880.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQLA"
     gene            complement(491..1924)
                     /gene="glgA"
                     /locus_tag="VUX16_001987"
     CDS             complement(491..1924)
                     /gene="glgA"
                     /locus_tag="VUX16_001987"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET8124881.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(1921..2727)
                     /gene="glgD"
                     /locus_tag="VUX16_001988"
     CDS             complement(1921..2727)
                     /gene="glgD"
                     /locus_tag="VUX16_001988"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: protein motif:HMM:TIGR02092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET8124882.1"
                     /translation="MKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLA
                     KKDISEVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKK
                     EHPEKLRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQ
                     KIYTKVKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLF
                     PRVVIGEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(2672..4060)
                     /locus_tag="VUX16_001989"
     CDS             complement(2672..4060)
                     /locus_tag="VUX16_001989"
                     /inference="COORDINATES: protein motif:HMM:NF012398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET8124883.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPTMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     SLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHIDNKTQRGPDNFPFLFETFWL
                     KPNGCPQLRCSY"
     gene            complement(4604..6883)
                     /gene="pulA"
                     /locus_tag="VUX16_001990"
     CDS             complement(4604..6883)
                     /gene="pulA"
                     /locus_tag="VUX16_001990"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET8124884.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AVNDAPVWKTFEMKRGNSYSHNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQIIRLKTKTDAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKERLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(6995..8953)
                     /gene="ligA"
                     /locus_tag="VUX16_001991"
     CDS             complement(6995..8953)
                     /gene="ligA"
                     /locus_tag="VUX16_001991"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET8124885.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRKLVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMESLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTIVADAALSGLTVVLTGKLKRLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
BASE COUNT         2691 a         2021 c         1659 g         2720 t
ORIGIN      
        1 ttgacctggg gacttataat ttgtccaact aattttcctg ttaaaagacc ttctttgact
       61 tcaagctagt tggcagtgaa ataggcaata ccaagggatt ttgctaatct ctccaactat
      121 tggtgtaaat ccaccagaca ccagaccaac taggatgcca ttcttttgga gaatagagat
      181 gaactctggg acatttagcg atagatgaat tgagttgaag acgttatcaa agaccaaaat
      241 aggaagacct tccaacaagg acactctttt tcttaaactg ctttcaaaga ccaactctcc
      301 tcgcattgcc cgacttgtaa tctgcgaaat ttccgcctca tgacctgcct ctctccctaa
      361 aagatcaatc acttcttcta ggattaaggt tccatctaca tccaaaacac acaagccttt
      421 tacttgagac atcagttctc ctctctaaac agcctaaaaa tcgtatgaag tcatcatacg
      481 attttatcta ttaattaact aaactatggt acaagtcaag gtatgacttg caggctgtat
      541 cccatgagaa gtcactctcc atagcttgtt tttgtaggtt tctccaaatg tctggatggt
      601 ttctatacaa gtccaatgct gtttggaaag tccaatttaa ccaataagga gatagattgt
      661 caaagctaaa gccagtaccg cttccttcga ttggattgaa agcgcgaact gtatctcgca
      721 agcctccaac ttcatggacc aatggcaagg ttccataacg catagccatc atttgagaca
      781 agccacacgg ttcaaaacga cttggcatga ggaagaggtc acaagcagcg tagatttcct
      841 gagcaagttt gacatcaaaa gtgatatttg ttgatagctt gtctgggtaa atctgagcaa
      901 accatgagaa agctccttca aaggctggat cgccagttcc caaaagaaca atctgaacat
      961 cttcttgcaa gatatggtga agactttcga ccaccacatc aaaacctttt tgacgtgtca
     1021 aacgagaaac aattcccacc agtggaacgt ctgctctaac aggcaagcca actctttctt
     1081 gcaattttgc cttatttttg gctttcccag acaaatcttc ctgattgaaa tgatagtcta
     1141 aaagagcatc cgtctgagga ttataaagat cagcatcaat cccattcacg ataccagata
     1201 ctttaccaga ctccatttta agaatctgat ccaaattaca tccaaactga ctagtcataa
     1261 tttcatgagc atagctaggt gaaacagttg aaacacggtt cgcatagaga atacctgcct
     1321 tcatccagtt cagacagttg ttccatcgaa gggtgccatc agcgtaacgt tcaaagccaa
     1381 ctccaaacaa atcacccaac attccttctg aaaattgtcc ttggaattct aaattatgaa
     1441 tggttaaaac tgtttcaatg tcctcatagg cttgaatcca acggtatttt tccttcaaca
     1501 agaaaggaat catagctgta tggtagtcat gaacatggag aagatcagga ataaagtcaa
     1561 tcctttccat agcctcaatg gcagccagtt ggaaaaaggc aaagcgttct ccgtcatcaa
     1621 aatcaccgta aacatgacca cggaagaaat aatattgatt gtcaataaag tagaaggtta
     1681 caccatttaa tactgttttc ttaattccac aatactgtct gcgccaacca acgctcacct
     1741 caaaatgaag cacatcttca atctgacttc caaatttagc ctctaccata tcatagtagg
     1801 gtaaaatcac tgcaacttcg tgcccagctt ttaccagtga ttttggaaga gcgccaatga
     1861 cgtctcccaa accacctgtt tttgaaaagg gtgcaccctc tgctgctaca aataaaattt
     1921 tcatgaatga atatcctctg ttactttagc acctttctta accacaactg gatgttctgc
     1981 agttcctcga atcacaacac caggctcaac ttcaacccct ttgtccaaga tagcatattc
     2041 gacctgagcc ccttctccaa taacaacacg agggaagagc aggctatctt taaccaagct
     2101 atccttatgg acatgaatat tacgtgatag aacagaatta gctacttgac cttcaataat
     2161 actaccagag gcaaactgag aagtgcttac cttagatgta ttagcatagt aagttggctc
     2221 ttcgtttttg acctttgtat aaatcttttg gtttggtgag aaaagagaat agaatttttg
     2281 tgattcaagc atatcgatat tcgcttgata ataagattta acagagtgaa tattggctag
     2341 atagcccgtg tactcgtagg cgaaagctcc ctcttttaca gccaaatccc gtaaaacata
     2401 gcgcaatttc tctggatgtt cttttttagc ttcttcttcc aagtgttcaa tcaaccaagg
     2461 tgtatcaacg acaaagatat ctgtagacat attgaacgtt tcagctgttg acttgctatc
     2521 aaagagttta tgagaaagaa catggtctgt ttcatctaca tccaagattg catttacttc
     2581 tgaaatatct ttcttagcta gttttttata aactacagtg ataggctctt ttgttgtact
     2641 atgtaggtgg aaaacttggt tcaaatcaat gttaataaga acatcgcagt tgagggcaac
     2701 cgtttggttt gagccagaac gtttcaaaaa ggaatgggaa attatctgga ccacgctggg
     2761 ttttattatc aatgtggact gtacctactt caagtttttc agcaatttca aaggcttttt
     2821 tgaaatcatt tgtaaagact gatgattgaa ggccgaattc agattcgttg gcaaaggcaa
     2881 tagcttcctc tacactagcc acacgaatga ttggtaaaac aggaccaaat ggctcttccc
     2941 atgccacttt catatctttt gtaacttggt caaaaagcac tggccagaga agattgccct
     3001 cacgtttgat tggtgtaaga gcctgagcct ctttttcttg tgcatcctca atcaagctcc
     3061 aaatgaagtc ggctgaagca ttgtcaataa caggtgtaat atcagcattg tcaaatggat
     3121 caccaactgt taatttagaa acttcttcct gaagcaaagt agctaattta tctgctacac
     3181 tttcgagaac aatgacacgt ttaatggccg tgcaacgttg tcctgagtag ctaaaggctc
     3241 ccgcaacaat ttgcttggca gcatgttcca aatctgcatc ttctagtaca agagctgcat
     3301 ctttcccacc aagttccaac atggtaggac gcataccagc taaacgacca atacgttctc
     3361 caataggagt tgaacctgta aagttgatga agttgacttc tttgtgctca atgatataat
     3421 ccccaatttc tgaaccacga cctgtaatgg tgttgaaaac acctgccgga atccctgctt
     3481 cttcaaatgc tttagccaac aagagtccag aaatggaacc ttgtgttggt ggcttaaaca
     3541 tgaccacatt ccctgcaatc aaggcaggtg caattttaga agcagataaa ttaactggat
     3601 aattaaaggg agcaatcgct agcacgatac caactggttc acgacggaca acagccagtt
     3661 tgtttttact tgctgcctca aaaccaccac cttccattgc ttgtccagtg atacggagac
     3721 cttcctcagc agcataacga atcaagtctg ctgtacgcac tacttctcca attgctgctt
     3781 taatcccttt tgctacttct ttggcaagga tagtaccaat ttcttcctta tcgcgttcta
     3841 aaatagctgc tgttttatgt aaataagccg cacgttcaac tgctgataaa gctcgccatg
     3901 ctggcagggc tgcacgcgca gcttgcatag cctcatcagc ttcagtctga gtcatggctg
     3961 gaactgtacc caattcttct tgattgattg gtgaataaat cgtaatttct tgttcagatg
     4021 atttccattt tccatttact aaattctgat atcttgtcaa attctcatcc tcctgaaaat
     4081 gattaagata tattttacca aattttcaga aaatcacaac cctttttgca aaatttttga
     4141 gattattttc acaagcttga tttttcaaag tatactcaat aaaaataaaa aaaatccact
     4201 acgtcaaggc aaggctaatg tggtttgaag aaattttcga agagcgtgaa tgagtatcat
     4261 ctatagtaaa ataaaaaact gaacaatttg gttggggaca accaaaccaa tttctcacaa
     4321 tgttttagaa acaagggtgt gctattccaa tttcagccta ctataactgt catagattgc
     4381 tgaaacaaag tctagataaa agtcttcata ataacaagac cccctatcca gtgttcaaaa
     4441 actttgatag gaggtcttgt tttgtgaaaa tatttatcaa attttctata caagtgagct
     4501 gttagccaga ttctttctat tctttcaatt tcaataaatg gattttttac caatactcat
     4561 aactgggaat ttgtctgtgt aaaaatagcg agatagatgg tatttataaa acactcaaga
     4621 cagctagact aatatcattt aaaacattat cttcttttga gcgactgttg gttaccaaca
     4681 tagctaaatt tcctgcattt tcaaattgat agggttctga tttagcattc acaaccacca
     4741 agaggcgttc tttgccgtga acttcataga taaggcagcc gctatgttca atcgcagaat
     4801 gcacaaagac atgatggtaa atttcatcat agctagagta agaaaaggca tcagtttttg
     4861 tcttcaatcg gatgatttga cggataaact caatactgtc ttgacgctca ttaatcaagt
     4921 tccagttcac ttggttcaca ctgtcaggag cattatagct attcatcgca cgctctctat
     4981 catcatgggt caactcacca ttttcaccag tcgcaaccag tttggtacga ccaaattctt
     5041 gaccgatttc cataaaggcc atcccctgca tgagcagatt catggctgtg gcagtttcga
     5101 ccttgcgcat gatttgctct gaactttggt ctggatgaag ggttgccaat aaatcgtgaa
     5161 gattgtaatt gtcatgggct tctacatagt taagcacctg atttggatgt gtatagcttc
     5221 ctaattcacg acttcctagg attgctttag ctagaattgg ctctgtcgca gcaccactga
     5281 caaaacctga cttgatagca ccataaactt ctcccccttt gacagcatcg cgctgattgt
     5341 cattaaagaa accaatattt ggcatctggt aggcattgtc cttcttggcc ttatcataag
     5401 gggcaagacc tgttcccatg tcccatcctt ctccatagag gataatgttg gagtcgattt
     5461 catccaagct ttgacgaatc atctgcatgg tcttgacatc atgaatcccc atcaagtcaa
     5521 aacggaagcc gtcaatatta tattcctgca cccagtatag aagagaatca atcatatact
     5581 tgcgaaacat ttcgtgttca ctggctgttt catttccaac acccgttcca ttctggaagg
     5641 taccatctgg attcatacga taatagtaat cagggactgt tgtttggaat ggtgcatcaa
     5701 caactgagaa ggtatggtta tagactacat ccataatgac tccaataccc gcatcgtgat
     5761 aagcttgaac catcaccttc aaatcacgaa tgacctgagc tggatcatct ggattagttg
     5821 aaaaactagt ttctggcgcg ttatagtttt gtggatcata accccagttg taggttacat
     5881 ttccatcctc atcgtattct ttatgacggt ctgcaattgg ttgcaattga acataattgt
     5941 agcccagctt cttgatgtaa tcaaaagcag ttgactggcc gtattggtta actgttccag
     6001 cctgagcagc acccaagaaa gttcctcgaa gatgttcatc tacacccgat gtaggtgatt
     6061 tagtcaaatc acgaatgtgc atttcacaga taactgcctt acatggattt tccaagcgcc
     6121 aagtagcctc cgaaccgtgc ttaacctcga agttttcaac ttgcttttct acatggctca
     6181 gaatagctga acgtttgcca tcagggctgg tcgcgattgt ataaggatca cgtgtcagtg
     6241 tttggtgatg agggaattgg acttgatact gataagcctt acctaccaaa tcttcctcaa
     6301 catccaaact ccagacaccg attgtattgt ccttatgatt atgagagtag ctattgcctc
     6361 ttttcatctc aaaagtcttc caaacgggtg catcattaac agctgattca taaacgacaa
     6421 cttgcacttc tgtcgctgta ggtgaccaga gggaaaaatg agcctgattg tcctctacac
     6481 ggcaacccaa ttctccttgg taaccccaat gatgatcaaa actagcactg ttaatggcct
     6541 tatcaaaggc aaaaggattt tgatttttat agaaaggact ggcaatagca ggattttcag
     6601 agtaataaat cctatcatcg ccttccaaaa tccagacctc tgttaatagg ggatagtgat
     6661 taaaacggat agaatattct ttactagttt gacctgtatg aaccacaaaa tttaagcttt
     6721 ctataacatg tgaacttggg tgttcaaagc taaataaagc tccaaaataa tcttctttgt
     6781 aggttagcaa atcaattcgt tgatcctgac tttttacaaa ggagcaagtg tcatattctc
     6841 cattcttacg atggtaatga atgcgcatag ggtagttata cattttttat ttttcctttt
     6901 tactttgttt ctatttcact aataaatttt tgtcaatctc gtctcaatta acagacatag
     6961 tcatattctc taaactctgt ttttaaacga tccattacaa actttctagc catgcctcat
     7021 ctctgacctg gataccaagt tcttgtgctt tttgcagttt acttccagcg tctgcaccta
     7081 ccacgacgag gtcggtcttt ttagaaacac tacctgtcac tttggcaccc agactttcga
     7141 gtttactttt agcttctgag cgcttgagtc gtttcaattt tcctgtcaat accacggtca
     7201 aacctgacaa ggccgcatcc gctactatcg tctgtccttt atagtccaga ttgaccccag
     7261 tttctttcaa ttctctgagc agaatttcag agccttctgt cgcaaaataa gtctgaagac
     7321 ttttggcaat cacgccacct agactttcaa tactggccac ttcctctgaa tctgcctgag
     7381 acagattttc aattgaatgg aaatattgaa gtaaaagctg actagccttg cttcctacat
     7441 gacgaattcc caaaccaaat aagagcttct cggcagaatt ttcctttgat gcttggatag
     7501 cctgatacag tttagcagcg gacttttcct taaccccctc taaaaggagg aaatcctctt
     7561 cttgcaaacg ataaatatcc gccacatcct tgactaaatt agcagcaaag agcttctcaa
     7621 caatagatgg accaaggcct gtaatattca tagcatcacg agaagcaaag tgaatcaagc
     7681 tttccatgat ttgagcaggg caacgcggat tgatacaacg tagggccact tcatcttcaa
     7741 agtgcaacaa gtcagagtta caacttggac agtttgtagg gatatctagt ttttcttcag
     7801 aaacccgttt ggactctacc acacgtaaaa cggcagggat gatatcacca gccttatata
     7861 caatgaccgt atcgtctttt cggatatctt tttcagcaat ataatctaca ttgtgcaggg
     7921 tcgcacggct aacagtcgta ccggcaagtt gtactggtgt tagattagca gttggagtta
     7981 caacaccggt acggccaact gtccagtcaa ctgataagag ttgagcttct ttttcttcag
     8041 cagggaactt gtaggctact gcccactttg gagccttaac tgtaaaacca agttcttctt
     8101 gacttgctag gtcgttgacc ttgattacca ctccatcaat atcgtaaggc agattttccc
     8161 gttcctgtcc tacttcttgg ataaaattcc agatttcatc tatgttttca gccaagattc
     8221 gcttaggatt gaccacaaaa cctagttgtt ctaggtactt caaccccttt tcttggctat
     8281 cacgagttga agggctggct tcttgataga gaaacgttgc aagattacgc ttggcaacta
     8341 ctgctgtatc caactgacgc agagttcctg ctgccgcatt acgaggatta gcaaattcag
     8401 gctctccatt ttcttggcgc gcttggttaa cttggtcaaa ggaagcgcgt ggcatgtaac
     8461 attccccacg aactgtgata tctagttctt ctggcaaagt caaagggatg tccttaacac
     8521 gcttgaggtt ttctgtgata ttttcaccaa ttgaaccatc tccacgtgtt accccagcaa
     8581 ccaaaatccc cttttcataa gtcagcgaga tagataagcc atcgattttc agctcacaaa
     8641 tataggtcgg atgagccact tccttacgaa cacgcgcatc aaaagcatct agctcctcac
     8701 gtgaaaaagc atcctgcaaa ctataaagag gatactgatg actgtatttt tcaaaaccat
     8761 ctaaaacctt gccaccaaca cgatgagtcg gactgtctgc tagcacttgc tctggataag
     8821 cagtttctaa ctcgaccaac ttacggtaaa ggcggtcata ctcactgtct gaaaccgagg
     8881 gattatcgct ggtatagtac tcagtcgcat agcgattgag caaagcgact aactcattca
     8941 ttcttttatt cataagacca ttttaccata aaacaaaccc tcctcacaaa cgagaagggc
     9001 ggaaaaaaca cttagtttga aattattttt gaaactcaag caaccttata tcaatttttc
     9061 aaaatgagtt cgaacataaa taaacgatat a
//
LOCUS       DAVDZK010000060         9011 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVDZK010000060 DAVDZK010000000
VERSION     DAVDZK010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9011
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.061"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(167..784)
                     /locus_tag="VUX16_001992"
     CDS             complement(167..784)
                     /locus_tag="VUX16_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET8124886.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLPIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(774..1547)
                     /locus_tag="VUX16_001993"
     CDS             complement(774..1547)
                     /locus_tag="VUX16_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET8124887.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVNVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVADLPIAPTHVVSSLAEWDFDEN"
     gene            complement(1558..2295)
                     /locus_tag="VUX16_001994"
     CDS             complement(1558..2295)
                     /locus_tag="VUX16_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET8124888.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSNFDKKLIRGPKYESLEELISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(2300..3430)
                     /locus_tag="VUX16_001995"
     CDS             complement(2300..3430)
                     /locus_tag="VUX16_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET8124889.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(3514..3903)
                     /locus_tag="VUX16_001996"
     CDS             complement(3514..3903)
                     /locus_tag="VUX16_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET8124890.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(3919..4302)
                     /locus_tag="VUX16_001997"
     CDS             complement(3919..4302)
                     /locus_tag="VUX16_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET8124891.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(4303..5091)
                     /locus_tag="VUX16_001998"
     CDS             complement(4303..5091)
                     /locus_tag="VUX16_001998"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET8124892.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(5084..6019)
                     /locus_tag="VUX16_001999"
     CDS             complement(5084..6019)
                     /locus_tag="VUX16_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET8124893.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIVILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(6149..6325)
                     /locus_tag="VUX16_002000"
     CDS             complement(6149..6325)
                     /locus_tag="VUX16_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET8124894.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(6465..7172)
                     /locus_tag="VUX16_002001"
     CDS             complement(6465..7172)
                     /locus_tag="VUX16_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET8124895.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            7323..8351
                     /gene="queA"
                     /locus_tag="VUX16_002002"
     CDS             7323..8351
                     /gene="queA"
                     /locus_tag="VUX16_002002"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET8124896.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVSTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVNN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPRYGWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
BASE COUNT         2701 a         2047 c         1664 g         2599 t
ORIGIN      
        1 aaaaataagg cgcttgacta gggattttta gaaaaaaagc ctattttttc aagaaaaata
       61 ggctgtttgc gaacgattga cacaattgga tttggttaat tcactcttaa cgatggtttt
      121 aaacgatata tatatttata tatgcaaatt aaaaacatct ttcatttcac ttcctacgac
      181 ttttcagaca cagatagcca aagaagcttt catagagggc aaaaaagagg aggaaggcat
      241 gaagaaagaa ggtctctggc aaaatcataa taacaggatc cttggctgga tcaaaaagcc
      301 aggtatcatc tcccacaaag agaatttgat ggaaaagagt aaagaattgg tcaaaaccaa
      361 tcaaaactcc cccaagtcca atcatcacag gtaagactac tagagccagg agactttttc
      421 gataaagaga caaaaagtcc tttttcacaa ttctattgac aaagacatag aaacttggca
      481 gtgtcactag agctactagc tgaaccaaat gaaagagatt cttgaccact gcgaaatggt
      541 gcagaccagc tgctgacgaa cgaaaatcag gcatctgtaa gacctgacta aaaggattgg
      601 tcagataatt catcaagata tgaaaattgt attgaatggt ttctggtttt agatagactc
      661 gattcgttaa gtttagccac tgaatctcca taggatagaa aatccaagcc agataaatgg
      721 gcagaaggat tgagagggag aggagaaaga gcatagagcc ccaaaaggtc aatttagttt
      781 tcatcaaaat cccactccgc aaggctagaa accacatgtg tcggtgcgat tggcaggtca
      841 gctacttctt ctgccttagt aaaacctgtc gtcaccaaga gcgttggaat gccattgtca
      901 atcccagccc ggatatcagt caaataattg tccccaacca taattaactc ttcacgttcc
      961 aaacctaagt gctcaaccgc cttgtccata atgatggcat ttggttttcc gatataaacc
     1021 ggcttcactc gtgtcgctac ttcaagcagc gtaatcagtg agccagcacc tggcaaaaga
     1081 ccgcgttccg tcgggatgtt gaggtcagga ttggttccga taaaatgggc acccttttga
     1141 atagcaagag ttgctgtggc aaatttttca tagtcgactt gccaatccag accaactacc
     1201 acgtaggcag gtttttcctt gtcttccaca taaccagccg ccttgatggc ttccttgagt
     1261 cctgcttctc cgacaacatt gacggtcttt tcaagcccca aatcattcat atagtcgatg
     1321 gttgccaaag tcgctgtgta gacagtcgat aggggcgtat cgatattaaa attctgagcc
     1381 aacatctcct taacactctc tggagtgcga gttgtattgt tggttacaaa gagataggga
     1441 atgtcccgct tttgcaattc atgaacaaaa gtctctccag cagggattcg gtctttcccc
     1501 ttataaatgg ttccgtctaa atcaattaaa tagcctttat atttcatcta tttctcccta
     1561 agcctttttt atttcttgcc aagtaatgat tgcttgggca ttgataaccc catcacttgt
     1621 aatttcatgc ttgctttcca gtccagtccg ttcaacagcc gatgtaatca ccccacctgg
     1681 tcgaacttcc ttgacatact tgaggttgat tttcttggga atatagtggg tcaaaaaatc
     1741 cgctcccatg acctcaaaaa tccagtccaa gtatttactg ttattgacat gaccattcat
     1801 atccaagtcg taaaaacgaa catggtaatc cttgctgatc agctcttcca aggactcata
     1861 cttcggtcca cggataagtt ttttatcaaa attagactgg taaggagcca caatctcagg
     1921 ttcaacagca tggacttttc gactgtcgcg gtccatgaga acaaaggtcg ccatcatatg
     1981 gatgagctcc tgccccgctt cattataaat agtaaagcga cggtagcaaa aaagccgatt
     2041 gtagctcaag gcttccgttt cgatggtaat ttcttccgca aaacgaggca aacgaaccac
     2101 ctcaatatca tattctgcga taatccagac cagattatag tcttccaaaa tggccttatc
     2161 actaactccc agttcaatcg actgcatccc tgaaacttgc agtgacagca aaatcacatc
     2221 tggaagtttg atatgaccgt tcatatcagc catatcaaaa ggaattttca ttttcatttg
     2281 ataagttaag cccatgatcc tactccaaaa taaatcgttc tgctacagta tctcccaaaa
     2341 agagacctct ctttgtcatg cgaacgtggt caccctcaat ctgcatgagg ccttgttgaa
     2401 ccaaatctct gacaatttct ccataaagtc cagcaaaaga ctgtccaaat ttttcctcaa
     2461 atcgcgccat ggaaaccccg gatttcttgc ggagtcccaa gaacatttct tcttccattt
     2521 gctccttttg actcaggtga tcttctgtaa tacaagcatt gccttcctca accgcactga
     2581 gataatgacg aatgggacca tgatttttat agcgtactcc attgacataa ccagatgccc
     2641 ctgcaccaat accatagtat tcagcattgt cccagtacat gagattgtga cgactttcaa
     2701 agccgggttt ggagaaatta gaaatctcat aatgctcaaa acccgctcgc tccagctctg
     2761 caatgatgta ctcaaacatc tccgcttcta gttcctcctt aggcagaggc aatttcccac
     2821 gtcgcatccg gttcataaag accgtatggt tttctaaaat caaactatac aaactcatgt
     2881 ggggaatatc cagtccaatg gctttagcca cattttcctt tacttgctcc atggtctgac
     2941 caggcagagc ataaatcaaa tcaatggaga tgttgtcaaa accagccagt ttcaggcgat
     3001 cgatattttc ataaatatcc ttctccaaat gactgcgccc aatctttttc aacatcttat
     3061 catcaaaggt ctggacacct agcgaaacac gattgacagc cgaatttttc aaaacagcta
     3121 tcttatccgc atccaaatcg cctggattgg cttcaatggt caactcttcc aagacagaca
     3181 aatccaagtt tttagtcaag ccattcagta acacctccag ttgcggagcc gacagggctg
     3241 tcggtgttcc accaccgata taaagggttg acaacttttc aatatcataa gaacgaaact
     3301 cttccagcag atgctctaaa tagctgtcga ctggctgatt tttgatgaag acctttgaaa
     3361 aatcacaata ataacaaatc tgggtacaaa atgggatgtg cacataggct gacgttggtt
     3421 ttttctgcat agtaattatt ataccacaaa gactagattc cagataaaaa tcaccatccc
     3481 cagatacata gtccgtccgg agatggtgat ggtttattct tctgttatat caatcacaat
     3541 ctcttctgag tcatcaagag cttcggcttt ttcttgccat tgctccttga gattatttaa
     3601 ttgatttttt gatgcttctg tcgcttgaaa agcataggat ttagcttgag caagtatact
     3661 gtccacagtg atttcacctg actcaacctg ttcttttgtt ttcagaacaa aatctgtagc
     3721 ctgctcctta acttctgtca gtttttcaca gacttgctcc ttggcatact ccggatcttc
     3781 tctcaaatca tctagaaaat cttgagcctg actgcaaact tgtttgccct tatcacttgt
     3841 taaaaacaag gcaagagctg cacctgaaac cgttcctaaa aggattgagg ataatttacc
     3901 cataaggatt ctcctttttt attttttgaa aaatttactt gcaagacgaa gagctgacag
     3961 acttgcacca gtcttgagtg tttttgaacc agctgatgaa gctttcttgc tcaagacacg
     4021 cgcatggtca ttgaggtctg aaacagatag agataaatct gcaacagcac tgaagagtgg
     4081 atcaatcgta gccaccttga cattgatatc atctgccaag acattgacct tagccaacaa
     4141 ctcattggtg tgatgcaagg tcacatccac atctgaagtc aaggttttaa tcgtcttttc
     4201 tgtttcatcg atgacacgac caagcttttg tacagtaatg atcagataga ccaaaaagac
     4261 aatcaaagct agggcaacaa gaatatatgc aacttctaac atttagtttt cctcctctgt
     4321 aatatagtaa ggggccttct ttcgattttg ataaataacg atcattatac cgagaccgat
     4381 aaggacaact gacagccatt gggacactcg aaggccgaag aacatgagac tatctgttcg
     4441 cataccttcg atgaccatac gaccgaaacc ataccaaatc aagtaaaagg ccgtgatatg
     4501 acctcgtctg agactcttcc atttccgtct aaaaatcaga atcaaggcaa agccaagcag
     4561 attccataga gactcataaa ggaaagtcgg ttgacggtag ctcccctcaa tatacatctg
     4621 gtcacggata aagccaggta gataatccag attatccact gttgcaccat aagcttcttg
     4681 gttaaagaaa ttaccccaac gccccaaact ttgagcaatc ataacgctag gcgccgcaat
     4741 atctagaaaa tcccaagtat tgatgagttt acggtcagca aagatataga gcacaagagc
     4801 cccagttatc aaaccaccgt aaatggccaa accaccattc caaatggcaa aaatctctcc
     4861 taaattctga ctatagtaat caaatcggaa aataacatag tagagacgag ctcctaaaat
     4921 agccaaggga aaggctacta agataaaatc taaaatatcg tctggtatga tcttctttct
     4981 aggtgcttct ttcatggtca aataaaccgc aagaatcaag cctgtcacaa tacataaggc
     5041 ataccaacga atagctaggg gtcctagttg aatagcaatt ggatcaagca ttttgcacct
     5101 catttcgagc gatgagactt gtcagtcgtt cgtcgaacaa acgggtcgca tcaaagccca
     5161 tttccttggc acgataattc atggcagctg cctcaatcac aacagagata ttacgacctg
     5221 ttttaactgg aatacgaata cgaggaatgg ctacgccaga aacttcaagt tcctctgcat
     5281 tgtttccaag acgatcaaag gtcttatgcg tatcgtaatt ttccaaatag acagcaagct
     5341 gaacctgtga agaatccttg acagcactcg caccgtagag actcataaca tcgataatac
     5401 caaccccacg aatttcaatc aagtgtttca aaatttcagc tggttcaccc cagagagtaa
     5461 tctcatcctt ggcaaagata tcgacacggt catcggctac caaacggtga ccacgtttga
     5521 caagctcaag acctgtctcg ctcttaccaa ttccactatc tccctgaatc aagacgccca
     5581 tcccataaat atccatcaag acaccgtgca cactggtacg ttctgccaaa cgagaatcca
     5641 gatagctaga taactctcca gataaacgac tggtagctgc acggctggtt aaaataacaa
     5701 tcttacattc tctagcagcc tttaacatct cctctggaac caccaaacca cgggcaacaa
     5761 tgactgctgg tgtctcaggt agaaacattt ttttcaaaac ttcataacgg ctgttggaag
     5821 gcatgctgat cagataagac cactccttca tccccaaaag ttgaatccgc tctggtgtat
     5881 agtagtcaaa atagcctgtc atttcaagac caggtcgcgt aatatccgct gtattgattt
     5941 ccttttcaag caattctggt tcgccataga caatgtctag tctaagcttt tcaatcactt
     6001 cttttactaa aaccgacatc atttcctcct tcaaatgagt tcttctctct attatatcaa
     6061 attgtaggag gaagtttcag atttttgcag gctttggagt atttatttaa aagaaaaagg
     6121 actagatttc tctagccttt catttcaatt agaatttttt acgtttacga gctacttctg
     6181 atttacgttt acgttttaca gaaggttttt catagaattc acgtttgcgt gtttcttgaa
     6241 gagtaccagc tttagtaacc gcacgtttga aacggcgaag tgcgtcgtca agagattcat
     6301 tcttacgtac tactgtttta gacatttttt tcactccctt caagttcaat atctatttca
     6361 ttctacacgt aaaaggaata attgtcaagc aaaaatgcgg tttaattttg attttttctt
     6421 ccatttatac aagagttgaa agcgttcaat agaacattgc ttttttattt ttcgagtaag
     6481 ctaagcgctt cagcatctgc gatgatggtt acatcagggt gattttggag gctacttgca
     6541 ggtaggttct cagtcactgg gccagatact gttccggcaa tggcttctgc tttcgactca
     6601 ccgtaagcaa aaagaataat agacttggca tccaaaatgt ttttaatccc cattgaaata
     6661 gcttgggttg ggacgtcttc aatcttagca aagaagcgtg cattggcttc gatagtagac
     6721 tggtcaagtt ctactagatg cgtttgactg tcaaatggag taccaggctc attaaagccg
     6781 atatgcccat tgcgaccgat tcccaagatt tggaggtcaa ctggatggtc agccaaaatt
     6841 tggttgtagc gttcaacttc agcttcagca ttgtccttaa caccacgagg caagaaactt
     6901 tctttaaatg gtttttggtt gaacaagttt tcttgcatga agtaacgata agactgtgga
     6961 ttgtccccat caaggcccac atactcatca aggttgacac tggttagatt tgaaaaatca
     7021 aggtcactct caacaatttc cttgtaaaat tcaagtgggc tacttcctgt cgcaagtcct
     7081 agagtttgag ctccattagc caatttttcc ttcaaaatct caaaagcaac ttttccacct
     7141 tgaacttggt tttcaacttt aataactttc atcttttcat cctccatttc tgtctatatt
     7201 tattatatgg tatagaccaa tttttgtcaa gtgaaaacga tttaatttct aaaaaaagag
     7261 cgtccaaact tgaaacgtgt tataatggat agtattagaa cttagaaaga atgaacagat
     7321 atatgaatac agctgatttt gatttccact tgccagagga attgattgcc caaacgcccc
     7381 ttgaaaaacg tgatgcctcc aaactcctca tcgtcaaccg tgagacagga gaaatgcaag
     7441 ataaacactt ccactctatt attgatatgc tggaacctgg tgatgccctt gtcatgaacg
     7501 acacccgagt tctccctgcc cgcctctatg gtcaaaaagt ggagacagga ggtcatgtgg
     7561 aacttctcct ccttaagaac actagtggag acgagtggga agttctggct aaacctgcca
     7621 aacgcctcaa ggtcagtact cgtatcagct ttggtgatgg ccgcctcagc gctgtcgtta
     7681 cagaagaatt gacccacggg ggacgcattg tccgctttga ataccaagga attttcctag
     7741 aagtcttgga aagtctggga gaaatgcctc tgccacctta tatccacgaa aaattagatg
     7801 accgtgaacg ttatcaaacc gtctacgcca aggaaagcgg ctctgctgca gcaccgactg
     7861 ctggtcttca cttcaccaaa gaactgctgg cagaaatcca agctaagggt gttcatctag
     7921 tctatctgac tctccatgtc ggactcggaa cctttagacc tgtttctgtg aataatctgg
     7981 acgaacacga aatgcactca gaattctacc aactttctga agaagctgct gccacccttc
     8041 gctctgtcaa agaaaatggt ggtcgtgtca tcgctgttgg aaccacttct atccgcacct
     8101 tggaaactat tggttccaag tttgatgggc aaatccaagc agattctggt tggaccaata
     8161 tctttatcaa gcctaggtat gggtggaagg tcgtggatgc cttctcaacc aacttccacc
     8221 tgccaaaatc aactctggtc atgttggttt ctgcctttgc aggccgtgaa ttagtcttag
     8281 atgcctacca ccatgccatc caagaacact accgcttctt cagttttggt gacgccatgt
     8341 ttatttattg agaaagaatt tctctaaatc ttctaatacc aataaatcgc taagatatta
     8401 tttcaaagaa catctacaat tgaaactcta gctagctata gaatacgcct agtacattga
     8461 aattaaaatg cttcccccta gcttcgaaaa tattgccata gattgcgttg actctccaaa
     8521 ttgattcatc tatattttat ttcagcttcc tatactttct tcgctgtttg taaattaaaa
     8581 tgcaagacac atgagtagca ccatatttgt tactcttatc tgtcctctca agagactgtt
     8641 atgagttatt tcagaatcat tcactacttt gaccctgact ctccttagtc tcaaaatcaa
     8701 agacttatac tcttcaaaaa tctcttcaaa ccgcgtcaac gtcaccttga attatatatg
     8761 tgaccgactt cgtcagttct atctacaacc tcaaagcagt actttgagca acctgcgact
     8821 agttttctag tttgctcttt gattttcatt gagtattaaa caaaaagtga acaaatctga
     8881 attctaatgt acagaagact aggcttgttc actttttggc tctataatat ttgtagtggg
     8941 taaatccact atagatatta tggagcctat tttattgtag aaaaaaaatc ccatatgacc
     9001 tataatgaaa a
//
LOCUS       DAVDZK010000061         8828 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVDZK010000061 DAVDZK010000000
VERSION     DAVDZK010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8828
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.062"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            66..299
                     /gene="secG"
                     /locus_tag="VUX16_002003"
     CDS             66..299
                     /gene="secG"
                     /locus_tag="VUX16_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET8124897.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            401..2755
                     /gene="rnr"
                     /locus_tag="VUX16_002004"
     CDS             401..2755
                     /gene="rnr"
                     /locus_tag="VUX16_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET8124898.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMCAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDEKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            2718..3185
                     /gene="smpB"
                     /locus_tag="VUX16_002005"
     CDS             2718..3185
                     /gene="smpB"
                     /locus_tag="VUX16_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET8124899.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            3201..4061
                     /gene="tehB"
                     /locus_tag="VUX16_002006"
     CDS             3201..4061
                     /gene="tehB"
                     /locus_tag="VUX16_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET8124900.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            4134..5087
                     /gene="coiA"
                     /locus_tag="VUX16_002007"
     CDS             4134..5087
                     /gene="coiA"
                     /locus_tag="VUX16_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET8124901.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            5106..6908
                     /gene="pepF"
                     /locus_tag="VUX16_002008"
     CDS             5106..6908
                     /gene="pepF"
                     /locus_tag="VUX16_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET8124902.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALVVLGEDYL
                     GRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            6910..7623
                     /locus_tag="VUX16_002009"
     CDS             6910..7623
                     /locus_tag="VUX16_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET8124903.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            7690..8631
                     /gene="prsA"
                     /locus_tag="VUX16_002010"
     CDS             7690..8631
                     /gene="prsA"
                     /locus_tag="VUX16_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET8124904.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGSGDSSSSSSTSNE"
     gene            complement(8748..>8828)
                     /locus_tag="VUX16_002011"
     CDS             complement(8748..>8828)
                     /locus_tag="VUX16_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET8124905.1"
                     /translation="DYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         2842 a         1621 c         1944 g         2421 t
ORIGIN      
        1 taaccctaca tcttgaatct aagtagattt tatggtaaaa taatagggat tttaaggagt
       61 ttgatatgta taacctatta ttaaccattt tattagtatt atctgttgtg attgtgattg
      121 caattttcat gcaaccaacc aaaaaccaat ctagcaatgt atttgatgcc agttcaggtg
      181 atttgtttga acgcagtaaa gctcgcggtt ttgaagctgt aatgcagcgt ttgacaggga
      241 ttttagtctt tttctggcta gccattgcct tagcattgac ggtattatca agtagataag
      301 aaaataatgg gcaggactag gtctttgcct ctttttattt ttaaaggatg tttgagaagg
      361 ttttacagta aaagaaaatt aaaaaatcta gaaagaaaat atgaaagata gaataaaaga
      421 atatttacaa gacaagggaa aggtgactgt taatgatttg gctcaggctt tgggaaaaga
      481 cagttccaag gattttcgtg agttgattaa aaccttgtcc ttaatggaaa gaaagcacca
      541 gattcgcttt gaagaagatg gtagtctgac attagaaatt aagaaaaaac atgagattac
      601 cctcaagggg atttttcatg cccataaaaa tggctttggc tttgttagtc tggaaggcga
      661 ggaggacgac ctttttgtag ggaaaaatga tgtcaactat gctattgatg gtgataccgt
      721 cgaggtagtg attaagaaag tcgctgaccg caataaggga acagcagcag aagccaaaat
      781 tattgatatc ctagaacaca gtttgacaac agttgtcggg caaatcgttc tggatcagga
      841 aaagcctaag tatgctggct atattcgttc aaaaaatcag aaaatcagtc aaccgattta
      901 tgttaagaaa ccagccctaa aattagaagg aacagaagtt ctcaaagtct ttatcgataa
      961 atacccaagc aagaaacatg atttctttgt cgcgagtgtt ctcgatgtgg tgggacactc
     1021 aacggatgtc ggaattgatg ttcttgaggt cttggaatca atggacattg tatccgagtt
     1081 tccagaagct gttgttaagg aagcagaaag tgtgcctgat gctccgtctc aaaaggatat
     1141 ggaaggtcgt ctggatctaa gagatgaaat tacctttacc attgacggtg cggatgccaa
     1201 ggacttggac gatgcagtgc atatcaaggc tctgaaaaat ggtaatctgg agcttggggt
     1261 tcacatcgca gatgtttcct attatgtgac cgagggttct gcccttgaca aggaagccct
     1321 taaccgtgcg acttctgttt acgtgacaga ccgagtggtg ccaatgcttc cagaacgact
     1381 atcaaatggc atctgctctc tcaatcccca agttgaccgc ctgacccagt ctgctattat
     1441 ggagattgat aaacatggtc gtgtggtcaa ctataccatt acacaaacag ttatcaagac
     1501 cagttttcgt atgacctata gcgatgtcaa tgatatccta gctggcgatg aagaaaagag
     1561 aaaagaatat cataaaattg tatcaagtat cgaactcatg gccaagcttc atgaaacttt
     1621 agaaaacatg cgtgtgaaac gtggagctct caattttgat accaatgaag cgaagatttt
     1681 agtggataaa caaggtaagc ctgttgatat cgttcttcgg cagcgtggta ttgccgagcg
     1741 gatgattgag tcttttatgt tgatggctaa tgaaacagtt gccgaacatt tcagcaagtt
     1801 ggatttgcct tttatctatc gaattcacga ggagcctaag gctgaaaagg ttcagaagtt
     1861 tattgattat gcttcgagtt ttggcttgcg catttatggg actgccagtg agattagtca
     1921 ggaggcactt caagacatca tgtgtgctgt tgagggagaa ccttatgcag atgtattgtc
     1981 catgatgctt cttcgctcta tgcagcaggc tcgttattcg gagcacaatc acggccacta
     2041 tggactagct gctgactatt atactcactt taccagtcca attcgtcgtt atccagacct
     2101 tcttgttcac cgtatgattc gggattacgg tcgttctaag gaaatagcag agcattttga
     2161 acaagtgatt ccagagattg cgacccagtc ttccaaccgt gaacgtcgtg ccatagaagc
     2221 tgagcgtgaa gtcgaagcca tgaaaaaggc tgagtatatg gaagaatacg tgggtgaaga
     2281 gtatgatgca gttgtatcaa gtattgtcaa attcggtctc tttgtcgaat tgccaaacac
     2341 agttgaaggc ttgattcaca tcactaatct acctgaattt tatcatttca atgagcgtga
     2401 tttgactctt cgtggagaaa aatcaggtat cactttccga gtgggtcagc agatccgtat
     2461 ccgtgttgaa agagcggata aaatgactgg agagattgat ttttcattcg tacctagtga
     2521 gtttgatgtg attgaaaaag gcttgaaaca gtctagtcgt agtggcagag ggcgtggttc
     2581 aaatcgtcgt tcggataaga aggaagacaa gagaaaatta ggacgctcaa atgataagcg
     2641 taagcattca caaaaagacg agaagaaaaa aggaaagaaa cctttttaca aggaagtagc
     2701 taagaaagga gccaagcatg gcaaagggcg agggaaaggt cgtcgcacaa aataaaaagg
     2761 cacgccacga ctatacaatc gtagatacgc tagaggcagg gatggtcctg actggaactg
     2821 aaatcaagag tgtacgagct gctcgaatta atctcaagga tggctttgct caagtgaaaa
     2881 atggagaagt ttggctgagc aatgttcata tcgcgcctta cgaagagggc aatatctgga
     2941 accaggaacc agaacgtcgt cgtaaactcc tgctccataa aaagcaaatt caaaaattgg
     3001 aacaagagac caaagggaca ggaatgacct tagttcccct taaggtctat ataaaagatg
     3061 gctacgctaa gcttctttta ggacttgcca aagggaagca tgactatgac aaacgggagt
     3121 ctatcaaacg tcgtgagcaa aatcgagata tcgcgcgtgt gatgaaagct gttaatcagc
     3181 gataaaaaga ggaattgaaa atggaaaaat tagttgccta taaacgcatg cctttgtgga
     3241 ataaacaaac aatgcctgaa gctgttcagc aaaagcacaa tacaaaagtt gggacttggg
     3301 ggaaaattac tgtcttgaag ggagctctca agtttattga attgacagaa gaaggggaag
     3361 ttctagctga acacctcttt gaagcagggg cagacaatcc aatggcccaa cctcaagcct
     3421 ggcaccgagt ggaagctgcc acagatgatg tggaatggta cttggaattt tattgtaaac
     3481 ctgaggatta ttttgctaaa aaatacaata ccaatcctgt tcattcagag gtcctagagg
     3541 ccatgcagac agtgaaacaa gggaaagctt tggatttggg ttgtggtcag gggcgtaatt
     3601 ctctttttct agcccagcaa gattttgatg tgacggctgt agatcaaaat ggactagctc
     3661 ttgaaatctt gcaaagcatt gtggagcagg aagatttgga catgcctgtt ggcctttacg
     3721 atatcaattc agctagcatt gaacaagaat atgattttat cgtttcaaca gttgttctca
     3781 tgtttctaca agcggaccgc attccagcta ttattcaaaa tatgcaggag aaaaccagtg
     3841 ttggtggtta caaccttatc gtttgtgcca tggacacgga ggattatcct tgctcggtta
     3901 acttcccatt cacctttaaa gaaggagaac tggcagacta ttacaaggat tgggaattgg
     3961 ttaagtacaa tgaaaatcca ggccatttgc accgtcgcga tgagaatggc aatcgtattc
     4021 aactacgctt tgcgacctta ctagctaaga aaatcaagta aacacacatg aagattagga
     4081 attttcctga tcttttttct tttttacgaa tgatatagaa aaggagggaa ttcatgtttg
     4141 ttgcgagaga tgctagggga gaattggtaa atgtgttaga ggataaactt gagaagcaag
     4201 catacacctg cccagcttgt ggaggccagc tccatttgcg tcaaggacca agtgtacgga
     4261 cgcattttgc ccataaatcc ttaaaagact gtgatttttt ctttgaaaat gaaagtccag
     4321 aacacctggc caataaggaa tccctctatc actggttgaa aaaagagaca aaggttcaat
     4381 tagagtaccc gctttcagaa cttaaacaga ttgcggatgt atttgtaaat ggcaatctag
     4441 ctctagaagt tcagtgtagt cccttgcctc agaaagtcct taaagagcga agtgagggct
     4501 atcgtagtca gggttaccaa gtactgtggt tgctgggtca aaaactgtgg ctcaaggagc
     4561 gtttgactcg tctacagcaa ggttttcttt atttcagtca aaacatgggc ttttatgttt
     4621 gggaattaga caaggaaaaa caagttttaa gactcaaata cctgatttac caggatctcc
     4681 gcggtaaact ccattatcaa atcaaggaat tttcctatgg tcaaggtagt ttattggaaa
     4741 tattgcgtct tccctataag agacaaaaaa tatctcattt tacagtttct gaggacaagg
     4801 acatctgtcg ctatatccgg caacaacttt attatcaaaa tctcttttgg atgaaagaac
     4861 aagcagaagc ctatcaaaag ggagaaaata tcctgactta tggactgaaa gaatggtatc
     4921 cacaaattcg accaatagtg ggcaaatttt tccagattga acaagacttg actagctatt
     4981 atcagcactt ttatacctat taccaaaaaa atcctcaaaa tgattggcaa aagctttatc
     5041 caccagcctt ttatcagcaa tatttcttga aaaatatggt agaatagaaa ggatggagga
     5101 atctaatggt attacaaaga aatgaaataa atgaaaaaga tacatgggat ctatcaacga
     5161 tctacccaac tgaccaggct tgggaagaag ccttaaaaga tttaacagaa caattggaga
     5221 cagtagccca gtatgaaggc catctcttgg atagtgcgga taacctacta gaaatcactg
     5281 aattttctct tgaaatggaa cgccagatgg agaagcttta cgtttatgct catatgaaga
     5341 atgaccagga tacacgtgaa gctaagtatc aagagtacta tgccaaggcc atgacactct
     5401 acagccagtt agaccaagcc ttttcattct atgagcctga atttatggag attagcgaaa
     5461 agcagtatgc tgacttttta gaagctcaac caaagctgca ggtttatcaa cactattttg
     5521 acaagctctt gcaaggcaag gatcacgttc tctcacaacg tgaagaagaa ttattggctg
     5581 gagctggaga aatctttggt tcagcaagtg aaaccttcgc tatcttggac aatgcggata
     5641 ttgtgttccc ttatgtccta gacgatgatg gtaaagaagt tcagctatct catgggattt
     5701 acacacgttt gatggagtct aaaaaacgtg aggttcgccg tggtgcctat caagctcttt
     5761 atgcgactta cgaacaattc caacacacct atgccaaaac cttgcaaacc aatgttaagg
     5821 tgcaaaatta ccgtgctaaa gttcgtaact acaagagtgc tcgtcatgca gccctcgcag
     5881 cgaattttgt tccagaaagt gtttatgaca atttggtagc agcagttcgc aagcatttgc
     5941 cactcttaca tcgctatctt gagcttcgtt caaaaatctt ggggatttca gatctcaaga
     6001 tgtacgatgt ctacacaccg ctttcatctg ttgaatacag ttttacctac caagaagcct
     6061 tgaaaaaagc agaagatgct ttggtagtct tgggtgagga ttacttgggc cgtgttaaac
     6121 gtgccttcag cgagcgttgg attgatgttt acgaaaatca aggcaagcgt tcaggtgcct
     6181 actctggtgg ttcttacgat accaatgcct ttatgcttct caactggcag gacaatctgg
     6241 acaatctctt tactcttgtt catgaaacag gtcacagtat gcattcaagc tatactcgtg
     6301 aaactcagcc ttatgtttac ggagattact ctatcttttt ggctgagatt gcctcaacta
     6361 ccaatgaaaa tatcttgacg gagaaattat tggaagaagt ggaagacgac gcaacacgct
     6421 ttgctattct caataacttc ctagatggtt tccgtggaac agttttccgc caaactcaat
     6481 ttgctgagtt tgaacacgcc attcaccaag cagatcaaaa tggggaggtc ttgacaagcg
     6541 atttcctaaa taaactctac gcagacttga accaagagta ttatggtttg agtaaggaag
     6601 acaatcctga aatccaatac gagtgggctc gcattccaca cttctactat aactactatg
     6661 tatatcaata ttcaactggc tttgcggccg cctcagcctt ggctgaaaaa attgtccatg
     6721 gtagtcaaga agaccgtgac cgctatatcg actacctcaa ggcaggtaag tcggactatc
     6781 cacttaatgt catgagaaaa gctggtgttg atatggagaa ggaagactac ctcaacgatg
     6841 cctttgcagt ctttgaacgc cgtttaaatg agtttgaagc ccttgttgaa aaattaggat
     6901 tggcataaaa tggttgaatc gtatagtaag aatgctaacc ataacatgcg tcgtcctgtc
     6961 gtcaaagaag aaattgtaga cttgatgcgt cagcgtcaaa agcaagtcac aggtttcttg
     7021 aaagaattgg aagattttgc ccgcaaggaa aatattccta ttattcccca tgaaacggtt
     7081 gcttatttcc gttttcttat ggaaaccatg cagcctaaaa atattctgga aattgggacg
     7141 gctatcggtt tttcagctct cttgatggct gaacatgcgc caaatgctaa gattacaact
     7201 attgatcgta atccagaaat gattggtttt gccaaggaaa attttgccca gtttgacagt
     7261 cgcaagcaaa tcactctcct agagggagat gcggtggatg tcttatctac actgacagag
     7321 tcttatgatt tcgtctttat ggattctgcc aagtctaaat acatcgtctt tctgccagaa
     7381 atcctcaaac atttggaagt tggtggtgtg gttgtcttgg atgatatttt tcaaggtggt
     7441 gatgttgcca aggatattat ggaagtccgt cgtggtcagc gaaccattta tcgaggcctt
     7501 caaaaattat ttgatgcaac cttagacaat ccagaactca ccgcaacatt agtgccttta
     7561 ggagatggta ttctcatgct tcgtaaaaat gtagcagatg ttcaactgtc tgaaagcgaa
     7621 tgattttcag aaaaatttaa gaaaaaatag taaaatagat agagtaacac ttatctcaaa
     7681 ggagtagaca tgaagaaaaa attattggca ggtgccatca cactattatc agtagcaact
     7741 ttagcagctt gttcgaaagg gtcagaaggg gcagacctta tcagcatgaa aggggatgtc
     7801 atcacagaac atcaatttta tgagcaagtg aaaaacaacc cttcagccca acaagtcttg
     7861 ttaaatatga ccatccaaaa agtttttgaa aaacaatatg gctcagagct tgatgataaa
     7921 gaggttgatg atactattgc cgaagaaaaa aaacaatatg gcgaaaacta ccaacgtgtc
     7981 ttgtcacaag caggtatgac tcttgaaaca cgtaaagctc aaattcgtac aagtaaatta
     8041 gttgagttgg cagttaagaa ggtagcagaa gctgaattga cagatgaagc ctataagaaa
     8101 gcctttgatg agtacactcc agatgtaacg gctcaaatca tccgtcttaa taatgaagat
     8161 aaggccaaag aagttctcga aaaagccaag gcagaaggtg ctgattttgc tcaattagcc
     8221 aaagataatt caactgatga aaaaacaaaa gaaaatggtg gagaaattac ctttgattct
     8281 gcttcaacag aagtacctga gcaagtcaaa aaagccgctt tcgctttaga tgtggatggt
     8341 gtttctgatg tgattacagc aactggcaca caagcctaca gtagccaata ttacattgta
     8401 aaactcacta agaaaacaga aaaatcatct aatattgatg actacaaaga aaaattaaaa
     8461 actgttatct tgactcaaaa acaaaatgat tcaacatttg ttcaaagcat tatcggaaaa
     8521 gaattgcaag cagccaatat caaggttaag gaccaagcct tccaaaatat ctttacccaa
     8581 tatatcggta gtggagattc aagctcaagc agtagtacat caaacgaata gtccaaatca
     8641 atgagtcagg gaaaaaactc gacttcagga aaaaatgaag caaacattcc cacaataaaa
     8701 cgcatagtac aaggtttgta ctgcccccca aaagttagac aattaattta tccgaaggac
     8761 ttagttctgt attgcacagg gctaagtcct tttagtttta ccttaattct cttattgttg
     8821 taataatc
//
LOCUS       DAVDZK010000062         8226 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVDZK010000062 DAVDZK010000000
VERSION     DAVDZK010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8226
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.063"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(410..562)
                     /gene="cibB"
                     /locus_tag="VUX16_002012"
     CDS             complement(410..562)
                     /gene="cibB"
                     /locus_tag="VUX16_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET8124906.1"
                     /translation="MMKDLNNYCEISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(564..749)
                     /gene="cibA"
                     /locus_tag="VUX16_002013"
     CDS             complement(564..749)
                     /gene="cibA"
                     /locus_tag="VUX16_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET8124907.1"
                     /translation="MINFDVLDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            927..1610
                     /gene="tsaB"
                     /locus_tag="VUX16_002014"
     CDS             927..1610
                     /gene="tsaB"
                     /locus_tag="VUX16_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET8124908.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            1607..2044
                     /gene="rimI"
                     /locus_tag="VUX16_002015"
     CDS             1607..2044
                     /gene="rimI"
                     /locus_tag="VUX16_002015"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET8124909.1"
                     /translation="MIEIKRIQQQPALAQAIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLTVQETLFEAEVLQIAVKGACQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            2034..3044
                     /gene="tsaD"
                     /locus_tag="VUX16_002016"
     CDS             2034..3044
                     /gene="tsaD"
                     /locus_tag="VUX16_002016"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET8124910.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAEITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDMYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNSEQKGESLSAEDLCASFQAAVLDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLATEITDVNVMIPPLRLCGDNAGMIAYASVSEWNKENFASLDLNAKPSLTFDT
                     IE"
     gene            3148..4011
                     /locus_tag="VUX16_002017"
     CDS             3148..4011
                     /locus_tag="VUX16_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET8124911.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLIASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRKVVDRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            4180..4406
                     /locus_tag="VUX16_002018"
                     /pseudo
     CDS             4180..4406
                     /locus_tag="VUX16_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849794.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4491..6876
                     /locus_tag="VUX16_002019"
                     /pseudo
     CDS             4491..6876
                     /locus_tag="VUX16_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375503.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
     gene            6876..8102
                     /locus_tag="VUX16_002020"
     CDS             6876..8102
                     /locus_tag="VUX16_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET8124912.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFPLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVTQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         2628 a         1373 c         1632 g         2593 t
ORIGIN      
        1 aagagaatta aggtaaaact aaaaggactt agtcctgtgc agtacagaac taaatccttt
       61 gaataaatta tttgtctaac tttttggggg cagtacatat gctggggctt tttgtttgag
      121 gatatagaga tagtagattt acgacacgaa aattccaccc catctatcaa gatgaggtga
      181 tctttgcatt tttctaaaat gacatgacaa tggaattttc agagcttatt atttttatgg
      241 gagtcattgt tctgctcaaa aatagagttg aagcataaaa ataaaacaat acaaacagat
      301 agatcaattg gtaaagggat agtagtcatg tttaaatcat tgagaatgct gagcaaactg
      361 taagagatga agacaataaa atttatcctt ctaaaaatgt gtttcttatc tagcatgact
      421 taccaaactt tttacgaagg tcttttccaa tggtataacc tgccataaat aaagcgatac
      481 caacacctac accaaagcca ccctttattt cttgcaattc cttattagaa atttcacaat
      541 agttgttcaa atctttcatc atattaatct cctcctaaaa aataaccagc tgccaaacca
      601 gaacctataa gtgctgttcc acctgcaata gctttccaag atactgctac tccaaagata
      661 accaagggag cgagaccgcc atcaatatct gataattcat tttcagataa ggataaaaat
      721 tgattgtcaa gaacgtcaaa atttatcatt gaactttcct ccttttttct tgttcacttt
      781 tatattcgta aaagaaaagg aaaagtgagc atttttttaa attattttta gttaagtgag
      841 ggcactcttg tctgggggca aagaaaattc ccatgtgcca gcttttgtag tataatagta
      901 agcagataaa aagataggaa tgtgttatga aagtattagc ttttgatacg tccagcaagg
      961 ctctttctct ggctatttta gaggacaagc aggttcttgc cgagacgacg attaatatca
     1021 agaaaaatca cagcattacc cttatgcctg ccatcgattt tttgatggca agtttggatt
     1081 ggacacccaa ggatttagac cgaatcgtgg tggcggaagg accaggtagc tatacaggct
     1141 tgcgaattgc ggtagcaact gccaaaactc tggcttatac tctgaatatc gagttggttg
     1201 gtatgtcgag tctcttggct ctggtgcctt accaacaaga aggtttgttt gtccccttga
     1261 tggatgcgcg tcgcaataat gtttatgcag gattttatga aaatgccaaa cctgtcatgg
     1321 cagaagcaca tctgcctttt gagagagtca ttgagctaat caagggcgct agtcaggtaa
     1381 cctttgtcgg agaagttggc ccctttgttg agcagattca aaaacacttg ccaaggactg
     1441 attacaaaga aacattgccc aatgcagcta atctagctct tttggcctgg gacaaggaag
     1501 cagactcctt gcatgatttt gtgccaaatt acctcaaacg tgttgaggca gaggaaaact
     1561 ggctcaagaa ccataccgag tctggtgagt cctacattaa acgcctatga tagaaatcaa
     1621 acgaatccaa cagcaacctg ccttggctca agctatctac gctgtcatgg cagctgttta
     1681 cccagtcagt ccttggacac tagaacaaat ccaagcagat ctgtcccaag accagacttg
     1741 gtatgctcta gcttatgatg gggcagaagt gattggcttt ctaactgttc aggagactct
     1801 ctttgaagca gaagtcctgc aaatcgctgt caaaggagcc tgtcagggtc agggaattgc
     1861 gtcagcttta tttgctcaat tgccgacaga taaggagatt ttcctcgaag tcagaaagtc
     1921 aaatcaacga gcgcaagcat tttacaagaa agaaaagatg gcggtcatcg cggagcgaaa
     1981 agcctactac catgacccag tcgaggacgc cattatcatg aagagagaaa tagatgaagg
     2041 atagatatat tttagcattt gagacatcct gtgatgaaac cagtgtcgcc gtcttgaaaa
     2101 acgacgatga gctcttgtcc aatgtcattg ctagtcaaat tgagagtcac aaacgttttg
     2161 ggggcgtagt gccagaagta gccagtcgtc accatgtaga ggtcattaca gcctgtatcg
     2221 aggaggcgct agcagaagca gagattacag aagaggacgt gacagctgtg gcggttacct
     2281 atggaccggg cttggtcgga gccttactag ttggcttgtc agctgccaag gcctttgctt
     2341 gggctcatgg acttccgctg attcctgtga accacatggc gggtcatctc atggcagctc
     2401 agagcgtgga gcctttggag tttcccttgc tagccctatt ggtcagcggt ggacacacgg
     2461 agttggttta tgtttctgag gctggtgatt acaagattgt tggagagacc cgagatgatg
     2521 cggttgggga ggcctatgat aaggttggcc gcgttatggg cttgacctat ccagccggtc
     2581 gcgagattga cgagctagct catcaggggc aggatatgta tgacttccct cgtgctatga
     2641 tcaaggaaga caatctggag ttttcattct caggtttgaa gtctgccttt atcaatcttc
     2701 accacaattc cgagcaaaag ggagaaagtc tgtctgcaga ggacttgtgt gcttccttcc
     2761 aagcagctgt cttggatatt cttatggcaa aaactaagaa ggctttagag aaataccctg
     2821 ttaaaaccct tgtcgtggca ggtggcgtgg cagctaataa aggtctcaga gaacgcctag
     2881 caactgaaat cacagatgtc aatgttatga ttccacctct gcgtctctgc ggagacaatg
     2941 caggtatgat tgcctatgct agcgtcagcg agtggaacaa agaaaacttt gcaagtttgg
     3001 atctcaatgc caaaccaagc ctcacttttg ataccataga ataaagagtc agcttagggc
     3061 tggctgtttt atttttctaa ctatcagaat attttgacaa atgaacacaa ataatgatat
     3121 aatatgcaaa agctaggagg tggtaggatg attgaaaaaa tggaattggg agaattttac
     3181 aaggaactgc gcctggcgag aaagctcaag cagtcagatg tggcttgtga cgggctaata
     3241 gcttctcagt tgtccaagtt tgagctaggg cagtccatgt tgtctgctga taagctcata
     3301 ttagccattc aagggatcaa tatgaatttt gatgagtttg ggcacaagct caacaactat
     3361 caagaatctc cacatatgcg aatcggtcga aaggttgtgg atcgctttgc ccatcaggat
     3421 atagctgctt tagagcagct attggaggaa gtcgatcaag aacagatggc gcagacctat
     3481 cgtcgtttga atgccattgt gattaaaaat gcactccatt ccttagataa aagctacccg
     3541 ctaacagagg aggatagcga gtttttgact acctacctct acgctattga gtcttggacc
     3601 tggtttgaac tctatctttt ttgcaatact atgcccttct tgagcaatca agatctgatc
     3661 tttttatcaa cctccttact cgaaaaatcc aaggaattta aagagttagt acacaatcga
     3721 tggtatatga aaagtggtta tcttaatatc atctcagaac ttatggagcg caagctattt
     3781 tcttatattc caatctttga agctgagctg gagcgcatgc tccgtccata cgatgttttt
     3841 gaaaaagtat tgtggcagtt tttaaagaaa atgcagattt ttcttcaaac caaaggaagc
     3901 aatcaaaaag agattgaaca ctttatccaa tctctgcaag tattagaaaa tccacaattg
     3961 acagcccttt ttgaattgcg tttgcagcaa tacaaagagc ttatcgatta gttagaaatg
     4021 ggaaaaagat aataatatca gcaacgatcg tcaataatgt taaaacttgt ttcttcatat
     4081 tacttccctc ctcattagta ataactttat tataccaggg aaataatcaa atctaccaaa
     4141 atcgcaaatc tgaaatttct ataagaaaaa atatcaaata tgcgattttc taaaataagc
     4201 caattttcgt gttataattt tcgtgttata ctgtacttgt aaagcacttg aagcaaatcc
     4261 taggtcgcag aagtggttta caaaaaaata atcaaaggag aaaagaaatg cataatctaa
     4321 tggaacttga attgttacct gaagagccag taattactgt atcacgggaa gtttgtaagt
     4381 ggacttgctc atttactgct ctttaagaat aactggttaa aattaaggat agttgattac
     4441 taattaacta tccttaattt catttcagag ataatgtatt tattatattt atggatagat
     4501 tacaaacaat gctgaataaa atacaagttg atacttacca taaaaatgga tggttatttg
     4561 tgaagtatag taacaataaa cttacacagg gatggaaact tcatgtaagc agtcaactaa
     4621 aagacgcttg taatattttt tatattgttg cacaagagct ggaaaaggaa agatgtaact
     4681 acaaagttct agattgtttg gatgagttaa aaaaattaaa ttctcctagg gaagtttctc
     4741 ctactgcaaa taagtttatc actatatatc cgtctagtag gaagcaggcc aaacgaataa
     4801 tattaaatct aaaagaaaag ttagaaaaat ataaagctcc aaggatttta tcagattttc
     4861 aatgtggtga gtattctcca atacattata gatatggtgc gtttaaagca attaaaaatt
     4921 acaatttttc tgaaaataaa attgtctaca tgatgaaaaa tagtagagga gaattagtag
     4981 aagatctgag attaagttat ccatatttgc cagaaggggt taaggattta tttactgata
     5041 tggaaaaaaa taaattattt aaaccctccc cggaaatccc agagaatcac cctttaaatc
     5101 actataatat cgagtgtatt ctaaaaaaat ccaatagagg aaatgtttac agagctatag
     5161 aaaaaagtag taatcagaaa gtgataataa gacacgcacg gccatatgtt tatagttgga
     5221 atgatggttt ctctgcaatt gatgaattaa agagtgaagc agcaaattta aaagtatttc
     5281 aggataagtc ctatacaaca gatttaattg aagagtttta tgtcaatgaa gattacttcg
     5341 tagtacagaa gtttatacca ggatataatt tttttgattt aaaaaatatt gatatcgaaa
     5401 aaaatgtaat cattaataat ataattgata ttattaatga tattcatgct gagggatatt
     5461 tagcagtgga tatttctcca acaaacttta tattggatga ttttggtcgt gttaggttaa
     5521 tagacttaga aaattttaca aacaaaaaca atactgttag aagggctgct acaaaattca
     5581 tgataaatac tgattgtccc tcaaaaatct gtaccattca acaggattat tttgcacttg
     5641 caatgttgag ttttgctatt atgcgcgagc atgttttaat atttgaagga gaggacgtct
     5701 tattaaatat aactgcttta gataaaatca agttttgtat gtatattgag aaagaaattg
     5761 ggaacataac taaatcgcaa tttaattggt tgatgtattt attgaattta agtgaacaag
     5821 agaagttaga ccgattcgag aagatgaagt atataaacga ttttgaagat aaaaatatag
     5881 aatttcattt aaagaaagtt gattcctcat tcaatcttca aattgaaaat gaaacgctta
     5941 ttaactatct tctttcgtta aatatgaata gagaaagcag gatactaaat tcaaatgaat
     6001 ttggagaatt tgttagtcca atatcgtttc aacatggctt atcaggatat ttgttttatt
     6061 tatcacatat gagagacatt tctgagaatg gtagaattat cgagtggatt atctctgaag
     6121 gaaatcaaaa taaaggaaat gtgtatctaa atggttgttc aattttattt ggttcttccg
     6181 gatatctttg ggtattatta gagttctata aaaaaattac cagcaacaat ccaagtagag
     6241 aattgatcat agataaaatt agagatattt ataaagactt gataagtagt tatcaaaaag
     6301 ttgaagtatt tgactttgct ttaggaaagt caggtatttt attgagtctt atgaaatact
     6361 gtataaattt caatgatgtc gatagtatgg aatttattag agaaaaaata gaggagttat
     6421 atttatattt tgtagatgag atacgaaatg ttaatagttt aaaagaatgt aattttgcac
     6481 atggtctagc tggaattgca tacgtaattt taatttataa ttcggaattt gaattcaagg
     6541 tagcttacga aaatagtatt aaggtattca ataatctgtt agaaaatttg ttagaaaatg
     6601 aatatagtag actaaatgca actcctacaa atttagaact atcgtggtgc gaaggaactt
     6661 caggaatctt actttatttt gagttattat atgacaatac gtgagaatgt gattgagatt
     6721 ttattaagta gatccaaaag agataaaaat ggtattttgg tatttgaatg tgaagaaagt
     6781 tcagatacat tatttgattt tggtatcgga aatctaggga tttattggtc tatccttggg
     6841 gaaagattcc catttgaact taagaaggag ttgtgatgaa agtatttctt caaaatagag
     6901 attttaggca attaactatc aaccagtgga tttcaacgct tggggatacg attttttatc
     6961 tggccttcct gaattatgtg gcagatgcat cttttgcccc tttggcgatt ttactcatca
     7021 cgatttcaga aaccctgccc caagttctac aaatctttct gggagttttg gcggattttc
     7081 aacatcatcg tgtcttgaaa tacacagtca ttagttttgc aaaatttttg ctttactcta
     7141 tagtgtcttt atcactttca gggcagtcct ttcccttgtt attagtagca tttatttgtc
     7201 tgattaacct cttgtctgac acgttgagtt atttttcagg cgccatgctc actccgattt
     7261 tcattagaat tattgggcaa gaccatctgg cagaagctat tggatttaaa cagtcaactg
     7321 ttagtttagt gaaaacaatc agtaatattc taggaggagt cttattaggt attctatcca
     7381 tccagtttat ttccttgctg aacgctctta cctttttaat cgcattttta ggtatcctct
     7441 tcataaaaac tgatctcttg aaagtagaaa aaacgattaa ctatcaagaa ggactctctg
     7501 taaaatcctt ttgccagcat ttgctccaat catcgaaatt gatatggaat atgaataagg
     7561 tgctcttggt tttgtttatt atctctacta gtcaagcagt gataaatgtt acagttcctg
     7621 tctctactct atttttgagg aatcaaccct ttttgaattt acaaacaggt caatctcttg
     7681 ccttgctatc cacttttgaa ctgtcagccc tgattgtcgg aagccttgta agtggctatc
     7741 tgcaacatac catttccata aaaacagctc tctatgcctc acttgtcacc cagttgcttc
     7801 ttctagtagg atttgccaca gttcgttttg actggattct catctttagt accttggatg
     7861 cctttttcgc aggtgttctc tctcctagat tgcaagaact cgtttttaaa caaatacctg
     7921 aggagtcaat gggagcagtt caatcctcta tcggtgccat tacggttgtt ttacctagct
     7981 tatttacaat agctttggta accattgcta ctagctttgg aactctggca gttagctttg
     8041 ttttattgct atttcttcta gttgcctttg ttatgcttct gaatattcgt gaaagtattt
     8101 agtggagaat ttctataata tatgtttgag actggattgc cagccttttt atgatggtca
     8161 aaatcaacag acttttttct cttttctgaa tgtgttataa tagactgaat ctgaaatagt
     8221 acgaaa
//
LOCUS       DAVDZK010000063         7813 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVDZK010000063 DAVDZK010000000
VERSION     DAVDZK010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7813
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.064"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            52..1752
                     /gene="dnaG"
                     /locus_tag="VUX16_002021"
                     /pseudo
     CDS             52..1752
                     /gene="dnaG"
                     /locus_tag="VUX16_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014178.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
     gene            1830..2939
                     /gene="rpoD"
                     /locus_tag="VUX16_002022"
     CDS             1830..2939
                     /gene="rpoD"
                     /locus_tag="VUX16_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET8124913.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVVPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            2953..3282
                     /locus_tag="VUX16_002023"
     CDS             2953..3282
                     /locus_tag="VUX16_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET8124914.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            3397..4440
                     /gene="cpoA"
                     /locus_tag="VUX16_002024"
     CDS             3397..4440
                     /gene="cpoA"
                     /locus_tag="VUX16_002024"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET8124915.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGISREKVSYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPVALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            4456..5781
                     /locus_tag="VUX16_002025"
     CDS             4456..5781
                     /locus_tag="VUX16_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET8124916.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            5810..5986
                     /locus_tag="VUX16_002026"
     CDS             5810..5986
                     /locus_tag="VUX16_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET8124917.1"
                     /translation="MRSGRDKKIAGVCAGVAHYFDMDPTIVRVIWGVLAFGYGAGVIA
                     YIILWIIAPVVTDY"
     gene            6045..6179
                     /locus_tag="VUX16_002027"
     CDS             6045..6179
                     /locus_tag="VUX16_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET8124918.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            6243..7553
                     /gene="obgE"
                     /locus_tag="VUX16_002028"
     CDS             6243..7553
                     /gene="obgE"
                     /locus_tag="VUX16_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET8124919.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGGDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            7563..7721
                     /locus_tag="VUX16_002029"
     CDS             7563..7721
                     /locus_tag="VUX16_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124920.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT         2345 a         1386 c         1839 g         2243 t
ORIGIN      
        1 tttacttttt ttctgaaata aagtatacta tataaagtaa actatgataa catggaggta
       61 ttgtgtatgg ttgacaaaca agtcattgaa gaaatcaaaa acaatgccaa cattgtggaa
      121 gtcataggag atgtgatttc tttacaaaag gcaggacgga actatctagg gctctgtcct
      181 tttcatggtg aaaaaacacc ttctttcaac gttgtagagg acaagcagtt ttaccactgt
      241 tttggttgtg gtcgctctgg tgatgtcttt aagttcatcg aggagtacca aggggttccc
      301 tttatggaag ccgtccaaat cttaggtcag cgtgttggaa ttgaggttga aaaaccgctt
      361 tatagtgaac agaagtcagc ttcgcctcac caagctcttt atgatatgca cgaagatgca
      421 gccaaatttt attacgctat tctcatgaca acgactatgg gagaagaggc gagaaattac
      481 ctttatcagc gtggtttgac agatgaagtg ctgaaacatt ttcggattgg tttggcacca
      541 ccagaacgaa actatctcta tcaacgtttg tctggtcagt accgtgaaga agatttcttg
      601 gattcaggcc tgttttacct ctcggatgcc aatcaatttg tagacacctt tcataatcgc
      661 attatgtttc ccctgacaaa tgatcaggga aaggtcattg ccttctcagg tcgtatctgg
      721 cagaaaacgg attcacaaac ttctaagtat aaaaatagcc gatcgactgc aatttttaac
      781 aaaagttacg aattatatca tatggatagg gcaaaaaaat cttctggtaa aaccagtgag
      841 atttacctca tggaaggatt catggatgtc attgcagcct atcgggctgg aatcgaaaat
      901 gctgtggcat ctatgggaac ggccttgagt cgtgagcatg ttgagcatct gaaaaggtta
      961 accaagaagt tggttcttgt ttacgatggc gataaggctg ggcaagccgc gactttgaaa
     1021 gcgctggacg aaattggtga tatacctgtg caaattgtca gcatgcctga taacttggat
     1081 ccagatgagt atctacaaaa aaatggacca gaagacttgg cctatctatt aacgaaaact
     1141 cgtattagtc cgattgagtt ttacattcac cagtacaaac ctgaaaatag tgaaaatctg
     1201 caggcccaga ttgagtttat tgaaaaaata gctcccttga ttgttcgaga aaaatctatt
     1261 actgctcaaa acagctatat tcatatttta gctgacagtc tggcgtcctt tgattatgct
     1321 cagattgagc agattgttaa tgagagtcgt caggcgcaaa ggcagaatcg catggaaggg
     1381 gtttccagac cgacgccaat cactatgcct gtcaccaagc agttatcggc tattatgagg
     1441 gcagaagctc atctacttta tcgaatgatg gaatctcctc ttgttttgaa cgattaccgt
     1501 ttgcgggaag actttgcatt tgccacacct gaatttcagg tcttatatga cttgcttggt
     1561 cagtatggca atcttcctcc agaagttcta gcagaacaga cagaggaagt tgaaagatct
     1621 tggtaccaag ttttagctca ggatttacct gctgagatgt caccgcggga actaagtgaa
     1681 gtagaaatga ctcgaaacaa ggctctcttg aatcaggaca atatgagaat caaaaagaag
     1741 gtgcaggaag ctagccatgt aggagatacc gacacagccc tagaagaatt ggaacgttta
     1801 atttcccaaa agagaagaat ggagtaataa tggcaacaaa acaaaaagaa gtaacaacat
     1861 ttgacgtaca agtagcagaa tttatccgta atcataagca aaaagggaca gcaacagatg
     1921 atgaaatcaa tgctagtctt gtcgttcctt ttaccttgga cgctgatggg attgaagatc
     1981 tcttgcaacg gattcaggat gcgggaattt ctatcacaga taacgaagga aatccaagtg
     2041 cgcgtgttct tagcaatgaa gaagaaccag aactcagcga tgaggacttg attgggtcaa
     2101 cttctgctaa ggtcaatgac cctgtccgta tgtacttgaa agaaataggg gtcgttcctc
     2161 tcttgaccaa tgaagaggag aaagagttgg cactggctgt tgaagctggt gatatcgaag
     2221 ccaaacaacg tcttgcggaa gccaatcttc gtttggttgt ttccattgcc aaacgctatg
     2281 tcggtcgtgg catgcagttc cttgacttga ttcaagaagg aaatatgggc ttgatgaagg
     2341 cggttgacaa gtttgactat tctaaagggt tcaagttttc aacttatgca acttggtgga
     2401 ttcgtcaggc tatcactcgt gctattgcgg atcaagctcg taccatccgt atcccagttc
     2461 acatggttga aactatcaat aaattggttc gtgaacagcg gaatctcctt caagaattgg
     2521 ggcaagatcc gacaccagaa cagattgctg aacgaatgga tatgacacct gataaggttc
     2581 gtgaaatctt gaagattgcc caagaaccag tatctcttga aactcctatc ggtgaagagg
     2641 acgatagcca ccttggagac tttatcgaag atgaagtgat tgaaaatcca gtggattata
     2701 cgactcgtat cgtcttgcgt gagcaattgg atgaaatctt agatactctt acagaccgtg
     2761 aagaaaatgt tctgcgtcta cgttttggac tagatgatgg aaaaatgcgc acacttgaag
     2821 atgtggggaa agtctttaac gtaactcgtg agcgtatccg tcagattgaa gcaaaggctt
     2881 tgagaaaact acgccaacca agtcgcagca aaccgcttcg tgattttatt gaagactaag
     2941 agtgaggaaa atatggctta tacagaagag caaattgaaa acatcaaaac acggatttta
     3001 acagccttgg aagaagtcat cgaccctgag ttgggaatcg atattgtcaa tcttggtttg
     3061 atctatgaga ttcgttttga cggtgacaca gggcaaacag agattgacat gactttgaca
     3121 actatgggtt gtcccttagc agaccttttg acagaccaga tttatgatgc tatgatagag
     3181 gttccagaag taacggatac tgaggttaaa ttagtctggt atccagcctg gacagttgaa
     3241 aaaatgagtc gctatgcccg cattgcccta ggcattaagt aaacatataa aagcatgtga
     3301 gagactgttg gaaaagcgag gaaatttccc ctcttttcct ctagtctctc ctttcttttg
     3361 ctgattttat tcaaagaaaa tgatataata gtagttatgg agaaaaagaa attacgcatc
     3421 aatatgttga gttcaagtga gaaagtagca ggacaaggag tttcaggtgc ttaccgtgaa
     3481 ttagttcgtc ttcttcaccg tgctgccaag gaccaattga ttgttacaga aaatcttcca
     3541 atcgaggcag atgtgactca ctttcatacc attgattttc cctattattt atcaaccttc
     3601 caaaagaaac gctcagggag aaagattggc tatgtgcatt tcttgccagc tacacttgag
     3661 ggaagtttga aaattccatt tttcttaaag ggaattgtga aacgctatgt attttctttt
     3721 tacaaccgga tggagcactt ggttgtggtc aatcctatgt ttattgagga tttggtagca
     3781 gctggtattt cacgtgaaaa agtgagctat attcctaact ttgtcaacaa ggaaaaatgg
     3841 catcctctac cacaagaaga ggtagtcaga ctgcgcacag atcttggtct tagtgacaat
     3901 cagtttatcg tagtaggtgc tgggcaagtt cagaaacgta aagggattga tgactttatc
     3961 cgtctggctg aggaattgcc tcagattacc tttatctggg ctggtggctt ctcttttggt
     4021 ggtatgacag atggttatga acactataag aaaattatgg aaaatccccc taaaaatttg
     4081 atttttccag gcattgtatc gccagagcgg atgcgcgaat tgtatgctct agcggatctt
     4141 ttcttgttgc ctagttacaa tgagctcttt cctatgacta ttttagaagc tgcgagttgt
     4201 gaggctccta ttatgttgcg tgatttagat ctctataagg tgattttgga gggaaattat
     4261 cgggcgacag cgggtagaga agagatgaaa gaggctattt tggaatatca agcaaatcct
     4321 gttgccttaa aagatctcaa agaaaaggct aagaatattt ccagagagta ttctgaagag
     4381 catctgttac aaatctggtt ggacttttat gagaaacaag ccgctttagg gagaaagtaa
     4441 aaagtgaggt aatctatgcg aattggttta tttacagata cctattttcc tcaggtttct
     4501 ggtgttgcga ccagtattcg aaccttgaaa acagaacttg aaaagcaggg acatgctgtt
     4561 tttatcttta cgacgacaga taaggatgtc aatcgctacg aagattggca aattatccgc
     4621 attccaagtg ttcctttctt tgcttttaag gatcgtcgct ttgcctaccg aggttttagc
     4681 aaggcacttg aaattgctaa acagtatcag ctagatatta tccatactca gacagaattt
     4741 tctcttggcc tgttggggat ttggattgcg cgtgaattga aaattccagt catccatacc
     4801 tatcacaccc agtatgaaga ctatgtccat tatattgcta aggggatgtt gatccggccg
     4861 agtatggtca agtatctggt tagaggtttc ctgcatgatg tggatggggt tatttgccct
     4921 agtgagattg tccgtgactt gctatctgat tataaggtca aggttgaaaa acgggtcatt
     4981 cctactggga ttgaattagc caagtttgag cgtccggaaa tcaagcagga aaatttgaaa
     5041 gaactgcgta gtaaactagg gattcaagat ggtgaaaaga cgttgcttag tctttcgaga
     5101 atctcctatg aaaaaaatat tcaagcagtt ttagcagcct ttgctgatgt tctgaaagag
     5161 gaagacaagg ttaaactggt agtagctggg gatggccctt atctgaatga cctcaaagag
     5221 caagcccaga acctagagat tcaagactca gtcatcttta cagggatgat tgctcctagt
     5281 gagacggctc tttactataa agcggcggat ttcttcattt cggcatcgac aagcgaaacg
     5341 caaggtttga cctacttgga aagcttagcc agtggaacac ctgtcattgc tcacggaaat
     5401 ccttatttga acaacctcat cagtgataaa atgtttggaa ccttgtacta tggagaacat
     5461 gatttggctg gtgctatttt ggaagccctg attgcaacac cagacatgaa cgagcatacc
     5521 ttatcagaga aattgtatga gatttcagct gagaactttg ggaaacgagt gcatgagttt
     5581 tatctggatg ctattatttc aaataacttc cagaaagatt tggctaaaga tgatacggtc
     5641 agtcagcgta tctttaagac agttttgtat cttccgcaac aggtggttgc tgtacctgta
     5701 aaaggttcta gacgcatgtt gaaggcttca aaaacacagt tgatcagtat gagagattat
     5761 tggaaagacc atgaagaata gaaagaggaa cagtatgaaa aaacaattaa tgagaagcgg
     5821 tcgtgataaa aagattgctg gtgtttgtgc tggggtagcc cattattttg atatggatcc
     5881 tactattgtt cgcgtaatat ggggtgttct tgcttttggt tatggagcag gagttatagc
     5941 ttatatcatt ttatggatta tcgcacctgt agtaactgac tattgaaaac tagctaaatt
     6001 catgctaaga taatagaaaa tagaatgcaa cgaaggagag aaaaatggca tttggagata
     6061 atggaaatcg taaaaaaact atgtttgaga aaataacctt gtttatcgtg attatcatgc
     6121 tagtagcaag tttattggga atttttgcaa ctgcaattgg tgccctcagt aatctataaa
     6181 atagattcaa gaaaatttag tgactgggat ttcccagccc ttttttaaag tgagaagaaa
     6241 aaatgagtat gtttttagat acagctaaga tcaaggtcaa ggctggtaat ggtggtgatg
     6301 gcatggttgc ctttcgccgt gaaaaatatg tccctaatgg tggtccttgg ggtggtgatg
     6361 gtggtcgtgg aggcaatgtg gtcttcgttg tagacgaagg actacgtacc ttgatggatt
     6421 tccgctacaa tcgtcatttc aaggctgatt ctggtgaaaa agggatgacc aaagggatgc
     6481 atggtcgtgg tgctgaggac cttagagttc gagtaccaca aggtacgact gttcgtgatg
     6541 cggagactgg caaggtttta acagatttga ttgaacatgg gcaagaattt atcgttgccc
     6601 acggtggtcg tggtggacgt ggaaatattc gtttcgcgac accaaaaaat cctgcaccgg
     6661 aaatctctga aaatggagaa ccaggtcagg aacgtgagtt acaattggaa ctaaaaatct
     6721 tggcagatgt cggtttagta ggtttcccat ctgtagggaa atcaacactt ttaagtgtta
     6781 ttacctcagc taaacctaaa attggtgcct accactttac cactattgta ccaaatttag
     6841 gtatggttcg cacccaatca ggtgaatcct ttgcagtagc cgacttgcca ggtttgattg
     6901 aaggggctag tcaaggtgtt ggtttgggaa ctcagttcct ccgtcatatc gagcgtacac
     6961 gtgttatcct tcacatcatt gatatgtcag ctagcgaagg ccgtgatcca tatgaggatt
     7021 acctagctat caataaagag ctggagtctt acaatcttcg cctcatggag cgtccacaga
     7081 ttattgtagc taataagatg gacatgcctg agagtcagga aaatcttgaa gactttaaga
     7141 aaaaattggc tgaaaattat gatgaatttg aagagttacc agctatcttc ccaatttctg
     7201 gattgaccaa gcaaggtctg gcaacacttt tagatgctac agctgaattg ttagacaaga
     7261 caccagaatt tttgctctac gacgagtccg atatggaaga agaagcttac tatggatttg
     7321 acgaagaaga aaaagccttt gaaattagtc gtgatgacga tgcgacatgg gtactttctg
     7381 gtgaaaaact catgaaactc tttaatatga ccaactttga tcgtgatgaa tctgtcatga
     7441 aatttgcccg tcagcttcgt ggtatggggg gtgatgaagc ccttcgtgcg cgtggagcta
     7501 aagatgggga tttggtccgc attggtaaat ttgagtttga atttgtagac taggagactg
     7561 gtatgggaga taaaccgata tctttccgag atgcggatgg taattttgtt tccgccgcag
     7621 acgtttggaa tgaaaagaaa ttggaagaac tatttaatcg tctcaatcca aatcgtgcct
     7681 tgagattggc acgaactaaa aaggaaaatc catctcagta aagaagctaa aaaatcccgg
     7741 ctctttgtca actgtagtgg gttgaagtca gctaagctcg agaaaggaca aattttgtcc
     7801 tttctttttt gat
//
LOCUS       DAVDZK010000064         7364 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVDZK010000064 DAVDZK010000000
VERSION     DAVDZK010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.065"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..930
                     /gene="lytB"
                     /locus_tag="VUX16_002030"
     CDS             <1..930
                     /gene="lytB"
                     /locus_tag="VUX16_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET8124921.1"
                     /translation="WYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVP
                     VTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASK
                     DFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFK
                     DLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNW
                     GRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNK
                     ASGMNVEYASDPYWGEKIASVMMKINEKLGGKN"
     gene            complement(991..2646)
                     /gene="pavA"
                     /locus_tag="VUX16_002031"
     CDS             complement(991..2646)
                     /gene="pavA"
                     /locus_tag="VUX16_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET8124922.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMILRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMRKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHRVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2751..3248
                     /gene="ybeY"
                     /locus_tag="VUX16_002032"
     CDS             2751..3248
                     /gene="ybeY"
                     /locus_tag="VUX16_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET8124923.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMFEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3229..3624
                     /locus_tag="VUX16_002033"
     CDS             3229..3624
                     /locus_tag="VUX16_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET8124924.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3641..4540
                     /gene="era"
                     /locus_tag="VUX16_002034"
     CDS             3641..4540
                     /gene="era"
                     /locus_tag="VUX16_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET8124925.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKATKVPVILVVNKIDKVHPDQLLSQIDDFRNQIDFKEIVPISALQGNNMSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDCMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEKEY"
     gene            4589..5413
                     /gene="mutM"
                     /locus_tag="VUX16_002035"
     CDS             4589..5413
                     /gene="mutM"
                     /locus_tag="VUX16_002035"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET8124926.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LTSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKAGQACSRCGTVIEKFQLGGRGTHFCPNCQRRD"
     gene            5413..6018
                     /locus_tag="VUX16_002036"
     CDS             5413..6018
                     /locus_tag="VUX16_002036"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET8124927.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRKQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6005..7204
                     /locus_tag="VUX16_002037"
     CDS             6005..7204
                     /locus_tag="VUX16_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HET8124928.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVSFMSIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNETALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7204..7353
                     /gene="rpmG"
                     /locus_tag="VUX16_002038"
     CDS             7204..7353
                     /gene="rpmG"
                     /locus_tag="VUX16_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET8124929.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
BASE COUNT         2029 a         1401 c         1696 g         2238 t
ORIGIN      
        1 tggtactact tcaaatctgg tggctacatg gcgaaaaatg agacagtaga tggttatcag
       61 cttggaagcg atggtaaatg gcttggagga aaagctacaa atgaaaatgc tgcttactat
      121 caagtagtgc ctgttacagc caatgtttat gattcagatg gtgaaaagct ttcctatata
      181 tcgcaaggta gtgtcgtatg gctagataag gatagaaaaa gtgatgacaa gcgcttggct
      241 attactattt ctggtttgtc aggctatatg aaaacagaag atttacaagc gctagatgct
      301 agtaaggact ttatccctta ttatgagagt gatggccacc gtttttatca ctatgtggct
      361 cagaatgcta gtatcccagt agcttctcat ctttctgata tggaagtagg caagaaatat
      421 tattcggcag atggcctgca ttttgatggt tttaagcttg agaatccctt ccttttcaaa
      481 gatttaacag aggctacaaa ctacagtgct gaagaattgg ataaggtatt tagtttgcta
      541 aacattaata atagcctttt ggagaacaag ggcgctactt ttaaggaagc cgaagaacat
      601 taccatatca atgctcttta tctccttgcc catagtgccc tagaaagtaa ctggggaaga
      661 agtaaaattg ccaaagataa gaataatttc tttggcatta cagcctatga tacgacccct
      721 tacctttctg ctaagacatt tgatgatgtg gataagggaa ttttaggtgc aaccaagtgg
      781 attaaggaaa attatatcga taggggaaga actttccttg gaaacaaggc ttctggtatg
      841 aatgtggaat atgcttcaga cccttattgg ggcgaaaaaa ttgctagtgt gatgatgaaa
      901 atcaatgaga agctaggtgg caaaaattag tactataagt gaatatgatt tgagtgaata
      961 gtaagttaaa aatcctgatt tcaagtaaaa tcaggatttt ttcatggatg caattttttt
     1021 ggagtctggt gtgacgcgga gggtcttttg tcctgtgtaa gtgacaaagc cgggttttcc
     1081 accagttggt ttattgagtt ttttgacttc aatcatatct acctgcacca gattcgacag
     1141 gcgcccttga gagaagtagg cagctaactc tgctgcgtct gtctttactg catcagatgg
     1201 gtcaagattt cctgagatga caacatggct tccaggaatg tccttagcat ggaaccaaag
     1261 ttcctccttg cgggccattt taaaggtcaa ttcctcattt tgaagattgt ttcgtccgac
     1321 atagatgatg gttttgccat cgcttgctag atattgttct agttttttgc gtttctggat
     1381 tttctcccgt tgtcttctgc ggataaaacc tgtttgaatc aattcttcac ggatttcagc
     1441 gatttcttcc agtccagctt ggttgaggac ggtttctaca ctttccagat agagaatagt
     1501 ggctttggtt tcttcaatca aatcagtcaa gtatttgaca gcttctttga gtttctgata
     1561 ccgtttaaaa tagcgttggg cattctggtt gggagtcaga gccttatcaa gcgcaatcat
     1621 gataggttgg ttggtatagt agttgtctag gataacctga tcttggtcgt taggcactcg
     1681 gtggaggaag gttgtcagta attctccttt ttgacgaaat tcttcagcgt tgtctgtcgc
     1741 cagtaactct ttttcctgtt ttttgagttt gtgtcggttt ttctgaagtt cattttcaac
     1801 acgacgaatc agttcactgg cctgctgttt gacgcggtcg cgctcagcct tatccttata
     1861 gtaggtgtcc aacaaatcag aaagatttgc aaaaggctct cccacctgat ttgcaaaagg
     1921 aactggactg aaggaagtct cagtcaagca tggcttggtt tcttgattga aaaaatttcg
     1981 gaaagcggaa agtttttcac taaccagtat cctttccaat tcatttgccg tatcgcgtcc
     2041 cagaccttga aagaggcttt gaagattttt tgctgttagt tcttgggttt gcaggatttc
     2101 aaagagcttt tcatccttga tagtaaaagg attgagagat tctgtacttg gcggagcgat
     2161 ataggtcgat cctggaagta aggtgcggta gctattttgt gaaaagccga cgtgtttgat
     2221 aacttcgagg attttatgac tgcttttatc gaccagtaga atattactgt gtttcctcat
     2281 aatttcgata atcaaggtag cctggatatg gtctccaatc tcgtttttat tggaaactgt
     2341 aatttccaca atacggtcat tttccacttg ctcaatcgac tcaatcaggg ccccctgcaa
     2401 atactttctc aaaatcatga taaaggtaga aggttgggct ggattttcaa aagtcgtttg
     2461 ggtcagctga atgcgtccaa aaactggatg ggcagaaagg agcaggcgat ggctttggcg
     2521 attgctgcgg atttgcaaga ccaactcttg ttcaaaaggc tgattgattt tctggatgcg
     2581 accattcact aattcgcttc gcaattcctc aactatgtgg tgtaaaaaaa atccgtcaaa
     2641 tgacatcgtt ctctccttgt gattgtattc catagtatta tatcaaaaag gtagaataaa
     2701 atcatggaaa tgtggtataa taaagccaag taaagagaaa cgagaagcac atgtatattg
     2761 aaatggtaga tgaaactggt caagtttcaa aagaaatgtt gcaacaaacc caagaaattt
     2821 tggaatttgc agcccaaaaa ttaggaaaag aagacaagga gatggcagtc acttttgtga
     2881 ccaatgagcg tagtcatgaa cttaatctgg agtaccgtga caccgaccgt ccgacagatg
     2941 tcatcagcct tgagtataaa ccagaattgg aaattgcctt tgacgaagag gatttgcttg
     3001 aaaatccaga attggcagag atgatgtttg agtttgatgc ctatattggg gaattgttca
     3061 tctctatcga taaggctcat gagcaggccg aagaatatgg tcacagcttt gagcgtgaga
     3121 tgggcttctt ggcagtacac ggctttttac atattaacgg ctatgatcac tacactccgg
     3181 aagaagaagc ggagatgttc ggtttacaag aagaaatttt gacagcctat ggactcacaa
     3241 gacaataaac gaaaatggaa aaatcgtgac ttgatatcca gtttagaatt tgctttgaca
     3301 ggtattttta ctgctatcaa ggaagaacgc aatatgcgaa aacacgcagt gacggctcta
     3361 gtggtcatcc ttgcaggttt tgtttttcag gtgtcacgaa tcgaatggct ctttctccta
     3421 ttgagcattt tcttggtagt agcctttgag attatcaact ctgctattga aaatgtggtg
     3481 gatttggcca gtcactatca cttttccatg ctggctaaaa atgccaagga tatggcggct
     3541 ggcgcggtat tagtggtttc tcttttcgca gccttaacag gcgcattgat ttttctccca
     3601 cgaatctggg atttattatt ttaaacagta agaggaaatt atgactttta aatcaggctt
     3661 tgtagccatt ttaggacgtc ccaatgttgg gaagtcaacc tttttaaatc acgttatggg
     3721 gcaaaagatt gccatcatga gtgacaaggc gcagacaacg cgcaataaaa tcatgggaat
     3781 ttacacgact gataaggagc aaattgtctt tatcgacaca ccagggattc acaagcctaa
     3841 aacagctctc ggagatttca tggttgagtc tgcctacagt acccttcgcg aagtggacac
     3901 cgttcttttc atggtgcctg ctgatgaagc gcgtggtaag ggggacgata tgattatcga
     3961 gcgtctcaag gctaccaagg ttcctgtgat tttggtggtg aataaaatcg ataaggtcca
     4021 tccagaccag ctcttgtctc agattgatga cttccgtaat caaatagact ttaaggaaat
     4081 tgttccaatc tcagcccttc agggaaataa tatgtctcgt ctagtggata ttttgagtga
     4141 aaatctggat gaaggtttcc aatatttccc gtctgatcaa atcacagatc atccagaacg
     4201 tttcttagtt tcagaaatgg ttcgcgagaa agtcttgcac ctaactcgtg aagagattcc
     4261 gcattctgta gcagtagttg ttgactgtat gaaacgagac gaagagacag acaaggttca
     4321 catccgtgca accatcatgg tcgagcgcga tagccaaaaa gggattatca tcggtaaagg
     4381 tggcgctatg cttaagaaaa tcggtagtat ggcccgtcgt gatatcgaac tcatgctagg
     4441 agacaaggtc ttcctagaaa cctgggtcaa ggtcaagaaa aactggcgcg ataaaaagct
     4501 agatttggct gactttggct ataatgaaaa agaatactaa gtagaggtgg gctcatgcct
     4561 gcttcttgtt tttacagaag gaggacttat gcctgaatta cctgaggttg aaaccgtttg
     4621 tcgtggctta gaaaaattga ttataggaaa gaagatttcg agtatagaaa ttcgctaccc
     4681 caagatgatt aagacggatt tggaagagtt tcaaagggaa ttgactagtc agattatcga
     4741 gtcaatggga cgtcgtggaa aatatttgct tttttatctg acagacaagg tcttgatttc
     4801 ccatttgcgg atggagggca agtattttta ctatccagac caaggacctg aacgcaagca
     4861 tgcccatgtt ttctttcatt ttgaagatgg tggcacgctt gtttatgagg atgttcgcaa
     4921 gtttggaacc atggaactct tggtgcctga ccttttagac gcctacttta tttctaaaaa
     4981 attaggtcct gaaccaagcg aacaagactt tgatttacag gtctttcaat ctgcccttgc
     5041 caagtccaaa aagcctatca aatcccatct cctcgaccag accttggtag ctggacttgg
     5101 caatatctat gtggatgagg ttctctggcg agctcaggtt catccagcta gaccttccca
     5161 gactttgaca gcagaagaag cgacagctat tcatgaccaa accattgctg ttttgagcca
     5221 ggctgttgaa aaaggcggtt ccaccattcg gacctatacc aatgcctttg gggaagatgg
     5281 aagcatgcag gactttcatc aggtctatga caaggctggt caagcatgtt cacgctgtgg
     5341 gacagtgatt gagaaattcc agctcggtgg acgtggaacc cacttttgtc caaactgtca
     5401 aaggagggac tgatgggaaa aatcatcgga atcactgggg gaattgcctc tggtaagtca
     5461 actgtgacaa attttctaag aaagcaaggc tttcaagtag tggatgccga cgcagtcgtc
     5521 caccaactac agaaacctgg tggtcgtctg tttgaggctc tagtacagca ctttgggcaa
     5581 gaaatcattc ttgaaaacgg agaactcaat cgccctctcc tagctagtct catcttttca
     5641 aatcctgaag agcaaaaatg gtcgaagcaa attcaagggg agattatccg tgaggaactg
     5701 gctactttga gagaacagtt ggctcagaca gaagagattt tcttcatgga tattccccta
     5761 ctttttgagc aagactacag cgattggttt gctgagactt ggttggtcta tgtggaccga
     5821 gatgcccaag tagaacgctt aatgaaaagg gaccagttgt ccaaagatga agctgagtct
     5881 cgtctggcag cccagtggcc tttagaaaaa aagaaagatt tggccagcca ggttcttgat
     5941 aataatggca atcagaacca gcttcttaat caagtgcata tccttcttga gggaggtagg
     6001 caagatgaca gagattaact ggaaggataa tctgcgtatt gcctggtttg gtaattttct
     6061 gacaggagcc agtatttctt tggttgtatc ttttatgtcc atcttcgtgg aaaatctagg
     6121 tgtagggagt cagcaagtcg ctttttatgc aggcttagca atttctgtct ctgctatttc
     6181 cgcggcgctc ttttctccta tttggggtat tcttgctgac aaatacggcc gaaaacccat
     6241 gatgattcgg gcaggtcttg ctatgactat cactatggga ggcttggcct ttgtcccaaa
     6301 tatctattgg ttaatctttc ttcgtttact aaacggtgta tttgcaggtt ttgttcctaa
     6361 tgaaacggca ctgatagcca gtcaggttcc aaaggagaaa tcaggctctg ccttaggtac
     6421 tttgtctaca ggcgtagttg caggtactct aactggtccc tttattggtg gctttatcgc
     6481 agaattattt ggcattcgta cagttttctt actggttggt agttttctat ttttagctgc
     6541 tattttgact atttgcttta tcaaggaaga ttttcaacca gtagccaagg aaaaggctat
     6601 tccaacaaag gaattattta cctcggttaa atatccctat cttttgctca atctcttttt
     6661 aaccagtttt gtcatccaat tttcagctca atcgatcggc cctattttgg ctctttatgt
     6721 acgcgactta gggcagacag agaatcttct ttttgtctct ggtttgattg tgtccagtat
     6781 gggcttttcc agtatgatga gtgcaggagt catgggcaag ctaggtgaca aggtgggcaa
     6841 tcatcgtctc ttggttgtcg cccagtttta ttcagtcatc atctatctcc tctgtgccaa
     6901 tgcctctagc ccccttcaac taggactcta tcgtttcctc tttggcttgg gaaccggtgc
     6961 cttgattccc ggggttaatg ccctactcag caaaatgact cccaaagccg gcatttcgag
     7021 ggtctttgcc ttcaatcagg tattctttta tctgggaggt gttgttggtc ccatggcagg
     7081 ttctgcagta gcaggtcaat ttggctacca tgctgtcttt tatgcgacga gcctttgtgt
     7141 tgcctttagt tgtctcttta acctgattca atttcgaaca ttattaaaag taaaggaaat
     7201 ctagtgcgag taaaaatcaa tctcaaatgc tcctcttgtg gcagtatcaa ttacctaacc
     7261 agtaaaaatt caaaaaccca tccagacaag attgaggttt taaagtattg tcccaaggaa
     7321 agaaaagtaa ccctacatct tgaatctaag tagattttat ggta
//
LOCUS       DAVDZK010000065         7219 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVDZK010000065 DAVDZK010000000
VERSION     DAVDZK010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7219
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.066"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            703..1824
                     /gene="mnmA"
                     /locus_tag="VUX16_002039"
     CDS             703..1824
                     /gene="mnmA"
                     /locus_tag="VUX16_002039"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET8124930.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVIAVADQISIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLNQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLATAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVAGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFMREMPEEFTLECTAKFRYRQPDSKVTVHVKGEKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1965..2420
                     /locus_tag="VUX16_002040"
     CDS             1965..2420
                     /locus_tag="VUX16_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET8124931.1"
                     /translation="MTQQDFRTKVENTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEGAVVREVREELGVKAQAGQLAFVVENHFEQDGVYYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTTLPDWDGQLKHIHREE"
     gene            2430..4343
                     /gene="mnmG"
                     /locus_tag="VUX16_002041"
     CDS             2430..4343
                     /gene="mnmG"
                     /locus_tag="VUX16_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET8124932.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEAMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPVNIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4550..4642)
                     /locus_tag="VUX16_002042"
                     /pseudo
     CDS             complement(4550..4642)
                     /locus_tag="VUX16_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4696..6375)
                     /locus_tag="VUX16_002043"
     CDS             complement(4696..6375)
                     /locus_tag="VUX16_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET8124933.1"
                     /translation="MAYTLKPKEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKTP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6377..6610)
                     /locus_tag="VUX16_002044"
     CDS             complement(6377..6610)
                     /locus_tag="VUX16_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET8124934.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRIAARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
BASE COUNT         2034 a         1456 c         1689 g         2040 t
ORIGIN      
        1 gctatagagt caatgccaat ggtgaatggg tttaagccga ttcaattaaa tcatgttaag
       61 aacatttgac attttaattt tgaaacaaag ataaggttcg attgaataga tttatgttcg
      121 tattctttag gtacctatct tatgatttca ggaagtgtca ttaaaaaaac gactcctttt
      181 ctctaacttg aaaaatagat tagagaaaat gggttgtttt atttattata gttatttgaa
      241 tgaaaataag aagaaggtat actcacgtca ttcacatgat ctgtatattg actataagtt
      301 ttaaaaaaca atttttaagc tctttcttgt cttctctaac caagcgtgtt ataatgaata
      361 ctgctcaagc gaccttcaat cgttaagcac acacgacctt caatcgtgaa ctagtcattt
      421 cgtttatctt ttattacgtc gttaactcga aataagatgc aagctgagct tgtctgattt
      481 ataacctcaa tcagtctccc agactgattg agcgaactca agttatgcct gcgactcgtt
      541 gcctatcata ttttcatttt aagatgatag gctaaaatgg tcttccagac cattttacta
      601 ctaaaagcaa acgaaatgac tatactcaaa taaattctat tgaaagtcat agtaaataga
      661 attttgaggg gtataaataa acgaatagat gggagactta ccatgagtga taactctaaa
      721 acacgtgttg ttgtggggat gagtggtggt gttgattcgt cggtgacggc tcttttgctc
      781 aaggagcagg gctacgatgt gatcggtatc ttcatgaaga actgggatga cacagatgaa
      841 aacggcgttt gcacggcgac cgaagattac aaggatgtga ttgcggtggc agaccagatt
      901 agcattccct actactctgt caattttgaa aaagagtact gggaccgcgt ttttgagtat
      961 ttcctagcgg aataccgtgc agggcgcacg ccaaatccgg acgttatgtg caacaaggaa
     1021 atcaagttca aggccttttt ggactatgcc atgaccttgg gggcagacta tgtagcgact
     1081 gggcattatg ctcgagtggc gcgtgatgag gacggcactg ttcacatgct tcgtggcgtg
     1141 gacaatggca aggaccagac ctatttcctc aaccaacttt cgcaagaaca actccaaaaa
     1201 accatgttcc ctttgggaca tttggaaaag cctgaagtac gcagactagc agaagaagca
     1261 ggcctggcga ctgctaagaa gaaagattcg acagggattt gttttatcgg agaaaagaac
     1321 tttaaaaact tcctcagcaa ctacctgcca gctcagcctg gtcgcatgat gactgtggct
     1381 ggtcgcgata tgggcgagca tgcaggtctt atgtactata caatcggtca gcgtggcgga
     1441 ctcggtatcg gtgggcagca cggcggtgac aatgcccctt ggttcgttgt cggaaaagat
     1501 ctaagcaaga atattctcta tgtaggacaa ggattctacc atgattcgct catgtcaact
     1561 agcctagaag ccagtcaagt ccattttatg cgtgaaatgc cagaagagtt tacgctagaa
     1621 tgtacggcta aattccgtta ccgtcagcct gattctaagg tgacagtaca tgtcaaagga
     1681 gaaaaggcag aggtcatctt tgcggaacca caacgcgcga ttacaccagg acaggcagtt
     1741 gtcttttacg atggcgaaga gtgtctaggt ggcggtttga ttgacaatgc ttaccgcgat
     1801 ggacaagttt gtcagtacat ttagattgac aaattttctc aatttgctac aataataaca
     1861 gcaatagaaa tgatggtcaa agctcatgga tgttgcaggc ttttttgtcc tgcacttctt
     1921 tgtagttttg actgtttttg tgtcgtttaa gggaaaggat aaaaatgact caacaagact
     1981 ttcggacaaa agtagaaaat acggtttttg gtgttcgggc gacagccttg attgtccaaa
     2041 atcacaagct tctagttacc aaagacaagg gcaagtatta cactattggc ggtgcgattc
     2101 aagtcaatga aagcacggaa ggcgcggtag tccgtgaagt tagggaagaa ctgggtgtca
     2161 aagctcaagc tggccagcta gcttttgtag ttgaaaatca ttttgaacaa gacggtgtct
     2221 attatcacaa tatcgagttt cattatctgg tagacttact tgaagatgcc ccattgacca
     2281 tgcaggaaga tgagaaaagg cagccctgtg agtggattga cttggataag cttgaggata
     2341 tccagctagt tccagccttt ttaaaaacaa ccctacccga ttgggacggc caactaaaac
     2401 acattcatcg tgaggaatag gagagaaaca tgacttatca ttttactgaa gaatacgata
     2461 ttattgtaat tggtgcggga cacgctgggg ttgaggcttc cttagctgct agccgtatgg
     2521 gctgcaaggt cttgcttgcg accatcaata ttgaaatgct ggctttcatg ccttgtaatc
     2581 cctctatcgg tggttctgct aaggggattg tcgtacgtga agtcgatgcc ctcggtggcg
     2641 agatggccaa gaccattgac aagacttaca tccagatgaa gatgctcaac acagggaagg
     2701 gaccagccgt tcgtgccctt cgtgcgcagg ctgataagga actttactct aaggaaatgc
     2761 gcaagacagt tgaaaatcaa gaaaatctga cccttcgtca aaccatgatt gatgagattt
     2821 tggtggaaga tggcaaggtt gtcggtgtgc gtacagccac ccatcaagaa tatgctgcta
     2881 aggctgttat tgtgacgaca gggactgctc tccgtgggga aattatcatc ggagacctca
     2941 agtactcatc aggtcctaac cacagcttgg cttctattaa cctagctgac aatctcaagg
     3001 aactgggtct cgaaatcggt cgtttcaaga caggaacccc tccacgtgtc aaggcctctt
     3061 ctatcaacta cgacgtgaca gaaatccaac caggagatga agcgcctaat cacttctcat
     3121 acacttcacg tgatgaggat tatgtcaagg accaagtgcc atgctggttg acctatacca
     3181 atggtaccag tcatgagatt atccaaaaca acctccaccg tgcgcctatg tttacaggtg
     3241 tggtcaaggg agtgggacct cgttactgtc cgtcgattga agacaagatt gtgcgctttg
     3301 cggacaagga acgtcaccaa ctcttccttg agccagaagg acgtaataca gaggaagtct
     3361 atgtgcaagg actttcaacc agtctgcctg aggatgtcca gcgtgacttg gttcattcca
     3421 tcaaaggttt ggaaaatgca gagatgatgc ggacaggtta tgctattgag tatgatatgg
     3481 tcttacctca tcagttgcgt gcgactttgg aaaccaagaa aatctcaggt ctcttcactg
     3541 ctggtcagac aaatggaacg tcaggttacg aagaggcagc aggccaaggg attatcgcgg
     3601 gtatcaatgc ggctctgaaa atccaaggca agcctgagtt gattttgaag cgcagtgatg
     3661 gttatatagg ggtgatgatt gatgacttgg tgaccaaggg aaccattgaa ccctaccgtc
     3721 tcttgaccag tcgtgctgaa taccgtctca ttcttcgtca tgacaatgct gatatgcgct
     3781 tgactgagat tggccgcgag attggccttg tagacgatga acgctgggct cgttttgaaa
     3841 tcaagaaaaa tcaatttgat aatgagatga aacgcctaga cagtatcaaa ctcaagccag
     3901 tcaaggaaac caatgccaag gttgaagcga tgggattcaa accgttgaca gatgcagtga
     3961 cagccaagga attccttcgc cgtccagaag tttcttacca agatgtggta gccttcatcg
     4021 gaccagctgc agaggatttg gatgataaga ttatcgaatt gattgaaaca gaaatcaagt
     4081 acgaaggcta tatttcaaaa gccatggatc aggtagccaa gatgaaacgt atggaagaga
     4141 aacgcattcc agtcaatatc gactgggatg acattgactc tatcgcaacc gaagcccgtc
     4201 agaagttcaa actcatcaat ccagaaacca tcggccaagc cagccgtatt tcgggagtaa
     4261 acccagcaga tatttctatt ttgatggtgt atctggaagg taaaaatcgt agtatttcta
     4321 aaactcttca aaaatcaaaa tgatacgtcg tcggcttctt acgaatgagt tcaaagcttg
     4381 gctttgattc atctccagcc tcccatagtt ccccgaacta tgggagctaa ctcaagttat
     4441 gctttcgctt agccttctag tctgatttcg atttttattg atactcttcg aaaatctctt
     4501 caaaccgcgt caacgtcgcc ttgccgtagg tatggctact gacttcgtca gttctatcta
     4561 caacctcaaa gcagtgcttt gagcaaccta cggctagctt cctagtttgc tctttgattt
     4621 tcattgagta tgagttttaa tctcaaaaga aagcatagag aaaaacagct ccgaggacgg
     4681 ggctgttttc ttgctttatt cttcatctgg tgtgaggatc atcgggatga tgatcggttc
     4741 acgttcggta ttttcataga ggaaggggcg aatagcgttg acaatggcac cattgacaga
     4801 ttgcacgcta gcatccttat ttttcagtgc gatacgaatg gcattgaaga ggatacgctg
     4861 gctttggcga atcaagtcgc cagactctct catgtagaca aagcctcggc tgaggatgtc
     4921 tggaccagat agaatcatct gcgatttgaa gtcaacagtt gcgactgcca gaacgacacc
     4981 gtcttcagat agatcgcgac gatctttgag gacagctgcg ccaatttcac cgatacgatt
     5041 tccatcgaca tagatatctt gggcgttgaa atgacctgcg atacgagctg agtcagcagt
     5101 aagggcaagc acatcgccat tgctcatgat aaagatattg tccttctcaa caccagtatc
     5161 cactgctagt ccagcgtgga ctttttgcat gcggtattca ccgtggacag gcatgaagta
     5221 ttttggctta atcaagcaga gcatgagttt ttgctcttgc tgaccaccgt gtccagatgt
     5281 atggatattg ttcactttac cgtggataac ttcgacacca gcttcagaaa tgatgttaat
     5341 cagcttgttg acgctagtag tgtttccagg gatgggacta gaagagaaga taacggtatc
     5401 acctggttgt aattgtactt gacggtgggt tccgttggcg atacgagaga gggctgccat
     5461 aggctcaccc tgactacctg tacagaggat aagaacttct cctgcaggat aatctttgat
     5521 ttcatttggc tcgataaagg ttcccttagg agttttgatg tagccaagat cgattccgtt
     5581 gacaatggcc ttttccatag aacgaccaaa gaccgcaatc ttgcgtccag tcttaacagc
     5641 agcttctgtt gcctgctgga gacggaagat atttgaggca aaggatgcaa agatgatacg
     5701 tccttcaata ccttggataa tcttcataat ggactgacca acgacttttt cagagttggt
     5761 aaaggttggt acttccgcat ttgtcgagtc agacaggaga cagagcacgc cttcttcacc
     5821 aagcgcagcc atacgatgca agtccgcagg ttctccaact ggagtaaagt cgaacttaaa
     5881 gtcacccgta cagacgattt tcccttgagg agtatgaatg acaatcccca aaggctctgg
     5941 aatagagtga gtcgttctaa agaaagttgc cttgagattt ttaaaggtca actcggtgtt
     6001 gtggttgatt tcgtaaagtt tggcgttgcg caagaggccg tgttcttcga gtttcccacg
     6061 gatcaaagcc aaggcaagcg gtccagcata aatagggaca tttgcttgct tgagtaggaa
     6121 cggaatccca ccaatgtggt cctcgtgtcc gtgtgtgatt aaaacagcct tgacgcggtc
     6181 gatattgtcc acgatgtaag agtagtcagg aatgacatag tcgataccaa gcaagtcatc
     6241 ttctgggaat ttaatcccag catcgacgat gataatctcg tcttggtatt caattccgta
     6301 agtgtttttc ccgatttctc ctagaccacc gatggcaaaa acgccgactt ctttaggttt
     6361 aagagtgtaa gccatattag aactccgtaa tttcgaaggc gccagtttct ttttcgtaat
     6421 cgagcaattt gtcagacaag agttcgatat attcgatatt gtactctggg cgattttctt
     6481 cgacaagttg gcgagcagcg atacggccct caagttctga gctggcatcg atgtctaggt
     6541 aaagcgcgcg tgttgtttcg cgacgtgggc tacgttcttt tgtttcttga taaaaaactt
     6601 tgtaaatcat atagttcctt tctatttaca ggtcagctta ttccaaactt ttagcagaga
     6661 attgcttgat ttcattccat tttttgtcta gattgacctt gattcgttac aattatttca
     6721 attataccac aaaatgaaaa attagtaaaa gacggaaacg agaaagttag gggacgattt
     6781 cttcggtaag cgtttgcaaa aataaagaaa atgtgttatg ttgataacgg aagtgaagtt
     6841 tattacttgt cataattcca tatagatttt aagtcaagga ggttgtccta tgtataactt
     6901 atttgctttt gctattggag ttcgtttgct agcttttatc gtttttgttg cttgcgttta
     6961 tggaggaaat cttctatttg ctaaactgga acgatgataa accaagttct tgtggaaaat
     7021 tacctttgtg actctctact cgctttttct cctcctcatg acctatgtcg tttggtttgt
     7081 attttacttt ggattaaatg cttagatgcc ctgcatatgt gaactgcacc ccaaaagtta
     7141 gacagaaaaa atctaacttt tggggtgttt tattatgaaa ttgagttatg aagataaagt
     7201 tcagatctat gaactaaga
//
LOCUS       DAVDZK010000066         7099 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVDZK010000066 DAVDZK010000000
VERSION     DAVDZK010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7099
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.067"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(82..273)
                     /locus_tag="VUX16_002045"
     CDS             complement(82..273)
                     /locus_tag="VUX16_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET8124935.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(434..1108)
                     /locus_tag="VUX16_002046"
     CDS             complement(434..1108)
                     /locus_tag="VUX16_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124936.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(1114..1560)
                     /locus_tag="VUX16_002047"
     CDS             complement(1114..1560)
                     /locus_tag="VUX16_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET8124937.1"
                     /translation="MKLRIEIDGNLEETEIVIRTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRFKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(1674..2177)
                     /locus_tag="VUX16_002048"
     CDS             complement(1674..2177)
                     /locus_tag="VUX16_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET8124938.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLDQQVGVYVFIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(2174..2536)
                     /locus_tag="VUX16_002049"
     CDS             complement(2174..2536)
                     /locus_tag="VUX16_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HET8124939.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKVESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGIRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(2602..4461)
                     /locus_tag="VUX16_002050"
                     /pseudo
     CDS             complement(2602..4461)
                     /locus_tag="VUX16_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(4500..4949)
                     /locus_tag="VUX16_002051"
     CDS             complement(4500..4949)
                     /locus_tag="VUX16_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET8124940.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQAVRFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRMVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(5073..5789)
                     /locus_tag="VUX16_002052"
     CDS             complement(5073..5789)
                     /locus_tag="VUX16_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET8124941.1"
                     /translation="MGRKWSNIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(6670..>7099)
                     /gene="ply"
                     /locus_tag="VUX16_002053"
     CDS             complement(6670..>7099)
                     /gene="ply"
                     /locus_tag="VUX16_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET8124942.1"
                     /translation="SYTTSFLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVA
                     QYYITWDELSYDHQGKEVLTAKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGL
                     AWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKIEND"
BASE COUNT         2170 a         1620 c         1260 g         2049 t
ORIGIN      
        1 ccaggcacct aagttgccaa cgtagtaacc atcaggtgtg taggtattgc gaagcatctt
       61 acctgatgaa gccagataat actacttgcc attgtctttg acccaatcat tcgcaatcat
      121 ggaaccagaa gaacttacat aataccattc tcccttgtca taaacccaag tactgacttt
      181 catggttcct gagcaattaa aggcaaaaaa actgtccaat atcattcgtt ttttaaaagc
      241 atttgacact acatcatcta cgctgtagta catagataca tcaaacgtaa aagccaaaat
      301 atcgaaaaat atacaacttt taaaggcagc atttcatttt ttaaagtcta acaaccatag
      361 aactgaaatc agagcaaggc atcaatttcc tactcttagt acgtctattt tgatggttga
      421 agtgaagatt tttttattta acgtagacaa tttccaactt cccaaaagcc acatctccac
      481 ggatagtcaa ggttttgctg gttggggcta caggagcgtc agccttagct gcaccaaagg
      541 aggtttctac tttcaaatct acacgccagt gttgtggaac atagacggtt gcatttccga
      601 aggccacttc aatatttaaa gttgcaaaat cacctagcat ctctgcatta tcatagtaga
      661 ttttagcatc cccaaaagcg acttccactt ggtcatctac gagatcttga tcttgcttat
      721 agaaggtccc gctaccaaaa gcgacttcct tatccgtgac gactgttttt ttcccattgt
      781 accaccattt tttttcattc cagaacttac ttgaatgcgt cagataacca acaccaagta
      841 ccaccaagat gctagcccaa ataagagaat gattggtaac tggtaacaag tcataagcgt
      901 aatttgcaat gatgagcgcc agtaaacctg taaaaactgc cgaagtgaga tgacgtctaa
      961 ggatggactc aatggactta taagcaaaaa aaacaatacc tagtaaaggc catattttac
     1021 catccaaaga aggaattcca aaattccctt gcagcaagat ccaagctgct aaaaccaata
     1081 aaacaatacc aaatgctttc tttttcatgt tttttacctc atgtttctta gattttcttt
     1141 taggagggat tggtaatgcc gtgagacatg aacctccttg tgcgtctgat agaaggaaat
     1201 ggtgcccgtt cctgaaaagg acttgtccac tgagtaaatc tgacggatgt ttgcgatcgt
     1261 tgacttggaa actcgattaa aatagcgagg caagatagat tccaactcat agagcttgaa
     1321 gcgaacctca taagcttcct tctggttatg agcgtagatc ttgctccctt ctgtttcaaa
     1381 gaagagaatt tctgacaggt ctagataata ttcacctgtc cccttgtaaa aagtcaacct
     1441 cggagccttt gactcttgca agagccgttg caagtctgca atttcatctg tcaaagtggg
     1501 ggtcctgatg acaatttcag tctcctctaa attaccgtca atctcaattc gtaacttcat
     1561 cacatctcct ttctgactct actatatcaa agctaagtta ggaatacaag ggcaaaaaag
     1621 caagtggtca atttgaagca gtaagtggtt gtaggactag cttaacttac atgtcagaat
     1681 aggaagaaaa ggaatcccca caccagacca caagcatagc caaccaagac atccttggga
     1741 taatgaacac cccctaaaac cctcaccaac cccagcaaag ctgaaaagat caagcatact
     1801 aagccaatag gtagactagc atgcagacag gccatggaga tgatagttgc cgaaaagaca
     1861 tggcgactgg gcatcgaccg tcccgaacta tccttatcaa gaaggggaca gatatcccaa
     1921 gtttcataag gtctcgggtg attgattttc ttacgaaaca gggacaaggc cacaaaacct
     1981 gatgcaggaa taaacacata aaccccaact tgctgatcaa gtcctagttg caggtaagtg
     2041 gtgactagca agatcagata gaccaggggc atggcgactg tcatcaaacg attgaaactg
     2101 cgtaatagga ataaaagaat tggacgacta gttagtctgg agctgatatt tcgataccat
     2161 tcttgataat ttttcattta tgcttctcat acttttctag aacttgttga gatgttttcc
     2221 ccttggcaag ccaatccact agcttgtcca agcgacgtat ttcctgcatc agaggatcat
     2281 caatttcctc aatacggata ccgcaaatct tccctgtaat tgcaattcgt tcagggacat
     2341 aatatggtgc ttgtcgaaaa aaatctccgt aagtaacatc cctatccaga caagcaagaa
     2401 cgtcactcac ttcataccct gtcaaccaac tggtcacttg gtgaactgac tctacctttc
     2461 caccctttcg ctcaactttt gcaatcaagg ctaagtagac agcagcaaat ttcatattgt
     2521 ataatttctg actcatactt ctctctttct atgtgtacta gtataaatca gaaaaagaag
     2581 gccgtcaagc cttcttttga tttattcttc tgcttcatct tctgtaaatt gactattgta
     2641 caagtcagcg tagaagccac cttgcgccat cagttcctca tagttgcctt gctcgatgat
     2701 atttccatct ttcatgacca agatcaaatc tgcattttgg atggttgaca agcggtgggc
     2761 aatgacaaag gatgtgcgtc cttccatcaa acggtccatg gctttttgga tcaattcctc
     2821 tgtccgtgtg tcaacagaag aagtcgcctc atccaaaatc aaaagcggtc catccttaag
     2881 aagggcacga gcaatagtca atagttgttt ttgtcctaca gacaaggtca cggtgtcatc
     2941 caagatggta tcatagccat ctggcaaggt cataataaag tggtgaattc ccacagcctt
     3001 actagcttcc atcattcgtt catcactaat ccctatttga ttatagatga gattgtcccg
     3061 aatagttcct tcaaagagcc aggtatcctg caagaccatt gaaaaagcat catgcacttc
     3121 tgaacgcgtc atagccttgg tatccacacc atcaatgcga atacttccct tatcaatctc
     3181 atagaatttc atcaaaagat tgacaatggt tgtcttacca gccccagtcg gcccaacaat
     3241 ggcaaccttt tgaccagcat gagctgtcgc agagaagtca tagtcttgaa cattgacacc
     3301 gtccaccaga atttctcctg ctgacacgtc gtagaaacgt ggaatcagat tgaccagagt
     3361 tgatttacca gaacctgttg acccaataaa ggccactgtt tgaccagttt ctgctttaaa
     3421 gctaacatgt tcaataactg cctccgaatt tgccgcatag cggaaggtca catccttaaa
     3481 ctcgacctga cctttgaagt tttcatcagc cagctgcact tgaacagagt tttggataga
     3541 agaatgcaaa tctaaaactt gattaatccg cttagcagag accatagttc ggggaagaac
     3601 gatgaagagt gctcccatga gaaggaagcc catgacaacc tacatggcat aagacatgaa
     3661 aacaatcatg tcactaaaga gaggcagacg cgctatcgga gcaacgtcgt taatcacata
     3721 ggccccaatc cagtaaatcg ctacactcaa accacttgaa atccccatca tgataggatt
     3781 caaaatagcc ataagacggt tgacaaacaa attcaaacgg gtcaattcat catttactgc
     3841 tgcaaatttt tcattttgat aatcctctgc attgtagaca cgaacgacac gaatacctgt
     3901 taaactctca cgagtgatac tgttcagttt atctgtcagc ccctgaatca aggactgttt
     3961 tgaaaaggct agcgtcatca aaacggtcgt catcaggacg ttgacaatca ctgccacaag
     4021 tacggcccag agtcagtatt ctgaatgacc taaaatcttc ccaatagccc agatagccat
     4081 aattgaacca cgcgttacca cttgcaagcc catagtaatc aacatttgaa cttgagtaat
     4141 gtcattggta gtacgcgtca agaggctagg aattgaaaat ttcttaatct ttgtctgcga
     4201 gtaatccaaa actcggttaa aaatatcact tctcagccta ctaatataag aagccgccac
     4261 tcgggatgca aaaaatccaa ctgcaactac ggacaagaag gcaagaaagg gcattcccat
     4321 catcatgctt gccggctgcc acaactcatc taaattagtt ccttgactac ctagcaaatc
     4381 cgtaattttc gagatatagg tcggcacttc caactctaga tagaccgaaa agcaagtaaa
     4441 gagaatggct agtaaaatca tcccccattc ttttctacta attcttttgg ctaatttctt
     4501 tattctctcc tcctattccc ttgatatttt gcctgtagtt gaccgagaac tttctcaaaa
     4561 atcagtaatt catcttcatc aatgtcttcc atcaactgct tgtctatgcg ttcaaaaaaa
     4621 gccttaacct gttgcatctg agaacgtgct ttgtccgtca gacgaacaaa cttagcccgc
     4681 ttatcaacag gactcgcctc caattccacc aaaccatttt gcaccatacg cttaaccaga
     4741 ttactagcaa cagacttggt aatattgagt tcctgctcga tatctttaat caagaccaag
     4801 tcttggtttt tctcgcgatt atccaaaaaa cgcacagcct gaccttgcgg cccacccata
     4861 aattcaatgc cgcaacgttt ggcttccttt tgcaccatca ggtgaatttg atgaccaaaa
     4921 cgcttaaaga ctaacatcgg tttatccata atctccccct tctaaataaa aatagttctc
     4981 tggagaataa ttaaatttct atgagaacta ttttcttgat taaaaaaatc ccaagtgatt
     5041 ttctcactta ggatcatgtt ctataggtta aattaaaacc catctacgtt cgtataaatc
     5101 ttttggacgt cttcgtcgtc ttcaagaacg ctgtaaagtt tttcaaaggt ttcaaggtct
     5161 tcgcctgaca attccacttc tgactgagga atcatttcca attcagtcac ttggaattct
     5221 tcaataccag actcacggag ggcaacgata gccttgtgaa ggtcagttgg cgctgtgtaa
     5281 actgtgattg taccttcttg tgcttctacg tcatccacat ccacatccgc ttcgagcaat
     5341 tgctcaaaga ctgcgtccgc atcttcacct ccaaatacaa taacaccttt gttgtcaaag
     5401 aggtaagaaa cagaacctga agcgcccatg tttccgccgt ttttaccaaa ggctgcacgg
     5461 acattggctg ctgtacggtt aacgttagaa gtcaaagtat ccacaattag catagagcca
     5521 tttggcccaa aaccttcgta acgtccttct gtaaaggttt cgtctgtgtt tcctttggct
     5581 ttatcaatcg ctttatcgat aacgtgtttt ggcacttggg cttgtttagc acggtcgata
     5641 acgaatttca aagctgagtt tgattctgga tctggatcac cttttttagc tgctacatag
     5701 atttctacac caaattttgc atatacttta gagttggctc catctttagc cgttttcttg
     5761 gctacgatat tggaccattt acgtcccatt aggaatctcc ttttttcaca ttttaatctt
     5821 tcttattata acacaagttt ttttgatttt cactagagga aatgggtttt attagcaaat
     5881 caagctagga tagtacttta cctgctaaga tggtcttgcc tttctatctt tatcaacaga
     5941 cactcatcca cattcaaaaa acaaactaga ccattatctg caaatagaaa gtttcagcca
     6001 agtttgacaa agtcagctca aattactgtt tgaagtttgt agatataagc gacaaaaaca
     6061 atcatactgc accttttgtt gacagtctac tccagacata tcatagttca agtaaatact
     6121 ttgaaatcca acagttctta taggtgctat tgtattctaa gaaatcaata gaagagtttc
     6181 taagcaaatc tctaatactc aataaaaatc aaagagcaaa ctagaaagct agccgcaggt
     6241 tgctcaaaac actgttttga agttgcggat agggctgaca tggtttgaag agattttcga
     6301 agagtataat ttacgtgttc ccaagatgga gaagttagac tagtacactg gcacttctaa
     6361 accattgcta gcaattgatt tgttcatatt taatttcatt ttttccataa atgggtatta
     6421 gatataaaca gcaaaatatt tccgatacgt gtcattcttg aatttccaat catctaaaac
     6481 aagtaaagga taatcaatcc cctgtatatc aaggaattgg ctaccctttt tactttttta
     6541 cacattctgt ttgatagatt cattttaaca tcacgagcat actccaatgg aaatcgctag
     6601 gcaagagata aactttcaga tatccgcaga gagatcatcg cctctttttg tcgcaagcat
     6661 tctcctctcc taatcatttt ctatcttatc ctctacctga ggataaagag tcgttcccca
     6721 aatagaaatc gtccgcttac gcactagtgg caaatcggtt ttttcataaa ccgtacgcca
     6781 ccattcccag gcaagcccgg tacactctct aattttgaca gagagattac gaacattccc
     6841 ttttaaagga atactagtgg taaagtgagc cgtcaaatcc tgcccatttc tgtcccaagc
     6901 cttagcagtt aagacttcct taccttgatg atcataggat aattcatccc aagtaatata
     6961 atattgggca acataggcac cactatgatc cagcagtaaa tctccgtttc tgtaagctgt
     7021 aaccttagtc tcaacatagt ctgtactgtt ttgaaaggtc gcaactacat tgtcacgtaa
     7081 aaaagaagtt gtataggaa
//
LOCUS       DAVDZK010000067         6985 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVDZK010000067 DAVDZK010000000
VERSION     DAVDZK010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6985
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.068"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..786
                     /locus_tag="VUX16_002054"
     CDS             <1..786
                     /locus_tag="VUX16_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HET8124943.1"
                     /translation="NWKIPCDAVKPTDGRYKTKESLILVLGDKLETLKKRRPLTEGEV
                     ERLNEEFLVEYTYNSNAIEGNTLTLRETDMVLRGLTIDRKSLKEHLEVIGHKDAFDYV
                     RQLVRENAPISEKIIKDIHYLVLADKKEDRGVYRRVPVRIMGAAHEPVQPYLIVPKME
                     ELLERYENSKEDIVTRLARFHIEFESIHPFIDGNGRTGRLLVNLELMKAGYPPIDIKF
                     TDRLKYYEAFDHYHLKDDLSAMADMFALYLNQKLDLYLSILDK"
     gene            1092..>6985
                     /locus_tag="VUX16_002055"
     CDS             1092..>6985
                     /locus_tag="VUX16_002055"
                     /inference="COORDINATES: protein motif:HMM:NF020018.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473604.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET8124944.1"
                     /translation="MKKSYRDDNGEKVFRYSIRKYHFGAASVAVAALMFFANGAVAAS
                     ETITPTTASDVVKAGSDGNADGNPASSDEGDSKQALTDKPAELKAADELKTQEAPAEG
                     ANQTSSTGILQPRTLKNNQSDYDPIPIEDDEDDVRDGLFSSENPVTTIQPRSSHSVTG
                     RALQGDTQAPKVSLGSALLPTSESTATTPLYRIRQGQAFTPKLKVWNNSGSIKSLDIT
                     GIPNGVTKHRFGTDFSEQTAATEMNPYSGSTLSGNVPDTQAVGQHIAQITVKDASNNV
                     ATYYLKYEVYPARVEAKQGRFGQVKDKALIHGDDPANYIKFKSANGKEVQKPADVKVT
                     WERKPSTVEAGLNKTGLVKVTYHVTDENGVVRDEVQTVTINTPVYHATLVQNPFKTTY
                     GREFVNKNQPRDGRRYIDYNGRSHFNLSNLRVYWESSNIRGQQFSDGTRPWPTNYLGK
                     KREKLMVRYPGDNGRYDNRNDDYGARYEELDGTFIVKPVKPNIQTSLGKVGKNTLTVN
                     NVNSGTTVVVYDAANPNNLKELGRTMVAKEGDYRIKNGVEVPLNSGVTFKKDQKIVTK
                     VIYKITDDDQRTESDVSDIWTVKESLIANGIHVIKGESYTGTAKDRIRYNDNVDAEQR
                     TGLPNNATASWAQNPNYTTLGTSNYTANVTVPGQGSATVNVPVHVYAPANLKATSYNN
                     KQGTLSNGANPENYIEFKDGNTVVTKPNNVTVRWQGGVAPRINTPGHNRGVIEVVYPG
                     NAGASSTVVKTFTVQLPTYHTTATATEYTRTIGENFAKTTARDYATTHNWNVGGSQYV
                     WKNDETANREYSAENWGKVNGDWLGKKKNKVKVYYGNDNGSNSHSENLAEETEEITFV
                     TKPKTPSITATALNGKAGQRNQQVTVNNVTPGTTVELYNGDTKIGSVDVSKANNEAYT
                     DIKTVTVAVNGQLPLSSNIRAKTIYMPNNANEKVESDFSTSVQSTTEGPQAPEISQNP
                     ENLLVKATVGQGGSTKVTLTYTDANGRVKEVGFTKNGQFWDKDDANADTTVSITNESN
                     GTGEIQLQPGTAQEGTTVTVKQKTATSEFSTPATTKALGRLNGLTNVAQADGSVDITV
                     PDTATKFDLTYRNQQNNTTETLHYSKDAQGRWGNVTGITADGNRFTLPKGLVTDGTTV
                     SVIASNDNKTTKTVTSDAKFEMPDATTHTQRENGDGVITLPSTADSVTVTYTDAQDTA
                     KTVTVTKNASNQWASTAALPEGVTLNGNELNVAYKNINSNGNVKTVSTRGTGNVRSQE
                     AVENIELNHIPISTQAVVIAAGATPTNDDLGRGVTFAKRSITAKSTPAAVPAGTSAEI
                     PATLTYNDGSTEDVTITVKSKPTAPSFNNLENHGTYSGLSSISKVISGTAMPGAEKVK
                     LTLQDGTVKEITPQADGSWSYTLGATEYLTQSFSGQFNGVFNQNKVKAVQVKDGVESE
                     ETTANVAPGQATVDSVYKAGRAITVNIPHDIEAGYVRVNGTDYGIQKVNGTWRVISTA
                     PNAAKLEISNTVVDPTNKAVTKVTFSVKNNDDALYTPPFKIGNSPVRFRTYYSKNGTI
                     NTPTPQIRGTDGWADSPTPKNTKPTVNFTADHTIEENKVFASPTVEELKDYFEGHDAE
                     DDASLTVGYSASNRGKLRVQVFTQDTNQSVRANTQGRIDPGNYRLVLSTNDAADAESE
                     PITRNITVKTYADVYRDKVLYPTNVDKVTYDDTAISNGNFTTAAKTSFKDKIQELNGT
                     VLPASTRYTVGTTDDKAKVAVINFPDGSTIDISHAVVAKPTVPTVTRTHADKVSDADR
                     TISGTALQSATKVTIYFQDGRGEQGHADVVPVNGQWTYTLPTGRYLRQTEHTSLPGSS
                     SVPVNVTQTVFDATSDKTAVYVAKDRNFTGKQIVGTKGSQELTALKNDAKKGINYTER
                     NTPKDFPSDFDATWKETPDITTVGTRTYTAKVFEKDKGDAVSQEISVEVTVKADTPDA
                     VAASYK"
BASE COUNT         2397 a         1313 c         1512 g         1763 t
ORIGIN      
        1 aattggaaaa taccatgtga cgcagtaaag ccgacagatg ggagatataa gactaaagaa
       61 tcactcattc tagtcttggg agataagtta gaaactctaa aaaaacgacg tcctttaact
      121 gaaggagaag tggaaagatt aaatgaagaa tttttagtag aatatacata caattctaat
      181 gctattgaag gaaatacact gactttacgt gaaacagaca tggttcttag aggacttaca
      241 attgaccgaa aatccttaaa agagcatttg gaggtcattg gacataaaga tgcttttgat
      301 tatgtaaggc aacttgttcg tgaaaatgct ccaatatctg aaaaaattat aaaagatatt
      361 cactatttgg ttttggcaga caagaaagaa gatagaggtg tgtatcgaag agttccagtt
      421 cgaattatgg gagcggctca tgaacctgtg caaccctatt taattgttcc taagatggaa
      481 gagttactgg aacgatatga aaatagcaaa gaagatattg ttactagact tgcccgtttt
      541 catattgagt tcgaatctat tcatcccttc attgatggaa atggaagaac agggaggttg
      601 ttggttaatt tggaactgat gaaagcaggt tatccaccta ttgatataaa atttactgat
      661 agattaaaat attatgaagc ttttgaccac tatcatttaa aggatgattt atcagccatg
      721 gcagatatgt ttgctctata tttgaatcag aaactagatt tatatttatc tattttagat
      781 aaatgagaat aaaagaattc cgtagaactt caaatttttg tcaatagagc tcttttaaga
      841 taatctaatc tatagactag gctggttcgg tatctttctg aaaaaatcct taacaaacgc
      901 cagcaaaaag ttagcgtttt tctgttcaaa tttgcgaaaa tagtatataa tagtactgtc
      961 tcaaaacttg tcttttgaca agcctgggaa caaaaagaaa aaaacatatc ctttccttaa
     1021 atactaaaat atttaggggg gggggtattt tttagtacct ccagaaagga aaaacgagag
     1081 gtaattcaat catgaaaaaa tcatatcgtg atgataacgg ggaaaaggtc ttccgttatt
     1141 ccattcgtaa gtaccacttt ggtgctgcca gtgttgcggt agcggctctg atgttttttg
     1201 ccaacggagc tgtggcagcg agtgaaacga ttactccaac tacggcaagt gatgtcgtta
     1261 aggcaggttc tgatggcaat gcagatggaa atccagcgtc ctcggatgag ggagactcca
     1321 agcaagctct gactgacaaa ccagctgaac tcaaagcagc tgatgagctg aaaacgcaag
     1381 aagcgccagc tgagggagcc aatcaaacaa gtagtactgg aatcctccag ccgcggacgc
     1441 tcaaaaacaa tcagtctgac tacgacccta ttccaattga ggatgatgag gatgacgtaa
     1501 gagatgggct gttttcttcg gaaaatccag taaccactat ccaaccacgg agctctcact
     1561 ctgtaaccgg tcgcgcactt caaggcgaca cacaagcgcc aaaagtgagt ttgggcagtg
     1621 ctcttcttcc gactagcgaa agtacggcta ctacgccatt gtacagaatc cggcaagggc
     1681 aagcttttac accgaaatta aaagtttgga ataactcggg atctatcaaa agcttagata
     1741 taacgggaat accgaatgga gtgaccaagc atagatttgg aactgacttt tcagaacaga
     1801 cggcagctac tgaaatgaat ccctacagtg ggtcaacact tagtggtaat gtgccagata
     1861 cacaagcagt aggacaacat atagctcaaa ttactgtaaa agatgcatcg aataatgtag
     1921 ctacttacta cctaaaatat gaagtctatc cagcaagagt agaagctaag caaggtcgat
     1981 ttggacaagt caaagataaa gccttgatac atggcgatga tccagctaac tatatcaagt
     2041 ttaaaagcgc taatggaaaa gaggttcaaa aaccagcaga tgtaaaggtg acgtgggaac
     2101 gtaagccaag tacagtagaa gcaggtctta ataaaacagg actagtaaag gttacctacc
     2161 atgtaacaga tgaaaatggt gtggttcgag atgaagttca aactgtaaca atcaataccc
     2221 ctgtctatca tgcaactctt gtacagaatc cctttaaaac aacctatggt agggaatttg
     2281 tcaataaaaa tcaacctaga gatggtagac gctacattga ctataatgga agatctcatt
     2341 tcaacttaag caatctacgt gtttactggg agagttctaa tataagaggt cagcaatttt
     2401 ctgatggtac gcgaccatgg cctaccaatt atttaggtaa gaaacgtgag aaattgatgg
     2461 ttcgctatcc aggtgataat ggcaggtatg ataatcgtaa tgatgactac ggtgcacgat
     2521 atgaagaact agatggaact ttcatcgtta agccagtcaa accaaacatt caaaccagtc
     2581 ttggtaaggt aggaaaaaat actctgactg tcaataatgt caatagtgga acaacagttg
     2641 tggtctatga tgctgccaat ccaaacaatc tcaaggaatt gggtcgtaca atggttgcta
     2701 aagaagggga ttacaggatt aaaaacggag ttgaagtgcc actaaactct ggtgtaactt
     2761 tcaaaaaaga ccagaaaatt gtcaccaagg tcatctataa gattacagat gatgaccaac
     2821 gtacagaatc tgatgtcagt gatatctgga cggtcaagga aagcttgata gcaaatggca
     2881 tccatgtcat caagggcgag agctatacag gaactgccaa agaccgtatc cgttacaacg
     2941 ataatgtaga tgcggaacag cgaacaggcc ttccaaacaa tgccacagca agctgggcgc
     3001 aaaatccaaa ttatactact ttgggaacaa gcaactacac tgccaatgta acagtgccag
     3061 ggcaaggaag cgcgacagtt aacgtgcctg tgcatgtcta tgcaccagct aacctgaagg
     3121 caacttctta caataacaag caaggtaccc tatcaaatgg tgccaatcca gaaaactata
     3181 ttgaatttaa agatggaaat acagttgtca ctaaaccaaa taatgtgact gtgcgttggc
     3241 aaggtggtgt agcacctcga atcaatacac caggtcacaa tagaggagtt attgaggttg
     3301 tctatccagg aaatgctgga gcaagctcta cggttgttaa gacctttacg gttcaattac
     3361 caacctacca tacaacagct actgctacag agtacactcg taccattggc gaaaactttg
     3421 ccaaaacaac tgctcgcgac tatgcgacta cgcataattg gaatgtaggt ggcagtcagt
     3481 acgtatggaa aaatgatgaa accgctaatc gtgaatacag tgcggaaaac tggggcaagg
     3541 tcaatggcga ttggcttggt aagaagaaaa ataaggttaa ggtttactac ggaaatgata
     3601 acggaagcaa ctcgcattct gaaaatctag ccgaagagac tgaagaaatc acctttgtga
     3661 ctaagccaaa aacaccaagc atcactgcga cagctcttaa tggaaaagcg ggtcaacgca
     3721 atcaacaagt gacagtaaac aatgtcacac cagggacaac agttgagctc tacaacggtg
     3781 atacgaaaat tggttctgta gatgtatcaa aagctaataa cgaagcttac actgacatta
     3841 aaactgttac agtagcagtt aatggtcagt taccactttc atctaatatt cgtgcaaaaa
     3901 cgatttatat gcctaataat gcaaatgaaa aagtagaatc tgattttagt actagtgtgc
     3961 aaagtacaac agaaggtcca caagcgccgg aaatttctca aaatccagaa aacttattgg
     4021 tgaaagcgac tgtaggacaa ggaggttcta ctaaggttac tcttacttat acagatgcta
     4081 atggacgtgt gaaagaggtt ggattcacga aaaatggtca attctgggat aaggatgatg
     4141 ccaacgctga tactactgta tcgattacta atgagtctaa tggaacaggt gaaattcaac
     4201 ttcaaccagg tacggctcaa gagggaacaa cagtaacagt taagcaaaaa acagctacat
     4261 cagaatttag tactccagcc actactaaag ctttaggacg cttaaatggc ttgacgaatg
     4321 tagctcaagc agatggttcg gtagatatta ctgtaccaga tacggctacg aagtttgatt
     4381 tgacctaccg caaccagcaa aataatacaa ctgaaacact tcactatagc aaagacgccc
     4441 aaggacgttg gggaaatgtg acaggcatta ctgctgacgg caatcgcttt accttgccaa
     4501 aaggtttggt gactgacggg acaaccgttt ctgtcatcgc atcaaatgac aataagacaa
     4561 ctaagacggt tacgagcgat gctaagtttg aaatgccgga tgctacaact catactcagc
     4621 gtgagaatgg tgacggtgtt attacgcttc caagtactgc tgactctgtg acggtcactt
     4681 atacggacgc tcaagatact gctaagacgg tcactgtgac taagaatgct agcaatcaat
     4741 gggcaagtac tgctgccttg ccagaaggtg tgactttgaa cggtaacgag ctcaatgttg
     4801 cttataagaa tatcaatagt aacggaaatg tgaaaacagt ttcgacacgt ggtactggca
     4861 atgttcgttc tcaagaggct gtcgaaaata ttgaattgaa ccatataccg ataagcactc
     4921 aagcggttgt tatcgctgct ggtgcgacac cgacaaatga tgatttagga cgtggtgtga
     4981 catttgccaa acgttctatc actgctaagt caacaccggc agctgttcca gcaggaacca
     5041 gtgcagaaat tccagctacc ttgacttata atgacggctc tactgaggat gtcactatta
     5101 ctgttaagtc taaaccaaca gcaccaagct tcaataatct tgaaaatcat ggaacatata
     5161 gcggattatc ctctatttct aaggtgattt caggtacagc tatgccaggt gcagaaaaag
     5221 ttaaattgac tttacaagac ggtacagtta aagagataac tcctcaagct gatggaagtt
     5281 ggtcttatac tttaggagct actgaatact tgacgcaaag cttcagtggt cagtttaacg
     5341 gagtattcaa tcaaaataag gtaaaagctg tccaagtgaa agacggtgta gagtcagagg
     5401 agactacagc aaacgttgca ccaggtcaag cgactgttga ttctgtttat aaggcaggac
     5461 gtgcgattac ggtcaatatc cctcatgata ttgaagctgg ttatgttcgt gtcaacggaa
     5521 cagactacgg tattcaaaaa gttaatggta cttggagagt aatctcaaca gcaccaaatg
     5581 ctgccaaatt ggagatttca aatacagttg ttgatccaac gaataaagct gtcactaaag
     5641 tgacctttag tgttaagaat aatgacgatg ccttgtatac tccaccattt aaaattggga
     5701 atagtcctgt aagattcaga acgtattatt ctaaaaacgg aaccattaac actccaacac
     5761 ctcaaattcg agggacagat ggatgggctg attctcctac acctaagaac actaaaccaa
     5821 ctgtaaactt cacagctgat catacaatag aagaaaacaa ggtgttcgct tctccaactg
     5881 tagaagagtt gaaggattat tttgaaggtc atgatgctga agatgatgca agtttaactg
     5941 taggttactc tgcttctaat agaggtaaat tacgtgttca agtattcact caagacacta
     6001 atcaatcagt aagggctaat actcaaggac gtattgatcc aggtaattac agacttgtct
     6061 tgtctacgaa tgacgcggca gatgcagagt ctgaaccgat tacaagaaat atcacagtga
     6121 aaacttatgc tgatgtttat cgtgataagg ttctttatcc aacgaatgtt gataaggtga
     6181 cttatgatga tacagcgatt agtaatggta actttacaac agcagccaaa acaagcttta
     6241 aagataaaat tcaagagcta aatggcacgg tgcttccagc atcgacaaga tatacagtag
     6301 gaactacgga cgataaggcg aaagtcgctg tgattaactt cccggatggt tctactattg
     6361 atatttcgca tgcggttgta gccaaaccaa cagtgccaac ggtaactcgc acacatgctg
     6421 ataaagtatc agatgctgac agaacaattt ctggtacagc ccttcaaagc gcgacaaaag
     6481 taactattta tttccaagat gggcgtggtg aacaaggaca tgcagatgtt gtgcctgtaa
     6541 atggtcaatg gacttacact cttccaacag gacgttatct ccgccaaaca gaacacactt
     6601 cattaccggg ttcttcctct gtacctgtaa acgtaacaca aacggtattt gatgcaacaa
     6661 gcgataaaac agctgtttat gtggcgaaag accgtaactt tacaggaaaa caaatcgttg
     6721 gaactaaggg tagtcaagaa ttgactgctt tgaaaaatga tgctaaaaaa ggaatcaact
     6781 atactgaaag aaatactcca aaagactttc caagtgattt tgatgctaca tggaaagaaa
     6841 caccagatat tacaactgta ggaacaagaa cttacacggc taaggtgttt gaaaaagata
     6901 agggtgatgc agttagccaa gaaatttcag ttgaagtcac tgtcaaagca gatactccag
     6961 atgcagtagc agcaagctac aaaca
//
LOCUS       DAVDZK010000068         6890 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVDZK010000068 DAVDZK010000000
VERSION     DAVDZK010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6890
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.069"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..>6890
                     /locus_tag="VUX16_002056"
     CDS             <1..>6890
                     /locus_tag="VUX16_002056"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124945.1"
                     /translation="EPKQALTDKPAELKAADEVKTQEAPAEGANQEQAGDESETTGVE
                     SNSAQPETNPASQEAPQAEGEGKQDQSTPVSDQTSSTSLLQPRVLKSKQSDYDSIPLG
                     DDEDDEDDVRDGLFSSENPVTTIQPRSSRSVQPKENSSGVHSVRAEAKQSRFGQVKGK
                     PLIHGDNPANYIKFKNANGQEVQKPAGVDVAWAEKPSTTQEGLNKTGRIKITYHLTNE
                     NGMEVNREEFVTISTPVYHATLTQNRYVTTYGGEFTNRINPTDGRRYINYNAKSHFQL
                     NNLRAYWEHSSGSNGSTYSSVIRDWNTRYLGKKREKLMVRYPSDDGIYRSNRDDGGGR
                     YEILDGTFIVKPVKPSIQTSLGKVGKNTLTVNNVNSGTTVVAYDMANPRIPREIGRVS
                     VPKDGDYRIKNGIELTLNSGEVLRKDQKIATKVIYEITNADQRTESDSSDTLTVKESL
                     VANGIHVIKDETYTGNVKDRIRYNDDTDADRRTAFPNNASASWVQNPDYSRLGTRNYS
                     ANVRIPGQGDARVDVPVHVYAPASLKASSYNNKQGTLSNGTEAENYIQFRDGNATIDK
                     PNNVTVRWKDGQAPDVSRPGTQQKTIEVVYPGNDGPSSTVIREYQVTFTSYHAQAQKR
                     EYTRTIGENFTSTTAKSYVKKADGSPELPQETEYAWKKDETANREYGSETWGKVNDDW
                     LGKKTNKIKVYYPNADGGNNKADNLAEETEEITFITKPAKPRIASNLTGQAGTRSNVV
                     IQNATPGTTLELRDGDTVLGKVEVPKNNSLYSQLTTATITPTADIPASANITVKSIYS
                     PNNQDQRVESDSSDAVASTQITVSAKGTIQTLAGTGHIAGLSNLNKATLSTLLNLSDG
                     SAVADGTTGRWESGQNIAKGQAGTRTEKLFVRLPGHTKEQEVTFTVKTLAVPSAKAVV
                     KDKGQDIVADDLSNYVTVEGQTGLSWKGNPSKVEVGKTLPKIKVTYPRAGQNGIAVTD
                     IQDQEVDAKVYSLEVNGVAKTRVTVGETFDPVAADYVTQVANTETLPSGVSYAWKNGN
                     KPSSARVGKETYTVETSFGIGNDVPAELRGQKVETQVEVTVLSTKPSQPELGQNRNDL
                     AITAVVGKENANKAVITFRDDADQEQTVTFEKGANNQWDKVGGINQPTVQILNNNDGT
                     AIVHLTAGTAKVGSSVSIKQQKADSDYSEAATLVAKERLDGVSATSKDDGSVDVVVPS
                     EAKKASVTYTPEGQSQAKTVELAKAQDGTWSAPANSGLLVNKDNTTGILTITVPASQV
                     VDGSKVVGNADSDSKLSIDAEARAKAPQPVEFDSSIRHNGDIVLTLPNNADTATINYP
                     VSDTELKTATATKGQDGSWRLSPDSGLELASTNGVTKITLAYTKLSGNRTVTASAKAG
                     SGEGESKERTFTKTVPAHTTPTTQNVVIAANATPTDDQLLTGVIANNKQSVAAKQTQT
                     AIAAGTTKEIPATLTYTDGSTEEITITVQSKPTAPTVNGLESRARVAVPGLLSTARTI
                     TGQAMQGAEKVKLTLQNGSEKEVDVAADGSWSYTLAADEFLTQTISNSNAKYSSTKIR
                     LVQVKDGLESEPKDIDILMGRATIDTPLRAGRDITLHIPHDTTSGYIRIGGSVERGGV
                     DIGLKKVNGVWTLDTDANRASKLELVSETDPTNPALTKVTLKVKATDNASYSPPFTIG
                     GDSGNVKFRAHYYSGRDIGAVVPMGRQGQFEWILSGQPTNTRPTVGWETGKEIQDGQK
                     IPSPTVDELKDFFKGEDAEDDAGLTVGYSASNRGKLRVRLYTSGTNQTVRTNVRGRID
                     PGNYRLLLSTIDAAGVESNILERNVIIQSYADYYRDAVQYPTTAQKVTYSDTDITNGN
                     FTAAAKTGNFTAAAKTRFKDKIETINRQNTQLPTSVTYSVGTTDDKAKVAVINFPDGS
                     TIDISHSQVAKPDVPTITPTDTEQQGMPKVTDADREISGTALQNATKVTLKLQTGKGI
                     EIVKEITVNNTKDFAALVPGEGLLKNGVWKYKLADGQYLRQTDATAEPGSSSLPLKAT
                     QTVFDAVSDDTSIYVANKRTVEGKKIEGEVGSPDLKKYIDKPQDAVVYKEKGQEKPFP
                     SDFIAKWENTPNFDTVGTFTYKVKFYEKDGNTPADHISEGVEVTFVVKSKAPAILDYT
                     NRDNGETLVNIPQDADEVVFSILRSDTAVDTITVKKSEGWTATGIQKRDNTWVFPANS
                     VHGNRTVTAVATAGKGDTKSVEMLTLITTLAHDVTVNEITKPTKGNPTSQDLLDAVEV
                     TNKKSVALKQGENYPETFGTHQIHLIVTYQDDSTEEKVANYTVPDTRD"
BASE COUNT         2354 a         1355 c         1591 g         1590 t
ORIGIN      
        1 agagcccaag caagctctga ctgacaagcc agctgaactc aaagcagctg atgaggtgaa
       61 aacgcaagaa gcgccagccg agggagccaa tcaagagcaa gcaggagatg agtctgaaac
      121 gactggagta gaatccaact ctgctcagcc agagacaaat ccagctagtc aagaggctcc
      181 tcaagcagag ggagaaggaa aacaagacca gtcgactcct gtttccgacc aaacaagcag
      241 caccagcctc ctccagccgc gggtgcttaa gagcaagcag tctgactatg actctattcc
      301 acttggcgat gatgaggatg atgaggatga tgtaagagat gggctgtttt cttcggaaaa
      361 tccagtaacc actatccaac cacggagctc tcgctcagtt cagcctaaag aaaatagttc
      421 tggagtccat tcagtaagag cagaagccaa gcaaagtcga ttcggacagg tcaaaggtaa
      481 acccttgata catggcgata atccagctaa ctatatcaag tttaaaaacg ctaatggaca
      541 agaggttcaa aaaccagctg gagtagatgt tgcttgggcg gaaaaaccaa gtactacaca
      601 ggaaggactt aataaaacag gtcgtatcaa aatcacctac cacctaacga atgaaaatgg
      661 tatggaggta aatcgagaag aatttgtaac tattagcacc cctgtctatc atgcgacttt
      721 aacacagaac cgctatgtaa caacctacgg tggggagttt accaatcgta taaatcctac
      781 ggatggtaga cgctatatta actataatgc aaagtctcat tttcaactaa ataacttgcg
      841 tgcttactgg gaacattctt ctggttcaaa tggctcaacc tattcctctg ttattcgaga
      901 ttggaatact cgttatttag gtaagaaacg tgagaaattg atggttcgct atccaagtga
      961 tgatggcatc tatcgtagta atagagacga cggcggtgga cgatatgaaa tactagatgg
     1021 aactttcatc gttaagccag tcaaaccaag cattcaaacc agtcttggca aggtaggaaa
     1081 aaataccctg actgtcaata atgtcaatag tggaacaaca gttgttgctt acgacatggc
     1141 aaatcctagg attcctcgtg aaattggacg tgtatcagtt ccaaaagacg gggattacag
     1201 gattaaaaat gggattgagc ttacgcttaa ctctggtgag gtcttacgaa aagatcaaaa
     1261 aattgcgact aaagttatct atgagattac aaacgctgac caacgcacag agtcagatag
     1321 tagtgatacc ctgaccgtca aggaaagttt ggtagctaat ggaattcatg tcatcaagga
     1381 tgaaacttac acaggcaatg tcaaagaccg cattcgttac aatgacgata cggacgctga
     1441 tcgccgcaca gcgttcccta ataatgcaag tgcgagctgg gtacaaaatc cagactatag
     1501 tagattaggt acacgtaact acagtgccaa tgtaaggatt ccaggtcaag gagacgctag
     1561 ggttgatgta ccagttcatg tctatgcgcc agcgagtctg aaagcaagct cttacaataa
     1621 caaacaaggt actctatcta atggtacaga agcagaaaac tatatccaat ttagagatgg
     1681 caatgcaacg attgataaac caaataatgt cactgtgcgt tggaaagatg gacaagctcc
     1741 agatgtttca cgaccaggaa ctcaacaaaa aacaatagaa gttgtttacc caggcaatga
     1801 cggacctagc tcaacagtca tcagagagta tcaagtgacg tttactagct atcatgcaca
     1861 agctcagaaa agggaatata ctcgtacaat tggggaaaac tttacctcaa ccacagctaa
     1921 gagctatgtc aaaaaggcag atggttcgcc tgagttgccg caagaaacag agtacgcttg
     1981 gaagaaggat gagacagcta atagagagta tggttcggaa acatggggca aggtgaatga
     2041 tgactggctc ggtaagaaga ccaataagat taaagtttac tatccaaatg cggatggagg
     2101 caataacaag gcagataatc tagctgaaga aaccgaagaa attaccttta ttacgaaacc
     2161 agctaaacca agaattgcaa gcaatttgac aggtcaagca ggcacacgtt caaacgtagt
     2221 gattcagaat gcgacaccag gaacaacgct tgaattgcgt gatggtgata ctgttttagg
     2281 taaggttgaa gttccgaaaa acaatagttt atacagtcaa ttgacaaccg caactattac
     2341 gcctacggct gatatccctg cttcagcgaa tatcactgtc aagtctatct attcaccaaa
     2401 taatcaggat caacgtgtgg agtctgacag tagcgatgca gtagcaagta cccagattac
     2461 tgtgtctgca aaaggaacca ttcaaacctt ggcaggaacg ggtcatattg ctggtttgag
     2521 caacctcaat aaggcaacgc tttctacctt actcaatctt tcagacggaa gtgcggtcgc
     2581 tgatggcaca acaggacgtt gggaatctgg tcaaaacatt gccaaaggtc aggcaggcac
     2641 acgaactgaa aaactctttg ttcgcttgcc tggtcataca aaagagcaag aagtaacttt
     2701 tacagtcaag acgctagctg ttccgagcgc taaagcagtt gtgaaagaca aaggacaaga
     2761 tatcgttgca gacgacttga gcaactatgt tacagtagaa ggacaaactg gactcagttg
     2821 gaaaggaaat ccaagtaaag tagaggttgg gaaaactctt ccaaaaatca aggtaaccta
     2881 tccaagagct ggtcaaaacg ggatagccgt gacagatatt caggatcaag aggtagatgc
     2941 taaggtatac agcctagaag ttaatggtgt tgccaagaca agagtaactg taggtgaaac
     3001 atttgatcca gttgctgctg actacgtcac acaggtagcc aatacagaaa ctcttccatc
     3061 aggtgttagc tatgcatgga agaatggcaa taagccaagt tcggctagag tagggaaaga
     3121 gacctacacg gtagagacaa gcttcggtat aggaaatgat gtccctgcag aacttcgtgg
     3181 tcaaaaagtt gaaacgcagg tcgaagtgac agtcctttct actaaaccaa gtcagccaga
     3241 acttggtcaa aaccgtaatg atttagcaat cacagcggtt gtcggaaaag aaaatgccaa
     3301 taaggcagta atcacgttta gagatgatgc tgatcaggaa cagactgtga cctttgaaaa
     3361 aggggctaac aatcaatggg ataaggttgg aggaattaat caaccgacag ttcaaattct
     3421 aaataataat gatggaacag ctatagttca cttgacagca ggtacagcta aagtcggtag
     3481 ttctgtaagc atcaaacagc aaaaagcaga ttcggactac agtgaagctg caactttagt
     3541 agctaaagaa cgtttggatg gtgtcagcgc gacaagtaaa gacgatggtt cggtagatgt
     3601 cgttgtacca agtgaagcca agaaggcttc tgtgacgtat actccagaag gtcaaagtca
     3661 agcgaagaca gttgagttag ccaaggctca agacggcaca tggtcagcgc cggcgaattc
     3721 aggtcttcta gttaataaag acaacacaac aggcattctg accattacgg ttccagcaag
     3781 ccaagtagta gacggtagta aggttgtagg aaatgcagat agcgatagca agttgagtat
     3841 agatgcagaa gcgagagcga aagcaccgca acctgtcgaa tttgatagct ctattcgtca
     3901 taatggagat atagtgttga cgctcccaaa taatgcggat acagcaacta tcaactatcc
     3961 agtgagtgat acagagctga aaactgctac tgcaactaag gggcaagacg gtagctggag
     4021 gctttcacct gactcaggtc ttgagcttgc tagcacaaat ggagtcacta agataacgct
     4081 agcatataca aaattgagtg gcaatcgtac agtgactgca agtgctaaag caggaagtgg
     4141 tgagggagag agtaaagagc gtacctttac taaaacagtt ccagcacaca caactccgac
     4201 aacccaaaac gttgtcatcg ctgcaaatgc gacaccaact gatgaccaat tattgacagg
     4261 tgtaatagct aacaataaac aatccgtcgc agctaaacaa acacaaactg ctattgctgc
     4321 aggaactaca aaagaaattc cagcaacttt gacctacacg gatggttcga ctgaagaaat
     4381 cactataacg gttcagtcta agccgacagc accgacggtg aatggtttag aaagtcgtgc
     4441 aagggttgcc gtaccgggtc ttttatcaac tgctcgcacg attacaggtc aggctatgca
     4501 gggtgcagaa aaagttaaat taactttaca aaatggtagt gagaaagaag tagatgtggc
     4561 tgccgatggt agttggtctt atacgcttgc agcagatgaa ttcctgactc aaacaatatc
     4621 aaatagtaat gctaaatata gttctacgaa aatccgtctt gtgcaagtga aagatggtct
     4681 agaatctgaa ccaaaagaca ttgacatttt gatggggcgc gccactattg atacgccact
     4741 tcgagctgga cgtgatatca cccttcacat tccgcatgac accacttctg gctatatccg
     4801 cataggaggt tcggtagaac gaggtggagt agatatcgga ctcaagaagg tgaacggtgt
     4861 ctggactctt gatacagatg ccaatagggc aagtaagtta gaacttgtga gtgagacaga
     4921 cccgacgaat ccagctttga ccaaggttac gctcaaagtt aaagccacgg ataatgcctc
     4981 gtacagtcca ccgtttacca ttggaggtga cagtggaaac gtgaaattca gagctcacta
     5041 ttacagtggt agagatatcg gtgcagtagt tccgatgggg agacaaggtc aatttgaatg
     5101 gattttgtct ggtcaaccaa ccaatactag acctacagtt ggctgggaaa ctggtaaaga
     5161 aatccaagat ggtcaaaaga ttccatcacc tacagtagat gagttgaaag acttctttaa
     5221 aggggaggat gctgaagatg atgcaggtct cactgtagga tactcagcct ctaatagagg
     5281 taaattacgt gttcgtttat atacaagtgg aacgaaccaa actgttagaa caaatgtccg
     5341 aggacgaatc gatccaggta attatagact gctcttgtct actattgatg ctgcaggggt
     5401 ggagtctaat atccttgaaa gaaatgtcat cattcaaagt tatgcagatt actatcgtga
     5461 cgctgttcag tatccaacta ctgctcaaaa ggtaacctac agtgatacag atatcactaa
     5521 tggtaacttc acagcagcag ccaaaactgg taacttcaca gcagcagcca aaacacgttt
     5581 taaggataaa atagagacta tcaatcgcca aaatacccaa cttccaacta gtgtgactta
     5641 tagcgtagga actacggatg ataaggcgaa agtagctgtg attaacttcc cggatggttc
     5701 tactattgat atttctcatt cgcaggtagc caaaccagat gtaccgacaa tcactccgac
     5761 ggatacagaa caacagggga tgccgaaggt aactgatgct gatagagaaa tttctggtac
     5821 tgcccttcaa aatgcgacaa aagtgacatt gaagttgcaa actggtaaag ggatagagat
     5881 tgtaaaagaa attacagtta ataatacaaa agatttcgct gccttagtac caggagaagg
     5941 gctcttaaaa aatggagtat ggaagtataa gctggctgac gggcaatact tacgtcaaac
     6001 agatgcgaca gcagaaccag gctcgtcctc actcccatta aaagcaacac aaactgtatt
     6061 tgatgcagtt agtgatgata cgagtatcta tgttgccaat aaacgtactg tagaaggtaa
     6121 aaaaattgag ggagaagttg gcagtcctga cttgaaaaaa tacatagata aaccgcaaga
     6181 tgccgttgtc tataaagaaa aagggcaaga aaagccattc ccaagtgact ttattgccaa
     6241 atgggaaaat actcctaact ttgataccgt tggaaccttt acctataaag taaaatttta
     6301 tgaaaaagac ggcaatacac cggctgatca cattagtgaa ggtgttgaag ttacctttgt
     6361 agtcaaatca aaagcaccag caatcttaga ctacactaat agagataacg gtgaaactct
     6421 tgtgaatatt ccgcaagatg ctgatgaagt tgttttcagt atccttagaa gtgatacagc
     6481 tgtagatact ataactgtaa aaaaatctga aggttggacg gcaacaggga ttcaaaaacg
     6541 tgataacact tgggtatttc cagctaactc agtacatggc aaccgaacag taacagcagt
     6601 tgcgacagca gggaagggtg ataccaagag tgtagagatg ctgacattga ttacaacact
     6661 tgctcatgat gttactgtta atgaaattac taaacctact aaaggaaatc caacatccca
     6721 agatttgctt gatgcagtag aagtaactaa taagaaatcc gtagcactga aacaaggaga
     6781 aaattatcca gaaacttttg gaactcatca aatccacttg attgtaacct atcaagatga
     6841 tagtacagaa gagaaggtag ctaattatac agttccagat acaagagatg
//
LOCUS       DAVDZK010000069         6853 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVDZK010000069 DAVDZK010000000
VERSION     DAVDZK010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.070"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(<1..532)
                     /gene="nusG"
                     /locus_tag="VUX16_002057"
     CDS             complement(<1..532)
                     /gene="nusG"
                     /locus_tag="VUX16_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET8124946.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
     gene            complement(587..763)
                     /gene="secE"
                     /locus_tag="VUX16_002058"
     CDS             complement(587..763)
                     /gene="secE"
                     /locus_tag="VUX16_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET8124947.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            complement(773..925)
                     /gene="rpmG"
                     /locus_tag="VUX16_002059"
     CDS             complement(773..925)
                     /gene="rpmG"
                     /locus_tag="VUX16_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET8124948.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            complement(978..3173)
                     /locus_tag="VUX16_002060"
     CDS             complement(978..3173)
                     /locus_tag="VUX16_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET8124949.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            3299..4135
                     /locus_tag="VUX16_002061"
     CDS             3299..4135
                     /locus_tag="VUX16_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET8124950.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQYLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVSQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            complement(4203..5210)
                     /gene="gap"
                     /locus_tag="VUX16_002062"
     CDS             complement(4203..5210)
                     /gene="gap"
                     /locus_tag="VUX16_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET8124951.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(5387..6352)
                     /locus_tag="VUX16_002063"
     CDS             complement(5387..6352)
                     /locus_tag="VUX16_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET8124952.1"
                     /translation="MNMSNITIEDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDK
                     VLAGSLYTDTNEQGLTIPSSLLKNWNEQTGRNLTANDLIGKSVSASIVESAAEASKIA
                     QFQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVT
                     EELQKNKKYTVLSQQKVLDIVIIFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQR
                     SKEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSI
                     TKVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            complement(6413..>6853)
                     /locus_tag="VUX16_002064"
     CDS             complement(6413..>6853)
                     /locus_tag="VUX16_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET8124953.1"
                     /translation="ETGFDTYFYREYGRSLKGQLIRGKVSGRRYQRISLVAGLTNGEL
                     IAPMTYEETMTSDFFEAWFQNFLLPTLTTPSVIIMDNVRFHRMGKLELLCEEFGHKLL
                     PLPPYSPEYNPIEKTWAHIKKNLKKVLPSCNTFYEALFSCSCFN"
BASE COUNT         2051 a         1477 c         1189 g         2136 t
ORIGIN      
        1 attctgcgat ttggtttagg tttacttctg caactgtgtc attaccaaac atagagataa
       61 tcattttcac tttgttatta tcaatttctg taatcttacc agtgtagtct gcaaaagcac
      121 catcaataat acgtacagtt tgaccaatct caacatcgaa atcaaattct tgaacagttt
      181 gtcccataga taccaaaatg tcacgaattt cttgttccaa taatggagtt ggttttgatc
      241 tgttcccgtg tgatccgaca aatcctgtaa catttggtgt gtttcgaaca acaaaccaag
      301 cttcatctgt catgaccatt tctacaagaa cataacctgg aaaacgattt tcttctactt
      361 cttttctctt tccatttttt tcaacttgca ctgtttgtgt tggaatttca acgcgtagaa
      421 tattatccaa catattgtag gtttgtgcac gttgtaatag attttctttc accttatttt
      481 cataaccaga ataagtttgt aaaacaaacc accctttatc aaaactatcc atgatatttc
      541 ctttcataaa tagaagattt ctagtgtaat taactccact aatcttctaa aaaatgttaa
      601 taaatcgaat caaacctgaa acaatcaact ggtcaaaaat gtaaataatt actacaaaga
      661 aagctgtgta ttccatgata gaacgaaaat ctctccagct ttccttgcga gttggccatg
      721 ttgtgtcttt aagaagtcta aaaatatctc caataaaacg catcgctctc tcctatctcg
      781 tttctctgtg tgtagtgtac ttgccacaat gcttacaaaa tttatttact tctagtcgtg
      841 taggcttggg gtttccgctg atcttgattg aatagtttct cgaaccacaa accgcacaag
      901 ctaggcttgc tttttttagt gccataacgc ctccatctta tccattataa caagaaagct
      961 aggctttgac aagcatctta gcgaaataga ttgactatcg aatcccatat tgtttgagcc
     1021 ttttccttaa tcttcgcatc tgagatagcc cggctagcct catctactag actttgcgca
     1081 cgccctcgaa tatcagacaa attatcatct gtctggctat tatcattggt ttgtacttgt
     1141 ctttttgtat tggctggtgc aattccattt tgcttataag cattttcaac cgtaaaggta
     1201 cttcctggcg tataaggtaa aatggtattg gcaatgtttc taaagacatg agctgcaccg
     1261 tttgaagtag agccagctag atagtgattt tcatcagtgg tcggaaagcc aagccagtgg
     1321 ctaatcacta catccggagt ataaccaatt acccactggt cacttgtgta ctccggatta
     1381 aaaactgctt cagttgttcc agtcttccct gccataatat agtctgcagg cgatgaacta
     1441 ataccggtac cgttggtgaa agtccccaac atcatactgg tcatcttgtc agctacagac
     1501 ttatcaatca cccgtttttg tgaattttta tgattcgcaa taacttgtcc actagcattt
     1561 tcaattctac taataaaatg agcttcaggc attaaacctt catttgcaaa ggcagcgtat
     1621 gcttgagcca tttgaagagg gttggtttca acaccgcttc ccaaggcgac accaagaaca
     1681 cggtcgacct tttccatgtt gagtccgaat ttttcgcctg cctcaaaagc cttgtcgaca
     1741 cccaaatcat taacagtggc aacagcaggt agattaagcg attctgccaa ggcttgatac
     1801 ataggaactt ctcgactcgt tttgatccct gcatagttat caaccttata gctgtcatac
     1861 tgcatggtat ggttatccaa ctgcttattc aaagcccagc ctgcttcaac tgctggcgta
     1921 taaacaacta aaggcttaat tgtagaacca ggactacgct ttgattgggt tgcatagttg
     1981 aaattccgga atccagtttt atcattgtca gcaacttgac cgacaactcc acgaactccc
     2041 cctgttttcg gttcgagagc tacacttcct gattgagcaa acgttccatc ctctgccctc
     2101 ggaaatagcg atgtgttttc ataaacaatc tgcatatttg cttggtagtt ttggtccagc
     2161 tctgtgtaaa tgcggtagcc attattgaca atctcttcct ctgttagatt atacttggaa
     2221 acagcttcat taaccaccgc atcaaaataa gaggggtaac ggtaatctga gatttttcct
     2281 tcatacttat cgtgcaattg cgaagtcata tcaacttcag cagcttcggt ttcttggttt
     2341 ttatcaatat atcctgctgc aaccatattc tgcaagacag tatcgcgccg attagtagaa
     2401 tcttctacgg aattcaaggg attatacagt tccggcccct tgagcatccc tgccagagtc
     2461 gcagcttgat ccagactcac ttctgatgca gaaactccaa agtatttctt actcgcatct
     2521 tctacacccc acacaccatt tccaaaataa gcgttgttaa ggtacatggt tagaatttgc
     2581 tccttactat attttttgct taattctaag gcaaggaaaa attctttcgc ttttctctca
     2641 acagtttgat cttgtgataa ataggcgttt ttagccagct gttgggtaat ggtagagcca
     2701 ccacctgaac gtccagcagt gacaatagcc aagaagaaac ggccatagtt aatcccgtca
     2761 tttttataga aagaacggtc ttctgtcgca ataacagcat tctgcaagtt tttactgata
     2821 tcagtcagct caacataggt tcccttttga ccagacaagg caccagcctc tttttcttca
     2881 cgatcaaaaa taagagtccg agttttcaag gcattttgca aatcattgac attggtcgac
     2941 ttagctacag caaacaaata gattccaact agcaagcctg cactcaaacc tagtataagg
     3001 ataatctttg ttagatgata acgacgccag aattttcgaa tcggacctac ttgggctaat
     3061 ttttttcgat cactacgaga gcgacgtaag atagtagaat cagagtcctc tagttcactt
     3121 gtttcttttt taaaaagaga aagaaatttc tcaaataatt tatctaattt catgcgttta
     3181 ttttatcatc ttcatcatag gaagacaaga atttagctat ttcctatcca aatagggctt
     3241 tttttgttac aatatctgta tgcaattcac atttacatta cccgcctctc tacctcaaat
     3301 gacggtaaag caattacttg aggaacaact cctcatccct agaaaaatcc gtcatttttt
     3361 gagaatcaag aaacatattt tgataaatca agaagaagtc cactggaacg aaatcgtaaa
     3421 tcctggagat gtttgccagt tgacttttga cgaggaagat tatccccaaa agacgatccc
     3481 ttggggcaac ccagacttag tgcaggaagt ttatcaagat caatacttga ttattgtaaa
     3541 caaaccagag gggatgaaaa cgcatggtaa tcaaccaaac gaaattgccc ttcttaacca
     3601 tgtcagtacc tatgttagcc aaacctgcta tgtcgttcat cgtctggaca tggaaaccag
     3661 tggcttagtt ctctttgcca aaaatccttt tatcctgccc attctcaatc gcttattgga
     3721 gaaaaaagag atttctagag aatattgggc tctagttgat ggaaatatca acagaaaaga
     3781 acttgttttc agagacaaaa ttggacgtga tcgccatgat cgtagaaaaa gaatagttga
     3841 tgcaaaaaat gggcaatatg ctgaaacgca tgtaagcaga ttaaagcaat tctcaaacaa
     3901 gacttccttg gctcattgca agctaaagac agggcgaacc catcagattc gtgtgcacct
     3961 tttgcatcat aatcttccta tcctgggaga ccctctctat aatagtaaat caaagacaag
     4021 ccggcttatg cttcatgcct tccgactttc ctttacccac ccacttactt tagagaagct
     4081 aactttcact accctttcaa atacatttga aaaagaatta aaaaagaatg gatgatcgtg
     4141 tcatccattt ttccgtataa aaaaacaaga ccacaaagcc ttgctttcta tcaactcaag
     4201 aattatttag caatttttgc gaagtattca agagtacgaa caagttgtgc agtgtatgac
     4261 atttcgttgt cgtaccatga tacaacttta accaattgtt taccgtcaac gtcaagaact
     4321 ttagtttgag ttgcgtcaaa caatgaaccg taagacatac ctacgatatc tgaagatacg
     4381 attggatctt ctgtgtaacc gtatgattcg tttgaagctg ctttcatagc tgcgttcact
     4441 tcatcaacag taacgttctt ttcaagaact gctaccaatt cagtaactga tccagttgga
     4501 gttggaacgc gttgtgcaga tccgtcaagt ttaccattca attctgggat tacaagaccg
     4561 atagcttttg cagcaccagt tgagttagga acgatgtttg cagcaccagc gcgagcacgg
     4621 cgaaggtcac caccacggtg tggtccgtca aggatcattt ggtcaccagt gtaagcgtgg
     4681 atagtagtca tcaatccttc aacaacacca aagttgtctt gaagagcttt agccattgga
     4741 gccaagcagt ttgtagtaca tgaagcacct gagataactg tttcagtacc gtcaagaacg
     4801 tcgtggttag tgttgaatac aactgtttta acgtcgtttc caccaggagc agtgataaca
     4861 acttttttag ctccaccttt aaggtgtttt tcagctgctt ctttcttagc aaagaaacca
     4921 gtagcttcaa gaacgatttc tacaccgtca gtagcccagt cgatttgttc tggatcacgt
     4981 tcagcagaaa ctttgatgaa tttaccgtta acttcaaatc caccttcttt aacttcaaca
     5041 gtaccgtcga aacgaccttg agttgtgtcg tatttcaaca agtgtgcaag cataactgga
     5101 tctgtaaggt cgttgatgcg tgtaacttca acaccttcta cgttttggat acgacggaaa
     5161 gcaagacgac cgatacgtcc gaaaccgtta ataccaactt taactaccat tagtgatttc
     5221 ctccttatga aaatcatgaa atttttattg tgaaaagagt aacttgaatc actacaaatc
     5281 acctttcaac aaacctatta tacaactatt tgagttgaat tgcaagtatg gccattgttt
     5341 ttctatgtta gtttcttttt aagactgtaa atcaaggaat cccttactat tcatagcgta
     5401 acgattctac aggatccatt ttactaatct tacgcgccgg gaagtaggct gagacataac
     5461 caagtaatag agcgaaaact agagttccta aaacagataa aagatttaat tcaaaaacct
     5521 tagtgatgga tgggtaaaag tgacttacaa tcgcattcgc caaacttccc accccttgtg
     5581 caaccaaaaa tgccagcagc aaggcgatgc ctacaatcca gatagcctcg taaataaaaa
     5641 ttcctttgac atcacgattc tgataaccaa ctgctttcat gacacctatt tccttggaac
     5701 gttgcatgat attgatgtaa ataatgatac caatcataac cgctgctacc acaatagctt
     5761 gtgatgaaag cacaatcaat aatccctgaa taacacgaat aaagataatc acaatatcaa
     5821 gaactttttg ttgagaaagc acagtatact tcttattttt ctgtaattct tctgttacta
     5881 cttttgtctg tgatggatct ttgagttcca agataaaata agatacagct ttcgtaaatc
     5941 cagcctcttt caaaatcgtt tccatttgat gagacagcat gaaactgttg ctgtcctcca
     6001 tgtcatcttc atcattgatt acacgtacaa tcttcgtttg aaattgagca atcttactag
     6061 cttcggcagc actttctaca atgctggctg agactgattt accaataaga tcattagctg
     6121 tcaaatttct tcctgtctgt tcattccaat tttttagtaa actgcttgga atcgttaatc
     6181 cctgttcatt tgtatcagta tagagggatc cagccaacac tttgtccgtc tcattattac
     6241 taacagagat acttgtatca tcataaagac tcactacttg agcataagaa ggcatcgttt
     6301 gactcagatc catttcttgc ccatcttcta tagtaatatt tgacatgttc atcccaaaag
     6361 gactctccaa ataattaata gcttctttcc caactgtatc cgtgaactat agtcaattga
     6421 aacaagaaca agagaaaaga gcctcgtaaa aggtattgca acttggtaat acctttttga
     6481 ggttcttttt gatatgagcc catgttttct caataggatt gtactcaggt gagtagggag
     6541 gaagaggtaa aagtttatgc ccaaactctt cgcataaaag ttctagcttc cccattctat
     6601 ggaatcttac attatccata ataataaccg atggtgtggt taatgttggt aagagaaaat
     6661 tctgaaacca agcttcaaaa aagtcgctcg tcatcgtctc ttcgtaagtc attggagcga
     6721 ttaattcacc atttgttaga cctgcaacca aagaaatcct ctgatatctt cttccagata
     6781 ctttgcctct tattaactga ccttttaatg agcgaccata ttctcgataa aaataagtat
     6841 cgaatcctgt ttc
//
LOCUS       DAVDZK010000070         6251 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVDZK010000070 DAVDZK010000000
VERSION     DAVDZK010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6251
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.071"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..430
                     /gene="ply"
                     /locus_tag="VUX16_002065"
     CDS             <1..430
                     /gene="ply"
                     /locus_tag="VUX16_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET8124954.1"
                     /translation="SYTTSFLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVA
                     QYYITWDELSYDHQGKEVLTPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGL
                     AWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKVEND"
     gene            440..1186
                     /locus_tag="VUX16_002066"
     CDS             440..1186
                     /locus_tag="VUX16_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HET8124955.1"
                     /translation="MFATKRVKGDLFSGLITDVDEEIMNSDQNRLDIDTIVIHHNGGL
                     SDEGARSTWYVSTGHGTSAHYQVTPDKIWGCVGEESVAYHAGNYEVNQRSIGIEHLNN
                     RGEPDWTIAEETYWNSARLIADICNRYNLPINGEAIHPHREFTATDCPGGIDLNRLIR
                     MAAEILAGDSFQVSKEEQPRDGDGERLVRVVEDDLYIRTGPGLAYPDQGFCPLGTFTI
                     MQVEEADGYTWGLLKSGRGWIALDYTEEIK"
     gene            1202..1417
                     /locus_tag="VUX16_002067"
     CDS             1202..1417
                     /locus_tag="VUX16_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398183.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET8124956.1"
                     /translation="MKQKHKEDHKGEKVFRYSIRKYHFGAASVAVAALMFFANGTVQA
                     QTPEISPATESGTTRTSAFVSDSSGGV"
     gene            1623..4178
                     /locus_tag="VUX16_002068"
     CDS             1623..4178
                     /locus_tag="VUX16_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET8124957.1"
                     /translation="MLANLTLDSMKELHARVEAGLAGAKAVLENPHASQEEVNAQVRT
                     MRELTEEVNKALTGELTSPAELGEGRSVTLSEPSPTPRRGRGRRGPLTPPTAPVSTES
                     QEKKETVEEATDYTNGPGSYPLLENIHKLFQELKTSTGNPEQVQKLKEAYDKLNEALQ
                     TKEDGLVDQEVFNAALEEYKKAKHLKKGAEEDGKTRSRRSVSGLVYGFATGSTGKEIR
                     SKNDSGRERDTRNLYNGQNLNEIPLKYIATVETGTIRDISLSGFPTVGKDGKTWATIR
                     TRIDNGGKRAVLTITGQSPKDLYGIYNTILTVTEGNGHVSSKTQEVLYQLPKPEFDES
                     PLHPGKTAQQDVEGKAGDKPIVKGKIPTPPDGLKNSNIPKGTQIRMYLVRGGRNETFG
                     GIETSAEGYEIVAWGLVGGDGTSVIYPTQYKKQSIGDKPLRLIVAYVEPGTERISNRD
                     LVSPLSRDSITPTNPIDRDGAKSDADQKANAKKQSFDGIAHLTTEERNKANKQVDAAL
                     EKAKQAIDAANNQRDIETAKTTLEQDLGQISPTAEANKSAKSDADQKANLTLALIDDN
                     ENLSLFEKDAAKNQVRQALQDALKRIDQAKTQAEIDQAKQAALSSMDQVLAEALARAN
                     ARRLSGTRNRRTPPRRARRSVGFVGNSQTGTTPSAVDKSELRTLVEDLERRLKELEGL
                     SPEALEEAQRILREAQAALANDSLTAQELAELLAKVRQALNSIQVGTSADKSPSESNS
                     NKEAESAKEPTNATDVPLYGVFGAAVLSLLGALLFALAHKKNSQLDKLSRELDQLLVE
                     LEASDKDKKGLGKAKKLAKKARTFVDSQQKDPQKEAELISEIKTILSQFKEGV"
     gene            complement(4276..4644)
                     /locus_tag="VUX16_002069"
     CDS             complement(4276..4644)
                     /locus_tag="VUX16_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET8124958.1"
                     /translation="MDYKVGFTEQARQDLDDIFIYYSTEFSENIAKKVITRLQQITNL
                     LTFSPEGGINFDHKIGYSLYPGNTLRMIVSKQYLLFYLIHKKEVHILRIINSRTDYLN
                     QLDHLFRNRPITKYIEKSPD"
     gene            complement(4634..4921)
                     /locus_tag="VUX16_002070"
     CDS             complement(4634..4921)
                     /locus_tag="VUX16_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET8124959.1"
                     /translation="MSTLTRDRVYNFRVNTQLFEEAKTILESKNISLSDALNLFVEQI
                     VLEKGLPIKTADQLKAEVFLGELKAELDKGYQDIIEGRLYDADEVFSQYGL"
     gene            5406..5711
                     /locus_tag="VUX16_002071"
                     /pseudo
     CDS             5406..5711
                     /locus_tag="VUX16_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520543.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
     gene            5708..5992
                     /locus_tag="VUX16_002072"
                     /pseudo
     CDS             5708..5992
                     /locus_tag="VUX16_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
BASE COUNT         2031 a         1117 c         1462 g         1641 t
ORIGIN      
        1 ttcctataca acttcatttt tacgtgacaa tgtagttgcg acctttcaaa acagtacaga
       61 ctatgttgag actaaggtga cagcttacag aaacggagat ttactgctgg atcatagtgg
      121 tgcctatgtt gcccaatatt atattacttg ggatgaatta tcctatgatc atcaaggtaa
      181 ggaagtcttg actcctaagg cttgggacag aaatgggcag gatttgacgg ctcactttac
      241 cactagtatt cctttaaaag ggaatgttcg taatctctct gtcaaaatta gagagtgtac
      301 cggacttgcc tgggaatggt ggcgtacggt ttatgaaaaa accgatttgc cactagtgcg
      361 taagcggacg atttctattt ggggaacgac tctctatcct caggtagagg ataaggtaga
      421 aaatgactag gagggaagaa tgtttgcgac aaaaagagta aagggcgatt tgttttcagg
      481 actcatcaca gatgtggatg aggaaatcat gaatagcgat cagaatcgcc ttgatattga
      541 tactattgtc atccaccata atggtgggct gagtgatgaa ggggctagaa gtacttggta
      601 tgtctccaca gggcatggca catctgctca ctatcaggtg actcctgata agatatgggg
      661 gtgtgttggc gaagagagcg ttgcctatca tgccggcaac tatgaagtca atcagcgttc
      721 gattggtatt gaacatttaa ataaccgtgg agaaccggac tggacgattg cagaggaaac
      781 ctactggaac tcagcacgtt tgattgcaga tatttgtaat cgttataatt taccaatcaa
      841 tggggaggcc atccatcctc acagggaatt tactgctaca gattgtcctg gtgggattga
      901 tctaaatcgg ctcatccgga tggcagctga aattcttgct ggagatagtt tccaagtctc
      961 aaaagaggaa cagcctcgag atggggatgg agagcgccta gtgcgtgtgg tggaggatga
     1021 cctctacatc cgaacaggcc caggcctggc ttatcctgac caaggttttt gccctcttgg
     1081 gacttttacc atcatgcagg tagaagaagc agatggctat acttggggct tgctgaagtc
     1141 tggcaggggc tggatcgcac tagactatac agaagaaatc aaatagaaaa aggaagaaag
     1201 aatgaaacaa aagcataaag aggatcataa aggggaaaag gtttttcgtt attcgataag
     1261 gaagtaccac ttcggtgctg ctagtgttgc cgttgcggcg ctgatgtttt ttgccaacgg
     1321 gacagtacag gcacaaacgc ctgagatttc cccagcgaca gagagtggaa cgactagaac
     1381 cagtgccttt gtaagcgatt cctcgggggg tgtctagaga gctaagtgaa gaaagtcctg
     1441 tcacagcccc tagtgaaccc gagcaatcta gccaaggcaa tcaaaagcct caagaggcat
     1501 cagatgaaaa ccagtctcta gtaaaaacta acgaagaagg caagaaggaa agccaagcag
     1561 agacaagtca tcctactgta gataagtcac ttgccgagtc tgcacaaagt agcctgcaag
     1621 ccttgcttgc caatctgaca ctggactcta tgaaagaact tcacgctcgt gtagaagcag
     1681 gtctagcagg agctaaagct gttcttgaaa atccacatgc tagtcaagag gaggtcaatg
     1741 cccaggttcg aaccatgagg gaattgactg aagaagtcaa caaggctttg actggtgagc
     1801 tcacatcccc agctgagctt ggagaaggaa ggagtgtgac tctgagcgaa ccaagcccga
     1861 ctcctagacg ggggcgaggt cgcagggggc cgctaacccc tcctacagca ccagtgtcaa
     1921 cagaaagtca agaaaagaag gaaacagtgg aggaggctac ggactacaca aatggtccag
     1981 gtagctaccc tctattagaa aacatccata aactcttcca agaactgaag accagcactg
     2041 gaaatccaga acaagtccaa aaactgaaag aggcttacga taaactcaat gaagcattac
     2101 agactaagga agatggactt gttgaccagg aggtttttaa tgccgccctt gaggagtata
     2161 aaaaggctaa gcacctaaaa aaaggtgcgg aggaagatgg aaaaactagg agtcgtagaa
     2221 gtgtttctgg actggtctat gggtttgcta caggaagtac cgggaaggaa ataagatcta
     2281 agaatgattc aggaagagaa agagacactc gtaatttata taacggtcaa aacttaaacg
     2341 agataccttt aaaatatatt gctactgtag aaactggaac tattagagat atttctttat
     2401 cagggttccc aacagtgggt aaggacggta aaacttgggc tacaatcaga acgagaattg
     2461 ataatggtgg aaagagagct gttttaacta ttaccggcca gtctcctaaa gatctctatg
     2521 ggatatacaa tacaatctta acagtaactg aaggaaacgg tcacgtgtct agtaagactc
     2581 aagaggttct gtatcaacta ccaaaaccag aatttgatga atctccacta catccaggaa
     2641 agactgctca acaagatgta gagggaaaag caggagacaa acctatagtt aaggggaaaa
     2701 ttcctactcc accagatgga ttaaagaatt cgaatattcc gaaaggcacc caaataagaa
     2761 tgtatctggt ccgaggtgga cgtaatgaaa ctttcggtgg aattgaaact tcagcagaag
     2821 gttatgagat cgttgcctgg gggttagtgg gaggagatgg aacatcagta atatatccga
     2881 ctcaatacaa gaaacaatcc ataggtgata aaccactacg tcttattgta gcttatgttg
     2941 aaccagggac agaacgaata tcaaatagag atttagtttc acctctttct agggattcca
     3001 ttacgccgac caatccgatt gatagggatg gggctaaatc agacgcagat caaaaagcga
     3061 atgcgaagaa acaaagcttt gatggcattg cacatctgac aaccgaagag cgcaacaaag
     3121 cgaataaaca agttgacgca gcacttgaaa aagctaaaca agcaattgat gcggcaaata
     3181 accaacgcga tattgagact gctaaaacaa cgcttgagca agatttaggt caaatctctc
     3241 cgacagcaga ggcgaacaag tcagctaaat cagacgcaga tcaaaaagcg aatcttaccc
     3301 ttgctcttat tgatgacaat gaaaaccttt ctctatttga aaaagatgct gctaaaaatc
     3361 aggtaaggca ggctcttcaa gatgctctta agagaattga tcaagccaaa acacaagctg
     3421 aaatcgatca agccaagcaa gcagctttat ctagcatgga tcaggtttta gccgaggctc
     3481 tggctagagc taatgcgcga agactgtctg gtacaagaaa tcgaagaact cctccacgcc
     3541 gcgctcgtag aagcgttgga tttgtaggga attcccaaac aggtacaact ccatcggctg
     3601 tggacaagtc tgaacttcgt actttggtag aggatctgga acgccgcttg aaagagttag
     3661 aaggtctatc tcctgaagca cttgaggaag cacagcgtat cttgagagag gcgcaagcag
     3721 ctcttgctaa tgactcctta acagctcaag aattagcgga actccttgcc aaagttagac
     3781 aggctcttaa ttctatacaa gttggcacat cagctgataa gagtccgtct gagtcaaact
     3841 caaataagga agcagaaagc gccaaggaac ctacaaatgc gacagatgtc cctctatatg
     3901 gtgtctttgg agctgcagtg ctctctcttc taggagctct cctctttgca ctggctcata
     3961 agaaaaactc tcagctagat aagctttcaa gagaattaga tcaacttcta gttgagttag
     4021 aggctagtga caaggataaa aaaggtttag gcaaggctaa aaaattagct aagaaagcaa
     4081 gaacctttgt ggatagccag caaaaagatc ctcaaaaaga agcagaacta atttctgaaa
     4141 tcaagactat tctcagtcaa ttcaaagaag gagtctagtc ttgaagaaaa cttactttca
     4201 aaaacgaagt gagtaggttt gtagcgatga tgaggaaata aaaaatctcc agattaggaa
     4261 ccatcagtga gttctctagt ctggagattt ttcaatatat ttcgttattg gacggttacg
     4321 aaagaggtgg tcgagttggt ttaggtagtc ggtgcgtgag ttgataattc tcaggatatg
     4381 gacttctttt ttgtgaatga ggtaaaagag taggtattgt ttagagacaa tcattctgag
     4441 agtgtttcct ggatagaggg agtatccgat tttatggtca aagttaatac cgccctctgg
     4501 tgagaaggtg agtaggttgg taatttgttg gaggcgagtg atgactttct tggctatgtt
     4561 ttcactgaac tctgtggagt agtagatgaa aatatcgtcc aagtcttgtc tggcttgttc
     4621 tgtgaagcct actttatagt ccatactgtg aaaagacctc gtctgcgtcg tagagacgcc
     4681 cctcgatgat gtcttggtag cctttatcta gttctgcttt aagttcgcct aggaagactt
     4741 ctgcttttag ttggtcagct gttttaattg ggagaccttt ttcaaggacg atttgttcta
     4801 caaagaggtt gagggcatct gaaaggctga tgtttttgct ttctaggatg gtttttgctt
     4861 cttcaaatag ttgagtattg acgcggaagt tataaactcg gtctcgtgta agtgttgaca
     4921 tggcatttct ccttgtaatg atattgtagt acatatatat tacaaaaaaa tatagagaaa
     4981 gtcaagggtt gttttagtag gtgtgattcg aatgtgataa tgtctttagt aaatcgaacg
     5041 tgaaaatgtc ccatttggta gaatagtcat atgaaaagaa tccaactgaa tatgaatgaa
     5101 acgaaaaaat atcttgtgat aaaagttata gcccaaggaa agaaaacaaa gaaacgagcc
     5161 tgtgtcgaac ttaatctttc tgaaagacat tcaataaagc agtaggttct tgaaacctct
     5221 aagagctagg attacgatag tgttttatgg ttaatagttt tctgtgtcac tgctttttta
     5281 tcggataggc taatctaatc tttcaacagt gtaatagtgg tatttcgatt tcagaaagca
     5341 tttaattgac aagtaatgca aattgatgta aaattacagt acaaatctta agtgaggtga
     5401 taagaatggg aaaaacagct acaattagtg ttcgagttga taaattagat aaacaatcag
     5461 ctgaataggt tttgaagcag cttgggatgc cgatatcaac attagttaca ctattattga
     5521 aacaagtatc attaacgaag aaaatccctt ttgatattgc attgccagat gtgccttcat
     5581 cagtgaatgt agaggaaatg acagctgaac gatttggaca aatgatgatt gaagcttatc
     5641 atgaagcaga aaacggtcat gttcgatctg tcaatgagtt ctttaaagaa tttaaagaac
     5701 ggaacgtatg actaaaataa ccattaatat tttaaaaaga gctgaaggag atatggaagc
     5761 catttatcat tatatcgcag atgagcttca atcgccggaa actgctatga ataactttga
     5821 agctattgta gaggaattgc tcagtttaga tattaaagtt agatgactac tagcaagaaa
     5881 ttattcagtg ttttatcgtt ttgataagga tacagttccc atcttgagag tgttacatca
     5941 atcaagtagc ttggacagat tactgtttga aatcgggaac aaatccgatt gacatatacg
     6001 tatttagtca gattatattc tatttgatgg cacttatata tagtagattg aatctaaaat
     6061 agtacactga gactgctaaa aatatttcta gaaagttaga ttgactttcc taatcgattt
     6121 gctcatacct tatttcaatc tactataaaa tcataatgaa agctttttaa gaaacatgga
     6181 aaaaactgtt cattgtgctc cagatgctaa agcttaatct agctgaacaa tacagataga
     6241 acctgcccat t
//
LOCUS       DAVDZK010000071         6093 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVDZK010000071 DAVDZK010000000
VERSION     DAVDZK010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6093
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.072"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(661..1545)
                     /locus_tag="VUX16_002073"
     CDS             complement(661..1545)
                     /locus_tag="VUX16_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET8124960.1"
                     /translation="MMEKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKQIKECL
                     HQMILDQEQIQEIILSLWENSVVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(1549..1935)
                     /locus_tag="VUX16_002074"
     CDS             complement(1549..1935)
                     /locus_tag="VUX16_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET8124961.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEV"
     gene            complement(1928..3271)
                     /locus_tag="VUX16_002075"
     CDS             complement(1928..3271)
                     /locus_tag="VUX16_002075"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET8124962.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNIKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWSNSGNYDASVKQALADMLEVFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(3353..4237)
                     /locus_tag="VUX16_002076"
     CDS             complement(3353..4237)
                     /locus_tag="VUX16_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124963.1"
                     /translation="MIQVRNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRLYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPKRGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(4249..4866)
                     /gene="cysE"
                     /locus_tag="VUX16_002077"
     CDS             complement(4249..4866)
                     /gene="cysE"
                     /locus_tag="VUX16_002077"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET8124964.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(4882..>6093)
                     /gene="pnp"
                     /locus_tag="VUX16_002078"
     CDS             complement(4882..>6093)
                     /gene="pnp"
                     /locus_tag="VUX16_002078"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET8124965.1"
                     /translation="DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKR
                     FMHHYNFPQYSVGETGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLE
                     SNGSSSQASICAGTLALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDM
                     DFKVAGTRDGITALQMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELA
                     PTAPKIDTIKIDVDKIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINR
                     AKEIIAGLVREAKVDEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDL
                     VEIGDEVDVKVIKIDEKGRIDASMKALLPRSPKPEHDEKGEKSERPHRPRHQKDHKPK
                     KEFTETPKDSE"
BASE COUNT         1750 a         1444 c         1142 g         1757 t
ORIGIN      
        1 atccttctcc tccttctatt ataccatagt tttaaatcta attttgctag attctatggt
       61 tctatctatt tattcgaaaa agaaaggaga aagttaaaaa tttttagact tcacaggttg
      121 aaatttacat aaaaaagcag ctgattcttt ttttgattct accatatttc tagcgattac
      181 tcctataaat aggatacatc acagtttcta gtaaaaaagg acgctgaaaa gcaaacaaaa
      241 cccagtatta ggaagagtta aatcttatct gaaaatgact agctctcaag ctatagtttt
      301 gtgtctaaat ataagtatca ctaggaaaaa ctccgtaagt aaacacaccg aaattggatg
      361 ttcctactat gcgaaaacct ctttaaacta cgtcaacttt accttaccta cagcttcaaa
      421 aggacgtttt gagtcatctg ctggtcgatt tattcattga ttttcaatct tctaatacta
      481 aacaaaaatc aaacaactat agtgaaataa cataaaattt acatgaatag attagggaaa
      541 tcaaagcaag ttctaggaat gttttagcag tcaccgtata ctttcccagc ctcaatccac
      601 tataactcta cacataaaaa tggagaagat ggccatcctc ttctccaaat attaacttct
      661 ttacaaacca actatagttg acaaagaacc taaaatcaat tgataacaca aggtcaggtc
      721 ggtcaactct ttcaactgaa gccctgtcaa ctcttcccat ttatcaatct tgtattggag
      781 agaattgcgg tgcagatata gttgctgggc tgttttagtg agaacaacac tattttccca
      841 aagagagaga atgatttcct gaatctgttc ttgatccaaa atcatctggt gtagacattc
      901 cttgatttgc ttcaagtcca cgagtctttc tcccatactc caaagataga gctgagaaaa
      961 agtatgaaca ccttggtgac cctgacgcca ccatgtcttg aacaaatccc gctcagcttt
     1021 gattaagtct gatagggctt gatgccccgt ctgagaccaa acctgaccca acatgataga
     1081 aagacgaagt ccaaagtcat actcaaccgc ttcaatcgta tcacttaaaa tatctcttac
     1141 agaagtgtat ttgtcttgtt gaagcacgaa aacataatcc tgagctccga cctgtagcac
     1201 tgtctgacaa ttcggaaaaa gagtccgcat catatctagc caagaagcca gattttcctg
     1261 ctgaaaataa gaaagatggc aataaactaa ctgaatcttt ttaaaaactt gcggtgcctg
     1321 tcccttgcct tcaaccagat aggaatacca agggtttagc gaacgagcct gctcctgctg
     1381 ggtcaaaagg gcaaccaact gcttttcacg ctcgctgagc ccagcttcct ccagcaaaat
     1441 ccactgctga gaagctaaag ggagcgtgag atagccctct ttctctactg gttggtctga
     1501 aatccgagcc tcaggaaacc agtcttgtag ttctttttcc atcatgtcct agacctccac
     1561 tttttggatg caccatgaaa ccaaactctc aagacgttcc agattctcag tcatatggag
     1621 ataacccatg actgcttcaa aacctgtgga catacgataa gtcaccacat ctgcattttt
     1681 agcctttgtg tgactattag tattgcggcc acgtttgtag atttcttctt ctttttccgt
     1741 tagaacctgc tcctccaaca tgagagcaat caggcgagcc tgagccttgg ctgacacata
     1801 cttggttgct tcttgatgga gtttattggg tttggtcata cctttgagga tgaggtgacg
     1861 gcgaatatac atagaataca ccgcatcccc ctcaaaggct agcgcaatcc cgttaatgag
     1921 attgacatca atcacgtgtc cacctcactc catccttggt atcaaggagc ttaattcctt
     1981 gagtaaccaa ttggtcacgg atttggtctg ctgtcgcaaa gtcacgattg gcacgcgcct
     2041 cttggcgttt ttgaatcaag tcttcaatct ctgcatccaa aacttcctca acaaagacaa
     2101 ttccaaaaac ttctaacata tccgcaagag cttgcttgac acttgcatca tagttccctg
     2161 agttgctcca tttggccatt tcaaagacaa ctgtgatacc gttggcagca ttaaaatctt
     2221 catccatagc tgctacaaac ttatctttaa agttttgtaa ctcttgggca tccacatttc
     2281 ctgtaaatgg ttgttcgtaa gtattcttca gatacttgag attggtctcg gcatcgcgaa
     2341 ctgccttttc cgtgaagttg ataggcttac ggtagtgctg ggtcgcaaag aagaaacgaa
     2401 gtacttgccc atcaagagtt ttaagggcat cgtgtaccgt aatgaagtta cccaaggact
     2461 tagacatttt gatattgtcg atattgacaa agccattgtg catccagtag ttagcaaaag
     2521 ccttgcctgt tttagcttca gactgggcaa tttcattggt gtggtgtgga aactctaggt
     2581 cagctccacc accgtggata tcaatggtat cacctaaaat ctctgtcgac atgactgaac
     2641 actcaatatg ccaacccgga cgtccaggtc cccaaggact atcccaagaa atctcacctg
     2701 gtttggaaga tttccataga gcaaaatcta caggattttc cttacgagcc gtttcttcat
     2761 cggtacgacc tgaagcacct agatccaaat cttccaaggt tttattagct aatttagcat
     2821 agttgtggga tttttctaca cggaaataga catccccttg actctcatag gcaaagcctt
     2881 tctcgatcaa gtcttccaca aaacggatga tgtctgccat aaactccact acacgcggat
     2941 ggcgagtcgc aggtttcacg cctaaggccg tcacatcctc acgaaaggca gcgatgtact
     3001 tatccgcaac ctcctgaggc gtgatacctt cttccctggc acggttgata atcttatcat
     3061 ccacatctgt aaaattggaa atataggcaa ccttataccc acggtactca aaatagcgac
     3121 gaatcgtatc aaaagctacc gtcgaacggg cgtttcccac gtggatatag ttgtacaccg
     3181 ttggcccaca aacatacatc ttgatcttgc cgtcctcaat cgggacaaat tctcgcaaat
     3241 cacgagacat ggtgtcatag attttaatca taaatcataa tcaagaaagc tgaaatccaa
     3301 gaacaattag tttcatcact aaaagttcaa gtaaatttca gtccgaatat ctctacactt
     3361 cggaatccct tgctcctttc tcattcagat aaaccacctg agtctgtttg acaaagccaa
     3421 ttttttcata caaacgtttg gcacctacat tgctatcttc cactgcaatc tgaaattcct
     3481 tgtcattttg ctcaattagt tggttgacga gggattttgc taagtagctt ccatagcctt
     3541 tcccacgttt aggttccgat attgctaaac cgtagaagta attcgtatta gtcgataaat
     3601 ctaccgtgca agtcccaata acctgaccgt cttttaacaa aatatatagt cggctttctg
     3661 gatccttcag agcttcagcg acatatctat ccacaacttc tctcgattca tgttcctctg
     3721 aaaatgcctg aaattttaat tgactaattt gatcctgata cgaactatct gctaacaaaa
     3781 cttcaagatg ggaaacattt gctaacggat aaagtcttct atccttacct aaccaagttt
     3841 ctgtctcttc atcctcgatt agtccccagt tactggcaaa gtcaggatga ttctctaaaa
     3901 aaatacgttc tgtctgaaaa gtgactgatc gaatggggaa agaagctgtt tctctctcaa
     3961 aactagtaaa caatgcacgc gcaatcccct gacggcgatg acctggatga accagtatcg
     4021 tcacttctac atcttggtca tctgcataga cagttaataa accaacaagt tcgccttttt
     4081 cataataaag gaaaaaggcg ggcatgtttg ggtcaaaatt aagcatgtta gagagatagg
     4141 gatcgcgata ggtaccgtca tagttttggc aacagttaat tacttttttc gcctcagata
     4201 gctcctcttg gcttaacttg tttcttactt gaatcatata ggtatcctct acaaaccaga
     4261 cgatctgtga ctggcatctt tagcctgctc gagtttattg acataatact ctcgtttttc
     4321 ttcgacttcg tgaatgacag gctcatcttt cttaccatga agacggacaa tcttggccgg
     4381 aataccgaca accgtcacat cactaggtac atctgctacg acaactgctg cagcaccgac
     4441 cttggcattt tcaccaattt ccacaggtcc gataacttgg gcatgggctg atatgagggc
     4501 tccctttcgt acagtcggat ggcgtttgcc acagtctttc cctgttcccc caagagtcac
     4561 tccgtgatag agaagaacgc ctttttcaac aatcgctgtc tctccaatca ccagaccaga
     4621 accatggtca ataaagacac ctgaatcaat ctgggctcct ggatgaatct caatctgagt
     4681 ccaaaagcgc caaaactgac tgtgcatacg agctaagagt ttgaagccgt gcttccagag
     4741 aaaatgcgag agacggtggg ccgccaaggc cttgacacct ggataagtca gcaaaacctc
     4801 caaagtggtg cgggccgctg gatcattttc ttttacgata tcaatggttt cgcgccacca
     4861 ccccatacat ttctcctttt cttattctga atcttttggt gtttctgtaa attctttctt
     4921 aggtttgtga tccttttgat gacgtgggcg gtgagggcgc tcagactttt cacctttttc
     4981 atcatgctca ggttttggcg aacgaggtag aagagccttc atagaggcat cgatacggcc
     5041 tttttcatca atcttgataa ccttaacatc aacttcatcc ccgatttcta ccaaatcctc
     5101 tacacgattg gtacgagtcc aagccatctc agagatatga acaagggcat ctgtcttatc
     5161 aaagaggtta acaaaggcac caaatttctc gatacgaacg actttagcac ggtaaacttc
     5221 atccactttg gcttcacgaa ccaaaccagc aataatttct ttggcacggt taatagcatc
     5281 ttggtcacta gagtagatag acacatttcc ttcttcgtct atatcaatct taacacctgt
     5341 ttcagcgata atcttgtcga tggtttctcc acccttaccg atgacaatct taatcttgtc
     5401 cacatcaatc ttgatcgtat caattttcgg agcagttgga gccaattctg gacgaacttc
     5461 tggaatggtt gcttcaatga catcaaggat ttcaaaacgc gctttcttgg cttgagcaag
     5521 agcctccgtc aagatttctg cagtaatccc ttgaatcttg atatccattt gaagggctgt
     5581 aatcccatca cgagtacctg caaccttgaa gtccatatct ccaaagtgat cttccaaacc
     5641 ttggatatct gtcaatactg tgtagttatt tccatctgag ataagtccca tagcaatacc
     5701 agctactggc gccttgattg gcacaccacc agccataagg gcaagagttc ccgcacagat
     5761 agaagcttga gatgaagaac cgtttgattc caaaacttct gctactagac ggatagcgta
     5821 tgggaattct tccaagcttg gtaagacttg agcaagagca cgctcaccaa gagcaccgtg
     5881 accgatttca cgacgacctg gcgcaccgta acgacctgtt tcccctacag aatattgagg
     5941 gaagttatag tggtgcataa agcgtttctt gtactctgga tccaaaccat caatgatttg
     6001 agtttctccc atcggagcca aggtcaagac tgaaagagct tgagtttgcc cacgagtaaa
     6061 gagacctgaa ccatgtacac gaggaaggaa gtc
//
LOCUS       DAVDZK010000072         6002 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVDZK010000072 DAVDZK010000000
VERSION     DAVDZK010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.073"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(431..811)
                     /locus_tag="VUX16_002079"
     CDS             complement(431..811)
                     /locus_tag="VUX16_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HET8124966.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            complement(957..2309)
                     /locus_tag="VUX16_002080"
     CDS             complement(957..2309)
                     /locus_tag="VUX16_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HET8124967.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLVKLRAKEAIFEKFEQSLNEKYNRMSNSGEEQEYYGKVEYYLSQLNSENYNN
                     STQYSKIQDEYTKLNKITAERNQLDADLQTLQNELIQLQQQGDSPSLSDTTSADDKAK
                     LETKILEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLVSEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILAPNEGTLHYLVPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKADVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVVLQKDMPVEVRIVYDKETYLDWILEMLSFKQ
                     "
     gene            complement(2306..2773)
                     /locus_tag="VUX16_002081"
     CDS             complement(2306..2773)
                     /locus_tag="VUX16_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET8124968.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(2766..4985)
                     /locus_tag="VUX16_002082"
     CDS             complement(2766..4985)
                     /locus_tag="VUX16_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HET8124969.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYGFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDITLSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIMDKTTIVVAHRLSTILR
                     CDKICFLENGTIVEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDTEEVTYG"
     gene            5451..>6002
                     /locus_tag="VUX16_002083"
     CDS             5451..>6002
                     /locus_tag="VUX16_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8124970.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQR"
BASE COUNT         1964 a         1200 c          826 g         2012 t
ORIGIN      
        1 ccagaagttt ttagctctgc caagccacat agtgtgttta ctactatgtg tccatgtcac
       61 catgaatcgc cgaacgattt aacgagaaag tatgactttt acgtttatcc caactcaatt
      121 atgacatttt tttcaaaagt caatatatct cactttttca acgacaagaa agaggctgat
      181 aatctaccaa cctcttgttt ttaaatacat ttcaagtcca aactattctt tatagaaaaa
      241 agtcctataa attcgagcaa tagttaaaat acaaacaaat ataattccca aaatagataa
      301 cactattttc acaaaattca tttcagaacc tattatatat acgtgaaaaa aaggggctat
      361 tcctacacat atatacaata aataacttac aaagtttatt tcaccaattc ctgcaaaaaa
      421 atgtttcatt ttaagcaaaa atataaccat ctaagctacc gtcagcccaa tcagccccat
      481 atgcgattgc tccacctagt gaaaatccag taacagttag tgcaacgttt agtgcagtat
      541 tgactaaatg gccagctgca ctacctacat gtttaattat taaactacgt aatgttctcg
      601 taatagcccc tctattagct gagatagctt tttttatcgc ataagcagaa taaattgttg
      661 caccaccact atagatggcc aaacctacat ccagaactgt tgcaaaacta cctctactat
      721 tccaccagtt acgaccaaca ccacccccat caagatacat catctcttct tgctcaagag
      781 caacataatt atttggtaat acgagttcca tttattttct ccttttttat taagcatggt
      841 taggatagtt tcctaacaag tgagcatcga ctttgtttat agcacttagt tacctagata
      901 agatatcttc cctttatctt actttatttt ataggtgact taatgtttaa aaccaattat
      961 tgcttgaaac ttaacatttc caaaatccaa tcaagatagg tttctttatc atagacaatc
     1021 cgcacttcaa ctggcatatc cttttggagg acgactgtct cacttccatg ttttagagtt
     1081 aaggtttcta attctatcat gactttataa agactaatat tgccttcttt cgtttcttgg
     1141 gaaattgttc ctgaatcaat ctgtctgact tgtcccttta gtgttccata tttttgacta
     1201 tttacaccag taatagcaac atcagctttt gctcctttcg aaacacgaga aatatcactc
     1261 gcaagtacaa aagcttctac atagtaacct ttttctttcc ctgaaacttc tgctatcgtt
     1321 tgcccctgct gaatagacat tccttgtttc aaaggtacca aataatgcag agtaccttca
     1381 tttggcgcta atatactatg agctttatct tgacctgttg ccactccaag attagcctca
     1441 agctctgtaa tacttttatt gttgtttgaa cgagcagtac ctaactcact aactaattga
     1501 gcataaatat tataagcctg agaagttgga tcattatagg tacggttcat atctttaata
     1561 ttgctttgtt gactatcaat ctcgctattc ttagaagtaa tatttgtttt taatgcttcg
     1621 atttttgttg ttatttctaa tatcttagtt tctaacttag ctttatcatc agctgatgtc
     1681 gtatctgata aggaagggga gtctccttgc tgttgaagtt gaatcaattc attttgtaga
     1741 gtttgcaagt cggcatctaa ctgatttctt tcagctgtta ttttattcaa cttcgtatat
     1801 tcatcctgaa tctttgaata ctgggtacta ttattataat tttccgaatt taactgagat
     1861 aggtagtatt caactttccc ataatattcc tgttcttcac cagaattaga catacggttg
     1921 tatttctcat ttaatgattg ttcaaatttt tcaaagatag cttcttttgc acgtaacttc
     1981 accaattgtt tatttaaaga gctcgcttgt aaaccttctt gtccacttga taacgaaata
     2041 atgacatctc cagcatttac catatctcct tctgacttat gtaaagtaac taccttccct
     2101 gaaccaattg ctgataggaa ctctgtacct gttataactg aatttccatt cgcttttaca
     2161 atatagtttt tgggtatata agctgcgcca accaatgcac cgcttaagat aatagcagtt
     2221 gaaataatga gaataaacgc aaaagctggt ggtctcttat caaagaaaat acgagaataa
     2281 cgtaattctg atttattata taatttcata ggcttacaat tggtctaaaa atatctacta
     2341 ccattttttc aggagaagaa ttaacataaa ctgtatagac aatcccatcc gtttgaatat
     2401 cattttcata gacatataga tccaatttag aatacgcata ctgtagatac tctggactgt
     2461 cttcaaaacg aacatataaa caatatggaa cagagataga atcctgtaca tcataaatgt
     2521 tactgtactg ttgagcatta tgagcttgaa tataaaactc aaaatcagtc gttattaatc
     2581 catcatcatg aatagtagta ccacaacttt ttacaattaa tggaccaaaa atttgtgctt
     2641 ttaacaactg caaatgttga tgaaatttat taatttcctg atctacatct tctacttttg
     2701 tatcatgtaa ctttttacag ataactgact ttagtaccag ttttttatta tcttttacct
     2761 ctaacttagc cataagtaac ctcctctgta tctaacacag cctgtgactg aatttgttga
     2821 ttcacttgaa cgctctgcaa accaaccatt ctagcatact ttccattttt cgccattagt
     2881 tcttcatgag tcccatattc cacaatagtc ccattttcta aaaagcatat cttatcacat
     2941 cgaagaattg tagacagcct gtgggctact acaattgttg tcttatccat tattttatta
     3001 aagattaaat cctgaataat ctgttcacta aatgaatcta agttagaggt tgcctcatca
     3061 aatatataca aatcagcttt actcagtagt gctcttgcaa tagccaatcg ttgtttctct
     3121 ccacccgaga aattttgacc gccttcttct acaaaggagc cataacgatt ttgaagacgt
     3181 tgaatcgtat catgaatacc aacaatacga caaactctca ccatatcctc atatgtaaca
     3241 gaaggattac caatttttag attatcaata attgtccctg taaagagttc tatggtctga
     3301 ggaatgtagg aaattttctt acgtagttta ccatagtcaa gatctgataa gtcattttct
     3361 cctatacgaa ttttcccctc actcggattt ataaatctta ataacaaacg aactagcgta
     3421 ctttttcctg ctccgctttc tccaacaaaa gctatttttt ctccttgttt aattcgcaaa
     3481 ttaaagtcct tgataacagg agggcgtgaa ccataggcaa atgttacatc tttaaattca
     3541 atgtcatcac ataaggtgaa gtctctaata ctataatcca aggcaatgtc ttcacgatct
     3601 acttccatca attcttgaag ccgactaacc gcaacctgta cctcttgaaa ggttaactgc
     3661 aagccaacta aattctgaat aggttctgta aaatattgac ttaatgtctg aaaaaccaag
     3721 aggtccccaa tagtcatttt tccatcaatg ataaataagg cgcccactcc cataaataat
     3781 aacccaccca tggttgaggt cattgaagat attgtagatt gaatattctg caaaacaccc
     3841 tctttataac caatttctaa agtgtgaaca aatttttctt caattttgtt taaacgttgt
     3901 tcctcatcat gctgagactt aatggtatca atgttacgaa tagattcaat taactgtgaa
     3961 ttaagaagtc catttgcttc catttgttca tgattaattt ttttataagg ctttttaaaa
     4021 cagtatataa gaatgatgtt aacaataacc ataaaaacta atatcagaaa taaagattga
     4081 ttaatagtcc aaaggacaac cgcactaata actgacaagg tgatatccat gactaatgaa
     4141 atagagactg acgtaaacac attctttatc gtcatcgcat cttgaaatct tgttaaaaca
     4201 tcaccaactc tacgacttcc aaaaaaacca taaggaagat gaataatatg gtcataatat
     4261 cccattaaaa ccggtatatc aatttttcga gatagaaaca aaagaacgtg ctgacgaaat
     4321 gcagatagaa gagtctgtaa gaacgatact attccaaata ctatcaaaaa catatacaga
     4381 ctatttttta aagcatatgg aatcacctcg tccatgataa cttttgaaaa gagactcgat
     4441 aaaataccaa tgatacttaa aacaaaggaa gctaatatga ctgtactaat caatcctttt
     4501 tgattaaaaa ttaaccttcc aaataaatca agaagtcctt ttccctttag tttccctctt
     4561 tcaaaatccg aatttggaac cataaaaaga gtaatacctt gataaatttc tcccagttcg
     4621 tcacttgaca tcttgcgtat gccactagca gggtctgcta cgtaaaattt actattcctt
     4681 ttgatactat gtaataccac aaaatgattt tgacctaaat cattcttaac ttgaagaatc
     4741 gcaggaaatg ttaattttgg agtcaaatct tccagtgcta ctcgaacagc ttttactgta
     4801 aaattcaact tattcagacc tgaaacaata ccactgacag tcgttccata catgtctgta
     4861 ccaataattt ccctaatctt catgattgat agttcctttt tgtaagataa aagaactgtt
     4921 gaaacaactg ccgcagcaca atctgactgg tcatgttgca tcgtacaagg atattttttt
     4981 aacatagaaa tactcaattc tttagaattc atctaacttt tctttgatgt cacccaaacc
     5041 tcaatcactg cccagtagtt cttgaatcag tttattttca atcgtatcat tctttgttct
     5101 tgatatcttt ccaagcattg tagtacagca gatttttgtc caaggactaa gcctccttta
     5161 acaactcaag ctcccttaca ttatatcgac cagccccatg gaaagattat ggccagacta
     5221 atcaatgata taatacatac tagaatacaa aatatttttt tattcatact ttttctccta
     5281 tctttatttt ctacctacac catacctctt attaagctca ttttaaaatt acgttaactt
     5341 ttttcacaaa tttatttcga ctttcttttt tactttttac attgctatga tacaatattt
     5401 ttaacaaaat tttattgttt gttaactttt ttcacgaaaa ggagaaaatc atgcgttatg
     5461 atttcggaaa ggtctataaa gaaatacgtg agtcaaaggg gctgacccaa gaagaggtct
     5521 gtgggggtgt tctctcaaga accagcttat caaaaatcga aagtggcaag acaaccccaa
     5581 aatatgaaaa tatggaattt cttctccgtc aaatcaatat gagttttgaa gagtttgaat
     5641 atatctgtca actttatcaa ccaagtcaac gcacagagat tatgcaaacc tatctcaata
     5701 tgcgttccat tatcgggacc agcgatcttg tcaatttatt tcaaaaatgc caagactacc
     5761 tcaagaccca ccacgatctc cctatagaag aaatcagaga tatgcttgaa gttgttattt
     5821 atctccgtca acacggggca ggggaactat caaaacacgc agaacaggtt gtcaaaaaac
     5881 tttggaaaaa aattgaaaaa caagatacat ggtatgagag tgatctaaaa atcctcaata
     5941 ccattctttt cagttttccc attgaatacc tccatctcat cactggaaaa atcttgcaac
     6001 gc
//
LOCUS       DAVDZK010000073         5472 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVDZK010000073 DAVDZK010000000
VERSION     DAVDZK010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.074"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..>5472
                     /locus_tag="VUX16_002084"
     CDS             <1..>5472
                     /locus_tag="VUX16_002084"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124971.1"
                     /translation="DSSKVSTRQPLELKSVDELKGQEAPVEENNQVQAAAESETTGVE
                     SNSAQPETNPASQEAPQAEGEGKQDQSTHVSNQTSSTSLLQPRTLKNKQSDYDSIPLG
                     DDEDDEDDVRNGLFSSENPVTTIQPRSPRSVTSRSVPPKTTGSSPYNDKYRYYFERGQ
                     DPENSQLPRYTYAFFNEKVIFGLEEATKVSHIKDYLKEEIKPTTDGFSWKVTVNQARQ
                     NLNGISFLFSVPNGQSLVPNSVTVTQVDDAGTTVKSSDPGDRNDDHITASLKATNANA
                     VMKGTPTRTNASGGDGFVGSTGHYDVSSIDRIWNEANLPDKDSFHSRGQGNNNNARTG
                     LQNDEERKLGDSKKMIINSSGGTVYSGKIAGNTSYTITFKTRGSNDLDKLAYFSAVKG
                     SNGGKTYLAMLLHARTQGERDFADKIRFRLKGNGYYQVEQNTAYYTSTVLNSTGQEIK
                     KDGANTAYSYSKYKDKPLDNGVKGVLTGNDTNDTDKAFDLDEYSYSEYVDDQGQVLNK
                     DDLSAQLEEQQQTITWYKGGQQISKSDLTKDAISSSGVHTYRYRVSYKDNSFNEGEIH
                     FVTKPKKPEITTDIETKLGQTLDVTVRNIEPNSEVTLYRKGANNQAGSLIGTVAANNQ
                     GNQVTFSGVNLQAGTYYVKQKAAGSWLDRSNRRVEGVYSDPSSDKKVDGLRVGTTGKI
                     IQYDTIDRKPINQQLVRDNPRNAALDHAFIAESPDGIKTVDVQNPDNLPGFTTNEPSN
                     ASSPTRKGINVHVPAGNMQGTYRLVFEVVSNSGTRKTFTTIINYPPVAPSFETTSEKL
                     KGKAQETLKTAQPPIIINAKGVSVSNNKVQTGKKWKVFLVRGGFNNNNNIVPKAEGYE
                     IIAEALPRDGDKRAIFTPDKFKVDKLGTQPLRLITALVDEKTGKVDENVVSTLSESSI
                     QATNPITQYQIRPEVQQDPDTLEVTAKVGQGTANKAKVTYFHQGLVPVSEIFTKVGNS
                     WVKDSQNNNNITVSNNSDGTAIIHIPYGLNTKNTPIAASQHEEGQSLWSENNSVIPKG
                     DETAPKVSLGDAVLPTTENDATTPIYKVVQGSAFAPKLKVWDNIGSVKELDITDIPAG
                     ITKQKFGTTFQSQDNAKEANKYSGSTFSGNVADTQAVGQYTAQITVKDASNNTATYYL
                     RYEVLPKVEARQAKFPQVKSKALQDGENPETYIQFKNNTQNVSKPSVADVTWERQPST
                     ATEGLDKTGVVKVTYHVTDENGVARDEVKTVTINTPVYHATVNNGGVYTTTVGTNFSA
                     STSATGGYVNSNFKPNVKYYWKSNRENNYPEYGGDTRSQTADYLGKRQDTIRVFYPNS
                     QDVQDYQDKRSEDHVITFISKPRIPSVDAASLAGKANQENQTVIVSNVTPGTTVKLYN
                     GDTEIGSVNVPKGDNESYTTVKNNVTVTVNGTLPLSDNIRAKTIYTPDNVDSGYSTSV
                     SSTTQAPSKPSISQSPEDLVVKAKVGQDGATKVTLTYINANGVAKTVGFTKNHGNWDK
                     DNANADATVSITNETDGLGEIQLQQDTAQAGSEVTVKQKTDTSDYSPSATIKALSRLE
                     DLRNVAQADGAVDIHVPEDATRMSLTYTPTGQATPTTLEYTKNGRTWTAHNGINTYSD
                     ERKISIPKGVVEDGTTVSVIASNDSKTTTNVKSKAKFEQPSEITNTIRQNGDVEVTLP
                     TNAEEVTLSYKNKQNVMSTVTVSKSQGNTWTVGNLPDGVSFRDGKVTFDYRKVNRDTP
                     ITISATRGTGEEKSQQRTKTISIPEHEVEVTKITKKAGESTTNEELLAAIDVAKKKSA
                     VLKKGTQYPTTVGNYDLEVMVTYADDSTEIVRVPYEVTAV"
BASE COUNT         2032 a          981 c         1144 g         1315 t
ORIGIN      
        1 agactcgagc aaggtttcaa ctcgccagcc acttgaactc aaatcggtcg acgagttgaa
       61 agggcaagaa gcgccagttg aggaaaataa tcaagtacaa gcagccgctg agtctgaaac
      121 gactggagta gaatccaact ctgctcagcc agagacaaat ccagctagtc aagaagctcc
      181 tcaagcagag ggagaaggaa aacaagacca gtcgactcat gtttccaacc aaacaagcag
      241 caccagcctc ctccagccgc ggacgctcaa aaacaagcag tctgactatg actctattcc
      301 acttggcgat gatgaggatg atgaggatga cgtaagaaat gggctgtttt cttcggaaaa
      361 tccagtaacc actatccaac cacggagccc tcgctctgta accagtcgct cagttccgcc
      421 gaaaacaact ggttctagcc cttataacga taagtatcgc tactatttcg aacgtggaca
      481 ggatccagaa aacagccaac ttccacgcta tacctacgct ttctttaatg aaaaagtcat
      541 attcggtctt gaagaggcga ctaaggtttc ccacattaag gattatttaa aggaagaaat
      601 taaaccgact acagatggat ttagctggaa agttactgta aaccaagcga gacaaaactt
      661 aaatggaatc agctttctct tttccgtgcc taatggacaa agtcttgttc caaatagcgt
      721 cactgtgaca caggtagatg atgcagggac tacagttaaa agttcggatc ctggggatag
      781 aaacgatgat cacattacag cttctttgaa agctactaat gctaatgcag taatgaaagg
      841 gactcctacc agaacaaatg caagtggtgg agacggattt gttggatcaa ctgggcatta
      901 tgacgtttct tcaattgata gaatttggaa tgaggcaaat cttccagaca aagactcctt
      961 ccactctcga gggcagggaa ataataacaa tgctaggaca ggtttacaga acgatgaaga
     1021 acgtaagctt ggagactcta aaaaaatgat tattaattcc tcaggaggaa cagtctactc
     1081 tggaaaaatt gctggaaata ccagctatac aatcaccttt aagactagag ggtcaaatga
     1141 cctggacaag ttggcttact tttctgctgt aaaaggtagt aatgggggta agacctatct
     1201 agctatgttg ctgcatgcta gaacgcaagg tgaacgcgat tttgctgata agattcgctt
     1261 ccgcctcaag ggcaatggtt actatcaagt ggagcaaaac acagcctatt acaccagcac
     1321 ggtattgaat agcactggtc aggaaattaa gaaagacggt gccaatacag cttactcata
     1381 ctctaaatat aaggataaac ctcttgataa tggagtcaaa ggagtattga ccggcaatga
     1441 tacaaatgat acagataaag cttttgactt ggatgaatat tcttatagtg agtacgttga
     1501 tgaccaaggt caagttttaa acaaagatga tttgtcagcg cagctagaag aacagcagca
     1561 aacgattacc tggtataagg gtggtcaaca aatcagtaaa tctgatttga caaaagatgc
     1621 tatttctagc tctggggttc atacctacag gtatcgcgtt tcctataagg acaattcttt
     1681 taatgaagga gaaatccatt ttgtaacaaa acctaaaaag cctgaaataa caacagatat
     1741 agaaacaaaa ttagggcaaa cacttgatgt tacagtgaga aatatcgaac caaatagtga
     1801 ggtgacatta tatagaaaag gtgcaaataa tcaagctggt tcacttatag gtacagttgc
     1861 agctaacaat caaggaaatc aagttacatt ctcaggagtc aatcttcaag ccgggactta
     1921 ctatgtgaaa caaaaagcgg caggaagctg gttagaccgt tcaaatagaa gggttgaagg
     1981 agtttattct gatccctctt ctgataaaaa agtagatgga ctaagagtgg gaactactgg
     2041 taaaattatt caatatgata caatcgatag aaaaccaata aaccaacagt tagtaagaga
     2101 caacccaaga aatgctgctt tagaccacgc ttttatagca gagtctccag atggaattaa
     2161 aactgtagac gtgcagaatc cagataactt acctggattc actacaaacg aaccgtctaa
     2221 cgcatctagc cccactagaa aagggataaa tgtacacgtg ccggcaggaa atatgcaggg
     2281 tacttataga cttgtatttg aagtagtatc taatagtggt acaaggaaaa catttaccac
     2341 gattattaac tatccaccag ttgccccatc ttttgaaaca acatcagaaa aattgaaagg
     2401 gaaagctcaa gagactctaa aaacagccca gccgcctatc attataaatg caaaaggtgt
     2461 gagtgttagt aataataagg tgcaaactgg caaaaaatgg aaagtctttt tggttagagg
     2521 tggattcaat aataataata atattgttcc taaagcagaa ggttatgaaa ttatcgctga
     2581 agcactacca agagatggag ataaaagagc catattcaca cctgataaat ttaaggtgga
     2641 taaattagga actcaaccac ttcgacttat aactgcattg gtagatgaaa agacaggaaa
     2701 agtagatgaa aacgtagttt ctactttgag tgagagtagt atacaagcaa ctaatccaat
     2761 aacacaatac caaataagac cggaagtaca gcaagatcca gatactttag aagttactgc
     2821 caaagttgga caaggtacgg ctaataaggc gaaagttact tatttccatc aaggattagt
     2881 tcctgttagc gaaatattca ctaaagtagg aaattcatgg gtcaaagatt cacaaaacaa
     2941 taacaatata actgtttcga ataattcaga tggaacagcg ataatccata ttccatacgg
     3001 gttgaataca aaaaacacgc caattgcagc tagtcaacat gaagaaggac aaagtctatg
     3061 gtcagaaaat aatagtgtaa tcccaaaagg agatgaaacg gcaccgaagg tgagtttagg
     3121 agatgctgtt cttccaacta ctgaaaatga tgctacaact ccgatataca aggttgtaca
     3181 aggaagtgca tttgcaccga aacttaaggt ttgggataat ataggtagtg tcaaggagtt
     3241 ggatataaca gatatccctg ctggaattac taagcaaaaa ttcggaacta cattccaaag
     3301 tcaagataat gctaaggaag cgaataaata tagtggttca acatttagtg gtaatgttgc
     3361 agatacacaa gcagtaggac aatatacagc tcaaattact gtaaaagatg catcaaataa
     3421 tacagctact tactacttgc gttatgaggt tcttccaaaa gtagaagcta ggcaagctaa
     3481 gtttcctcaa gttaaaagta aagcattaca agatggagaa aatccagaaa cttatattca
     3541 atttaaaaat aatactcaaa atgtcagcaa accatcagta gcagatgtaa cttgggaaag
     3601 acaaccaagt acagcaactg aaggtcttga taaaacagga gtagtaaaag ttacctacca
     3661 tgtgacagat gaaaacggtg tagcccgaga tgaagttaaa actgtgacaa ttaatacgcc
     3721 agtctatcac gcaactgtga ataatggtgg tgtttataca acaacagtag gaactaactt
     3781 ctcagcttct accagtgcaa ctggaggata tgtaaattct aactttaaac ctaatgttaa
     3841 atattattgg aaatcaaaca gagagaataa ttatcctgaa tatggaggag atacacgtag
     3901 ccaaacagca gattatctag gaaaacgtca ggatacaatt cgagttttct atccaaattc
     3961 ccaagatgtt caggattatc aagataaacg ttcagaagac catgtgatta cgtttatttc
     4021 taaaccgcgt attccgtctg tcgatgcagc gtcactagct ggaaaagcga atcaggaaaa
     4081 ccaaacagta atagtaagta atgttacacc aggaacaact gttaaattat acaatggcga
     4141 tactgagatt ggttcagtaa atgtaccgaa aggtgataat gagtcttata caactgtcaa
     4201 aaataatgtt acggtaacgg taaatggtac attaccactt tctgacaata ttcgtgcaaa
     4261 aacgatatac acacctgata atgtagactc gggatatagc acgagtgtaa gcagtacgac
     4321 gcaggcacca tcgaaaccaa gcatctctca aagtccagaa gatttagtag tgaaagcgaa
     4381 agtagggcaa gatggagcta caaaagtgac gcttacctat attaatgcaa atggagttgc
     4441 taaaacagta ggatttacga aaaaccatgg aaactgggat aaagataatg cgaatgctga
     4501 tgctacagta tcgattacaa atgagactga tggtctaggt gaaattcaac ttcaacaaga
     4561 tacagcacaa gcaggttctg aagtgactgt taaacaaaaa acggacacat cagattacag
     4621 cccttcagca acaataaaag cgctaagtag attagaagat ctaagaaatg ttgctcaagc
     4681 agatggggct gtggatatcc atgttccgga agatgcgact cgtatgagtt taacttatac
     4741 accgacaggg caggctacgc cgacaacatt agaatacacg aaaaacggta gaacatggac
     4801 agctcataac ggaataaata cttattctga tgaacgtaaa atatccattc caaaaggtgt
     4861 tgtagaggat ggtactacag tttcggttat tgcatcaaac gatagtaaaa caactactaa
     4921 tgtaaaaagt aaagcgaagt ttgaacaacc tagtgaaata actaatacta tacgtcaaaa
     4981 cggagatgta gaggttacat taccaacaaa cgctgaagaa gttacattaa gctataaaaa
     5041 taaacaaaat gtaatgtcta cagtaacagt atctaagagc caaggtaata cttggacagt
     5101 aggaaactta ccagatggag taagcttcag ggatggtaag gttacatttg attatagaaa
     5161 agtaaataga gacactccta ttacaatatc cgctactaga ggaacaggag aggaaaaatc
     5221 acaacagaga acgaagacaa tctctatacc agagcatgaa gttgaagtga cgaaaatcac
     5281 gaaaaaagcg ggcgagtcaa cgacaaatga agaattactt gctgcgattg atgtagctaa
     5341 gaaaaaatcg gctgtattga aaaaaggaac gcaatatcca acaactgtag gaaattatga
     5401 tcttgaagtt atggtaactt atgcagacga cagtaccgag atagttaggg tgccttatga
     5461 agtaacggca gt
//
LOCUS       DAVDZK010000074         5176 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVDZK010000074 DAVDZK010000000
VERSION     DAVDZK010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.075"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            309..1854
                     /locus_tag="VUX16_002085"
     rRNA            309..1854
                     /locus_tag="VUX16_002085"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1906..1978
                     /locus_tag="VUX16_002086"
     tRNA            1906..1978
                     /locus_tag="VUX16_002086"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1939..1941,aa:Ala,seq:tgc)
     gene            2103..5004
                     /locus_tag="VUX16_002087"
     rRNA            2103..5004
                     /locus_tag="VUX16_002087"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5081..>5176
                     /gene="rrf"
                     /locus_tag="VUX16_002088"
     rRNA            5081..>5176
                     /gene="rrf"
                     /locus_tag="VUX16_002088"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1465 a         1050 c         1513 g         1148 t
ORIGIN      
        1 gggttaagac accgcctttt cacggcggta acacgggttc gaatcccgta cggactatgg
       61 tatgttgcgt caggaccact tgatgaaaaa aagtttaaaa aagcttaaaa atcttcaaaa
      121 aagtgttgac aagtgaaagt ggctgtgata tactaatata gttgtcgctt gagagaagca
      181 agtggcaaag acctttgaaa actgaacaag acgaaccaat gtgcagggcg ctacaacata
      241 agttgtagta ctgaacaatg aaaaaacaat aaatctgtca gtgacagaaa tgagtaagaa
      301 ctcaaacttt taatgagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcctaat
      361 acatgcaagt agaacgctga aggaggagct tgcttctctg gatgagttgc gaacgggtga
      421 gtaacgcgta ggtaacctgc ctggtagcgg gggataacta ttggaaacga tagctaatac
      481 cgcataagag tagatgttgc atgacatttg cttaaaaggt gcacttgcat cactaccaga
      541 tggacctgcg ttgtattagc tagttggtgg ggtaacggct caccaaggcg acgatacata
      601 gccgacctga gagggtgatc ggccacactg ggactgagac acggcccaga ctcctacggg
      661 aggcagcagt agggaatctt cggcaatgga cggaagtctg accgagcaac gccgcgtgag
      721 tgaagaaggt tttcggatcg taaagctctg ttgtaagaga agaacgagtg tgagagtgga
      781 aagttcacac tgtgacggta tcttaccaga aagggacggc taactacgtg ccagcagccg
      841 cggtaatacg taggtcccga gcgttgtccg gatttattgg gcgtaaagcg agcgcaggcg
      901 gttagataag tctgaagtta aaggctgtgg cttaaccata gtaggctttg gaaactgttt
      961 aacttgagtg caagagggga gagtggaatt ccatgtgtag cggtgaaatg cgtagatata
     1021 tggaggaaca ccagtggcga aagcggctct ctggcttgta actgacgctg aggctcgaaa
     1081 gcgtggggag caaacaggat tagataccct ggtagtccac gctgtaaacg atgagtgcta
     1141 ggtgttagac cctttccggg gtttagtgcc gtagctaacg cattaagcac tccgcctggg
     1201 gagtacgacc gcaaggttga aactcaaagg aattgacggg ggcccgcaca agcggtggag
     1261 catgtggttt aattcgaagc aacgcgaaga accttaccag gtcttgacat ccctctgacc
     1321 gctctagaga tagagctttc cttcgggaca gaggtgacag gtggtgcatg gttgtcgtca
     1381 gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccccta ttgttagttg
     1441 ccatcattta gttgggcact ctagcgagac tgccggtaat aaaccggagg aaggtgggga
     1501 tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac acgtgctaca atggctggta
     1561 caacgagtcg caagccggtg acggcaagct aatctcttaa agccagtctc agttcggatt
     1621 gtaggctgca actcgcctac atgaagtcgg aatcgctagt aatcgcggat cagcacgccg
     1681 cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccacgaga gtttgtaaca
     1741 cccgaagtcg gtgaggtaac cgtaaggagc cagccgccta aggtgggata gatgattggg
     1801 gtgaagtcgt aacaaggtag ccgtatcgga aggtgcggct ggatcacctc ctttctaagg
     1861 ataaggaact gcgcattggt cttgtttagt cttgagaggt cttgtggggc cttagctcag
     1921 ctgggagagc gcctgctttg cacgcaggag gtcagcggtt cgatcccgct aggctccatt
     1981 ggtgagagat caccaagtaa tgcacattga aaattgaata tctatatcaa atagtaacaa
     2041 gaaaataaac cgaaaacgct gtagtattaa taagagttta tgactgaaag gtcagaaaat
     2101 aaggttaagt taataagggc gcacggtgga tgccttggca ctaggagccg aagaaggacg
     2161 tgacaaacga cgatatgcct tgggtagctg taagtaagcg atgatccagg gatttccgaa
     2221 tgggggaacc caacaggtaa tacctgttac ccacatctgt taaggatgtg aggaggaaga
     2281 cgcagtgaac tgaaacatct aagtagctgc aggaagagaa agcaaaagcg attgccttag
     2341 tagcggcgag cgaaacggca ggagggcaaa ccgaagagtt tactcttcgg ggttgtagga
     2401 ctgcaatgtg gactcaaaga ttatagaaga atgatttggg aagatcagcc aaagagagta
     2461 atagcctcgt atttaaaata gtctttgtac ttagcagtat cctgagtacg gcgggacacg
     2521 tgaaatcccg tcggaatctg ggaggaccat ctcccaaccc taaatactcc ctagtgaccg
     2581 atagtgaacc agtaccgtga gggaaaggtg aaaagcaccc cgggagggga gtgaaataga
     2641 acctgaaacc gtgtgcctac aacaagttcg agcccgttaa tgggtgagag cgtgcctttt
     2701 gtagaatgaa ccggcgagtt acgttatgat gcgaggttaa gttgaagaga cggagccgta
     2761 gggaaaccga gtctgaatag ggcgccttag tatcatgacg tagacccgaa accatgtgac
     2821 ctacccatga gcaggttgaa ggtgcggtaa gacgcactgg aggaccgaac cagggcacgt
     2881 tgaaaagtgc ttggatgact tgtgggtagc ggagaaattc caaacgaact tggagatagc
     2941 tggttctctc cgaaatagct ttagggctag cgtcgacatt agagattctt ggaggtagag
     3001 cactgtttgg gtgaggggtc catcccggat taccaatctc agataaactc cgaatgccaa
     3061 tgaattatgg tcggcagtca gactgcgagt gctaagatcc gtagtcgaaa gggaaacagc
     3121 ccagaccacc agctaaggtc ccaaaataat tgttaagtgg aaaaggatgt ggggttgcac
     3181 agacaactag gatgttagct tagaagcagc tattcattca aagagtgcgt aatagctcac
     3241 tagtcgagtg accctgcgcc gaaaatgtac cggggctaaa acaatttacc gaagctgtgg
     3301 atacctttat aggtatggta ggagagcgtt ctatgtgtga tgaaggtata ccgtgaggag
     3361 tactggaacg catagaagtg agaatgccgg tatgagtagc gaaagacagg tgagaatcct
     3421 gtccaccgta agactaaggt ttccagggga aggctcgtcc gccctgggtt agtcgggacc
     3481 taaggagaga ccgaaaggtg tatccgatgg acaacaggtt gatattcctg tactagagta
     3541 tgtagtgatg gagggacgca gtaggctaac taaagcagac gattggaaga gtctgtctaa
     3601 gcagtgaggt gtgaattgag tcaaatgctt aattctataa cattgagctg tgatggggag
     3661 cgaagtttag tagcgaagtt agtgacgtca cactgccaag aaaagcttct agcgtttaaa
     3721 catactctac ccgtaccgca aaccgacaca ggtagtcgag gcgagtagcc tcaggtgagc
     3781 gagagaactc tcgttaagga actcggcaaa atgaccccgt aacttcggga gaaggggtgc
     3841 tgactttaag tcagccgcag tgaataggcc caagcaactg tttatcaaaa acacagctct
     3901 ctgctaaatc gtaagatgat gtataggggg tgacgcctgc ccggtgctgg aaggttaaga
     3961 ggagtgctta gcgtaagcga aggtatgaat tgaagcccca gtaaacggcg gccgtaacta
     4021 taacggtcct aaggtagcga aattccttgt cgggtaagtt ccgacccgca cgaaaggcgt
     4081 aatgatttgg gcactgtctc aacgagagac tcggtgaaat tttagtacct gtgaagatgc
     4141 aggttacccg cgacaggacg gaaagacccc atggagcttt actgcagttt gatattgagt
     4201 gtctgtacca catgtacagg ataggtagga gtctaagaga tcgggacacc agtttcgaag
     4261 gagacgctgt tgggatacta cccttgtgtt atggccactc taacccagat aggtgatccc
     4321 tatcggagac agtgtctgac gggcagtttg actggggcgg tcgcctccta aaaggtaacg
     4381 gaggcgccca aaggttccct cagaatggtt ggaaatcatt cgcagagtgt aaaggtataa
     4441 gggagcttga ctgcgagagc tacaactcga gcagggacga aagtcgggct tagtgatccg
     4501 gtggttccgt atggaagggc catcgctcaa cggataaaag ctaccctggg gataacaggc
     4561 ttatctcccc caagagttca catcgacggg gaggtttggc acctcgatgt cggctcgtcg
     4621 catcctgggg ctgtagtcgg tcccaagggt tgggctgttc gcccattaaa gcggcacgcg
     4681 agctgggttc agaacgtcgt gagacagttc ggtccctatc cgtcgcgggc gtaggaaatt
     4741 tgagaggatc tgctcctagt acgagaggac cagagtggac ttaccgctgg tgtaccagtt
     4801 gtcttgccaa aggcatcgct gggtagctat gtagggaagg gataaacgct gaaagcatct
     4861 aagtgtgaaa cccacctcaa gatgagattt cccatgatta tatatcagta agagccctga
     4921 gggatgatca ggtagatagg ttagaagtgg aagtgtggcg acacatgtag cggactaata
     4981 ctaatagctc gaggacttat ccaaagtaac tgagaatatg aaagcgaacg gttttcttga
     5041 attgaataga tattcaattt tgagtaggta ttactcagag ttaagtgacg atagcctagg
     5101 agatacacct gtacccatgc cgaacacaga agttaagccc tagaacgccg gaagtagttg
     5161 ggggttgccc cctgtg
//
LOCUS       DAVDZK010000075         5138 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVDZK010000075 DAVDZK010000000
VERSION     DAVDZK010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.076"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            7..297
                     /locus_tag="VUX16_002089"
     CDS             7..297
                     /locus_tag="VUX16_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET8124972.1"
                     /translation="MKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTEIVR
                     DHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            294..611
                     /locus_tag="VUX16_002090"
     CDS             294..611
                     /locus_tag="VUX16_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET8124973.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRDIYPALPEIEE
                     TNPEFTFIRMGRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            627..1253
                     /locus_tag="VUX16_002091"
     CDS             627..1253
                     /locus_tag="VUX16_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET8124974.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVACLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMIPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            1295..2056
                     /locus_tag="VUX16_002092"
     CDS             1295..2056
                     /locus_tag="VUX16_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HET8124975.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKA
                     EFAETFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTRQPRRVQITDMTIMANQQATGFMIHKK"
     gene            2134..2529
                     /locus_tag="VUX16_002093"
     CDS             2134..2529
                     /locus_tag="VUX16_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET8124976.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRPRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            2799..3083
                     /gene="groES"
                     /locus_tag="VUX16_002094"
     CDS             2799..3083
                     /gene="groES"
                     /locus_tag="VUX16_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET8124977.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            3099..4721
                     /gene="groL"
                     /locus_tag="VUX16_002095"
     CDS             3099..4721
                     /gene="groL"
                     /locus_tag="VUX16_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET8124978.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGSATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(4821..>5138)
                     /locus_tag="VUX16_002096"
     CDS             complement(4821..>5138)
                     /locus_tag="VUX16_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET8124979.1"
                     /translation="HLYQLLLFHFQNKEPEKFFGFIEDNLKQVHPLFQTIFKTFLKDK
                     EKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVL
                     SQA"
BASE COUNT         1563 a          949 c         1237 g         1389 t
ORIGIN      
        1 aatggtatga aagctaaaaa aatgtggatg gcaggcttgg ctctgctagg tatcggaagc
       61 cttgctcttg ctacgaaaaa agttgcagat gaccgtaagc tcatgaagac tcaggaagag
      121 ttgacagaga ttgtgcgaga ccatttttcc gacatggggg aaattgcgac cctttatgtt
      181 caagtttacg aaagcagtct ggagagcttg gttggtggcg tcatttttga ggatggccgt
      241 cattatacct ttgtctatga aaatgaagac ctagtctatg aggaggaagt cttatgatac
      301 agccagcaag tttagaagaa ttagcatctt tagtggaaaa agcgggcaag aaggtcttcc
      361 tttttgtggc agactggtgt ggcgattgtc gtgatattta tcctgcctta ccagagattg
      421 aggagaccaa tccagagttc acctttattc gaatgggccg agatcagtat atggatttgg
      481 ccaaactctg ggatgtttac ggaattccta gccttgttgt tctagaaaag gacaaggaaa
      541 tcggtcgttt tgtcaatcgc gaccgtaaaa gtaaggagca aattaacgat tttttagcag
      601 gattgaaata ggagaaaaag gaaacaatga tttttacata taacaaagaa catgtcggtg
      661 atgtccttat ggtcatcgtg aaaaatagcg gagatgccaa actgaatgtg gaacgcaaag
      721 gcaaggtagc ccgtgttttc ctcaaagaaa atggggaaac agtagcttgg aacatttttg
      781 aggtttcgag cttgtttgaa attgcagagc gaggtcaagt ctttttatca gatgagcaag
      841 tcgcttgttt gaaccaagaa ttacaggcgg aaggttttac agaagaaatt gtcaatgaca
      901 aggaacctaa gtttgttgtt ggtgaaattg ttgagatggt agcccatcca gatagtgacc
      961 acctcaacat ctgccaagtt gcagtcgcaa gtgataagac tgtacaaatt gttgcaggag
     1021 ctcccaatgc gcgtgtgggg ttgaaaacca ttgtcgcgct tcctggagct atgataccaa
     1081 aagggaatct cattttccca ggtgaacttc gtggtgaaaa gagttttggt atgatgtgca
     1141 gtcctcgtga attgcatctg ccaaatgctc cacaaaaacg tggggtgctt gaattatcag
     1201 aagaccaagt tgtcggaaca ccatttgact cagctaaaca ctggactgcc taagaagttg
     1261 ttaatatctg atagaccagc tagaaggaaa taagatggca aaaaatgttg tgattacagg
     1321 agcgacatca ggaatcggtg aagcgattgc gcgtgcttat ctagagcagg gtgaggatgt
     1381 cgttctaaca ggacgacgga tagacagact agaagctctt aaggcggagt ttgcagaaac
     1441 ttttccaaat caaacagttt ggacttttcc actagatgtg acggatatgg tcatggtgaa
     1501 gactgtttgc tctgatattc tagaaacgat agggaggatt gatatcttgg tcaacaacgc
     1561 cggactggct cttggcttag ctccctatca agactatgaa gagttggata tgctgaccat
     1621 gttggatacc aatgtcaaag gtttgatggc agtcactcgc tgtttcttgc cagcaatggt
     1681 aaaagccaat caaggtcata ttatcaatat ggggtcaacc gcaggaattt atgcctatgc
     1741 tggtgcagct gtttactcag ccaccaaggc ggcagttaag accttttcag atggactgcg
     1801 aattgatacc atcgcaacgg atatcaaggt gacaaccatt cagcctggga ttgtcgaaac
     1861 agatttctca actgttcgtt ttcatggtga taaagagcgg gctgcgtccg tttaccaagg
     1921 aatagaagcc ttgcaagctc aggatattgc agacacagta gtctatgtga ccagacagcc
     1981 tcgccgtgtt cagattacag atatgaccat tatggctaat caacaggcga caggtttcat
     2041 gattcataaa aaataagaaa tttcctcgaa aagttacaaa tttctgtaac tttttttgat
     2101 ttcctacgaa tagataagta ggaggaagaa aatatgtata ataaagttat catgattggg
     2161 cgtttaacgt ctacaccaga attgcacaaa accaacaatg acaagtcggt agcgcgagca
     2221 actatcgctg tcaaccgtcg ttacaaagac caaaacggtg aacgtgaagc tgattttgtc
     2281 aatatggtcc tatggggcag actagcagaa actttggcaa gctacgcaac caaaggtagt
     2341 ctcatttccg ttgatggaga attgcgtccc cgtcgctttg agaaaaatgg tcagatgaac
     2401 tatgtaaccg aagtccttgt gacaggattc caactcttag aaagtcgtgc tcaacgtgcc
     2461 atgcgtgaaa ataatgcagg ccaagatttg gcagatttgg tcttggaaga ggaagaattg
     2521 ccattttaat actcttcgaa aatctcttca aaccacgtta gctttatcca caacctcaaa
     2581 gcaatgcttt gagcaacctg cggctagctt cctagtttgc tctttgattt ttattgagta
     2641 taaacattaa aaagtctgag ttggtctcag gctttttatc ttgagaaagt cagacttttt
     2701 tcttgactat ttctgaccaa gtgatacaat agaattatga attagcactc aagttcaaag
     2761 agtgctaata atatctatct cattatggag gaaatcagat gttgaaacca ttaggggacc
     2821 gtgtggtctt aaaaatagaa gaaaaagaac aaaccgttgg gggctttgtc cttgcaggat
     2881 cagcccaaga aaaaaccaaa acagctcaag ttgtggctac tggacaaggt gttcgtacct
     2941 tgaacggtga cttggttgct ccaagtgtta aaactggaga tcgtgtctta gttgaagccc
     3001 acgcaggtct tgatgtcaaa gatggcgatg aaaagtacat catcgtaggc gaagctaaca
     3061 ttttggcaat cattgaggaa tagaaggaga aagtaagtat gtcaaaagaa attaaatttt
     3121 catcagatgc ccgttcagcc atggttcgtg gtgtcgatat ccttgcagac actgttaaag
     3181 taaccttggg accaaaaggt cgcaatgtcg ttcttgaaaa gtcattcggt tcacccttga
     3241 ttaccaatga cggtgtgacc attgccaaag aaatcgaatt ggaagaccat tttgaaaata
     3301 tgggtgctaa gttagtatca gaagtagctt ctaaaaccaa tgatatcgca ggtgacggga
     3361 ctacgactgc aacagtcttg acccaagcta tcgtccgtga aggaatcaaa aacgtcacag
     3421 caggtgcaaa tccaatcggt attcgtcgtg ggattgaaac agcagttgcc gcagcagttg
     3481 aagctttgaa aaacaacgcc atccctgttg ccaataaaga agctatcgct caagttgcag
     3541 ccgtatcttc tcgttctgaa aaagttggtg agtacatctc tgaagcaatg gaaaaagttg
     3601 gcaaagacgg tgtcatcacc atcgaagagt cacgtggtat ggaaacagag cttgaagtcg
     3661 tagaaggaat gcagtttgac cgtggttacc tttcacagta catggtgaca gatagcgaaa
     3721 aaatggtggc tgaccttgaa aatccgtaca ttttgattac agacaagaaa atttccaata
     3781 tccaagaaat cttgccactt ttggaaagca ttctccaaag caatcgtcca ctcttgatta
     3841 ttgcggatga tgtggatggc gaggctcttc caactcttgt tttgaacaag attcgtggaa
     3901 ccttcaacgt agtagcagtc aaggcacctg gttttggtga ccgtcgcaaa gctatgcttg
     3961 aagatatcgc catcttaaca ggcggaacag ttatcacaga agaccttggt cttgagttga
     4021 aagatgcgac aattgaagct cttggtcaag cagcgagagt gaccgtggac aaagatagca
     4081 cggttattgt agaaggtgca ggaaatcctg aagcgatttc tcaccgtgtt gcggttatca
     4141 agtctcaaat cgaaactaca acttctgaat ttgaccgtga aaaattgcaa gaacgcttgg
     4201 ccaaattgtc aggtggtgta gcggttatta aggtcggatc cgcaactgaa actgagttga
     4261 aagaaatgaa actccgcatt gaagatgccc tcaacgctac tcgtgcagct gttgaagaag
     4321 gtattgttgc aggtggtgga acagctcttg ccaatgtgat tccagctgtt gctaccttgg
     4381 aattgacagg agatgaagca acaggacgta atattgttct ccgtgctttg gaagaacccg
     4441 ttcgtcaaat tgctcacaat gcaggatttg aaggatctat cgttatcgat cgtttgaaaa
     4501 atgctgagct tggtatagga ttcaacgcag caactggcga gtgggttaac atgattgatc
     4561 aaggtatcat tgatccagtt aaagtgagtc gttcagccct acaaaatgca gcatctgtag
     4621 ccagcttgat tttgacaaca gaagcagtcg tagccaataa accagaacca gtagccccag
     4681 ctccagcaat ggatccaagt atgatgggcg ggatgatgta agctttctat agaaaacaac
     4741 ttataaaaaa cacaaaagga gggaatgact aacccttctt tttataggct ctttgtcaac
     4801 tgtagtgggt tgaaaaaaag ctaagcttga gaaaggacaa atttcgtcct ttcttttttg
     4861 atattcaggg cgataaaaat ccgttttttg aagttttcaa agttccgaaa accaaaggca
     4921 ttgcgcttga taagtttgat gagattattg gttgcttcca gtttggcatt agaatagtgt
     4981 agttgaaggg cgttgacaat cttctcttta tctttgagga aggttttaaa gatagtctga
     5041 aaaagaggat gaacctgctt tagattgtcc tcaatgaatc cgaaaaattt ctccggttcc
     5101 ttattctgaa agtgaaacag caagagttga tagagatg
//
LOCUS       DAVDZK010000076         5071 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVDZK010000076 DAVDZK010000000
VERSION     DAVDZK010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5071
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.077"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            85..374
                     /locus_tag="VUX16_002097"
                     /pseudo
     CDS             85..374
                     /locus_tag="VUX16_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            397..930
                     /locus_tag="VUX16_002098"
     CDS             397..930
                     /locus_tag="VUX16_002098"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET8124980.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPVLYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTELLPAL
                     KTPHVIVMGNTSFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            1270..1524
                     /locus_tag="VUX16_002099"
     CDS             1270..1524
                     /locus_tag="VUX16_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124981.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            1635..2144
                     /locus_tag="VUX16_002100"
     CDS             1635..2144
                     /locus_tag="VUX16_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124982.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKPQNWQN"
     gene            2132..2741
                     /locus_tag="VUX16_002101"
                     /pseudo
     CDS             2132..2741
                     /locus_tag="VUX16_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818859.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            2699..3262
                     /locus_tag="VUX16_002102"
     CDS             2699..3262
                     /locus_tag="VUX16_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET8124983.1"
                     /translation="MVPKTATSTETKIITRTIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVKSQEVTSDSSDKEITVRYDRL
                     STLEKPNPELPNQETPIPEPTPEPGTPKTETPVNPDPEVPTYETGKREELLNTGTEAN
                     ATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            3486..4355
                     /locus_tag="VUX16_002103"
     CDS             3486..4355
                     /locus_tag="VUX16_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET8124984.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQYMKQTAIQAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVVPIAA
                     AIAAVAVFKFLYL"
BASE COUNT         1745 a          889 c         1040 g         1397 t
ORIGIN      
        1 atttcagtaa aaaaaagtaa gtcttctaat aacaaaacat tgatatagtt gcttagtttt
       61 aaacaagcat attataataa agctatggca tatagtactg attttaaaca gcgagcatta
      121 gattacatca aagaggggca cagccatgtc gaggcagcca agttttttgg tgttggcgtc
      181 agaactctct tcacgtggga aaagaaagac gtaaacaagg acacatagag aggaaaaagc
      241 gagtcgtcaa aaaccgaaag attcctttag aggaattgaa agcctttgta gaggctcatc
      301 cagatgcttt tttacgggaa attgcggcac attttgattg tgctctgccc tccgtatggg
      361 cagctttaaa gtagattaag gtcactttaa aaaaagatga cgagctttaa ggaacaagag
      421 ccagagaaag tcgctgagtt tcttgatatt ttggataacc taaaagattt accagtccta
      481 tatattgatg aaacaggaat cgaccgctac ctctatcgtc cttatgcagg ggctcctaga
      541 ggggagaaag tctatgaaaa gattagcgga cgtcgttttg agcgaacttc aattgttgca
      601 ggacaagtag acggagagtt tatagctccc atgatttaca agaaaagcat gacaagcgat
      661 ttctttgtgg agtggttcaa aacagaactc ctgcctgctt tgaagacacc tcatgttatt
      721 gtcatgggca atactagttt tcatcccaag aacattttgg atgaactctg catccaagat
      781 aaacactttt tcttacctct accaccttat tcaccggatt tgaatcctat tgagcaagct
      841 tgggctatct tgaaaaagaa agtgacggat ttattaaggg aagttccaac tatttttgaa
      901 tgtttggaat gcttttttaa aactagatga ctataacggt tctaaaggaa cctatcgagt
      961 agtcattaaa actaaggata ctgctggtta agagaagacg gtatacgatc aaaccattca
     1021 ccgtgtagcc gaaatcgttc agaatgaaga cttgtataag gaaggtttga atgttgaact
     1081 tgcgcaccaa caaattaagg gattttttga agcagagttt aaaaatcgta ttaatggagt
     1141 tcttaatact aaaataaaaa atagtacatt aaatcgtgta aataaaaaaa ctatacacca
     1201 gagcaacaaa aactccatga tcaatttgaa gcagaagcaa cggaagatgc taaaaaacaa
     1261 ggcgatattg tgttgaatgt tgaccaggat ttcatgagca tatctaagtc taataaaagt
     1321 ggttcagact ggaagaaaac tttcacagtg aggacaacca ataggctagc aaatgacttg
     1381 aataatgtct tgaaacaggc tgataaagat actcctaata ccccaacttg gctaaactca
     1441 gctgcttcta aagctaaaga tgatgacaga gcatataaac tactgaagac tcttatacca
     1501 ggagaaaatt acctatcatg ttaaggataa tcagctagaa gtagaaacag ataaatacac
     1561 atatactgcc gctagaaatg gtagtaagga agttggtatt caagagtcag atatagcagc
     1621 aactctaagt gccgatgaat ataattctaa tcgccaaact tttgagagag aatacaaata
     1681 caaaagcaaa tgcccttaat aatggttggg ctagatctgg ttctgaagag ttcaaaaagt
     1741 tctcccactt tgtaggggta gacaaaggga ttgtgcgaac gaatgtactg actggtaaaa
     1801 aactatctga taagattagg aaagaagtgg gctctggaga tagcaaacta ggaaaaggcg
     1861 gctatttctc tactggggat gttctattag gaaaagatgt tgtttcttat accgtacaag
     1921 tattttcaga gaataatgaa agagtaggag taaacactca aagtcaccgt gttcagtata
     1981 atctcccaat tctagctgac ttttcagtca tccaagatac tgtggaacca tcacgaaccg
     2041 ttgttgaaaa aatcattcca aaactaaata ttcccgaaga agagaaaggg aaaataaccg
     2101 aagaaatcaa gaaaaagaaa aaacctcaga attggcagaa ctaatctcag aaaatgtgaa
     2161 agttcgctat gttgatgaac aagggcgttt gctatcattg aaaaatgata ctggaattgg
     2221 agaaaaagaa agtgacggaa cctacattac caataaaaaa acaactgatt ggtaccagct
     2281 ataatgtcac agataaaaaa ctcagtagca tgactactac tgacggaaaa tattatactt
     2341 ttaaagaagt agatacaaat tctgcaagtt taactgggaa tattgtaagc gaaggtagaa
     2401 cagtgacctt agtttataga gaaagcgaag cgccaaccac tgttacagta acagccaatt
     2461 actataaaga aggtagccaa gagaagttgg cagagtctgt tataaaagct gatttagcga
     2521 taggttctga gtataccaca gaatcaaaaa ctattgaagg gaaaacaaca actgaggata
     2581 aagaagaccg agttatcaca aggaaaacaa catacacctt ggtagcaact cctgcaaatg
     2641 cataccagaa gacggtgcaa cagttgacta ttactaccgt gagaatgttg aggaaacagt
     2701 ggttcccaaa acagcaacct ctactgagac gaagattata acgcgtacca ttcattacgt
     2761 tgataaagtt acgaaccaaa atgtaaaaga agatgttgtt caacctgtaa ccttaagccg
     2821 tacaaaaact gagaacaagg tcacaggagt tgtaacctac ggtgaatgga caacaggaaa
     2881 ctgggacgag gttgtatctg gtaagattga caagtacaaa gatccagata ttccaacagt
     2941 taaatcacaa gaagttacgt cagactctag tgataaagaa ataacggtaa ggtatgaccg
     3001 tttatcaaca ctagaaaaac caaacccaga actaccaaat caagagactc caataccaga
     3061 gccaactcca gaaccaggta ctccaaaaac tgaaactcca gtgaatccag acccagaagt
     3121 tccgacttat gagacaggta agagagagga attgctaaac acaggtacag aagctaatgc
     3181 taccttggct agtgctggta tcatgacctt gttagctggt ctaggattag gattcttcaa
     3241 gaaaaaagaa gatgaaaaat aatagatttt agaatctagg aacaaggaaa agctcacaga
     3301 tgtgggcttt tttcctggtt ttgagaacga ggtctttcgt gaagaataaa aacgcttata
     3361 aatctgttga actgggaaac tatgaatcct atttttttaa aaatatttcc agaaatcagt
     3421 tgctaaatag ggtaaaaatt gataaaatag ggaatatcta aaaaatttta aggagaatct
     3481 agcaaatgga tttcacatgg gcacttaagt atgccactga atttttggga actgccattt
     3541 tgatcattct tgggaatggt gcagttgcca acgttgaact taaaggtacg aaaggtcacc
     3601 aaagtggctg gatcgtcatc gctgttggtt atggtatggg ggttatgatc ccagccttga
     3661 tgtttggtaa cgtatctggg aaccacatca accctgcttt tactctaggg cttgcagtta
     3721 gcggtctttt cccttgggca caagtggtac cttacattat cgcgcaagtc ttgggggcta
     3781 tctttggtca agccttagtt gtggcaacat accgtccatt ctatttgaaa actgaaaacc
     3841 caaataacat cttgggaact ttctcaacta tttcaagtat tgaccatggt acaaaagaaa
     3901 gtcgctatgc agcaactgtc aatggtttga ttaatgagtt tgttggttca tttgttttgt
     3961 tctttgcagc tcttggtttg actaaaaact tctttggtgc tgaagtgctt caatacatga
     4021 aacaaacggc aatacaagca ggacaaacag ttgatttttc tgacttggct attaaagcac
     4081 aggtggctcc acacactgct tcaggacttt ctgtggctca cttggcactt ggattcctcg
     4141 ttatggcttt ggtaacatca cttggaggac ctacaggacc tgccttgaac ccagcccgtg
     4201 acttgggacc acgtctcctt catgctttcc ttccaaaatc agttcttggt gagcataaag
     4261 gcgattcaaa atggtggtat tcttgggtac cagtagtagt acctatcgca gcagcaattg
     4321 cggcagtagc tgtattcaaa ttcctttatc tctaagaaat agctccttta acatttgagt
     4381 gagcaccatc tataagtaag agaggatcag actggttctc tctttttgat tttttaggga
     4441 aatgaaagaa actctaaaca aactcctctc cagcagtggt attagaagtc tcagtgggct
     4501 attccagctt caatgggcta ctatagtggg ttgaagttgg aatagtcccc ccttctttct
     4561 caaacattgt gaggaattga tttaccttcc tcaacaaaat gttcagtttc tatttcattt
     4621 tgctataaaa taagcgatta ggggggctat tcttcgacct acattgactc tgctgagtcc
     4681 tatgattgtt atcgttttat ctgcaatttt atactcaatg aaaatcaaag ggcaaactaa
     4741 gaagctagcc gcaggttgtt caaaacacag ttttgaggtt gtatagtaga ttgaaactag
     4801 aataatacac atctacttct aaaacattgt tagaaatcga tttgactgtc ctgatcgatt
     4861 tgccctattc ttgtttcatt ttactatata aaccagagac tgtttacatt ttcagcaagt
     4921 gagtggatgg ataatgctga aaactccttg aaggataagt ctatttagta ctttctatta
     4981 attagttaaa tttttaccaa gaataattca caaaaacgtt gtaaaacact tgcaatttag
     5041 ctgaaatttg ataaaatagt aaggaaagtt a
//
LOCUS       DAVDZK010000077         4808 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVDZK010000077 DAVDZK010000000
VERSION     DAVDZK010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4808
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.078"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..1037
                     /locus_tag="VUX16_002104"
     CDS             <1..1037
                     /locus_tag="VUX16_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET8124985.1"
                     /translation="DRVSLEYGLPSRTILLNWLAQYRKNGYTIVEKTRGRVPESGECH
                     PKKVKRTPIEGGERRKTEIVQELMTEFSLALLLKVIKLARWTYYYHLKQLDKPDKDQE
                     LKAEIQSIFIEHKGNYTYRRVHLELRNRGYLVNHKRVQGLMKVLNLQAKMRQKRKYSS
                     HKGDVGKKAENLIQGQFEGSKTMEQCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAY
                     NLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRK
                     GNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLS
                     PVQYRTKSFG"
     gene            complement(1165..1368)
                     /locus_tag="VUX16_002105"
     CDS             complement(1165..1368)
                     /locus_tag="VUX16_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET8124986.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1361..2443)
                     /locus_tag="VUX16_002106"
     CDS             complement(1361..2443)
                     /locus_tag="VUX16_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET8124987.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVPADQEPILFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLNKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2569..3351)
                     /locus_tag="VUX16_002107"
     CDS             complement(2569..3351)
                     /locus_tag="VUX16_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET8124988.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVIVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3351..4694)
                     /locus_tag="VUX16_002108"
     CDS             complement(3351..4694)
                     /locus_tag="VUX16_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET8124989.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGVDSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
BASE COUNT         1445 a          950 c         1056 g         1357 t
ORIGIN      
        1 aagatagagt ttctcttgaa tacggtctcc caagtcgtac gatacttctt aactggctag
       61 cacaatacag gaaaaacggg tatactattg ttgagaaaac aagagggaga gtacctgaga
      121 gcggagaatg ccatcctaaa aaagttaaga gaactccgat tgaaggagga gaaagaagaa
      181 agacagaaat tgttcaagaa ttaatgactg aattttcgtt agctcttctt ctaaaagtca
      241 ttaaactagc tcgttggacc tactactatc acttgaaaca gctagacaaa ccagataagg
      301 accaagagct taaagctgaa attcaatcca tttttatcga acacaaggga aattatactt
      361 atcgccgggt tcatttagaa ctaagaaatc gtggttatct ggtaaatcat aaaagagttc
      421 aaggcttgat gaaagtactc aatttacaag ctaagatgcg acagaaacga aaatattctt
      481 ctcataaagg agacgttggt aagaaggcag agaatctcat tcaaggccaa tttgaaggct
      541 ctaaaacaat ggaacagtgc tacacagatg tgacagaatt tgccattcca gcaagtactc
      601 aaaagcttta cttatcacca gttttagatg gctttaatag cgaaattatc gcctataatc
      661 tttcaacttc acccaactta gaacaagtac aaacaatgtt ggaacaggca ttcacagaga
      721 agcactacga gaatacgatt ctccatagtg accaaggctg gcaataccaa cacgattctt
      781 atcatcggtt cctagagagt aagggaattc aagcatccat gtcacgcaag ggcaacagcc
      841 cagacaacgg catgatggaa tctttctttg gcattttgaa atcggagatg ttttatggtt
      901 atgagaagaa ctttagatct ttagaaaacc ttgaacaagc tattgtggac tacattgatt
      961 actacaacaa caaacgaatt aaggtaaaac taaaaggact tagtcctgtg cagtacagaa
     1021 ctaaatcctt cggataaatt aattgtctaa ctttttgggg ggcagttcat tctacaccca
     1081 ctattatgcg ttttattgtg ggaagatttt cctcattttc tagtgaaatt gaactttttc
     1141 taacatcttt tgatagatga cttcttaatc aattatcatt tccattgttg tttcttgggg
     1201 tttcatccct tgtctttgat aaaagcggag agcaccctcg ttatcattcc agacacttag
     1261 ggttagatta ttgcagccaa tttctttagc ataatagcag aaaaatgaca ataaaatagc
     1321 ccctagatat tttgaaagga aagcataggg gctatatagt ttaatcaaaa taaagcaaat
     1381 ctttgctggt gcttgtaaag aggtcgaagc catccttggt aacaacaccg cagtcttcaa
     1441 tacgaacacc gactttacca gggatataga tacctggttc aacagagaag cacatgcctt
     1501 cttcgatgac catgtcgttt ccttccatga tagatgggaa ttcatggaca tccataccga
     1561 taccatgccc gagacggtgg ttgaagtact caccataacc agctttttcg atgacctcac
     1621 gggcagcgcg gtccacttca tgagcagtca cacctggctt gataaagtca agagcagctt
     1681 gttgggcttc aagagtcaag ttgtaaatat ctttcttgaa ttggtctggt ttgccgacag
     1741 cgactgtacg agtcatatct gacgcatagc cattgaccag aacacccagg tcaaagagga
     1801 gaagagcatc attttcaacc ttattagctg ctggaatgcc gtgtggattc gcagcattat
     1861 caccagtcaa gaccatggta tcaaagctca tttcataacc ttcacgtttc atggcaaagt
     1921 cgatttgtgc gatgatatct gtctcagtct tattaagaga aatattgtca aaaccaacat
     1981 gaacagcctt gtcagcataa agacctgcaa ccatcatttt ttgcacttca tcagctgatt
     2041 tgatgaggcg catgcgttgg atacgaggag tgaggttgtc aaactcagca gtctcaaaaa
     2101 ctgttttcaa accatggtat ttggtcaaga tgagattgtc aaactcaaca gcgacacgtt
     2161 tgaagtcaag ttgtggaaga gcatgtttga ttttttgcca tggattttca gaatcgacat
     2221 agcccactac tgggaaggaa acggtgctac ttgcacgttc tacttcaaga gctgggacaa
     2281 agaggatagg ttcctgatcc gctgggacaa agaggaacat ttggcgttca tggggatcac
     2341 tgtaaaaacc agtgaggtaa ttgattgtga cggggtcaga tacgacagcg acgtctagtt
     2401 tttctgattc aagatatgtt aggatttgtt gtaatttaga catatgctac cttctttcta
     2461 cccctctatt ttggcaaaaa atgagagaaa atgcaaggga gaagggtaaa agaaaagaca
     2521 aaaaactccg acaagataac ggagttcttt gatatcattt tcctttgttt aagaaaagtc
     2581 agccttgctt ttgacgtcac tgtactcttc agcgatttct tggctgagaa tatcctcata
     2641 ggcagggagt tggatgtcct gaccatattt cttcttgagg gcagtagtaa ctaggcgata
     2701 agccagattg gcattacgag agaggatagg cccgtggaag taggaaccaa agacattctt
     2761 ataatgaacc ccttcaccga ccttttcttc gttgtttcca tttccataga caacctgtcc
     2821 cagcggtttt tggtcatcag agaggaaggt acgaccttgg tgattttcaa atccatagta
     2881 ggtttcatcg aaatcttcat tgtgaatctt gatgtcaccg ataaaacggt tattggtctg
     2941 gttgagcgtg tagtgtccca tgacccctag cccttcgata cgttttcctg aagcttcaac
     3001 ataatattga cccaatagtt ggaaaccacc gcagatagcc agaactacac cgtcgttttg
     3061 gatgtagttg tcaatgctct cttttttagc aggtaggtcg tctgcaatga tactttgttc
     3121 aaagtcttga ccaccaccga aaaaggcgat gtcgtagtga ttttcatcaa agtcatcatg
     3181 gagagaaacg atgtcaacga tcacatgggc tcccagtttt tcagccacat acttgagcat
     3241 gaggatgttt ccattgtccc cgtaggtatt catgagattt ccgtagaggt gggcaatgtt
     3301 gagctgatag gggtaattgc catcttttga ggaaagtgaa gtataaacca ttagttcatc
     3361 tcctttctaa caatctgacg actagccagc agttcacgaa attccagcat ggcagtataa
     3421 gttgccagaa tataggcatg cttgcagtct tgattctcaa tggtcttgag aacttgctcc
     3481 agattactcg tttcagtgat tttctcagct ggatagccag tcactcggag gcgacgagcg
     3541 atttcagaat gacgaacacc gccagcgttg atttcaggaa tgtccatgtc agtgatttgt
     3601 tcaaagtctg catcccagat ccagctagtg tcaattccat ctgcatagtt ggcattaagg
     3661 aggacagata ggctaaatgg ataaggtgct agtttgatca tttcgatagc ttgggttgca
     3721 ccgactggat ttttaatcaa gacaagggta cattccttgt caccgatatg aaaggtttct
     3781 tggcgtccaa agacagcacg gctcttgtca aatccctgtt tgatgagttg cgaatcgaca
     3841 cctaggaaac gggcgatggc cacagcagct agggcgttat agatattata gagcccgccg
     3901 atttggatac cgtattcttg gccgtctatg acaaagcgag agcgattgtt ggtcaactca
     3961 accagttttg tcaaacgata gtcgagatca ggacgtttac atccacaacc ttcacagata
     4021 taggcaccca agtttgcata ggtattatgc tcatatttga ggatgccttg gcagtcagga
     4081 cagagaatcc cttcggtatt gtagtgagcc agttgggctg gtcctttttc caagtcaaaa
     4141 ccaaaatact ctatagggtt tggaatagtt ggcttgtaga aaagtggact gtctccgtta
     4201 aggagaacag tagcagttgg aactttccga atggcatcca atatcatgtt ataggtagta
     4261 tagatttcac cgaaacggtc catctggtca cggaagatat tagtaatgac aaaaagacta
     4321 ggctggatat agtcacagat acgagataga ctggcttcgt cgatttctag gacggcaata
     4381 tttttcccag ttttagaaga tttggctgtt aagaaggttg tcgcaattcc tgtaatcatg
     4441 ttggcaccgc ttgggttggt cagaacttga ccataaactt cttttaaaat accgacagtg
     4501 agggcagttg tcagggtttt tccatttgtt ccagtgacaa cgacaatctc gtagttctta
     4561 gctaggcttt gtaaaatatc tttatcaaat tgaagggcga ctttccctgg gagcgtactt
     4621 ccacgtccaa gacggcttaa aacgaagtgg gaagaacgcc cagcaagaag gcccaaagta
     4681 gtttttaagt tcatgtttct attatatcac aaaagaggga aaagacagat ttggtgtttc
     4741 gtagaagtaa aaacagccca aagagggctg tcagttaaga tgagatttca acttaaatcg
     4801 caaacaag
//
LOCUS       DAVDZK010000078         4437 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVDZK010000078 DAVDZK010000000
VERSION     DAVDZK010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4437
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.079"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(1..1353)
                     /gene="rlmD"
                     /locus_tag="VUX16_002109"
                     /pseudo
     CDS             complement(1..1353)
                     /gene="rlmD"
                     /locus_tag="VUX16_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050284.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
     gene            1410..2186
                     /locus_tag="VUX16_002110"
     CDS             1410..2186
                     /locus_tag="VUX16_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HET8124990.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQEAKIASWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2196..2972
                     /gene="recX"
                     /locus_tag="VUX16_002111"
     CDS             2196..2972
                     /gene="recX"
                     /locus_tag="VUX16_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET8124991.1"
                     /translation="MKITKLEKKKRLYLMELDEQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTHKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVNQETIQELILKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            3061..3594
                     /locus_tag="VUX16_002112"
     CDS             3061..3594
                     /locus_tag="VUX16_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET8124992.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(3952..4194)
                     /locus_tag="VUX16_002113"
                     /pseudo
     CDS             complement(3952..4194)
                     /locus_tag="VUX16_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
BASE COUNT         1472 a          800 c          744 g         1421 t
ORIGIN      
        1 aaactttttt tattaatttt acaacagctt cagttcgagc tgtatgtggg aacatatcga
       61 ccgactggat ataatgaaga tcatagactt ctactaagcg taccaaatca cgagccaagg
      121 tcgaaacatt acaagaaata taaaccattt tttctggtac ataagtaaga atagtatcta
      181 ataacttatc atccagacct gtacgtggtg ggtcaacaat caaagcatct gctcggtagc
      241 cttccttgta ccaacgagga ataatctctt ctgccgttcc agcttcataa tgagtattgt
      301 caaatcccat tcttttagca tttcgcttgg catcttcaat agcttctgga ataatatcca
      361 tacctctgag tgtttttact ttctttgcaa aggcaaatcc aatcgttcca actccacaat
      421 aagcgtcaat caaatggtct tctttatcaa catccagcgc ttttactgct tcgctataga
      481 ggacttctgt ttgctcagga tttagttgat aaaaagctcg aggggatagt gaaaattcat
      541 aattgagtac accttcttga atactctctt gcccccagat aatctctgtc ttttcaccat
      601 atatctcact ggttttagct gtatttgtat taacagctac tgtcacaact tctggaaaat
      661 ctttaaccaa ctcttttacc agttgggtta aattaagctg gcggtttgta acaataataa
      721 tctgaacctg tccggtcttt ctcgcgcgtc ggaccataat agtacggaca cctagaactt
      781 ttctctcatc cgtgattgga atctggtgat aagtaagtaa ttctgctaag cgattagcaa
      841 tcacttgggt ttccttatct tgtaccaggc agtctttcaa ctctactaaa tagtgagagt
      901 tttgtgcata taagcccgcc ttgacctgat ttttaaattt tcgagtctga aattgtaact
      961 tagctctgta atattttggt tcctgcattc caatagttgg acgaatttca taattttcat
     1021 atcctgcagg agcaaatttt ttcagcgctt gatgaagtaa gtccgtcttg aactccagct
     1081 gcttatcata atgcaggtgc atgatttggc agcctccgca ttcattataa atagtacaag
     1141 atggcacaat tcgaaattta gacttcttgt tgaccttcag taattttgct tcaacaaagt
     1201 tgcgtctaat agaagtaatc tgacaataga tatcttcgcc tttgagagct ccaggtacaa
     1261 agactaatgt ttttggtaaa agccgattcc ctcaccatta attcccatgc gtttgatttt
     1321 taatggtatt ttttgtttca ctttcagatt catatgtcta ttataccatg gagtttctaa
     1381 gatatttaag aatatgttac aataaaagca tgaattcaaa aacacctcgc tttagtatac
     1441 tagatttccc tgaacaatta cgaagctata tcaagggagc taatctctct gatagttctt
     1501 ctcattcaag tgcaactgtc ctatatatag attcaggtta ctatttaaaa atagatcaaa
     1561 aaggcagatt agctcaagaa gctaagattg caagttggtt cgaaactgaa ggattgggaa
     1621 ctccagtgat tacctattta tcagcaaata aggacttcct tctgactaaa gaagccattg
     1681 gcagcaacgc tctcgctttt ttaaatcaac ccgaaagact ctgtcaaacc ctggctcaag
     1741 cattaaacaa acttcacagt cttaaaccac aatcttttcc gtcggaaaat catctgaagc
     1801 gttataaaga aaaagcctta aaaaactatc agaaggggac tttttataac aagactcttc
     1861 tgcctcaatt tcacattcac agtcgtgaag aagcttacca actgatacaa gagaaaggtt
     1921 acattctcaa agctgatgct tttattcatg gagatgcctg cctgccaaat ttcatcttga
     1981 aggatgcctc tcatttttct tgctttattg acttgggatt ggctggtttt agtgaccgac
     2041 atatcgacct cttttgggca atttggtccc ttcattacaa cctacaagat gctacgtatg
     2101 ctgaattatt tctcgactat tacggtagag aatatgtaaa tatggataaa ctacgacttg
     2161 ttgcagcttt cgaagcattt agatgaaagg aaattatgaa aatcacaaaa cttgaaaaga
     2221 aaaaacgtct ctacttgatg gaactagatg aacagcaaac ctcttatatc acggaagata
     2281 ccattgtccg ttttatgctg tctcgagata aggtcattag taaagaggaa ctgaccgaga
     2341 ttcaggattt tgcccagttt tcttatggta agaatctcgc tctctaccac ttatccttta
     2401 aagcacgcac tgaaaaagaa gtcagagaat atctgaaaaa atacgatatt gataaaaaca
     2461 tcgtttctca agttattgct aatcttaaag aagataagtg gattaatgat ggtcagtacg
     2521 cttatgctat catcaatacc aatcaacttt caggagacaa gggtccttat gtgctgactc
     2581 ataaactagc tcaaaaaggg atttcaaaat ctactataga agagaacttg aaagaatttg
     2641 atttttctga agttgctcaa cgtgtagcta ataaactatt gaaaaaatat gagggaaaac
     2701 ttccatctcg tgccctgcaa gataagatta tccagaactt gactaacaag ggcttctctt
     2761 attctgatgc taaaattgcc tttgacgact tagatagcca agttaaccaa gaaacgattc
     2821 aagaactcat cttaaaggaa cttgataaac aatatagtaa gtatgctcga aagtatgaag
     2881 gatacgaact gaagcagcgt ttaactcaag ttttagcacg aaagggctac gatttttcgg
     2941 atatagcaag cgctcttaga gaatatcttt aatatttcca agtgaaattc acagatttta
     3001 ggtaatttta tggtacaata gtaaatgata aacttataaa ttgtagaaag ttggttagtt
     3061 atgaagcttc caaaagaagg cgactttatt acaattcaaa gttataagca tgatgggagt
     3121 cttcaccgaa cttggcggga caccatggta ctaaaaacaa cagaaaacgc cattatcggt
     3181 gtcaacgatc atacacttgt taccgaaagt gatggtcgtc gttgggtcac tcgagaaccg
     3241 gctattgttt actttcacaa gaaatattgg tttaatatca ttgccatgat tcgtgataat
     3301 ggaacttctt actattgcaa tatggctagc ccctactatc tggatgaaga agcactgaag
     3361 tatattgatt acgatttgga tgttaaaatt tttacagatg gagaaaaacg tctcttggac
     3421 gttgaagagt acgagcgtca caaacgcaaa atgaattatt ctgatgactt ggactatatt
     3481 ttaaaagaac atgtcaaaat tcttgttgat tggattaaca atggacgtgg tcctttctca
     3541 gaagcctatg taaacatttg gtacaagcgc tatgtagaac taaagaatcg gtaaagttgt
     3601 caaaggtcag gaacaaaatc ctgaccttgt ttttttggta gtataaaata aattgtgtaa
     3661 acacaaaaag gaataaatcc attatagcag agttacaaca cattactaga aagagattta
     3721 tgcagaattc gtaaaatata taaaacaaat agatatactg ttatttttta atgtctttat
     3781 tccttgtaag tttacaacaa acttatatcg tttaatacaa aaaatacgaa aatgattagt
     3841 ataaaaaata caggtcaact tcgtatcaaa aacatttttt tgtatttcca catagcatca
     3901 atcatttagt acagtatttt aaaaacaata tctcaacaga gaaaatgcta tttaatctat
     3961 cagctcattt aatcgttttt gaaaatataa agcaatactt ttagattcaa taaactcaaa
     4021 atattttatg acattgtcca tttgtttaat tccagattct ttagattctg tcaggtatat
     4081 tttatatcct tctacaaatt tgaatgtaga tttttcaaaa acttttgtgt catcctttaa
     4141 taattttttt aatttcattt caaagtagtc tgcatatatt agatgtgaat tttcggctct
     4201 ataatatttg tagtgggtaa atcccttata gatattatgg agcctatttt gttgtagaaa
     4261 aaaagtccca tatgacctat aatgaaaagc gacaaaacaa ctcattaaaa aaaatcatat
     4321 ggaacaatta cattttatca caaaattact agacattaaa gaccctaata tccagatttt
     4381 agacatcatc aataaggata cacacaagga aatcatcgcc aaactggact atgaagc
//
LOCUS       DAVDZK010000079         4269 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVDZK010000079 DAVDZK010000000
VERSION     DAVDZK010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4269
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.080"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..548
                     /locus_tag="VUX16_002114"
     CDS             <1..548
                     /locus_tag="VUX16_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET8124993.1"
                     /translation="VKDGIIDGDRGKNYPKSDELFSEEYCLFLNTKNVTKNGFSFDTK
                     QFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRINSGMLILRPKTP
                     NLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQNEFADFVTLVDK
                     SQFACEIAIKVWRNSLKFSII"
     gene            578..3928
                     /locus_tag="VUX16_002115"
                     /pseudo
     CDS             578..3928
                     /locus_tag="VUX16_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         1401 a          681 c          868 g         1319 t
ORIGIN      
        1 ctgtcaaaga tgggattata gatggtgata ggggcaaaaa ttatcctaaa tcagatgagt
       61 tgtttagtga ggagtactgt ttatttttaa atacaaagaa tgttactaaa aacggatttt
      121 cattcgatac aaagcaattt atcactaaaa caaaggataa attacttcga aaaggcaaac
      181 ttgagcgtta tgatatagtc ttgacaacaa gaggtactgt tggaaatgta gcgtactacg
      241 atgaattaat aaaatataaa catttacgta taaattcagg tatgctaata ttacgtccca
      301 agacaccaaa tctaaatcag aaatttatta tccatgtttt aaggaataat aattatagtc
      361 gagtgatatc aggaagtgct cagcctcagt taccaattac aaaattaaaa aaaatacttc
      421 tccccctccc cccactagcc ctccaaaatg agttcgcaga ctttgtaacc ctggtcgaca
      481 aatcacaatt tgcttgtgag atagctataa aagtgtggag aaatagcttg aaatttagta
      541 taatatagct aaactatttg tttaaagtga gaaaaaaatg ggaaatttta gctttctttt
      601 aaaaaatgac gaatatgaat ctttttcaaa accttgcatt gaagctgaaa atatgattgc
      661 tacatcaact gtggctactg cctttatggc gcgtcgtgct ttggagcagg ctgtccattg
      721 gatatatagt cacgattcat atttagaagc tccctatcgt gctactctat cttctttagt
      781 atgggatgat gattttaggg atatcgtaga ttctgaactc cacaagcaga tagttctgtt
      841 gattcggtgg ggaaaccatg ctgctcatgg tggtgaaatt aaggaacgag aagcgatttt
      901 agctttacat catttgtatc agtttgttaa ttttatcgat tattgttaca gcaatgaatt
      961 tgtggagcgt tattttaatg agaagtgctt accactttca gcaaacatca aataccgaga
     1021 aactccacaa tctatgataa agttacaaga cagtttacca gaactgcctg attttcatga
     1081 acagatggct gctcagtccg tagaagttca agagacttat actgaaaaac gtgagactgc
     1141 agcgcaacgg caagatgtgc ctttccatat tgaacaatta tctgaggcag agacaagaaa
     1201 gctctttatt gatatcgatc tccgtttagc aagatggata tttgaagaaa actgtcgtgt
     1261 tgagatagcc gttgatggtc tcaagcacgg ttcaggaatt ggttactgtg actatgtact
     1321 ttatggtaaa aatgggaaaa ttttagcgat tgtagaggct aaaaaagcct ctgtcaatcc
     1381 agaagtaggg gaagtacagg tcaaagaata tgctgaagct cttgagaaac atatcggcta
     1441 tcagccaatt tgctttatta caaatgggtt gaagcactat atacttgatg gtccgaaccg
     1501 acgccagatt gcaggctttt actctcaaga agaattgcaa ttagtgatgg atagacgtca
     1561 tcttcaaaaa ccacttgagg atatttctag taaaattaga gacgatattt ccgggcgtta
     1621 ctaccaaaaa catgcgattg caagcgtttg agaagctttc tctgatcatc gtagacaggc
     1681 acttttggtt atggcaactg gggctgggaa aactcgtaca gcagtttctc tagttgatat
     1741 cttatcacgt cataactggg taaaaaacgt tctcttctta gccgatagaa cttccttggt
     1801 taagcaagta tatgattcgt ttagaaaatt actcccagat ctttccgttt gtaacttctt
     1861 agaagataaa gaaggagctc aatcaagtcg catggtcttt tcaacttatc cgaccatgat
     1921 tggagcgatt agtggtcaag aagaagtaaa tcaacgccct ttcactgttg ggcattttga
     1981 ccttatcata attgacgaat ctcaccgttc tatttatcag aaatacaagt ccatttttga
     2041 ttattttgat gcaagaattg taggcttaac agctactccg cgtcaagatt tagataaaaa
     2101 cacctatgga ttctttaatt tggagaatgg ggttccaaca tatgcatatg atttggaaga
     2161 ggctgttaaa gacggatatt tagtagccta tcattctatc gaaaccaaac tgaaactacc
     2221 tacggatggt ctacattatg atgatttgtc cgaagaagaa aaggaacatt ttgatagcaa
     2281 atttgaagac gatatctgtg aaaaagatat tgatgggagt gtatttaatt cctttatttt
     2341 caataaaagt acagtagaaa ttgttttaaa tgaactcatg acaagaggaa ttcagacagc
     2401 ctcgggtgat gaaattggta aaactattat ttttgctaaa aatcatgatc atgcggaata
     2461 tatcagaggt atttttaaca accgctatcc tgaaaaaggg agcgactatg ctcaggtgat
     2521 tgattatagt attaagcatt atcagacctt gattgatgat tttaaaatta aggagaagta
     2581 tcctcaaatt gcgatttctg tcgatatgtt agatacaggt attgatgtac cagaggttgt
     2641 taatttagtc ttcttcaaga aagtacgctc taaaactaag ttttggcaga tgattggtcg
     2701 aggaacccgt ctatgtaaag atttatttgg acctgagcag gataaggaaa acttcttggt
     2761 atttgattat ggggacaatt ttgattattt tcgtgcagat ccaagagatg gagagggtcg
     2821 tcacattgtt tcgctgactc agcgtttatt taatatcaaa gtggacttga ttcgagaact
     2881 tcagggactc caataccaag aagatcagtt tgcgagagca taccgtcagc agcttgtctc
     2941 ggaacttcaa ggtcgtatag agagcttaaa tgagttggac ttcagggttc gtatggtttt
     3001 agatacagtt tatagctata ggaaattgga aagttggcag aatctaactg ctgttacaag
     3061 tgaaaccatt caaaaaaatc tctctccgct tttatttgat gaagataaag aagatgagat
     3121 ggccaggaga tttgatttgt ggttgcttca tattcagttg gggcaactga cagctaaatc
     3181 ttccactgtt catatttccc aagtgatgaa gacggctaga gctctttctg ctattggcaa
     3241 tatcccgcag gtttttgagc aggctgaaat tatcaggaaa gtacaggagc ctgaattttg
     3301 gaaagaagtt aacttgtctg atttggaaaa aattcgtctt gctattcgag atttattaca
     3361 gtttttggat aaaacagacc gtaaacccta ctatgttaac tttgaagatc gtatactctc
     3421 cactgttcac gagaccacag catttttgca ggtcaacgat cttcggtctt acaatgaaaa
     3481 agttgagcat tatttgaaaa ctcatctgga tgaggagtcc atttctaagc tataccataa
     3541 taaaaagttg acatctgatg atatgcttgc acttgaaaaa ttgctttggg aaaaattagg
     3601 tagtaaagca gactaccaaa gtcattatga aaataaggca attccgagat tggttcgtga
     3661 gattattggc ttagatagag agtctgccaa tcgtattttt tctaaatttt tgtcggatga
     3721 gaatcttaat gccaggcaga tttcatttgt aaaattgatt gtagactaca ttgtagaaaa
     3781 tggtttttta gagacgaaag tgttaacgca agagccgttt aaatcttatg gttctgttca
     3841 actactcttc caacaccaac taccagtact tcgtaatatt gttcaaatca ttgagctcat
     3901 caataatcga gctggagaag cggcttaaat tctaaagtga ttgccatgct gagactcatt
     3961 taaaattaaa aagagtagaa atttatgcta tatatgagaa gttttattag gaagaatgtc
     4021 atcgttttcc tagaatacag tatcagttgt taagtggttg ataaatttca aagtagatac
     4081 ttgtaccacg atgtttgttg atcgagttat taacaaaaga gctactttga ttttaaagaa
     4141 atagaaaaca aaaagccgag caagaattca attgcaggag aaaatgaaat aatactcaat
     4201 gaaaatcaaa gagcaaacta ggaaactagc tgcaagctgc tcaaaacact gttttgaggt
     4261 tgtagataa
//
LOCUS       DAVDZK010000080         3935 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVDZK010000080 DAVDZK010000000
VERSION     DAVDZK010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3935
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.081"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            767..1138
                     /locus_tag="VUX16_002116"
     CDS             767..1138
                     /locus_tag="VUX16_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HET8124994.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            1146..1358
                     /locus_tag="VUX16_002117"
     CDS             1146..1358
                     /locus_tag="VUX16_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124995.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            2240..3298
                     /locus_tag="VUX16_002118"
     CDS             2240..3298
                     /locus_tag="VUX16_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124996.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIIKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
BASE COUNT         1311 a          468 c          740 g         1416 t
ORIGIN      
        1 gcgttgcaag attttctcgg attattgaca aataaacgga cattctgata gacgattgcc
       61 ctagcggctt agtgtaaact ttacaaattt ggcttgtaat ttttttataa aattcacttt
      121 agttacttga cagttattat attttcgctc ataatataga taaaaggatg ggataggagt
      181 ttaaaaattt gaaagcgcta tccataatcg taacgcataa ttttctcctt ttcgtgaaaa
      241 aagttaacgt aattttgaaa tgagcttaat aagaggtact atgtaggtag aaaataaaga
      301 taggagaaaa agtatgaata aaaaaatatt ttgtattcta gtatgtatta tatcattgat
      361 tagtctagct ataatctttc catggggctg gtcgatataa tgtaagggag cttgagttgt
      421 tagtagagga taaaatgtta agagtaatag tagttattca atctttagta ataatactgc
      481 ttgctgttgc tttattatta tctcggaaaa actttgattc gttaaatgtt gttcttataa
      541 tgatgatcgt atcacaattg ttgttattag tatatttgat aaaatcaggg aatcagtgat
      601 tagctgttat ttgaattaag taaactgtta agcttcaagc agtaactggt tttaaatatt
      661 taaaataaga taaaggaagg aagtctaatt taggtaacta aacaaagcct gcgatcactt
      721 gttaggaaac catcctaagc atgcttaata aaaaaggaga aaataaatgg aacttgtatt
      781 accaaataat tatgttgtga ttgatgaaga agagatgatg taccttgatg ggggggctat
      841 atatataccc aggtgggcaa ttacaggagc cattactggt gcagcatatg cagcattagc
      901 agcagcagga ggtggaggcc ttcaactagt tcttgcatct tatggattac gctccgcact
      961 ggtagctggg attgttaaag gtttaggagt attaggaatt catattggaa atgcttttgc
     1021 aaatactgtt attagaagta ttgcatctgc tggaattggt gctggagctg attggatttt
     1081 taccaatatt attgatggct gggatgggcg acgtgataat caattgagaa taggataata
     1141 atcttatgtt gattgtttta atttcagtta ttgttgcatt cctgtatcat aaaattacag
     1201 agtatgtcaa caacaggaaa attgatattg ttatttttct atcattgctg atttctcatt
     1261 ttatttggaa ttactatttt ttaccaattg aaatattgat agcaatcagt ggagcaaatt
     1321 tattattaag ttttttaaaa aaattacaga ttaaataata ttattccata tgacatatca
     1381 actaggtcat tagattttat tgaagatata aattaaaaac gaggttggga aaaaactcaa
     1441 tttgaaagtg agattgagta aatctttcta tctatataac gtatatcatc aatatttttg
     1501 aacacctgat aatatgcact tttcttattt taaagatttt ttgcctttct tcatttcttg
     1561 aatgaatcgg agagatgact ttatttaggt gtttgacatt actatagata ggatttagca
     1621 gtactaatat gaactcatat tataggtgca gacttaaatt ttggaagcaa gctaaaggat
     1681 atcttatcta ggtaactaag tgctataaca agatatattg gtggagttag tatggcaact
     1741 attactaatg ctcttaatat tgcggctact gttgctgaag tcttctcatt aggaggagcc
     1801 attgcatatg gtttagatat cgtagacggt aaatttgatg ggtatttatg ggcgtaaaat
     1861 tatagctatg aaacattttt ttgcaggaat tggtgaaatt cattttttgt tatttttatt
     1921 atatctaagc atgtctgcta gtccaattat tggactagtg attggatata ctaaaataaa
     1981 tctaataaat tctattatta tagctcttgg tatgatattg gtattaattt tggtattatc
     2041 aagagtgtat agaaaatatt tttatagaga cgatgatgac taaagttttt atcaataatt
     2101 tgggctcctt gtcaactgta gtgggttgaa gaaaagctaa cgtctgggga aggggttaaa
     2161 gctttgcttt atcaaatatt gacttacaga gttgctctat tgtattgatg tattcttagt
     2221 aaataatatg gtgttttgaa tgaaagatga tcagaaatat ttattagcgg gactttattc
     2281 gcttctagtt gcaatatttt attttccatt gattgagtcc aaggggattt ttgtaagtat
     2341 attgatggcg gttttacttt tatatttaat atacttcatt gcaacagtca ttcatattgt
     2401 gataattaag tttataataa aaaaatcttt taagtatttg gttctatatc catttactta
     2461 tgatgggagc tggagatttc aacctataaa cttactctac tttccagaaa tggtgagaga
     2521 tgtcattccg attaatttag ttcaagaata ttgccaagga caaccttacg gactgttaaa
     2581 aaagatgctg aaaagaattc gattgtcacg agagatatct ttactcctgg ctaccattat
     2641 cgtctatttt tttacgcata gaattctacc tctttcagta tttacgttca tattttctta
     2701 catattgcta tttgcacaat cttatttggg tggtaatacc gcttggattg gaaatagaag
     2761 attaataata gatgatgaat ttgaaaaaat cttgctttca aaaagttata taaaagaaat
     2821 atcatctgca cgatactcag aatacttgac atgtgaatac aaaaacctta caccaatcat
     2881 attgttagct atttttgaaa atttgcttga ctcctacttg cttcagaatc agagtgaggt
     2941 tgacttagat attttttata aagttttacc tttgctttat aaagaaaaat atactatggg
     3001 attcaattac tttgtaagtt taaattattt actatataag gttggatttt tgggaatcat
     3061 ttacgataat gaagcattaa gagatttgtc aaaacaatat ttaaacaaaa atatttcgga
     3121 attacaagat ggttctttcg agggcggtat acaagatgct gttgcttcta aacaaatagt
     3181 agttataaat gaatttatag cttgtttaaa ttccagatgc gtgccatccc aatatgatag
     3241 atttttttat aaagatagac cttatatttt ttccagaaag agtcctatta aggggtgaaa
     3301 atttgttaca tttggattaa caagtgtcct agggattaga aataactcta gtatagctag
     3361 atatttttga gtaactagaa atatcattag gctacccata tgattgccag aaaagatggc
     3421 tgatggatct tatttatact gttgcagtag gcgttgtcta ggataaataa gctatcttga
     3481 tgggggagat tggaataatt ttagtagaaa cattaaagga ttatggacaa gtagcgcagg
     3541 attaggtgat gcaatgtgca aggatatctt tatatgagtt tatcggtgat attttctatt
     3601 ctaaaataac aagttgttgc atcgtagcta aggatttatc taaaaatact atgaaattgg
     3661 acgtcatatt ttttgaggat agaaataaaa gatccgcagt tttaggttta cgaagagaca
     3721 aaagcggagt atttaaacca gttactctac attttacaag cgctaagaaa tatgctaaag
     3781 ttcgtaaaac agatgtgaaa gaaatgaaat ggctataaag attgtccgca gacttgagct
     3841 tgcgtttttt gttgtttaac gaaattaaaa aacaagctct ctcaatcgga aatgttttta
     3901 taggaatgaa ggaagatgat actatgttta aaaag
//
LOCUS       DAVDZK010000081         3562 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVDZK010000081 DAVDZK010000000
VERSION     DAVDZK010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3562
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.082"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..>3562
                     /locus_tag="VUX16_002119"
     CDS             <1..>3562
                     /locus_tag="VUX16_002119"
                     /inference="COORDINATES: protein motif:HMM:NF020018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124997.1"
                     /translation="PIIRSNSDTLLSTAVEDAVTVTNKENVEKQGNLPTGIGKHTINA
                     KVTYKDQSEEMVEIPYTIKPDAPSISTSIGTAGKNSVTVNNVTPGTTVVVYDMTNPNN
                     PIELGRKDVSGATADAAQNGVTVSTNATLRKDTPIAAEVIYKPTVAAERISSDKSSSL
                     VVKEGLAVNSIHAVKGENYTGDLASRIHYNDGQDTGLPAGSTVEWKNNQAPDYNNVGT
                     SRYTLVVNVPNQGTTEIEVPVHVYPTASLKKASYTNKQGTLSNGTDASKYVQFEGSAD
                     TPNNVTVRWKDGVPDVSTVSADRKAKIEVVYPGNASATDTVVKELEVSLPTYHSTAKS
                     TEYTRTIGEAYASTDASDYVETTPNTPRGTEYAWKTDETGNQAYGSSTWGGANGDWLG
                     KKTNKVKVYYPNADGGNEKSEVLAEETEEITFITKPAKPSITSDLTWASGTRTTVEVG
                     NVTSGTRVVLYDEQGNELGHTDVAKGANYATPTTASITPTKALPTGKVYVKTIYMPDT
                     ADQRVESEKSDEATAKTNTLTAKGIIQTLAGPGNIGGVGTLDAATLGKLLRQENGGTD
                     FTGATAEWKDKTNLEKGNGGSRVEHLLVQLKGHSEKQDVAITVTSLTPPSAKAVLKSK
                     GADLTNDNLADYVTAEGQGTLSWEGNPAKVEVGQALPRIKVTYPTTGVAITDITDQYV
                     DAKVYSLEANSNAKTRVTVGDAFDPSAGDYVQTVANTADLPRTGVSHAWKDGNKPTSA
                     TVGKATYTVVTSFGNDADVPAELRGQDVETQVEVTVLSTKPSKPEASQNRTDLSITVV
                     VGKDDATKAEITFKDELDQEHTVSFTKGANGQWDKDDANSQPTVQIINNADGTATVHM
                     TGGTAKAGSTVVTKQQKADSDFSDISELVVKEHLKGATVTTKDDGSVEVVVPKEADTA
                     TVSYVPEGQTQAKTVTITKGQDGNWTGPADSDLVIKKDDATGRVTVTVPADKVADGST
                     VTGRVDSATGLSPEVEVKGKAPQPSEFSHHVRDNGDEVITLPQNADSVTLNYPVSDAN
                     VKTVTISKGQDGTWTAPADSDLVVKKDDATGSVTVTVPADKISGNRTITASAKAGSGD
                     GESKERTFTTTVVERQAPTVSEVTVAANGTLSAEQINAAVTAPKKVSAVAAEALKQVA
                     AGSNTEIPVTVTYADGSTETVQLAVYSKQVTPSTVGFQQK"
BASE COUNT         1250 a          755 c          864 g          693 t
ORIGIN      
        1 cgccaatcat tcgctcaaac agcgacacgc ttctctcaac agcagtagaa gatgcagtaa
       61 ctgtaaccaa taaagagaat gttgaaaaac aaggaaacct tccaaccgga attggaaaac
      121 ataccatcaa tgccaaggtt acttacaaag accaaagcga agaaatggta gagattccat
      181 atactatcaa accagatgcg ccaagcatta gcacaagtat cggtacagcg ggcaaaaata
      241 gtgtgacggt taataatgtg actccaggca cgacagtagt agtgtatgac atgacaaacc
      301 caaacaaccc gattgaattg ggacgcaagg atgtgtcagg tgctacagca gatgcagcgc
      361 aaaatggagt gacggtttca accaatgcga ctctaagaaa agatactcca atcgcagccg
      421 aagtgattta caaaccaaca gttgcggcag agcgtatcag ttcagacaag agcagtagct
      481 tggtagtcaa agaaggtttg gcagtcaaca gcattcatgc ggttaaagga gaaaactata
      541 caggtgacct agcttctcgt atccactata acgatggaca agacacaggt cttccagctg
      601 gttcaactgt tgaatggaag aacaaccaag cgccggacta caacaatgta ggaacaagtc
      661 gttatacact tgtagtaaac gttccaaatc aaggaactac agaaatagaa gtaccagtcc
      721 atgtttaccc aacagcaagc ttgaagaagg ctagctacac caataaacaa ggtactctgt
      781 caaatggaac agatgcaagt aagtatgttc aatttgaagg tagcgcagat acgccaaata
      841 acgtaacagt acgttggaaa gatggtgttc cagatgtctc tacagtctct gcagaccgta
      901 aggctaagat agaagttgtc tacccaggta atgcttcagc aacagataca gttgtgaaag
      961 aattagaagt atcacttcca acttaccatt caacagctaa gtctacagag tatacacgta
     1021 ccattggtga agcttacgct tcaaccgatg cgtcagacta tgtagaaacc actccaaaca
     1081 caccaagagg aacggaatat gcatggaaga cagatgaaac tggcaaccaa gcctatggct
     1141 catcaacttg gggaggggca aacggtgact ggctcggtaa gaagaccaat aaggttaaag
     1201 tttactatcc aaatgcggat ggtggcaatg agaaatctga agtcttggca gaagagacag
     1261 aggaaatcac tttcatcacc aaaccagcca aaccaagcat tacaagtgac ttgacatggg
     1321 caagtggtac tagaacgact gtcgaagttg gcaacgtgac aagcggtaca cgggtagtct
     1381 tgtatgatga gcaaggtaac gagctcggac atacagatgt agccaaagga gctaattacg
     1441 caactccaac cacagcaagt atcacaccaa ccaaggctct accgacaggt aaagtctatg
     1501 tgaagacgat ttacatgcca gacactgcag atcaacgtgt agagtcagag aaatcagatg
     1561 aagcgactgc taaaaccaat accctaacgg ctaaaggaat tatccaaacg ctggcaggcc
     1621 caggtaacat tggaggagtc ggcacgcttg atgcagctac tttaggtaag ttgttgagac
     1681 aagaaaatgg tggtacagac ttcacaggag cgactgcgga atggaaagat aagacaaact
     1741 tagagaaggg caatggagga agtcgagtag agcaccttct tgtccaacta aaaggacaca
     1801 gtgagaaaca agatgtggct atcacagtca caagtttgac tccgccaagt gccaaagcag
     1861 tcttgaaatc gaagggtgca gacttgacaa atgataactt ggcagattac gtaacagcag
     1921 agggacaagg taccctaagt tgggaaggta atccagccaa ggtagaagtg ggtcaagctc
     1981 ttccacgtat caaggttact tacccaacaa caggtgtagc tattactgac atcactgatc
     2041 aatatgtgga cgccaaagtc tacagtctcg aggctaacag taacgccaag acaagagtga
     2101 cggtgggaga cgcctttgac ccatcagcag gagactatgt tcaaacagtc gctaatacag
     2161 cagacttacc aagaactggc gtcagtcacg catggaaaga tggcaacaaa ccgacatcag
     2221 cgactgtagg aaaagccacc tacacagttg ttacaagttt tggtaatgat gcagacgtac
     2281 cagcagaact tcgaggacaa gatgtagaaa cgcaagtaga agtaacggtt ctctcaacca
     2341 aaccaagtaa accagaggcc agccaaaacc gtacggattt atcgataaca gtagtagtcg
     2401 gaaaagacga tgcgacgaag gcggaaatca cctttaaaga tgaactggat caagaacaca
     2461 cggtcagctt cactaaggga gccaatggtc aatgggacaa agatgatgcc aatagtcaac
     2521 caacggttca aatcatcaac aatgcagatg gaacagcgac agttcatatg acaggcggca
     2581 cagctaaagc aggcagcact gttgtaacga aacaacaaaa agccgattca gactttagtg
     2641 atatcagtga gttggttgta aaagaacact taaaaggtgc cacagtaact actaaggacg
     2701 atggttcagt agaagtggta gtaccaaaag aagcagatac tgcgacagtc agctatgtcc
     2761 cagaaggaca aacgcaagcg aaaacagtga cgattaccaa aggtcaagat ggcaactgga
     2821 caggtccagc cgattcagac ttagtgatta agaaagatga tgcgacaggt agagtcacag
     2881 tcactgtacc agcagataaa gtagccgatg gcagcacagt tacaggaaga gtagacagtg
     2941 ctactgggtt aagtccagaa gttgaagtga aagggaaagc gccacaacca tctgaattta
     3001 gtcatcatgt tcgagacaac ggcgacgaag tgattacctt gcctcagaat gcggacagcg
     3061 tgacgcttaa ctatccagta agcgacgcga acgtgaagac agttacgatt agtaaaggtc
     3121 aagatggcac ctggacagct ccagccgatt cagacttagt tgttaagaaa gatgatgcga
     3181 caggcagcgt caccgtcacg gtaccagcag ataagatttc gggtaaccga acgattacag
     3241 caagtgctaa agcaggaagt ggcgatggag aaagtaaaga acgtaccttt acaacaacag
     3301 ttgtagagcg tcaagcacca actgtttcag aagtgacagt agcagcgaat ggcacactaa
     3361 gtgcagaaca gatcaatgcg gctgttacag ctcctaagaa agttagtgcg gttgcggcag
     3421 aagccttgaa gcaagtagca gcaggcagta acacagagat tccagttaca gttacctatg
     3481 cggatggctc aacagaaacc gttcagttgg cagtatactc taaacaggta acaccaagta
     3541 cagtcggctt ccaacaaaaa ga
//
LOCUS       DAVDZK010000082         2995 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVDZK010000082 DAVDZK010000000
VERSION     DAVDZK010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2995
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.083"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(56..328)
                     /locus_tag="VUX16_002120"
     CDS             complement(56..328)
                     /locus_tag="VUX16_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8124998.1"
                     /translation="MFTTFFKKNQDNSDVFKKLIHRLSDMSVQDPEKIDRLLDIIFTP
                     DQGSEQLKTEATYREEILDDTLKEAKNQLHKEQLEKNLERFRKNSQ"
     gene            complement(366..749)
                     /locus_tag="VUX16_002121"
     CDS             complement(366..749)
                     /locus_tag="VUX16_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HET8124999.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFGNHQGGNDVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIQSSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            complement(746..979)
                     /locus_tag="VUX16_002122"
     CDS             complement(746..979)
                     /locus_tag="VUX16_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8125000.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGRERQFDESEFRKDEMSE"
     gene            complement(1030..2115)
                     /locus_tag="VUX16_002123"
                     /pseudo
     CDS             complement(1030..2115)
                     /locus_tag="VUX16_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
     gene            complement(2125..2766)
                     /locus_tag="VUX16_002124"
     CDS             complement(2125..2766)
                     /locus_tag="VUX16_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET8125001.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELSS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGELLVNQVQVWKSGLDDLDKATPKTLEESSSISSLPNTTTK"
BASE COUNT          872 a          573 c          453 g         1097 t
ORIGIN      
        1 atttgatacc accattataa catttagaaa aagcaaatgc accatttttg gtgcgttatt
       61 gactgttttt cctaaatctc tctaaattct tctccaattg ttccttatga agttgattct
      121 tagcttcttt taatgtgtcg tccaaaattt cttctctgta agttgcttct gtttttagtt
      181 gttctgatcc ttgatctgga gtgaaaatga tatctaacag tcggtctatt ttttcaggat
      241 cttggacaga catatcagat agtctatgaa ttagcttctt aaatacatca ctattgtctt
      301 ggtttttctt aaaaaatgtt gtaaacatct ataacctctc aaaaaaagca gcctatcagg
      361 actgcttagt gtaattccga aatcgcatca taaatggact gcaatttctt attgtcttta
      421 ttctttgtgt caatcaacgt atgtagctct tcaattttct tttgactact ttgaatatca
      481 ctattgttat ccgcaatcag tcttttaaga tgttgctgat aacttgtagt gatatctgtc
      541 tcttttcctg ttctaacctc tgtaactttg ggtttagaac tagaatttga ttccgtcaca
      601 ggtgcttgtt tgcgcttttg aaaagccgct tcataattta catcattacc tccttgatga
      661 tttccaaata aggccgcaat tttatctgga tcttcttgat tttctgattt actttctaat
      721 ggttgattaa aattccaatc ttttgtcatt cactcatttc atcctttcta aattcagatt
      781 catcgaattg tctttctcta ccgaaggcat ggtcaagagc ttcttcaaaa ctcatgtgac
      841 taatgctttg acgccttttg aacgtcgcaa acatcgctgt ctccagttgt tctttgtaag
      901 cagcgagttt ttctgtctct cttgctacct tactttcttg cctagtgacc ttttcttcta
      961 agcgttcaat aatggtcata tacgatcctc cttcattcta atattagcta aaacatcttg
     1021 attttgttat cacaattcta aacattgaga ggtttttctt actggttgat tcctcaatgt
     1081 ctcttttgca ttctcgatca tcaattgtaa atctgatttc ttttctctaa ggacatcatt
     1141 ccagtctact ttttctttcc cagatttatt atcagggaaa tccaggaaaa caggaaatcc
     1201 tgattgagat aacttatcag aaaaatcttt tcctgcatca tcacaatcta ccgcaagtgt
     1261 caataaatca ggatgattat caaaatagct ggtggtatca cgaattgtat tgattaaagg
     1321 caataacttt gaaggtatta ctgtatccaa aaattccaac ttctgatttt cttcagctat
     1381 cagtcgtaaa atttgataag caacaacaga cctttttaat ccttccatag ataccaaacg
     1441 aacatcagat agactttgtt gatgaagttc gtaatagctc attaagtcga tgaacgattc
     1501 acaaaagacc agtctattag gtttaccaat atcaaaggat attccaacat gtccatggct
     1561 tccttttaga atcgttttta acctctctct aggaagagag tgattcttat aaatccctta
     1621 gagacttgct gcctgcagct tgtaacgatg atcaaagctt ttaaaaacaa taacaggttc
     1681 aacagtttca tttgttttcc agctagcttg tgctatcaaa ccttgttgaa tcatcttttg
     1741 aacgatttct tctgaaattc ctctacattc tgttaaataa tatctagcca gactgcagtt
     1801 agaatcttct actctcttta aaggataata aaatggtctc tctctttttt cttgaacagc
     1861 ttctttttga aaaggttctt cagaaagaaa ggctagagct tctttaaagg aaattccctt
     1921 aacaagtcga acaaaatcaa tgacatcacc ttgaatatct cttgaaaacc atttaaaagt
     1981 attggtagtt gaaaaaatcc gaaatgaatc gtgttcagga tgttcataga cacggctaga
     2041 aacttgttta aaggagatac ctaaacgatt ggctacatca agaattgaaa tttgcttaca
     2101 ttcttctatt tccatgcaat atcatcattt tgtcgtagta tttggcagtg atgatattga
     2161 tgatgattct tctaaagttt taggagtggc cttatccaaa tcatctaacc cagatttcca
     2221 aacctgtact tgattgacca ataactcacc tggtagtttc gaataagaca acttaaccgt
     2281 tctggtttct gtctgattgg tctttgattg gttggcattc tttaaatcag atacataggt
     2341 tacattataa gagaccatgg caatggcttg attcgtagtc tgattgacaa agatatcagc
     2401 tttttcaaaa tgataatcta aaatataatc cttatacact tggttcatgg catcattttg
     2461 acttgacaat tcttgagaat aagccgattc agtcatataa ggttgaatac gtgtattatt
     2521 ttctccgagc ttttctttcg tatagtactg cgtcaaaaat tcttttacag tatccgatga
     2581 caaaatgctg gctttatctt ctgcttgttt atcctctaca agtttagctg cagccaattc
     2641 aatctcttta cgactttgtt tagcagtcga gtgttgacca gcagtatatc ccatcatgag
     2701 aataaagcta gttgcagcca ctgctccaac actaattaag gctttagttt tgactttatt
     2761 taacatctta gaccttcttt ctataaaaac taggtcaaga atagcagata aatcttgaaa
     2821 aaagtatcac agaagtaaaa atgccacccg aaggtggcca atataactta caaaattagt
     2881 aatccgtctg ataaagtttt ttatacaaac catttttcat attcaatagt tctgtatgac
     2941 ttccttgttc tacaatttct cctcgtaata tataatcatg gggatatttc aatcc
//
LOCUS       DAVDZK010000083         2991 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVDZK010000083 DAVDZK010000000
VERSION     DAVDZK010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2991
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.084"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(175..864)
                     /locus_tag="VUX16_002125"
     CDS             complement(175..864)
                     /locus_tag="VUX16_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473604.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET8125002.1"
                     /translation="MKGCYAHVWKKHRDNGEKNYRYSICKYHFGAASVAVVALMFFAN
                     GAVAASETITPKTAGDVVKADSDSNADGNPESSDEGDSKKALTDQPAELKSADEPKGQ
                     EAPVEESDSVQAAAESKTTGVESNSAQPETNPAPQAEGEGKQDQSTPVANRTAAESIQ
                     STLEALLANLTLDSMKALHTEVEEGLAKAKTVLENPKATQAQVDEQVKLMEDLTRRVR
                     EACLLRFFFLK"
     gene            complement(1246..1709)
                     /gene="tnpA"
                     /locus_tag="VUX16_002126"
                     /pseudo
     CDS             complement(1246..1709)
                     /gene="tnpA"
                     /locus_tag="VUX16_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(1981..2190)
                     /locus_tag="VUX16_002127"
     CDS             complement(1981..2190)
                     /locus_tag="VUX16_002127"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8125003.1"
                     /translation="MFSQLRMREEQALLAQDYALETARVEGIEQGLERGKLFAFLDMV
                     RQGLLTPEVASEQLCMTVAEFEEFL"
     gene            complement(2183..2299)
                     /locus_tag="VUX16_002128"
     CDS             complement(2183..2299)
                     /locus_tag="VUX16_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET8125004.1"
                     /translation="MVGVFRQQALYPATRASHQPSRPTAGLQELVRGGQENV"
     gene            complement(2345..>2991)
                     /locus_tag="VUX16_002129"
     CDS             complement(2345..>2991)
                     /locus_tag="VUX16_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET8125005.1"
                     /translation="QREGDTHHSYKHIAPVYAIAIVDSNYFQDDFAFHSFSMSEDTIG
                     EVLTITTNGQENHLVKMAFLELKKYRETSKDEVRKPWLEFFGNKPFTQEPERAISQAD
                     QLLDYKSWSEEDRKMFSQLRMREEQALLAHDYALEQAEEKGLERGRAEGLERGRAEGI
                     EQGIEKGLEQGLERGKLFAFLDMVRQGLLTSEVASEQLGMTVAEFETLLKKHHK"
BASE COUNT          788 a          686 c          538 g          979 t
ORIGIN      
        1 taaatatttt agtatttaag gaaaagatat gtttttttct ttttgttccc tagcttgtca
       61 aaagacaagt tttgagacag tattattata tactattttt acaaatttga acagcaaaac
      121 gctaactttt ttcagccgtc ttgtcactta tttttatagg tggtttttga gctgctattt
      181 cagaaaaaaa aaacgaagca agcaagcttc cctgacccgg cgagtcaggt cttccatgag
      241 tttgacttgc tcatcaacct gtgcttgcgt cgcttttgga ttctctaaga ccgtcttagc
      301 ctttgcgaga ccttcttcca cttcagtgtg aagagccttc atggagtcta aggtcagatt
      361 tgccaacaaa gcttctaggg tgctttgtat cgattcggct gctgtcctgt tggcaacagg
      421 agtcgactgg tcttgttttc cttctccctc tgcttgagga gccggatttg tctctggctg
      481 agcagagtta gattctactc cagtcgtttt agactcagca gctgcttgta ctgaatcgct
      541 ttcctcaact ggcgcttctt gccctttcgg ctcgtcggct gatttgagtt cagctggctg
      601 gtcagtcaga gctttcttgg agtctccctc atccgaggac tctggatttc catctgcgtt
      661 gctatcagag tcagccttaa cgacatcacc tgccgttttt ggagtaattg tctcactcgc
      721 cgccacagcc ccattcgcaa aaaacatcaa ggccacaaca gcaacgctgg cagcaccaaa
      781 gtggtactta caaatggaat aacggtaatt tttttcacca ttatccctat gttttttcca
      841 aacatgagca tagcatcctt tcattgtatc acaggtcaac tttcctcaaa agagtacaca
      901 aaaacccgta acagataata tgtcaacttt atagtaatac ttttctagaa agaaatcaag
      961 tataaagcta gatgaagata agattagcat aagattaaaa atgcagcaaa aacaccgata
     1021 taacaacatt tttctgtaat tatatatata tgcacacctt tatataacaa tcttattatg
     1081 gataatattt taaatttaat ataaatcatg accacccgtc taacgggtgg tttgtaccag
     1141 ggctataagc ccaattacca gccagcgcct aaagacgctg gctttcactt tgttcaatcc
     1201 ttattgctct tgactcgtca cttgcctctt aaagaggctt tggtattact taccactatc
     1261 cctaaaggga tcctcatatt cttttacatt caatttatct agtgctatat catgcttttc
     1321 ctgttctggt atatatttct taattgtagc ttcattgact cccaccgtac tcacataata
     1381 accttccgcc cagaaatgcc gatttccaaa tttgtacttg agattggcgt gtttgtcaaa
     1441 catcatgagt gcactttttc cttttaaata acccatgaaa ctcgaaacac ttatactagg
     1501 tgtaatactt actaacatat gtacatggtc tggcattaag tgaccctcga taatttcaac
     1561 tcctttataa ctacacaagc gatgaaatat ttcgcctaaa ctacttcgat attgattata
     1621 gataactttt cgtctatact taggggtgaa cacaatgtga tagaacagtg ccactttgtg
     1681 tgcgataaac tatgagcctt ttgtgccatg tttttctcct ttcgctttac aattggcttg
     1741 aacaccttta ttgtatcgcg tttggagttt tttgggtata accttcgacg cgcacctaac
     1801 ggagcgagac ggactaatag tcacataata aaaaacagat tctatctata gaaagataaa
     1861 atctgccatt ttttctatat aaaatcagca aatccattct gctgaaaatc gtgaaatatg
     1921 atgtgaattt ccgaccactc tgacaggatt ttgagggaaa agctagatat attccctaac
     1981 ttacaaaaac tcctcaaact cagcgacagt catacacaat tgctcactcg caacctcagg
     2041 tgtcagaaga ccttggcgaa ccatatctaa gaaggcaaaa agttttccac gttctaaacc
     2101 ttgttcaata ccttcgactc tagctgtttc caaggcatag tcctgtgcta ataaggcttg
     2161 ttcttctcgc atacgtagtt gactaaacat tttcctgtcc tcctcggacc agctcttgta
     2221 atccagcagt tggtctgctt ggctgatggc tcgctcgggt tgctgggtaa agggcttgtt
     2281 gccgaaaaac tccaaccacg gtttgcgaac ctcgtctttg ctggtttctc tgtattttta
     2341 ggtcttattt atgatgtttt ttcaatagtg tctcaaactc agctacggtc atgcccaatt
     2401 gttcactcgc aacctcagat gtcagaagac cttggcgaac catatccaga aaggcaaaaa
     2461 gttttccacg ttcaagtcct tgttctaaac ctttttcgat accttgttca atcccttcag
     2521 ctcgtccacg ttcaagtcct tctgcacgac ctctctccaa ccctttttcc tcagcttgtt
     2581 ccaaggcata gtcatgagcc aataatgcct gttcttctcg catacgtagt tgactaaaca
     2641 tttttctgtc ctcctcggac cagctcttgt agtccagcag ttggtctgct tggctgatgg
     2701 ctcgctcagg ttcttgggta aagggtttgt tcccgaaaaa ctccaaccac ggcttacgaa
     2761 cctcgtcttt gctggtttct ctgtattttt ttagttccaa gaatgccatc ttgaccaaat
     2821 ggttttcttg accgttagtt gtgatagtta agacctcacc tatcgtgtct tcgctcatac
     2881 taaaactgtg aaaggcaaaa tcatcttgga agtaattact atctacgatg gcaatagcat
     2941 aaactggtgc gatatgtttg taactatggt gtgtatcacc ttctcgttgg c
//
LOCUS       DAVDZK010000084         2783 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVDZK010000084 DAVDZK010000000
VERSION     DAVDZK010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2783
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.085"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            45..1049
                     /locus_tag="VUX16_002130"
     CDS             45..1049
                     /locus_tag="VUX16_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET8125006.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKNEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKVYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLVSVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            1118..1984
                     /locus_tag="VUX16_002131"
     CDS             1118..1984
                     /locus_tag="VUX16_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET8125007.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGIKQIQDVLPFDSDLNRLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            1981..2739
                     /locus_tag="VUX16_002132"
     CDS             1981..2739
                     /locus_tag="VUX16_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET8125008.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSSEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGQIIQDLNQEEKAKMKISDYYQLFE"
BASE COUNT          865 a          486 c          615 g          817 t
ORIGIN      
        1 ggattgaaat atccccatga ttatatatta cgaggagaaa cagaatgaaa aataaacgtt
       61 taattggaat tatcgctgca ttagcagtct tagtagcagg aagcttgatt tattcttcaa
      121 tgaataaatc agaagctcag aataataaga atgagaagaa aataaccaag attggtgtgc
      181 ttcaatttgt gagccatcca tcccttgatt tgatttataa agggatccaa gatggacttg
      241 cagaagaagg atataaagat gatcaagtta aaattgattt tatgaactca gaaggtgatc
      301 aaagtaaggt tgcgacaatg agtaaacaat tggttgcaaa tgggaatgac cttgtggttg
      361 gtatcgcaac accagcagcc caagggttgg ctagtgcaac aaaagaccta ccggttatca
      421 tggccgctat tacagaccca attggtgcta acttggttaa agatttgaaa aaaccaggtg
      481 gcaacgttac aggggtatct gaccacaatc cagctcaaca acaagttgaa ctcatcaagg
      541 ctctgacacc gaatgtgaaa acaatcggag ctctttactc aagtagcgaa gacaattcaa
      601 aaacacaggt cgaagaattt aaggtttatg ctgaaaaagc aggtctgaca gtggaaacat
      661 ttgcagttcc ttcaacaaat gaaattgcct caactgtcac tgttatgact agcaaggtag
      721 atgctatttg ggttccaatt gataacacca ttgcatcagg atttccaacg gttgtctcta
      781 gcaatcaaag ttctaagaaa ccaatttatc ccagtgcgac agctatggta gaagtaggtg
      841 gtttggtatc agttgtaatt gaccaacatg accttggtgt agcaacaggt aaaatgattg
      901 tgcaagtctt gaaaggtgca aaaccagccg ataccccagt caatgtcttt tcaactggta
      961 agtcagtcat caataaaaaa atagcacaag aactaggtat tactattcct gagtctgttc
     1021 tcaaagaagc aggacaagtc atcgaataaa taaggtaggg aggaggagac tctttccatt
     1081 ttttaaaaag atgaatatag aaaggattaa ataaaatatg attgtttcca ttatttctca
     1141 aggatttgtc tgggctattc taggtctggg aatctttatg acatttagga ttttaaactt
     1201 tccagatatg acgacagaag gttccttccc tcttggggga gctgttgctg tcactttgat
     1261 aaccaaaggc gtgaacccat ttttagcgac acttgttgct gtaggagcag gttgtttggc
     1321 tggaatggca gcaggccttc tttatacaaa agggaagatc ccaaccttgc tctcagggat
     1381 tttggtgatg acttcttgtc actcaatcat gctcttgatt atgggacgtg cgaatttagg
     1441 cctgcttgga atcaagcaaa ttcaggatgt tttgcctttt gattcggatt tgaatcgact
     1501 cttgacaggt ctcatctttg tgagtattgt tattgctctc atgctctttt tcttggacac
     1561 taaactcgga caagcctata ttgctacagg ggataatcct gatatggcta gaagtttcgg
     1621 gattcatact ggacgcatgg agctcatggg cttggtctta tcaaatggtg tgattgccct
     1681 tgcaggtgcc ctcattgctc agcaagaagg ctatgccgat gtgtctcgag ggatcggggt
     1741 tatcgttgtg gggcttgcaa gtttgattat tggagaagtt attttcaaga gtttgagctt
     1801 ggcagagcgt ttggttacta tcgttgtagg ttctatcgct tatcaatttt tagtgtgggc
     1861 agttatcgca cttggcttta atacaagtta ccttcgttta tacagtgcct tgattttagc
     1921 agtctgcctc atgattccaa catttaagca aacaatcttg aaaggagcca agttaagcaa
     1981 atgacagcaa ttgtagaatt aaaaaatgca accaaaatcg ttaaaaatgg ctttgatgaa
     2041 gaaaagatta ttttaaatga tgtttcctta gaaatttttg aacgggactt tatcacgatt
     2101 ttgggcggaa atggtgctgg aaaatcaacc ctctttaaca ctatagcagg gaccttatca
     2161 ctaactagtg gaactatccg tattttaggt gaagatctca ctaagttttc atccgagaag
     2221 cgtgccaagt acctgtctcg tgtcttccaa gatccaaaga tgggaacagc tccccgtatg
     2281 acggtcgctg aaaatctttt aatcgccaag tttcgtggtg aaaagcgtgg attgttacca
     2341 cgacgcttga ctagctataa ggatgaattt caggcaacca ttgaaaaagt aggaaatggt
     2401 cttgagaaac acttgaatac accgattgag ttcttatcag gtggacaaag acaggctttg
     2461 agtctcttga tggcaacctt gaagcgacct gaattactct tgttagacga gcatactgca
     2521 gctcttgatc caaagacaag tgttgccctc atggaattga cagatgaatt tgtcaagaag
     2581 gatcaattga cagcgcttat gattactcat catatggaag atgctcttaa gtatggcaat
     2641 cgcttaattg tcatgaaaga aggacaaatt attcaagatt tgaaccaaga agaaaaagca
     2701 aaaatgaaaa tctctgatta ttatcaacta tttgaataaa gtagggaaaa tgagtgaaat
     2761 ggtttacttt ttttctgaaa taa
//
LOCUS       DAVDZK010000085         2745 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVDZK010000085 DAVDZK010000000
VERSION     DAVDZK010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.086"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            706..2628
                     /gene="ltrA"
                     /locus_tag="VUX16_002133"
     CDS             706..2628
                     /gene="ltrA"
                     /locus_tag="VUX16_002133"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET8125009.1"
                     /translation="MTKPKNDDKLLKHQKLRYAEYYGMTEIFDDLYSKSQNGFSFKNL
                     MNIITSPENILLAYRTIKRNGGSQTEGVDGVTIKDLENLTQEDFISKVQRRFQYYRPR
                     KVRRVEIPKPNGKKRPLGIPSMWDRVAQQCILQVLEPICEAKFYKHSYGFRPLRSADN
                     AIMDCMYRMNKSHMTYVVDVDIKGFFNEVNHTKLMRQIWTLGIRDKQLLVIIRKMLKA
                     PIVLPNGKVTYPTKGTPQGGILSPLLANINLNEFDWWIGRQWEERDCKELVPQYNSKG
                     TRHKSHVYRKLRTSTTLKEVYIVRYADDFKIFCRNRNEAERTFKAVKLWLKERLNLPI
                     SEEKSQITNLRKKSSEFLGITLKLVSKNNRLVCFSHIASKAKKRIKHQLKQQMKLIQI
                     KGAKETIIREIQKYNSMVIGIHNYYSMATHVSKDLEEIHYQLYLSFKNRLQAKGLTKI
                     GEYKGKDKGLLPYLQSQNIRYLMGYPILPISYVKTRTLKGRNKNLNRYTPEGRKLIHK
                     QQESVETWKLKWLREHSIINKRATVEYNDNRISLFVAQKGKCAVTGQELDMDDIHCHH
                     KRPWLETKDDSYRNLIIVGRDIHRLIHATNEKVIKNLFQLLNLSDTGLTKLNQLRELA
                     GNSPLLKENLNLEQLC"
BASE COUNT         1004 a          425 c          577 g          739 t
ORIGIN      
        1 aaaaggttag acacgttctt gaaaaatcaa cctgataatc aggttaaatt tgaatagaat
       61 ggagaactct tatcttgaaa attggaatga aggggtaacg ccctgaaacg atttctctaa
      121 tactccgaca tgcgtttatc ttgtgcaaag gtaaaggttt gaagctcggt gaagtcggct
      181 gaaagatacc gtcattctta aggacttaag aatcgaaagt gttccagagg tggaatatgt
      241 atctgatagg tcgggagtca ttaaaaacta aatagggtga gaatgtgcat gagcactgac
      301 gaaccagcga atgtacgctc cgaaggcgag tacgtagaaa tgcgtataac aacgtaagtt
      361 gtttcaactt gaggaagagt aagaatcgac gatatgaaat tccttgttat gttacaggca
      421 tatcaaagtt gaaggggtat agctaggcac ctaagtttag tattgataaa gataagggaa
      481 cgtcgaaagc tagagatgtg gaggttgcac aaccagagaa acattggaaa gaaaatcata
      541 actttcctta atctctagtg agagtggtgg cacgaccttt gaaagtgttg taatgatact
      601 ggaggaacag ccactagtca atagtgtatt gttatgaact ttatcatttc atggattctt
      661 gtaagacata aaaggtcacg aatccaaaga gaggagtgat agaccatgac gaaaccaaaa
      721 aatgatgaca aactattaaa acatcaaaaa ctaaggtatg cggaatacta tggcatgacc
      781 gagatatttg atgatttata ttccaaaagt caaaatggat tcagttttaa gaacttaatg
      841 aacattatca catctcccga gaatatactg ctcgcttatc gtaccataaa gcgaaatggt
      901 ggtagtcaaa ccgaaggagt agatggtgtt accattaaag atttagaaaa tctgacccaa
      961 gaagacttta tctctaaagt tcaaagaaga tttcaatatt atagacccag aaaagtcaga
     1021 agagtagaga ttcctaagcc aaatgggaag aaacgaccac ttggcattcc ctcgatgtgg
     1081 gacagagtag ctcaacagtg tattttacaa gtgttggagc caatctgtga agcgaaattt
     1141 tacaaacaca gttatggatt tagaccctta aggtcggctg ataacgctat tatggactgt
     1201 atgtatcgta tgaataaaag tcatatgact tatgtcgttg acgttgatat taaaggcttt
     1261 tttaatgaag tgaatcatac taagttaatg cgtcaaatct ggacattagg tatcagggac
     1321 aaacaacttc tagtgattat tcgaaaaatg ttaaaagcac caattgttct tccgaatgga
     1381 aaagtgacat atccaactaa gggcacacca caaggaggta tcttatctcc actacttgcc
     1441 aatatcaatc tcaatgaatt tgattggtgg ataggacgac aatgggaaga aagagattgt
     1501 aaggaattag ttcctcaata taattccaag ggaacaagac acaagtcaca tgtttacaga
     1561 aagctgcgaa cttcaacgac gctaaaagaa gtttatattg tccgatatgc ggatgatttt
     1621 aaaatctttt gtcgaaatag gaatgaggca gagcgaacgt ttaaggctgt aaaattgtgg
     1681 ttaaaagaac gacttaacct ccctatttca gaggaaaaat ctcaaattac caatctgaga
     1741 aagaaaagca gtgaattcct tgggattact ttaaagctag tttctaagaa taatcgtttg
     1801 gtttgtttct ctcatattgc atcaaaagcc aagaaacgta ttaaacatca actgaaacaa
     1861 cagatgaaat tgatacaaat taaaggtgct aaagaaacaa ttattcgtga aatacagaag
     1921 tataatagta tggttatcgg tattcataac tattatagta tggcaacaca tgtgagtaag
     1981 gatttagaag aaattcatta tcagctttat ctctctttta aaaatagatt gcaggcgaaa
     2041 ggtctgacaa aaataggaga atacaaggga aaagataaag gacttctccc ctacctccaa
     2101 tctcaaaata ttcggtactt aatgggttat ccaattcttc caattagcta tgtcaagacg
     2161 agaacactaa aaggaagaaa taagaatctg aataggtata ctcccgaggg gagaaaattg
     2221 attcataaac aacaggaatc tgttgaaaca tggaaattaa aatggctgag agaacactca
     2281 attataaata agcgtgcaac agttgaatac aatgataatc gaatttcttt atttgtagct
     2341 caaaaaggga aatgtgctgt aaccggtcag gaattggata tggatgatat tcattgtcac
     2401 cataagagac cgtggttaga aacaaaggat gactcttata ggaaccttat cattgttgga
     2461 cgagatattc atcgcctgat tcacgcaaca aatgagaagg ttatcaaaaa tctctttcag
     2521 cttttgaatt tgagtgatac aggactgacc aaattaaatc agttgcgcga acttgcagga
     2581 aattcaccat tattgaaaga aaatttgaac ttagaacaat tatgttaatc atattaatac
     2641 agcacgataa agcaaaatcg tgataataca ctattgatgg aacgccgtgt gcggtgaaag
     2701 tcgcacgcac ggtgtgaagc gggggaaaag atggagatag tatca
//
LOCUS       DAVDZK010000086         2689 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVDZK010000086 DAVDZK010000000
VERSION     DAVDZK010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2689
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.087"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..636
                     /locus_tag="VUX16_002134"
     CDS             <1..636
                     /locus_tag="VUX16_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET8125010.1"
                     /translation="FEEGKIKKKDLEISIVSKEDDNSYYEEVPCEIPESWEWVRLNDI
                     TSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDL
                     MWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQS
                     VIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            693..1490
                     /gene="psrA"
                     /locus_tag="VUX16_002135"
     CDS             693..1490
                     /gene="psrA"
                     /locus_tag="VUX16_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HET8125011.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLTFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1501..2106
                     /locus_tag="VUX16_002136"
     CDS             1501..2106
                     /locus_tag="VUX16_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET8125012.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSINTGLSYKKGD
                     LSINNKGIRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKIEKLFEKVNQLWK"
     gene            complement(2054..>2689)
                     /locus_tag="VUX16_002137"
     CDS             complement(2054..>2689)
                     /locus_tag="VUX16_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET8125013.1"
                     /translation="FEEGKIKKKDLDISIVSQGDDSSYYGNKDETSSYPIYEIPEAWR
                     YIKFASLVNFRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKK
                     IDISPKGTLLMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLIS
                     TLGDSKDAIKGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQFFE"
BASE COUNT          927 a          390 c          458 g          914 t
ORIGIN      
        1 tttgaagaag gcaagatcaa aaagaaagat ttagagattt caattgtttc caaagaagat
       61 gataactctt attatgagga agtaccttgt gaaataccag aaagttggga atgggtgagg
      121 ttaaacgata taacctccta cattcaaaga gggaagtctc caaaatattc aaatattcct
      181 atataccctg tgattgctca gaaatgtaat caatggtctg gcttttctat tgacttagca
      241 agatttattg atcccgaaac agttcatagt taccagaaag aaagattact aagagatggt
      301 gatttaatgt ggaattcaac aggtctaggt acgttaggac gattagctat ttaccatgaa
      361 aataaaaatc cttatggctg ggctgttgca gatagccatg ttacagttat aagagtctta
      421 tcgggagtta ttaattgcca tttcatctat aattttcttt cctctcctat tgttcagtca
      481 gttattgaag aaaaagcgtc gggtagtaca aaacaaaaag aattattaac gaaaactata
      541 aaagaatatt taatccccct cccacccctt cctgaacaat ccagaatcgt tgataaaatc
      601 gaacaatttt tcgcccatat tgacgcacta atttagtata atagttttac gtgcggtgga
      661 atttctatca aacataagat aggagtttta cgttgaaaga ttttgaatta catttgaaga
      721 aagctggttt agctgaaaat actgtgcgtt cgtaccttta tggtgttcga tttttcttgg
      781 agaattacga actcaaaatg gaagatttat ttgaatacaa aggatattta ttagacaatt
      841 ttaaacctaa aactgtcaat ttgcgactac aaggagtaaa taaatatctg acttttattg
      901 gtcatgatga tttgaaatta aaatttgtca aagtacagca aaaaccgttt ttagaagatg
      961 tcattagcca cgctgattac ctttttctta aacgtagttt gaaaaaagat ggtattttaa
     1021 aatggcattt tgtcgtttgg tttttaggtg caactggggc tcgtgtaagt gaacttatta
     1081 aactaaaagt agagcatgta gaaatcggtt attttgacat ttactcaaaa ggtggtaaaa
     1141 ttcgtagact gtacattcct aaaaaattaa gaaatagttg tcttagttgg ttagaatcag
     1201 aaaatcgccg aagtggttat ttatttttga ataaatttaa cgaaccaatt acagcaagag
     1261 gagttgctca acagttaaaa aattatgctg ataaatacaa aatgaatcct aaagtaattt
     1321 accctcattc ttttaggcat ttatttgcta agaatttttt agcgaagtat aatgatattg
     1381 ccttgcttgc agatttgatg ggacacgaaa gtatagaaac tactcgaatt tatctaagga
     1441 aaacagctac tgaacaacaa aatattgtag ataaaattgt taattggtaa aaaataacag
     1501 gtggtcaaac tgactacctg ctatttttgt gattatggct cttattatgg gaatatacct
     1561 atgaattggg ttgttataaa aataaaagat attttttcaa taaatacagg tctttcttac
     1621 aagaagggcg atttaagcat taataataaa ggtattagaa ttatacgtgg tggtaatatt
     1681 aagcctttag aattttctct gttggataat gattactaca ttgatacaca attcatctcc
     1741 tctgagcaag tttatttaaa acataatcag ctaataacac ctgtatcaac ctctttagaa
     1801 catattggaa agtttgcaag aatcgataaa gactatgatg gtgttgtggc tggtggattc
     1861 attttccaat taacaccatt cgaaagttca gagattattt caaaatttct attatttaac
     1921 ttgtcctctc cgttatttta taaacaattg aaagcaataa ctaaactatc aggtcaagct
     1981 ttatataata ttcctaaaac tacactaagc gagctattaa ttccgttagc tccttttgag
     2041 gaacaggaac ttattactca aaaaattgag aaactttttg aaaaagtaaa tcaactttgg
     2101 aaatgattct tttcatctct tcatgattag aaatagggat taataattcg gagatactgg
     2161 tactatttaa tgttttccct ttgatagcat cttttgaatc acctaaagta gagataagtg
     2221 gcaaaaatat cattaagtaa tctctgataa tattttcttt attagcatag gggaatatcg
     2281 atataatggc ttcattatga gtggcaggaa tatccaatat ggcaactttt ccaatagata
     2341 atttaaagct cattaataaa gttcctttag gtgaaatgtc tattttcttt gattttaatg
     2401 ctaatttaga aatagattct ctcgtattag ttacataacc agatataggc atatctgata
     2461 tagataccca gggtatttca gttccccaaa aagtagcttc actgcgtgga ggagtttttc
     2521 ctattctgaa gttaactagg ctagcaaatt taatatatct ccatgcttct gggatttcat
     2581 atataggata agaggatgtt tcgtctttgt tcccataata agagctatca tctccttggg
     2641 aaacaataga aatgtccaaa tctttctttt taatcttgcc ttcttcaaa
//
LOCUS       DAVDZK010000087         2255 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVDZK010000087 DAVDZK010000000
VERSION     DAVDZK010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2255
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.088"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..235
                     /locus_tag="VUX16_002138"
     CDS             <1..235
                     /locus_tag="VUX16_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET8125014.1"
                     /translation="GIQASMSRKGNSQDNGRMESFFGILKSEMFYGYEKTFKSLNQLE
                     QAIIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(351..1154)
                     /locus_tag="VUX16_002139"
     CDS             complement(351..1154)
                     /locus_tag="VUX16_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET8125015.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1433..2188)
                     /locus_tag="VUX16_002140"
     CDS             complement(1433..2188)
                     /locus_tag="VUX16_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET8125016.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
BASE COUNT          745 a          442 c          346 g          722 t
ORIGIN      
        1 gggaattcaa gcatccatgt cacgtaaggg aaacagccaa gacaacggta ggatggaatc
       61 tttctttggc attttaaaat ccgaaatgtt ttatggctat gagaaaacat ttaaatcact
      121 taatcaattg gaacaagcca ttatagacta tattgattat tacaacaata aacgaattaa
      181 ggtaaaacta aaaggactta gccctgtgca atacagaact aaatccttcg gataaattaa
      241 ttgtctaact gtttggggtc agtacatttt aacacttgat actatgcgtt ttattgtggg
      301 aatgtttact tcattttttc ctaaaattca atgtttactc agtatttgga ttatgaaaaa
      361 tcgaggtcta aatctagata cattttttct gaagacaaat cattttgacc accgagcaag
      421 agattttcaa aaaaagctgt taaaaactca ggacgtcgct gtaaaatctt tgcattatct
      481 aataccaagg catcacgaaa atacttggaa tgttgctgaa atggtatatt atcaatatca
      541 aaaccaaact cacgaagata ctgaatcaaa aagaccgtta ctgtccgagt gtttccttcg
      601 cgaaatggat gaatctgcca gattcctgaa ataaaatgct ggatttgttt aaccacatcc
      661 gcctgagtta gtgtcgcata tgcaacttgt ttttcctgat taaaatcata atctaaggtc
      721 atttgaatca tggagtaatc agagtacaca acactttcac cattcaaaac aggttcattc
      781 tttgtgatat tggtctgacg aaattgcccc accggaatag agggttcaaa tatatcttga
      841 aacaactcct tatgaatagc aagtaaggtc gcaggactaa agctaaagcc tcttcgagac
      901 aatagttcta caatacgtag agaaaccaag tctgcctctt ccgtacttgc atcaatagta
      961 tggtgataag ccgttgcatc ctcataaacc tgctcataag tcagttctcc ccgggactgt
     1021 ttctcagcca aagattccat atacgctgat ggcactagat tgtcaacttt ctgcagacca
     1081 aaacctatcc gccataaatc acgcttcgct tcataagaca agtttggatt gtcaatgttg
     1141 taagttggtt gcatagaaat atcctttcaa ttgtttttct tcattaccag taaatcacga
     1201 aattggttgg aaactggctt aaactataaa aagtcctcac aataggttct atgatatata
     1261 tatatatact tcatgtaaat aataaaagag ttataatcag cactactgat aaattcaata
     1321 ccgatttcgc catcttaaaa cttagtcaaa cgaataccgt tgatttccag ttcattaagt
     1381 cgttgacctg tcaagacttc tcgttccttc aactggaaaa gttaaggggg aactaataca
     1441 aatcctctac gcttctatat tcaatgattt catttttgat aatattcttt ttaaactcaa
     1501 aatgttttaa aggattatcg attaacacta actttggaat atcatctaga tttgtgacca
     1561 aggataaaat aaaatccgat tgaaactcct tgactttttc aaattctttt gcagttaaac
     1621 gcacacgccc cttagatttt cggatacctt ttacttcggc aaggtaagaa tactcttgga
     1681 catctacctg aaagtcatat ccatcaccat aaagacgggc atcggttaac tgtccacctt
     1741 ggaatttttc ttctttatca aaatgaagga taaaataatt ctcagcctcc attcccgttt
     1801 cctgtagacg tttgaattta gttcgaacta ttggtttttc aacgatggtt atgcctgttt
     1861 tcttcccttc actggcaagt aacattttaa ctatttcagc ataactatga acatcttcat
     1921 ttccaaacat catatcaatt aaatctttac gaaaacgata aacttcagct ttctgccacc
     1981 aaccttttcg attattgtca aaataaggat caaataaatc cattctattt tttacaactc
     2041 cagttgtttc agcaattccc agagaaacca catagcgata aaactccgac ttgctagagc
     2101 attgaaattc ttttataaaa agcttgtcaa acttggcaag accgtagcca attaaattta
     2161 acaattcata atgagggtgt ttggacatca ctttctccat caatagatat tgatttcatt
     2221 ataccaaaaa acacggcatt acaccatgtt tctat
//
LOCUS       DAVDZK010000088         2055 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVDZK010000088 DAVDZK010000000
VERSION     DAVDZK010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2055
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.089"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..452
                     /locus_tag="VUX16_002141"
     CDS             <1..452
                     /locus_tag="VUX16_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET8125017.1"
                     /translation="EEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLIAVF
                     CAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKEHWISYQKTAQLLEKEKFLYQCQT
                     EKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASAEAPGKKE"
     gene            465..1073
                     /locus_tag="VUX16_002142"
     CDS             465..1073
                     /locus_tag="VUX16_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8125018.1"
                     /translation="MFQSSYLLPLLWLKKEADKEKMSATQCQIFFFYYQLFELLFARE
                     SDLKDLCLGGQGFYFSQLEKDLLSGVSRFLTNLEGKGTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQAVERLETPLLLSFQDRQDLMWIYQSALEKDYSVKVIGDKHFVL
                     KRQDATKLTGRQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            1144..1476
                     /locus_tag="VUX16_002143"
     CDS             1144..1476
                     /locus_tag="VUX16_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8125019.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEVLDHLVQPQLISLNKSEF
                     MQLNSGTY"
     gene            1487..>2055
                     /gene="ply"
                     /locus_tag="VUX16_002144"
     CDS             1487..>2055
                     /gene="ply"
                     /locus_tag="VUX16_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET8125020.1"
                     /translation="MANKAVNDFILAMDYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQ"
BASE COUNT          632 a          382 c          467 g          574 t
ORIGIN      
        1 cagaagaaat gtacctgaca gagcgattag acgtacagat agctcatttt ttaaagaaaa
       61 gcgttcaaca tcgtagacgc tataaggtat taaaaataac agaaatcgtg gcaggtttcc
      121 tcatagctgt cttttgtgct attcctatgc caggtgatcg ctaccgtttg atttcggttg
      181 ccttatccag tctcggcttg ctgtgtgagg ggattatcaa tttgtataat gccaaggaac
      241 actggatttc ttaccaaaag actgcgcaac tcctggagaa agaaaaattc ctctatcaat
      301 gccaaacgga gaaatatgca ggaaagacca aggcttttgc cctatttgtc aagacatgcg
      361 aaggtcttat ctcagaggaa atcaaccagt gggaaagtat ccagtcaaaa gaagtggcag
      421 ctagtgcaga agctccaggg aaaaaagagt aggaggtgga ggaaatgttt caatccagct
      481 acctattgcc cttgctctgg ttaaaaaaag aagccgataa ggaaaagatg agcgcgaccc
      541 agtgccagat atttttcttt tattatcaac tgtttgaact cttatttgct agagaaagcg
      601 acttgaaaga cttgtgtctg ggagggcaag gtttttattt ctcgcagtta gagaaagatt
      661 tgctttctgg agtttcccga tttctaacaa acttggaggg aaaagggact ctcaaggcta
      721 accaagaagt atcagctcgc aaagcccttt ttctagcctt gacaactagc cagtcagatt
      781 ggcaggaatt agctcctgtt tttgattttt atcaggctgt agagagactt gaaacgccct
      841 tactcttgag ttttcaagac agacaagatc tgatgtggat ttaccaatca gctttggaga
      901 aagattatag tgtcaaggtg attggcgaca agcattttgt attgaagaga caagatgcta
      961 ctaaattgac agggcgccaa actcaaactt tggaaattct gagtcaatca gaagacttgg
     1021 tcaatcctgt ctatgttaca ttaggagaaa agggggtgct cttgcttgat taagagagga
     1081 gatgttgtag ctctttattt gccttttcca agtattagta gcgatttggc tgtgaagaat
     1141 catatgtata tctgtattga caacagcatg actaaaaaca aagagttggt taaaaatcag
     1201 accttcaaac cagctctctt gaccagacgt ttggtcaaga actttatgat agaagagccg
     1261 gatctagctc gtaatccttt tacaagacca accttgattg acttagataa ggtatttatg
     1321 ttggataata cggtcattcc gacttcttat ctagccagac ggcgacgcaa tgtctcagaa
     1381 gaattgtacg aggaagtttt ggatcaccta gtccaaccac agctgatttc gctgaacaag
     1441 tctgagttta tgcaactcaa ttcaggaact tattaggagg tagaagatgg caaataaagc
     1501 agtaaatgac tttatactag ctatggatta cgacaaaaag aaactcttga cccatcaggg
     1561 agaaagtatt gaaaatcgtt tcatcaaaga gggtaatcag ctacccgatg agtttgttgt
     1621 tatcgaaaga aagaagcgga gcttgtcgac aaatacaagt gatatttctg taacagctac
     1681 caacgacagt cgcctctatc ctggagcact tctcgtagtg gatgagacct tgttagagaa
     1741 taatcccact cttcttgcgg tcgatcgtgc tccgatgact tatagtattg atttgcctgg
     1801 tttggcaagt agcgatagct ttctccaagt ggaagacccc agcaattcaa gtgttcgcgg
     1861 agcggtaaac gatttgttgg ctaagtggca tcaagattat ggtcaggtca ataatgtccc
     1921 agctagaatg cagtatgaaa aaatcacggc tcacagcatg gaacaactca aggtcaagtt
     1981 tggttctgac tttgaaaaga cagggaattc tcttgatatt gattttaact ctgtccattc
     2041 aggcgaaaag cagat
//
LOCUS       DAVDZK010000089         2053 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVDZK010000089 DAVDZK010000000
VERSION     DAVDZK010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.090"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            180..605
                     /gene="rplK"
                     /locus_tag="VUX16_002145"
     CDS             180..605
                     /gene="rplK"
                     /locus_tag="VUX16_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET8125021.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGIEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            814..1503
                     /gene="rplA"
                     /locus_tag="VUX16_002146"
     CDS             814..1503
                     /gene="rplA"
                     /locus_tag="VUX16_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET8125022.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNEIIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            1775..1933
                     /locus_tag="VUX16_002147"
                     /pseudo
     CDS             1775..1933
                     /locus_tag="VUX16_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT          672 a          384 c          457 g          540 t
ORIGIN      
        1 ctttgagcag cctgcggcta gcttcctagt ttgctctttg attttcattg aatataaaaa
       61 ataaactttt ctcttgcaat tccagataaa tagtgtataa taggtaagta tgtgaaaaac
      121 atacttgtgg gaggtaaaaa tctctaatta ccgccaaaac cacaaaggag gatttaaaaa
      181 tggctaaaaa agtcgaaaaa cttgtaaaat tgcaaatccc tgctggtaaa gctacaccag
      241 ctccaccggt tggacctgct cttggtcaag ctggtatcaa catcatggga ttcacaaaag
      301 agttcaacgc tcgtacagct gaccaagctg gtatgatcat tccagttgtt atctcagttt
      361 atgaagataa atcatttact ttcgttacga aaacaccacc agctgctgtt cttttgaaaa
      421 aagctgcagg tattgaaaaa ggatcaggta cacctaataa aactaaagtt gctacagtta
      481 ctcgtgcaca agtacaagaa attgcagaaa ctaagatgcc agatttgaac gcagcaaacg
      541 tagagtctgc aatgcgtatg atcgaaggta ctgctcgttc tatgggattc actgttgttg
      601 actaatcaat aacacagtag aaaatctcac agcagtctat tagttgcttt tcatactagg
      661 caagtgactg aggcttgtac ttgggtacag caagggagct taaggccgta ggaagagaaa
      721 aaatagtaga ctgaaaaccc gcaagacttc atcatttcga gaagtgacgt gggagatgaa
      781 aatcgattga accacttaca aggagaatag aaaatggcta aaaaaagcaa acaacttcgt
      841 gctgctcttg agaaaatcga cagcacaaaa gcatacagcg tagaagaagc tgtagcactt
      901 gcaaaagaaa ctaactttgc aaaatttgac gcaactgtag aagttgctta caacttgaac
      961 atcgacgtta aaaaagctga ccaacaaatc cgtggagcaa tggtattgcc aaacggtact
     1021 ggtaaaactt cacgcgttct tgttttcgca cgtggtgcaa aagctgaaga agcaaaagct
     1081 gctggtgcag actttgttgg tgaagatgac cttgttgcta aaatcaacga cggttggttg
     1141 gacttcgacg tagttatcgc tacgcctgat atgatggctc ttgttggacg tcttggacgt
     1201 gtccttggac cacgtaactt gatgccaaac cctaaaactg gtactgtaac aatggatgtt
     1261 gctaaagcag ttgaagagtc taaaggtggt aaaatcactt accgtgctga ccgtgcaggt
     1321 aacgttcaag caatcattgg taaagtatca tttgaagctg aaaaattggt tgaaaacttt
     1381 aaagctttca acgaaataat ccaaaaagca aaaccagcta cagctaaagg aacttacgta
     1441 acaaacttga ctatcacaac tactcaaggt gttggtatca aagttgacgt aaactcactt
     1501 taatcagtag ttaaagtaat gtaaaaaagt tgaagacgct atgtctcaac ttttttgatg
     1561 tatgacatgc ccgtcataca tctgaggtgt aagttctcgg tgggcacctg ctaccggtga
     1621 acccaatagc gattcccaag tctgactatc gtgaggtagc ggattaaaac ggtctggaga
     1681 tagaccgttt taagtctgac gctggaaata agaatcgtca gaggaaggga tagcgaaatc
     1741 gtggttctac gaacagggac gtgataataa ggcgtatata gcggataagg tatctggctg
     1801 gggcgaccac tatcaattag tagatcagaa gtcggtgctt aaacgtgcta tatcaaaacc
     1861 agtccttgaa aaatgtggac tggttttctg tttggattat tatcctgaac gacatgcgtt
     1921 aaaagttagt tgaaccgccg tatgccgaac ggcacgtacg gtggtgtaag aggagctaga
     1981 gattatcccc tactcgattt cgaaatttag tggaatgaat ctggaatagt ccatcgagct
     2041 ttctaatact ctt
//
LOCUS       DAVDZK010000090         1938 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVDZK010000090 DAVDZK010000000
VERSION     DAVDZK010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.091"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(30..815)
                     /locus_tag="VUX16_002148"
     CDS             complement(30..815)
                     /locus_tag="VUX16_002148"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET8125023.1"
                     /translation="MKHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVNEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRGSSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            complement(875..997)
                     /locus_tag="VUX16_002149"
     CDS             complement(875..997)
                     /locus_tag="VUX16_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HET8125024.1"
                     /translation="MKIKEQTRKLAADCSKHCFEVVDETDEVSSKYCFEVADGS"
     gene            complement(1165..1593)
                     /locus_tag="VUX16_002150"
                     /pseudo
     CDS             complement(1165..1593)
                     /locus_tag="VUX16_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901186.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
BASE COUNT          576 a          440 c          312 g          610 t
ORIGIN      
        1 aaaaattcaa agaatgatgc aagtattttt tattttcctg taaatttagg tcttcttctc
       61 tccgaatgag ctcgcactcc ttctttgaaa tcctctgttt gagctaagga tttctgtagg
      121 ttcagttcta aagtagcgta accctgccag tctttaaatt ggctctccca aaccaacttc
      181 ttaatggcag cataggaatt acttgaacca cgtcttaatt ttttaagaag ctgttctctc
      241 gtcttttcaa gtttttcagc ttcagaaacg cggtaaacca acccccattc tagggctttt
      301 tctgccgtta aagcctctcc tgtcatagct aattgagcag cacgcgtcac accgatactg
      361 cggcttaaga gatgaattcc ccctgcatct ggagccaaac caacaccaac aaaggcttgg
      421 ataaacttag ccttatccgt cgccaaacag aaatctgccg caacagccat attcgctgcg
      481 gcacctgcaa cagcaccgtc aacttccatt aaaacaggtt tggctatttg cttgatttta
      541 taagaaatcg tattgaccaa ctctgcgatt tttgtcagtg atggaatatc atcctcattc
      601 actgcccgct tcatctctac caaatctccc ccaactgaga agacctttcc attggcattg
      661 attaagataa aatgcacagc tggattttct tctgccaaag tcagagcttc taaaatctcc
      721 tcacacatgg gaatatgaaa accatttgcg acctcaggac ggttcaaggt aaggattgcc
      781 aagtcctctt caagctgata aataatgtgt ttcatcagag ctccttttta ttttataagc
      841 agtttatact cttcgaaaat ttcttcaaac cgcgtcagct tccatctgca acctcaaaac
      901 agtattttga gctgacttcg tcagtttcat ctacaacctc aaagcagtgc tttgagcagt
      961 ctgcggctag cttcctagtt tgctctttga ttttcattga gtgttaaatt atttcacttt
     1021 caaagtatat cttttttagg agcagaaagc aagaaaaaat cgactgaaag tgtctcagcc
     1081 gataagaaag gctcgcttta ggctagaaag catcttattg ctctggcaca taatgagcaa
     1141 cctggcttgt ttttgcaaaa gccattattt caaatcctcc aaaaattgat aaagattggt
     1201 caaacctttg ctcatgacat ccatttcttc cttactcaca ccatcaatga ttttttcaac
     1261 catggccttg tggaagcgtt tatgtagcct atgaaccaag cgacccttct ttgtcaaatg
     1321 tagatgcacc acacgacgat cctgctctga gcgaatgcgt tcaatgtaag ccttgcgttc
     1381 gagattattc aaactagtcg taactgtccc aagaatcacc agcaactctt ttgacacttg
     1441 acttggtgtc acgtctggga atttcccaat cacatcaatc gtatgcattt ctttgatgga
     1501 gatatccttg aaacgactac ctctcaagtt cacttcctca atgacaagga cattgttaaa
     1561 tattcattaa ttcgttggta gtccattttt catatccctc cttcttcaaa aaaactttta
     1621 caatcaaaac atttgacaag agaattatat caaagctcaa acaatgatgc aagtattttt
     1681 tattttcctg taaatttagg ccttcttcgt ttgaaaacgc ttatatatac tcctaaggaa
     1741 agagactcta taatatttgt agtgggtaaa tccactatag atattatgga gcctattttt
     1801 gtgtagaaaa aaagtcccat atgacctata atgaaaagcg acaaaacaac tcattagaaa
     1861 gatttatatg gaacaattac attttatcac aaaattacta gacattaaag accctaatat
     1921 ccagatttta gacatcac
//
LOCUS       DAVDZK010000091         1921 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVDZK010000091 DAVDZK010000000
VERSION     DAVDZK010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1921
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.092"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            112..1845
                     /locus_tag="VUX16_002151"
     CDS             112..1845
                     /locus_tag="VUX16_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010051926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634 family transposase"
                     /protein_id="HET8125025.1"
                     /translation="MRVKQSKSKNTINYAIIKDIKVGNKRTSTIVENLGNHNTLLKEH
                     PDMEPLEWARLRAKELTEKEKEENKDFLITFSQNKQLKQNQLNEYHGGYLFLQDLYHQ
                     LDLPRINKEIQKRHRFNFSLDDILSRLIYGRILAPASKRSTLEFSKTLLEPKEFELQH
                     FYRALEVISNETEFIQEQTYQTSKKMTQRQTEVLYYDCTNFYFEIEAEDEEGLLRQYG
                     PSKEHRPNPIVEMGLFMDKQGIPLAFCIHPGNTNEQTTLKPLERKIVKEYKASKFVVC
                     TDAGLSSKANKMYNSFGERSYVTTQSIKKLKKEYRDWALDKSGWRMVGDKNPIFYNLD
                     ELEHREELKKQLFFKESPFYDEDLPNQRLIVTFSTKYQDYHRTIRERQIERASKLLGK
                     PSQATKKRQTDFKRFLKETSTTKEGEIAEKRILTLDEERIQEEAQYDGLYAVATNLDE
                     DIQTIVVINQRRWEIEESFRIMKQELRARPVYLSRSDRIQAHFTICFLALMIYRLLEK
                     QLGETVTCSELIQTLRNYKFKHLYGAGYLPTYTRTTITDQLHQAFGFQTDFEIISEKN
                     MKKIFKKTKSR"
BASE COUNT          704 a          362 c          341 g          514 t
ORIGIN      
        1 gtgaaaaact cctcataaag gttgatataa ggggattttc ttgtcaaatt tcaccgtttt
       61 ttatttgcgt acttttccgt actttgttat aatagagcga ggtataaaaa gatgagagtg
      121 aaacaatcaa agtcaaaaaa cactatcaac tacgctatta ttaaagacat caaggttgga
      181 aataaacgga cttctactat cgtagaaaac ttaggcaatc ataacacact cttaaaagaa
      241 catcctgata tggaacctct tgagtgggct cgtttacgtg ccaaggaatt aactgagaaa
      301 gaaaaagaag aaaataaaga tttcctcatt acctttagtc agaacaaaca gttaaaacaa
      361 aatcaattga acgaatatca tggaggctat ctcttcctac aagacctcta tcatcaacta
      421 gatttgccta gaattaacaa agaaatccaa aaacgacatc gttttaattt ctctctagat
      481 gatatcctat ctcgattgat ttatggacgg attctagctc ctgcttcaaa acgatccacc
      541 ctagaatttt caaaaacatt actcgaacct aaagaatttg aactccaaca tttttatcgg
      601 gctcttgaag ttatttctaa tgaaacagag tttatacaag aacaaaccta tcaaacttca
      661 aaaaagatga cccaacgaca gacagaagtt ctctactatg actgtactaa cttctatttt
      721 gaaattgaag ctgaagatga ggaaggactt ctgagacaat acggtccatc taaagaacat
      781 cgcccaaatc caattgtgga gatgggactc tttatggaca aacaaggaat tcccctagct
      841 ttctgtatcc accctggaaa tacaaatgaa caaactactc ttaaaccatt agaaagaaag
      901 attgtcaagg agtacaaggc ttcaaaattt gtagtctgta cagatgctgg actctcatca
      961 aaagccaata agatgtacaa ttcttttggg gaacgttcct atgtcacaac tcaatctatc
     1021 aagaagttaa agaaagaata cagagactgg gctttggata aaagtggttg gcgaatggtt
     1081 ggggataaga atcctatctt ttacaatctg gatgagctag agcacagaga ggaattaaaa
     1141 aaacagctct tctttaaaga atctcctttt tatgatgaag atttaccaaa tcaacgcttg
     1201 attgtgacct tttctactaa atatcaagac tatcatcgaa cgatacgaga gagacagatt
     1261 gaacgggcta gtaagttact gggcaagccc agccaagcta ccaagaagag acaaaccgat
     1321 tttaagagat ttctgaaaga aacaagtact accaaagaag gggaaatcgc cgagaaaagg
     1381 attctaactc ttgatgagga acggattcaa gaagaggctc aatatgatgg tctctacgcc
     1441 gtagccacta atctagatga agatatccag acaattgtag tcatcaatca aaggcggtgg
     1501 gaaattgaag agagttttcg tatcatgaag caggaactac gagccagacc cgtttatctc
     1561 agccgttcag ataggattca agcacatttc actatttgtt tcctagcact aatgatttat
     1621 cgtctcttgg aaaaacaact aggagaaaca gtcacctgtt cagaactcat ccaaacctta
     1681 cgcaattaca agttcaaaca tctttatgga gcaggatatc ttccaactta caccagaaca
     1741 actatcacgg atcaactcca ccaagcattt ggtttccaaa ctgattttga gattataagc
     1801 gaaaaaaata tgaaaaaaat ttttaagaaa accaaatcta gataaaaagt acgcattttt
     1861 taaaaagaga aaaagagctc cgaaaagctg tcatatcagt atttaggggc tctttgattt
     1921 c
//
LOCUS       DAVDZK010000092         1764 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVDZK010000092 DAVDZK010000000
VERSION     DAVDZK010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1764
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.093"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(375..1571)
                     /gene="tuf"
                     /locus_tag="VUX16_002152"
     CDS             complement(375..1571)
                     /gene="tuf"
                     /locus_tag="VUX16_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET8125026.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
BASE COUNT          497 a          345 c          354 g          568 t
ORIGIN      
        1 gtataatgct ttttgagttt agtctagtat tatactcttc gaaaatctct tcaaaccgcg
       61 tcagcttcgc cttgtcgtat agatgttact gacttcgtca gttctatcta caacctaaaa
      121 acagtgtttt gagcagtctg cagctaactt tctataacaa aatgaaataa gaacaagaca
      181 aatcaatcaa gacaatcaaa tcgatttcta acaatgtttt agaagtagat gtgtactatt
      241 ctagtttcaa tatattatag tttgctcttt gattttcatt gagtattagt tcaatatcta
      301 aaaaaagaac cttgccaagc aagattcttt tagtgtctga cttaaataat tgttcttctg
      361 ggaactaaat cgaattaagc ttcgatttct gtaaccatac ctgaaccaac agtacgtcca
      421 ccctcacgga tagagaatgt agtaccttgt tctacggcga ttgggtgaat caactcaacg
      481 tcgattgtca cgttatcacc aggcattacc atttcagtac ctgctggaag ttcgattgaa
      541 cctgtaacgt cagtagtacg gaagtagaat tgtggacggt agttgttgaa gaatggagtg
      601 tgacgtccac cttcttcttt agtaaggatg tagacttcac ctttgaattt agtgtgtggg
      661 ttgattgaac ctggtttagc gataacttgt ccacgttcga tttcatcacg ttgaacacca
      721 cgaagaagga cacctacgtt atctccagca agaccttcgt caagttgttt acggaacatt
      781 tcaacaccag taacaactgc tttttgagtt tcttctttga taccaacgat ttcgatttcg
      841 tcgttgactt taacgatacc acggtcgata cgtcctgaag caactgtacc acgtccagtg
      901 attgagaata cgtcctcgac tggaagaagc aatggtttat cagtgtcacg ttctggttct
      961 gggatatact catcaactgt gttcatcaat tccataacga tgtcttcgta tttagagtca
     1021 ccttcaagag ctttaagtgc tgaaccttgg ataactggaa gatcgtcacc tgggaagtcg
     1081 tattctgaca ataggtcacg gatttccatt tcaaccaatt caagcaattc ttcgtcgtca
     1141 accaagtcaa ctttgttcat gaagacgata aggtgtttaa caccaacctg acgtgaaaga
     1201 aggatgtgct cacgagtttg tggcattggt ccgtcagttg aagctactac aaggatagct
     1261 ccgtccattt gagcagcacc agtgatcatg tttttaacgt agtccgcgtg tcctggagcg
     1321 tcgatgtgag cgtagtgacg tttttcagtt tcgtactcaa cgtgcgcagt gttgatagtg
     1381 ataccgcgtt cgcgttcttc tggagcagca tcgatagacg catagtcttt aggttggtta
     1441 actgatgaag gcaagcgacg tgccaaaaca gttgtgatag ctgcagttag ggtagtttta
     1501 ccgtggtcaa cgtgtccgat agtaccaatg ttaacgtgtg gtttactacg atcgtatttt
     1561 tcttttgcca tttgagtaaa agcctccaat aaaatatatt ttatagatag acagtaggca
     1621 atacagtcta actttcctta ctattttatc aaatttcagc taaattgcaa gtgttttaca
     1681 acgtttttgt gaattattct tggtaaaaat ttaactaatt aatagaaagt actaaataga
     1741 cttatccttc aaggagtttt cagc
//
LOCUS       DAVDZK010000093         1654 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVDZK010000093 DAVDZK010000000
VERSION     DAVDZK010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1654
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.094"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(40..357)
                     /locus_tag="VUX16_002153"
     CDS             complement(40..357)
                     /locus_tag="VUX16_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET8125027.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            527..1069
                     /locus_tag="VUX16_002154"
     CDS             527..1069
                     /locus_tag="VUX16_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET8125028.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVGDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            1069..>1654
                     /gene="nth"
                     /locus_tag="VUX16_002155"
     CDS             1069..>1654
                     /gene="nth"
                     /locus_tag="VUX16_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET8125029.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNP"
BASE COUNT          491 a          302 c          365 g          496 t
ORIGIN      
        1 aaggaaattt tgtcaacaga aaactggaaa ttctatgctc taaaatccaa aaacaggtcc
       61 atagagactt agtacgtgtt tgacatgctc gtaatggaat ttatcatagt ttcgccaagc
      121 agtgcgtgct tgatcgttta gttttaggct acccagtcca atcagaagac tggtgggttg
      181 gtaaaatttc tcaagatcaa ttaagatact gttgttcaac ttttccgttt ttttgagctc
      241 ttgcatagta gtgtttagca gctcttgtag tcgaatatca tctgccgtac cctgtttaca
      301 gttttggtag cttttattta acttggatag gagttgaatg agtttcttgt cttccatgtg
      361 agcatcctcc ttgatctgat gtactctttc cctatagtat agcactaaaa aacaaaactg
      421 tcatagtaaa tatgttaaaa ttttgaattt taattacaaa gtttggtgtg ctgatttgta
      481 gccttttcat ggtataatca agagagtaaa tctttatgga ggaagtatga aattaaatat
      541 tcaagaaatt cgtaagcagt ctgaaggttt gaactttgaa caaacgttag atttagttgg
      601 tgacctgcgt gcacgtaatc aagaaatttt agatgtaaaa gatatccttg cagttgggaa
      661 agtacaatat gaagaccgta tgtatttctt agattatcaa ctatcttata ccattgttct
      721 tgcttcgagt cgcagtatgg agccagttga gttagttgaa tcttatccag tcacggaagt
      781 tttcatggaa ggcgcaacta accagctaga tcaagaagtt ttagatgatg acttggtctt
      841 gcccatcgaa aatggggcgc ttgaccttgc tgagagtgta tcagacaata tcctgctaaa
      901 cattcctatc aaggtcttga cggctgaaga agaagctggt caaggatttg tctcaggaaa
      961 tgactggcaa atcatgacag aggaagaata ccaagctcaa caagcagtaa agaaagaaga
     1021 aaacagtcct tttgctggct tacaaggact atttgacgga gatgaataat ggtcttgtca
     1081 aaaaaacgag cacgaaaggt gctagaagaa atcattgccc tcttcccaga tgccaagcct
     1141 agtcttgatt ttaccaatca ttttgaactc ctggttgcgg tcatgttatc agcccagacg
     1201 acagatgcag cggtaaataa ggccacacca ggtctctttg ttgcctttcc aacaccccaa
     1261 gctatgtctg tagcgacaga gagtgagatt gcttcacata tttctcgctt gggattgtat
     1321 cggaataaag ctaaattcct taaaaaatgt gcccaacagt tactagacga ttttgatggt
     1381 caagtccctc agacacgtga agaattggag agtttggcag gtgttggtcg caagacagcc
     1441 aatgttgtca tgagtgtagg atttgggatt ccagcctttg cagtggatac tcatgtggag
     1501 cgtatttgca aacaccacga tattgtcaaa aaatcagcga cgccacttga ggtggaaaag
     1561 cgggtcatgg atatcttgcc gcctgagcag tggttagctg cccatcaggc catgatttat
     1621 tttggaagag ccatttgcca tccaaaaaat ccag
//
LOCUS       DAVDZK010000094         1614 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVDZK010000094 DAVDZK010000000
VERSION     DAVDZK010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.095"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            150..526
                     /locus_tag="VUX16_002156"
                     /pseudo
     CDS             150..526
                     /locus_tag="VUX16_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810398.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            691..990
                     /locus_tag="VUX16_002157"
     CDS             691..990
                     /locus_tag="VUX16_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET8125030.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1251..1591
                     /gene="tnpB"
                     /locus_tag="VUX16_002158"
                     /pseudo
     CDS             1251..1591
                     /gene="tnpB"
                     /locus_tag="VUX16_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT          553 a          315 c          288 g          458 t
ORIGIN      
        1 aagattatac cacattgtgt actatttttg gttcatttta ctataataat aacgatacta
       61 gataatgagg aaaatgcaat ggcaaaccca actttcggag aaaaaaagcg aatacagact
      121 atattgctcg ctatggcgta tatgcagtta tccctaatcc tgaacaaaaa caaattgttc
      181 ttgttcaaca accaaatggt gcttggttcc taccatgtgg agaaattgaa gcaggtgaaa
      241 atcatcagga agccctaaag cgtgagttga ttgaagagct tggtttcaca gcagaaattg
      301 gtacctatta cggacaagtt gacgaatatt tctattctcg tcatcgtgat acctactact
      361 acaatcctgc ctacctctat gaagcaactc ctttcaaaga agtacaaaag ccactagaaa
      421 actttaatca tattgcctgg ttcccgacga ggctatccaa aaccttaaac gtggtagcca
      481 taaatgggcc attgaatctt ggaaaaaaca gcataagatt ggctaatact cttcgaaaat
      541 aaaattcaaa ccacgtcagc gtcgccttac cgtactcaag tataggctgc ggctagcttc
      601 ctagtttgct ctttgatttt cattgagtat aaatcaagcg actttattca aaaagtgcta
      661 taatagaatt agaaaatcgg aggaaatatt atgaagctta tcaatacgac aaactcacac
      721 tcgcaacttg taaaaagtca gctagaaagt accgatgcaa cccttgttga ggtttattct
      781 gcagggaata cagatgttat ttttacccaa gctccgcttc actatgaaat cctcatctca
      841 aacaaacacc gtgctattcg tgagcctgaa atcgaaacca ttcaagaatt tttcttgaaa
      901 cgtaaaattg ataaggcctc tgttgatgaa gccaatatca agacactcta ctcagagaaa
      961 ttaattggaa tttcaatccc aatcaagtaa gaaaattgag taaaaactcg atttgagaga
     1021 aagtccaata agtctttcca taataaaacg catagtagca agagtttcta cacccactat
     1081 tatgcgtttt tatcattttg aaatctactg ctaatcaatg aagaagcaaa gatcaaacta
     1141 ggcagctagt tacaagttac gtaagcgcgt cataacaagg tatctatcct aattccccaa
     1201 cttccagtat actagataaa aaataattat cagaggaaaa gtattgtact atgatgattc
     1261 tactaagtga tttaggtcaa gttcaccttg tttgtggcaa gacagatatg aggcagggaa
     1321 tagactcatt agcctatgta gttaaaaccc actttgaatt ggatcctttc tccggtcaag
     1381 tctttctctt ttgtggtgga cgtaaagacc gctttaaagc cctttactgg gatggtcaag
     1441 gattttggct actatataaa cgctttgaga acggaaaact gacttgacca agtacagaaa
     1501 aggatgtcaa agctctcaca ccagaacaag tagactggct tatgaagggc ttttctatca
     1561 ctccaaaaat aaatccatca gaaagtcgtg atttctattg aaatgaggac tttc
//
LOCUS       DAVDZK010000095         1457 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVDZK010000095 DAVDZK010000000
VERSION     DAVDZK010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.096"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            158..>1457
                     /locus_tag="VUX16_002159"
     CDS             158..>1457
                     /locus_tag="VUX16_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate hydrolase"
                     /protein_id="HET8125031.1"
                     /translation="MNKKKMILTSLASVAVLGAGFVASQPASVRAEGAQPAAEKAPTY
                     DDLLKLLKEFENDAIAAIGKRTDLTDEQKGAKRKEIKEFINKDEILKLVKDEVLTVDD
                     VLTELNAAADGASQIGRSVDKPYVGEYKNNVWAKDNANSGSEAQDLTDDQKQAINEEL
                     DKFAKRDDVQKAREALADLDEKAEKVSKKIELAKKSLETKNESVLKLKALYDEAVKSL
                     GESNELTRRLATEYSNNHDEFQALYESTQEQIEELKDYNEQISEGEETLILAIQNKIS
                     DLDDKIAEAEKKLADSQNGEGVEDYWTSGDEDKLEKLQAEQDELQAELDQLLDEVDGQ
                     EPAPEAPAEQPKPEKSAEQQAEEDYARRSEEEYNRLTQQQPPKAEKPAEEPTQPAPAP
                     EQPTEPTQPEKPVAPKTGWKQENGMWYFYNTDGSMATGWLQ"
BASE COUNT          559 a          248 c          327 g          323 t
ORIGIN      
        1 agggcaaaag tagtatcttt atctattttt gggagtagaa gcttatgata tagaaatttg
       61 taacaaaaat gtaatataaa acacttgaca aatatttacg gggggatata attaatatat
      121 agtctgaaaa ggattatcag aaaagaggta aatttagatg aataagaaaa aaatgatttt
      181 aacaagccta gccagcgttg ctgttttagg ggctggtttt gttgcgtctc agcctgcttc
      241 ggtgagagca gaaggtgctc aacctgcggc agaaaaagct ccaacttacg atgatttact
      301 gaagcttttg aaggagtttg aaaatgatgc aattgcagca attggcaaac gcacagactt
      361 aacagatgaa caaaaaggag caaaacgtaa ggaaatcaaa gaattcatca ataaagatga
      421 aattttgaaa ttggtcaaag acgaggttct tacagtggac gatgtcttga cagaactaaa
      481 cgcagcagct gatggagcta gtcaaattgg acgatcagtt gataaacctt atgttgggga
      541 atataaaaac aatgtttggg ctaaagataa tgctaattca ggttccgaag ctcaagacct
      601 aacagatgac caaaaacaag ccattaatga agagttagat aaatttgcca agcgtgatga
      661 tgtccaaaaa gcaagggaag ctcttgcaga cttggatgag aaagcggaaa aggttagcaa
      721 aaagattgag ctagcaaaaa aatctcttga gactaagaat gagtcagttt tgaagttgaa
      781 agctctttat gatgaagcag ttaaatcact tggtgagtca aatgagctta ctcgacgcct
      841 ggcaacagag tattctaata atcatgatga gttccaggcg ctctatgagt caactcaaga
      901 acaaatcgaa gagttgaaag actacaacga acaaatctct gaaggagaag aaactcttat
      961 ccttgcgatt caaaataaaa tatcagatct ggatgataaa atcgcagaag cggagaaaaa
     1021 gcttgctgac tcacaaaatg gagagggtgt agaagactat tggacttcag gtgatgagga
     1081 caaattagaa aagcttcaag cagagcaaga tgaacttcaa gctgaattgg atcaattgtt
     1141 ggatgaagtt gatggacaag aaccagcccc agaagcacca gctgaacaac caaaaccaga
     1201 gaagtcagca gaacaacaag ctgaagaaga ctatgctcgt agatcagaag aagaatataa
     1261 ccgcttgacc caacagcaac cgccaaaagc tgaaaaacca gctgaagagc caactcaacc
     1321 agcaccagcc ccagagcaac caactgagcc aactcaacca gaaaaaccag tcgctccaaa
     1381 aacaggttgg aaacaagaaa atggtatgtg gtacttctac aatactgatg gttcaatggc
     1441 gacaggatgg ctacaaa
//
LOCUS       DAVDZK010000096         1425 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVDZK010000096 DAVDZK010000000
VERSION     DAVDZK010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1425
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.097"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..1287
                     /locus_tag="VUX16_002160"
     CDS             <1..1287
                     /locus_tag="VUX16_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET8125032.1"
                     /translation="SSGDLIYSINGLGRIRQLFTNQVVLGILDIGFVICILFYFLYID
                     FFVTIIALMLVVINLLLLLLTRKNLEQKSKSFVIAQNDLQNKQIEMIYSMMGIKMEGF
                     EVRTFKQWKGYLDKYLYRYRASELFSSVVNSLFSIITFISPFILLFIMLLPDNHLGNK
                     LGGIFAVYSLSSLLFGKINSIFDTIVAFYNSKTFLSRILEILGEETEINGVVKHDLNG
                     EIALKNVSFSYTRDSKKVLSNVSIEIKKGEKVAIVGSSGSGKSTLSKLLIGLFPASSG
                     SILFDDLDYNLLDKQYLRQQIGIVPQDMTLFNKTIHENIAGDISVSEEEMTKICKLVN
                     IHDEIMEMPMGYNTLVSEMGMNLSGGQRQRIILARALVKKPKIILLDEATSYLDNVNE
                     NEIMQKFKEQNITIIVIAHRLSTIIDSNQIFVMDKV"
BASE COUNT          491 a          176 c          258 g          500 t
ORIGIN      
        1 agtagtggtg atttaattta ttctataaat ggtttgggta gaattcggca attatttaca
       61 aatcaggttg tactaggaat attagatatt ggttttgtaa tttgtatttt gttttacttt
      121 ctatatattg attttttcgt gacgattatc gctcttatgt tagtggtaat aaatttgttg
      181 ttgcttctat tgactagaaa gaatttggaa caaaaaagta aatcttttgt gatagctcag
      241 aatgatctcc aaaataaaca aatcgaaatg atttattcta tgatgggaat aaaaatggaa
      301 ggatttgaag ttcgaacgtt taaacaatgg aaaggttatt tagataagta tctttataga
      361 tatagagcca gtgaattgtt ctcaagtgtt gttaattcgt tattttcaat tatcactttt
      421 atatctccat ttatcctatt atttattatg ttgttgccag ataatcattt aggtaataag
      481 ttaggtggaa tttttgcagt atattcttta tcatctctat tatttggtaa gattaatagt
      541 atttttgata cgattgtagc attctacaat agcaaaacat ttttatctcg gattttagag
      601 attttaggtg aagaaactga aataaatggt gtagtgaaac acgacttaaa tggggaaatc
      661 gcacttaaaa atgtttcatt ttcatatact agagatagta aaaaagtact ctctaatgtg
      721 tctattgaaa taaagaaggg ggaaaaggta gcaattgttg gctcttctgg atcaggtaaa
      781 agtacccttt ccaaattatt gataggttta tttccagcat cctcaggtag tattttattt
      841 gatgacttag attataattt gttggataaa cagtatcttc gtcaacaaat tggcattgtc
      901 ccacaagaca tgactttatt taataaaacc atacatgaga atattgctgg agacatctca
      961 gtctcagagg aagaaatgac aaaaatttgt aagttagtta atatccatga tgaaattatg
     1021 gaaatgccca tggggtataa tactttagtt tcagaaatgg gaatgaatct gtcaggaggg
     1081 caacgtcaga gaattatttt agcaagagcg ctagttaaga aacctaaaat aatactttta
     1141 gatgaagcca caagttatct agataatgtt aatgaaaacg agattatgca gaaatttaaa
     1201 gaacaaaata tcacaattat tgttattgca catcgacttt ctaccattat cgattctaac
     1261 cagatttttg taatggataa agtctagtgg taaaatgtca agcgaccccc cgctcaaagt
     1321 ttgaaaacta tttcaaaaaa agggtgcact aaagaagccc tactgaaaac gatgttttca
     1381 aactgttttc agtagatttt caaggagagg tgcagatata actta
//
LOCUS       DAVDZK010000097         1271 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVDZK010000097 DAVDZK010000000
VERSION     DAVDZK010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1271
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.098"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            1..783
                     /locus_tag="VUX16_002161"
                     /pseudo
     CDS             1..783
                     /locus_tag="VUX16_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397986.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
BASE COUNT          471 a          185 c          236 g          379 t
ORIGIN      
        1 acttggaaaa tactatgtga cgcagtaaag ccgacagatg ggagatataa gactaaagaa
       61 tcactcattc tagtcttgga agataagtta gaaactctaa aaaaacgacg tcctttaact
      121 gaaggagaag tggaaagatt aaatgaagaa tttttagtag aatatacata caattctaat
      181 gctattgaag ggaatacact gactttacgt gaaacagaca tggttcttag aggacttaca
      241 attgaccgaa aatccttaaa agagcatttg gaggtcattg gacataaaga tgcttttgat
      301 tatgtaaggc aacttgttcg ttaaaatgct ccaatatctg aaaagattat aaaagatatt
      361 cactatttgg ttttggcaga taagaaagaa gataggggtg tgtatcgaag agttctagtt
      421 cgaattatgg gagcagccca tgaacctgtg caaccctatt taattgtttc taagatggaa
      481 gagttactgg aacgatacga aaatagcaaa gaagatattg ttactaaact tgcccgtttt
      541 catattgagt tcgaatctat tcatctcttc attgatggaa atggaagaac ggggaggttg
      601 ttgcttaatt tggaactgat gaaagcaggc tatccaccta tcgatataaa atttactgat
      661 agattaaaat attatgaatc ttttgatcac tatcatttta aaggaagatt tgtcagttat
      721 ggcagacatg tttgctctat atttaaatca gaaactagat ctatatttat ctattttaga
      781 taaatgagaa taagagaatg tcaaaatccc ttcaagtctt tgtcaataga tctcttgtaa
      841 gataatctga taatctatag ccccaattat tcacacataa cacaaaaagc atccagaatc
      901 gatatgaaac caaggacgca gagccaaaaa ccaaacgctc ccttctcacg atagcaaaaa
      961 ccagcgtgta ataaaaattt aataattctg acattcaaag ataaatagct tacaattatt
     1021 gataaaatca gctaccatga gtaagtaagt aagtaagtaa gtaagtaagt aagtatctct
     1081 atgaattatg atataatagt tagactgggt tagactgggt tagactgggt tagactgtgc
     1141 tagtgggata gacgatattt ttccgctaga tgtaaacatg aaacgtcctt tcctaaataa
     1201 tataacaaaa gtaataaatt gctaagccta ctagacagtc atcctaattt tttgaataga
     1261 atgtatcgat a
//
LOCUS       DAVDZK010000098         1210 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVDZK010000098 DAVDZK010000000
VERSION     DAVDZK010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1210
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.099"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(190..273)
                     /locus_tag="VUX16_002162"
     tRNA            complement(190..273)
                     /locus_tag="VUX16_002162"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(237..239),aa:Leu,seq:caa)
     gene            complement(283..354)
                     /locus_tag="VUX16_002163"
     tRNA            complement(283..354)
                     /locus_tag="VUX16_002163"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(320..322),aa:Gln,seq:ttg)
     gene            complement(368..440)
                     /locus_tag="VUX16_002164"
     tRNA            complement(368..440)
                     /locus_tag="VUX16_002164"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(405..407),aa:His,seq:gtg)
     gene            complement(455..525)
                     /locus_tag="VUX16_002165"
     tRNA            complement(455..525)
                     /locus_tag="VUX16_002165"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(491..493),aa:Trp,seq:cca)
     gene            complement(530..610)
                     /locus_tag="VUX16_002166"
     tRNA            complement(530..610)
                     /locus_tag="VUX16_002166"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(574..576),aa:Tyr,seq:gta)
     gene            complement(623..695)
                     /locus_tag="VUX16_002167"
     tRNA            complement(623..695)
                     /locus_tag="VUX16_002167"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(660..662),aa:Phe,seq:gaa)
     gene            complement(699..772)
                     /locus_tag="VUX16_002168"
     tRNA            complement(699..772)
                     /locus_tag="VUX16_002168"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(736..738),aa:Met,seq:cat)
     gene            complement(783..872)
                     /locus_tag="VUX16_002169"
     tRNA            complement(783..872)
                     /locus_tag="VUX16_002169"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(834..836),aa:Ser,seq:tga)
     gene            complement(955..1028)
                     /locus_tag="VUX16_002170"
     tRNA            complement(955..1028)
                     /locus_tag="VUX16_002170"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(992..994),aa:Ile,seq:gat)
     gene            complement(1063..1133)
                     /locus_tag="VUX16_002171"
     tRNA            complement(1063..1133)
                     /locus_tag="VUX16_002171"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1099..1101),aa:Gly,seq:tcc)
     gene            complement(1139..1210)
                     /locus_tag="VUX16_002172"
     tRNA            complement(1139..1210)
                     /locus_tag="VUX16_002172"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1176..1178),aa:Val,seq:tac)
BASE COUNT          343 a          315 c          267 g          285 t
ORIGIN      
        1 ctaaaaggac ttagccctgt acaatacaga actaaatcct ttgaataaat taattgtcta
       61 acttttgggg gtcagtacac ttttaatcat gtgcttttat atgaaattag taattattag
      121 taacaattcc aagaaatttc ttatggcata acaaaaagac aaggtttcta acccttgtct
      181 tttctactat accggcggcc ggggtcgaac cggcacgtcc ttgcggacac tggattttga
      241 gtccagcgcg tctgccaatt ccgccacgcc ggcaaatagt aactggggta gctggattcg
      301 aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaataata
      361 taaaataggc gagtgatggg gatcgaaccc acgcatgcca gagccacaat ctggtgtgtt
      421 aaccacttca ccacacccgc cataattcta ttaacacggg cagtaggaat tgaacccaca
      481 ctgaaggttt tggagacctt agttctacct ttaaactatg cccgtaaaat ggaaggggag
      541 ggattcgaac ccccgaaccc gaaggagcgg atttacagtc cgccgcgttt agcctcttcg
      601 ctacccttcc aaaatatata aatggcgcga gacggaatcg aaccgccgac acatggagct
      661 tcaatccatt gctctaccaa ctgagctacc gagccttatt gcgggagcag gatttgaacc
      721 tacgaccttc gggttatgag cccgacgagc taccgagctg ctccatcccg cgttaatata
      781 aaaggaggat gtgggattcg aacccacgca cgcttttaca cgcctgacgg ttttcaagac
      841 cgttcccttc agccggactt gggtaatcct ccaaaatagt ttatacggga acaagcccgt
      901 gtcctcttag tgaatagata atattccaat cccctagtaa tggactaaac actatgggca
      961 cgagtggact cgaaccaccg acctcacgct tatcaggcgt gcgctctaac cacctgagct
     1021 acgcgcccaa gtcaaaaact tggtacaaag aacaaagttc aaagcgggtg acgagaatcg
     1081 aactcgcgac aacagcttgg aaggctgtag ttttaccact aaactacacc cgctaaaatg
     1141 ggagttaacg ggatcgaacc gctgaccctc tgcttgtaag gcagatgctc tcccagctga
     1201 gctaaactcc
//
LOCUS       DAVDZK010000099         1190 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVDZK010000099 DAVDZK010000000
VERSION     DAVDZK010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.100"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..1103
                     /locus_tag="VUX16_002173"
     CDS             <1..1103
                     /locus_tag="VUX16_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET8125033.1"
                     /translation="TLVKPFEQNVTDKDLLDAVNADHKKSAKLKDGTSYPTTDGFHDI
                     DLTVTYEDGSMENVSVKYKVTDTAKADIDTAAAEKKTAIEKTPNLTPEEINVAKRQVD
                     EALAEAKRKVGEATDQAGINRAKQEGLSSIDLVLDQALVQSFGRTNGRRSRRTPPRRS
                     RRSVGFVGNSQTGTTPSAVDKSELRTLVEDLERRLKELEGLSPEAQSILREAQAALAN
                     DSLTAQELAKLLAKVRQALNSIQAGTSADKSPSTSNSNKEAESAKEPTNATDVPLYGV
                     FGAAALSLLGALLFAVARKKNSQLDKLLRELDQLLVELEASDKDKKGLGKAKKLAKKA
                     RTFVDSQQKDPQKEAELISEIKTTLSQLREGV"
BASE COUNT          407 a          227 c          271 g          285 t
ORIGIN      
        1 ctacattagt caaaccattt gaacaaaatg ttacagataa agatttgtta gacgctgtaa
       61 atgctgacca caaaaaatct gctaagttga aagatggaac tagctatcct acaacagatg
      121 gtttccatga tattgatctt acagtgacat atgaggatgg tagtatggaa aatgtatcag
      181 tcaaatacaa agttacagat actgcaaaag ctgacattga taccgcagct gctgagaaga
      241 aaacagcgat tgagaagact ccaaacttaa ccccagaaga gattaacgtt gcgaaacgcc
      301 aggtagacga agctcttgca gaagcgaaac gtaaagtagg agaggcgaca gaccaggcag
      361 gaattaaccg agcgaagcaa gaaggcttat ctagtataga tctggttctg gatcaagctt
      421 tggttcaatc ttttggtaga actaatggta gaagaagtcg cagaactcct ccgcgccgct
      481 ctcgtagaag tgtaggattt gtagggaatt cccaaacagg tacaactcca tcggctgtgg
      541 acaagtctga acttcgtact ctggtagagg atctggaacg ccgcttgaaa gagttagaag
      601 gtctatctcc tgaagcacag agtatcttga gagaggcgca agcggctctt gctaatgact
      661 ccttaacagc tcaagaattg gcgaaactcc ttgctaaagt tagacaggct cttaattcta
      721 tacaagctgg cacatcagct gataagagtc cgtctacgtc aaactcaaat aaggaagcag
      781 aaagcgccaa ggaacctaca aatgcgacag atgtccctct atatggtgtc tttggagctg
      841 cagcactctc tcttctagga gctctcctct ttgcagtggc tcgtaagaaa aactctcaac
      901 tagataagct tttaagagaa ttggatcaac ttctagttga gttagaggct agtgacaagg
      961 ataaaaaagg tttaggcaag gctaaaaaat tagctaagaa agcaagaacc tttgtggata
     1021 gccagcaaaa agatcctcaa aaagaagcag aactaatttc tgaaatcaag actactctca
     1081 gtcaactcag agaaggagtc tagtcttgaa gaaaaaaact actttcaaaa atgcagtgag
     1141 tagttttgta gcgatgatga ggaaataaaa ggctctttgt caactgtagt
//
LOCUS       DAVDZK010000100         1103 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVDZK010000100 DAVDZK010000000
VERSION     DAVDZK010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1103
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.101"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..151
                     /locus_tag="VUX16_002174"
     CDS             <1..151
                     /locus_tag="VUX16_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET8125034.1"
                     /translation="NAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKF
                     VLSRA"
     gene            complement(300..>1103)
                     /locus_tag="VUX16_002175"
     CDS             complement(300..>1103)
                     /locus_tag="VUX16_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET8125035.1"
                     /translation="IDTKATAKKNDIEADDKLTTEEKQAAKDKVDAAAQSGTNPVTPP
                     STTRSRRTPPRRSRRSVGFVGNSQTGTTPSAVDKSELQSLVEDLERRLQDLADLSPEA
                     LEEAQSILREAQVALANDSLTAQELTELLAKVRQALNSIQAGTSADKSPSTSNSNKEA
                     ESAKEPTNATDVPLYGVFGAAVLSLLGALLFAVARKKNSQLDKLSRELDQLLVELEAS
                     DKDKKGLGKAKKLAKKARTFVDSQQKDPQKEAELISEIKTILSQLREGV"
BASE COUNT          279 a          252 c          217 g          355 t
ORIGIN      
        1 taatgccaaa ctggaagcga ccaataatct catcaaactt atcaagcgca atgcctttgg
       61 ttttcgaaac tttgaaaact tcaaaaaacg gatttttatc gctctgaaca tcaaaaaaga
      121 aaggacgaaa tttgtccttt ctcgagctta gctgacttca acccactaca gttgacaaag
      181 agccgaaaaa tctccagact agagaactca ctgatggttc ctaatctgga gattttttat
      241 ttcctcatca tcgctacaaa cctactcact tcgtttttga aagtaagttt tcttcaagac
      301 tagactcctt ctctgagttg actaagaata gtcttgattt cagaaattag ttctgcttct
      361 ttttgaggat ctttttgctg gctatccaca aaggttcttg ctttcttagc taatttttta
      421 gccttgccta aacctttttt atccttgtca ctagcctcta actcaactag aagttgatcc
      481 aattctcttg aaagcttatc tagttgagag tttttcttac gagccactgc aaagaggaga
      541 gctcctagaa gagagagtac tgcagctcca aagacaccat atagagggac atctgtcgca
      601 tttgtaggtt ccttggcgct ttctgcttcc ttatttgagt ttgacgtaga cggactctta
      661 tcagctgatg tgccagcttg tatagaatta agagcctgtc taactttggc aaggagttcc
      721 gttaattctt gagctgttaa ggagtcatta gcaagagcca cttgcgcctc tctcaagata
      781 ctctgtgctt cctcaagtgc ttcaggagat aaatctgcta aatcttgtag gcgacgctcc
      841 aggtcctcta ccagagactg aagctctgac ttgtccacag ccgatggagt tgtacctgtt
      901 tgggaattcc ctacaaatcc tacacttcta cgagagcggc gcggaggagt tctgcgactt
      961 cttgtagtag atggtggagt cacgggattt gttccagact gagctgccgc atctacctta
     1021 tccttagctg cttgcttctc ttcagtcgtc aacttgtcgt ctgcttcgat gtcatttttc
     1081 ttagccgtag ctttcgtatc aat
//
LOCUS       DAVDZK010000101          844 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVDZK010000101 DAVDZK010000000
VERSION     DAVDZK010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..844
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.102"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..469
                     /locus_tag="VUX16_002176"
     CDS             <1..469
                     /locus_tag="VUX16_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET8125036.1"
                     /translation="KNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTELID
                     IICQKFNVSYVDIVGEDKMFNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGISID
                     DESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            469..>844
                     /locus_tag="VUX16_002177"
     CDS             469..>844
                     /locus_tag="VUX16_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET8125037.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLGYNLLIEGTLRTIDVPK"
BASE COUNT          300 a          113 c          175 g          256 t
ORIGIN      
        1 aaagaacata aaatccttac gtaaaacaca tgacttaaca caacccgaat ttgcacgaat
       61 tataggaatt tctcgaaata gcttgagtcg ttatgaaaat ggaactagtt cagtctctac
      121 ggaactaata gatatcattt gtcagaagtt taatgtatct tatgtcgata ttgtaggaga
      181 agataaaatg ttcaatcctg ttgaagatta tgaattgact ttgaaaattg aaattgtgaa
      241 agaaagaggt gctaatctat tatctcgact ctatcgttat caagatagtc agggaattag
      301 cattgatgat gaatctaatc cttggatttt aatgagtgat gatctatctg acttgattca
      361 tacgaatatc tatttagtag aaacttttga tgaaatagag agatatagtg gctatttgga
      421 tggaattgaa cgtatgttag agatatctga aaagcggatg gtagcttaat ggaaatccaa
      481 gattatactg atagtgaatt caaacatgct ttagcaagga atcttcgttc actgacaaga
      541 ggaaaaaagt ccagtaagca acctatagcg attttgcttg gagggcaaag tggtgctggt
      601 aagactacaa ttcatcgtat taaacagaaa gaatttcaag gaaatattgt tatcatagat
      661 ggtgatagtt ttcgttctca gcatccacac tatttagaac tgcagcaaga atatggcaaa
      721 gatagcgttg aatacaccaa agattttgca ggaaaaatgg tagagtcttt agtaacaaaa
      781 ttgagtagtt tgggatacaa tcttttgatc gagggaactt tacgaacgat tgacgttcca
      841 aagg
//
LOCUS       DAVDZK010000102          795 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVDZK010000102 DAVDZK010000000
VERSION     DAVDZK010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..795
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.103"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            1..378
                     /locus_tag="VUX16_002178"
                     /pseudo
     CDS             1..378
                     /locus_tag="VUX16_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263388.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
BASE COUNT          205 a          168 c          177 g          245 t
ORIGIN      
        1 gacttccttc ctcgtgtaca tggttcaggt ctctttactc gtgggcaaac tcaagctctt
       61 tcagtcttga ccttggctcc gatgggagaa actcaaatca ttgatggttt ggatccagag
      121 tacaagaaac gctttatgca ccactataac ttccctcaat attctgtagg ggaaacaggc
      181 cgttacggtg cgccaggtcg tcgtgaaatc ggtcacggtg ctcttggtga gcgtgctctt
      241 gctcaagtct tgccaagctt ggaagaattc ccatacgcta tccgtctagt agcagaagtt
      301 ttggaatcaa acggttcttc atctcaagct tctatctgtg cgggaactct tgcccttatg
      361 gctggtggtg tgccaattac tcttagaaaa tctcttcaaa ccacgtcaac gtcgccttgc
      421 cgtgcgtatg gttactgact tcgtcagttc tattcacaac ctcaaaacag tgttttgagc
      481 aacctgcggc tagtttccta gtttgctctt tggttttcat tgagtataac acattgttag
      541 aagttggttt aaattcccta atcaatttgt tcacatttac cttcgatata ttatatccca
      601 tagttatagt ggaaaacact attgttcgga taaatggtag atgttattcc gactcccttg
      661 ctattgttcc gacaaggtga tataatgtga cagaacggag ggataaaaaa tgtatattac
      721 agcgaaagag gccgctaaaa agtgggggat atctgacaga agggtaagaa ttttgtgctc
      781 agaagggaag attca
//
LOCUS       DAVDZK010000103          768 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVDZK010000103 DAVDZK010000000
VERSION     DAVDZK010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.104"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VUX16_002179"
     tRNA            complement(74..147)
                     /locus_tag="VUX16_002179"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VUX16_002180"
     tRNA            complement(157..242)
                     /locus_tag="VUX16_002180"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VUX16_002181"
     tRNA            complement(250..321)
                     /locus_tag="VUX16_002181"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VUX16_002182"
     tRNA            complement(344..416)
                     /locus_tag="VUX16_002182"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VUX16_002183"
     tRNA            complement(435..516)
                     /locus_tag="VUX16_002183"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VUX16_002184"
     tRNA            complement(522..594)
                     /locus_tag="VUX16_002184"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VUX16_002185"
     tRNA            complement(619..691)
                     /locus_tag="VUX16_002185"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
     gene            complement(694..766)
                     /locus_tag="VUX16_002186"
     tRNA            complement(694..766)
                     /locus_tag="VUX16_002186"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(731..733),aa:Val,seq:tac)
BASE COUNT          196 a          227 c          168 g          177 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ctttgggagt taacgggatc gaaccgctga
      721 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actcccta
//
LOCUS       DAVDZK010000104          763 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVDZK010000104 DAVDZK010000000
VERSION     DAVDZK010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..763
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.105"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            185..>763
                     /locus_tag="VUX16_002187"
     CDS             185..>763
                     /locus_tag="VUX16_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET8125038.1"
                     /translation="MSSSKTSSVSYFYFAFDVLGILIFVGKAYNFINPKGIKMAKQVF
                     QTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAVMSKKMATGDFFPLQVNYEEK
                     MYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFAEGFRNEVQVINTVLSYDENA
                     SAPMAAMFGSSLALSISDIPFDGPIAGVQVGYV"
BASE COUNT          198 a          149 c          174 g          242 t
ORIGIN      
        1 cttggtatct tgatgacttg aattttggtc tcatttctta ggaaaaaaga taagcttcct
       61 agcactcgtc gagtgcgacg tcaccttcct atttttctac agaaatgttc ggcaagccga
      121 accgtccaaa atatcttgtg taattgaaca cggccgaaaa gctgtgtaaa aaagataaac
      181 tgtcttgtct tcatcgaaga cttcgtcagt ttcctatttt tactttgctt ttgacgtcct
      241 tggtatcttg atctttgtag gcaaggcgta taatttcatc aatccaaagg ggattaaaat
      301 ggcaaaacaa gtgtttcaaa cgacttttgc gggtcgtgag ttaattgtag agactggtca
      361 ggttgctaag caagcaaatg gctctgttgt tgtacgttac ggtgagtcaa ctgtcttgac
      421 tgctgccgtt atgtctaaga aaatggcaac tggggatttc ttcccactcc aagtcaacta
      481 cgaagaaaaa atgtatgcgg ctgggaagtt tcctggtggc tttatgaaac gtgaaggacg
      541 tccttcaaca gatgcgacct tgacagcgcg tttgattgac cgtccgattc gtcctatgtt
      601 tgcggaaggt ttccgtaatg aagtccaagt catcaataca gtgctttctt atgatgaaaa
      661 tgcatctgca ccaatggctg ctatgtttgg ttcatctttg gcactgtcta tttcagatat
      721 tccatttgac ggaccaattg ctggggtaca agtgggatat gta
//
LOCUS       DAVDZK010000105          713 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVDZK010000105 DAVDZK010000000
VERSION     DAVDZK010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..713
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.106"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            1..713
                     /locus_tag="VUX16_002188"
                     /pseudo
     CDS             1..713
                     /locus_tag="VUX16_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          279 a          122 c          136 g          176 t
ORIGIN      
        1 tggctagcac aatacaggaa aaacgggtat actattgttg agaaaccaag agggagagta
       61 cctaaaatgg gacgtaatcc aaaaacgaga cctgaagaga ggacagaatt agaacgtctt
      121 caatcagaaa atgagtacct gagagcggag aatgccatcc taaaaaagtt aagagaactc
      181 cgattgaagg aggaaaaaga gaaagaagaa agacagaaat tgttcaagaa ttaatgactg
      241 agttttcgtt agctcttctt ctaaaagcca ttaaactagc tcgttcgacc tactactatc
      301 acttgaaaca gctagataaa ccagataagg accaagagct taaagctgaa attcaatcca
      361 tctttatcga acacaaggga aattatggtt atcgtcgaat ttatttagaa ctaagaaatc
      421 gtggttatct ggtaaatcat aaaagagttc aaggcttgat gaaagtactc aatttacaag
      481 ctaaaatgca acagaaacga aaatattctt ctcataaagg agatgttggc aaaaaggcag
      541 agaatctcat tcaacgtcaa tttgaaggct ctaaaacaat ggaaaagtgc tacacagatg
      601 tgacagaatt tgccattcca gcaagtactc aaaagcttta cttatcacca gttttagatg
      661 gctttaatat cgaaattatc gcctataatc tttcaacttc atccaactta gaa
//
LOCUS       DAVDZK010000106          618 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVDZK010000106 DAVDZK010000000
VERSION     DAVDZK010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.107"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(1..618)
                     /locus_tag="VUX16_002189"
                     /pseudo
     CDS             complement(1..618)
                     /locus_tag="VUX16_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          200 a          115 c          129 g          174 t
ORIGIN      
        1 tcaaaagctt gtttaaaatc tctttattgg ttaaatgtat acgaaaagta ggacgataaa
       61 atcgcttatc actcagttta cggctatcct gttgaatgag tttccagtag cgcttgatag
      121 ccttgtattc atgggatttt cgatgaaact gattcatgat ttgaacacgc acacgactca
      181 tagcacggct aagatgttgt acaatgtgaa agcgatcaag aacaattttt gcattcggga
      241 gtgaaacagt ctgggagact gtttcagcct gagcctagaa atttgaaagc gaagctgttt
      301 agccaagcca tagtaaggac taaacatatc catagtaata attttgacgc gacatcggac
      361 aactctatcg tagcgaagaa agtgatttcg aatgatagct tgtgttcttc cctcaagaac
      421 agtgatgata ttgagattgt taaaatcttg cgcaatgaag ctcatctcca tctcccgatt
      481 gaaacagtca ctccccggac tgtttcaacg tcccaggaca taatctcagg aagacaagaa
      541 aaatcatgtt taaagtgaaa atcattgagc ttacgaataa cagttgaagt tgaaatggcc
      601 agctgatgag caatatcg
//
LOCUS       DAVDZK010000107          600 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVDZK010000107 DAVDZK010000000
VERSION     DAVDZK010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..600
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.108"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            1..600
                     /locus_tag="VUX16_002190"
                     /pseudo
     CDS             1..600
                     /locus_tag="VUX16_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          173 a          117 c          137 g          173 t
ORIGIN      
        1 aggagttcgg actcgactct ctccttcaag aaacacgtgg tggtcgtaac catgcatata
       61 tgacagttga ggaagagaaa gcctttcttg cccgccattt gaaggctaca gaggcaggag
      121 aatttgttac aattgatgcc ttatttcagg cttataaaaa ggagttaggt cgttcctaca
      181 cacgtgatgc cttctatcaa ctgttgaagc gccatggttg gcgaaatatt atgccacgtc
      241 cagaacatct taggaaagca gacgctcaaa ccattgtcgc gtctaaaaat aaaatctcaa
      301 ttcaagaaga cgagaaagcg ctttaaaacc agtagacgtt ttcgtaaggt tcgcttgatg
      361 taccaagatg aggctggttt cggtagaatc agtaaactgg gatcttgttg ggctccaata
      421 ggagtaggtc cacatatcca tagtcactat atacgagaat ttcgctattg ttatggagct
      481 gttgatgccc atacaggcga atcatttttc ttaatagctg gtggatgtaa tactgagtgg
      541 atgaacgcct ttttagaaga gctttcacaa gcttatccag atgattatct tttactcgtt
//
LOCUS       DAVDZK010000108          595 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVDZK010000108 DAVDZK010000000
VERSION     DAVDZK010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..595
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.109"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(12..491)
                     /locus_tag="VUX16_002191"
     CDS             complement(12..491)
                     /locus_tag="VUX16_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET8125039.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          160 a          141 c           80 g          214 t
ORIGIN      
        1 tgcatgactt cctagtgggt acggatagta aactccttaa acacaatgcg taagtctctt
       61 aatactcttt gacgccctcg aaatcgttca ttgcttaaga cgcgttctag ttcttcttgt
      121 ttctctttac tttgtttgtt tctataatct cttagtgttt catgaaagag ataataatca
      181 tctagccaga gacccccctc acttatacga tgactgatct ctcccacttc ttcatagggt
      241 tctttatcgt atctacgctt ctgactttcc tgcttacgga tatagtctaa aattcgattt
      301 cgaaacttgg ttttgaaata tttccttaaa cgtggaatat cgtctaccag tccttcttct
      361 ctactaatca attcatgtaa gcagagcatg ccttcttggt cccaatccga caattcccat
      421 aaatgaaggt aatattcatt tctacactta tacacagtcc cttggacttc ttcatacaat
      481 tctttaatca taattttccc ctttctagat acagtctaac agattagaaa acacatttgt
      541 tacattttct ccattctgtt ccctttagct cctaaactgc acaaaaaaaa gaggc
//
LOCUS       DAVDZK010000109          528 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVDZK010000109 DAVDZK010000000
VERSION     DAVDZK010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.110"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..>528
                     /locus_tag="VUX16_002192"
     CDS             <1..>528
                     /locus_tag="VUX16_002192"
                     /inference="COORDINATES: protein motif:HMM:NF019192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HET8125040.1"
                     /translation="KLKAAKDLLVPKSDNTGLTTAKNALDTERNKAVDTTGKTPASVA
                     AYNDAKQKAQEASDAAQTVLNNPNATEQQIQDEITKVNAAKEKLGKAEAGLTTAATAQ
                     AKQELTTAKEGLEEPVSTDGMTPDSIKAYEAAKKEAAQAVADAKAAAQAAEAKGENAT
                     EAEVNEAKAKVDAAK"
BASE COUNT          241 a           98 c          125 g           64 t
ORIGIN      
        1 aaaaattaaa agcagctaaa gatctgttag taccgaagtc agacaataca ggtttaacaa
       61 cagctaagaa tgcattagat acagagcgta ataaggctgt agatacaaca ggtaagacac
      121 cagcgtcagt agcagcgtac aatgatgcaa aacaaaaagc gcaagaagca tcagacgcag
      181 cgcaaacagt gttaaacaat ccaaacgcaa cagaacaaca aatccaagat gaaattacga
      241 aagtaaatgc agcgaaagag aagttaggaa aagcagaagc aggattaaca acagcagcaa
      301 cagcgcaagc aaaacaagag ttaacaactg caaaagaagg attggaagag ccagtatcaa
      361 cagacggaat gacaccggac agtataaaag catacgaagc agctaagaaa gaagcagcgc
      421 aagcagtagc agatgcaaaa gcagcagcgc aagcagcaga agctaaaggt gaaaacgcga
      481 cagaagcaga agtaaatgaa gcgaaagcga aagtagacgc agctaaag
//
LOCUS       DAVDZK010000110          456 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVDZK010000110 DAVDZK010000000
VERSION     DAVDZK010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.111"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..>456
                     /locus_tag="VUX16_002193"
     CDS             <1..>456
                     /locus_tag="VUX16_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HET8125041.1"
                     /translation="KKVTININGLISKETVQKAVADNVKDSIDVPAAYLEKAKGEGPF
                     TAGVNHVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKGQYFY
                     QVALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVAT"
BASE COUNT          158 a          105 c           93 g          100 t
ORIGIN      
        1 aaaaaagtca ctattaacat aaacggttta atttctaaag aaacagttca aaaagccgtt
       61 gcagacaacg ttaaagacag tatcgatgtt ccagcagcct atcttgaaaa agccaagggt
      121 gaaggtccat tcacagctgg tgtcaaccat gtgattccat acgaactctt cgcaggtgat
      181 ggcatgttga ctcgtctctt actcaaggca tctgacaagg caccatggtc agataacggt
      241 gacgctaaaa atccagccct atctccacta ggcgaaaacg tgaagaccaa aggtcaatac
      301 ttctatcaag tagccttaga cggaaatgta gctggcaaag aaaaacaagc gctcattgac
      361 cagttccgag caaacggtac tcaaacttac agcgctacag tcaatgtcta tggtaacaaa
      421 gacggtaaac cagacttgga caacatcgta gcaact
//
LOCUS       DAVDZK010000111          416 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVDZK010000111 DAVDZK010000000
VERSION     DAVDZK010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.112"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            complement(1..416)
                     /locus_tag="VUX16_002194"
                     /pseudo
     CDS             complement(1..416)
                     /locus_tag="VUX16_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          129 a           72 c           92 g          123 t
ORIGIN      
        1 tgaatagctc aaaagcttgt ctaaaatctc tttattggtt aaatgcatac gaaaagtagg
       61 gcgataaaaa tgtttatcgc tgagtttacg actatcctgt tgtatgagct tccagtagcg
      121 cttgatagcc ttgtattcat gagactttcg atccaattga ttcatgattt gaacacgcac
      181 acgactcata gcacggctaa gatgttgtac aatgtgaaag cgatcaagaa cgattttagc
      241 attcgggagt gaaacagttt gggagactgt ttcagcctga gcctagaaat ttgaaagcga
      301 agctgtttag ccaagtcata gtaaggacta aacatatcca tagtaataat tttgacgcga
      361 catcggacag ctctatcgta gcgaagaaag tgatttcgaa tgatagcttg tgttct
//
LOCUS       DAVDZK010000112          340 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVDZK010000112 DAVDZK010000000
VERSION     DAVDZK010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.113"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..290
                     /locus_tag="VUX16_002195"
     CDS             <1..290
                     /locus_tag="VUX16_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET8125042.1"
                     /translation="HLYDLRMTILLNLSTLYLYNQDKNMCKQICYTLLEDAKNKKSYD
                     RLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQAKER"
BASE COUNT          116 a           67 c           59 g           98 t
ORIGIN      
        1 aacatttata tgacttgcga atgacaattc tattaaacct ttccacactc tatctataca
       61 atcaagataa aaacatgtgt aagcaaatct gctacacttt actagaggac gccaagaata
      121 agaaaagcta cgataggctg gctatctgct atgtccgtat tgggatttgt acagacgatt
      181 ctaaacttat ccaaaaaggg ttctcccttc tggagctaac cgaggaaact tctatgctgt
      241 ctcatctcaa aaaagaagta gagatctatt accaagcgaa ggaaagataa aaaagccgag
      301 ggatttcctc gactctttac atattatttg ttcgttagtt
//
LOCUS       DAVDZK010000113          334 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVDZK010000113 DAVDZK010000000
VERSION     DAVDZK010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.114"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..>334
                     /locus_tag="VUX16_002196"
     CDS             <1..>334
                     /locus_tag="VUX16_002196"
                     /inference="COORDINATES: protein motif:HMM:NF019202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET8125043.1"
                     /translation="SAKDAVTAATTNDGVTQAQNDGTTAVNNVDTTPKAKPSAKAEID
                     AKVQDANNAIDQNQDLTDDERREAKKAVKDAADEAKANIDKATSAGELTTAKNNGLDK
                     LNEPQDASV"
BASE COUNT          119 a           70 c           85 g           60 t
ORIGIN      
        1 aaagtgctaa agatgcggtt actgccgcaa ctaccaacga tggtgtgact caagctcaga
       61 atgatggaac tactgctgtt aacaatgttg atacaacgcc aaaagcgaaa ccatcagcca
      121 aggcagaaat tgatgccaag gttcaagatg ccaacaatgc cattgaccag aatcaagatc
      181 tgacggacga tgagcgtaga gaggctaaga aagcagtgaa ggacgcagct gatgaagcta
      241 aggctaatat tgacaaggcg acatctgcag gagagctcac aactgctaag aacaacggtc
      301 ttgataagtt gaatgagcca caagacgcaa gcgt
//
LOCUS       DAVDZK010000114          277 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVDZK010000114 DAVDZK010000000
VERSION     DAVDZK010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.denovo.115"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            <1..>277
                     /locus_tag="VUX16_002197"
     CDS             <1..>277
                     /locus_tag="VUX16_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET8125044.1"
                     /translation="VDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVTAVY
                     EEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDE"
BASE COUNT           93 a           51 c           74 g           59 t
ORIGIN      
        1 acgtggatgc tgaattgcaa gctgaaatca ttgcagccta caacagtgac ctccaaaagg
       61 cagttcaagt agaagagaaa ttggcccgtg aagctgcgac tcaagtagtg aaagaccaag
      121 tgactgccgt ttacgaagaa aaatatgcgg accacgaaga atttgaccgt attatgcgtg
      181 atgtggctga aatcttggaa caaatggaac acgcagaagt gcgacgttta attacagaag
      241 acaaggtgcg tcctgatggt cgtaaggtcg atgaaat
//
LOCUS       DAVDZK010000115        41210 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 133b
            SAMEA2446248-rid19717313.guided.017, whole genome shotgun sequence.
ACCESSION   DAVDZK010000115 DAVDZK010000000
VERSION     DAVDZK010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2446248
            Sequence Read Archive: ERR540588
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001929578.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001929578.1
            Genome Coverage       :: 185x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 03:38:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,242
            CDSs (total)                      :: 2,194
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 77 of 176
            Pseudo Genes (incomplete)         :: 78 of 176
            Pseudo Genes (internal stop)      :: 53 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41210
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2446248-rid19717313.guided.017"
                     /strain="133b"
                     /db_xref="taxon:1313"
     gene            111..1370
                     /locus_tag="VUX16_002198"
     CDS             111..1370
                     /locus_tag="VUX16_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET8125045.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1446..1581
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1620..2120
                     /locus_tag="VUX16_002199"
     CDS             1620..2120
                     /locus_tag="VUX16_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET8125046.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARSLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2196..2564
                     /gene="rplL"
                     /locus_tag="VUX16_002200"
     CDS             2196..2564
                     /gene="rplL"
                     /locus_tag="VUX16_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET8125047.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DATDAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2766..2939
                     /locus_tag="VUX16_002201"
     CDS             2766..2939
                     /locus_tag="VUX16_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8125048.1"
                     /translation="MTKELQSSRHIVISFLVREMGIDIVEAISLMAELEKSGLVRLES
                     SGDLILKELGGAL"
     gene            2936..3715
                     /locus_tag="VUX16_002202"
     CDS             2936..3715
                     /locus_tag="VUX16_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET8125049.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKTLKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVGNSNRPSVKKRLGQDENDTAPVSHLAPSETEVSETKYSE
                     TDSLFIEDEEERNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            3814..5172
                     /gene="dcm"
                     /locus_tag="VUX16_002203"
     CDS             3814..5172
                     /gene="dcm"
                     /locus_tag="VUX16_002203"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET8125050.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARESYKSIFQT
                     EGEIEFHDIRDVSDDEFKKLRGKVDVICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQVLNSKDFGVPQNRE
                     RVFIIGHSRKKGTRLLFPFRREGQATNSETLKALGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLEKRQNGRRFKDNQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYQVAGILIDGQFYRLRIRR
                     ITPKECFRLQGFPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDES
                     IK"
     gene            5156..5605
                     /locus_tag="VUX16_002204"
     CDS             5156..5605
                     /locus_tag="VUX16_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8125051.1"
                     /translation="MKALNRESILDCDELETELHDAEIKQLDEQIFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFVDDNQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKQPINFANLLDSLIVSEYQMEPNLWEVSHD"
     gene            5598..5978
                     /locus_tag="VUX16_002205"
     CDS             5598..5978
                     /locus_tag="VUX16_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8125052.1"
                     /translation="MIDLYLSKNNHRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            5991..6224
                     /locus_tag="VUX16_002206"
     CDS             5991..6224
                     /locus_tag="VUX16_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET8125053.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            6227..6814
                     /locus_tag="VUX16_002207"
     CDS             6227..6814
                     /locus_tag="VUX16_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET8125054.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILQILYGASLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGIGFISLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGLVRYKSDLWGSMGLHLVWNLSVYVLFLL"
     gene            7191..7505
                     /locus_tag="VUX16_002208"
     CDS             7191..7505
                     /locus_tag="VUX16_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET8125055.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            7521..7907
                     /locus_tag="VUX16_002209"
     CDS             7521..7907
                     /locus_tag="VUX16_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET8125056.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            7936..9318
                     /locus_tag="VUX16_002210"
     CDS             7936..9318
                     /locus_tag="VUX16_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET8125057.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLHL
                     EKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEYD
                     KLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRKE
                     DLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTKE
                     NTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYGM
                     MFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQA
                     TCEAEVAGVD"
     gene            9321..9473
                     /locus_tag="VUX16_002211"
     CDS             9321..9473
                     /locus_tag="VUX16_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET8125058.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            9496..10701
                     /locus_tag="VUX16_002212"
     CDS             9496..10701
                     /locus_tag="VUX16_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HET8125059.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            10744..10965
                     /locus_tag="VUX16_002213"
     CDS             10744..10965
                     /locus_tag="VUX16_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8125060.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            11082..11579
                     /locus_tag="VUX16_002214"
     CDS             11082..11579
                     /locus_tag="VUX16_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HET8125061.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            11554..12060
                     /locus_tag="VUX16_002215"
     CDS             11554..12060
                     /locus_tag="VUX16_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET8125062.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            12044..14491
                     /locus_tag="VUX16_002216"
     CDS             12044..14491
                     /locus_tag="VUX16_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET8125063.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            14494..16671
                     /locus_tag="VUX16_002217"
     CDS             14494..16671
                     /locus_tag="VUX16_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET8125064.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            16668..17669
                     /locus_tag="VUX16_002218"
     CDS             16668..17669
                     /locus_tag="VUX16_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET8125065.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            17666..18601
                     /locus_tag="VUX16_002219"
     CDS             17666..18601
                     /locus_tag="VUX16_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET8125066.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            18845..18961
                     /locus_tag="VUX16_002220"
     CDS             18845..18961
                     /locus_tag="VUX16_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET8125067.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            18977..20896
                     /gene="tet(M)"
                     /locus_tag="VUX16_002221"
     CDS             18977..20896
                     /gene="tet(M)"
                     /locus_tag="VUX16_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET8125068.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            21015..21182
                     /locus_tag="VUX16_002222"
     CDS             21015..21182
                     /locus_tag="VUX16_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET8125069.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(21242..21379)
                     /locus_tag="VUX16_002223"
                     /pseudo
     CDS             complement(21242..21379)
                     /locus_tag="VUX16_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            21795..21878
                     /locus_tag="VUX16_002224"
     CDS             21795..21878
                     /locus_tag="VUX16_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HET8125070.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            22003..22740
                     /gene="erm(B)"
                     /locus_tag="VUX16_002225"
     CDS             22003..22740
                     /gene="erm(B)"
                     /locus_tag="VUX16_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HET8125071.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            23095..23649
                     /locus_tag="VUX16_002226"
     CDS             23095..23649
                     /locus_tag="VUX16_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002402802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET8125072.1"
                     /translation="MIFGYARVSTDDQNLSLQIDALTHYGIDKLFQEKVTGAKKDRPQ
                     LEEMINLLREGDSVVIYKLDRISRSTKHLIELSELFEELSVNFISIQDNVDTSTSMGR
                     FFFRVMASLAELERDIIIERTNSGLKAARVRGKKGGRPSKGKLSIDLALKMYDSKEYS
                     IRQILDASKLSKTTFYRYLNKRNA"
     gene            23653..26571
                     /locus_tag="VUX16_002227"
     CDS             23653..26571
                     /locus_tag="VUX16_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HET8125073.1"
                     /translation="MAMKRILTTSQREQLLSVDHLSEEDFKAYFSFSDYDLEVINQHR
                     GKVNKLGFAIQLCLARYPGCSLSNWPIKSTRLTSYVSRQLHLDAIDLNSYDHRNTRAN
                     HFNEILEVFNYHRFGSANTQKQLIEYLIELALENDDSIYLMKKTIDFLTRKRIIFPSI
                     ATLEDIISRCRDKAENNLFSILLCSLTDIQIEKLESLFQIYEETKITKLAWLKDIPGK
                     ANPESFMSICKKVEVIASMGLGTINVSHINRNRFLQLARLGENYDAYDFSRFELEKRY
                     SLLIAFLVNHHQYLIDQLIEINDRILASIKRKGTRDSQEQLKEKGKLATKKLEHYASL
                     IDALHFAKDNDSNPFDEIERIMPWEDLVQDGEEAKKITGNKNHGYLEMVRNKANYLRR
                     YTPMLLRTLSFKATPAANPVLMALTQLTDLHNSGKRKIPADTSTDFVSKKWKSLVRPE
                     EGKIDRSYYELVAFTELKNNIRSGDISVEGSMIHRNIDDYLVDLSACIDSETIPDTFE
                     DYLKDREIILDLQLQFYSTVDKRISRANLKKLEKVTPSEAEIYRKKLYSIIPKIRLSD
                     LLIEVDSWTNFSQEFSHDSTGKPPSEQERKIIFAALLGLGMNIGLEKMAQSTPGISYS
                     QLANAKQWRFYKEALTRAQSVLVNYQLKLPVADFWGEGKTTASDGMRVPVGVSALKSD
                     VNPHYKSMEKGATMIRSINDRHTTHHIEVASTNTREATHTLDGLLYHETDLDIEEHFT
                     DTNGYSDQVFGMTALLGFDFEPRIRNIKKSQLFSIKSPSYYPNLSEDISGKINVKIIE
                     ENYDEIKRIAYSIQTGKVSSSLLLGKLGSYARKNRVALALRELGRIEKSIFMIDYITD
                     SELRRRITHGLNKTEAINALARELFFGRRGKFMERDIRRQLQSASALNVLINAISIWN
                     AVYLQAAYNYLVKIDPEVTKYMKHVSPINWEHITFLGEYKFDLLSIPKHLRELNIKNK
                     "
     gene            complement(26645..26866)
                     /locus_tag="VUX16_002228"
                     /pseudo
     CDS             complement(26645..26866)
                     /locus_tag="VUX16_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            27371..27793
                     /locus_tag="VUX16_002229"
     CDS             27371..27793
                     /locus_tag="VUX16_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET8125074.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            27790..28020
                     /locus_tag="VUX16_002230"
     CDS             27790..28020
                     /locus_tag="VUX16_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET8125075.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            28481..28684
                     /locus_tag="VUX16_002231"
     CDS             28481..28684
                     /locus_tag="VUX16_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET8125076.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            28766..29983
                     /locus_tag="VUX16_002232"
     CDS             28766..29983
                     /locus_tag="VUX16_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET8125077.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            30253..30843
                     /locus_tag="VUX16_002233"
     CDS             30253..30843
                     /locus_tag="VUX16_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET8125078.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVAEGKIDA
                     EEKGLYRLPDIYLDEWFVLQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEVERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNKIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            30843..31679
                     /locus_tag="VUX16_002234"
     CDS             30843..31679
                     /locus_tag="VUX16_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HET8125079.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIHIFEEILCSNTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AEKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISFDNSVQVIREIMQQ
                     IF"
     gene            31962..32261
                     /locus_tag="VUX16_002235"
     CDS             31962..32261
                     /locus_tag="VUX16_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8125080.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIVDGKAVEVTLREPYSRDLLQVVKSIKQRQKLIAYRYKEGKLLFVKKEASDVL"
     gene            32251..32739
                     /locus_tag="VUX16_002236"
     CDS             32251..32739
                     /locus_tag="VUX16_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8125081.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYSIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     TKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            32739..34616
                     /locus_tag="VUX16_002237"
     CDS             32739..34616
                     /locus_tag="VUX16_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET8125082.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGQEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQETDERWWNYQINPLNQRQENHLEGLRIRDLTFESSL
                     K"
     gene            34637..34879
                     /locus_tag="VUX16_002238"
     CDS             34637..34879
                     /locus_tag="VUX16_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET8125083.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            34896..35750
                     /locus_tag="VUX16_002239"
     CDS             34896..35750
                     /locus_tag="VUX16_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET8125084.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTISGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            35804..36163
                     /locus_tag="VUX16_002240"
     CDS             35804..36163
                     /locus_tag="VUX16_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET8125085.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            36156..38471
                     /locus_tag="VUX16_002241"
                     /pseudo
     CDS             36156..38471
                     /locus_tag="VUX16_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241830.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            38483..41188
                     /locus_tag="VUX16_002242"
     CDS             38483..41188
                     /locus_tag="VUX16_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET8125086.1"
                     /translation="MKDKREIIRARKAFRRSLKDEKKFLKQGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSFLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKESRKERKTNQKFLYGQESKQKSNFFFQGKSLEELKAKKE
                     VKAAKENLKSTKQAYKYKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     FRKLKKQGLSSVQNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELQKPV
                     HLFSSETYKDYLSTLWHDLNDGDDLKSMQDLYETPKYKLSKDDQEEIKELKEEGVYAS
                     MQELDNPFEGQSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQTIVAPMDAVVSL
                     DGDNIILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDIIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYDFLKSQGVSPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATDSSWDDESWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTSDGSTRYTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPADYGHVAFVGARRF"
BASE COUNT        13695 a         7032 c         8447 g        12036 t
ORIGIN      
        1 gttttgaggt tgcagataga actgacgaag tcagtaacca cacctacggc aaagtgaatc
       61 tgaagtggtt tgaagagagt acaacttgtc ttttagaaaa ggagcctaca atgaaagtct
      121 ttcagcatgt aaatatcgtg acttgtgatc aagatttcca tgtttatctt gatggaatct
      181 tagcagtcaa ggattctcaa atcgtctatg tcggtcaaga taagccagcg tttttagagc
      241 aagctgagca gattatagac tatcagggag cttggattat gcctggtttg gtcaattgtc
      301 acacccattc tgcaatgaca ggtctgagag ggatccgaga tgacagcaat ctccatgaat
      361 ggctcaatga ctatatctgg ccagcagaat ctgagtttac tcccgacatg actaccaatg
      421 cggtcaaaga agccctgaca gagatgctcc agtcaggaac aacaaccttt aacgatatgt
      481 ataatcccaa tggtgtggat attcagcaaa tttatcaggt ggtgaaaact tccaagatgc
      541 gttgttattt ttctccgact ctcttttctt cagagacaga aacaactgct gagactataa
      601 gcagaactcg atccatcata gacgaaatct taaaatataa aaatccaaat ttcaaggtta
      661 tggtagcacc tcattctccg tatagctgca gtagagactt gctggaagcg agtttggaaa
      721 tggcaaaaga gctaaatatt ccgctccatg tccatgtggc ggagaccaag gaggagtcag
      781 gaattatcct caaacgatac ggcaaacgcc cccttgcttt tcttgaagaa ctgggttatt
      841 tagatcatcc gtccgtattt gctcacgggg tcgaattaaa cgagagagaa attgaacgct
      901 tggcatcttc tcaagtggct atcgcccaca atcctatcag taacctcaaa ctggcatcag
      961 gaattgctcc aattatccag ctccaaaaag cgggagtagc agtcggaatt gcgactgact
     1021 cggttgcttc caataacaat ctagatatgt ttgaggaagg aaggactgca gctcttcttc
     1081 agaagatgaa aagtggggat gccagccagt ttccaatcga aacagctctc aaggtactga
     1141 caatcgaagg ggctaaggcc cttggaatgg aaaatcagat aggaagtctg gaagtcggca
     1201 agcaagcaga ttttctggtc attcaaccac aagggaaaat tcatctccaa cctcaggaaa
     1261 atatgctgtc tcacctggtt tatgcagtta aatctagtga tgtagatgat gtttatatcg
     1321 ccggagaaca ggttgttaag caaggtcaag tcctgacagt agaactttaa aagaaaaatc
     1381 acgaaaaatt ttaaaaaaag tttgcaaaaa tcttgcattc tttttttgac tatgctatac
     1441 ttatatacgg tttaaaaaaa ctgcctaaga cagtagggga gctcgactca taaatatcct
     1501 accgaggaca agacgtatca tgtaaaaaga agcgtattgt actttcgtgt ctaggtttgg
     1561 gcgcgttttt ctttttgaaa aattccccaa gcaaaataat tacggaggtg aacacactaa
     1621 tgagtgaagc aattattgct aaaaaagcgg aactagttga cgtagtagct gaaaaaatga
     1681 aagctgctgc atctatcgtc gttgtagacg ctcgtagttt gacagttgag caagatacag
     1741 ttcttcgtcg tgagcttcgt ggaagcgaag ttgagtataa agttattaaa aactcaatct
     1801 tgcgtcgtgc agctgaaaaa gctggtcttg aagatcttgc atctgtattt gttggaccat
     1861 ctgcagtagc attttctaat gaagatgtta tcgcaccagc gaaaatcttg aacgactttt
     1921 ctaaaaacgc tgaagcactt gaaattaaag gtggtgcaat cgaaggcgct gtcgcatcta
     1981 aagaagagat tcttgcactt gcaactcttc caaaccgcga aggacttctt tctatgctcc
     2041 tttctgtact tcaagcgcca gtgcgcaacg ttgctcttgc agtcaaagcg gttgcagaaa
     2101 gcaaagaaga cgcggcttaa tcttaagcta catagcgtag cctagctacg aaaaaaacta
     2161 ttataaaatt taaaacttat ttggaggaaa taacaatggc attgaacatt gaaaacatta
     2221 ttgctgaaat taaagaagct tcaatccttg aattgaacga ccttgtaaaa gctatcgaag
     2281 aagaatttgg tgtaactgca gctgctcctg tagctgttgc tgcagctgat gcaactgatg
     2341 ctggtgctgc taaagattca ttcgacgttg aattgacatc tgcaggcgac aaaaaagttg
     2401 gtgttatcaa agttgtacgt gaaatcactg gtcttggtct taaagaagct aaagaacttg
     2461 ttgacggtgc accagcactt gttaaagaag gcgttgcaac tgcagaagct gaagaaatca
     2521 aagctaaatt ggaagaagct ggagcttcag ttactcttaa ataagaggca tataccaatt
     2581 agaaatcgga atactatagt atcagccttt tagaatcgtg aacacatttt agaaactgat
     2641 aaattaattt agtttcctac caaaaaccct accaaaaatt aatttggcag ggtttttctt
     2701 tttaacaaat ttatcgtgga gaacaattga atattgttct ccttttttta ttttcaggag
     2761 gaaaaatgac aaaagaatta caatcatcac gccatattgt catttcattt ttagtacgtg
     2821 aaatgggaat tgacattgtt gaggccatct ctcttatggc tgaattagaa aaaagtggct
     2881 tggttcgctt ggaatcaagt ggagatttaa tactcaaaga acttggagga gcgctatgaa
     2941 acgaattacc gcaaatcaat accaaacttc agaacggtat tataaattac ctaaaattct
     3001 ttttgaagat gagaaatata tggatatgaa actagaagta aaggtggctt attctatttt
     3061 aaaagatcgt ttagaattat ctctcagtcg tggttggata gatgaagaag gagcggttta
     3121 tttagtattt tctaattcta aactgatgaa gctattaggt tgttcgaagt caaaattact
     3181 gtccatcaaa aaaactctta aagaatatga cttaattgat gaagttcaac agtcttcaag
     3241 tgagaagggg agactagcta ataagattta tttaggggaa ttatcttcta ccccagtagg
     3301 taattcaaac aggcctagtg ttaaaaaaag actagggcag gatgaaaatg atacggcccc
     3361 cgtctcacat ttagccccta gtgagactga agttagtgag actaaatata gtgagactga
     3421 ttctttattt attgaggatg aggaggagag gaatactcaa cctatcttga aaagaaaagt
     3481 agaaaaggtc acaaaatatg atcgagatta tatttgggga ttggtacaag atcaatttag
     3541 acgagagggg ttttctgaaa cagccagtga aattgctatg actgattttg agagaatcta
     3601 tcagtatgct cttgacaatg ttcgctttgt tagacgtgcg gaagtacttg ctgaatttgt
     3661 gtttaatggc ttgtattctg tttggaacaa ccgtgttaga aaaggaggtg gttaaatgtc
     3721 gccaatcgag tggatattag ttatgctcat tgtcatttca agtggagtga cagttctgac
     3781 aatgatagtc gataagaaag gggtgataaa gaattgagat ttattgattt attttcaggt
     3841 atcggtggct ttcgacttgg aatggaaagt gttggacacg agtgtattgg attttgtgag
     3901 atcgataaat ttgctagaga atcttataag tccatttttc aaacggaagg agaaatagaa
     3961 tttcatgaca tacgagatgt ttcagatgac gaatttaaaa aacttagagg gaaagtcgat
     4021 gtcatctgtg ggggattccc ttgtcaagca ttttcaatcg caggaagacg attgggattt
     4081 gaagatacta gaggaacttt gttctttgaa attgctcggg cggccaaaca aatccaacca
     4141 cgttttcttt ttcttgaaaa tgttaaaggc ctactcaatc acgataaggg acggacgttc
     4201 accacaatcc ttaccacact tgatgagttg gggtttgatg ttgagtggca ggtgcttaac
     4261 agtaaggatt ttggcgttcc ccaaaacaga gagagggtgt ttattatcgg acattctaga
     4321 aagaaaggta cccgactcct atttcctttc agacgagaag gtcaagcaac taactctgag
     4381 actttgaaag cactaggaaa tttgaatcca tcaaaaagtg gaatgagtgg taaagtctat
     4441 tattcagaag gtcttgcgcc aaccttagtt cgtggaaaag gagaaggatt taaagttgcg
     4501 attccttgta tgacaccaga cagattagaa aagagacaaa atggtagacg tttcaaggat
     4561 aatcaagagc caatgtttac tttaaatact caggatcgcc atggtattgt cgttgttgga
     4621 gatttaccaa ctagctttaa ggaaactggt cgcgtctatg gaagtgaggg gctatctcca
     4681 acactgacta cgatgcaagg tggagataaa atccccaaaa tactgattcc agaaccaatc
     4741 caatttctaa aagtccgaga ggcaacgaaa aaaggatatg ctcaagcaga gattggggat
     4801 tcaatcaatt tagaaagacc aagttctcag tatcgtcgtg gtagagttgg aaaaggtata
     4861 gcgaatacgt taacaactag tgggcaaatg ggagtagtag tggctagcta tgaaggagaa
     4921 gataaacaag tttaccaagt agctggtatc ttaattgatg ggcaatttta ccgtttgagg
     4981 atacgacgaa tcactcctaa agagtgtttt agactgcagg gctttcctga ttgggctttt
     5041 gaagctgcta gaaaagtctc tagtaatagt cagctctata aacaagctgg taatagtgta
     5101 accgttcctg tgattgccgc aatcgcaaaa aaattaaaag aaatagagga aaaagatgaa
     5161 agcattaaat agagaatcaa tactagattg tgatgaatta gaaacagaat tacatgacgc
     5221 agaaatcaaa cagctggatg aacaaatatt tttaatgcct aattatccat gtgagtttga
     5281 ggtgacattt ttagatgatt accataaaaa acataattac ccactatttt atgaatccta
     5341 tcttcaaaac attatggaat tccttgaaag tcaggatata aagaacggag ctgatgcctt
     5401 tgtagatgat aatcagaatc tagtttttgt tttatatgga caaggctatc gagccgaggg
     5461 aaaagaggga atacttacaa cccaagtaac tgtaaaagct tatgatgaag acaagcaacc
     5521 gattaacttc gcaaatttat tagattcctt aatcgtatca gaatatcaaa tggaaccgaa
     5581 tctttgggag gtttcccatg attgatctct atctaagtaa aaataaccat agaaatcaac
     5641 ttcttttgga tttcttccaa aactatggta tcgaggtatc ttgtcattca gtttctgaaa
     5701 tgacaaagga caaattaatt gagatgatga gctattcttc agattgtttc gagtttttat
     5761 ctcccaattt attacgattt aagaaccgtg acaatttaag attaacggat tttattgaaa
     5821 tgatcttaaa aaatcctgaa ctaaccatca gacttcctct tgcggtttcg aataaaagag
     5881 tttatccaaa tctgaatctg gaggaggcta gagctttatt gccaagagat acgaaacaat
     5941 tgatttacat ggcacaaaca cattatttat ctaactaaag gagaagcaat atggctgaac
     6001 gattttggga gaacttgtcc attattttgg ctgaaagaaa tattagctgg attgagttaa
     6061 ccagaaaaat gtttgcggga gagtttcact atccaagtga attgaaccgt ttgtatcaaa
     6121 agatacgcca ctacaagatg gaacaacgaa tgcctcaaag tccatgggta gaaaggattg
     6181 tgcaggtatt agatttagat tatgaagatt tatttcggag gtaactatga aaagaatcat
     6241 tccagtttat atattccaac aagtaaatgt cctattggta tctctatact tactgaaatt
     6301 gctttgtatc ggtgagttaa ctatactaca gattctctat ggtgcgtcac tcatttcttt
     6361 tttatggatg tatggccaac gcaaacaagc tcataaggtc aatatgaaat ctaggatgaa
     6421 atggcttggt attggattca ttagcctact gattataagt ctatgtttta gcctaatcca
     6481 tgctcaagga accacgaatc aagcaaactt aattggactt caacatcaag ttccttggtt
     6541 ttcattttta ttgttcttaa tcaatgcgag tatggttgaa gaatttctgt atcgagaaat
     6601 tttatggaac ttggttagaa aattagatat tcgagttgct ttgacaagtg ttttatttgc
     6661 cttagcacat catccaggaa ccattctagc ttggtgttta tatgtttcac ttgggatgtt
     6721 tttagggctt gtacgctaca aatcggactt atggggcagt atggggctac atttggtgtg
     6781 gaacctatca gtctatgtct tatttttgct ttaataatag ctgttctgtc ttacgtatgg
     6841 attaattttg aaataaaaat agcataaaaa tctagttatc cgcataaaaa ctggacttat
     6901 cacactttat caaggtcaaa accactcaat ttactactaa tttactactt atgaatgagc
     6961 tttgatacga cgatttatcc ttgaaaagtg aagatataaa gatacttcca ataaaatttg
     7021 aatatttaat aggtagacac ttcaaaaaat gaggtgtcta tttttttacc cgattttgaa
     7081 aggaagtgaa cttatgaaaa caaaaaatca agaatcaaaa ggtcgttccc cactctttaa
     7141 gaccatcaaa cattcattca gccaataaaa aagaaaggat aggtaaaaat atggaactta
     7201 aatttgtgat tcccaacatg gaaaaaacat tcggcaattt agaatttgct ggcgaggata
     7261 aagtcgttca gcgaagaatc aacggacggc taactgtctt atcaagaagc tataatctct
     7321 attctgatgt tcaaagagca gatgatattg tggtggtgct tcctgctgaa gctggcgaaa
     7381 aacatttcgg ctttgaggaa cgtgtgaagt tagtcaatcc acgtattacc gcagagggct
     7441 acaaaatcgg cactcgtggt tttacaaatt accttttaca tgctgacgac atgataaaag
     7501 aataaagaaa gagaggaaaa atgatgagat tagcaaatgg cattgtatta gataaagaca
     7561 cgacttttgg agaattgaaa ttctctgctc tacgtcgtga agtgagaatc caaaatgaag
     7621 acgggtcggt ttcagatgaa atcaaggaac gtacctatga cttaaaatcc aaaggacaag
     7681 gacgcatgat tcaagtaagt attcctgcca gcgtgccttt gaaagagttt gattataacg
     7741 cacgggtgga acttatcaat cccattgcgg acaccgttgc tactgccacc tatcaaggag
     7801 cagatgttga ctggtatatc aaggcagacg atattgtgct gacaaaggat tctagttcat
     7861 tcaaagctca accacaagca aagaaagaac cgacacaaga caaatagtcg ctaggtagaa
     7921 aggagacttt ttcgcatgaa acagcgtggt aaaaggattc gcccatctgg taaagattta
     7981 gtctttcatt ttacgatagc gtcactcctg cctgttttcc tgctggttgt cggactgttt
     8041 catgtgaaga caatccagca gatcaactgg caggatttta acctatcaca agcagataag
     8101 attgacattc cctatttaat tatcagtttc agtgtcgcaa ttcttatctg cttgctggta
     8161 gcgtttgtat tcaaacgggt tcgctatgat acggttaaac aactttacca ccgtcaaaaa
     8221 ctggcaaaga tgatacttga aaacaagtgg tatgaatctg aacaggtcaa aacagagggt
     8281 ttctttaaag atagtgctgg tcgtacaaaa aagataacct acttccctaa aatgtattat
     8341 cgacttaaaa atggcttgat acagatacgg gtggaaatca cgctgggaaa atatcaagac
     8401 caactcttac acttggaaaa gaaattagag agtggcttgt actgtgagct gacggataaa
     8461 gagttaaagg attcctatgt ggaatatact ttgctctatg acaccatagc cagtcgtatt
     8521 tctattgatg aagtagaagc taaagatggt aaacttcgct taatgaaaaa cgtatggtgg
     8581 gaatatgata agctccctca tatgttgatt gctggtggta caggtggcgg taaaacttac
     8641 tttatactga cactgattga agccttgctt catacagatt caaaactgta tattcttgac
     8701 ccgaaaaatg ctgaccttgc ggacttaggt tctgtgatgg caaatgtcta ctatagaaaa
     8761 gaagacttgc tttcttgcat tgaaacattc tatgaagaaa tgatgaaacg tagtgaggaa
     8821 atgaagcaga tgaagaacta taagactggc aaaaattatg cttacttagg tctcccggca
     8881 cacttcttaa tctttgatga atacgtcgct ttcatggaaa tgctgggaac aaaagaaaac
     8941 accgcagtta tgaataagct gaaacagatt gtcatgttag gtcgtcaagc tggcttcttt
     9001 ctaatactgg cttgtcaacg tccagacgca aaatatttag gcgacggaat ccgtgatcag
     9061 tttaatttca gagtggcttt aggtcgtatg tctgaaatgg gctatggcat gatgtttggc
     9121 agtgacgtac aaaaggattt cttcttaaag cgaatcaaag gtcgtggcta tgttgatgta
     9181 ggaacaagtg tcatatcaga gttttatact ccccttgtac caaaaggata tgatttcttg
     9241 gaggaaatta aaaagttatc caacagcaga cagtccacgc aggcgacgtg cgaagcggaa
     9301 gtcgcaggtg tggactgatc ttgctggctg gtgtggcaat agccacgcca gcacttaacc
     9361 ccccgtatct aacagggggg tacaaatcga caggaaacag tcaaaaaaac attagaaaat
     9421 cctttggtta caagggattt acaaaatttc agcgtatgtc aaatgggctt taaaagttga
     9481 catacgcctt tttgattgga gggattttta ctgaatgaac aaacttggtt acagcattta
     9541 aaagaaaaac gcttggctta tggactatct caaaaccgtt tagctgttgc gactggtatt
     9601 acaaggcagt atctaagcga tattgaaaca ggaaaagtca agccatcaga ggatttacag
     9661 cagtcccttt gggaagctct ggaacgcttc aatcccgacg ctccccttga aatgctgttt
     9721 gattatgtaa ggattcgctt tccgacaaca gacgtacagc aggtggtcga aaacatctta
     9781 caactgaaac tgtcctattt tcttcatgag gactatggtt tctattctta ttcagagcat
     9841 tatgctttag gcgacatatt cgtcctttgc tcccatgaac tggacaaagg agttctggtg
     9901 gaattgaaag gtcgtgggtg cagacaattt gaaagctatc ttctggcaca acaaagaagc
     9961 tggtatgagt tctttatgga cgttttggtg gctggcggtg tgatgaaacg ccttgacctt
    10021 gccattaacg ataagacagg gattttgaat atccctgtac tcactgaaaa gtgccaacag
    10081 gaagaatgta tctccgtctt ccgcagtttt aaaagctatc gcagtggcga actggtacgc
    10141 aaagaggaaa aggaatgtat gggaaacacc ctctatatcg gttcattaca aagtgaagtt
    10201 tatttctgta tctatgaaaa ggactacgag cagtacaaga aaaatgatat tcccattgaa
    10261 gacgcagaag taaaaaaccg ttttgagatt cgattgaaaa atgagcgtgc ctattatgca
    10321 gtccgtgatt tactcgtcta tgacaatcca gagcataccg cctttaaaat tatcaatcgg
    10381 tatatccgtt ttgtagataa agacgattcc aaacctcgtt ctgattggaa actgaatgaa
    10441 gaatgggctt ggtttattgg gaacaatcgt gaacgattaa aactaaccac aaaaccagag
    10501 ccttactcct tccaaaggac gctgaactgg ctatctcatc aagttgcccc gaccttaaag
    10561 gttgcgatta aacttgatga aatcaaccag acgcaggttg taaaagacat tctcgaccat
    10621 gcgaaactga cagaccgaca caagcagatt ttgaagcaac agtcagtaaa agaacaggac
    10681 gtgataacaa caaaaaaata actcaaatac aaattcattg aatatagaga ggagaacatt
    10741 tttatgaatt ttggacaaaa cctttataac tggtttctat caaacgctca atcactggtg
    10801 cttttagcaa tcgttgtgat tggcttgtat cttggcttca agcgtgagtt tagcaaactg
    10861 attggctttt taattattgc gattattgcg gttggcttag tcttcaacgc tgctggagta
    10921 aaagacattt tactagagct attcaatcgc attattggtg cttaaataaa accgttcttt
    10981 tgtggaatat aagtggtttt cttatgttcc gcaaaggaat ggtacaccaa acgaagtgcg
    11041 gtagggattt ttgaatctct acaaagaaag gacgtgaata tatggacgat atgcaagtct
    11101 atattgcgaa tttaggcaaa tacaatgagg gcgaattggt cggtgcgtgg tttacctttc
    11161 ccattgactt tgaggaagtc aaagagaaaa tcggcttgaa tgatgaatat gaggaatacg
    11221 ccattcatga ctacgagtta ccctttacgg ttgacgaata cacttccatt ggcgaactca
    11281 atcgactatg ggaaatggta tcggaattac ccgaagaatt acaatcggag ctatctgctc
    11341 tgctcactca tttttcaagc attgaagaac taagcgaaca tcaagaggat attatcattc
    11401 attccgattg tgatgatatg tatgacgtgg cacgctacta cattgaagaa acgggtgctt
    11461 taggcgaagt accagctagt cttcaaaact atattgatta tcaagcctat ggtcgggatt
    11521 tagacctttc aggaacgttt atctcaacca atcatgggat ttttgaaatc gtctattaaa
    11581 tctgtcggta cattactact ggcagatttt ctattttacg gggtggctca atcagctacc
    11641 cctatttttt atgaaaggat tgattacatg aagaaaatac gaagctatac cagtatctgg
    11701 tctgtggaaa aggtactgta ttctatcaat gattttagac ttccgtttcc cataaccttt
    11761 acgcaaatga catggtttgt cgtgtcactc tttgcagtga tgatacttgg caacttgccc
    11821 cctctttcca tgatagaggg agcatttctc aaatactttg ggattcctgt ggctttcaca
    11881 tggtttatgt ctacaaaaac ttttgatggt aaaaagcctt atggattttt gaagtctgtc
    11941 attgcttatg cactgcgacc aaagctgacc tatgcaggaa aaaaagtaac gcttggcaga
    12001 aaccagccac aagaagccat tacagcagtt aggagtgaat tttatggcat atccaattaa
    12061 atacattgaa aacaatctcg tctggaataa agacggggaa tgttatgctt actatgagct
    12121 tgttccttac aattactcat ttctcagtcc agaacagaaa atacaagtgc atgattcttt
    12181 cagacagctt atcgcacaaa atcgtgatgg caaaattcat gctttacaaa tcagtacaga
    12241 atccagcata cgttctgcac aagagcgttc caaaaatgaa gtcactggca agctcaaagc
    12301 ggttgcctat gacaaaatcg accaacagac agacgcttta atatccatga ttggcgaaaa
    12361 tcaagtgaac taccgtttct ttatcggctt taagttgctt ctcaacgatc aggagttttc
    12421 tatgaaaagt cttaccgttg aagcaaaaaa tgctttgtct gattttgtct atgatgtgaa
    12481 ccataagctg atgggcgatt ttgttagtat gagtaatgat gaaatcctgc gatttcagaa
    12541 gatggaaaag ctcttagaaa ataaaatctc tcgtcgtttc aaaatccgca ggttagataa
    12601 ggacgacttc ggctatctga ttgaacacct ttacggacag acaggcactg cctatgaaga
    12661 gtatgagtac catctatcaa agaaaaagct ggataatgaa acgctgatta aatactatga
    12721 cttgattaag cctactcgct gtttggtgga agaaaaacag cgatatttga aaatccagca
    12781 ggaagatgaa accgtctatg tagcttactt taccattaac agcattgtcg gagaactgga
    12841 cttcccgtcc tctgaaatct tctactacca gcaacagcaa tttacattcc cgattgatac
    12901 gtcaatgaat gtggaaattg tagcgaatcg taaagcccta tctactgtcc gcaataaaaa
    12961 gaaagaactg aaagacttgg ataaccacgc ttggcaaagt gataatgaaa ccagctccaa
    13021 tgtggcggaa gctctggaaa gtgtgaatga gctggaaacc aatttagacc aaagcaagga
    13081 atctatgtac aagctgtctt atgtggtaag ggtatcagca aatgatcttg acgaactcaa
    13141 acgtcgttgt aatgaagtga aagattttta tgacgattta agcgtaaaac tggtacgacc
    13201 atttggggat atgctcggct tacatgaaga atttttacct gccagcaagc gttatatgaa
    13261 tgattatatt caatacgtga cctctgattt cctcgctggt ttaggttttg gtgctactca
    13321 aatgctgggg gaaaatgagg ggatttatgt tggctacagc ttagatactg gacgcaatgt
    13381 ctatctgaaa cctgctcttg ccagtcaagg ggttaagggt tcagtaacca atgcgttagc
    13441 gtcggctttt gttggttcgc tgggtggtgg taaatccttt gcgaataacc ttatcgtcta
    13501 ttatgcggtg ctttatgggg cacaagcagt gattgtagac ccaaaagcag aacgtggcag
    13561 atggaaagaa accttgccag agatttccca tgaaatcaat atcgtcactc tgacttctga
    13621 tgagaaaaac aaaggcttac ttgaccctta tgtgattatg aaaaatccca aagattctga
    13681 atcactggct attgatattc tgacattcct tacggggatt tcctctcgtg atggggaacg
    13741 cttcccaatc cttagaaaag ccattcgtgc agtaaccaat agtgaagtac gagggttgat
    13801 gaaagtgatt gaggaattac gggttgagaa tacgccacta agtaccagta tagccgacca
    13861 tatcgaaagt tttacagact atgactttgc acatttatta ttcagtaatg gttatgtgga
    13921 gcagtctatc agcttagaaa aacaactgaa cattatacag gttgcggact tggtacttcc
    13981 cgacaaggaa acttcctttg aggaatatac cactatggag cttttatccg ttgctatgct
    14041 gattgtcatt agtacctttg ctttagactt tatccataca gaccgaagca ttttcaagat
    14101 tgtagattta gacgaagcat ggagcttttt acaggtagca caaggaaaaa cactatctat
    14161 gaagctggtt cgggctggtc gtgctatgaa cgctggggta tatttcgtga cccaaaatac
    14221 agacgacctc ttagatgaaa aactgaaaaa taacctcggc ttaaaatttg catttcgttc
    14281 cactgacctt aacgagatta aaaagacctt agcctttttt ggtgtagacc cagaggacga
    14341 aaacaatcag aagcgattgc gtgatttgga aaacgggcaa tgccttatca gtgatttata
    14401 tggtcgtgtc ggtgtgatac agttccaccc tgtatttgaa gaactgctcc atgcctttga
    14461 taccagacca cctgtgcgaa aagaggtgta aatgtgaaac catcaatagt aaacagaata
    14521 aaatcaaact ggacgctgaa acgtctaggt aaagtggcaa tgacagtggc tttcacactt
    14581 gtgattgcca tttttctttt agccatgctg ggaacggtgg ttcaagctgc gggcttggta
    14641 gatgatacgg tcaatgtggc aaatgaatac agccgatacc cacttgaaaa ctatcaactg
    14701 gatttttatg tggataatag ctggggctgg cttccgtgga actggtcgga cgggattgga
    14761 aaacaggtca tgtatggact atatgccatt accaatttta tttggacaat cagtttgtat
    14821 gtttccaatg cgacaggtta cttagtacag gaagcctatt ccttagactt catttccgct
    14881 acagcagatt ccattggtaa gaatatgcag accttagctg gtgtgagtgc aaacggattt
    14941 tcaacagagg gtttctatgt tggattcctc ttactcttga ttttggttct tggggtttat
    15001 gttgcctata cgggactgat aaagagagaa accacaaagg caattcatgc cattatgaat
    15061 tttgtgctgg tgtttatcct atcggcttcc tttattgcct acgctcccga ctacattaaa
    15121 aaaatcaatg acttttcatc agacatcagt aatgccagtt tatcacttgg cacgaagatt
    15181 gtcatgcccc attccgatag tcaaggcaag gacagcgtgg acttaatcag agatagcctg
    15241 ttttccatac aggttcagca accgtggcta ctgcttcaat acaacagttc agacattgaa
    15301 agtatcggta ttgaccgtgt ggaaagcctg ctctccacca gcccagattc caacaatggc
    15361 gaagacagag aaaaaattgt tgcggaagaa attgaagaca gaagcaatac caatctaacc
    15421 attacaaaga ccattaaccg tttaggtaca gtcttcttcc tatttgtctt caatattggg
    15481 atttccatat ttgtattcct attaacagga atcatgattt tctcgcaggt actttttatc
    15541 atctatgcta tgtttctgcc tgtgagcttt attttaagca tgattccatc atttgatggt
    15601 atgtcaaaac gagccataac aaagctcttt aataccattt tgacacgagc tggaatcaca
    15661 ttgattatta cgacagcatt tagtatttca accatgctct ataccttatc ggctggttat
    15721 ccgttctttt tgattgcttt tctacagatt gtgacctttg caggaatcta cttcaagctg
    15781 ggcgatttaa tgagtatgtt ttctctacag agtaacgatt ctcaaagtgt gggaagtcgt
    15841 gtgatgagaa aacctcgtat gcttatgcac gctcacatgc accgtctaca gcggaaactt
    15901 ggacgttcca tgactactct aggggctggg tctgccattg ttacaggtaa aaaaggacag
    15961 tcgggttcgg ggagttctgc aaggacacaa gcagatcact cccgaccaga cggaaaggaa
    16021 aaatcaacac ttggaaaacg tatcggtcaa accatcggta cagtagctga taccaaagac
    16081 agaatggtag acactgctag tggtttgaaa gaacaggtta aagatttgcc gaccaatgca
    16141 agatatgcag tatatcaagg aaaatccaaa gtaaaagaga atgtccgtga tttaaccagt
    16201 agtatttctc aaaccaaagc ggacagagcc agtggacgca aggaacagca ggaacaaagg
    16261 cgaaaaacca ttgcgaagcg tcgctctgaa atggaacagg tcaaacagaa aaaacagcct
    16321 gcttcttctg ttcatgaaag accgactaca agacaagaac aatatcatga tgaacagacc
    16381 tcaaaacagt ctaatattca gacttcatat aaggaatctc aacaagccaa acaagagcgt
    16441 ccagcagtta agtccgattt ttcaagtcca aaagtggaac gccaaggcaa taccgttcaa
    16501 gaaaaaaccg ttcaaaagcc agcaacttca accactacag cagatagaac ttcacaacgt
    16561 ccaatcacaa aagaacgtcc gtctactgtt caaagagtac cactacaaaa tacaagaagt
    16621 agaccaccaa tcaaaaccgc caccattaag aaagtcggta agaaaccatg aagttgaaaa
    16681 ctttagtgat tggtggttct ggattattct tgatggtctt ctcactgctt ctgtttgttg
    16741 ccattttatt ttcagatgaa caggacagcg gaatttccaa tattcattat ggaggtgtga
    16801 atgtttccgc agaagtgctg gctcataagc ctatggtaga aaaatatgcc aaagaatatg
    16861 gcgttgaaga atatgtcaac atacttcttg cgattataca ggtggaatcg ggcggtactg
    16921 cggaagatgt tatgcagtcc tcggaatccc tcggtcttcc acctaattca ttgagtacag
    16981 aagaatccat taagcaaggt gtgaagtatt tcagtgaatt attagccagt agcgaaaggc
    17041 tcagtgtaga tttagaatcg gttatccagt cctacaatta tggtggtggt ttcttagggt
    17101 atgtggctaa tcgtggaaat aaatatacct ttgaactggc tcaaagtttc tcaaaagagt
    17161 attcaggtgg cgaaaaagtg tcttacccca atcccatagc catacctatc aatgggggct
    17221 ggcgatacaa ctatggcaat atgttttatg tgcaactggt aacgcagtat cttgtcacaa
    17281 cagagtttga tgatgatacg gtacaagcca tcatggacga agcactgaaa tatgagggct
    17341 ggcgatacgt ttacggtgga gcttccccga ctacttcttt tgattgtagc ggactgacac
    17401 aatggacgta tggaaaagct ggaattaact taccacgaac cgcacaacag caatatgatg
    17461 tgacccagca tatcccacta tcggaagcac aagctggcga tttggttttc tttcattcta
    17521 cctataacgc tggctcttat attactcatg ttgggatata ccttggcaat aaccgtatgt
    17581 ttcatgcagg cgacccaatc ggttatgccg acttaacaag cccctactgg caacagcatt
    17641 tagtgggagc aggacgaatc aaacaatgag aaaggaagat ttaatgatga aatttagaaa
    17701 aaatcagaat aaagaaaaac agataccaaa ggaaaagaaa cctcgtgtct actataaggt
    17761 caatcctcat aaaaaggttg tgattgcctt gtgggtactt ttagggctta gtttcagctt
    17821 tgcgatattc aagcacttta cagctataga tactcatact attcacgaaa caactatcat
    17881 agaaaaggaa tacgttgata ctcatcatgt agaaaatttt gtagagaact ttgcgaaagt
    17941 ctactattca tgggagcaat ccgataagtc cattgataat cgaatggaaa gtctaaaagg
    18001 ctatctgaca gatgaacttc aagctctcaa tgttgataca gtacgcaaag atattcctgt
    18061 atcgtcttct gtaagaggat ttcagatatg gacggtagag ccaactggcg acaatgagtt
    18121 taatgtaacc tacagtgtag accagctcat tacagaggga gaaaatacaa agaccgtcca
    18181 ctctgcttat atagtgagtg tctatgtaga tggttctgga aatatggtac tggttaagaa
    18241 tccgaccatt accaacatac ctaagaaatc aagttataaa ccaaaagcca ttgaaagtga
    18301 ggggacggtt gattccatta caaccaatga aatcaatgag tttttaacga cgttcttcaa
    18361 gctctatcct acagcgacag ccagtgaact ttcctactat gtgaatgacg ggatattaaa
    18421 accaatcgga aaagagtaca tctttcaaga actggtaaat cctattcaca atcgtaagga
    18481 taatcaagtc acggtatcgc tgacagtgga gtatatcgac cagcagacca aagcaacgca
    18541 ggtatctcaa tttgatttgg tacttgaaaa gaacgggagt aattggaaga ttatagaata
    18601 acaaatattg gtacattatt acagctattt tgtaatcacg tactctcttt gataaaaaat
    18661 tggagattcc tttacaaata tgctcttatg tgctattatt taagtatcta tttaaaagga
    18721 gttaataaat atgcggcaag gtattcttaa ataaactgtc aatttgatag tgggaacaaa
    18781 taattggatg tcctttttta ggagggctta gttttttgta cccagtttaa aataccttta
    18841 tcatgtgatt ctaaagtatc cggagaatat ctgtatgctt tgtatgccta tggttatgca
    18901 taaaaatccc agtgataaga gtatttatca ctgggatttt tatgcccttt tgggcttttg
    18961 aatggaggaa aatcacatga aaattattaa tattggagtt ttagctcatg ttgatgcggg
    19021 aaaaactacc ttaacagaaa gcttattata taacagtgga gcgattacag aattaggaag
    19081 cgtggacaga ggtacaacga aaacggataa tacgctttta gaacgtcaga gaggaattac
    19141 aattcagaca ggaataacct cttttcagtg ggaaaatacg aaggtgaaca tcatagacac
    19201 gccaggacat atggatttct tagcagaagt atatcgttca ttatcagttt tagatggggc
    19261 aattctactg atttctgcaa aagatggcgt acaagcacaa actcgtatat tatttcatgc
    19321 acttaggaaa atggggattc ccacaatctt ttttatcaat aagattgacc aaaatggaat
    19381 tgatttatca acggtttatc aggatattaa agagaaactt tctgccgaaa ttgtaatcaa
    19441 acagaaggta gaactgtatc ctaatatgtg tgtgacgaac tttaccgaat ctgaacaatg
    19501 ggatacggta atagagggaa acgatgacct tttagagaaa tatatgtccg gtaaatcatt
    19561 agaagcattg gaactcgaac aagaggaaag cataagattt cagaattgtt ctctgttccc
    19621 tgtttatcac ggaagtgcaa aaaacaatat agggattgat aaccttatag aagtgattac
    19681 gaataaattt tattcatcaa cacatcgagg tcagtctgaa ctttgcggaa aagttttcaa
    19741 aattgagtat tcggaaaaaa gacagcgtct tgcatatata cgtctttata gtggcgtact
    19801 gcatttgcga gattcggtta gaatatcgga aaaggaaaaa ataaaaatta cagaaatgta
    19861 tacttcaata aatggtgaat tatgtaaaat cgataaggct tattccgggg aaattgttat
    19921 tttgcagaat gagtttttga agttaaatag tgttcttgga gatacaaagc tattgccaca
    19981 gagagagaga attgaaaatc ccctccctct gctgcaaacg actgttgaac cgagcaaacc
    20041 tcaacaaagg gaaatgttac ttgatgcact tttagaaatc tccgacagtg acccgcttct
    20101 gcgatattat gtggattctg cgacacatga aatcatactt tctttcttag ggaaagtaca
    20161 aatggaagtg acttgtgctc tgctgcaaga aaagtatcat gtggagatag aaataaaaga
    20221 gcctacagtc atttatatgg aaagaccgtt aaaaaaagca gagtatacca ttcacatcga
    20281 agttccaccg aatcctttct gggcttccat tggtctatct gtagcacagc ttccattagg
    20341 gagcggagta cagtatgaga gctcggtttc tcttggatac ttaaatcaat cgtttcaaaa
    20401 tgcagttatg gaggggatac gctatggctg tgaacaagga ttgtatggtt ggaatgtgac
    20461 ggactgtaaa atctgtttta agtatggctt atactatagc cctgttagta ccccagcaga
    20521 ttttcggatg cttgctccta ttgtattgga acaagtctta aaaaaagctg gaacagaatt
    20581 gttagagcca tatcttagtt ttaaaattta tgcgccacag gaatatcttt cacgagcata
    20641 caccgatgct cctaaatatt gtgcgaacat cgtagacact caattgaaaa ataatgaggt
    20701 cattcttagt ggagaaatcc ctgctcggtg tattcaagaa tatcgtagtg atttaacttt
    20761 ctttacaaat ggacgtagtg tttgtttaac agagttaaaa gggtaccatg ttactaccgg
    20821 tgaacctgtt tgccagcccc gtcgtccaaa tagtcggata gataaagtac gatatatgtt
    20881 caataaaata acttagtgta ttttatgttg ttatataaat atggtttctt gttaaataag
    20941 atgaaatatt ttttaataaa gatttgaatt aaagtgtaaa ggaggagata gttattataa
    21001 actacaagtg gatattgtgt cctgtatgtg gaaataaaac acgattaaag ataagggaag
    21061 atactgaatt aaaaaaattc cccctctatt gtccgaaatg cagacaagaa aatttaattg
    21121 aaataaagca gttcaaagta actgtgatta cagagccaga cgcaaagacg cagagccgat
    21181 aaaatgagat taatacaatc tcattttatc ggctctttcc gttatgtatg gattctttta
    21241 attagtcttc gatgtttctt gcttcgttga taccgctggc taaagattcc attaaggata
    21301 gttctttgtc tgtaaagcta tccatgtatt tctctatctg taatcgtcgg gtgcttttta
    21361 ccaagttatt agcaggtagg ggtcccgagc gcctacgagg aatttgtatc gataagaaat
    21421 agatttaaaa atttcgctgt tattttgtac atttaacttg acggtgacat ctctctattg
    21481 tgagttatta gtggtacagt tttcaaccgt tttaattata aaaaagtggt gcatttttaa
    21541 attggcacaa acaggtaacg gttattgcag gtgtatttct tatctatggg tttaacatgg
    21601 attttatcat taaaatcatg agtattgtcc gagagtgatt ggtcttgcgt atggttaacc
    21661 ctaaagttat ggaaataaga cttagaagca aacttaagag tgtgttgatt gtgcattatc
    21721 ttaaaatttt gtataatagg aattgaagtt aaattagatg ctaaaaattt gtaattaaga
    21781 aggagggatt cgtcatgttg gtattccaaa tgcggaatgt agataaaaca tctactgttt
    21841 tgaaacagac taaaaacagt gattacgcag ataaataaat acgttagatt aattcctacc
    21901 agtgactaat cttatgactt tttaaacaga taactaaaat tacaaacaaa tcgtttaact
    21961 tctgtattta tttatagatg taatcacttc aggagtgatt acatgaacaa aaatataaaa
    22021 tattctcaaa actttttaac gagtgaaaaa gtactcaacc aaataataaa acaattgaat
    22081 ttaaaagaaa ccgataccgt ttacgaaatt ggaacaggta aagggcattt aacgacgaaa
    22141 ctggctaaaa taagtaaaca ggtaacgtct attgaattag acagtcatct attcaactta
    22201 tcgtcagaaa aattaaaact gaacattcgt gtcactttaa ttcaccaaga tattctacag
    22261 tttcaattcc ctaacaaaca gaggtataaa attgttggga atattcctta ccatttaagc
    22321 acacaaatta ttaaaaaagt ggtttttgaa agccatgcgt ctgacatcta tctgattgtt
    22381 gaagaaggat tctacaagcg taccttggat attcaccgaa cactagggtt gctcttgcac
    22441 actcaagtct cgattcagca attgcttaag ctgccagcgg aatgctttca tcctaaacca
    22501 aaagtaaaca gtgtcttaat aaaacttacc cgccatacca cagatgttcc agataaatat
    22561 tggaagctat atacgtactt tgtttcaaaa tgggtcaatc gagaatatcg tcaactgttt
    22621 actaaaaatc agtttcatca agcaatgaaa cacgccaaag taaacaattt aagtaccgtt
    22681 acttatgagc aagtattgtc tatttttaat agttatctat tatttaacgg gaggaaataa
    22741 ttctatgagt cgcttttgta aatttggaaa gttacacgtt actaaaggga atgtagataa
    22801 attattaggt atactactga cagcttccaa ggagctaaag aggtccctag cgcctacggg
    22861 gaatttgtat cgataaggaa tagatttaaa aatttcgctg ttattttgta caataaggat
    22921 aaatttgaat ggtaccataa acgaccgttt atggtacctt ttcattttcc tgctttttct
    22981 aaatgttttt taagtaaatc aagtaccaaa atccgttcct ttttcatagt tcctatatag
    23041 ttatacttaa tgagttatgg tacatttaaa ttataaaatt aaggaggttt ttttatgatt
    23101 tttggctatg ctcgagtgag tacggatgat caaaatctta gtttacaaat tgatgcactt
    23161 actcattatg gaattgataa attatttcaa gaaaaagtaa ctggtgcgaa aaaagaccga
    23221 ccgcaattag aagaaatgat caacctacta cgtgaaggag attctgttgt catttacaag
    23281 ttagatcgaa tttcacgatc aactaaacat ttgattgaac tttctgaatt atttgaagaa
    23341 cttagtgtca attttatatc tattcaagat aacgtagata cttcaacgtc tatgggaaga
    23401 ttctttttcc gagttatggc tagtttagca gaactggaac gggatattat tattgaacga
    23461 actaactctg gtcttaaggc agccagagtc cgaggaaaaa aagggggccg tccaagtaaa
    23521 ggtaagctat caattgattt agctttaaaa atgtatgaca gcaaagagta ttctattcgt
    23581 caaattcttg atgcctctaa attaagcaaa acaacctttt accgttacct caataaaagg
    23641 aatgcttaag atatggctat gaaaagaatt ttaactactt cacagcgtga acaacttctt
    23701 tctgtagacc acttatcaga agaggatttt aaagcgtatt ttagtttttc tgattatgat
    23761 ctggaggtta ttaatcaaca ccgtggaaag gtcaataaac taggatttgc gatacaactt
    23821 tgtttggccc ggtatcctgg gtgttcttta agtaattggc cgattaaatc aaccagacta
    23881 acttcttatg tgagtcgaca gctccatctt gatgcaattg atttaaattc atatgatcat
    23941 agaaatacac gtgcaaatca cttcaacgag atcttagaag tattcaacta tcatcgattc
    24001 ggtagtgcta atacacaaaa acagttaata gaatatttaa ttgaactagc tttagaaaat
    24061 gatgactcta tctatctaat gaaaaaaaca attgatttct taactcgaaa aagaattatt
    24121 tttccatcta tagctacact tgaagacatt ataagccgct gtcgagataa agcagaaaac
    24181 aacttatttt caatattact ctgttcatta acagatatac aaattgaaaa actagagagt
    24241 ttgtttcaaa tttatgaaga gacgaaaata actaaactcg cttggctaaa agacattcca
    24301 ggtaaggcaa atccagaaag ctttatgagt atttgtaaaa aagtggaagt gattgcttcc
    24361 atgggactcg ggacaattaa tgtctcccat attaatcgga acaggtttct tcagctagct
    24421 agactagggg aaaattatga tgcatatgac ttctcccgtt ttgagcttga aaaaagatac
    24481 tctttactta ttgctttttt agtcaatcat catcaatatc tgatcgatca actgattgag
    24541 attaatgacc gcattttagc aagtattaaa cgcaaaggga cacgtgattc acaagaacag
    24601 ttaaaagaaa aaggaaaatt ggctactaaa aaattggaac attatgcttc tttaattgat
    24661 gctcttcact ttgcaaaaga taatgatagt aatccttttg acgaaattga acgaatcatg
    24721 ccttgggaag atttagtaca agatggagaa gaagctaaaa aaattacagg taataaaaat
    24781 catggctatt tagaaatggt tcgaaataaa gctaattacc tccgaagata cacgccaatg
    24841 ttattgagga ccctttcgtt caaagcaact ccggcagcaa atccagtcct catggcccta
    24901 actcaactaa ctgatttaca caatagtggt aaaagaaaaa taccggcaga tacttctact
    24961 gattttgtga gtaaaaaatg gaaaagcctt gttcggccag aagaggggaa aatagatcgg
    25021 tcttactatg agttagtagc tttcaccgag ctaaagaaca atattcgatc aggagatatt
    25081 tcagttgaag gaagtatgat ccatcgaaat attgatgatt acttagttga tttatctgct
    25141 tgtattgatt cagaaactat tccagacacg tttgaggact atttaaagga tcgggaaata
    25201 attttagatt tacagcttca attttattcg acagttgata agagaatttc aagagcaaac
    25261 cttaaaaagt tggaaaaagt tacacctagc gaagcagaaa tatatagaaa aaaactttat
    25321 tcaataattc ctaagataag gcttagtgat cttttaattg aggtggacag ttggaccaac
    25381 ttttcacaag aatttagtca tgattctaca gggaaaccgc cgagtgaaca agaaagaaaa
    25441 attatttttg ctgctttgct gggtttaggg atgaatattg gtcttgaaaa aatggcccaa
    25501 tcaactcctg gaatttctta ttctcagtta gccaatgcca aacaatggcg cttttataaa
    25561 gaagctctga ctcgtgctca atctgttttg gttaattatc agttaaagct tcctgttgca
    25621 gacttttggg gtgaaggaaa aaccactgct tcagacggaa tgcgcgtccc agtgggcgtc
    25681 tcagctctaa aatccgatgt taatccacat tacaaaagta tggaaaaagg agctacaatg
    25741 attcgatcaa taaatgatag gcatacgact catcatatcg aggttgcttc aactaataca
    25801 agggaagcta ctcataccct tgatggccta ctttatcatg aaacagatct agatattgag
    25861 gaacatttta ctgatacaaa tgggtattct gatcaggtgt ttggaatgac cgcattacta
    25921 ggctttgatt ttgaacctcg catcagaaat ataaaaaaat cacaattatt ttctatcaaa
    25981 tcaccttcct actaccctaa cttatcagaa gatataagcg gaaaaatcaa tgtaaaaatt
    26041 attgaagaaa actatgatga aattaaacga atcgcctatt cgattcaaac aggaaaagta
    26101 tctagttctt tactattagg aaagctaggc tcatacgcac gtaagaatag agtagctctt
    26161 gcactgagag aactaggtcg cattgaaaag agcattttta tgatagatta tattacagat
    26221 agtgagctac ggcgaaggat cactcatgga ctaaataaga cagaagcgat taatgcttta
    26281 gctagagaac tattttttgg gcgacgcgga aaatttatgg agcgcgatat tcgccgacaa
    26341 cttcaaagtg ctagtgcgct taatgtgtta ataaatgcaa taagtatatg gaacgccgtc
    26401 tacttacaag cagcttataa ttatctcgtc aaaatagatc ccgaagtaac taagtatatg
    26461 aagcatgtat ctcctattaa ttgggagcat atcacttttc ttggagagta taaatttgac
    26521 ttgttatcta ttcctaaaca cttaagagaa ttgaatataa aaaataaata ggccttgaaa
    26581 cattggttta gtgggaattt gtacccctta tcgatacaaa ttcccactaa gcgctcggga
    26641 ccccaggtaa gaaaaattca tcaacggaaa catgaagtaa cgatacaagg tcataaagaa
    26701 cttgtatgct ggggtgttgc cctttatttt caatattagt taagtaccgt gggtcaattt
    26761 caatcaatgc tcccacttgt tcacgagtta aacctcgttt caatcgagct tctttaatgg
    26821 ctaaaccaaa ggctctaaaa tcatatttat cttctttttt acgcatagta gaccacctct
    26881 atacatttta ttgttcctac tgaattaaaa acaggtatag aaaaacgtgt tatatggttt
    26941 ataggtttat atttaataaa aagcactact aaacgccaat aaaaaaaacc gttatatggt
    27001 agtgctattt acgctgttaa aatattgtat attacttcca aatggcggtt tgttggaggt
    27061 caacgtcgcc atgaagtaca tcatatacaa taaatttcct tacattgggt tcttgtcaaa
    27121 aaaagtcgtc tatctgcaat agataagtac gtccaccaat gtggttttat aaatcatata
    27181 gatagaataa cagaagcatg taaacagaga aataaatctg tttatatgct tttttggcta
    27241 ttcagaactt ttttacaaag tttatttatc agtaatgcaa caaatccccc tttcacattg
    27301 ggactaagag tgaaaggaga taaacgagca aggctcactt cctttcctag acagaaaggg
    27361 ggtgagaaac atgaaaccat cttcttttca gaccacaata gaaaatcagt ttgactatat
    27421 ctgtaaacgt gctatggaag acgagcgaaa gaattatatg ctttatcttt caaggattgc
    27481 aaagcgtgag gtgtcctttt cggatgttgg cgattatctt gttagccagt ttgcgacaac
    27541 agataactat tcaactgact ttcagatttt tacactcaat gggttatcag taggcgttga
    27601 aaatgatttg ttgagtgaag cattacgtga gttgccagac aagaaacgtg aaattctact
    27661 gctgttttac tttatggaca tgagcgattc agaaattgca gacctgttga aattgaaccg
    27721 ttctactgtc tatcggcata gaaccagtgg actagcctta attaaaaagt ttatggagga
    27781 atttgaagaa tgaaaacaca atatcctatg attccctttc ctctcattgt aaaggcaaca
    27841 gatggcgata ccgaagcgat taaccagatt ctacatcatt acagagggta cataacgaag
    27901 cgttccctac gacttatgaa agatgaatat ggcaatcaaa gtatggtcgt tgatgaagtc
    27961 ttacgtggaa gaatggaaac cagactgatt acaaagattt tgtcatttga aattaagtaa
    28021 tatcctctct cctttcgtgg aagcgtgcta aaccattcca cgcttcccga acagggaggt
    28081 ttgttattcc accaaagcat attgagcttt caatgtgttt tgataggcta acgagccatt
    28141 gttctttgaa aactgaataa aagtaatcga atacgtttcg ataagaaaag agccaacgga
    28201 actaaccgcc atgacctatc ttataaagat agcgagcgat tcatgttagt gatccgagaa
    28261 gcaatcttta gcaggattgc ctgcaacgac attcttatcg tgataatgat actcccatac
    28321 agtcaatagt ccgagcgtga taaaaccgtc gcaggcaatg agtatggcta catgagaacc
    28381 atgcaggggt ggaactcccg tgagctttgc taaagctgtt cgattgctgg taaaacaact
    28441 tttatgaaat ccaaataagt gatttggaaa ggaggatttt atgaagcaga ctgacattcc
    28501 tatttgggaa cgttataccc taaccattga agaagcgtca aaatattttc gtattggcga
    28561 aaacaagcta cgacgcttgg cagaggaaaa taaaaatgca aattggctga ttatgaatgg
    28621 caatcgtatt cagattaaac gaaaacaatt tgaaaaaatt atagatacat tggacgcaat
    28681 ctagcgtcgc caaagggtct tgtatatgat aaaatagtat taagtcgtat caaggctctt
    28741 tccataaagg aaaggagcaa atgccatgtc agaaaaaaga cgtgacaata aaggtcgaat
    28801 cttaaagact ggagagagcc aacgaaaaga cggaagatac ttatacaaat atatagattc
    28861 atttggagaa ccgcaatttg tttactcgtg gaaacttgtg gctacagacc gagtaccagc
    28921 aggaaagcgt gattgtatct cacttagaga gaaaatcgca gagttacaga aagacattca
    28981 tgatggtatt gatgttgtag gaaagaaaat gacactctgc cagctttacg caaaacagaa
    29041 cgctcaaaga ccaaaggtta gaaaaaacac tgaaactgga cgcaaatatc ttatggatat
    29101 tttgaagaaa gacaagttag gtgtaagaag tattgacagt attaagccat cagacgctaa
    29161 agaatgggct attagaatga gtgaaaatgg ttatgcttat caaaccatca ataactacaa
    29221 acgttcttta aaggcttcat tctatattgc tatacaagat gattgtgttc ggaagaatcc
    29281 atttgacttt caactgaaag cagttcttga tgatgatact gtccctaaga ccgtactaac
    29341 agaagaacag gaagaaaaac tgttagcctt tgcaaaagct gataaaacct acagcaaaaa
    29401 ttatgatgaa attctgatac tcttaaaaac aggtcttcgt atttcagagt ttggtggttt
    29461 gacacttcca gatttagatt ttgagaatcg tcttgtcaat atagaccatc agctattgag
    29521 agatactgaa attgggtact acattgaaac accaaagacc aaaagtggcg aacgtcaagt
    29581 tcctatggtt gaagaagcct atcaagcatt taagcgagtg ttagcgaatc gaaagaatga
    29641 taagcgtgtt gagattgatg gatatagtga tttcctcttt cttaatagaa agaactatcc
    29701 aaaagtggca agtgattaca acggcatgat gaaaggtctt gttaagaaat acaataagta
    29761 taacgaggat aaattgccac acatcactcc acatagtttg cgacatacat tctgtaccaa
    29821 ctatgcaaat gcaggaatga atccaaaggc attacagtac attatgggac atgctaatat
    29881 agccatgacg ctgaactatt acgcacatgc aacattcgat tctgcaatgg cagaaatgaa
    29941 acgcttgaat aaagagaagc aacaggagcg tcttgttgct tagtagtaca aatgaattta
    30001 ctacttattt accacttctg acagctaaga catgaggaaa tatgcaaaga aacgtgaagt
    30061 atcttcctac agtaaaaata ctcgaaagca catagaataa ggctttacga gcatttaaga
    30121 aaatataaaa agataattag aaatttatac tttgtttatt tataaaaaaa ctaaatgaat
    30181 tgattttaaa gaaataaaat gctaacatat atagtagatg ttagtatttt atttctaaga
    30241 aaggagaatg atatggttga taaaagagag aaactgatga actctttcaa tcagtatggt
    30301 tttttaactt ttaaacaagt aatagatgaa aatttacact acaaaacctt attaaaaatg
    30361 gttgcagaag gaaaaatcga tgctgaagaa aaagggttat atcgcttacc tgatatttat
    30421 ttagatgagt ggtttgtcct tcagtatcga tttccaaagg gaatcttttc tttggagaca
    30481 gcactttggt tacatggttt atctttgact atccctttta acatgacgat gagttttcct
    30541 tatggtacga ataccaaaaa cattaaggaa gcagatatat gtcctattat cttacgctct
    30601 cactatagtg aaggaattat tgaaatagag cgccttcctg gtcaatttat taaagtttat
    30661 gaagttgagc gagttttggt tgaatgtcta agaccagttc atcaggtgga tcttcaaatt
    30721 attgcaccag cgtttaaaaa atattttcaa caaaataaaa ttcatttaca caaattattt
    30781 tattatgccc agctatttaa agtaactgat aagttacaat cttatacgga ggtactatct
    30841 taatgttttc aaatgcgaat agctttaaag caaaaatcaa aaacatttca aaagataagg
    30901 gaattccagc tcaacaagta caacaacatt atttaattga gcaagtgtta aagctgattt
    30961 ctactagttc ttatagagat tccttcattg taaaaggagg gtatctaata ggtcaaatga
    31021 ttggactaga taagcgaacc acaatggatt tagatgtcac tctgaaggga accgaaatga
    31081 gcagagaaaa tttgattcat atctttgaag agattctttg ttctaatact gatggatttt
    31141 cattttcagt agataagcta gaacctattc gtcaagatga tgaatatgga ggattttcat
    31201 taaaattaaa tgcaactttt gatacattaa aagaggttgt ttttattgat attactactg
    31261 gtgataaaat cacaccaaga gaaattactt attcaatgac ttctatcttt actaatgaaa
    31321 gcatcaagat atggacatat aatctagaga ctgtacttgc tgaaaagtta gaaacaatca
    31381 tcagtagggg actagcttcg acgcgtccac gtgatcgata tgatcttttc accttgtata
    31441 aacttagaaa agaagagatt aatcttgaag tattaaaaaa tgcacttgag aatacggcag
    31501 aaaaacgtaa aagtaaagat actatttata attgggaaga acaagtgaga ggaattgaaa
    31561 tttctgatta tcagaaagag ctatggattc gttatcaacg ccaatttaag tatgctaaag
    31621 atatctcatt tgataactct gttcaggtca ttagggaaat tatgcaacaa atattttagt
    31681 acaaaagtaa ctcattagta aagcagtgag ttgctttttt tattccaata actccaaaaa
    31741 tgtgataaaa atttcaacta ctcttatcta taataaagct acctgttctt tgaaaattga
    31801 atccactccg tcttgattag cgtgcctgtg taagtaggga ctgagagtat ttccctgtga
    31861 agggcaactg gcacaagacg tgtgtgagaa ttttctaaca gacacggagt ttatcgttac
    31921 cagacttaaa cgatgcgaca aactagataa aggagttaat catgaaggta gtaaacttgt
    31981 atgatttgaa acaaatggga aataaaggtg gttgtaccat ccaattgatt catcactttc
    32041 cttttggtat gggcttagga catctcaaaa aagactacat tgaatttaaa cgtgttggta
    32101 tcgttgatgg gaaggcagta gaagtcactc ttcgagaacc ttattcgaga gatctactgc
    32161 aggttgtcaa gtcgattaag caacgtcaga aattgatagc ttatcgttat aaagaaggaa
    32221 agctgctatt tgtgaagaag gaggcatcag atgtcctctg aacaacagga acgaatggca
    32281 gttcaatatg cggagcgtag tcttttattt actgtcaaaa gtctcttaaa aattctagaa
    32341 tggtctagac gtcaggcttt agcacaggat tccgcctata agataggggt gcagaaatta
    32401 gaagaattgc tacaatctcc ttattcgatt gatacgatta atctgaaaaa agatttttta
    32461 gacaaaccaa ttgatataga gaaatttaaa gcttttttag aaaaagaaga gattccttta
    32521 gccatcgctt ggcaagggga ttctctacat ttctacacga aagaccgttc gattctggac
    32581 aatcatttag accatctgtt agaaaaaatg gttaatgatc cggagaaatt agctgatttt
    32641 accatggata agtcattaga cgatgcaatt gatgaggcga aatcccaaat tacctttaga
    32701 caagaagggg ccgtcaaaca gaaagagatg gtgagatgat gtacagtgga aagaaattcc
    32761 tactattttc actgttaggt atcttactag gctatctttt tcatcgtttg acgcttttgt
    32821 atgattccta tactggaaat acattagata aatggactca tcttctgatg gaaggtcaag
    32881 atgaagttct tcagtcgcca tggaatgttt cctttactgg aaaatccagt gctttttttc
    32941 tactaggctt tgtgatgatg ttgctggttt atctttattt agagactggc aaaaaacaat
    33001 accgagaagg ggtagaatac gggagcgccc gttttggaac tctaaaagaa aagaagctct
    33061 tttacggtaa ggaattttct catgatacga tcttagctca agatgttcgt ttgacattat
    33121 tagataaaaa acccccccaa tatgatagaa ataagaatat tgcggtgatc ggaggttcag
    33181 gaagtgggaa gacatttcgc tttgtgaaac ctaatcttat tcagatgaat agttctaata
    33241 ttgtagtgga tcctaaagat cacttggccg aaaaaacagg caaactcttt ttagaacatg
    33301 gctatcaagt aaaggtgcta gatttagtca atatgaagaa ctcagatggc ttcaatcctt
    33361 ttcgctatat agagacagaa aatgatttga atcgcatgct gacggtttat tttaataaca
    33421 ccaaaggctc tggctcccga agtgacccat tttgggatga agcttctatg actttggttc
    33481 gagctttagc ctcttacttg gtcgatttct ataatccacc caaaacaaga gaacagctca
    33541 ttgaagagag tcgtttgagt caaaaagaat accagaactt gttgaaacgt caaaaaaaag
    33601 aagtggaaga gcgaaaaaaa cgaggacgtt atccaagttt tgctgaaatc tcaaaactca
    33661 ttaaacactt atctaagggt gaaaaccaag aaaaaagtgt cttagaaatt ctatttgaaa
    33721 attatgctaa aaagtatggc actgaaaatt ttaccatgcg aaattgggca gatttccaaa
    33781 attataagga taagactctg gattctgtta tagctgtaac cactgctaaa tttgccctct
    33841 tcaatattca aagtgtcatg gatttgacca aaagagatac ccttgatatg aagacatggg
    33901 gccaggaaaa atcaatggtt tacttagtta tcccagataa cgatagtacc tttcgctttc
    33961 tttcagccct ctttttttca accgtatttc aaaccctaac aagacaagca gatattgatt
    34021 ttaagggtca attgcctctt catgtgagag tctacttaga tgagttcgca aatataggag
    34081 aaatcccaga ttttgctgaa caaacctcaa cagtccgttc tcgaaatatg agtctcgttc
    34141 ccattcttca aaatattgcc caacttcaag ggctctataa agaaaaagaa gcttggaaaa
    34201 ccattttggg gaactgtgat agcttagtct acttaggtgg gaatgatgaa gataccttta
    34261 aatttatgag tggcttactc ggtaaacaaa ccattgatgt tcgaaatact agtcgttcct
    34321 ttggccagac aggttcagga tccctttctc atcaaaagat tgctcgtgat ttaatgacac
    34381 ctgatgaggt cggaaatatg aaacggcatg aatgcttggt tcgaattgcc aatatgcctg
    34441 tctttaaaag caaaaaatac aattccacta agcatccaaa ctggaaatac ctagccaatc
    34501 aagaaaccga tgaacggtgg tggaactatc aaatcaatcc tttgaatcaa agacaagaaa
    34561 atcatcttga aggccttaga attcgtgatt taacttttga atctagttta aaataaaaat
    34621 agaaaagagg aaatagatga ttacgcattt taaaggtttt gtttatggag tagacgcaag
    34681 tgctatgttt gcacaagcta tgtctttgtt acagaagggt ttgattgcgg ttggtgcctt
    34741 tctcgttgtt gtggggattg tcaatcttgc aaccaacatt aaagatggtg gaccaggtgt
    34801 tcggaatgcc attctggaaa ttgtcggtgg tgttatggta ggggctgctg gagcctttgt
    34861 aactcaaatt tcaatttagg aggataaaca atgacatgaa tcttagttta gtctcaccct
    34921 ttgtttacct tgcatctgaa aaaatatcag ctgaaaattt atttgaaggg tttaatgtag
    34981 atttacaatc tacggtagat ctgattaaat ccctatctag ctacaatcca acagtttgga
    35041 cttatatgtc tagtattact aaaagtgtca tgcagcctct tggagttgcg attttatcag
    35101 ttgttctcat cttagaattt tcgaagatgg caaagaaaat tgctaactca ggaggagcga
    35161 tgacctttga agcattagcg ccgatgttga ttagttatat catggtcgca gtcgtgatta
    35221 ccaatactac cgttattgta gaagccatca tcgggattgc gagtcacgcc attgaacaag
    35281 tggcctcaat tgtggctcac ggtggggcaa agtatgatac catctctgga ttaaaaggtt
    35341 caggatttat tggccggatg attgtgggct ttttcgccct cctcatttgg ctagttcgga
    35401 tagtaagtgc agccatggtt aaccttttgg tatctattcg atttattcaa ctctacctta
    35461 tgattccatt tgcccctctt acgattccaa catttttaag tgatgaatgg aagtctattg
    35521 gtattggcta tttaaaaaat attatggttt atgcggtaca aggggttctc atttttctga
    35581 ttgtttctct tgttccttta tttgaatctg ctgggaaaat agctgtttca aatggtgcag
    35641 gagtcttgca atcacttgcg attatgtttg gtagtttggt acaagctatc ttactgatta
    35701 ttgccctcgt tggttctcaa cgtacggctc gctcaatctt aggtatgtaa ttagataaag
    35761 gctaggaagt gattgcttct tagccttttt agaaaggaaa gtcatgaata cacgtgtctt
    35821 taaagacatc tcaaaatacc aacacagggc ttggttaggt ttcaccacaa gacaaatcat
    35881 ctttgtttta ccagccttta ttgtcacaat tattgttttg ggcttgaatc tctttttctg
    35941 gcaatttgga gattggtttg tttacggttt tgtgtttgct tttaccatcc ccctcatgct
    36001 ttttggagtc tataaaccca atgatttata ttttgaacat tatttgaaat accgtcttca
    36061 ttttgaacta acggttcccc tacgcacaat tacaggaaag aaaggacctg aacatgaaaa
    36121 gaaaatcaaa tacattaaag aaacaaaaaa cttcaatgac taatcagaaa gaagtagtta
    36181 aaggaaaaaa agaggaagtg ttaccatcga cggctaatac tctttcctat caagccctgt
    36241 atcaaaatgg tctgatgcag gtaaaagaag attatttctc acaaagctat ttacttggtg
    36301 atgtcaatta ccagactgtt ggtttagaag ataagggcgc aatcattgag aagtattctg
    36361 atttgattaa ctccctagac gaccaaacca acttccaatt gactatcttt aataaaagat
    36421 tgaatttaga aaagtttaga caaagtgttt tgtatgagga aaaagaagat gggtatgata
    36481 gctatcgtaa agaattgaat cggatgatga atcagaattt agacagtggt gaaaataact
    36541 tttcagctgt gaaactgatt agctttggta gaaaggattc taatcccaaa caagcctatc
    36601 gttccttgtc tcaaattgga gaatatttca agagtggttt ctcagaaatt gatgctcgat
    36661 ttgaatcttt ggctggagaa gaacgggtga acttgctggc agatatgctt agaggagaac
    36721 accatcttcc tttttcttac cgtgatttaa cgagatctgg tcagacaact cgtcacttca
    36781 tagcacctaa tctcttggat tttaaaaaca agaattacct acaaatcaat gaccgcttat
    36841 tgcagattgt ctatgtcaga gactacggta tggaattagg agatcagttt atttgagacc
    36901 tcatgcaagg agatttggaa ttgattgtga gcctccatgc tcaaagttcg accaaggcgg
    36961 atgctatgaa gaaactacga acaaagaaga ccttgatgga atcccaaaag attggggaac
    37021 aacaaaaact tgctcgtaca ggtatctatt tggaaaaagt aggtcatgta ttagaaagca
    37081 atatcgatga agctgaggaa ctcttaaaaa ccatgaccga gacaggagat aaactatttc
    37141 aaacagtatt cttgattggt gtttttggtc aggatgaaga agaacttaaa caagctctag
    37201 atacgattca acaagtggcc ggctcaaatg acctaatgat tgataaacta ccatatatgc
    37261 aagaagcagc ctttaatagt ttgctgccat ttggttgtga ttttttagag ggagtatcac
    37321 ggagtttatt aacatccaat atagcagtga actctccatg gacttcagta gacttacaag
    37381 accgtagtgg aaaatattac ggtatcaatc aaatctcaag caatattatt accattgatc
    37441 gcagcctatt aaatacaccg tctggtctga ttttagggac atctggagct gggaaaggga
    37501 tggcaaccaa gcatgaaatt atcacgaccc aaatcaagga atctggtgaa aatactgaaa
    37561 ttatcatcgt ggatccagaa gcagaataca gtgtcattgg acgagctttt ggtggagaaa
    37621 tgattgatat tgcgcccgat tcccaaactt atctcaatgt ccttgatttg tctgaggaaa
    37681 atatggatga agatcctgta aaggtaaaat cagaatttct tttatccttt atcggcaagt
    37741 tattggatag aaaaatggat ggaagagaaa aatcgattat cgaccgagtc acaagactca
    37801 cctatcagtc atttaaagag ccttctttgg aagaatgggt ctttgtcttg agccaacaac
    37861 cagaagaaga agcgcagaat ttggcacttg atatggaact gtatgtcgaa ggttctcttg
    37921 atattttttc tcataagacc aatattcaga caggatctaa tttcttgatt tataacgtta
    37981 agaagttagg agatgagctg aaacaaatcg cccttatggt tgtttttgat cagatatgga
    38041 atcgtgtcgt tcggaatcaa aaattaggga agaagacctg gatttatttt gatgaaatgc
    38101 agcttctctt attagataaa tatgccagtg atttcttctt taaattgtgg agtcgtgtca
    38161 gaaaatatgg agccagtctg actggaataa ctcaaaacgt cgaaacctta ttgttagatc
    38221 caaatggtag acggattatt gcaaatagtg aatttatgat tcttctcaag caagcaaaaa
    38281 atgaccgaga agaactggtt caactcttag gcttgtcaaa agaactcgaa aaatacctag
    38341 tcaatccaga aaaaggagca ggactgataa aagctggttc agttgtcgta ccatttaaaa
    38401 ataagattcc tcaaggtact caattgtttg atattatgag tacggatcct gataaaatgg
    38461 cttctaatta aggggaaggt aaatgaagga taaaagagaa atcatacgtg cccgaaaagc
    38521 atttagaaga agtctaaaag atgagaagaa attcttgaaa caaggaaaga aggaggtgag
    38581 gaaacagaaa aaagattccg ctgtactgga tgaaaaagca tggaaaaaag agataaaaga
    38641 aaagctagag gagatgagag aagcttcaaa ggagagagta aaacaagcaa atgaagacta
    38701 caatcatatt cttcaaaata gtcctccatc ttttttgaat cgtaaagaat taagagacag
    38761 acgattacct catgctagga aacgattgaa aatagccaag aagcaattta gagaagccaa
    38821 ggtagaagca aaagaagaaa gaaaagagag tcgtaaagaa agaaaaacca atcaaaaatt
    38881 tctctacggt caggaatcga aacaaaaatc taattttttc tttcaaggga agagtttaga
    38941 agaattaaaa gctaagaaag aagtcaaggc tgctaaagaa aatttaaaat ctactaaaca
    39001 agcctataag tacaaaaaag tcagtaggaa agccaaaact tttctttatg tccttggacg
    39061 tgaaggtgga gagttagctt cagaaaatga agatttagaa ggctatcgca cacttcaaga
    39121 gaccattaga aaagggaaac gctacagtcg gctttcttat aatcttggaa aagctagtgt
    39181 caaaacagga caagcaacag gtcgttttac caagaaaaga ctgaccaaca caaaagagcg
    39241 ataccatcat tttaaggatg gaaaaggatg gaaactagca aaagataacc caagttcctt
    39301 taagaatcgg tttcgaaaat taaagaaaca aggtctttca agtgtccaaa atatctatca
    39361 aaaactaaaa gcagcctttt ccttctttac atttgcggct ggaaatcctg caacatggat
    39421 agttggagga atagtctttc ttcttttact tatgatgagc ttcttcttag gattttcatc
    39481 tgctagtttg attcaacaag atgaatttga attaacaaaa gcttataccc acctaacttg
    39541 ggaagatgca gaacatactc gcacaaatga caaaggaatt acctattaca caaaagttga
    39601 tgatgtgatg gggtatatga actttaaatt ccatgactat gagttacaga aaccagttca
    39661 cttatttagt tcagaaactt acaaggatta tctgtctact ttgtggcatg atttaaacga
    39721 tggtgatgat ttgaaatcca tgcaagacct ctatgaaact cctaagtata aactatcgaa
    39781 agacgatcaa gaggaaataa aggaactaaa agaagaaggt gtgtatgctt ccatgcagga
    39841 attagacaat ccatttgagg gacaaagcaa cgaagatagt ctaaccatga cttatcgtta
    39901 tggatactat gatttagatg ggaaacctac tcttcaggag tacatcctac tagaagcaaa
    39961 ggctcaccaa acgattgtcg caccaatgga tgcagttgta tctctagatg gtgacaatat
    40021 tattctcact aacggaaaag gagagaatga gagtcgatta accttgtatt ctattcataa
    40081 tggccgtgcg attgagggga caagagtcct aacgggtgat attattggtg aaacaccaga
    40141 cgatacaggt ttgaaagttt cctatcaaaa gtataagaac aagaaagaaa aattggtgta
    40201 tgtcaatccg caattttatt ttccaaaagt cattcaactt cagaccacta tcttacctgc
    40261 cattggtcag tttggtgggg atgagtttga acgagcaaaa catatttatg attttttgaa
    40321 atctcaaggc gtaagtcccc aagccattgc ggctatttta ggaaattggt ctgtagagtc
    40381 ttctattaat ccaaaacgag ctgaaggaga ttatttatct cctccagttg gcgctaccga
    40441 ttcctcatgg gatgatgaaa gctggttagc gattggaggt ccagccattt atagtggtgc
    40501 ttatcctaat attcttcata gaggtttggg gttagggcaa tggacggata cttcagatgg
    40561 ttcaacacgt tatacagctt tattgaatta tgcacatagc aaaaataaga agtggtatga
    40621 tttagacctc caacttgatt ttatgcttca tggggatagt ccttactacc aaagttggtt
    40681 aaaagatttc tttaaaaata cgggcagtgc agccaatctc gcccaactct tcctcaccta
    40741 ttgggaggga aattctggtg acaaattact ggaaagacaa accagagcaa cggaatggta
    40801 ttaccaaatt gaaaaaggct tcagccaaac aaatggagga caggcaaaaa gtgacccaca
    40861 atcccttgaa ggggttcgtg gggacttgta tgatcattct gttcctggtg gtggagatgg
    40921 tatggcctat gcctatggac aatgtacatg gggtgttgcg gctcgtatga atcaattagg
    40981 cttaaaatta aaaggaagta acggagagaa gatttcaatc attaatacca tgggaaatgg
    41041 tcaggactgg gttgcgacag cttcaagtct tggtggggaa actggctcta caccaagagc
    41101 aggtgctatt gtttcttttg tgggaggtac acatggcaca ccagcagact atggtcatgt
    41161 agcttttgta ggtgcgagac gtttctaact gaaaaggtta gacacgttct
//
